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1979 …2020
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Research Output 1990 2020

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2006
88 Citations (Scopus)

Angiogenesis in atherogenesis

Herrmann, J., Lerman, L. O., Mukhopadhyay, D., Napoli, C. & Lerman, A., Sep 2006, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 26, 9, p. 1948-1957 10 p.

Research output: Contribution to journalArticle

Atherosclerosis
Carcinogenesis
Cardiovascular Diseases
16 Citations (Scopus)

Atherosclerotic process, renovascular disease and outcomes from bench to bedside

Lerman, L. O. & Chade, A. R., Nov 2006, In : Current Opinion in Nephrology and Hypertension. 15, 6, p. 583-587 5 p.

Research output: Contribution to journalArticle

Renal Artery Obstruction
Kidney
Renal Hypertension
Stents
Oxidative Stress
29 Citations (Scopus)

Autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the diabetic mouse hindlimb

Sica, V., Williams-Ignarro, S., De Nigris, F., D'Armiento, F. P., Lerman, L. O., Balestrieri, M. L., Maione, C., Palagiano, A., Rossiello, L., Ignarro, L. J. & Napoli, C., Dec 15 2006, In : Cell Cycle. 5, 24, p. 2903-2908 6 p.

Research output: Contribution to journalArticle

Hindlimb
Medical problems
Cell- and Tissue-Based Therapy
Bone Marrow Cells
Bone
18 Citations (Scopus)

Bosentan preserves endothelial function in mice overexpressing APP

Elesber, A. A., Bonetti, P. O., Woodrum, J. E., Zhu, X. Y., Lerman, L. O., Younkin, S. G. & Lerman, A., Mar 2006, In : Neurobiology of Aging. 27, 3, p. 446-450 5 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Vasodilation
Endothelium
Alzheimer Disease
bosentan
39 Citations (Scopus)

Chronic antioxidant supplementation impairs coronary endothelial function and myocardial perfusion in normal pigs

Versari, D., Daghini, E., Rodriguez-Porcel, M. G., Sattler, K., Galili, O., Pilarczyk, K., Napoli, C., Lerman, L. O. & Lerman, A., Mar 2006, In : Hypertension. 47, 3, p. 475-481 7 p.

Research output: Contribution to journalArticle

Dobutamine
Adenosine
Swine
Perfusion
Antioxidants
85 Citations (Scopus)

Coronary endothelial dysfunction is associated with erectile dysfunction and elevated asymmetric dimethylarginine in patients with early atherosclerosis

Elesber, A. A., Solomon, H., Lennon, R. J., Mathew, V., Prasad, A., Pumper, G., Nelson, R. E., McConnell, J. P., Lerman, L. O. & Lerman, A., Apr 2006, In : European Heart Journal. 27, 7, p. 824-831 8 p.

Research output: Contribution to journalArticle

Erectile Dysfunction
Atherosclerosis
Coronary Artery Disease
Nitric Oxide Synthase
HDL Lipoproteins
5 Citations (Scopus)

Dietary reversal of experimental hypercholesterolemia improves endothelial dysfunction of epicardial arteries but not of small coronary vessels in pigs

Sattler, K. J. E., Galili, O., Rodriguez-Porcel, M. G., Krier, J. D., Lerman, L. O. & Lerman, A., Oct 2006, In : Atherosclerosis. 188, 2, p. 301-308 8 p.

Research output: Contribution to journalArticle

Hypercholesterolemia
Coronary Vessels
Swine
Arteries
Diet
78 Citations (Scopus)

Dysregulation of the ubiquitin-proteasome system in human carotid atherosclerosis

Versari, D., Herrmann, J., Gössl, M., Mannheim, D., Sattler, K., Meyer, F. B., Lerman, L. O. & Lerman, A., Sep 2006, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 26, 9, p. 2132-2139 8 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Proteasome Endopeptidase Complex
Ubiquitin
Apoptosis
Oxidative Stress
33 Citations (Scopus)
Endothelin A Receptors
Hypercholesterolemia
Microvessels
Endothelins
Kidney
38 Citations (Scopus)

Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension

Rodriguez-Porcel, M. G., Zhu, X. Y., Chade, A. R., Amores-Arriaga, B., Caplice, N. M., Ritman, E. L., Lerman, A. & Lerman, L. O., Mar 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 290, 3

Research output: Contribution to journalArticle

Microvessels
Hypertension
Blood Volume
Adenosine
Left Ventricular Hypertrophy
9 Citations (Scopus)

In vivo veritas: Thrombosis mechanisms in animal models

Napoli, C., De Nigris, F., Pignalosa, O., Lerman, A., Sica, G., Fiorito, C., Sica, V., Chade, A. & Lerman, L. O., Aug 1 2006, In : Scandinavian Journal of Clinical and Laboratory Investigation. 66, 5, p. 407-427 21 p.

Research output: Contribution to journalArticle

Animals
Thrombosis
Animal Models
Venous Thrombosis
Hemodynamics
95 Citations (Scopus)

Lipoprotein-associated phospholipase A2 is an independent marker for coronary endothelial dysfunction in humans

Yang, E. H., McConnell, J. P., Lennon, R. J., Barsness, G. W., Pumper, G., Hartman, S. J., Rihal, C. S., Lerman, L. O. & Lerman, A., Jan 2006, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 26, 1, p. 106-111 6 p.

Research output: Contribution to journalArticle

1-Alkyl-2-acetylglycerophosphocholine Esterase
Coronary Vessels
Acetylcholine
Vasoconstriction
Coronary Artery Disease
62 Citations (Scopus)

Mild renal insufficiency is associated with reduced coronary flow in patients with non-obstructive coronary artery disease

Chade, A. R., Brosh, D., Higano, S. T., Lennon, R. J., Lerman, L. O. & Lerman, A., Jan 2006, In : Kidney International. 69, 2, p. 266-271 6 p.

Research output: Contribution to journalArticle

Renal Insufficiency
Coronary Artery Disease
Glomerular Filtration Rate
Chronic Renal Insufficiency
Kidney
37 Citations (Scopus)

Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice

Napoli, C., Williams-Ignarro, S., De Nigris, F., Lerman, L. O., D'Armiento, F. P., Crimi, E., Byrns, R. E., Casamassimi, A., Lanza, A., Gombos, F., Sica, V. & Ignarro, L. J., Jul 4 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 27, p. 10479-10484 6 p.

Research output: Contribution to journalArticle

Atherosclerotic Plaques
Rupture
Exercise
Arginine
Natural History
30 Citations (Scopus)

Plasma 8-iso-prostaglandin F, a marker of oxidative stress, is increased in patients with acute myocardial infarction

Elesber, A. A., Best, P., Lennon, R. J., Mathew, V., Rihal, C. S., Lerman, L. O. & Lerman, A., Apr 2006, In : Free Radical Research. 40, 4, p. 385-391 7 p.

Research output: Contribution to journalArticle

Oxidative stress
Dinoprost
Oxidative Stress
Myocardial Infarction
Plasmas
71 Citations (Scopus)

Prognostic value of circulating pregnancy-associated plasma protein levels in patients with chronic stable angina

Elesber, A. A., Conover, C. A., Denktas, A. E., Lennon, R. J., Holmes, D., Overgaard, M. T., Christiansen, M., Oxvig, C., Lerman, L. O. & Lerman, A., Jul 2006, In : European Heart Journal. 27, 14, p. 1678-1684 7 p.

Research output: Contribution to journalArticle

Stable Angina
Blood Proteins
Coronary Artery Disease
Pregnancy
Acute Coronary Syndrome
65 Citations (Scopus)

Rethinking primary prevention of atherosclerosis-related diseases

Napoli, C., Lerman, L. O., De Nigris, F., Gossl, M., Balestrieri, M. L. & Lerman, A., Dec 2006, In : Circulation. 114, 23, p. 2517-2527 11 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Primary Prevention
Disease Progression
Atherosclerosis
Cardiovascular Diseases
7 Citations (Scopus)

Review - 3D micro CT imaging of renal micro-structural changes

Gössl, M., Bentley, M. D. & Lerman, L. O., Mar 2006, In : Nephron - Clinical Practice. 103, 2

Research output: Contribution to journalArticle

Kidney
Nephrons
Chronic Renal Insufficiency
X-Ray Microtomography
Renal Hypertension
37 Citations (Scopus)

Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension

Zhu, X. Y., Daghini, E., Chade, A. R., Rodriguez-Porcel, M. G., Napoli, C., Lerman, A. & Lerman, L. O., Aug 2006, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 26, 8, p. 1746-1752 7 p.

Research output: Contribution to journalArticle

Microcirculation
Oxidative Stress
Hypertension
Antioxidants
Microvessels
106 Citations (Scopus)

Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia

Chade, A. R., Zhu, X., Mushin, O. P., Napoli, C., Lerman, A. & Lerman, L. O., Aug 2006, In : FASEB Journal. 20, 10

Research output: Contribution to journalArticle

Renal Artery Obstruction
Simvastatin
ischemia
angiogenesis
Ischemia
21 Citations (Scopus)

The Porcine Remnant Kidney Model of Chronic Renal Insufficiency

Misra, S., Gordon, J. D., Fu, A. A., Glockner, J., Chade, A. R., Mandrekar, J., Lerman, L. O. & Mukhopadhyay, D., Oct 2006, In : Journal of Surgical Research. 135, 2, p. 370-379 10 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Swine
Kidney
Nephrectomy
Arterial Pressure
52 Citations (Scopus)

Vascular wall elasticity measurement by magnetic resonance imaging

Woodrum, D. A., Romano, A. J., Lerman, A., Pandya, U. H., Brosh, D., Rossman, P. J., Lerman, L. O. & Ehman, R. L., Sep 2006, In : Magnetic Resonance in Medicine. 56, 3, p. 593-600 8 p.

Research output: Contribution to journalArticle

Elasticity
Elasticity Imaging Techniques
Blood Vessels
Magnetic Resonance Imaging
Pathologic Constriction
2007
3 Citations (Scopus)

All oxidase roads lead to angiotensin, too

Lerman, L. O. & Lerman, A., Apr 2007, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 4, p. 703-704 2 p.

Research output: Contribution to journalArticle

Xanthine Oxidase
Angiotensins
Superoxides
Angiotensin II
Oxidoreductases
26 Citations (Scopus)

Antioxidant vitamins induce angiogenesis in the normal pig kidney

Daghini, E., Zhu, X. Y., Versari, D., Bentley, M. D., Napoli, C., Lerman, A. & Lerman, L. O., Jul 2007, In : American Journal of Physiology - Renal Physiology. 293, 1

Research output: Contribution to journalArticle

Vitamins
Swine
Antioxidants
Kidney
Oxidative Stress
4 Citations (Scopus)

Assessment of Myocardial Microvascular Function: New Opportunities in Fast Computed Tomography

Daghini, E. & Lerman, L. O., Jan 2007, In : Trends in Cardiovascular Medicine. 17, 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

Microcirculation
Tomography
Capillary Permeability
Cardiovascular Diseases
Perfusion
93 Citations (Scopus)

Assessment of renal hemodynamics and function in pigs with 64-section multidetector CT: Comparison with electron-beam CT

Daghini, E., Primak, A. N., Chade, A. R., Krier, J. D., Zhu, X. Y., Ritman, E. L., McCollough, C. H. & Lerman, L. O., May 2007, In : Radiology. 243, 2, p. 405-412 8 p.

Research output: Contribution to journalArticle

Swine
Hemodynamics
Electrons
Kidney
Renal Circulation
68 Citations (Scopus)

Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia

Baker, A. H., Sica, V., Work, L. M., Williams-Ignarro, S., De Nigris, F., Lerman, L. O., Casamassimi, A., Lanza, A., Schiano, C., Rienzo, M., Ignarro, L. J. & Napoli, C., Feb 27 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 9, p. 3597-3602 6 p.

Research output: Contribution to journalArticle

Metalloproteases
Brain Ischemia
Bone Marrow Cells
Brain
Cell- and Tissue-Based Therapy
85 Citations (Scopus)

Chronic proteasome inhibition contributes to coronary atherosclerosis

Herrmann, J., Saguner, A. M., Versari, D., Peterson, T. E., Chade, A., Olson, M., Lerman, L. O. & Lerman, A., Oct 2007, In : Circulation Research. 101, 9, p. 865-874 10 p.

Research output: Contribution to journalArticle

Proteasome Inhibitors
Proteasome Endopeptidase Complex
Coronary Artery Disease
Anticholesteremic Agents
Cholesterol
43 Citations (Scopus)

Comparison of mathematic models for assessment of glomerular filtration rate with electron-beam CT in pigs

Daghini, E., Juillard, L., Haas, J. A., Krier, J. D., Romero, J. C. & Lerman, L. O., Feb 2007, In : Radiology. 242, 2, p. 417-424 8 p.

Research output: Contribution to journalArticle

Mathematics
Glomerular Filtration Rate
Inulin
Swine
Electrons
28 Citations (Scopus)

Coronary endothelial dysfunction and hyperlipidemia are independently associated with diastolic dysfunction in humans

Elesber, A. A., Redfield, M. M., Rihal, C. S., Prasad, A., Lavi, S., Lennon, R., Mathew, V., Lerman, L. O. & Lerman, A., Jun 2007, In : American Heart Journal. 153, 6, p. 1081-1087 7 p.

Research output: Contribution to journalArticle

Hyperlipidemias
Linear Models
Heart Failure
HDL Cholesterol
Myocardial Ischemia
18 Citations (Scopus)
X-Ray Microtomography
Hypercholesterolemia
Coronary Vessels
Capillary Permeability
Tomography
141 Citations (Scopus)

Early experimental obesity is associated with coronary endothelial dysfunction and oxidative stress

Galili, O., Versari, D., Sattler, K. J., Olson, M. L., Mannheim, D., McConnell, J. P., Chade, A. R., Lerman, L. O. & Lerman, A., Feb 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 292, 2

Research output: Contribution to journalArticle

Oxidative Stress
Obesity
Swine
Insulin Resistance
Leptin
40 Citations (Scopus)

Effect of gestational hypercholesterolaemia on omental vasoreactivity, placental enzyme activity and transplacental passage of normal and oxidised fatty acids

Liguori, A., D'Armiento, F. P., Palagiano, A., Balestrieri, M. L., Williams-Ignarro, S., De Nigris, F., Lerman, L. O., D'Amora, M., Rienzo, M., Fiorito, C., Ignarro, L. J., Palinski, W. & Napoli, C., Dec 2007, In : BJOG: An International Journal of Obstetrics and Gynaecology. 114, 12, p. 1547-1556 10 p.

Research output: Contribution to journalArticle

Hypercholesterolemia
Fatty Acids
Placenta
Mothers
Oxidative Stress
66 Citations (Scopus)

Effects of a Pomegranate Fruit Extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis

de Nigris, F., Williams-Ignarro, S., Sica, V., Lerman, L. O., D'Armiento, F. P., Byrns, R. E., Casamassimi, A., Carpentiero, D., Schiano, C., Sumi, D., Fiorito, C., Ignarro, L. J. & Napoli, C., Jan 15 2007, In : Cardiovascular Research. 73, 2, p. 414-423 10 p.

Research output: Contribution to journalArticle

Punicaceae
Nitric Oxide Synthase Type III
Fruit
Atherosclerosis
Genes
36 Citations (Scopus)

Evaluation of porcine myocardial microvascular permeability and fractional vascular volume using 64-slice helical computed tomography (CT)

Daghini, E., Primak, A. N., Chade, A. R., Zhu, X., Ritman, E. L., McCollough, C. H. & Lerman, L. O., May 2007, In : Investigative Radiology. 42, 5, p. 274-282 9 p.

Research output: Contribution to journalArticle

Spiral Computed Tomography
Capillary Permeability
Blood Vessels
Swine
X Ray Computed Tomography
6 Citations (Scopus)

Examine thy heart with all diligence: Evaluation of cardiac function using fast computed tomography

Daghini, E., Ritman, E. L. & Lerman, L. O., Feb 2007, In : Hypertension. 49, 2, p. 249-256 8 p.

Research output: Contribution to journalArticle

Heart Function Tests
Tissue Survival
Coronary Circulation
Diastole
X Ray Computed Tomography
4 Citations (Scopus)

Frontiers in nephrology: Early atherosclerosis - A view beyond the lumen

Gossl, M., Lerman, L. O. & Lerman, A., Nov 2007, In : Journal of the American Society of Nephrology. 18, 11, p. 2836-2842 7 p.

Research output: Contribution to journalArticle

Vasa Vasorum
Nephrology
Atherosclerosis
Bone Marrow
Endothelium
11 Citations (Scopus)

Hypertension and hypercholesterolemia differentially affect the function and structure of pig carotid artery

Versari, D., Gossl, M., Mannheim, D., Daghini, E., Galili, O., Napoli, C., Lerman, L. O. & Lerman, A., Dec 2007, In : Hypertension. 50, 6, p. 1063-1068 6 p.

Research output: Contribution to journalArticle

Vasa Vasorum
Hypercholesterolemia
Carotid Arteries
Swine
Hypertension
9 Citations (Scopus)

Impaired myocardial perfusion reserve in experimental hypercholesterolemia is independent of myocardial neovascularization

Mannheim, D., Versari, D., Daghini, E., Gössl, M., Galili, O., Chade, A., Rajkumar, S. V., Ritman, E. L., Lerman, L. O. & Lerman, A., May 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 292, 5

Research output: Contribution to journalArticle

Hypercholesterolemia
Swine
Perfusion
Thalidomide
Oxidative Stress
47 Citations (Scopus)

Increased spatial vasa vasorum density in the proximal LAD in hypercholesterolemia-Implications for vulnerable plaque-development

Gössl, M., Versari, D., Mannheim, D., Ritman, E. L., Lerman, L. O. & Lerman, A., Jun 2007, In : Atherosclerosis. 192, 2, p. 246-252 7 p.

Research output: Contribution to journalArticle

Vasa Vasorum
Hypercholesterolemia
Blood Vessels
Atherosclerosis
X-Ray Microtomography
15 Citations (Scopus)

Lipoprotein-associated phospholipase A2: Review of its role as a marker and a potential participant in coronary endothelial dysfunction

Lavi, S., Lavi, R., McConnell, J. P., Lerman, L. O. & Lerman, A., 2007, In : Molecular Diagnosis and Therapy. 11, 4, p. 219-226 8 p.

Research output: Contribution to journalArticle

1-Alkyl-2-acetylglycerophosphocholine Esterase
Atherosclerosis
Inflammation
LDL Lipoproteins
Lipoproteins
172 Citations (Scopus)

Local production of lipoprotein-associated phospholipase A2 and lysophosphatidylcholine in the coronary circulation: Association with early coronary atherosclerosis and endothelial dysfunction in humans

Lavi, S., McConnell, J. P., Rihal, C. S., Prasad, A., Mathew, V., Lerman, L. O. & Lerman, A., May 2007, In : Circulation. 115, 21, p. 2715-2721 7 p.

Research output: Contribution to journalArticle

1-Alkyl-2-acetylglycerophosphocholine Esterase
Coronary Circulation
Lysophosphatidylcholines
Coronary Artery Disease
Inflammation
10 Citations (Scopus)

New frontiers in the evaluation of cardiac patients for noncardiac surgery

Lavi, R., Lavi, S., Daghini, E. & Lerman, L. O., Dec 2007, In : Anesthesiology. 107, 6, p. 1018-1028 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Redox-sensitive myocardial remodeling and dysfunction in swine diet-induced experimental hypercholesterolemia

Zhu, X. Y., Daghini, E., Rodriguez-Porcel, M. G., Chade, A. R., Napoli, C., Lerman, A. & Lerman, L. O., Jul 2007, In : Atherosclerosis. 193, 1, p. 62-69 8 p.

Research output: Contribution to journalArticle

Hypercholesterolemia
Oxidation-Reduction
Swine
Diet
Transforming Growth Factors
17 Citations (Scopus)

Relation of Depression to Coronary Endothelial Function

Yang, E. H., Lerman, S., Lennon, R. J., Simari, R. D., Lerman, L. O. & Lerman, A., Apr 15 2007, In : American Journal of Cardiology. 99, 8, p. 1134-1136 3 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
Acetylcholine
C-Reactive Protein
Disease Progression
Body Mass Index
28 Citations (Scopus)

Role of renal cortical neovascularization in experimental hypercholesterolemia

Chade, A. R., Krier, J. D., Galili, O., Lerman, A. & Lerman, L. O., Oct 2007, In : Hypertension. 50, 4, p. 729-736 8 p.

Research output: Contribution to journalArticle

Hypercholesterolemia
Kidney
Thalidomide
Hemodynamics
Inflammation
52 Citations (Scopus)

Simvastatin prevents coronary microvascular remodeling in renovascular hypertensive pigs

Zhu, X. Y., Daghini, E., Chade, A. R., Napoli, C., Ritman, E. L., Lerman, A. & Lerman, L. O., Apr 2007, In : Journal of the American Society of Nephrology. 18, 4, p. 1209-1217 9 p.

Research output: Contribution to journalArticle

Renovascular Hypertension
Simvastatin
Swine
Microvessels
Intercellular Signaling Peptides and Proteins
93 Citations (Scopus)

Smoking is associated with epicardial coronary endothelial dysfunction and elevated white blood cell count in patients with chest pain and early coronary artery disease

Lavi, S., Prasad, A., Yang, E. H., Mathew, V., Simari, R. D., Rihal, C. S., Lerman, L. O. & Lerman, A., May 2007, In : Circulation. 115, 20, p. 2621-2627 7 p.

Research output: Contribution to journalArticle

Chest Pain
Leukocyte Count
Coronary Artery Disease
Smoking
Acetylcholine
55 Citations (Scopus)

The importance of reendothelialization after arterial injury

Versari, D., Lerman, L. O. & Lerman, A., Jun 2007, In : Current Pharmaceutical Design. 13, 17, p. 1811-1824 14 p.

Research output: Contribution to journalArticle

Atherosclerosis
Atherosclerotic Plaques
Endothelium
Wounds and Injuries
Endothelial Cells