• 22185 Citations
  • 68 Scopus h-Index
1979 …2020

Research output per year

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Article
2003
9 Scopus citations

Glycoxidation of Low-Density Lipoprotein Increases TUNEL Positivity and CPP32 Activation in Human Coronary Cells

De Nigris, F., Tajana, G., Condorelli, M., D'Armiento, F. P., Sica, G., Lerman, L. O. & Napoli, C., Jan 1 2003, In : Annals of the New York Academy of Sciences. 1010, p. 710-715 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
69 Scopus citations

Hypertension exacerbates the effect of hypercholesterolemia on the myocardial microvasculature

Rodriguez-Porcel, M., Lerman, A., Herrmann, J., Schwartz, R. S., Sawamura, T., Condorelli, M., Napoli, C. & Lerman, L. O., May 1 2003, In : Cardiovascular research. 58, 1, p. 213-221 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Lipid-lowering-independent effects of simvastatin on the kidney in experimental hypercholesterolaemia

Wilson, S. H., Chade, A. R., Feldstein, A., Sawamura, T., Napoli, C., Lerman, A. & Lerman, L. O., Apr 1 2003, In : Nephrology Dialysis Transplantation. 18, 4, p. 703-709 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Mechanisms of renal structural alterations in combined hypercholesterolemia and renal artery stenosis

Chade, A. R., Rodriguez-Porcel, M., Grande, J. P., Zhu, X., Sica, V., Napoli, C., Sawamura, T., Textor, S. C., Lerman, A. & Lerman, L. O., Jul 1 2003, In : Arteriosclerosis, thrombosis, and vascular biology. 23, 7, p. 1295-1301 7 p.

Research output: Contribution to journalArticle

130 Scopus citations

Oxidative stress-related increase in ubiquitination in early coronary atherogenesis.

Hermann, J., Gulati, R., Napoli, C., Woodrum, J. E., Lerman, L. O., Rodriguez-Porcel, M., Sica, V., Simari, R. D., Ciechanover, A. & Lerman, A., Sep 2003, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17, 12, p. 1730-1732 3 p.

Research output: Contribution to journalArticle

49 Scopus citations

Renal blood flow in hypercholesterolemic pigs is increased by chronic antioxidant treatment

De Nigris, F., Demontis, M. P., Rodriguez-Porcel, M., Anania, V., Lerman, L. O. & Napoli, C., Apr 1 2003, In : Journal of Veterinary Pharmacology and Therapeutics. 26, 2, p. 113-116 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
2004

Adventitial vasa vasorum heterogeneity among different vascular beds

Galili, O., Herrmann, J., Woodrum, J., Sattler, K. J., Lerman, L. O. & Lerman, A., Sep 1 2004, In : Journal of vascular surgery. 40, 3, p. 529-535 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Antioxidant Intervention Attenuates Myocardial Neovascularization in Hypercholesterolemia

Zhu, X. Y., Rodriguez-Porcel, M., Bentley, M. D., Chade, A. R., Sica, V., Napoli, C., Caplice, N., Ritman, E. L., Lerman, A. & Lerman, L. O., May 4 2004, In : Circulation. 109, 17, p. 2109-2115 7 p.

Research output: Contribution to journalArticle

100 Scopus citations

Antioxidant Intervention Blunts Renal Injury in Experimental Renovascular Disease

Chade, A. R., Rodriguez-Porcel, M., Herrmann, J., Zhu, X., Grande, J. P., Napoli, C., Lerman, A. & Lerman, L. O., Apr 1 2004, In : Journal of the American Society of Nephrology. 15, 4, p. 958-966 9 p.

Research output: Contribution to journalArticle

100 Scopus citations

Antioxidant intervention prevents renal neovascularization in hypercholesterolemic pigs

Chade, A. R., Bentley, M. D., Zhu, X., Rodriguez-Porcel, M., Niemeyer, S., Amores-Arriaga, B., Napoli, C., Ritman, E. L., Lerman, A. & Lerman, L. O., Jul 1 2004, In : Journal of the American Society of Nephrology. 15, 7, p. 1816-1825 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

Blood oxygen level-dependent measurement of acute intra-renal ischemia

Juillard, L., Lerman, L. O., Kruger, D. G., Haas, J. A., Rucker, B. C., Polzin, J. A., Riederer, S. J. & Romero, J. C., Mar 2004, In : Kidney international. 65, 3, p. 944-950 7 p.

Research output: Contribution to journalArticle

114 Scopus citations

Comparison of acute and chronic antioxidant interventions in experimental renovascular disease

Chade, A. R., Krier, J. D., Rodriguez-Porcel, M., Breen, J. F., McKusick, M. A., Lerman, A. & Lerman, L. O., Jun 1 2004, In : American Journal of Physiology - Renal Physiology. 286, 6 55-6, p. F1079-F1086

Research output: Contribution to journalArticle

69 Scopus citations

Cortical microvascular remodeling in the stenotic kidney: Role of increased oxidative stress

Zhu, X. Y., Chade, A. R., Rodriguez-Porcel, M., Bentley, M. D., Ritman, E. L., Lerman, A. & Lerman, L. O., Oct 1 2004, In : Arteriosclerosis, thrombosis, and vascular biology. 24, 10, p. 1854-1859 6 p.

Research output: Contribution to journalArticle

119 Scopus citations

Long-Term Antioxidant Intervention Improves Myocardial Microvascular Function in Experimental Hypertension

Rodriguez-Porcel, M., Herrman, J., Chade, A. R., Krier, J. D., Breen, J. F., Lerman, A. & Lerman, L. O., Feb 2004, In : Hypertension. 43, 2, p. 493-498 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Long-term combined beneficial effects of physical training and metabolic treatment on atherosclerosis in hypercholesterolemic mice

Napoli, C., Williams-Ignarro, S., De Nigris, F., Lerman, L. O., Rossi, L., Guarino, C., Mansueto, G., Di Tuoro, F., Pignalosa, O., De Rosa, G., Sica, V. & Ignarro, L. J., Jun 8 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 23, p. 8797-8802 6 p.

Research output: Contribution to journalArticle

89 Scopus citations

Relation of nonperfused myocardial volume and surface area to left ventricular performance in coronary microembolization

Malyar, N. M., Lerman, L. O., Gössl, M., Beighley, P. E. & Ritman, E. L., Oct 5 2004, In : Circulation. 110, 14, p. 1946-1952 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2005

Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb

Napoli, C., Williams-Ignarro, S., De Nigris, F., De Rosa, G., Lerman, L. O., Farzati, B., Matarazzo, A., Sica, G., Botti, C., Fiore, A., Byrns, R. E., Sumi, D., Sica, V. & Ignarro, L. J., Nov 22 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 47, p. 17202-17206 5 p.

Research output: Contribution to journalArticle

65 Scopus citations

Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress

De Nigris, F., Williams-Ignarro, S., Lerman, L. O., Crimi, E., Botti, C., Mansueto, G., D'Armiento, F. P., De Rosa, G., Sica, V., Ignarro, L. J. & Napoli, C., Mar 29 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 13, p. 4896-4901 6 p.

Research output: Contribution to journalArticle

116 Scopus citations

Concurrent treatment with renin-angiotensin system blockers and acetylsalicylic acid reduces nuclear factor κB activation and C-reactive protein expression in human carotid artery plaques

Sattler, K. J. E., Woodrum, J. E., Galili, O., Olson, M., Samee, S., Meyer, F. B., Zhu, X. Y., Lerman, L. O. & Lerman, A., Jan 1 2005, In : Stroke. 36, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

47 Scopus citations
52 Scopus citations

Effects of proteasome inhibition on the kidney in experimental hypercholesterolemia

Chade, A. R., Herrmann, J., Zhu, X., Krier, J. D., Lerman, A. & Lerman, L. O., Dec 8 2005, In : Journal of the American Society of Nephrology. 16, 4, p. 1005-1012 8 p.

Research output: Contribution to journalArticle

39 Scopus citations
30 Scopus citations

KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling

Cao, S., Fernandez-Zapico, M. E., Jin, D., Puri, V., Cook, T. A., Lerman, L. O., Zhu, X. Y., Urrutia, R. & Shah, V., Jan 21 2005, In : Journal of Biological Chemistry. 280, 3, p. 1901-1910 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Non-invasive evaluation of bilateral renal regional blood flow and tubular dynamics during acute unilateral ureteral obstruction

Pelaez, L. I., Juncos, L. A., Stulak, J. M., Lerman, L. O. & Romero, J. C., Jan 1 2005, In : Nephrology Dialysis Transplantation. 20, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Oxidative stress in obstructive sleep apnoea

Svatikova, A., Wolk, R., Lerman, L. O., Juncos, L. A., Greene, E. L., McConnell, J. P. & Somers, V. K., Nov 1 2005, In : European heart journal. 26, 22, p. 2435-2439 5 p.

Research output: Contribution to journalArticle

115 Scopus citations

Pathways of renal fibrosis and modulation of matrix turnover in experimental hypercholesterolemia

Chade, A. R., Mushin, O. P., Zhu, X., Rodriguez-Porcel, M., Grande, J. P., Textor, S. C., Lerman, A. & Lerman, L. O., Oct 1 2005, In : Hypertension. 46, 4, p. 772-779 8 p.

Research output: Contribution to journalArticle

56 Scopus citations
2006

Acute inhibition of the endogenous xanthine oxidase improves renal hemodynamics in hypercholesterolemic pigs

Daghini, E., Chade, A. R., Krier, J. D., Versari, D., Lerman, A. & Lerman, L. O., Mar 1 2006, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 290, 3, p. R609-R615

Research output: Contribution to journalArticle

14 Scopus citations

Autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the diabetic mouse hindlimb

Sica, V., Williams-Ignarro, S., De Nigris, F., D'Armiento, F. P., Lerman, L. O., Balestrieri, M. L., Maione, C., Palagiano, A., Rossiello, L., Ignarro, L. J. & Napoli, C., Dec 15 2006, In : Cell Cycle. 5, 24, p. 2903-2908 6 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Bosentan preserves endothelial function in mice overexpressing APP

Elesber, A. A., Bonetti, P. O., Woodrum, J. E., Zhu, X. Y., Lerman, L. O., Younkin, S. G. & Lerman, A., Mar 1 2006, In : Neurobiology of aging. 27, 3, p. 446-450 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Chronic antioxidant supplementation impairs coronary endothelial function and myocardial perfusion in normal pigs

Versari, D., Daghini, E., Rodriguez-Porcel, M., Sattler, K., Galili, O., Pilarczyk, K., Napoli, C., Lerman, L. O. & Lerman, A., Mar 1 2006, In : Hypertension. 47, 3, p. 475-481 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Coronary endothelial dysfunction is associated with erectile dysfunction and elevated asymmetric dimethylarginine in patients with early atherosclerosis

Elesber, A. A., Solomon, H., Lennon, R. J., Mathew, V., Prasad, A., Pumper, G., Nelson, R. E., McConnell, J. P., Lerman, L. O. & Lerman, A., Apr 1 2006, In : European heart journal. 27, 7, p. 824-831 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

Dietary reversal of experimental hypercholesterolemia improves endothelial dysfunction of epicardial arteries but not of small coronary vessels in pigs

Sattler, K. J. E., Galili, O., Rodriguez-Porcel, M., Krier, J. D., Lerman, L. O. & Lerman, A., Oct 1 2006, In : Atherosclerosis. 188, 2, p. 301-308 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Dysregulation of the ubiquitin-proteasome system in human carotid atherosclerosis

Versari, D., Herrmann, J., Gössl, M., Mannheim, D., Sattler, K., Meyer, F. B., Lerman, L. O. & Lerman, A., Sep 1 2006, In : Arteriosclerosis, thrombosis, and vascular biology. 26, 9, p. 2132-2139 8 p.

Research output: Contribution to journalArticle

81 Scopus citations
33 Scopus citations

Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension

Rodriguez-Porcel, M., Zhu, X. Y., Chade, A. R., Amores-Arriaga, B., Caplice, N. M., Ritman, E. L., Lerman, A. & Lerman, L. O., Mar 1 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 290, 3, p. H978-H984

Research output: Contribution to journalArticle

39 Scopus citations

In vivo veritas: Thrombosis mechanisms in animal models

Napoli, C., De Nigris, F., Pignalosa, O., Lerman, A., Sica, G., Fiorito, C., Sica, V., Chade, A. & Lerman, L. O., Aug 1 2006, In : Scandinavian Journal of Clinical and Laboratory Investigation. 66, 5, p. 407-428 22 p.

Research output: Contribution to journalArticle

9 Scopus citations

Lipoprotein-associated phospholipase A2 is an independent marker for coronary endothelial dysfunction in humans

Yang, E. H., McConnell, J. P., Lennon, R. J., Barsness, G. W., Pumper, G., Hartman, S. J., Rihal, C. S., Lerman, L. O. & Lerman, A., Jan 1 2006, In : Arteriosclerosis, thrombosis, and vascular biology. 26, 1, p. 106-111 6 p.

Research output: Contribution to journalArticle

97 Scopus citations

Mild renal insufficiency is associated with reduced coronary flow in patients with non-obstructive coronary artery disease

Chade, A. R., Brosh, D., Higano, S. T., Lennon, R. J., Lerman, L. O. & Lerman, A., Jan 1 2006, In : Kidney international. 69, 2, p. 266-271 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice

Napoli, C., Williams-Ignarro, S., De Nigris, F., Lerman, L. O., D'Armiento, F. P., Crimi, E., Byrns, R. E., Casamassimi, A., Lanza, A., Gombos, F., Sica, V. & Ignarro, L. J., Jul 4 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 27, p. 10479-10484 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Plasma 8-iso-prostaglandin F, a marker of oxidative stress, is increased in patients with acute myocardial infarction

Elesber, A. A., Best, P. J., Lennon, R. J., Mathew, V., Rihal, C. S., Lerman, L. O. & Lerman, A., Apr 1 2006, In : Free Radical Research. 40, 4, p. 385-391 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Prognostic value of circulating pregnancy-associated plasma protein levels in patients with chronic stable angina

Elesber, A. A., Conover, C. A., Denktas, A. E., Lennon, R. J., Holmes, D. R., Overgaard, M. T., Christiansen, M., Oxvig, C., Lerman, L. O. & Lerman, A., Jul 1 2006, In : European heart journal. 27, 14, p. 1678-1684 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Review - 3D micro CT imaging of renal micro-structural changes

Gössl, M., Bentley, M. D. & Lerman, L. O., Mar 1 2006, In : Nephron - Clinical Practice. 103, 2, p. c66-c70

Research output: Contribution to journalArticle

7 Scopus citations

Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension

Zhu, X. Y., Daghini, E., Chade, A. R., Rodriguez-Porcel, M., Napoli, C., Lerman, A. & Lerman, L. O., Aug 1 2006, In : Arteriosclerosis, thrombosis, and vascular biology. 26, 8, p. 1746-1752 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia

Chade, A. R., Zhu, X., Mushin, O. P., Napoli, C., Lerman, A. & Lerman, L. O., Aug 1 2006, In : FASEB Journal. 20, 10, p. E1014-E1023

Research output: Contribution to journalArticle

107 Scopus citations

The Porcine Remnant Kidney Model of Chronic Renal Insufficiency

Misra, S., Gordon, J. D., Fu, A. A., Glockner, J. F., Chade, A. R., Mandrekar, J., Lerman, L. & Mukhopadhyay, D., Oct 1 2006, In : Journal of Surgical Research. 135, 2, p. 370-379 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Vascular wall elasticity measurement by magnetic resonance imaging

Woodrum, D. A., Romano, A. J., Lerman, A., Pandya, U. H., Brosh, D., Rossman, P. J., Lerman, L. O. & Ehman, R. L., Sep 1 2006, In : Magnetic Resonance in Medicine. 56, 3, p. 593-600 8 p.

Research output: Contribution to journalArticle

52 Scopus citations
2007

Antioxidant vitamins induce angiogenesis in the normal pig kidney

Daghini, E., Zhu, X. Y., Versari, D., Bentley, M. D., Napoli, C., Lerman, A. & Lerman, L. O., Jul 1 2007, In : American Journal of Physiology - Renal Physiology. 293, 1, p. F371-F381

Research output: Contribution to journalArticle

26 Scopus citations

Assessment of renal hemodynamics and function in pigs with 64-section multidetector CT: Comparison with electron-beam CT

Daghini, E., Primak, A. N., Chade, A. R., Krier, J. D., Zhu, X. Y., Ritman, E. L., McCollough, C. H. & Lerman, L. O., May 1 2007, In : Radiology. 243, 2, p. 405-412 8 p.

Research output: Contribution to journalArticle

95 Scopus citations