• 22802 Citations
  • 69 Scopus h-Index
1979 …2020

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Senescent Kidney Cells in Hypertensive Patients Release Urinary Extracellular Vesicles

Santelli, A., Sun, I. O., Eirin, A., Abumoawad, A. M., Woollard, J. R., Lerman, A., Textor, SC., Puranik, A. S. & Lerman, L. O., Jun 4 2019, In : Journal of the American Heart Association. 8, 11, e012584.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

Hickson, L. T. J., Langhi Prata, L. G. P., Bobart, S. A., Evans, T. K., Giorgadze, N., Hashmi, S. K., Herrmann, S. M., Jensen, M. D., Jia, Q., Jordan, K. L., Kellogg, T. A., Khosla, S., Koerber, D. M., Lagnado, A. B., Lawson, D. K., LeBrasseur, N. K., Lerman, L. O., McDonald, K. M., McKenzie, T. J., Passos, J. F. & 13 others, Pignolo, R. J., Pirtskhalava, T., Saadiq, I. M., Schaefer, K. K., Textor, S. C., Victorelli, S. G., Volkman, T. L., Xue, A., Wentworth, M. A., Wissler Gerdes, E. O., Zhu, Y., Tchkonia, T. & Kirkland, J. L., Sep 2019, In : EBioMedicine. 47, p. 446-456 11 p.

Research output: Contribution to journalArticle

Open Access
53 Scopus citations

Sex differences in vascular and endothelial responses to acute mental stress

Martin, E. A., Tan, S. L., MacBride, L. R., Lavi, S., Lerman, L. O. & Lerman, A., Dec 1 2008, In : Clinical Autonomic Research. 18, 6, p. 339-345 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Sex-related differences in fractional flow reserve-guided treatment

Li, J., Rihal, C. S., Matsuo, Y., Elrashidi, M. Y., Flammer, A. J., Lee, M. S., Cassar, A., Lennon, R. J., Herrmann, J., Bell, M. R., Holmes, D. R., Bresnahan, J. F., Hua, Q., Lerman, L. O. & Lerman, A., Dec 1 2013, In : Circulation: Cardiovascular Interventions. 6, 6, p. 662-670 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Sex-specific genetic variants are associated with coronary endothelial dysfunction

Yoshino, S., Cilluffo, R., Prasad, M., Best, P. J. M., Atkinson, E. J., Aoki, T., Cunningham, J. M., de Andrade, M., Lerman, L. O. & Lerman, A., Apr 1 2016, In : Journal of the American Heart Association. 5, 4, e002544.

Research output: Contribution to journalArticle

20 Scopus citations

Simvastatin abates development of renal fibrosis in experimental renovascular disease

Chade, A. R., Zhu, X. Y., Grande, J. P., Krier, J. D., Lerman, A. & Lerman, L. O., Aug 2008, In : Journal of hypertension. 26, 8, p. 1651-1660 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Simvastatin decreases endothelial progenitor cell apoptosis in the kidney of hypertensive hypercholesterolemic pigs

Lavi, R., Zhu, X. Y., Chade, A. R., Lin, J., Lerman, A. & Lerman, L. O., May 1 2010, In : Arteriosclerosis, thrombosis, and vascular biology. 30, 5, p. 976-983 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Simvastatin preserves coronary endothelial function in hypercholesterolemia in the absence of lipid lowering

Wilson, S. H., Simari, R. D., Best, P. J. M., Peterson, T. E., Lerman, L. O., Aviram, M., Nath, K. A., Holmes, D. R. & Lerman, A., Jan 1 2001, In : Arteriosclerosis, thrombosis, and vascular biology. 21, 1, p. 122-128 7 p.

Research output: Contribution to journalArticle

Open Access
158 Scopus citations

Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect

Mannheim, D., Herrmann, J., Bonetti, P. O., Lavi, R., Lerman, L. O. & Lerman, A., Jun 1 2011, In : Atherosclerosis. 216, 2, p. 283-291 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
58 Scopus citations

Simvastatin preserves the structure of coronary adventitial vasa vasorum in experimental hypercholesterolemia independent of lipid lowering

Wilson, S. H., Herrmann, J., Lerman, L. O., Holmes, D. R., Napoli, C., Ritman, E. L. & Lerman, A., Jan 29 2002, In : Circulation. 105, 4, p. 415-418 4 p.

Research output: Contribution to journalArticle

204 Scopus citations

Simvastatin prevents coronary microvascular remodeling in renovascular hypertensive pigs

Zhu, X. Y., Daghini, E., Chade, A. R., Napoli, C., Ritman, E. L., Lerman, A. & Lerman, L. O., Apr 1 2007, In : Journal of the American Society of Nephrology. 18, 4, p. 1209-1217 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia

Chade, A. R., Zhu, X., Mushin, O. P., Napoli, C., Lerman, A. & Lerman, L. O., Aug 1 2006, In : FASEB Journal. 20, 10, p. E1014-E1023

Research output: Contribution to journalArticle

108 Scopus citations

Single-nephron glomerular filtration rate in healthy adults

Denic, A., Mathew, J., Lerman, L. O., Lieske, J. C., Larson, J. J., Alexander, M. P., Poggio, E., Glassock, R. J. & Rule, A. D., Jun 15 2017, In : New England Journal of Medicine. 376, 24, p. 2349-2357 9 p.

Research output: Contribution to journalArticle

79 Scopus citations

Single nucleotide polymorphisms associated with abnormal coronary microvascular function

Yoshino, S., Cilluffo, R., Best, P. J. M., Atkinson, E. J., Aoki, T., Cunningham, J. M., De Andrade, M., Choi, B. J., Lerman, L. O. & Lerman, A., Jun 2014, In : Coronary Artery Disease. 25, 4, p. 281-289 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Smoking is associated with epicardial coronary endothelial dysfunction and elevated white blood cell count in patients with chest pain and early coronary artery disease

Lavi, S., Prasad, A., Yang, E. H., Mathew, V., Simari, R. D., Rihal, C. S., Lerman, L. O. & Lerman, A., May 1 2007, In : Circulation. 115, 20, p. 2621-2627 7 p.

Research output: Contribution to journalArticle

96 Scopus citations
54 Scopus citations

Targeted Imaging of Renal Fibrosis Using Antibody-Conjugated Gold Nanoparticles in Renal Artery Stenosis

Zhu, X. Y., Zou, X., Mukherjee, R., Yu, Z., Ferguson, C. M., Zhou, W., McCollough, C. H. & Lerman, L. O., Oct 1 2018, In : Investigative Radiology. 53, 10, p. 623-628 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Targeting Murine Mesenchymal Stem Cells to Kidney Injury Molecule-1 Improves Their Therapeutic Efficacy in Chronic Ischemic Kidney Injury

Zou, X., Jiang, K., Puranik, A. S., Jordan, K. L., Tang, H., Zhu, X. & Lerman, L. O., May 2018, In : Stem Cells Translational Medicine. 7, 5, p. 394-403 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia

Suvakov, S., Cubro, H., White, W. M., Butler Tobah, Y. S., Weissgerber, T. L., Jordan, K. L., Zhu, X. Y., Woollard, J. R., Chebib, F. T., Milic, N. M., Grande, J. P., Xu, M., Tchkonia, T., Kirkland, J. L., Lerman, L. O. & Garovic, V. D., Sep 14 2019, In : Biology of Sex Differences. 10, 1, 49.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Temporal analysis of signaling pathways activated in a murine model of two-kidney, one-clip hypertension

Cheng, J., Zhou, W., Warner, G. M., Knudsen, B. E., Garovic, V. D., Gray, C. E., Lerman, L. O., Platt, J. L., Romero, J. C., Textor, S. C., Nath, K. A. & Grande, J. P., Oct 2009, In : American Journal of Physiology - Renal Physiology. 297, 4, p. F1055-F1068

Research output: Contribution to journalArticle

47 Scopus citations

TGF expression and macrophage accumulation in atherosclerotic renal artery stenosis

Gloviczki, M. L., Keddis, M. T., Garovic, V. D., Friedman, H., Herrmann, S., McKusick, M. A., Misra, S., Grande, J. P., Lerman, L. O. & Textor, S. C., Apr 5 2013, In : Clinical Journal of the American Society of Nephrology. 8, 4, p. 546-553 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

The association between circulating MicroRNA levels and coronary endothelial function

Widmer, R. J., Chung, W. Y., Herrmann, J., Jordan, K. L., Lerman, L. O. & Lerman, A., Oct 13 2014, In : PloS one. 9, 10, e109650.

Research output: Contribution to journalArticle

19 Scopus citations

The association between renal atherosclerotic plaque characteristics and renal function before and after renal artery intervention

Takumi, T., Mathew, V., Barsness, G. W., Kataoka, T., Rubinshtein, R., Rihal, C. S., Gulati, R., Eeckhout, E., Lennon, R. J., Lerman, L. O. & Lerman, A., Dec 2011, In : Mayo Clinic proceedings. 86, 12, p. 1165-1172 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

The chemokine monocyte chemoattractant protein-1 contributes to renal dysfunction in swine renovascular hypertension

Zhu, X. Y., Chade, A. R., Krier, J. D., Daghini, E., Lavi, R., Guglielmotti, A., Lerman, A. & Lerman, L. O., Jan 1 2009, In : Journal of hypertension. 27, 10, p. 2063-2073 11 p.

Research output: Contribution to journalArticle

55 Scopus citations

The effect of a low–osmolar radiographic contrast medium on in vivo and postmortem renal size

Lerman, L. O., Bentley, M. D., Bell, M. R., Rumberger, J. A., Sheedy, P. F. & Romero, J. C., Nov 1991, In : Investigative radiology. 26, 11, p. 992-997 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function

Corban, M. T., Widmer, R. J., Cilluffo, R., Kazeck, M. A., Lennon, R. J., Lerman, L. O. & Lerman, A., Jan 1 2020, (Accepted/In press) In : European Journal of Nutrition.

Research output: Contribution to journalArticle

The Hyperactive Lesion, beyond Anatomy

Sara, J. D., Lerman, L. O. & Lerman, A., Sep 8 2015, In : Journal of the American College of Cardiology. 66, 10, p. 1116-1118 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

The interaction between coronary endothelial dysfunction, local oxidative stress, and endogenous nitric oxide in humans

Lavi, S., Yang, E. H., Prasad, A., Mathew, V., Barsness, G. W., Rihal, C. S., Lerman, L. O. & Lerman, A., Jan 1 2008, In : Hypertension. 51, 1, p. 127-133 7 p.

Research output: Contribution to journalArticle

100 Scopus citations

The long-term effect of coronary stenting on epicardial and microvascular endothelial function

Lim, S. H., Flammer, A. J., Yoon, M. H., Lennon, R. J., Gulati, R., Mathew, V., Rihal, C. S., Lerman, L. O. & Lerman, A., Aug 1 2012, In : Circulation: Cardiovascular Interventions. 5, 4, p. 523-529 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

The metabolic syndrome alters the miRNA signature of porcine adipose tissue-derived mesenchymal stem cells

Meng, Y., Eirin, A., Zhu, X. Y., Tang, H., Chanana, P., Lerman, A., van Wijnen, A. J. & Lerman, L. O., 2017, (Accepted/In press) In : Cytometry Part A.

Research output: Contribution to journalArticle

19 Scopus citations

The metabolic syndrome and chronic kidney disease

Zhang, X. & Lerman, L. O., Sep 7 2016, (Accepted/In press) In : Translational Research.

Research output: Contribution to journalArticle

23 Scopus citations

The Metabolic Syndrome Does Not Affect Development of Collateral Circulation in the Poststenotic Swine Kidney

Zhang, X., Kim, S. R., Ferguson, C. M., Ebrahimi, B., Hedayat, A. F., Lerman, A. & Lerman, L. O., Nov 13 2018, In : American Journal of Hypertension. 31, 12, p. 1307-1316 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

The metabolic syndrome induces early changes in the swine renal medullary mitochondria

Eirin, A., Woollard, J. R., Ferguson, C. M., Jordan, K. L., Tang, H., Textor, S. C., Lerman, A. & Lerman, L. O., Jun 1 2017, In : Translational Research. 184, p. 45-56.e9

Research output: Contribution to journalArticle

17 Scopus citations

The metabolic syndrome modifies the mRNA expression profile of extracellular vesicles derived from porcine mesenchymal stem cells

Meng, Y., Eirin, A., Zhu, X. Y., O'Brien, D. R., Lerman, A., Van Wijnen, A. J. & Lerman, L. O., Jul 21 2018, In : Diabetology and Metabolic Syndrome. 10, 1, 58.

Research output: Contribution to journalArticle

10 Scopus citations

The Porcine Remnant Kidney Model of Chronic Renal Insufficiency

Misra, S., Gordon, J. D., Fu, A. A., Glockner, J. F., Chade, A. R., Mandrekar, J., Lerman, L. & Mukhopadhyay, D., Oct 1 2006, In : Journal of Surgical Research. 135, 2, p. 370-379 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Therapeutic effects of autologous bone marrow cells and metabolic intervention in the ischemic hindlimb of spontaneously hypertensive rats involve reduced cell senescence and CXCR4/Akt/eNOS Pathways

Nigris, F. D., Balestrieri, M. L., Williams-Ignarro, S., D'Armiento, F. P., Lerman, L. O., Byrns, R., Crimi, E., Palagiano, A., Fatigati, G., Ignarro, L. J. & Napoli, C., Oct 1 2007, In : Journal of Cardiovascular Pharmacology. 50, 4, p. 424-433 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Therapeutic effects of concurrent autologous bone marrow cell infusion and metabolic intervention in ischemia-induced angiogenesis in the hypercholesterolemic mouse hindlimb

de Nigris, F., Williams-Ignarro, S., Sica, V., D'Armiento, F. P., Lerman, L. O., Byrns, R. E., Sica, G., Fiorito, C., Ignarro, L. J. & Napoli, C., Apr 25 2007, In : International Journal of Cardiology. 117, 2, p. 238-243 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

The relationship between renal cortical volume and predisposition to hypertension

Flickinger, A. L., Lerman, L. O., Sheedy, P. F. & Turner, S. T., Aug 1996, In : American journal of hypertension. 9, 8 I, p. 779-786 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
86 Scopus citations

The use of magnetic resonance to evaluate tissue oxygenation in renal artery stenosis

Textor, S. C., Glockner, J. F., Lerman, L. O., Misra, S., McKusick, M. A., Riederer, S. J., Grande, J. P., Gomez, S. I. & Romero, J. C., Apr 2008, In : Journal of the American Society of Nephrology. 19, 4, p. 780-788 9 p.

Research output: Contribution to journalArticle

123 Scopus citations

The vasa vasorum in atherosclerosis: The vessel within the vascular wall

Kwon, T. G., Lerman, L. O. & Lerman, A., Jun 16 2015, In : Journal of the American College of Cardiology. 65, 23, p. 2478-2480 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Tissue hypoxia, inflammation, and loss of glomerular filtration rate in human atherosclerotic renovascular disease

Abumoawad, A., Saad, A., Ferguson, C. M., Eirin, A., Woollard, J. R., Herrmann, S. M., Hickson, L. T. J., Bendel, E. C., Misra, S., Glockner, J., Lerman, L. O. & Textor, S. C., Apr 2019, In : Kidney international. 95, 4, p. 948-957 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Transition from obesity to metabolic syndrome is associated with altered myocardial autophagy and apoptosis

Li, Z. L., Woollard, J. R., Ebrahimi, B., Crane, J. A., Jordan, K. L., Lerman, A., Wang, S. M. & Lerman, L. O., May 1 2012, In : Arteriosclerosis, thrombosis, and vascular biology. 32, 5, p. 1132-1141 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

Transplanted senescent renal scattered tubular-like cells induce injury in the mouse kidney

Kim, S. R., Jiang, K., Ferguson, C. M., Tang, H., Chen, X., Zhu, X. Y., Hickson, L. T. J., Tchkonia, T., Kirkland, J. L. & Lerman, L. O., May 2020, In : American Journal of Physiology - Renal Physiology. 318, 5, p. F1167-F1176

Research output: Contribution to journalArticle

Treating coronary disease and the impact of endothelial dysfunction

Matsuzawa, Y., Guddeti, R. R., Kwon, T. G., Lerman, L. O. & Lerman, A., Mar 1 2015, In : Progress in Cardiovascular Diseases. 57, 5, p. 431-442 12 p.

Research output: Contribution to journalArticle

33 Scopus citations
Open Access
2 Scopus citations

Trimetazidine reduces early and long-term effects of experimental renal warm ischemia: A dose effect study

Cau, J., Favreau, F., Tillement, J. P., Lerman, L. O., Hauet, T. & Goujon, J. M., Apr 2008, In : Journal of vascular surgery. 47, 4, p. 852-860.e4

Research output: Contribution to journalArticle

20 Scopus citations

Tubulointerstitial Fibrosis of Living Donor Kidneys Associates with Urinary Monocyte Chemoattractant Protein 1

Wang, X., Lieske, J. C., Alexander, M. P., Jayachandran, M., Denic, A., Mathew, J., Lerman, L. O., Kremers, W. K., Larson, J. J. & Rule, A. D., Jul 1 2016, In : American journal of nephrology. 43, 6, p. 454-459 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ultrasound-guided placement of a renal artery stent using an intracardiac probe for transvascular imaging

Belohlavek, M., Jiamsripong, P., Mcmahon, E. M., Lombari, T. R. & Lerman, L. O., 2011, In : Open Cardiovascular Medicine Journal. 5, 1, p. 215-217 3 p.

Research output: Contribution to journalArticle

1 Scopus citations