Lifeng Yu, PhD

  • 5503 Citations
  • 40 Scopus h-Index
20022019
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Research Output 2002 2019

  • 5503 Citations
  • 40 Scopus h-Index
  • 151 Article
  • 58 Conference contribution
  • 1 Letter
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Article
2019
1 Citation (Scopus)

A deep learning- and partial least square regression-based model observer for a low-contrast lesion detection task in CT

Gong, H., Yu, L., Leng, S., Dilger, S. K., Ren, L., Zhou, W., Fletcher, J. G. & McCollough, C. H., Jan 1 2019, In : Medical physics.

Research output: Contribution to journalArticle

Least-Squares Analysis
Learning
Noise
Liver
Radiation

Clinical assessment of metal artifact reduction methods in dual-energy CT examinations of instrumented spines

Long, Z., De Lone, D. R., Kotsenas, A. L., Lehman, V. T., Nagelschneider, A. A., Michalak, G. J., Fletcher, J. G., McCollough, C. H. & Yu, L., Feb 1 2019, In : American Journal of Roentgenology. 212, 2, p. 395-401 7 p.

Research output: Contribution to journalArticle

Artifacts
Spine
Metals
Bone and Bones

Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study

Dilger, S. K. N., Nelson, N., Venkatesh, S. K., Ehman, E., Fidler, J. L., Fletcher, J. G., McCollough, C. H. & Yu, L., Sep 1 2019, In : Investigative radiology. 54, 9, p. 572-579 8 p.

Research output: Contribution to journalArticle

Cholangiography
Contrast Media
Noise
Magnetic Resonance Spectroscopy
Tomography

Impact of prior information on material decomposition in dual- and multienergy computed tomography

Ren, L., Tao, S., Rajendran, K., McCollough, C. H. & Yu, L., Jan 1 2019, In : Journal of Medical Imaging. 6, 1, 013503.

Research output: Contribution to journalArticle

Tomography
Iodine
Noise
Water
Gadolinium
1 Citation (Scopus)

Lead shielding in pediatric chest CT: Effect of apron placement outside the scan volume on radiation dose reduction

Yu, L., Bruesewitz, M. R., Vrieze, T. J. & McCollough, C. H., Jan 1 2019, In : American Journal of Roentgenology. 212, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

Thorax
Radiation
Pediatrics
Pelvis
Abdomen
1 Citation (Scopus)
Liver
Water
Noise
Computer-Assisted Image Processing
ROC Curve
Theoretical Models
Liver
Water
Task Performance and Analysis
ROC Curve

Technical Note: Increased photon starvation artifacts at low helical pitch in ultra-low-dose CT

Browne, J. E., Bruesewitz, M. R., Vrieze, T. J., McCollough, C. H. & Yu, L., Jan 1 2019, (Accepted/In press) In : Medical physics.

Research output: Contribution to journalArticle

Starvation
Photons
Artifacts
Delivery of Health Care
Noise
2018
1 Citation (Scopus)

Breathe New Life Into Your Chest CT Exams: Using Advanced Acquisition and Postprocessing Techniques

Weber, N. M., Koo, C. W., Yu, L., Bartholmai, B. J., Halaweish, A. F., McCollough, C. H. & Fletcher, J. G., Jan 1 2018, (Accepted/In press) In : Current Problems in Diagnostic Radiology.

Research output: Contribution to journalArticle

Thorax
Tomography
Artifacts
Lung Diseases
X-Rays

Correction to: Chest computed tomography angiography in children on extracorporeal membrane oxygenation (ECMO)

Hull, N. C., Schooler, G. R., Binkovitz, L. A., Williamson, E. E., Araoz, P. A., Yu, L. & Young, P. M., Jan 3 2018, (Accepted/In press) In : Pediatric Radiology. 1 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Emotions
Thorax
Computed Tomography Angiography
6 Citations (Scopus)

Dual-source multienergy CT with triple or quadruple x-ray beams

Yu, L., Ren, L., Li, Z., Leng, S. & McCollough, C. H., Jul 1 2018, In : Journal of Medical Imaging. 5, 3, 033502.

Research output: Contribution to journalArticle

Photons
X-Rays
Contrast Media
Computer Simulation
Noise
5 Citations (Scopus)

Evaluation of cross-sectional and longitudinal changes in volumetric bone mineral density in postmenopausal women using single- versus dual-energy quantitative computed tomography

Sfeir, J. G., Drake, M. M., Atkinson, E. J., Achenbach, S. J., Camp, J. J., Tweed, A. J., McCready, L. K., Yu, L., Adkins, M. C., Amin, S. & Khosla, S., Jul 1 2018, In : Bone. 112, p. 145-152 8 p.

Research output: Contribution to journalArticle

Bone Density
Bone Marrow
Tomography
Fats
Bone and Bones
2 Citations (Scopus)

Evaluation of projection- and dual-energy-based methods for metal artifact reduction in CT using a phantom study

Long, Z., Bruesewitz, M. R., Delone, D. R., Morris, J. M., Amrami, K. K., Adkins, M. C., Glazebrook, K. N., Kofler, J. M., Leng, S., McCollough, C. H., Fletcher, J. G., Halaweish, A. F. & Yu, L., Jan 1 2018, (Accepted/In press) In : Journal of Applied Clinical Medical Physics.

Research output: Contribution to journalArticle

Artifacts
artifacts
projection
Metals
evaluation
2 Citations (Scopus)

Inter-laboratory comparison of channelized hotelling observer computation

Ba, A., Abbey, C. K., Baek, J., Han, M., Bouwman, R. W., Balta, C., Brankov, J., Massanes, F., Gifford, H. C., Hernandez-Giron, I., Veldkamp, W. J. H., Petrov, D., Marshall, N., Samuelson, F. W., Zeng, R., Solomon, J. B., Samei, E., Timberg, P., Förnvik, H., Reiser, I. & 3 others, Yu, L., Gong, H. & Bochud, F. O., Jul 1 2018, In : Medical Physics. 45, 7, p. 3019-3030 12 p.

Research output: Contribution to journalArticle

Uncertainty
Task Performance and Analysis
Diagnostic Imaging
Water
4 Citations (Scopus)

Observer performance with varying radiation dose and reconstruction methods for detection of hepatic metastases

Fletcher, J. G., Fidler, J. L., Venkatesh, S. K., Hough, D. M., Takahashi, N. M., Yu, L., Johnson, M., Leng, S., Holmes III, D. R., Carter, R. E. & McCollough, C. H., Nov 1 2018, In : Radiology. 289, 2, p. 455-464 10 p.

Research output: Contribution to journalArticle

Radiation
Neoplasm Metastasis
Liver
ROC Curve
Cone-Beam Computed Tomography
2017
9 Citations (Scopus)

An effective noise reduction method for multi-energy CT images that exploit spatio-spectral features

Li, Z., Leng, S., Yu, L., Manduca, A. & McCollough, C. H., May 1 2017, In : Medical Physics. 44, 5, p. 1610-1623 14 p.

Research output: Contribution to journalArticle

Noise
Cadaver
Radiology
Swine
Head

Chest computed tomography angiography in children on extracorporeal membrane oxygenation (ECMO)

Hull, N. C., Schooler, G. R., Binkovitz, L. A., Williamson, E. E., Araoz, P. A., Yu, L. & Young, P. M., Dec 7 2017, (Accepted/In press) In : Pediatric Radiology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Thorax
Pediatrics
Anatomy
Communication
12 Citations (Scopus)

Correlation between a 2D channelized Hotelling observer and human observers in a low-contrast detection task with multislice reading in CT

Yu, L., Chen, B., Kofler, J. M., Favazza, C. P., Leng, S., Kupinski, M. A. & McCollough, C. H., Aug 1 2017, In : Medical Physics. 44, 8, p. 3990-3999 10 p.

Research output: Contribution to journalArticle

Reading
Confidence Intervals
Radiation
10 Citations (Scopus)

Estimating patient dose from CT exams that use automatic exposure control: Development and validation of methods to accurately estimate tube current values

Mcmillan, K., Bostani, M., Cagnon, C. H., Yu, L., Leng, S., McCollough, C. H. & Mcnitt-Gray, M. F., 2017, (Accepted/In press) In : Medical Physics.

Research output: Contribution to journalArticle

Pelvis
Abdomen
Thorax
Breast
Spleen

Evaluation of a projection-domain lung nodule insertion technique in thoracic computed tomography

Ma, C., Yu, L., Chen, B., Koo, C. W., Takahashi, E. A., Fletcher, J. G., Levin, D. L., Kuzo, R. S., Viers, L. D., Vincent-Sheldon, S. A., Leng, S. & McCollough, C. H., Jan 1 2017, In : Journal of Medical Imaging. 4, 1, 013510.

Research output: Contribution to journalArticle

Tomography
Thorax
Confidence Intervals
Lung
Image quality
5 Citations (Scopus)

Low-dose CT for craniosynostosis: Preserving diagnostic benefit with substantial radiation dose reduction

Montoya, J. C., Eckel, L. J., DeLone, D. R., Kotsenas, A. L., Diehn, F. E., Yu, L., Bartley, A. C., Carter, R. E., McCollough, C. H. & Fletcher, J. G., Apr 1 2017, In : American Journal of Neuroradiology. 38, 4, p. 672-677 6 p.

Research output: Contribution to journalArticle

Craniosynostoses
Radiation
Pediatrics
Sutures
Head
17 Citations (Scopus)

Low-dose CT for the detection and classification of metastatic liver lesions: Results of the 2016 Low Dose CT Grand Challenge

McCollough, C. H., Bartley, A. C., Carter, R. E., Chen, B., Drees, T. A., Edwards, P., Holmes III, D. R., Huang, A. E., Khan, F., Leng, S., McMillan, K. L., Michalak, G. J., Nunez, K. M., Yu, L. & Fletcher, J. G., Oct 1 2017, In : Medical Physics. 44, 10, p. e339-e352

Research output: Contribution to journalArticle

Liver
Neoplasm Metastasis
Noise
ROC Curve
Information Dissemination
5 Citations (Scopus)

Low kV versus dual-energy virtual monoenergetic CT imaging for proven liver lesions: what are the advantages and trade-offs in conspicuity and image quality? A pilot study

Hanson, G. J., Michalak, G. J., Childs, R., McCollough, B., Kurup, A. N., Hough, D. M., Frye, J. M., Fidler, J. L., Venkatesh, S. K., Leng, S., Yu, L., Halaweish, A. F., Harmsen, W. S., McCollough, C. H. & Fletcher, J. G., Oct 5 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Noise
Artifacts
Liver
Iodine
Radiologists
3 Citations (Scopus)

Selection of optimal tube potential settings for dual-energy CT virtual mono-energetic imaging of iodine in the abdomen

Michalak, G., Grimes, J., Fletcher, J. G., Halaweish, A., Yu, L., Leng, S. & McCollough, C. H., Apr 1 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-8 8 p.

Research output: Contribution to journalArticle

Photons
Iodine
Abdomen
Water
Information Systems
20 Citations (Scopus)

Spectral performance of a whole-body research photon counting detector CT: Quantitative accuracy in derived image sets

Leng, S., Zhou, W., Yu, Z., Halaweish, A., Krauss, B., Schmidt, B., Yu, L., Kappler, S. & McCollough, C. H., Aug 21 2017, In : Physics in Medicine and Biology. 62, 17, p. 7216-7232 17 p.

Research output: Contribution to journalArticle

Photons
Iodine
X-Ray Computed Tomography Scanners
Research
Tomography
1 Citation (Scopus)

Technical Note: Insertion of digital lesions in the projection domain for dual-source, dual-energy CT

Ferrero, A., Chen, B., Li, Z., Yu, L. & McCollough, C. H., May 1 2017, In : Medical Physics. 44, 5, p. 1655-1660 6 p.

Research output: Contribution to journalArticle

Kidney Calculi
X-Rays
Minerals
Calcium
Iodine
2 Citations (Scopus)
Pelvis
Abdomen
CT protocol
2016
6 Citations (Scopus)

A robust noise reduction technique for time resolved CT

Li, Z., Yu, L., Leng, S., Williamson, E. E., Kotsenas, A. L., DeLone, D. R., Manduca, A. & McCollough, C. H., Jan 1 2016, In : Medical Physics. 43, 1, p. 347-359 13 p.

Research output: Contribution to journalArticle

Noise
Perfusion
Brain
Four-Dimensional Computed Tomography
15 Citations (Scopus)

Construction of realistic phantoms from patient images and a commercial three-dimensional printer

Leng, S., Chen, B., Vrieze, T., Kuhlmann, J., Yu, L., Alexander, A., Matsumoto, J., Morris, J. & McCollough, C. H., Jul 1 2016, In : Journal of Medical Imaging. 3, 3, 033501.

Research output: Contribution to journalArticle

Tomography
Liver
Printing
Cerebrospinal fluid
Cerebrospinal Fluid
9 Citations (Scopus)

Dealing with uncertainty in CT images

Fletcher, J. G., Leng, S., Yu, L. & McCollough, C. H., Apr 1 2016, In : Radiology. 279, 1, p. 5-10 6 p.

Research output: Contribution to journalArticle

X Ray Computed Tomography
Uncertainty
7 Citations (Scopus)

Estimation of Observer Performance for Reduced Radiation Dose Levels in CT. Eliminating Reduced Dose Levels That Are Too Low Is the First Step

Fletcher, J. G., Yu, L., Fidler, J. L., Levin, D. L., DeLone, D. R., Hough, D. M., Takahashi, N., Venkatesh, S. K., Sykes, A-M. G., White, D., Lindell, R. M., Kotsenas, A. L., Campeau, N. G., Lehman, V. T., Bartley, A. C., Leng, S., Holmes III, D. R., Toledano, A. Y., Carter, R. E. & McCollough, C. H., Aug 30 2016, (Accepted/In press) In : Academic Radiology.

Research output: Contribution to journalArticle

Tomography
Radiation
Head
ROC Curve
Thorax
90 Citations (Scopus)

Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array

Yu, Z., Leng, S., Jorgensen, S. M., Li, Z., Gutjahr, R., Chen, B., Halaweish, A. F., Kappler, S., Yu, L., Ritman, E. L. & McCollough, C. H., Feb 2 2016, In : Physics in Medicine and Biology. 61, 4, p. 1572-1595 24 p., 1572.

Research output: Contribution to journalArticle

Photons
Research
Noise
Whole-Body Counting
X-Rays
68 Citations (Scopus)

Human Imaging With Photon Counting–Based Computed Tomography at Clinical Dose Levels: Contrast-to-Noise Ratio and Cadaver Studies

Gutjahr, R., Halaweish, A. F., Yu, Z., Leng, S., Yu, L., Li, Z., Jorgensen, S. M., Ritman, E. L., Kappler, S. & McCollough, C. H., Jan 25 2016, (Accepted/In press) In : Investigative Radiology.

Research output: Contribution to journalArticle

Photons
Cadaver
Noise
Tomography
X-Ray Computed Tomography Scanners
8 Citations (Scopus)

Impact of number of repeated scans on model observer performance for a low-contrast detection task in computed tomography

Ma, C., Yu, L., Chen, B., Favazza, C., Leng, S. & McCollough, C. H., Apr 1 2016, In : Journal of Medical Imaging. 3, 2, 023504.

Research output: Contribution to journalArticle

Tomography
X-Ray Computed Tomography Scanners
ROC Curve
Research Design
Radiation
3 Citations (Scopus)

Pediatric thoracic CT angiography at 70 kV: a phantom study to investigate the effects on image quality and radiation dose

MacDougall, R. D., Kleinman, P. L., Yu, L. & Lee, E. Y., Mar 17 2016, (Accepted/In press) In : Pediatric Radiology. p. 1-6 6 p.

Research output: Contribution to journalArticle

Noise
Thorax
Radiation
Pediatrics
Iodine
12 Citations (Scopus)

Technical Note: Improved CT number stability across patient size using dual-energy CT virtual monoenergetic imaging

Michalak, G., Grimes, J., Fletcher, J. G., Halaweish, A., Yu, L., Leng, S. & McCollough, C. H., Jan 1 2016, In : Medical Physics. 43, 1, p. 513-517 5 p.

Research output: Contribution to journalArticle

Water
Artifacts
Tomography
Tin
Datasets
1 Citation (Scopus)

Technical Note: Display window setting: An important factor for detecting subtle but clinically relevant artifacts in daily CT quality control

Long, Z., Bruesewitz, M. R., Sheedy, E. N., Powell, M. A., Kramer, J. C., Supalla, R. R., Colvin, C. M., Bechel, J. R., Favazza, C. P., Kofler, J. M., Leng, S., McCollough, C. H. & Yu, L., Dec 1 2016, In : Medical Physics. 43, 12, 4966698.

Research output: Contribution to journalArticle

Quality Control
Artifacts
Tomography
Area Under Curve
Radiology
2 Citations (Scopus)

Validation of a Projection-domain Insertion of Liver Lesions into CT Images

Chen, B., Ma, C., Leng, S., Fidler, J. L., Sheedy, S. P., McCollough, C. H., Fletcher, J. G. & Yu, L., Oct 1 2016, In : Academic Radiology. 23, 10, p. 1221-1229 9 p.

Research output: Contribution to journalArticle

Liver
ROC Curve
Area Under Curve
Tomography
Clinical Trials
2015
3 Citations (Scopus)

A cross-platform survey of CT image quality and dose from routine abdomen protocols and a method to systematically standardize image quality

Favazza, C. P., Duan, X., Zhang, Y., Yu, L., Leng, S., Kofler, J. M., Bruesewitz, M. R. & McCollough, C. H., Oct 13 2015, In : Physics in Medicine and Biology. 60, 21, p. 8381-8397 17 p.

Research output: Contribution to journalArticle

Abdomen
Benchmarking
Noise
Radiation
Health
5 Citations (Scopus)
Accreditation
Radiology
Noise
11 Citations (Scopus)
Noise
Tomography
25 Citations (Scopus)
Urinary Calculi
Apatites
Area Under Curve
Oxalates
Uric Acid
45 Citations (Scopus)

Degradation of CT low-contrast spatial resolution due to the use of iterative reconstruction and reduced dose levels

McCollough, C. H., Yu, L., Kofler, J. M., Leng, S., Zhang, Y., Li, Z. & Carter, R. E., Aug 1 2015, In : Radiology. 276, 2, p. 499-506 8 p.

Research output: Contribution to journalArticle

Accreditation
Radiology
Cone-Beam Computed Tomography
Radiation
367 Citations (Scopus)

Dual- and multi-energy CT: Principles, technical approaches, and clinical applications

McCollough, C. H., Leng, S., Yu, L. & Fletcher, J. G., Sep 1 2015, In : Radiology. 276, 3, p. 637-653 17 p.

Research output: Contribution to journalArticle

Tomography
X-Rays
Photons
Contrast Media
4 Citations (Scopus)
Radiology
Thorax
Water
7 Citations (Scopus)

Lesion insertion in the projection domain: Methods and initial results

Chen, B., Leng, S., Yu, L., Yu, Z., Ma, C. & McCollough, C. H., Dec 1 2015, In : Medical Physics. 42, 12, 4935530.

Research output: Contribution to journalArticle

Liver
Radiologists
50 Citations (Scopus)
Iodine
Noise
Tomography
X-Ray Computed Tomography Scanners
Health Insurance Portability and Accountability Act
9 Citations (Scopus)

Observer performance for adaptive, image-based denoising and filtered back projection compared to scanner-based iterative reconstruction for lower dose CT enterography

Fletcher, J. G., Hara, A. K., Fidler, J. L., Silva, A. C., Barlow, J. M., Carter, R. E., Bartley, A., Shiung, M., Holmes III, D. R., Weber, N. K., Bruining, D. H., Yu, L. & McCollough, C. H., Mar 1 2015, (Accepted/In press) In : Abdominal Imaging.

Research output: Contribution to journalArticle

Noise
Inflammation
Gastroenterology
Reading
Confidence Intervals
28 Citations (Scopus)

Observer performance in the detection and classification of malignant hepatic nodules and masses with CT image-space denoising and iterative reconstruction

Fletcher, J. G., Yu, L., Li, Z., Manduca, A., Blezek, D. J., Hough, D. M., Venkatesh, S. K., Brickner, G. C., Cernigliaro, J. C., Hara, A. K., Fidler, J. L., Lake, D. S., Shiung, M., Lewis, D., Leng, S., Augustine, K. E., Carter, R. E., Holmes III, D. R. & McCollough, C. H., Aug 1 2015, In : Radiology. 276, 2, p. 465-478 14 p.

Research output: Contribution to journalArticle

Liver
Confidence Intervals
Pancreas
Noise
Health Insurance Portability and Accountability Act
7 Citations (Scopus)

Radiation dose reduction in dual-energy CT: Does it affect the accuracy of urinary stone characterization?

Qu, M., Yu, L., Cardona, D. G., Liu, Y., Duan, X., Ai, S., Leng, S., Shiung, M. & McCollough, C. H., Aug 1 2015, In : American Journal of Roentgenology. 205, 2, p. W172-W176

Research output: Contribution to journalArticle

Urinary Calculi
Uric Acid
Radiation
Noise
Sensitivity and Specificity