Lifeng Yu, PhD

  • 5862 Citations
  • 40 Scopus h-Index
20022020

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2020

A Universal Protocol for Abdominal CT Examinations Performed on a Photon-Counting Detector CT System: A Feasibility Study

Zhou, W., Michalak, G. J., Weaver, J. M., Gong, H., Yu, L., McCollough, C. H. & Leng, S., Apr 1 2020, In : Investigative radiology. 55, 4, p. 226-232 7 p.

Research output: Contribution to journalArticle

Image quality in abdominal CT using an iodine contrast reduction algorithm employing patient size and weight and low kV CT technique

Iyer, V. R., Ehman, E. C., Khandelwal, A., Wells, M. L., Lee, Y. S., Weber, N. M., Johnson, M. P., Yu, L., McCollough, C. H. & Fletcher, J. G., Jan 1 2020, (Accepted/In press) In : Acta Radiologica.

Research output: Contribution to journalArticle

Synthesizing images from multiple kernels using a deep convolutional neural network

Missert, A. D., Yu, L., Leng, S., Fletcher, J. G. & McCollough, C. H., Feb 1 2020, In : Medical physics. 47, 2, p. 422-430 9 p.

Research output: Contribution to journalArticle

2019

A deep learning- and partial least square regression-based model observer for a low-contrast lesion detection task in CT

Gong, H., Yu, L., Leng, S., Dilger, S. K., Ren, L., Zhou, W., Fletcher, J. G. & McCollough, C. H., May 2019, In : Medical physics. 46, 5, p. 2052-2063 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Clinical assessment of metal artifact reduction methods in dual-energy CT examinations of instrumented spines

Long, Z., De Lone, D. R., Kotsenas, A. L., Lehman, V. T., Nagelschneider, A. A., Michalak, G. J., Fletcher, J. G., McCollough, C. H. & Yu, L., Feb 1 2019, In : American Journal of Roentgenology. 212, 2, p. 395-401 7 p.

Research output: Contribution to journalArticle

Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study

Dilger, S. K. N., Nelson, N., Venkatesh, S. K., Ehman, E., Fidler, J. L., Fletcher, J. G., McCollough, C. H. & Yu, L., Sep 1 2019, In : Investigative radiology. 54, 9, p. 572-579 8 p.

Research output: Contribution to journalArticle

Impact of prior information on material decomposition in dual- and multienergy computed tomography

Ren, L., Tao, S., Rajendran, K., McCollough, C. H. & Yu, L., Jan 1 2019, In : Journal of Medical Imaging. 6, 1, 013503.

Research output: Contribution to journalArticle

2 Scopus citations

Lead shielding in pediatric chest CT: Effect of apron placement outside the scan volume on radiation dose reduction

Yu, L., Bruesewitz, M. R., Vrieze, T. J. & McCollough, C. H., Jan 1 2019, In : American Journal of Roentgenology. 212, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2 Scopus citations

Quantitative accuracy and dose efficiency of dual-contrast imaging using dual-energy CT: a phantom study

Ren, L., Rajendran, K., McCollough, C. H. & Yu, L., Jan 1 2019, (Accepted/In press) In : Medical physics.

Research output: Contribution to journalArticle

1 Scopus citations

Radiation dose efficiency of multi-energy photon-counting-detector CT for dual-contrast imaging

Ren, L., Rajendran, K., McCollough, C. H. & Yu, L., Dec 13 2019, In : Physics in medicine and biology. 64, 24, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

State of the art in abdominal CT: The limits of iterative reconstruction algorithms

Mileto, A., Guimaraes, L. S., McCollough, C. H., Fletcher, J. G. & Yu, L., Jan 1 2019, In : Radiology. 293, 3, p. 491-503 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Technical Note: Increased photon starvation artifacts at low helical pitch in ultra-low-dose CT

Browne, J. E., Bruesewitz, M. R., Vrieze, T. J., McCollough, C. H. & Yu, L., Dec 1 2019, In : Medical physics. 46, 12, p. 5538-5543 6 p.

Research output: Contribution to journalArticle

2018

Breathe New Life Into Your Chest CT Exams: Using Advanced Acquisition and Postprocessing Techniques

Weber, N. M., Koo, C. W., Yu, L., Bartholmai, B. J., Halaweish, A. F., McCollough, C. H. & Fletcher, J. G., Jan 1 2018, (Accepted/In press) In : Current Problems in Diagnostic Radiology.

Research output: Contribution to journalArticle

1 Scopus citations

Correction to: Chest computed tomography angiography in children on extracorporeal membrane oxygenation (ECMO)

Hull, N. C., Schooler, G. R., Binkovitz, L. A., Williamson, E. E., Araoz, P. A., Yu, L. & Young, P. M., Jan 3 2018, (Accepted/In press) In : Pediatric Radiology. 1 p.

Research output: Contribution to journalArticle

Dual-source multienergy CT with triple or quadruple x-ray beams

Yu, L., Ren, L., Li, Z., Leng, S. & McCollough, C. H., Jul 1 2018, In : Journal of Medical Imaging. 5, 3, 033502.

Research output: Contribution to journalArticle

8 Scopus citations

Evaluation of cross-sectional and longitudinal changes in volumetric bone mineral density in postmenopausal women using single- versus dual-energy quantitative computed tomography

Sfeir, J. G., Drake, M. M., Atkinson, E. J., Achenbach, S. J., Camp, J. J., Tweed, A. J., McCready, L. K., Yu, L., Adkins, M. C., Amin, S. & Khosla, S., Jul 1 2018, In : Bone. 112, p. 145-152 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Evaluation of projection- and dual-energy-based methods for metal artifact reduction in CT using a phantom study

Long, Z., Bruesewitz, M. R., Delone, D. R., Morris, J. M., Amrami, K. K., Adkins, M. C., Glazebrook, K. N., Kofler, J. M., Leng, S., McCollough, C. H., Fletcher, J. G., Halaweish, A. F. & Yu, L., Jan 1 2018, (Accepted/In press) In : Journal of Applied Clinical Medical Physics.

Research output: Contribution to journalArticle

3 Scopus citations

Inter-laboratory comparison of channelized hotelling observer computation

Ba, A., Abbey, C. K., Baek, J., Han, M., Bouwman, R. W., Balta, C., Brankov, J., Massanes, F., Gifford, H. C., Hernandez-Giron, I., Veldkamp, W. J. H., Petrov, D., Marshall, N., Samuelson, F. W., Zeng, R., Solomon, J. B., Samei, E., Timberg, P., Förnvik, H., Reiser, I. & 3 others, Yu, L., Gong, H. & Bochud, F. O., Jul 2018, In : Medical physics. 45, 7, p. 3019-3030 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Observer performance with varying radiation dose and reconstruction methods for detection of hepatic metastases

Fletcher, J. G., Fidler, J. L., Venkatesh, S. K., Hough, D. M., Takahashi, N. M., Yu, L., Johnson, M., Leng, S., Holmes III, D. R., Carter, R. E. & McCollough, C. H., Nov 1 2018, In : Radiology. 289, 2, p. 455-464 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

An effective noise reduction method for multi-energy CT images that exploit spatio-spectral features

Li, Z., Leng, S., Yu, L., Manduca, A. & McCollough, C. H., May 1 2017, In : Medical Physics. 44, 5, p. 1610-1623 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Chest computed tomography angiography in children on extracorporeal membrane oxygenation (ECMO)

Hull, N. C., Schooler, G. R., Binkovitz, L. A., Williamson, E. E., Araoz, P. A., Yu, L. & Young, P. M., Dec 7 2017, (Accepted/In press) In : Pediatric Radiology. p. 1-10 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Correlation between a 2D channelized Hotelling observer and human observers in a low-contrast detection task with multislice reading in CT

Yu, L., Chen, B., Kofler, J. M., Favazza, C. P., Leng, S., Kupinski, M. A. & McCollough, C. H., Aug 1 2017, In : Medical Physics. 44, 8, p. 3990-3999 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Estimating patient dose from CT exams that use automatic exposure control: Development and validation of methods to accurately estimate tube current values

Mcmillan, K., Bostani, M., Cagnon, C. H., Yu, L., Leng, S., McCollough, C. H. & Mcnitt-Gray, M. F., 2017, (Accepted/In press) In : Medical Physics.

Research output: Contribution to journalArticle

11 Scopus citations

Evaluation of a projection-domain lung nodule insertion technique in thoracic computed tomography

Ma, C., Yu, L., Chen, B., Koo, C. W., Takahashi, E. A., Fletcher, J. G., Levin, D. L., Kuzo, R. S., Viers, L. D., Vincent-Sheldon, S. A., Leng, S. & McCollough, C. H., Jan 1 2017, In : Journal of Medical Imaging. 4, 1, 013510.

Research output: Contribution to journalArticle

Low-dose CT for craniosynostosis: Preserving diagnostic benefit with substantial radiation dose reduction

Montoya, J. C., Eckel, L. J., DeLone, D. R., Kotsenas, A. L., Diehn, F. E., Yu, L., Bartley, A. C., Carter, R. E., McCollough, C. H. & Fletcher, J. G., Apr 1 2017, In : American Journal of Neuroradiology. 38, 4, p. 672-677 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Low-dose CT for the detection and classification of metastatic liver lesions: Results of the 2016 Low Dose CT Grand Challenge

McCollough, C. H., Bartley, A. C., Carter, R. E., Chen, B., Drees, T. A., Edwards, P., Holmes, D. R., Huang, A. E., Khan, F., Leng, S., McMillan, K. L., Michalak, G. J., Nunez, K. M., Yu, L. & Fletcher, J. G., Oct 2017, In : Medical physics. 44, 10, p. e339-e352

Research output: Contribution to journalArticle

21 Scopus citations

Low kV versus dual-energy virtual monoenergetic CT imaging for proven liver lesions: what are the advantages and trade-offs in conspicuity and image quality? A pilot study

Hanson, G. J., Michalak, G. J., Childs, R., McCollough, B., Kurup, A. N., Hough, D. M., Frye, J. M., Fidler, J. L., Venkatesh, S. K., Leng, S., Yu, L., Halaweish, A. F., Harmsen, W. S., McCollough, C. H. & Fletcher, J. G., Oct 5 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-9 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Selection of optimal tube potential settings for dual-energy CT virtual mono-energetic imaging of iodine in the abdomen

Michalak, G., Grimes, J., Fletcher, J. G., Halaweish, A., Yu, L., Leng, S. & McCollough, C. H., Apr 1 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-8 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Spectral performance of a whole-body research photon counting detector CT: Quantitative accuracy in derived image sets

Leng, S., Zhou, W., Yu, Z., Halaweish, A., Krauss, B., Schmidt, B., Yu, L., Kappler, S. & McCollough, C. H., Aug 21 2017, In : Physics in Medicine and Biology. 62, 17, p. 7216-7232 17 p.

Research output: Contribution to journalArticle

25 Scopus citations

Technical Note: Insertion of digital lesions in the projection domain for dual-source, dual-energy CT

Ferrero, A., Chen, B., Li, Z., Yu, L. & McCollough, C. H., May 1 2017, In : Medical Physics. 44, 5, p. 1655-1660 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
3 Scopus citations
2016

A robust noise reduction technique for time resolved CT

Li, Z., Yu, L., Leng, S., Williamson, E. E., Kotsenas, A. L., DeLone, D. R., Manduca, A. & McCollough, C. H., Jan 1 2016, In : Medical Physics. 43, 1, p. 347-359 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Construction of realistic phantoms from patient images and a commercial three-dimensional printer

Leng, S., Chen, B., Vrieze, T., Kuhlmann, J., Yu, L., Alexander, A., Matsumoto, J., Morris, J. & McCollough, C. H., Jul 1 2016, In : Journal of Medical Imaging. 3, 3, 033501.

Research output: Contribution to journalArticle

18 Scopus citations

Dealing with uncertainty in CT images

Fletcher, J. G., Leng, S., Yu, L. & McCollough, C. H., Apr 1 2016, In : Radiology. 279, 1, p. 5-10 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Estimation of Observer Performance for Reduced Radiation Dose Levels in CT. Eliminating Reduced Dose Levels That Are Too Low Is the First Step

Fletcher, J. G., Yu, L., Fidler, J. L., Levin, D. L., DeLone, D. R., Hough, D. M., Takahashi, N., Venkatesh, S. K., Sykes, A-M. G., White, D., Lindell, R. M., Kotsenas, A. L., Campeau, N. G., Lehman, V. T., Bartley, A. C., Leng, S., Holmes III, D. R., Toledano, A. Y., Carter, R. E. & McCollough, C. H., Aug 30 2016, (Accepted/In press) In : Academic Radiology.

Research output: Contribution to journalArticle

10 Scopus citations

Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array

Yu, Z., Leng, S., Jorgensen, S. M., Li, Z., Gutjahr, R., Chen, B., Halaweish, A. F., Kappler, S., Yu, L., Ritman, E. L. & McCollough, C. H., Feb 2 2016, In : Physics in Medicine and Biology. 61, 4, p. 1572-1595 24 p., 1572.

Research output: Contribution to journalArticle

100 Scopus citations

Human Imaging With Photon Counting–Based Computed Tomography at Clinical Dose Levels: Contrast-to-Noise Ratio and Cadaver Studies

Gutjahr, R., Halaweish, A. F., Yu, Z., Leng, S., Yu, L., Li, Z., Jorgensen, S. M., Ritman, E. L., Kappler, S. & McCollough, C. H., Jan 25 2016, (Accepted/In press) In : Investigative Radiology.

Research output: Contribution to journalArticle

85 Scopus citations

Impact of number of repeated scans on model observer performance for a low-contrast detection task in computed tomography

Ma, C., Yu, L., Chen, B., Favazza, C., Leng, S. & McCollough, C. H., Apr 1 2016, In : Journal of Medical Imaging. 3, 2, 023504.

Research output: Contribution to journalArticle

8 Scopus citations

Pediatric thoracic CT angiography at 70 kV: a phantom study to investigate the effects on image quality and radiation dose

MacDougall, R. D., Kleinman, P. L., Yu, L. & Lee, E. Y., Mar 17 2016, (Accepted/In press) In : Pediatric Radiology. p. 1-6 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Technical Note: Display window setting: An important factor for detecting subtle but clinically relevant artifacts in daily CT quality control

Long, Z., Bruesewitz, M. R., Sheedy, E. N., Powell, M. A., Kramer, J. C., Supalla, R. R., Colvin, C. M., Bechel, J. R., Favazza, C. P., Kofler, J. M., Leng, S., McCollough, C. H. & Yu, L., Dec 1 2016, In : Medical Physics. 43, 12, 4966698.

Research output: Contribution to journalArticle

1 Scopus citations

Technical Note: Improved CT number stability across patient size using dual-energy CT virtual monoenergetic imaging

Michalak, G., Grimes, J., Fletcher, J. G., Halaweish, A., Yu, L., Leng, S. & McCollough, C. H., Jan 1 2016, In : Medical Physics. 43, 1, p. 513-517 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Validation of a Projection-domain Insertion of Liver Lesions into CT Images

Chen, B., Ma, C., Leng, S., Fidler, J. L., Sheedy, S. P., McCollough, C. H., Fletcher, J. G. & Yu, L., Oct 1 2016, In : Academic Radiology. 23, 10, p. 1221-1229 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

A cross-platform survey of CT image quality and dose from routine abdomen protocols and a method to systematically standardize image quality

Favazza, C. P., Duan, X., Zhang, Y., Yu, L., Leng, S., Kofler, J. M., Bruesewitz, M. R. & McCollough, C. H., Oct 13 2015, In : Physics in Medicine and Biology. 60, 21, p. 8381-8397 17 p.

Research output: Contribution to journalArticle

3 Scopus citations
7 Scopus citations
12 Scopus citations
26 Scopus citations

Degradation of CT low-contrast spatial resolution due to the use of iterative reconstruction and reduced dose levels

McCollough, C. H., Yu, L., Kofler, J. M., Leng, S., Zhang, Y., Li, Z. & Carter, R. E., Aug 1 2015, In : Radiology. 276, 2, p. 499-506 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Dual- and multi-energy CT: Principles, technical approaches, and clinical applications

McCollough, C. H., Leng, S., Yu, L. & Fletcher, J. G., Sep 1 2015, In : Radiology. 276, 3, p. 637-653 17 p.

Research output: Contribution to journalArticle

420 Scopus citations