Lifeng Yu, PhD

  • 6009 Citations
  • 40 Scopus h-Index
20022020

Research output per year

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Research Output

2020

A Universal Protocol for Abdominal CT Examinations Performed on a Photon-Counting Detector CT System: A Feasibility Study

Zhou, W., Michalak, G. J., Weaver, J. M., Gong, H., Yu, L., McCollough, C. H. & Leng, S., Apr 1 2020, In : Investigative radiology. 55, 4, p. 226-232 7 p.

Research output: Contribution to journalArticle

Synthesizing images from multiple kernels using a deep convolutional neural network

Missert, A. D., Yu, L., Leng, S., Fletcher, J. G. & McCollough, C. H., Feb 1 2020, In : Medical physics. 47, 2, p. 422-430 9 p.

Research output: Contribution to journalArticle

2019

A deep learning- and partial least square regression-based model observer for a low-contrast lesion detection task in CT

Gong, H., Yu, L., Leng, S., Dilger, S. K., Ren, L., Zhou, W., Fletcher, J. G. & McCollough, C. H., May 2019, In : Medical physics. 46, 5, p. 2052-2063 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Clinical assessment of metal artifact reduction methods in dual-energy CT examinations of instrumented spines

Long, Z., De Lone, D. R., Kotsenas, A. L., Lehman, V. T., Nagelschneider, A. A., Michalak, G. J., Fletcher, J. G., McCollough, C. H. & Yu, L., Feb 1 2019, In : American Journal of Roentgenology. 212, 2, p. 395-401 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study

Dilger, S. K. N., Nelson, N., Venkatesh, S. K., Ehman, E., Fidler, J. L., Fletcher, J. G., McCollough, C. H. & Yu, L., Sep 1 2019, In : Investigative radiology. 54, 9, p. 572-579 8 p.

Research output: Contribution to journalArticle

Correlation between a deep-learning-based model observer and human observer for a realistic lung nodule localization task in chest CT

Gong, H., Walther, A., Hu, Q., Koo, C. W., Takahashi, E. A., Levin, D. L., Johnson, T. F., Hora, M. J., Leng, S., Fletcher, J. G., McCollough, C. H. & Yu, L., Jan 1 2019, Medical Imaging 2019: Image Perception, Observer Performance, and Technology Assessment. Nishikawa, R. M. & Samuelson, F. W. (eds.). SPIE, 109520K. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10952).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Evaluation of Lower-Dose Spiral Head CT for Detection of Intracranial Findings Causing Neurologic Deficits

Fletcher, J. G., DeLone, D. R., Kotsenas, A. L., Campeau, N. G., Lehman, V. T., Yu, L., Leng, S., Holmes, D. R., Edwards, P. K., Johnson, M. P., Michalak, G. J., Carter, R. E. & McCollough, C. H., Nov 1 2019, In : AJNR. American journal of neuroradiology. 40, 11, p. 1855-1863 9 p.

Research output: Contribution to journalArticle

Open Access

Impact of prior information on material decomposition in dual- and multienergy computed tomography

Ren, L., Tao, S., Rajendran, K., McCollough, C. H. & Yu, L., Jan 1 2019, In : Journal of Medical Imaging. 6, 1, 013503.

Research output: Contribution to journalArticle

2 Scopus citations

Lead shielding in pediatric chest CT: Effect of apron placement outside the scan volume on radiation dose reduction

Yu, L., Bruesewitz, M. R., Vrieze, T. J. & McCollough, C. H., Jan 1 2019, In : American Journal of Roentgenology. 212, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2 Scopus citations

Low-Dose CT Image Denoising Using Cycle-Consistent Adversarial Networks

Li, Z., Huang, J., Yu, L., Chi, Y. & Jin, M., Oct 2019, 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2019. Institute of Electrical and Electronics Engineers Inc., 9059965. (2019 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2019).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Material decomposition in photon-counting-detector CT: Threshold or bin images?

Ren, L., Tao, S., McCollough, C. H. & Yu, L., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109482S. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Multi-energy CT with triple x-ray beams and photon-counting-detector CT for simultaneous imaging of two contrast agents: An experimental comparison

Ren, L., McCollough, C. H. & Yu, L., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109481B. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Quantitative accuracy and dose efficiency of dual-contrast imaging using dual-energy CT: a phantom study

Ren, L., Rajendran, K., McCollough, C. H. & Yu, L., Jan 1 2019, (Accepted/In press) In : Medical physics.

Research output: Contribution to journalArticle

1 Scopus citations

Radiation dose efficiency of multi-energy photon-counting-detector CT for dual-contrast imaging

Ren, L., Rajendran, K., McCollough, C. H. & Yu, L., Dec 13 2019, In : Physics in medicine and biology. 64, 24, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Simulation of CT images reconstructed with different kernels using a convolutional neural network and its implications for efficient CT workflow

Missert, A. D., Leng, S., McCollough, C. H., Fletcher, J. G. & Yu, L., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109482Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

State of the art in abdominal CT: The limits of iterative reconstruction algorithms

Mileto, A., Guimaraes, L. S., McCollough, C. H., Fletcher, J. G. & Yu, L., Jan 1 2019, In : Radiology. 293, 3, p. 491-503 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Technical Note: Increased photon starvation artifacts at low helical pitch in ultra-low-dose CT

Browne, J. E., Bruesewitz, M. R., Vrieze, T. J., McCollough, C. H. & Yu, L., Dec 1 2019, In : Medical physics. 46, 12, p. 5538-5543 6 p.

Research output: Contribution to journalArticle

2018

Breathe New Life Into Your Chest CT Exams: Using Advanced Acquisition and Postprocessing Techniques

Weber, N. M., Koo, C. W., Yu, L., Bartholmai, B. J., Halaweish, A. F., McCollough, C. H. & Fletcher, J. G., Jan 1 2018, (Accepted/In press) In : Current Problems in Diagnostic Radiology.

Research output: Contribution to journalArticle

2 Scopus citations

Correction to: Chest computed tomography angiography in children on extracorporeal membrane oxygenation (ECMO)

Hull, N. C., Schooler, G. R., Binkovitz, L. A., Williamson, E. E., Araoz, P. A., Yu, L. & Young, P. M., Jan 3 2018, (Accepted/In press) In : Pediatric Radiology. 1 p.

Research output: Contribution to journalArticle

Correlation between model observers in uniform background and human observers in patient liver background for a low-contrast detection task in CT

Gong, H., Yu, L., Leng, S., DIlger, S., Zhou, W., Ren, L. & McCollough, C. H., Jan 1 2018, Medical Imaging 2018: Image Perception, Observer Performance, and Technology Assessment. Samuelson, F. W. & Nishikawa, R. M. (eds.). SPIE, 105770M. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10577).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Dual-source multienergy CT with triple or quadruple x-ray beams

Yu, L., Ren, L., Li, Z., Leng, S. & McCollough, C. H., Jul 1 2018, In : Journal of Medical Imaging. 5, 3, 033502.

Research output: Contribution to journalArticle

10 Scopus citations

Evaluation of cross-sectional and longitudinal changes in volumetric bone mineral density in postmenopausal women using single- versus dual-energy quantitative computed tomography

Sfeir, J. G., Drake, M. M., Atkinson, E. J., Achenbach, S. J., Camp, J. J., Tweed, A. J., McCready, L. K., Yu, L., Adkins, M. C., Amin, S. & Khosla, S., Jul 1 2018, In : Bone. 112, p. 145-152 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Evaluation of projection- and dual-energy-based methods for metal artifact reduction in CT using a phantom study

Long, Z., Bruesewitz, M. R., Delone, D. R., Morris, J. M., Amrami, K. K., Adkins, M. C., Glazebrook, K. N., Kofler, J. M., Leng, S., McCollough, C. H., Fletcher, J. G., Halaweish, A. F. & Yu, L., Jan 1 2018, (Accepted/In press) In : Journal of Applied Clinical Medical Physics.

Research output: Contribution to journalArticle

4 Scopus citations

Inter-laboratory comparison of channelized hotelling observer computation

Ba, A., Abbey, C. K., Baek, J., Han, M., Bouwman, R. W., Balta, C., Brankov, J., Massanes, F., Gifford, H. C., Hernandez-Giron, I., Veldkamp, W. J. H., Petrov, D., Marshall, N., Samuelson, F. W., Zeng, R., Solomon, J. B., Samei, E., Timberg, P., Förnvik, H., Reiser, I. & 3 others, Yu, L., Gong, H. & Bochud, F. O., Jul 2018, In : Medical physics. 45, 7, p. 3019-3030 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Motion-compensated reconstruction for limited-angle multiphase cardiac CT

Jin, M., Zhao, C., Jia, X. & Yu, L., Jan 1 2018, Medical Imaging 2018: Physics of Medical Imaging. Schmidt, T. G., Chen, G-H. & Lo, J. Y. (eds.). SPIE, Vol. 10573. 1057333

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Observer performance with varying radiation dose and reconstruction methods for detection of hepatic metastases

Fletcher, J. G., Fidler, J. L., Venkatesh, S. K., Hough, D. M., Takahashi, N. M., Yu, L., Johnson, M., Leng, S., Holmes III, D. R., Carter, R. E. & McCollough, C. H., Nov 1 2018, In : Radiology. 289, 2, p. 455-464 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Simulating low-dose cone-beam CT: A phantom study

Ferrero, A., Fetterly, K., Yu, L. & Schueler, B. A., Jan 1 2018, Medical Imaging 2018: Physics of Medical Imaging. SPIE, Vol. 10573. 1057347

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Three-material decomposition in multi-energy CT: Impact of prior information on noise and bias

Ren, L., McCollough, C. H. & Yu, L., Jan 1 2018, Medical Imaging 2018: Physics of Medical Imaging. SPIE, Vol. 10573. 105731G

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations
2017

An effective noise reduction method for multi-energy CT images that exploit spatio-spectral features

Li, Z., Leng, S., Yu, L., Manduca, A. & McCollough, C. H., May 1 2017, In : Medical Physics. 44, 5, p. 1610-1623 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

A virtual clinical trial using projection-based nodule insertion to determine radiologist reader performance in lung cancer screening CT

Yu, L., Hu, Q., Koo, C. W., Takahashi, E. A., Levin, D. L., Johnson, T., Hora, M. J., Dirks, S., Chen, B., McMillan, K., Leng, S., Fletcher, J. G. & McCollough, C. H., 2017, Medical Imaging 2017: Physics of Medical Imaging. SPIE, Vol. 10132. 101321R

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Chest computed tomography angiography in children on extracorporeal membrane oxygenation (ECMO)

Hull, N. C., Schooler, G. R., Binkovitz, L. A., Williamson, E. E., Araoz, P. A., Yu, L. & Young, P. M., Dec 7 2017, (Accepted/In press) In : Pediatric Radiology. p. 1-10 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Correlation between a 2D channelized Hotelling observer and human observers in a low-contrast detection task with multislice reading in CT

Yu, L., Chen, B., Kofler, J. M., Favazza, C. P., Leng, S., Kupinski, M. A. & McCollough, C. H., Aug 1 2017, In : Medical Physics. 44, 8, p. 3990-3999 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Estimating patient dose from CT exams that use automatic exposure control: Development and validation of methods to accurately estimate tube current values

Mcmillan, K., Bostani, M., Cagnon, C. H., Yu, L., Leng, S., McCollough, C. H. & Mcnitt-Gray, M. F., 2017, (Accepted/In press) In : Medical Physics.

Research output: Contribution to journalArticle

11 Scopus citations

Evaluation of a projection-domain lung nodule insertion technique in thoracic computed tomography

Ma, C., Yu, L., Chen, B., Koo, C. W., Takahashi, E. A., Fletcher, J. G., Levin, D. L., Kuzo, R. S., Viers, L. D., Vincent-Sheldon, S. A., Leng, S. & McCollough, C. H., Jan 1 2017, In : Journal of Medical Imaging. 4, 1, 013510.

Research output: Contribution to journalArticle

Learning-based stochastic object models for use in optimizing imaging systems

Dolly, S. R., Anastasio, M. A., Yu, L. & Li, H., 2017, Medical Imaging 2017: Physics of Medical Imaging. SPIE, Vol. 10132. 101321T

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Low-dose CT for craniosynostosis: Preserving diagnostic benefit with substantial radiation dose reduction

Montoya, J. C., Eckel, L. J., DeLone, D. R., Kotsenas, A. L., Diehn, F. E., Yu, L., Bartley, A. C., Carter, R. E., McCollough, C. H. & Fletcher, J. G., Apr 1 2017, In : American Journal of Neuroradiology. 38, 4, p. 672-677 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Low-dose CT for the detection and classification of metastatic liver lesions: Results of the 2016 Low Dose CT Grand Challenge

McCollough, C. H., Bartley, A. C., Carter, R. E., Chen, B., Drees, T. A., Edwards, P., Holmes, D. R., Huang, A. E., Khan, F., Leng, S., McMillan, K. L., Michalak, G. J., Nunez, K. M., Yu, L. & Fletcher, J. G., Oct 2017, In : Medical physics. 44, 10, p. e339-e352

Research output: Contribution to journalArticle

24 Scopus citations

Low kV versus dual-energy virtual monoenergetic CT imaging for proven liver lesions: what are the advantages and trade-offs in conspicuity and image quality? A pilot study

Hanson, G. J., Michalak, G. J., Childs, R., McCollough, B., Kurup, A. N., Hough, D. M., Frye, J. M., Fidler, J. L., Venkatesh, S. K., Leng, S., Yu, L., Halaweish, A. F., Harmsen, W. S., McCollough, C. H. & Fletcher, J. G., Oct 5 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-9 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Practical implementation of channelized hotelling observers: Effect of ROI size

Ferrero, A., Favazza, C. P., Yu, L., Leng, S. & McCollough, C. H., 2017, Medical Imaging 2017: Physics of Medical Imaging. SPIE, Vol. 10132. 101320G

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Selection of optimal tube potential settings for dual-energy CT virtual mono-energetic imaging of iodine in the abdomen

Michalak, G., Grimes, J., Fletcher, J. G., Halaweish, A., Yu, L., Leng, S. & McCollough, C. H., Apr 1 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-8 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Spectral performance of a whole-body research photon counting detector CT: Quantitative accuracy in derived image sets

Leng, S., Zhou, W., Yu, Z., Halaweish, A., Krauss, B., Schmidt, B., Yu, L., Kappler, S. & McCollough, C. H., Aug 21 2017, In : Physics in Medicine and Biology. 62, 17, p. 7216-7232 17 p.

Research output: Contribution to journalArticle

26 Scopus citations

Task-based image quality assessment in radiation therapy: Initial characterization and demonstration with CT simulation images

Dolly, S. R., Anastasio, M. A., Yu, L. & Li, H., 2017, Medical Imaging 2017: Image Perception, Observer Performance, and Technology Assessment. SPIE, Vol. 10136. 101360Y

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Technical Note: Insertion of digital lesions in the projection domain for dual-source, dual-energy CT

Ferrero, A., Chen, B., Li, Z., Yu, L. & McCollough, C. H., May 1 2017, In : Medical Physics. 44, 5, p. 1655-1660 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
3 Scopus citations
2016

An open library of CT patient projection data

Chen, B., Leng, S., Yu, L., Holmes III, D. R., Fletcher, J. G. & McCollough, C. H., 2016, Medical Imaging 2016: Physics of Medical Imaging. SPIE, Vol. 9783. 97831B

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Scopus citations

A robust noise reduction technique for time resolved CT

Li, Z., Yu, L., Leng, S., Williamson, E. E., Kotsenas, A. L., DeLone, D. R., Manduca, A. & McCollough, C. H., Jan 1 2016, In : Medical Physics. 43, 1, p. 347-359 13 p.

Research output: Contribution to journalArticle

7 Scopus citations