Lewis Rowland Roberts, MB, ChB, PhD

  • 16866 Citations
  • 70 Scopus h-Index
1991 …2020
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Research Output 1991 2019

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Article
2015
35 Citations (Scopus)

Vasodilator-stimulated phosphoprotein promotes activation of hepatic stellate cells by regulating Rab11-dependent plasma membrane targeting of transforming growth factor beta receptors

Tu, K., Li, J., Verma, V. K., Liu, C., Billadeau, D. D., Lamprecht, G., Xiang, X., Guo, L., Dhanasekaran, R., Roberts, L. R., Shah, V. & Kang, N., Jan 1 2015, In : Hepatology. 61, 1, p. 361-374 14 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta Receptors
Hepatic Stellate Cells
Cell Membrane
Transforming Growth Factor beta
Liver
2014
41 Citations (Scopus)

A new clinically based staging system for perihilar cholangiocarcinoma

Chaiteerakij, R., Harmsen, W. S., Marrero, C. R., Aboelsoud, M. M., Ndzengue, A., Kaiya, J., Therneau, T. M., Sanchez, W., Gores, G. J. & Roberts, L. R., Dec 11 2014, In : American Journal of Gastroenterology. 109, 12, p. 1881-1890 10 p.

Research output: Contribution to journalArticle

Klatskin Tumor
Survival
Clinical Trials
Neoplasms
Neoplasm Metastasis
32 Citations (Scopus)

Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling

Nakamura, I., Zakharia, K., Banini, B. A., Mikhail, D. S., Kim, T. H., Yang, J. D., Moser, C. D., Shaleh, H. M., Thornburgh, S. R., Walters, I. & Roberts, L. R., Apr 7 2014, In : PLoS One. 9, 4, e92273.

Research output: Contribution to journalArticle

platelet-derived growth factor
liver cirrhosis
Platelet-Derived Growth Factor
Liver
Vascular Endothelial Growth Factor A
8 Citations (Scopus)

Cervical cancer screening in Ghana, West Africa: Prevalence of abnormal cytology and challenges for expanding screening

Handlogten, K. S., Molitor, R. J., Roeker, L. E., Narla, N. P., Bachman, M. J., Quayson, S., Owusu-Afriyie, O., Adjei, E., Ankobea, F., Clayton, A., Roberts, L. R., Mac Laughlin, K. & Ansong, D., Mar 2014, In : International Journal of Gynecological Pathology. 33, 2, p. 197-202 6 p.

Research output: Contribution to journalArticle

Ghana
Western Africa
Early Detection of Cancer
Uterine Cervical Neoplasms
Cell Biology
162 Citations (Scopus)

Chemopreventive strategies in hepatocellular carcinoma

Singh, S., Singh, P. P., Roberts, L. R. & Sanchez, W., Jan 2014, In : Nature Reviews Gastroenterology and Hepatology. 11, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Antiviral Agents
Oil and Gas Fields
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Fish Oils
76 Citations (Scopus)

Continuation of metformin use after a diagnosis of cirrhosis significantly improves survival of patients with diabetes

Zhang, X., Harmsen, W. S., Mettler, T. A., Kim, W. R., Roberts, R. O., Therneau, T. M., Roberts, L. R. & Chaiteerakij, R., Dec 1 2014, In : Hepatology. 60, 6, p. 2008-2016 9 p.

Research output: Contribution to journalArticle

Metformin
Fibrosis
Survival
Confidence Intervals
Lactic Acidosis
37 Citations (Scopus)

Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis

Hlady, R. A., Tiedemann, R. L., Puszyk, W., Zendejas, I., Roberts, L. R., Choi, J. H., Liu, C. & Robertson, K. D., 2014, In : Oncotarget. 5, 19, p. 9425-9443 19 p.

Research output: Contribution to journalArticle

Epigenomics
Hepatitis
Alcoholism
Hepatocellular Carcinoma
Infection
88 Citations (Scopus)

Fibroblast growth factor receptor 2 translocations in intrahepatic cholangiocarcinoma

Graham, R., Barr Fritcher, E. G., Pestova, E., Schulz, J., Sitailo, L. A., Vasmatzis, G., Murphy, S. J., Mc Williams, R. R., Hart, S., Halling, K. C., Roberts, L. R., Gores, G. J., Couch, F. J., Zhang, L., Borad, M. J. & Kipp, B. R., 2014, In : Human Pathology. 45, 8, p. 1630-1638 9 p.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 2
Cholangiocarcinoma
Bile Duct Neoplasms
Neoplasms
Fluorescence In Situ Hybridization
47 Citations (Scopus)

Fibroblast growth factor signaling in liver carcinogenesis

Sandhu, D. S., Baichoo, E. & Roberts, L. R., Mar 2014, In : Hepatology. 59, 3, p. 1166-1173 8 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factors
Hepatocellular Carcinoma
Carcinogenesis
Tumor Microenvironment
Liver
12 Citations (Scopus)

Heat stress induced cell death mechanisms in hepatocytes and hepatocellular carcinoma: In vitro and in vivo study

Thompson, S. M., Callstrom, M. R., Butters, K. A., Knudsen, B., Grande, J. P., Roberts, L. R. & Woodrum, D. A., 2014, In : Lasers in Surgery and Medicine. 46, 4, p. 290-301 12 p.

Research output: Contribution to journalArticle

Hepatocytes
Hepatocellular Carcinoma
Cell Death
Hot Temperature
Caspase 3
27 Citations (Scopus)

Liver masses: A clinical, radiologic, and pathologic perspective

Venkatesh, S. K., Chandan, V. & Roberts, L. R., 2014, In : Clinical Gastroenterology and Hepatology. 12, 9, p. 1414-1429 16 p.

Research output: Contribution to journalArticle

Liver
Neoplasm Staging
Delayed Diagnosis
Physical Examination
Blood Vessels
13 Citations (Scopus)

Metformin does not improve survival in patients with hepatocellular carcinoma

Bhat, M., Chaiteerakij, R., Harmsen, W. S., Schleck, C. D., Yang, J. D., Giama, N. H., Therneau, T. M., Gores, G. J. & Roberts, L. R., Nov 14 2014, In : World Journal of Gastroenterology. 20, 42, p. 15750-15755 6 p.

Research output: Contribution to journalArticle

Metformin
Hepatocellular Carcinoma
Survival
Liver Diseases
Alcoholic Liver Diseases
25 Citations (Scopus)

Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis

Rizvi, S., Mertens, J. C., Bronk, S. F., Hirsova, P., Dai, H., Roberts, L. R., Kaufmann, S. H. & Gores, G. J., Aug 15 2014, In : Journal of Biological Chemistry. 289, 33, p. 22835-22849 15 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor
Fibroblasts
Puma
Apoptosis
Myofibroblasts
5 Citations (Scopus)
Signal Transducing Adaptor Proteins
Bile Duct Neoplasms
CD4-Positive T-Lymphocytes
Tumor-Infiltrating Lymphocytes
Intrahepatic Bile Ducts
13 Citations (Scopus)
Hepatocellular Carcinoma
Stem Cells
Hot Temperature
Animal Care Committees
Heat-Shock Response
19 Citations (Scopus)

Short and long telomeres increase risk of amnestic mild cognitive impairment

Roberts, R. O., Boardman, L. A., Cha, R. H., Pankratz, V. S., Johnson, R. A., Druliner, B. R., Christianson, T. J. H., Roberts, L. R. & Petersen, R. C., Nov 1 2014, In : Mechanisms of Ageing and Development. 141-142, p. 64-69 6 p.

Research output: Contribution to journalArticle

Telomere
Alzheimer Disease
Confidence Intervals
Cognitive Dysfunction
Polymerase Chain Reaction
61 Citations (Scopus)

Treating hepatitis C in lower-income countries

Jayasekera, C. R., Barry, M., Roberts, L. R. & Nguyen, M. H., 2014, In : New England Journal of Medicine. 370, 20, p. 1869-1871 3 p.

Research output: Contribution to journalArticle

2013
19 Citations (Scopus)

Activation of the transcription factor gli1 by wnt signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration

Nakamura, I., Fernandez-Barrena, M. G., Ortiz-Ruiz, M. C., Almada, L. L., Hu, C., Elsawa, S. F., Mills, L. D., Romecin, P. A., Gulaid, K. H., Moser, C. D., Han, J. J., Vrabel, A., Hanse, E. A., Akogyeram, N. A., Albrecht, J. H., Monga, S. P. S., Sanderson, S. O., Prieto, J., Roberts, L. R. & Fernandez-Zapico, M. E., Jul 19 2013, In : Journal of Biological Chemistry. 288, 29, p. 21389-21398 10 p.

Research output: Contribution to journalArticle

Tissue regeneration
Regeneration
Transcription Factors
Chemical activation
Sulfatases
13 Citations (Scopus)

AS30D model of hepatocellular carcinoma: Tumorigenicity and preliminary characterization by imaging, histopathology, and immunohistochemistry

Thompson, S. M., Callstrom, M. R., Knudsen, B., Anderson, J. L., Butters, K. A., Grande, J. P., Roberts, L. R. & Woodrum, D. A., Feb 2013, In : CardioVascular and Interventional Radiology. 36, 1, p. 198-203 6 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Immunohistochemistry
Liver
Cell Line
Neoplasms
74 Citations (Scopus)

Efficacy and safety of transarterial radioembolization versus chemoembolization in patients with hepatocellular carcinoma

Moreno-Luna, L. E., Yang, J. D., Sanchez, W., Paz-Fumagalli, R., Harnois, D., Mettler, T. A., Gansen, D. N., De Groen, P. C., Lazaridis, K. N., Narayanan Menon, K. V., La Russo, N. F., Alberts, S. R., Gores, G. J., Fleming, C. J., Slettedahl, S. W., Harmsen, W. S., Therneau, T. M., Wiseman, G. A., Andrews, J. C. & Roberts, L. R., Jun 2013, In : CardioVascular and Interventional Radiology. 36, 3, p. 714-723 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Safety
Fatigue
Fever
Therapeutics
313 Citations (Scopus)

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

Jiao, Y., Pawlik, T. M., Anders, R. A., Selaru, F. M., Streppel, M. M., Lucas, D. J., Niknafs, N., Guthrie, V. B., Maitra, A., Argani, P., Offerhaus, G. J. A., Roa, J. C., Roberts, L. R., Gores, G. J., Popescu, I., Alexandrescu, S. T., Dima, S., Fassan, M., Simbolo, M., Mafficini, A. & 16 others, Capelli, P., Lawlor, R. T., Ruzzenente, A., Guglielmi, A., Tortora, G., De Braud, F., Scarpa, A., Jarnagin, W., Klimstra, D., Karchin, R., Velculescu, V. E., Hruban, R. H., Vogelstein, B., Kinzler, K. W., Papadopoulos, N. & Wood, L. D., Dec 2013, In : Nature Genetics. 45, 12, p. 1470-1473 4 p.

Research output: Contribution to journalArticle

Exome
Cholangiocarcinoma
Mutation
Chromatin Assembly and Disassembly
Genes
5 Citations (Scopus)

Genetic alterations in advanced HBV-related HCC with portal vein tumor thrombosis: Insights from next generation DNA sequencing

Chaiteerakij, R. & Roberts, L. R., May 2013, In : Journal of Hepatology. 58, 5, p. 1042-1044 3 p.

Research output: Contribution to journalArticle

Portal Vein
DNA Sequence Analysis
Hepatitis B virus
Hepatocellular Carcinoma
Thrombosis
49 Citations (Scopus)

Identification of Rtl1, a Retrotransposon-Derived Imprinted Gene, as a Novel Driver of Hepatocarcinogenesis

Riordan, J. D., Keng, V. W., Tschida, B. R., Scheetz, T. E., Bell, J. B., Podetz-Pedersen, K. M., Moser, C. D., Copeland, N. G., Jenkins, N. A., Roberts, L. R., Largaespada, D. A. & Dupuy, A. J., Apr 2013, In : PLoS Genetics. 9, 4, e1003441.

Research output: Contribution to journalArticle

Retroelements
retrotransposons
tumor
gene
domestication
14 Citations (Scopus)

Molecular bioluminescence imaging as a noninvasive tool for monitoring tumor growth and therapeutic response to MRI-guided laser ablation in a rat model of hepatocellular carcinoma

Thompson, S. M., Callstrom, M. R., Knudsen, B. E., Anderson, J. L., Sutor, S. L., Butters, K. A., Kuo, C., Grande, J. P., Roberts, L. R. & Woodrum, D. A., Jun 2013, In : Investigative Radiology. 48, 6, p. 413-421 9 p.

Research output: Contribution to journalArticle

Molecular Imaging
Laser Therapy
Hepatocellular Carcinoma
Magnetic Resonance Imaging
Luminescence
89 Citations (Scopus)

Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions

Voss, J. S., Holtegaard, L. M., Kerr, S. E., Fritcher, E. G. B., Roberts, L. R., Gores, G. J., Zhang, J., Highsmith, W. E. J., Halling, K. C. & Kipp, B. R., Jul 2013, In : Human Pathology. 44, 7, p. 1216-1222 7 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Mutation
Oncogenes
Therapeutics
Paraffin
185 Citations (Scopus)

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

Wang, P., Dong, Q., Zhang, C., Kuan, P. F., Liu, Y., Jeck, W. R., Andersen, J. B., Jiang, W., Savich, G. L., Tan, T. X., Auman, J. T., Hoskins, J. M., Misher, A. D., Moser, C. D., Yourstone, S. M., Kim, J. W., Cibulskis, K., Getz, G., Hunt, H. V., Thorgeirsson, S. S. & 6 others, Roberts, L. R., Ye, D., Guan, K. L., Xiong, Y., Qin, L. X. & Chiang, D. Y., Jun 20 2013, In : Oncogene. 32, 25, p. 3091-3100 10 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Cholangiocarcinoma
Glioblastoma
Mutation
5-Methylcytosine
46 Citations (Scopus)

Primary sclerosing cholangitis with equivocal cytology: Fluorescence in situ hybridization and serum ca 19-9 predict risk of malignancy

Fritcher, E. G. B., Voss, J. S., Jenkins, S. M., Lingineni, R. K., Clayton, A. C., Roberts, L. R., Halling, K. C., Talwalkar, J. A., Gores, G. J. & Kipp, B. R., Sep 2013, In : Cancer cytopathology. 121, 12, p. 708-717 10 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Fluorescence In Situ Hybridization
Cell Biology
Serum
Neoplasms

Reply

Chaiteerakij, R., Harmsen, W. S., Ryu, E., Roberts, R. O., Olson, J. E., Therneau, T. M. & Roberts, L. R., Nov 2013, In : Hepatology. 58, 5, p. 1863 1 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Metformin
Liver Neoplasms
Diabetes Mellitus
76 Citations (Scopus)

Risk factors for intrahepatic cholangiocarcinoma: Association between metformin use and reduced cancer risk

Chaiteerakij, R., Yang, J. D., Harmsen, W. S., Slettedahl, S. W., Mettler, T. A., Fredericksen, Z. S., Kim, W. R., Gores, G. J., Roberts, R. O., Olson, J. E., Therneau, T. M. & Roberts, L. R., Feb 2013, In : Hepatology. 57, 2, p. 648-655 8 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Metformin
Odds Ratio
Neoplasms
Confidence Intervals
27 Citations (Scopus)

The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling

Zheng, X., Gai, X., Han, S., Moser, C. D., Hu, C., Shire, A. M., Floyd, R. A. & Roberts, L. R., Mar 2013, In : Genes Chromosomes and Cancer. 52, 3, p. 225-236 12 p.

Research output: Contribution to journalArticle

Sulfatases
Hepatocellular Carcinoma
OKN 007
Catenins
Neoplasms
81 Citations (Scopus)

Therapeutic effects of deleting cancer-associated fibroblasts in cholangiocarcinoma

Mertens, J. C., Fingas, C. D., Christensen, J. D., Smoot, R., Bronk, S. F., Werneburg, N. W., Gustafson, M., Dietz, A. B., Roberts, L. R., Sirica, A. E. & Gores, G. J., Jan 15 2013, In : Cancer Research. 73, 2, p. 897-907 11 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Therapeutic Uses
Neoplasms
Apoptosis
Cell Death
2012
41 Citations (Scopus)

Biliary tract cancers in olmsted county, Minnesota, 1976-2008

Yang, J. D., Kim, B., Sanderson, S. O., St. Sauver, J., Yawn, B. P., Larson, J. J., Therneau, T. M., Roberts, L. R., Gores, G. J. & Kim, W. R., Aug 2012, In : American Journal of Gastroenterology. 107, 8, p. 1256-1262 7 p.

Research output: Contribution to journalArticle

Biliary Tract Neoplasms
Survival
Incidence
Gallbladder Neoplasms
Cholangiocarcinoma
25 Citations (Scopus)

Comparison of methods to detect neoplasia in patients undergoing endoscopic ultrasound-guided fine-needle aspiration

Levy, M. J., Oberg, T. N., Campion, M. B., Clayton, A. C., Halling, K. C., Henry, M. R., Kipp, B. R., Sebo, T. J., Zhang, J., Enders, F. T., Clain, J. E., Gleeson, F. C., Rajan, E., Roberts, L. R., Topazian, M., Wang, K. K. N. & Gores, G. J., May 2012, In : Gastroenterology. 142, 5

Research output: Contribution to journalArticle

Endoscopic Ultrasound-Guided Fine Needle Aspiration
Cell Biology
Fluorescence In Situ Hybridization
Fine Needle Biopsy
Endosonography
18 Citations (Scopus)
Interventional Magnetic Resonance Imaging
Hepatocellular Carcinoma
Tumor Burden
Ligation
Liver
36 Citations (Scopus)

Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo

Shao, H., Gao, C., Tang, H., Zhang, H., Roberts, L. R., Hylander, B. L., Repasky, E. A., Ma, W. W., Qiu, J., Adjei, A., Dy, G. K. & Yu, C., Jan 2012, In : Journal of Hepatology. 56, 1, p. 176-183 8 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Liver Neoplasms
Hepatocellular Carcinoma
Neoplasms
Phosphotransferases
246 Citations (Scopus)

Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors

Andersen, J. B., Spee, B., Blechacz, B. R., Avital, I., Komuta, M., Barbour, A., Conner, E. A., Gillen, M. C., Roskams, T., Roberts, L. R., Factor, V. M. & Thorgeirsson, S. S., Apr 2012, In : Gastroenterology. 142, 4

Research output: Contribution to journalArticle

Cholangiocarcinoma
Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor
Mutation
Therapeutics
18 Citations (Scopus)

Hepatic artery embolization for neuroendocrine tumors: Postprocedural management and complications

Lewis, M. A., Jaramillo, S., Roberts, L. R., Fleming, C. J., Rubin, J. & Grothey, A. F., 2012, In : Oncologist. 17, 5, p. 725-731 7 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Hepatic Artery
Liver Function Tests
Length of Stay
Carcinoid Tumor
30 Citations (Scopus)

Hepatocellular carcinoma in Olmsted County, Minnesota, 1976-2008

Yang, J. D., Kim, B., Sanderson, S. O., St. Sauver, J., Yawn, B. P., Pedersen, R. A., Larson, J. J., Therneau, T. M., Roberts, L. R. & Kim, W. R., 2012, In : Mayo Clinic Proceedings. 87, 1, p. 9-16 8 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Survival
Incidence
Hepacivirus
Medical Record Linkage
115 Citations (Scopus)

Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma

Kipp, B. R., Voss, J. S., Kerr, S. E., Barr Fritcher, E. G., Graham, R., Zhang, L., Highsmith, W. E. J., Zhang, J., Roberts, L. R., Gores, G. J. & Halling, K. C., Oct 2012, In : Human Pathology. 43, 10, p. 1552-1558 7 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Cholangiocarcinoma
Mutation
Codon
Brain Neoplasms
43 Citations (Scopus)

Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas

Mao, J., Yu, H., Wang, C., Sun, L., Jiang, W., Zhang, P., Xiao, Q., Han, D., Saiyin, H., Zhu, J., Chen, T., Roberts, L. R., Huang, H. & Yu, L., Dec 2012, In : Carcinogenesis. 33, 12, p. 2568-2577 10 p., bgs287.

Research output: Contribution to journalArticle

Metallothionein
Hepatocellular Carcinoma
Neoplasms
Carcinogenesis
Tumor Necrosis Factor-alpha
131 Citations (Scopus)

miR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma

Razumilava, N., Bronk, S. F., Smoot, R. L., Fingas, C. D., Werneburg, N. W., Roberts, L. R. & Mott, J. L., Feb 2012, In : Hepatology. 55, 2, p. 465-475 11 p.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand Receptors
Cholangiocarcinoma
MicroRNAs
TNF-Related Apoptosis-Inducing Ligand
Apoptosis
44 Citations (Scopus)

Model to estimate survival in ambulatory patients with hepatocellular carcinoma

Yang, J. D., Kim, W. R., Park, K. W., Chaiteerakij, R., Kim, B., Sanderson, S. O., Larson, J. J., Pedersen, R. A., Therneau, T. M., Gores, G. J., Roberts, L. R. & Park, J. W., Aug 2012, In : Hepatology. 56, 2, p. 614-621 8 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Hepatocellular Carcinoma
Survival
Liver Diseases
Neoplasms
75 Citations (Scopus)

Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment

Yaqoob, U., Cao, S., Shergill, U., Jagavelu, K., Geng, Z., Yin, M., De Assuncao, T. M., Cao, Y., Szabolcs, A., Thorgeirsson, S., Schwartz, M., Yang, J. D., Ehman, R. L., Roberts, L. R., Mukhopadhyay, D. & Shah, V., Aug 15 2012, In : Cancer Research. 72, 16, p. 4047-4059 13 p.

Research output: Contribution to journalArticle

Neuropilin-1
Tumor Microenvironment
Fibronectins
Myofibroblasts
Growth
7 Citations (Scopus)

Phase II, open-label study of brivanib as first-line therapy in patients with advanced hepatocellular carcinoma

Garcia, J. A. & Roberts, L. R., Feb 2012, In : Journal of Hepatology. 56, 2, p. 486-487 2 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Therapeutics
brivanib
14 Citations (Scopus)

Potentially curative treatment in patients with hepatocellular cancer-results from the liver cancer research network

Kanwal, F., Befeler, A., Chari, R. S., Marrero, J., Kahn, J., Afdhal, N., Morgan, T., Roberts, L. R., Mohanty, S. R., Schwartz, J., Vanthiel, D., Li, J., Zeringue, A. & Di'Bisceglie, A., Aug 2012, In : Alimentary Pharmacology and Therapeutics. 36, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Research
Therapeutics
Survival
Liver Transplantation
10 Citations (Scopus)

Prevention of hepatocellular carcinoma: Progress and challenges

Shire, A. M. & Roberts, L. R., Mar 2012, In : Minerva Gastroenterologica e Dietologica. 58, 1, p. 49-64 16 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Liver Diseases
Aflatoxins
Virus Diseases
Fatty Liver

Reply

Yang, J. D., Enders, F. T., Therneau, T. M., Orsini, L., Kim, W. R. & Roberts, L. R., Feb 2012, In : Clinical Gastroenterology and Hepatology. 10, 2, p. 204-205 2 p.

Research output: Contribution to journalArticle

Reply

Yang, J. D., Harmsen, W. S., Slettedahl, S. W., Enders, F. T., Therneau, T. M., Orsini, L., Kim, W. R. & Roberts, L. R., Feb 2012, In : Clinical Gastroenterology and Hepatology. 10, 2, p. 205-206 2 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Silencing of HSulf-2 expression in MCF10DCIS.com cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo

Khurana, A., McKean, H., Kim, H., Kim, S. H., Mcguire, J., Roberts, L. R., Goetz, M. P. & Shridhar, V., Mar 12 2012, In : Breast Cancer Research. 14, 2, R43.

Research output: Contribution to journalArticle

Ductal Carcinoma
Carcinoma, Intraductal, Noninfiltrating
Heterografts
Breast
Breast Neoplasms
36 Citations (Scopus)

Silencing of miR-370 in Human Cholangiocarcinoma by Allelic Loss and Interleukin-6 Induced Maternal to Paternal Epigenotype Switch

An, F., Yamanaka, S., Allen, S., Roberts, L. R., Gores, G. J., Pawlik, T. M., Xie, Q., Ishida, M., Mezey, E., Ferguson-Smith, A. C., Mori, Y. & Selaru, F. M., Oct 22 2012, In : PLoS One. 7, 10, e45606.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Loss of Heterozygosity
MicroRNAs
microRNA
interleukin-6