Lewis Rowland Roberts, MB, ChB, PhD

  • 16866 Citations
  • 70 Scopus h-Index
1991 …2020
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Research Output 1991 2019

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Article
2017
15 Citations (Scopus)

The present and future disease burden of hepatitis C virus infections with today's treatment paradigm: Volume 4

Chan, H. L. Y., Chen, C. J., Omede, O., Al Qamish, J., Al Naamani, K., Bane, A., Tan, S. S., Simonova, M., Cardenas, I., Derbala, M., Akin, O., Phillips, R. O., Abdelmageed, M. K., Abdulla, M., Adda, D., Al Baqali, A., Al Dweik, N., Al Ejji, K., Al ghazzawi, I., Al Kaabi, S. & 109 others, Al Sadadi, M., Al Salman, J., AlBadri, M., Al-Busafi, S. A., Al-Romaihi, H. E., Ampofo, W., Antonov, K., Anyaike, C., Arome, F., Blach, S., Borodo, M. M., Brandon, S. M., Bright, B., Butt, M. T., Chen, D. S., Chen, P. J., Chien, R. N., Chuang, W. L., Cuellar, D., Elbardiny, A. A., Estes, C., Farag, E., Fung, J., Gamkrelidze, I., Garcia, V., Genov, J., Ghandour, Z., Ghuloom, M., Gomez, B., Gunter, J., Habeeb, J., Hajelssedig, O., Hamoudi, W., Himatt, S. M., Hrstic, I., Hu, C. C., Huang, C. F., Hui, Y. T., Jahis, R., Jelev, D., John, A. K., Kaliaskarova, K. S., Kamel, Y., Kao, J. H., Khamis, J., Khattabi, H., Khoudri, I., Konysbekova, A., Kotzev, I., Lai, M. S., Lao, W. C., Layden, J., Lee, M. H., Lesi, O., Li, M., Lo, A., Loo, C. K., Lukšić, B., Maaroufi, A., Malu, A. O., Mateva, L., Mitova, R., Mohamed, R., Morović, M., Murphy, K., Mustapha, B., Nersesov, A., Ngige, E., Njouom, R., Njoya, O., Nonković, D., Obekpa, S., Oguche, S., Okolo, E. E., Omuemu, C., Ondoa, P., Opare-Sem, O., Owusu-Ofori, S., Prokopenko, Y. N., Razavi, H., Razavi-Shearer, D., Razavi-Shearer, K., Redae, B., Reic, T., Rinke de Wit, T., Rios, C., Robbins, S., Roberts, L. R., Sanad, S. J., Schmelzer, J. D., Sharma, M., Su, T. H., Sultan, K., Tchernev, K., Tsang, O. T. Y., Tsang, S., Tzeuton, C., Ugoeze, S., Uzochukwu, B., Vi, R., Vince, A., Wani, H. U., Wong, V. W. S., Workneh, A., Yacoub, R., Yesmembetov, K. I., Youbi, M., Yuen, M. F. & Nde, H., Oct 1 2017, In : Journal of Viral Hepatitis. 24, p. 25-43 19 p.

Research output: Contribution to journalArticle

Qatar
Virus Diseases
Hepacivirus
Morbidity
Jordan
17 Citations (Scopus)

Transcriptional Induction of Periostin by a Sulfatase 2-TGFb1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma

Chen, G., Nakamura, I., Dhanasekaran, R., Iguchi, E., Tolosa, E. J., Romecin, P. A., Vera, R. E., Almada, L. L., Miamen, A. G., Chaiteerakij, R., Zhou, M., Asiedu, M. K., Moser, C. D., Han, S., Hu, C., Banini, B. A., Oseini, A. M., Chen, Y., Fang, Y., Yang, D. & 10 others, Shaleh, H. M., Wang, S., Wu, D., Song, T., Lee, J. S., Thorgeirsson, S. S., Chevet, E., Shah, V., Fernandez-Zapico, M. E. & Roberts, L. R., Feb 1 2017, In : Cancer Research. 77, 3, p. 632-645 14 p.

Research output: Contribution to journalArticle

Sulfatases
Hepatocellular Carcinoma
Neoplasms
Diethylnitrosamine
Extracellular Matrix Proteins
1 Citation (Scopus)

Venous invasion by hepatic tumors: imaging appearance and implications for management

Thompson, S. M., Wells, M., Andrews, J. C., Ehman, E., Menias, C. O., Hallemeier, C., Roberts, L. R. & Venkatesh, S. K., Sep 19 2017, (Accepted/In press) In : Abdominal Radiology. p. 1-21 21 p.

Research output: Contribution to journalArticle

Liver
Thrombosis
Neoplasms
Multimodal Imaging
Therapeutics
2016
9 Citations (Scopus)

A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice

Koh, M. Y., Gagea, M., Sargis, T., Lemos, R., Grandjean, G., Charbono, A., Bekiaris, V., Sedy, J., Kiriakova, G., Liu, X., Roberts, L. R., Ware, C. & Powis, G., May 1 2016, In : Hepatology. 63, 5, p. 1576-1591 16 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Hypoxia-Inducible Factor 1
Hepatocellular Carcinoma
T-Lymphocytes
Liver
10 Citations (Scopus)

Anti-invasion and anti-migration effects of miR-199a-3p in hepatocellular carcinoma are due in part to targeting CD151

Kim, J. H., Badawi, M., Park, J. K., Jiang, J., Mo, X., Roberts, L. R. & Schmittgen, T. D., Nov 1 2016, In : International Journal of Oncology. 49, 5, p. 2037-2045 9 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Proteins
Messenger RNA
Luciferases
Small Interfering RNA
30 Citations (Scopus)

Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein

Wang, Y., Ding, X., Wang, S., Moser, C. D., Shaleh, H. M., Mohamed, E. A., Chaiteerakij, R., Allotey, L. K., Chen, G., Miyabe, K., McNulty, M. S., Ndzengue, A., Barr Fritcher, E. G., Knudson, R. A., Greipp, P. T., Clark, K. J., Torbenson, M., Kipp, B. R., Zhou, J., Barrett, M. & 4 others, Gustafson, M., Alberts, S. R., Borad, M. J. & Roberts, L. R., Sep 28 2016, In : Cancer Letters. 380, 1, p. 163-173 11 p.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 2
Cholangiocarcinoma
Heterografts
Proteins
Neoplasms
17 Citations (Scopus)

Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells

Ding, X., Chaiteerakij, R., Moser, C. D., Shaleh, H., Boakye, J., Chen, G., Ndzengue, A., Li, Y., Zhou, Y., Huang, S., Sinicrope, F. A., Zou, X., Thomas, M. B., Smith, C. D. & Roberts, L. R., Apr 12 2016, In : Oncotarget. 7, 15, p. 20080-20092 13 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Autophagy
Phosphorylation
Cell Proliferation
Apoptosis
32 Citations (Scopus)

Aspirin use and the risk of cholangiocarcinoma

Choi, J., Ghoz, H. M., Peeraphatdit, T., Baichoo, E., Addissie, B. D., Harmsen, W. S., Therneau, T. M., Olson, J. E., Chaiteerakij, R. & Roberts, L. R., 2016, In : Hepatology. 64, 3, p. 785-796 12 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Aspirin
Confidence Intervals
Odds Ratio
Sclerosing Cholangitis
1 Citation (Scopus)

Biomarkers for hepatocellular carcinoma

Roberts, L. R., 2016, In : Clinical Advances in Hematology and Oncology. 14, 4, p. 223-226 4 p.

Research output: Contribution to journalArticle

X Ray Computed Tomography
alpha-Fetoproteins
Liver Neoplasms
Tumor Biomarkers
Hepatocellular Carcinoma
4 Citations (Scopus)

Biomarkers for hepatocellular carcinoma

Roberts, L. R., Apr 1 2016, In : Gastroenterology and Hepatology. 12, 4, p. 252-255 4 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Biomarkers
21 Citations (Scopus)

Clinical implications of basic research in hepatocellular carcinoma

Dhanasekaran, R., Venkatesh, S. K., Torbenson, M. & Roberts, L. R., Mar 1 2016, In : Journal of Hepatology. 64, 3, p. 736-745 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Research
Liver
Biomarkers
International Normalized Ratio
11 Citations (Scopus)

Determination of hepatitis B phenotype using biochemical and serological markers

Di Bisceglie, A. M., Lombardero, M., Teckman, J., Roberts, L. R., Janssen, H. L. A., Belle, S. H. & Hoofnagle, J. H., 2016, (Accepted/In press) In : Journal of Viral Hepatitis.

Research output: Contribution to journalArticle

Hepatitis B
Chronic Hepatitis B
Biomarkers
Phenotype
Hepatitis B e Antigens
24 Citations (Scopus)

Diabetes Mellitus Heightens the Risk of Hepatocellular Carcinoma Except in Patients With Hepatitis C Cirrhosis

Yang, J. D., Mohamed, H. A., Cvinar, J. L., Gores, G. J., Roberts, L. R. & Kim, W. R., Aug 16 2016, (Accepted/In press) In : American Journal of Gastroenterology.

Research output: Contribution to journalArticle

Hepatitis C
Hepatocellular Carcinoma
Diabetes Mellitus
Fibrosis
Hepacivirus
85 Citations (Scopus)

Direct acting antiviral therapy and tumor recurrence after liver transplantation for hepatitis C-associated hepatocellular carcinoma

Yang, J. D., Aqel, B. A., Pungpapong, S., Gores, G. J., Roberts, L. R. & Leise, M. D., 2016, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Hepatitis C
Liver Transplantation
Antiviral Agents
Hepatocellular Carcinoma
Recurrence
Gastroenterology
Hepatocellular Carcinoma
Research
14 Citations (Scopus)

Heat Stress-InducedPI3K/mTORC2-Dependent AKT signaling is a central mediator of hepatocellular carcinoma survival to thermal ablation induced heat stress

Thompson, S. M., Callstrom, M. R., Jondal, D. E., Butters, K. A., Knudsen, B. E., Anderson, J. L., Lien, K. R., Sutor, S. L., Lee, J. S., Thorgeirsson, S. S., Grande, J. P., Roberts, L. R. & Woodrum, D. A., Sep 1 2016, In : PLoS One. 11, 9, e0162634.

Research output: Contribution to journalArticle

hepatoma
Ablation
heat stress
Hepatocellular Carcinoma
Hot Temperature
14 Citations (Scopus)

High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver

Zhou, D., Hlady, R. A., Schafer, M. J., White, T. A., Liu, C., Choi, J. H., Miller, J. D., Roberts, L. R., LeBrasseur, N. K. & Robertson, K. D., Dec 22 2016, (Accepted/In press) In : Epigenetics. p. 1-15 15 p.

Research output: Contribution to journalArticle

High Fat Diet
Diet
Liver
DNA
DNA Methylation
24 Citations (Scopus)

Implications of CA19-9 elevation for survival, staging, and treatment sequencing in intrahepatic cholangiocarcinoma: A national cohort analysis

Bergquist, J. R., Ivanics, T., Storlie, C., Groeschl, R. T., Tee, M. C., Habermann, E. B., Smoot, R. L., Kendrick, M. L., Farnell, M. B., Roberts, L. R., Gores, G. J., Nagorney, D. M. & Truty, M., Sep 15 2016, In : Journal of Surgical Oncology. 114, 4, p. 475-482 8 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Cohort Studies
Survival
Therapeutics
Reference Values
4 Citations (Scopus)

Increased Prevalence of Metabolic Risk Factors in Asian Americans With Hepatocellular Carcinoma

Kutsenko, A., Ladenheim, M. R., Kim, N., Nguyen, P., Chen, V., Jayasekera, C., Yang, J. D., Kumari, R., Roberts, L. R. & Nguyen, M. H., Sep 15 2016, (Accepted/In press) In : Journal of Clinical Gastroenterology.

Research output: Contribution to journalArticle

Asian Americans
Hepatocellular Carcinoma
Type 2 Diabetes Mellitus
Body Mass Index
Hypertension
5 Citations (Scopus)

Khat chewing and cirrhosis in Somaliland: Case series

Mahamoud, H. D., Muse, S. M., Roberts, L. R., Fischer, P. R., Torbenson, M. & Fader, T., Jul 28 2016, In : African journal of primary health care & family medicine. 8, 1, p. e1-e4

Research output: Contribution to journalArticle

Catha
Mastication
Fibrosis
Yemen
Eastern Africa
4 Citations (Scopus)

Metformin does not improve survival of cholangiocarcinoma patients with diabetes

Yang, Z., Zhang, X., Roberts, R. O., Roberts, L. R. & Chaiteerakij, R., Feb 1 2016, In : Hepatology. 63, 2, p. 667-668 2 p.

Research output: Contribution to journalArticle

Bile Duct Neoplasms
Cholangiocarcinoma
Metformin
Diabetes Complications
Treatment Failure
38 Citations (Scopus)

Metformin use and survival of patients with pancreatic cancer: A cautionary lesson

Chaiteerakij, R., Petersen, G. M., Bamlet, W. R., Chaffee, K. G., Zhen, D. B., Burch, P. A., Leof, E. R., Roberts, L. R. & Oberg, A. L., Jun 1 2016, In : Journal of Clinical Oncology. 34, 16, p. 1898-1904 7 p.

Research output: Contribution to journalArticle

Metformin
Pancreatic Neoplasms
Survival
Adenocarcinoma
Proportional Hazards Models
10 Citations (Scopus)

Novel Deleterious Dihydropyrimidine Dehydrogenase Variants May Contribute to 5-Fluorouracil Sensitivity in an East African Population

Elraiyah, T., Jerde, C. R., Shrestha, S., Wu, R., Nie, Q., Giama, N. H., Sarangi, V., Roberts, L. R., Offer, S. M. & Diasio, R. B., 2016, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Dihydrouracil Dehydrogenase (NADP)
Fluorouracil
Population
Pharmacogenetics
Haplotypes
68 Citations (Scopus)

p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer

Duran, A., Hernandez, E. D., Reina-Campos, M., Castilla, E. A., Subramaniam, S., Raghunandan, S., Roberts, L. R., Kisseleva, T., Karin, M., Diaz-Meco, M. T. & Moscat, J., Oct 10 2016, In : Cancer Cell. 30, 4, p. 595-609 15 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Calcitriol Receptors
Liver Neoplasms
Fibrosis
Hepatocellular Carcinoma
5 Citations (Scopus)
Hepatocellular Carcinoma
Maximum Tolerated Dose
Neoplasms
Therapeutics
Hypophosphatemia
6 Citations (Scopus)

Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated with Liver Cirrhosis and Hepatocellular Carcinoma

Blackburn, P. R., Hickey, R., Nace, R. A., Giama, N. H., Kraft, D. L., Bordner, A. J., Chaiteerakij, R., McCormick, J. B., Radulovic, M., Graham, R., Torbenson, M., Tortorelli, S., Scott, C. R., Lindor, N. M., Milliner, D. S., Oglesbee, D., Al-Qabandi, W., Grompe, M., Gavrilov, D. K., El-Youssef, M. & 5 others, Clark, K. J., Atwal, P. S., Roberts, L. R., Klee, E. W. & Ekker, S. C., Oct 1 2016, In : Human Mutation. 37, 10, p. 1097-1105 9 p.

Research output: Contribution to journalArticle

Tyrosinemias
Liver Cirrhosis
Tyrosine
Hepatocellular Carcinoma
Fibrosis
2015
22 Citations (Scopus)

Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma

Dhanasekaran, R., Nakamura, I., Hu, C., Chen, G., Oseini, A. M., Seven, E. S., Miamen, A. G., Moser, C. D., Zhou, W., van Kuppevelt, T. H., Van Deursen, J., Mounajjed, T., Fernandez-Zapico, M. E. & Roberts, L. R., Apr 1 2015, In : Hepatology. 61, 4, p. 1269-1283 15 p.

Research output: Contribution to journalArticle

Sulfatases
Transforming Growth Factors
Hepatocellular Carcinoma
Neoplasms
Transgenic Mice
35 Citations (Scopus)

An Optimized Set of Fluorescence in Situ Hybridization Probes for Detection of Pancreatobiliary Tract Cancer in Cytology Brush Samples

Barr Fritcher, E. G., Voss, J. S., Brankley, S. M., Campion, M. B., Jenkins, S. M., Keeney, M. E., Henry, M. R., Kerr, S. M., Chaiteerakij, R., Pestova, E. V., Clayton, A. C., Zhang, J., Roberts, L. R., Gores, G. J., Halling, K. C. & Kipp, B. R., Dec 1 2015, In : Gastroenterology. 149, 7, p. 1813-1824e1

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Cell Biology
Neoplasms
Sclerosing Cholangitis
Clinical Pathology
4 Citations (Scopus)

Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma

Chaiteerakij, R., Juran, B. D., Aboelsoud, M. M., Harmsen, W. S., Moser, C. D., Giama, N. H., Allotey, L. K., Mettler, T. A., Baichoo, E., Zhang, X., Therneau, T. M., Lazaridis, K. N. & Roberts, L. R., Oct 1 2015, In : Cancer Medicine. 4, 10, p. 1599-1602 4 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Neoplasm Genes
Inflammation
Survival
Single Nucleotide Polymorphism
16 Citations (Scopus)

Biphenotypic hepatic tumors: imaging findings and review of literature

Wells, M., Venkatesh, S. K., Chandan, V. S., Fidler, J. L., Fletcher, J. G., Johnson, G. B., Hough, D. M. & Roberts, L. R., May 8 2015, (Accepted/In press) In : Abdominal Imaging.

Research output: Contribution to journalArticle

Tumor Biomarkers
Liver
Neoplasms
Cholangiocarcinoma
Hepatocellular Carcinoma
38 Citations (Scopus)

Characteristics of adults in the hepatitis b research network in North America reflect their country of origin and hepatitis B virus genotype

for the Hepatitis B Research Network & Kim, W. R., Jan 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 1, p. 183-192 10 p.

Research output: Contribution to journalArticle

North America
Hepatitis B
Hepatitis B virus
Hepatitis
Genotype
25 Citations (Scopus)

Circulating tumor cells are associated with poor overall survival in patients with cholangiocarcinoma

Yang, J. D., Campion, M. B., Liu, M. C., Chaiteerakij, R., Giama, N. H., Ahmed Mohammed, H., Zhang, X., Hu, C., Campion, V. L., Jen, J., Venkatesh, S. K., Halling, K. C., Kipp, B. R. & Roberts, L. R., 2015, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Cholangiocarcinoma
Survival
Confidence Intervals
Klatskin Tumor
10 Citations (Scopus)

Classification and Staging of Hepatocellular Carcinoma: An Aid to Clinical Decision-Making

Addissie, B. D. & Roberts, L. R., May 1 2015, In : Clinics in Liver Disease. 19, 2, p. 277-294 18 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Patient Selection
Clinical Decision-Making
Therapeutics
34 Citations (Scopus)

Combinations of biomarkers and Milan criteria for predicting hepatocellular carcinoma recurrence after liver transplantation

Chaiteerakij, R., Zhang, X., Addissie, B. D., Mohamed, E. A., Harmsen, W. S., Theobald, P. J., Peters, B. E., Balsanek, J. G., Ward, M. M., Giama, N. H., Moser, C. D., Oseini, A. M., Umeda, N., Venkatesh, S. K., Harnois, D., Charlton, M. R., Yamada, H., Satomura, S., Algeciras-Schimnich, A., Snyder, M. R. & 2 others, Therneau, T. M. & Roberts, L. R., May 1 2015, In : Liver Transplantation. 21, 5, p. 599-606 8 p.

Research output: Contribution to journalArticle

alpha-Fetoproteins
Liver Transplantation
Hepatocellular Carcinoma
Biomarkers
Recurrence
1 Citation (Scopus)

Correction: Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling

Nakamura, I., Zakharia, K., Banini, B. A., Mikhail, D. S., Kim, T. H., Yang, J. D., Moser, C. D., Shaleh, H. M., Thornburgh, S. R., Walters, I. & Roberts, L. R., Nov 3 2015, In : PLoS One. 10, 11, e0142355.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Chemical activation
brivanib
15 Citations (Scopus)

Diabetes and prediabetes in patients with hepatitis B residing in North America

HBRN & Kim, W. R., Nov 1 2015, In : Hepatology. 62, 5, p. 1364-1374 11 p.

Research output: Contribution to journalArticle

Prediabetic State
North America
Hepatitis B
Odds Ratio
Fasting
56 Citations (Scopus)

DNAJB1-PRKACA is specific for fibrolamellar carcinoma

Graham, R., Jin, L., Knutson, D. L., Kloft-Nelson, S. M., Greipp, P. T., Waldburger, N., Roessler, S., Longerich, T., Roberts, L. R., Oliveira, A. M., Halling, K. C., Schirmacher, P. & Torbenson, M., Jun 1 2015, In : Modern Pathology. 28, 6, p. 822-829 8 p.

Research output: Contribution to journalArticle

Carcinoma
Hepatocellular Carcinoma
Scirrhous Adenocarcinoma
Polymerase Chain Reaction
In Situ Hybridization
1 Citation (Scopus)

Ectopic Gallbladder

Guerin, J. B., Venkatesh, S. K. & Roberts, L. R., Jul 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 7, p. e69

Research output: Contribution to journalArticle

Abdominal Radiography
Gallbladder Diseases
Choristoma
Gallbladder
Magnetic Resonance Imaging
86 Citations (Scopus)

Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

Nath, A., Li, I., Roberts, L. R. & Chan, C., Oct 1 2015, In : Scientific Reports. 5, 14752.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Nonesterified Fatty Acids
Hepatocellular Carcinoma
Wnt Signaling Pathway
Liver Neoplasms
13 Citations (Scopus)
Receptor, Fibroblast Growth Factor, Type 2
Cholangiocarcinoma
Fibroblast Growth Factors
Therapeutics
13 Citations (Scopus)

Fluorescence in situ hybridization compared with conventional cytology for the diagnosis of malignant biliary tract strictures in Asian patients

Chaiteerakij, R., Barr Fritcher, E. G., Angsuwatcharakon, P., Ridtitid, W., Chaithongrat, S., Leerapun, A., Baron, T. H., Kipp, B. R., Henry, M. R., Halling, K. C., Rerknimitr, R. & Roberts, L. R., Mar 23 2015, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Biliary Tract
Fluorescence In Situ Hybridization
Cell Biology
Pathologic Constriction
Bile Ducts
226 Citations (Scopus)

Global patterns of hepatocellular carcinoma management from diagnosis to death: The BRIDGE Study

Park, J. W., Chen, M., Colombo, M., Roberts, L. R., Schwartz, M., Chen, P. J., Kudo, M., Johnson, P., Wagner, S., Orsini, L. S. & Sherman, M., Sep 1 2015, In : Liver International. 35, 9, p. 2155-2166 12 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
North America
Republic of Korea
Taiwan
China
24 Citations (Scopus)

Hepatocellular carcinoma occurs at an earlier age in Africans, particularly in association with chronic Hepatitis B

Yang, J. D., Gyedu, A., Afihene, M. Y., Duduyemi, B. M., Micah, E., Kingham, T. P., Nyirenda, M., Nkansah, A. A., Bandoh, S., Duguru, M. J., Okeke, E. N., Kouakou-Lohoues, M. J., Abdo, A., Awuku, Y. A., Ajayi, A. O., Omonisi, A. E., Ocama, P., Malu, A. O., Mustapha, S., Okonkwo, U. & 6 others, Kooffreh-Ada, M., Debes, J., Onyekwere, C., Ekere, F., Rufina, I. & Roberts, L. R., Nov 1 2015, In : American Journal of Gastroenterology. 110, 11, p. 1629-1631 3 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma

Gai, X., Tu, K., Li, C., Lu, Z., Roberts, L. R. & Zheng, X., Apr 9 2015, In : Cell Death and Disease. 6, 4, e1712.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Hepatocellular Carcinoma
Apoptosis
Fluorouracil
p300-CBP-associated factor
23 Citations (Scopus)

Integration of extracellular RNA profiling data using metadata, biomedical ontologies and Linked Data technologies

Subramanian, S. L., Kitchen, R. R., Alexander, R., Carter, B. S., Cheung, K. H., Laurent, L. C., Pico, A., Roberts, L. R., Roth, M. E., Rozowsky, J. S., Su, A. I., Gerstein, M. B. & Milosavljevic, A., Jan 1 2015, In : Journal of Extracellular Vesicles. 4, 1, 27497.

Research output: Contribution to journalArticle

Biological Ontologies
Atlases
RNA
Technology
Information Storage and Retrieval
4 Citations (Scopus)

Prognostic Value of Model for End-Stage Liver Disease Score Measurements on a Daily Basis in Critically Ill Patients with Cirrhosis

Peeraphatdit, T., Naksuk, N., Thongprayoon, C., Harmsen, W. S., Therneau, T. M., Ricci, P., Roberts, L. R. & Chaiteerakij, R., Sep 1 2015, In : Mayo Clinic Proceedings. 90, 9, p. 1196-1206 11 p.

Research output: Contribution to journalArticle

End Stage Liver Disease
Critical Illness
Fibrosis
Intensive Care Units
Mortality
6 Citations (Scopus)

Screening for hepatocellular carcinoma and cholangiocarcinoma: Can biomarkers replace imaging?

Lozada, M. E., Chaiteerakij, R. & Roberts, L. R., Jun 1 2015, In : Current Hepatitis Reports. 14, 2, p. 128-138 11 p., A004.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Hepatocellular Carcinoma
Biomarkers
Biliary Tract Neoplasms
Survival
125 Citations (Scopus)

The role of hepatic resection in the treatment of hepatocellular cancer

Roayaie, S., Jibara, G., Tabrizian, P., Park, J. W., Yang, J., Yan, L., Schwartz, M., Han, G., Izzo, F., Chen, M., Blanc, J. F., Johnson, P., Kudo, M., Roberts, L. R. & Sherman, M., Aug 1 2015, In : Hepatology. 62, 2, p. 440-451 12 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Liver
Portal Hypertension
Guidelines
Bilirubin
50 Citations (Scopus)

Unique genomic profile of fibrolamellar hepatocellular carcinoma

Cornella, H., Alsinet, C., Sayols, S., Zhang, Z., Hao, K., Cabellos, L., Hoshida, Y., Villanueva, A., Thung, S., Ward, S. C., Rodriguez-Carunchio, L., Vila-Casadesús, M., Imbeaud, S., Lachenmayer, A., Quaglia, A., Nagorney, D. M., Minguez, B., Carrilho, F., Roberts, L. R., Waxman, S. & 6 others, Mazzaferro, V., Schwartz, M., Esteller, M., Heaton, N. D., Zucman-Rossi, J. & Llovet, J. M., Apr 1 2015, In : Gastroenterology. 148, 4, p. 806-818.e10

Research output: Contribution to journalArticle

Liver Neoplasms
Transcriptome
Gene Expression
Mutation
Chromosome Aberrations
65 Citations (Scopus)

Update on Biomarkers of Hepatocellular Carcinoma

Chaiteerakij, R., Addissie, B. D. & Roberts, L. R., 2015, In : Clinical Gastroenterology and Hepatology. 13, 2, p. 237-245 9 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Biomarkers
Metabolomics
Tumor Biomarkers
Proteomics