Lewis Rowland Roberts, MB, ChB, PhD

  • 17074 Citations
  • 71 Scopus h-Index
1991 …2020
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Research Output 1991 2019

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Article
2018
11 Citations (Scopus)

Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2

Kostallari, E., Hirsova, P., Prasnicka, A., Verma, V. K., Yaqoob, U., Wongjarupong, N., Roberts, L. R. & Shah, V., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor alpha Receptor
Hepatic Stellate Cells
Liver Cirrhosis
src Homology Domains
Phosphoric Monoester Hydrolases
1 Citation (Scopus)
Gene transfer
Horizontal Gene Transfer
Workflow
Sequencing
Work Flow
2 Citations (Scopus)

Hypothyroidism is associated with worse outcomes of hepatocellular carcinoma patients after liver transplantation

Zhang, N., Jin, W., Zhou, S., Yang, J. D., Harmsen, W. S., Giama, N. H., Wongjarupong, N., Heimbach, J. K., Watt, K. D., Malhi, H. M., Therneau, T. M. & Roberts, L. R., Jan 1 2018, (Accepted/In press) In : Cancer Medicine.

Research output: Contribution to journalArticle

Hypothyroidism
Liver Transplantation
Hepatocellular Carcinoma
Survival
Recurrence
13 Citations (Scopus)

Impact of surveillance for hepatocellular carcinoma on survival in patients with compensated cirrhosis

Yang, J. D., Mannalithara, A., Piscitello, A. J., Kisiel, J. B., Gores, G. J., Roberts, L. R. & Kim, W. R., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Fibrosis
Survival
Liver
Mortality

Insights into the interplay between KIR gene frequencies and chronic HBV infection in Burkina Faso

Sorgho, P. A., Martinson, J. J., Djigma, F. W., Yonli, A. T., Nagalo, B., Compaore, T. R., Obiri-Yeboah, D., Diarra, B., Sombie, H. K., Zongo, A. W., Ouattara, A. K., Soubeiga, S. T. R., Traore, L., Roberts, L. R. & Simpore, J., Jan 1 2018, In : Mediterranean Journal of Hematology and Infectious Diseases. 10, 1, e2018060.

Research output: Contribution to journalArticle

Open Access
KIR Receptors
Burkina Faso
Chronic Hepatitis B
Virus Diseases
Hepatitis B virus
17 Citations (Scopus)

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 213-226.e3

Research output: Contribution to journalArticle

Ubiquitin
Genes
Neoplasms
Tumors
Amplification
2 Citations (Scopus)
Yttrium
Microspheres
Glass
Hepatocellular Carcinoma
Randomized Controlled Trials
103 Citations (Scopus)

lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 706-720.e9

Research output: Contribution to journalArticle

Long Noncoding RNA
Epigenomics
Cell Cycle
Genes
Neoplasms
21 Citations (Scopus)

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 172-180.e3

Research output: Contribution to journalArticle

Atlases
Learning systems
Tumors
Genes
Chemical activation
101 Citations (Scopus)

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 338-354.e15

Research output: Contribution to journalArticle

Learning systems
Tumors
Neoplasms
Stem cells
Logistics
22 Citations (Scopus)

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 255-269.e4

Research output: Contribution to journalArticle

Tumors
Carbohydrates
Oncology
Metabolism
Vitamins
14 Citations (Scopus)

Molecular testing for the clinical diagnosis of fibrolamellar carcinoma

Graham, R., Yeh, M. M., Lam-Himlin, D., Roberts, L. R., Terracciano, L., Cruise, M. W., Greipp, P. T., Zreik, R. T., Jain, D., Zaid, N., Salaria, S. N., Jin, L., Wang, X., Rustin, J. G., Kerr, S. E., Sukov, W. R., Solomon, D. A., Kakar, S., Waterhouse, E., Gill, R. M. & 8 others, Ferrell, L., Alves, V. A., Nart, D., Yilmaz, F., Roessler, S., Longerich, T., Schirmacher, P. & Torbenson, M., Jan 1 2018, In : Modern Pathology. 31, 1, p. 141-149 9 p.

Research output: Contribution to journalArticle

Carcinoma
Fluorescence In Situ Hybridization
Gene Fusion
Keratin-7
Gene Amplification
5 Citations (Scopus)

Non-alcoholic fatty liver disease-associated hepatocellular carcinoma: Effect of hepatic steatosis on major hepatocellular carcinoma features at MRI

Thompson, S. M., Garg, I., Ehman, E., Sheedy, S. P., Bookwalter, C. A., Carter, R. E., Roberts, L. R. & Venkatesh, S. K., Jan 1 2018, In : British Journal of Radiology. 91, 1092, 20180345.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Liver
Capsules
Fats
Non-alcoholic Fatty Liver Disease
242 Citations (Scopus)

Oncogenic Signaling Pathways in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 321-337.e10

Research output: Contribution to journalArticle

Atlases
Tumors
Genes
Genome
Neoplasms
37 Citations (Scopus)

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

The Cancer Genome Atlas Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 282-300.e2

Research output: Contribution to journalArticle

Atlases
Oncogenes
Genome
Neoplasms
Neoplasm Genes
70 Citations (Scopus)

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 297-312.e12

Research output: Contribution to journalArticle

Long Noncoding RNA
Neoplasm Genes
Tumors
Genes
Neoplasms
97 Citations (Scopus)

Pathogenic Germline Variants in 10,389 Adult Cancers

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 355-370.e14

Research output: Contribution to journalArticle

Gene expression
Automatic teller machines
Tumors
Neoplasms
Genes
54 Citations (Scopus)

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 305-320.e10

Research output: Contribution to journalArticle

Genomics
Tumors
Genes
Neoplasms
Atlases
4 Citations (Scopus)

Prevalent hepatitis B surface antigen among first-time blood donors in Gabon

Eko Mba, J. M., Bisseye, C., Ntsame Ndong, J. M., Mombo, L. E., Bengone, C., Migolet, G. M., Batchi, B. M., Kosiorek, H. E., Butterfield, R. J., Roberts, L. R., Borad, M. J. & Nagalo, B., Apr 1 2018, In : PLoS One. 13, 4, e0194285.

Research output: Contribution to journalArticle

Gabon
Seroepidemiologic Studies
Hepatitis B Surface Antigens
Blood Donors
seroprevalence
74 Citations (Scopus)

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

MC3 Working Group & The Cancer Genome Atlas Research Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 271-281.e7

Research output: Contribution to journalArticle

Exome
Mutation
Atlases
Neoplasms
Genomics
50 Citations (Scopus)

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 282-296.e4

Research output: Contribution to journalArticle

Genes
Mutation
Neoplasms
Tumors
RNA
73 Citations (Scopus)

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 181-193.e7

Research output: Contribution to journalArticle

Tumor-Infiltrating Lymphocytes
Lymphocytes
Pathology
Tumors
Learning
34 Citations (Scopus)

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 270-281.e3

Research output: Contribution to journalArticle

Tumors
Mutation
Neoplasms
Bioelectric potentials
Bioinformatics
76 Citations (Scopus)

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 313-326.e5

Research output: Contribution to journalArticle

Atlases
Renal Cell Carcinoma
Genes
Cells
Genome
343 Citations (Scopus)

The Immune Landscape of Cancer

The Cancer Genome Atlas Research Network, Apr 17 2018, In : Immunity. 48, 4, p. 812-830.e14

Research output: Contribution to journalArticle

Neoplasms
Genetic Epigenesis
Lymphocytes
Th2 Cells
Th1 Cells
2017
30 Citations (Scopus)

Characteristics, management, and outcomes of patients with hepatocellular carcinoma in Africa: a multicountry observational study from the Africa Liver Cancer Consortium

Yang, J. D., Mohamed, E. A., Aziz, A. O. A., Shousha, H. I., Hashem, M. B., Nabeel, M. M., Abdelmaksoud, A. H., Elbaz, T. M., Afihene, M. Y., Duduyemi, B. M., Ayawin, J. P., Gyedu, A., Lohouès-Kouacou, M. J., Ndam, A. W. N., Moustafa, E. F., Hassany, S. M., Moussa, A. M., Ugiagbe, R. A., Omuemu, C. E., Anthony, R. & 37 others, Palmer, D., Nyanga, A. F., Malu, A. O., Obekpa, S., Abdo, A. E., Siddig, A. I., Mudawi, H. M. Y., Okonkwo, U., Kooffreh-Ada, M., Awuku, Y. A., Nartey, Y. A., Abbew, E. T., Awuku, N. A., Otegbayo, J. A., Akande, K. O., Desalegn, H. M., Omonisi, A. E., Ajayi, A. O., Okeke, E. N., Duguru, M. J., Davwar, P. M., Okorie, M. C., Mustapha, S., Debes, J. D., Ocama, P., Lesi, O. A., Odeghe, E., Bello, R., Onyekwere, C., Ekere, F., Igetei, R., Mah'moud, M. A., Addissie, B., Ali, H. M., Gores, G. J., Topazian, M. & Roberts, L. R., Feb 1 2017, In : The Lancet Gastroenterology and Hepatology. 2, 2, p. 103-111 9 p.

Research output: Contribution to journalArticle

Egypt
Liver Neoplasms
Observational Studies
Hepatocellular Carcinoma
Cote d'Ivoire
2 Citations (Scopus)

Characteristics of US-Born Versus Foreign-Born Americans of African Descent with Chronic Hepatitis B

Hassan, M. A., Kim, W. R., Li, R., Smith, C. I., Fried, M. W., Sterling, R. K., Ghany, M. G., Wahed, A. S., Ganova-Raeva, L. M., Roberts, L. R. & Lok, A. S. F., Aug 1 2017, In : American Journal of Epidemiology. 186, 3, p. 356-366 11 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
African Americans
Hepatitis B virus
Virus Diseases
Genotype
5 Citations (Scopus)

Clinical, Biochemical, and Histopathology Features of Patients With Glycogenic Hepatopathy

Mukewar, S., Sharma, A., Lackore, K. A., Enders, F. T., Torbenson, M., Kamath, P. S., Roberts, L. R. & Kudva, Y. C., Jun 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 6, p. 927-933 7 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Diabetic Ketoacidosis
Pediatrics
Hepatomegaly
Liver
350 Citations (Scopus)

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

The Cancer Genome Atlas Research Network & Chandan, V. S., Jun 15 2017, In : Cell. 169, 7, p. 1327-1341.e23

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Genes
DNA
MicroRNAs
Gene expression
9 Citations (Scopus)
Liver Neoplasms
Radiotherapy
Immunotherapy
Population
Cell Count
7 Citations (Scopus)

Early Age Hepatocellular Carcinoma Associated With Hepatitis B Infection in South America

Chan, A. J., Balderramo, D., Kikuchi, L., Ballerga, E. G., Prieto, J. E., Tapias, M., Idrovo, V., Davalos, M. B., Cairo, F., Barreyro, F. J., Paredes, S., Hernandez, N., Avendaño, K., Ferrer, J. D., Yang, J. D., Carrera, E., Mattos, A. Z., Hirsch, B. S., Gonçalves, P. T., Carrilho, F. J. & 2 others, Roberts, L. R. & Debes, J. D., 2017, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Factors Influencing Surveillance for Hepatocellular Carcinoma in Patients with Liver Cirrhosis

Ahmed Mohammed, H. A., Yang, J. D., Giama, N. H., Choi, J., Ali, H. M., Mara, K. C., Harmsen, W. S., Wiesner, R. H., Leise, M. D., Therneau, T. M. & Roberts, L. R., Feb 1 2017, In : Liver Cancer. 6, 2, p. 126-136 11 p.

Research output: Contribution to journalArticle

Open Access
Liver Cirrhosis
Hepatocellular Carcinoma
Fibrosis
Primary Health Care
Gastroenterology
621 Citations (Scopus)

Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study

Blach, S., Zeuzem, S., Manns, M., Altraif, I., Duberg, A. S., Muljono, D. H., Waked, I., Alavian, S. M., Lee, M. H., Negro, F., Abaalkhail, F., Abdou, A., Abdulla, M., Rached, A. A., Aho, I., Akarca, U., Al Ghazzawi, I., Al Kaabi, S., Al Lawati, F., Al Namaani, K. & 202 others, Al Serkal, Y., Al-Busafi, S. A., Al-Dabal, L., Aleman, S., Alghamdi, A. S., Aljumah, A. A., Al-Romaihi, H. E., Andersson, M. I., Arendt, V., Arkkila, P., Assiri, A. M., Baatarkhuu, O., Bane, A., Ben-Ari, Z., Bergin, C., Bessone, F., Bihl, F., Bizri, A. R., Blachier, M., Blasco, A. J., Mello, C. E. B., Bruggmann, P., Brunton, C. R., Calinas, F., Chan, H. L. Y., Chaudhry, A., Cheinquer, H., Chen, C. J., Chien, R. N., Choi, M. S., Christensen, P. B., Chuang, W. L., Chulanov, V., Cisneros, L., Clausen, M. R., Cramp, M. E., Craxi, A., Croes, E. A., Dalgard, O., Daruich, J. R., de Ledinghen, V., Dore, G. J., El-Sayed, M. H., Ergör, G., Esmat, G., Estes, C., Falconer, K., Farag, E., Ferraz, M. L. G., Ferreira, P. R., Flisiak, R., Frankova, S., Gamkrelidze, I., Gane, E., García-Samaniego, J., Khan, A. G., Gountas, I., Goldis, A., Gottfredsson, M., Grebely, J., Gschwantler, M., Pessôa, M. G., Gunter, J., Hajarizadeh, B., Hajelssedig, O., Hamid, S., Hamoudi, W., Hatzakis, A., Himatt, S. M., Hofer, H., Hrstic, I., Hui, Y. T., Hunyady, B., Idilman, R., Jafri, W., Jahis, R., Janjua, N. Z., Jarčuška, P., Jeruma, A., Jonasson, J. G., Kamel, Y., Kao, J. H., Kaymakoglu, S., Kershenobich, D., Khamis, J., Kim, Y. S., Kondili, L., Koutoubi, Z., Krajden, M., Krarup, H., Lai, M. S., Laleman, W., Lao, W. C., Lavanchy, D., Lázaro, P., Leleu, H., Lesi, O., Lesmana, L. A., Li, M., Liakina, V., Lim, Y. S., Luksic, B., Mahomed, A., Maimets, M., Makara, M., Malu, A. O., Marinho, R. T., Marotta, P., Mauss, S., Memon, M. S., Correa, M. C. M., Mendez-Sanchez, N., Merat, S., Metwally, A. M., Mohamed, R., Moreno, C., Mourad, F. H., Müllhaupt, B., Murphy, K., Nde, H., Njouom, R., Nonkovic, D., Norris, S., Obekpa, S., Oguche, S., Olafsson, S., Oltman, M., Omede, O., Omuemu, C., Opare-Sem, O., Øvrehus, A. L. H., Owusu-Ofori, S., Oyunsuren, T. S., Papatheodoridis, G., Pasini, K., Peltekian, K. M., Phillips, R. O., Pimenov, N., Poustchi, H., Prabdial-Sing, N., Qureshi, H., Ramji, A., Razavi-Shearer, D., Razavi-Shearer, K., Redae, B., Reesink, H. W., Ridruejo, E., Robbins, S., Roberts, L. R., Roberts, S. K., Rosenberg, W. M., Roudot-Thoraval, F., Ryder, S. D., Safadi, R., Sagalova, O., Salupere, R., Sanai, F. M., Avila, J. F. S., Saraswat, V., Sarmento-Castro, R., Sarrazin, C., Schmelzer, J. D., Schréter, I., Seguin-Devaux, C., Shah, S. R., Sharara, A. I., Sharma, M., Shevaldin, A., Shiha, G. E., Sievert, W., Sonderup, M., Souliotis, K., Speiciene, D., Sperl, J., Stärkel, P., Stauber, R. E., Stedman, C., Struck, D., Su, T. H., Sypsa, V., Tan, S. S., Tanaka, J., Thompson, A. J., Tolmane, I., Tomasiewicz, K., Valantinas, J., Van Damme, P., van der Meer, A. J., van Thiel, I., Van Vlierberghe, H., Vince, A., Vogel, W., Wedemeyer, H., Weis, N., Wong, V. WS., Yaghi, C., Yosry, A., Yuen, M. F., Yunihastuti, E., Yusuf, A., Zuckerman, E. & Razavi, H., Mar 1 2017, In : The Lancet Gastroenterology and Hepatology. 2, 3, p. 161-176 16 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Genotype
Infection
Developed Countries
3 Citations (Scopus)

Heat stress induced, ligand-independent MET and EGFR signalling in hepatocellular carcinoma

Thompson, S. M., Jondal, D. E., Butters, K. A., Knudsen, B. E., Anderson, J. L., Stokes, M. P., Jia, X., Grande, J. P., Roberts, L. R., Callstrom, M. R. & Woodrum, D. A., Nov 6 2017, (Accepted/In press) In : International Journal of Hyperthermia. p. 1-12 12 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Hot Temperature
Ligands
Intercellular Signaling Peptides and Proteins
Phosphorylation
14 Citations (Scopus)

Hepatocellular carcinoma in South America: Evaluation of risk factors, demographics and therapy

Debes, J. D., Chan, A. J., Balderramo, D., Kikuchi, L., Gonzalez Ballerga, E., Prieto, J. E., Tapias, M., Idrovo, V., Davalos, M. B., Cairo, F., Barreyro, F. J., Paredes, S., Hernandez, N., Avendaño, K., Diaz Ferrer, J., Yang, J. D., Carrera, E., Garcia, J. A., Mattos, A. Z., Hirsch, B. S. & 3 others, Gonçalves, P. T., Carrilho, F. J. & Roberts, L. R., 2017, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

South America
Hepatocellular Carcinoma
Demography
Therapeutics
Alcoholic Liver Cirrhosis
38 Citations (Scopus)

Hepatocellular Carcinoma Is the Most Common Indication for Liver Transplantation and Placement on the Waitlist in the United States

Yang, J. D., Larson, J. J., Watt, K. D., Allen, A., Wiesner, R. H., Gores, G. J., Roberts, L. R., Heimbach, J. A. & Leise, M. D., May 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 5, p. 767-775.e3

Research output: Contribution to journalArticle

Liver Transplantation
Hepatocellular Carcinoma
Virus Diseases
Hepacivirus
Transplants
16 Citations (Scopus)

Historical epidemiology of hepatitis C virus in select countries—volume 4

Maaroufi, A., Vince, A., Himatt, S. M., Mohamed, R., Fung, J., Opare-Sem, O., Workneh, A., Njouom, R., Al ghazzawi, I., Abdulla, M., Kaliaskarova, K. S., Owusu-Ofori, S., Abdelmageed, M. K., Adda, D., Akin, O., Al Baqali, A., Al Dweik, N., Al Ejji, K., Al Kaabi, S., Al Naamani, K. & 109 others, Al Qamish, J., Al Sadadi, M., Al Salman, J., AlBadri, M., Al-Busafi, S. A., Al-Romaihi, H. E., Ampofo, W., Antonov, K., Anyaike, C., Arome, F., Bane, A., Blach, S., Borodo, M. M., Brandon, S. M., Bright, B., Butt, M. T., Cardenas, I., Chan, H. L. Y., Chen, C. J., Chen, D. S., Chen, P. J., Chien, R. N., Chuang, W. L., Cuellar, D., Derbala, M., Elbardiny, A. A., Estes, C., Farag, E., Gamkrelidze, I., Garcia, V., Genov, J., Ghandour, Z., Ghuloom, M., Gomez, B., Gunter, J., Habeeb, J., Hajelssedig, O., Hamoudi, W., Hrstic, I., Hu, C. C., Huang, C. F., Hui, Y. T., Jahis, R., Jelev, D., John, A. K., Kamel, Y., Kao, J. H., Khamis, J., Khattabi, H., Khoudri, I., Konysbekova, A., Kotzev, I., Lai, M. S., Lao, W. C., Layden, J., Lee, M. H., Lesi, O., Li, M., Lo, A., Loo, C. K., Lukšić, B., Malu, A. O., Mateva, L., Mitova, R., Morović, M., Murphy, K., Mustapha, B., Nde, H., Nersesov, A., Ngige, E., Njoya, O., Nonković, D., Obekpa, S., Oguche, S., Okolo, E. E., Omede, O., Omuemu, C., Ondoa, P., Phillips, R. O., Prokopenko, Y. N., Razavi, H., Razavi-Shearer, D., Redae, B., Reic, T., Rinke de Wit, T., Rios, C., Robbins, S., Roberts, L. R., Sanad, S. J., Schmelzer, J. D., Sharma, M., Simonova, M., Su, T. H., Sultan, K., Tan, S. S., Tchernev, K., Tsang, O. T. Y., Tsang, S., Tzeuton, C., Ugoeze, S., Uzochukwu, B., Vi, R., Wani, H. U., Wong, V. W. S., Yacoub, R., Yesmembetov, K. I., Youbi, M., Yuen, M. F. & Razavi-Shearer, K., Oct 1 2017, In : Journal of Viral Hepatitis. 24, p. 8-24 17 p.

Research output: Contribution to journalArticle

Hepacivirus
Epidemiology
Taiwan
Transplants
Liver
3 Citations (Scopus)

Identification of fucosylated Fetuin-A as a potential biomarker for cholangiocarcinoma

Betesh, L., Comunale, M. A., Wang, M., Liang, H., Hafner, J., Karabudak, A., Giama, N. H., Moser, C. D., Miyoshi, E., Roberts, L. R., Block, T. M. & Mehta, A., 2017, (Accepted/In press) In : Proteomics - Clinical Applications.

Research output: Contribution to journalArticle

alpha-2-HS-Glycoprotein
Cholangiocarcinoma
Biomarkers
Polysaccharides
Sclerosing Cholangitis
12 Citations (Scopus)

Impact of country of birth on age at the time of diagnosis of hepatocellular carcinoma in the United States

Yang, J. D., Altekruse, S. F., Nguyen, M. H., Gores, G. J. & Roberts, L. R., Jan 1 2017, In : Cancer. 123, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Parturition
Oceania
Odds Ratio
Confidence Intervals
10 Citations (Scopus)

Improved performance of serum alpha-fetoprotein for hepatocellular carcinoma diagnosis in hcv cirrhosis with normal alanine transaminase

Yang, J. D., Dai, J., Singal, A. G., Gopal, P., Addissie, B. D., Nguyen, M. H., Befeler, A. S., Reddy, K. R., Schwartz, M., Harnois, D., Yamada, H., Gores, G. J., Feng, Z., Marrero, J. A. & Roberts, L. R., Jul 1 2017, In : Cancer Epidemiology Biomarkers and Prevention. 26, 7, p. 1085-1092 8 p.

Research output: Contribution to journalArticle

alpha-Fetoproteins
Alanine Transaminase
Hepatocellular Carcinoma
Fibrosis
Hepacivirus
22 Citations (Scopus)

Inhibiting histone deacetylases suppresses glucose metabolism and hepatocellular carcinoma growth by restoring FBP1 expression

Yang, J., Jin, X., Yan, Y., Shao, Y., Pan, Y., Roberts, L. R., Zhang, J., Huang, H. & Jiang, J., Mar 6 2017, In : Scientific Reports. 7, 43864.

Research output: Contribution to journalArticle

Histone Deacetylases
Hepatocellular Carcinoma
Glucose
Growth
Histone Deacetylase 1
11 Citations (Scopus)

Initiation of aberrant DNA methylation patterns and heterogeneity in precancerous lesions of human hepatocellular cancer

Hlady, R. A., Zhou, D., Puszyk, W., Roberts, L. R., Liu, C. & Robertson, K. D., Jan 27 2017, (Accepted/In press) In : Epigenetics. p. 1-11 11 p.

Research output: Contribution to journalArticle

DNA Methylation
Liver Neoplasms
Epigenomics
Disease Progression
Hepatocellular Carcinoma
94 Citations (Scopus)

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

Farshidfar, F., Zheng, S., Gingras, M. C., Newton, Y., Shih, J., Robertson, A. G., Hinoue, T., Hoadley, K. A., Gibb, E. A., Roszik, J., Covington, K. R., Wu, C. C., Shinbrot, E., Stransky, N., Hegde, A., Yang, J. D., Reznik, E., Sadeghi, S., Pedamallu, C. S., Ojesina, A. I. & 23 others, Hess, J. M., Auman, J. T., Rhie, S. K., Bowlby, R., Borad, M. J., Zhu, A. X., Stuart, J. M., Sander, C., Akbani, R., Cherniack, A. D., Deshpande, V., Mounajjed, T., Foo, W. C., Torbenson, M., Kleiner, D. E., Laird, P. W., Wheeler, D. A., McRee, A. J., Bathe, O. F., Andersen, J. B., Bardeesy, N., Roberts, L. R. & Patel, T. C., Mar 14 2017, In : Cell Reports. 18, 11, p. 2780-2794 15 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Genes
Mitochondrial DNA
Liver
Ducts
8 Citations (Scopus)

More advanced disease and worse survival in cryptogenic compared to viral hepatocellular carcinoma

Jun, T. W., Yeh, M. L., Yang, J. D., Chen, V. L., Nguyen, P., Giama, N. H., Huang, C. F., Hsing, A. W., Dai, C. Y., Huang, J. F., Chuang, W. L., Roberts, L. R., Yu, M. L. & Nguyen, M. H., 2017, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Survival
Hepatitis B virus
Hepacivirus
Fibrosis
18 Citations (Scopus)

MR elastography of hepatocellular carcinoma: Correlation of tumor stiffness with histopathology features—Preliminary findings

Thompson, S. M., Wang, J., Chandan, V. S., Glaser, K. J., Roberts, L. R., Ehman, R. L. & Venkatesh, S. K., Apr 1 2017, In : Magnetic Resonance Imaging. 37, p. 41-45 5 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Tumors
Hepatocellular Carcinoma
Stiffness
Neoplasms
4 Citations (Scopus)

Prevalence of hepatitis B antiviral drug resistance variants in North American patients with chronic hepatitis B not receiving antiviral treatment

the Hepatitis B Research Network (HBRN), Nov 1 2017, In : Journal of Viral Hepatitis. 24, 11, p. 1032-1042 11 p.

Research output: Contribution to journalArticle

Viral Drug Resistance
Chronic Hepatitis B
Hepatitis B
Hepatitis B virus
Antiviral Agents
13 Citations (Scopus)

Recent trends in the epidemiology of hepatocellular carcinoma in Olmsted County, Minnesota: A US population-based study

Yang, J. D., Mohammed, H. A., Harmsen, W. S., Enders, F. T., Gores, G. J. & Roberts, L. R., 2017, In : Journal of Clinical Gastroenterology. 51, 8, p. 742-748 7 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Epidemiology
Population
Fibrosis
Hepatitis B virus
9 Citations (Scopus)

Sleeping beauty insertional mutagenesis in mice identifies drivers of steatosis-associated hepatic tumors

Tschida, B. R., Temiz, N. A., Kuka, T. P., Lee, L. A., Riordan, J. D., Tierrablanca, C. A., Hullsiek, R., Wagner, S., Hudson, W. A., Linden, M. A., Amin, K., Beckmann, P. J., Heuer, R. A., Sarver, A. L., Yang, J. D., Roberts, L. R., Nadeau, J. H., Dupuy, A. J., Keng, V. W. & Largaespada, D. A., Dec 1 2017, In : Cancer Research. 77, 23, p. 6576-6588 13 p.

Research output: Contribution to journalArticle

Beauty
Insertional Mutagenesis
Hepatocellular Carcinoma
Liver
Neoplasms
8 Citations (Scopus)

Strategies to manage hepatitis C virus infection disease burden—Volume 4

Chen, D. S., Hamoudi, W., Mustapha, B., Layden, J., Nersesov, A., Reic, T., Garcia, V., Rios, C., Mateva, L., Njoya, O., Al-Busafi, S. A., Abdelmageed, M. K., Abdulla, M., Adda, D., Akin, O., Al Baqali, A., Al Dweik, N., Al Ejji, K., Al ghazzawi, I., Al Kaabi, S. & 109 others, Al Naamani, K., Al Qamish, J., Al Sadadi, M., Al Salman, J., AlBadri, M., Al-Romaihi, H. E., Ampofo, W., Antonov, K., Anyaike, C., Arome, F., Bane, A., Blach, S., Borodo, M. M., Brandon, S. M., Bright, B., Butt, M. T., Cardenas, I., Chan, H. L. Y., Chen, C. J., Chen, P. J., Chien, R. N., Chuang, W. L., Cuellar, D., Derbala, M., Elbardiny, A. A., Estes, C., Farag, E., Fung, J., Gamkrelidze, I., Genov, J., Ghandour, Z., Ghuloom, M., Gomez, B., Gunter, J., Habeeb, J., Hajelssedig, O., Himatt, S. M., Hrstic, I., Hu, C. C., Huang, C. F., Hui, Y. T., Jahis, R., Jelev, D., John, A. K., Kaliaskarova, K. S., Kamel, Y., Kao, J. H., Khamis, J., Khattabi, H., Khoudri, I., Konysbekova, A., Kotzev, I., Lai, M. S., Lao, W. C., Lee, M. H., Lesi, O., Li, M., Lo, A., Loo, C. K., Lukšić, B., Maaroufi, A., Malu, A. O., Mitova, R., Mohamed, R., Morović, M., Murphy, K., Nde, H., Ngige, E., Njouom, R., Nonković, D., Obekpa, S., Oguche, S., Okolo, E. E., Omede, O., Omuemu, C., Ondoa, P., Opare-Sem, O., Owusu-Ofori, S., Phillips, R. O., Prokopenko, Y. N., Razavi, H., Razavi-Shearer, D., Razavi-Shearer, K., Redae, B., Rinke de Wit, T., Robbins, S., Roberts, L. R., Sanad, S. J., Sharma, M., Simonova, M., Su, T. H., Sultan, K., Tan, S. S., Tchernev, K., Tsang, O. T. Y., Tsang, S., Tzeuton, C., Ugoeze, S., Uzochukwu, B., Vi, R., Vince, A., Wani, H. U., Wong, V. W. S., Workneh, A., Yacoub, R., Yesmembetov, K. I., Youbi, M., Yuen, M. F. & Schmelzer, J. D., Oct 1 2017, In : Journal of Viral Hepatitis. 24, p. 44-63 20 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Infection
Middle East
Latin America
5 Citations (Scopus)

The incidence rates and survival of gallbladder cancer in the USA

Jaruvongvanich, V., Yang, J. D., Peeraphatdit, T. & Roberts, L. R., Jul 4 2017, (Accepted/In press) In : European Journal of Cancer Prevention.

Research output: Contribution to journalArticle

Gallbladder Neoplasms
Survival Rate
Incidence
Confidence Intervals
Survival