Lewis Rowland Roberts, MB, ChB, PhD

  • 16512 Citations
  • 68 Scopus h-Index
1991 …2020
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Research Output 1991 2019

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Article
71 Citations (Scopus)

{A figure is presented}The Utility of Lens Culinaris Agglutinin-Reactive α-Fetoprotein in the Diagnosis of Hepatocellular Carcinoma: Evaluation in a United States Referral Population

Leerapun, A., Suravarapu, S. V., Bida, J. P., Clark, R. J., Sanders, E. L., Mettler, T. A., Stadheim, L. M., Aderca, I., Moser, C. D., Nagorney, D. M., La Russo, N. F., de Groen, P. C., Menon, K. V. N., Lazaridis, K. N., Gores, G. J., Charlton, M. R., Roberts, R. O., Therneau, T. M., Katzmann, J. A. & Roberts, L. R., Mar 2007, In : Clinical Gastroenterology and Hepatology. 5, 3, p. 394-402 9 p.

Research output: Contribution to journalArticle

Fetal Proteins
Hepatocellular Carcinoma
Referral and Consultation
Population
lentil lectin

67-Year-old man with hepatitis C infection and abdominal distention

Choong, N. W. W., Asfandiyar, S. & Roberts, L. R., Feb 1 2003, In : Mayo Clinic Proceedings. 78, 2, p. 217-220 4 p.

Research output: Contribution to journalArticle

Hepatitis C
Infection
530 Citations (Scopus)

AASLD guidelines for the treatment of hepatocellular carcinoma

Heimbach, J. K., Kulik, L. M., Finn, R. S., Sirlin, C. B., Abecassis, M. M., Roberts, L. R., Zhu, A. X., Murad, M. H. & Marrero, J. A., Jan 1 2018, In : Hepatology. 67, 1, p. 358-380 23 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Hepatocellular Carcinoma
Guidelines
61 Citations (Scopus)

Abrogation of MAPK and Akt signaling by AEE788 synergistically potentiates histone deacetylase inhibitor-induced apoptosis through reactive oxygen species generation

Yu, C., Friday, B. B., Lai, J. P., McCollum, A., Atadja, P., Roberts, L. R. & Adjei, A., Feb 15 2007, In : Clinical Cancer Research. 13, 4, p. 1140-1148 9 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Mitogen-Activated Protein Kinases
Reactive Oxygen Species
Apoptosis
trichostatin A
259 Citations (Scopus)

A comparison of routine cytology and fluorescence in situ hybridization for the detection of malignant bile duct strictures

Kipp, B. R., Stadheim, L. M., Halling, S. A., Pochron, N. L., Harmsen, S., Nagorney, D. M., Sebo, T. J., Therneau, T. M., Gores, G. J., De Groen, P. C., Baron, T. H., Levy, M. J., Halling, K. C. & Roberts, L. R., Sep 2004, In : American Journal of Gastroenterology. 99, 9, p. 1675-1681 7 p.

Research output: Contribution to journalArticle

Bile Ducts
Fluorescence In Situ Hybridization
Cell Biology
Pathologic Constriction
Neoplasms
68 Citations (Scopus)

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 690-705.e9

Research output: Contribution to journalArticle

Breast Neoplasms
Atlases
Long Noncoding RNA
Decision Trees
Genome
19 Citations (Scopus)

Activation of the transcription factor gli1 by wnt signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration

Nakamura, I., Fernandez-Barrena, M. G., Ortiz-Ruiz, M. C., Almada, L. L., Hu, C., Elsawa, S. F., Mills, L. D., Romecin, P. A., Gulaid, K. H., Moser, C. D., Han, J. J., Vrabel, A., Hanse, E. A., Akogyeram, N. A., Albrecht, J. H., Monga, S. P. S., Sanderson, S. O., Prieto, J., Roberts, L. R. & Fernandez-Zapico, M. E., Jul 19 2013, In : Journal of Biological Chemistry. 288, 29, p. 21389-21398 10 p.

Research output: Contribution to journalArticle

Tissue regeneration
Regeneration
Transcription Factors
Chemical activation
Sulfatases
22 Citations (Scopus)

Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma

Dhanasekaran, R., Nakamura, I., Hu, C., Chen, G., Oseini, A. M., Seven, E. S., Miamen, A. G., Moser, C. D., Zhou, W., van Kuppevelt, T. H., Van Deursen, J., Mounajjed, T., Fernandez-Zapico, M. E. & Roberts, L. R., Apr 1 2015, In : Hepatology. 61, 4, p. 1269-1283 15 p.

Research output: Contribution to journalArticle

Sulfatases
Transforming Growth Factors
Hepatocellular Carcinoma
Neoplasms
Transgenic Mice
26 Citations (Scopus)

Additive effect of apicidin and doxorubicin in sulfatase 1 expressing hepatocellular carcinoma in vitro and in vivo

Lai, J. P., Sandhu, D. S., Moser, C. D., Cazanave, S. C., Oseini, A. M., Shire, A. M., Shridhar, V., Sanderson, S. O. & Roberts, L. R., Jun 2009, In : Journal of Hepatology. 50, 6, p. 1112-1121 10 p.

Research output: Contribution to journalArticle

Sulfatases
Doxorubicin
Hepatocellular Carcinoma
Caspases
Histone Deacetylase Inhibitors
215 Citations (Scopus)

Advanced Cytologic Techniques for the Detection of Malignant Pancreatobiliary Strictures

Moreno Luna, L. E., Kipp, B., Halling, K. C., Sebo, T. J., Kremers, W. K., Roberts, L. R., Barr Fritcher, E. G., Levy, M. J. & Gores, G. J., Oct 2006, In : Gastroenterology. 131, 4, p. 1064-1072 9 p.

Research output: Contribution to journalArticle

Cell Biology
Fluorescence In Situ Hybridization
Pathologic Constriction
Cystic Duct
Sclerosing Cholangitis

Age, race and viral genotype are associated with the prevalence of hepatitis B e antigen in children and adults with chronic hepatitis B

the Hepatitis B Research Network (HBRN), Jul 1 2019, In : Journal of viral hepatitis. 26, 7, p. 856-865 10 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Chronic Hepatitis B
Genotype
Hepatitis B virus
Virus Diseases
19 Citations (Scopus)

A major estrogen-regulated protein secreted from the liver of xenopus Laevis is a member of the serpin superfamily: Nucleotide sequence of cDNA and hormonal Induction of mRNA

Holland, L. J., Suksang, C., Wall, A. A., Roberts, L. R., Moser, D. R. & Bhattacharya, A., Apr 5 1992, In : Journal of Biological Chemistry. 267, 10, p. 7053-7059 7 p.

Research output: Contribution to journalArticle

Serpins
Xenopus laevis
Liver
Nucleotides
Complementary DNA
1 Citation (Scopus)

A model predicting short-term mortality in patients with advanced liver cirrhosis and concomitant infection

Li, Y., Chaiteerakij, R., Kwon, J. H., Jang, J. W., Lee, H. L., Cha, S., Ding, X. W., Thongprayoon, C., Ha, F. S., Nie, C. Y., Zhang, Q., Yang, Z., Giama, N. H., Roberts, L. R. & Han, T., Oct 1 2018, In : Medicine. 97, 41, p. e12758

Research output: Contribution to journalArticle

End Stage Liver Disease
ROC Curve
Liver Cirrhosis
Decision Trees
Mortality
1 Citation (Scopus)

A Moveable Feast

Camilleri, M., Sandborn, W. J., Kolars, J. C., Murray, J. A., Poterucha, J. J., Roberts, L. R., Sinicrope, F. A. & Wang, K. K. N., Jun 2007, In : Clinical Gastroenterology and Hepatology. 5, 6, p. 646-647 2 p.

Research output: Contribution to journalArticle

Gastroenterology
113 Citations (Scopus)

A Multivariable Model Using Advanced Cytologic Methods for the Evaluation of Indeterminate Pancreatobiliary Strictures

Barr Fritcher, E. G., Kipp, B. R., Halling, K. C., Oberg, T. N., Bryant, S. C., Tarrell, R. F., Gores, G. J., Levy, M. J., Clayton, A. C., Sebo, T. J. & Roberts, L. R., Jun 2009, In : Gastroenterology. 136, 7, p. 2180-2186 7 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Pathologic Constriction
Cell Biology
Sclerosing Cholangitis
Trisomy
38 Citations (Scopus)

An assessment of chromosomal alterations detected by fluorescence in situ hybridization and p16 expression in sporadic and primary sclerosing cholangitis-associated cholangiocarcinomas

DeHaan, R. D., Kipp, B. R., Smyrk, T. C., Abraham, S. C., Roberts, L. R. & Halling, K. C., Mar 2007, In : Human Pathology. 38, 3, p. 491-499 9 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiocarcinoma
Fluorescence In Situ Hybridization
Chromosome Aberrations
Neoplasms

A necrotic liver mass

Sweetser, S., Roberts, L. R. & Medeiros, F., Sep 2010, In : Gastroenterology. 139, 3

Research output: Contribution to journalArticle

Fallopian Tube Neoplasms
Papillary Adenocarcinoma
X Ray Computed Tomography
Inferior Vena Cava
Liver Neoplasms

An Enlarging Metastatic Calcified Liver Lesion of an Occult Melanoma

Mouchli, M. A., Kerr, S. E. & Roberts, L. R., Jun 18 2018, (Accepted/In press) In : Case Reports in Oncology. p. 388-391 4 p.

Research output: Contribution to journalArticle

Melanoma
Liver
Hemangioma
Liver Neoplasms
Blood Vessels
1 Citation (Scopus)

A new, effective and high-yield approach for identifying liver tumor suppressors

Olgun, E. & Roberts, L. R., Feb 26 2009, In : Genome Medicine. 1, 2, gm26.

Research output: Contribution to journalArticle

Liver
Carcinogenesis
Neoplasms
Comparative Genomic Hybridization
Oncogenes
41 Citations (Scopus)

A new clinically based staging system for perihilar cholangiocarcinoma

Chaiteerakij, R., Harmsen, W. S., Marrero, C. R., Aboelsoud, M. M., Ndzengue, A., Kaiya, J., Therneau, T. M., Sanchez, W., Gores, G. J. & Roberts, L. R., Dec 11 2014, In : American Journal of Gastroenterology. 109, 12, p. 1881-1890 10 p.

Research output: Contribution to journalArticle

Klatskin Tumor
Survival
Clinical Trials
Neoplasms
Neoplasm Metastasis
9 Citations (Scopus)

A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice

Koh, M. Y., Gagea, M., Sargis, T., Lemos, R., Grandjean, G., Charbono, A., Bekiaris, V., Sedy, J., Kiriakova, G., Liu, X., Roberts, L. R., Ware, C. & Powis, G., May 1 2016, In : Hepatology. 63, 5, p. 1576-1591 16 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Hypoxia-Inducible Factor 1
Hepatocellular Carcinoma
T-Lymphocytes
Liver
139 Citations (Scopus)

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 400-416.e11

Research output: Contribution to journalArticle

Atlases
Genes
Genome
Survival
Neoplasms
35 Citations (Scopus)

An Optimized Set of Fluorescence in Situ Hybridization Probes for Detection of Pancreatobiliary Tract Cancer in Cytology Brush Samples

Barr Fritcher, E. G., Voss, J. S., Brankley, S. M., Campion, M. B., Jenkins, S. M., Keeney, M. E., Henry, M. R., Kerr, S. M., Chaiteerakij, R., Pestova, E. V., Clayton, A. C., Zhang, J., Roberts, L. R., Gores, G. J., Halling, K. C. & Kipp, B. R., Dec 1 2015, In : Gastroenterology. 149, 7, p. 1813-1824e1

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Cell Biology
Neoplasms
Sclerosing Cholangitis
Clinical Pathology
671 Citations (Scopus)

A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells

Lee, J. S., Heo, J., Libbrecht, L., Chu, I. S., Kaposi-Novak, P., Calvisi, D. F., Mikaelyan, A., Roberts, L. R., Demetris, A. J., Sun, Z., Nevens, F., Roskams, T. & Thorgeirsson, S. S., Apr 2006, In : Nature Medicine. 12, 4, p. 410-416 7 p.

Research output: Contribution to journalArticle

Gene expression
Hepatocytes
Hepatocellular Carcinoma
Stem Cells
Tumors
9 Citations (Scopus)

Anti-invasion and anti-migration effects of miR-199a-3p in hepatocellular carcinoma are due in part to targeting CD151

Kim, J. H., Badawi, M., Park, J. K., Jiang, J., Mo, X., Roberts, L. R. & Schmittgen, T. D., Nov 1 2016, In : International Journal of Oncology. 49, 5, p. 2037-2045 9 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Proteins
Messenger RNA
Luciferases
Small Interfering RNA
30 Citations (Scopus)

Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein

Wang, Y., Ding, X., Wang, S., Moser, C. D., Shaleh, H. M., Mohamed, E. A., Chaiteerakij, R., Allotey, L. K., Chen, G., Miyabe, K., McNulty, M. S., Ndzengue, A., Barr Fritcher, E. G., Knudson, R. A., Greipp, P. T., Clark, K. J., Torbenson, M., Kipp, B. R., Zhou, J., Barrett, M. & 4 others, Gustafson, M., Alberts, S. R., Borad, M. J. & Roberts, L. R., Sep 28 2016, In : Cancer Letters. 380, 1, p. 163-173 11 p.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 2
Cholangiocarcinoma
Heterografts
Proteins
Neoplasms
17 Citations (Scopus)

Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells

Ding, X., Chaiteerakij, R., Moser, C. D., Shaleh, H., Boakye, J., Chen, G., Ndzengue, A., Li, Y., Zhou, Y., Huang, S., Sinicrope, F. A., Zou, X., Thomas, M. B., Smith, C. D. & Roberts, L. R., Apr 12 2016, In : Oncotarget. 7, 15, p. 20080-20092 13 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Autophagy
Phosphorylation
Cell Proliferation
Apoptosis
3 Citations (Scopus)

Anti-viral therapy is associated with improved survival but is underutilised in patients with hepatitis B virus-related hepatocellular carcinoma: real-world east and west experience

Chen, V. L., Yeh, M. L., Le, A. K., Jun, M., Saeed, W. K., Yang, J. D., Huang, C. F., Lee, H. Y., Tsai, P. C., Lee, M. H., Giama, N., Kim, N. G., Nguyen, P. P., Dang, H., Ali, H. A., Zhang, N., Huang, J. F., Dai, C. Y., Chuang, W. L., Roberts, L. R. & 4 others, Jun, D. W., Lim, Y. S., Yu, M. L. & Nguyen, M. H., Jul 1 2018, In : Alimentary Pharmacology and Therapeutics. 48, 1, p. 44-54 11 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Survival
Fibrosis
Therapeutics
36 Citations (Scopus)

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 386-399.e12

Research output: Contribution to journalArticle

Genes
Tumors
Neoplasms
Computational methods
Chromatin
13 Citations (Scopus)

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

The Cancer Genome Atlas Research Network, Oct 24 2018, In : Cell Systems. 7, 4, p. 422-437.e7

Research output: Contribution to journalArticle

Transforming Growth Factors
Neoplasms
Sequence Deletion
Genes
Gastrointestinal Neoplasms
25 Citations (Scopus)

A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation

Chien, J., Narita, K., Rattan, R., Giri, S., Shridhar, R., Staub, J., Beleford, D., Lai, J., Roberts, L. R., Molina, J. R., Kaufmann, S. H., Prendergast, G. C. & Shridhar, V., Dec 11 2008, In : Oncogene. 27, 58, p. 7223-7234 12 p.

Research output: Contribution to journalArticle

Cyclin D1
Tumor Suppressor Genes
Down-Regulation
Ornithine Decarboxylase
Epithelial Cells
13 Citations (Scopus)

AS30D model of hepatocellular carcinoma: Tumorigenicity and preliminary characterization by imaging, histopathology, and immunohistochemistry

Thompson, S. M., Callstrom, M. R., Knudsen, B., Anderson, J. L., Butters, K. A., Grande, J. P., Roberts, L. R. & Woodrum, D. A., Feb 2013, In : CardioVascular and Interventional Radiology. 36, 1, p. 198-203 6 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Immunohistochemistry
Liver
Cell Line
Neoplasms
32 Citations (Scopus)

Ascites and hepatorenal syndrome: Pathophysiology and management

Roberts, L. R. & Kamath, P. S., 1996, In : Mayo Clinic Proceedings. 71, 9, p. 874-881 8 p.

Research output: Contribution to journalArticle

Hepatorenal Syndrome
Ascites
Diuretics
Liver Transplantation
Fibrosis
gemcitabine
Cholangiocarcinoma
Cisplatin
Epidemiology
Survival
32 Citations (Scopus)

Aspirin use and the risk of cholangiocarcinoma

Choi, J., Ghoz, H. M., Peeraphatdit, T., Baichoo, E., Addissie, B. D., Harmsen, W. S., Therneau, T. M., Olson, J. E., Chaiteerakij, R. & Roberts, L. R., 2016, In : Hepatology. 64, 3, p. 785-796 12 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Aspirin
Confidence Intervals
Odds Ratio
Sclerosing Cholangitis
2 Citations (Scopus)
Hepatitis B e Antigens
Alanine Transaminase
DNA
Infection
Serum
1 Citation (Scopus)

Association between treatment facility volume, therapy types and overall survival in patients with intrahepatic cholangiocarcinoma

Kommalapati, A., Tella, S. H., Goyal, G., Borad, M. J., Alberts, S. R., Roberts, L. R., Hubbard, J. M., Durgin, L., Cleary, S. & Mahipal, A., Jan 1 2018, (Accepted/In press) In : HPB.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Survival
Liver
Therapeutics
Insurance
4 Citations (Scopus)

Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma

Chaiteerakij, R., Juran, B. D., Aboelsoud, M. M., Harmsen, W. S., Moser, C. D., Giama, N. H., Allotey, L. K., Mettler, T. A., Baichoo, E., Zhang, X., Therneau, T. M., Lazaridis, K. N. & Roberts, L. R., Oct 1 2015, In : Cancer Medicine. 4, 10, p. 1599-1602 4 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Neoplasm Genes
Inflammation
Survival
Single Nucleotide Polymorphism
433 Citations (Scopus)

Association of microRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival

Jiang, J., Gusev, Y., Aderca, I., Mettler, T. A., Nagorney, D. M., Brackett, D. J., Roberts, L. R. & Schmittgen, T. D., Jan 15 2008, In : Clinical Cancer Research. 14, 2, p. 419-427 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Hepatitis
Hepatocellular Carcinoma
Fibrosis
Survival

Barriers in Hepatitis C Treatment in Somali Patients in the Direct Acting Antiviral Therapy Era

Elwir, S., Anugwom, C., Connor, E. K., Giama, N. H., Ndzengue, A., Menk, J., Mohamed, E. A., Roberts, L. R. & Hassan, M., Jan 1 2018, (Accepted/In press) In : Journal of the National Medical Association.

Research output: Contribution to journalArticle

Hepatitis C
Antiviral Agents
Hepacivirus
Therapeutics
Genotype
41 Citations (Scopus)

Biliary tract cancers in olmsted county, Minnesota, 1976-2008

Yang, J. D., Kim, B., Sanderson, S. O., St. Sauver, J., Yawn, B. P., Larson, J. J., Therneau, T. M., Roberts, L. R., Gores, G. J. & Kim, W. R., Aug 2012, In : American Journal of Gastroenterology. 107, 8, p. 1256-1262 7 p.

Research output: Contribution to journalArticle

Biliary Tract Neoplasms
Survival
Incidence
Gallbladder Neoplasms
Cholangiocarcinoma
4 Citations (Scopus)

Biomarkers for hepatocellular carcinoma

Roberts, L. R., Apr 1 2016, In : Gastroenterology and Hepatology. 12, 4, p. 252-255 4 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Biomarkers
1 Citation (Scopus)

Biomarkers for hepatocellular carcinoma

Roberts, L. R., 2016, In : Clinical Advances in Hematology and Oncology. 14, 4, p. 223-226 4 p.

Research output: Contribution to journalArticle

X Ray Computed Tomography
alpha-Fetoproteins
Liver Neoplasms
Tumor Biomarkers
Hepatocellular Carcinoma
16 Citations (Scopus)

Biphenotypic hepatic tumors: imaging findings and review of literature

Wells, M., Venkatesh, S. K., Chandan, V. S., Fidler, J. L., Fletcher, J. G., Johnson, G. B., Hough, D. M. & Roberts, L. R., May 8 2015, (Accepted/In press) In : Abdominal Imaging.

Research output: Contribution to journalArticle

Tumor Biomarkers
Liver
Neoplasms
Cholangiocarcinoma
Hepatocellular Carcinoma
32 Citations (Scopus)

Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling

Nakamura, I., Zakharia, K., Banini, B. A., Mikhail, D. S., Kim, T. H., Yang, J. D., Moser, C. D., Shaleh, H. M., Thornburgh, S. R., Walters, I. & Roberts, L. R., Apr 7 2014, In : PLoS One. 9, 4, e92273.

Research output: Contribution to journalArticle

platelet-derived growth factor
liver cirrhosis
Platelet-Derived Growth Factor
Liver
Vascular Endothelial Growth Factor A
1 Citation (Scopus)

Casting a wider net: Improving access to medical literature in developing countries

Roberts, L. R., Missen, C. & Grimes, G. C., 2007, In : Mayo Clinic Proceedings. 82, 7, p. 846-848 3 p.

Research output: Contribution to journalArticle

Digital Libraries
Developing Countries
Delivery of Health Care
Quality of Health Care
Evidence-Based Medicine
151 Citations (Scopus)

Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes

Roberts, L. R., Kurosawa, H., Bronk, S. F., Fesmier, P. J., Agellon, L. B., Leung W.-, Y., Mao, F. & Gores, G. J., 1997, In : Gastroenterology. 113, 5, p. 1714-1726 13 p.

Research output: Contribution to journalArticle

Cathepsin B
Bile Acids and Salts
Hepatocytes
Apoptosis
Glycochenodeoxycholic Acid
91 Citations (Scopus)

Cathepsins as effector proteases in hepatocyte apoptosis

Roberts, L. R., Adjei, P. N. & Gores, G. J., 1999, In : Cell Biochemistry and Biophysics. 30, 1, p. 71-88 18 p.

Research output: Contribution to journalArticle

Pepstatins
Antisense DNA
Topoisomerase Inhibitors
Cathepsins
Camptothecin
2 Citations (Scopus)

Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice

Aziz, K., Limzerwala, J. F., Sturmlechner, I., Hurley, E., Zhang, C., Jeganathan, K. B., Nelson, G., Bronk, S., Fierro Velasco, R. O., van Deursen, E. J., O'Brien, D. R., Kocher, J-P., Youssef, S. A., van Ree, J. H., de Bruin, A., van den Bos, H., Spierings, D. C. J., Foijer, F., van de Sluis, B., Roberts, L. R. & 3 others, Gores, G. J., Li, H. & Van Deursen, J., Jul 1 2019, In : Gastroenterology. 157, 1, p. 210-226.e12

Research output: Contribution to journalArticle

Chromosomal Instability
Cyclins
Liver
Neoplasms
Chromosomes
3 Citations (Scopus)

cDNA and amino-acid sequences and organization of the gene encoding the Bβ subunit of fibrinogen from Xenopus laevis

Roberts, L. R., Nichols, L. A. & Holland, L., 1995, In : Gene. 160, 2, p. 223-228 6 p.

Research output: Contribution to journalArticle

Xenopus laevis
Fibrinogen
Amino Acid Sequence
Complementary DNA
Genes