Leif Bergsagel, MD

Accepting PhD Students

  • 23242 Citations
  • 82 Scopus h-Index
1984 …2020
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Leif Bergsagel is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Multiple Myeloma Medicine & Life Sciences
Plasma Cells Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Dexamethasone Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Tumors Chemical Compounds
Cell Line Medicine & Life Sciences
Survival Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1997 2020

Monoclonal Gammopathy of Undetermined Significance
Plasma Cells
Multiple Myeloma
Mutation
Bone Neoplasms
Multiple Myeloma
Oncolytic Virotherapy
Clonal Evolution
Vesicular Stomatitis
Research
Multiple Myeloma
Therapeutics
Cell Line
Clustered Regularly Interspaced Short Palindromic Repeats
Polyploidy
Multiple Myeloma
Disease Progression
Polyploidy
Mutation
Drug Resistance

Research Output 1984 2019

Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model

Guillerey, C., Nakamura, K., Pichler, A. C., Barkauskas, D., Krumeich, S., Stannard, K., Miles, K., Harjunpää, H., Yu, Y., Casey, M., Doban, A. I., Lazar, M., Hartel, G., Smith, D., Vuckovic, S., Teng, M. W. L., Bergsagel, P. L., Chesi, M., Hill, G. R., Martinet, L. & 1 others, Smyth, M. J., Jul 25 2019, In : JCI Insight. 4, 14, :e125932.

Research output: Contribution to journalArticle

Open Access
Multiple Myeloma
Immunotherapy
Drug Therapy
T-Lymphocytes
Therapeutics
1 Citation (Scopus)

Dynamic CD138 surface expression regulates switch between myeloma growth and dissemination

Akhmetzyanova, I., McCarron, M. J., Parekh, S., Chesi, M., Bergsagel, P. L. & Fooksman, D. R., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Growth
Syndecan-1
Bone and Bones
Plasma Cells
Cell Movement
3 Citations (Scopus)

Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4

Zhu, Y. X., Shi, C. X., Bruins, L. A., Wang, X., Riggs, D. L., Porter, B., Ahmann, J. M., de Campos, C. B., Braggio, E. D., Bergsagel, P. L. & Stewart, A. K., Feb 1 2019, In : Blood cancer journal. 9, 2, 19.

Research output: Contribution to journalArticle

Open Access
Multiple Myeloma
Cell Line
Down-Regulation
lenalidomide
Sequence Deletion

MYC dysregulation in the progression of multiple myeloma

MMRF CoMMpass Network, Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalLetter

Multiple Myeloma

Oncolytic immunotherapy and bortezomib synergy improves survival of refractory multiple myeloma in a preclinical model

Thirukkumaran, C. M., Shi, Z. Q., Nuovo, G. J., Luider, J., Kopciuk, K. A., Dong, Y., Mostafa, A. A., Thakur, S., Gratton, K., Yang, A., Chin, A. C., Coffey, M. C., Jimenez-Zepeda, V. H., Stewart, D., Chesi, M., Bergsagel, P. L. & Morris, D., Mar 12 2019, In : Blood advances. 3, 5, p. 797-812 16 p.

Research output: Contribution to journalArticle

Open Access
Multiple Myeloma
Immunotherapy
Survival
Neoplasms
Therapeutics