• 17984 Citations
  • 47 Scopus h-Index
1979 …2021

Research output per year

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Research Output

  • 17984 Citations
  • 47 Scopus h-Index
  • 194 Article
  • 13 Comment/debate
  • 6 Review article
  • 1 Chapter
Article

[10] Specific amplification of complementary DNA from targeted members of multigene families

Cai, Z., Pullen, J. K., Horton, R. M. & Pease, L. R., Jan 1 1992, In : Methods in Enzymology. 216, p. 100-108 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

[17] Gene Splicing by Overlap Extension

Horton, R. M., Ho, S. N., Pullen, J. K., Hunt, H. D., Cai, Z. & Pease, L. R., Jan 1 1993, In : Methods in Enzymology. 217, C, p. 270-279 10 p.

Research output: Contribution to journalArticle

405 Scopus citations

A(β) polymorphic residues responsible for class II molecule recognition by alloreactive T cells

Buerstedde, J. M., Nilson, A. E., Chase, C. G., Bell, M. P., Beck, B. N., Pease, L. R. & McKean, D. J., Jan 1 1989, In : Journal of Experimental Medicine. 169, 5, p. 1645-1654 10 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

A 40-cM Region on Chromosome 14 Plays a Critical Role in the Development of Virus Persistence, Demyelination, Brain Pathology and Neurologic Deficits in a Murine Viral Model of Multiple Sclerosis

Nakane, S., Zoecklein, L. J., Gamez, J. D., Papke, L. M., Pavelko, K. D., Bureau, J. F., Brahic, M., Pease, L. R. & Rodriguez, M., Oct 1 2003, In : Brain Pathology. 13, 4, p. 519-533 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Abrogation of resistance to Theiler's virus-induced demyelination in C57BL mice by total body irradiation

Rodiriguez, M., Patrick, A. K. & Pease, L. R., Mar 1990, In : Journal of neuroimmunology. 26, 3, p. 189-199 11 p.

Research output: Contribution to journalArticle

40 Scopus citations

Acidic polyamino acids inhibit human eosinophil granule major basic protein toxicity: Evidence of a functional role for ProMBP

Barker, R. L., Gundel, R. H., Gleich, G. J., Checkel, J. L., Loegering, D. A., Pease, L. R. & Hamann, K. J., Sep 1991, In : Journal of Clinical Investigation. 88, 3, p. 798-805 8 p.

Research output: Contribution to journalArticle

Open Access
71 Scopus citations

Acidic precursor revealed in human eosinophil granule major basic protein cDNA

Barker, R. L., Gleich, G. J. & Pease, L. R., Oct 1 1988, In : Journal of Experimental Medicine. 168, 4, p. 1493-1498 6 p.

Research output: Contribution to journalArticle

Open Access
95 Scopus citations

A class I transgene reveals regulatory events on chromosome 1 marking peripheral T cell differentiation and memory

Sloma, C. R., Hansen, M. J., MacDougall, A. A., Van Keulen, V. P., Jenkins, R. B. & Pease, L. R., Jun 15 2005, In : Journal of Immunology. 174, 12, p. 7564-7572 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A common mutation in the hominoid class I A-locus IFN-responsive element results in the loss of enhancer activity

Vallejo, A. N., Allen, K. S. & Pease, L. R., May 1 1995, In : International Immunology. 7, 5, p. 853-859 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
13 Scopus citations

A factor found in the igg fraction of serum of patients with paraneoplastic bilateral diffuse uveal melanocytic proliferation causes proliferation of cultured human melanocytes

Miles, S. L., Niles, R. M., Pittock, S., Vile, R., Davies, J., Winters, J. L., Abu-Yaghi, N. E., Grothey, A., Siddiqui, M., Kaur, J., Hartmann, L., Kalli, K. R., Pease, L., Kravitz, D., Markovic, S. & Pulido, J. S., Oct 1 2012, In : Retina. 32, 9, p. 1959-1966 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Age-Dependent Paralytic Viral Infection in C58 Mice: Possible Implications in Human Neurologic Disease

Murphy, W. H., Nawrocki, J. F. & Pease, L. R., Jan 1 1983, In : Progress in Brain Research. 59, C, p. 291-303 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

A human antibody that promotes remyelination enters the CNS and decreases lesion load as detected by T2-weighted spinal cord MRI in a virus-induced murine model of MS

Pirko, I., Ciric, B., Gamez, J., Bieber, A. J., Warrington, A. E., Johnson, A. J., Hanson, D. P., Pease, L. R., Macura, S. I. & Rodriguez, M., Oct 1 2004, In : FASEB Journal. 18, 13, p. 1577-1579 3 p.

Research output: Contribution to journalArticle

79 Scopus citations

A human IgM signals axon outgrowth: Coupling lipid raft to microtubules

Xu, X., Warrington, A. E., Wright, B. R., Bieber, A. J., Van Keulen, V., Pease, L. R. & Rodriguez, M., Oct 1 2011, In : Journal of neurochemistry. 119, 1, p. 100-112 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Allelic variation in the Tyk2 and EGF genes as potential genetic determinants of CNS repair

Bieber, A. J., Suwansrinon, K., Kerkvliet, J., Zhang, W., Pease, L. R. & Rodriguez, M., Feb 15 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 2, p. 792-797 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Alloreactive 2C T cells recognize a self peptide in the context of the mutant Kbm3 molecule

Tallquist, M. D. & Pease, L. R., Jan 1 1995, In : Journal of Immunology. 155, 5, p. 2419-2426 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Alloreactive cytotoxic T lymphocytes recognize epitopes determined by both the α helices and β sheets of the class I peptide binding site

Hunt, H. D., Munitz, T. I. & Pease, L. R., Mar 1 1992, In : Journal of Experimental Medicine. 175, 3, p. 821-829 9 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Alternative pre-mRNA splicing of Kj eliminates a sequence that is unique to H-2K transcripts

Pogulis, R. J. & Pease, L. R., Feb 1994, In : Molecular Immunology. 31, 3, p. 241-243 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Amino acid changes in the peptide binding site have structural consequences at the surface of class I glycoproteins

Pease, L. R., Horton, R. M., Pullen, J. K., Hunt, H. D., Yun, T. J., Rohren, E. M., Prescott, J. L., Jobe, S. M. & Allen, K. S., Jan 1 1993, In : Journal of Immunology. 150, 8 I, p. 3375-3381 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens

Asakura, K., Pogulis, R. J., Pease, L. R. & Rodriguez, M., Mar 1996, In : Journal of neuroimmunology. 65, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Anatomical and cellular requirements for the activation and migration of virus-specific CD8+ T cells to the brain during Theiler's virus infection

Mendez-Fernandez, Y. V., Hansen, M. J., Rodriguez, M. & Pease, L. R., Mar 1 2005, In : Journal of virology. 79, 5, p. 3063-3070 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis

Xu, X., Denic, A., Jordan, L. R., Wittenberg, N. J., Warrington, A. E., Wootla, B., Papke, L. M., Zoecklein, L. J., Yoo, D., Shaver, J., Oh, S. H., Pease, L. R. & Rodriguez, M., Aug 1 2015, In : DMM Disease Models and Mechanisms. 8, 8, p. 831-842 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

An effective vaccine strategy protective against antigenically distinct tumor variants

Pavelko, K. D., Heckman, K. L., Hansen, M. J. & Pease, L. R., Apr 1 2008, In : Cancer research. 68, 7, p. 2471-2478 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

An intragenic recombinant class I gene: H-2Ddx

Cai, Z. & Pease, L. R., Oct 1 1991, In : Immunogenetics. 34, 4, p. 273-276 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody

Howe, C. L., Bieber, A. J., Warrington, A. E., Pease, L. R. & Rodriguez, M., Feb 2004, In : Neurobiology of Disease. 15, 1, p. 120-131 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

Antibody-mediated remyelination operates through mechanism independent of immunomodulation

Ciric, B., Van Keulen, V., Paz Soldan, M., Rodriguez, M. & Pease, L. R., Jan 2004, In : Journal of neuroimmunology. 146, 1-2, p. 153-161 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Antigen-specific CD8+ T cells mediate a peptide-induced fatal syndrome

Johnson, A. J., Mendez-Fernandez, Y., Moyer, A. M., Sloma, C. R., Pirko, I., Block, M. S., Rodriguez, M. & Pease, L. R., Jun 1 2005, In : Journal of Immunology. 174, 11, p. 6854-6862 9 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

A recombinant human IgM promotes myelin repair after a single, very low dose

Warrington, A. E., Bieber, A. J., Ciric, B., Pease, L. R., Van Keulen, V. & Rodriguez, M., Apr 1 2007, In : Journal of Neuroscience Research. 85, 5, p. 967-976 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

A region of conformational variability outside the peptide-binding site of a class I MHC molecule

Kuhns, S. T. & Pease, L. R., Dec 15 1998, In : Journal of Immunology. 161, 12, p. 6745-6750 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

A retroviral vector that directs simultaneous expression of α and β T cell receptor genes

Pogulis, R. J. & Pease, L. R., Oct 10 1998, In : Human gene therapy. 9, 15, p. 2299-2304 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

A single dose of neuron-binding human monoclonal antibody improves spontaneous activity in a murine model of demyelination

Denic, A., Macura, S. I., Warrington, A. E., Pirko, I., Grossardt, B. R., Pease, L. R. & Rodriguez, M., Oct 12 2011, In : PloS one. 6, 10, e26001.

Research output: Contribution to journalArticle

18 Scopus citations

A single T cell receptor recognizes structurally distinct MHC/peptide complexes with high specificity

Dtallquist, M., Theodore, J. Y. & Pease, L. R., Sep 1 1996, In : Journal of Experimental Medicine. 184, 3, p. 1017-1026 10 p.

Research output: Contribution to journalArticle

121 Scopus citations

Asthma-related environmental fungus, Alternaria, activates dendritic cells and produces potent TH2 adjuvant activity

Kobayashi, T., Iijima, K., Radhakrishnan, S., Mehta, V., Vassallo, R., Lawrence, C. B., Cyong, J. C., Pease, L. R., Oguchi, K. & Kita, H., Feb 15 2009, In : Journal of Immunology. 182, 4, p. 2502-2510 9 p.

Research output: Contribution to journalArticle

74 Scopus citations

A Theiler's virus alternatively initiated protein inhibits the generation of H-2K-restricted virus-specific cytotoxicity

Lin, X., Roos, R. P., Pease, L. R., Wettstein, P. & Rodriguez, M., Jan 1 1999, In : Journal of Immunology. 162, 1, p. 17-24 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

A versatile simple capture assay for assessing the structural integrity of MHC multimer reagents

Reed, B. K., Chopp, L. B., Malo, C. S., Renner, D. N., Van Keulen, V. S., Girtman, M. A., Nevala, W. N., Pavelko, K. D., Gil, D., Schrum, A. G., Johnson, A. J. & Pease, L. R., Sep 21 2015, In : PLoS One. 10, 9, e0137984.

Research output: Contribution to journalArticle

2 Scopus citations

B7-DC/PD-L2 cross-linking induces NF-κB-dependent protection of dendritic cells from cell death

Radhakrishnan, S., Nguyen, L. T., Ciric, B., Van Keulen, V. P. & Pease, L. R., Feb 1 2007, In : Journal of Immunology. 178, 3, p. 1426-1432 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
32 Scopus citations

Biochemical studies of H-2K antigens from a group of related mutants. I. Identification of a shared mutation in B6-H-2bm5 and B6-H-2bm16

Yamaga, K. M., Pfaffenbach, G. M., Pease, L. R., Mc Governs, D., Nisizawa, T., Melvold, R. W., Kohn, H. I. & Nathenson, S. G., Jan 1983, In : Immunogenetics. 17, 1, p. 19-29 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Biochemical studies of H-2K antigens from a group of related mutants. II. Identification of a shared mutation in B6-H-2bm6, B6.C-H-2bm7, and B6. C-H-2bm9

Yamaga, K. M., Pfaffenbach, G. M., Pease, L. R., McGovern, D., Nisizawa, T., Melvold, R. W., Kohn, H. I. & Nathenson, S. G., Jan 1983, In : Immunogenetics. 17, 1, p. 31-41 11 p.

Research output: Contribution to journalArticle

Biochemical studies on the H-2K mutant B6.C-H-2bm10

Pease, L. R., Ewenstein, B. M., McGovern, D., Melvold, R. W., Nisizawa, T. & Nathenso, S. G., Jan 1983, In : Immunogenetics. 17, 1, p. 7-17 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Blockade of allergic airway inflammation following systemic treatment with a B7-dendritic cell (PD-L2) cross-linking human antibody

Radhakrishnan, S., Iijima, K., Kobayashi, T., Rodriguez, M., Kita, H. & Pease, L. R., Jul 15 2004, In : Journal of Immunology. 173, 2, p. 1360-1365 6 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Blockade of LIGHT/LTβ and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease

Tamada, K., Tamura, H., Flies, D., Fu, Y. X., Celis, E., Pease, L. R., Blazar, B. R. & Chen, L., Jan 1 2002, In : Journal of Clinical Investigation. 109, 4, p. 549-557 9 p.

Research output: Contribution to journalArticle

76 Scopus citations

Blockade of LIGHT/LTβ and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease

Tamada, K., Tamura, H., Flies, D., Fu, Y. X., Celis, E., Pease, L. R., Blazar, B. R. & Chen, L., 2002, In : Journal of Clinical Investigation. 109, 4, p. 549-557 9 p.

Research output: Contribution to journalArticle

Breaking tolerance with engineered class I antigen-presenting molecules

Parks, C. A., Henning, K. R., Pavelko, K. D., Hansen, M. J., Van Keulen, V. P., Reed, B. K., Stone, J. D., Schrum, A. G., Gil, D., Kranz, D. M., Bordner, A. J., Barry, M. A. & Pease, L. R., Feb 19 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 8, p. 3136-3145 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Calcium-modulating cyclophilin ligand is essential for the survival of activated t cells and for adaptive immunity

Chan, S. L., Lindquist, L. D., Hansen, M. J., Girtman, M. A., Pease, L. R. & Bram, R. J., Dec 15 2015, In : Journal of Immunology. 195, 12, p. 5648-5656 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

CD8 expression alters the fine specificity of an alloreactive MHC class l-specific T hybridoma

Blok, R., Margulies, D. H., Pease, L., Ribaudo, R. K., Schneck, J. & Mccluskey, J., Apr 1 1992, In : International Immunology. 4, 4, p. 455-466 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Cellular sources and targets of IFN-γ-mediated protection against viral demyelination and neurological deficits

Murray, P. D., McGavern, D. B., Pease, L. R. & Rodriguez, M., Apr 9 2002, In : European Journal of Immunology. 32, 3, p. 606-615 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Characterization of the spontaneous mutant H-2Kbm29 indicates that gene conversion in H-2 occurs at a higher frequency than detected by skin grafting

Horton, R. M., Loveland, B. E., Parwani, A., Pease, L. R. & Lindahl, K. F., Jan 1 1991, In : Journal of Immunology. 147, 9, p. 3180-3184 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Chromosome 14 contains determinants that regulate susceptibility to Theiler's virus-induced demyelination in the mouse

Bureau, J. F., Drescher, K. M., Pease, L. R., Vikoren, T., Delcroix, M., Zoecklein, L., Brahic, M. & Rodriguez, M., Apr 1 1998, In : Genetics. 148, 4, p. 1941-1949 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Cigarette smoke-induced oxidative stress suppresses generation of dendritic cell IL-12 and IL-23 through ERK-dependent pathways

Kroening, P. R., Barnes, T. W., Pease, L., Limper, A., Kita, H. & Vassallo, R., Jul 15 2008, In : Journal of Immunology. 181, 2, p. 1536-1547 12 p.

Research output: Contribution to journalArticle

Open Access
66 Scopus citations