Khashayarsha Khazaie, PhD

  • 8213 Citations
  • 46 Scopus h-Index
1984 …2020

Research output per year

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Research Output

  • 8213 Citations
  • 46 Scopus h-Index
  • 95 Article
  • 10 Review article
  • 4 Comment/debate
  • 1 Chapter
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Article
1984

The accuracy of Qβ RNA translation: 2. Errors during the synthesis of Qβ proteins by cell‐free Escherichia coli extracts

KHAZAIE, K., BUCHANAN, J. H. & ROSENBERGER, R. F., Nov 1984, In : European Journal of Biochemistry. 144, 3, p. 491-495 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

The accuracy of Qβ RNA translation: 1. Errors during the synthesis of Qβ proteins by intact Escherichia coli cells

KHAZAIE, K., BUCHANAN, J. H. & ROSENBERGER, R. F., Nov 1984, In : European Journal of Biochemistry. 144, 3, p. 485-489 5 p.

Research output: Contribution to journalArticle

20 Scopus citations
1985

Differential expression of human globin genes introduced in K562 cells.

Kioussis, D., Wilson, F., Khazaie, K. & Grosveld, F., Apr 1985, In : The EMBO journal. 4, 4, p. 927-931 5 p.

Research output: Contribution to journalArticle

17 Scopus citations
1986

β-globin gene promoter generates 5′ truncated transcripts in the embryonic/fetal erythroid environment

Khazaie, K., Gounari, F., Antoniou, M., Deboer, E. & Grosveld, F., Sep 11 1986, In : Nucleic acids research. 14, 18, p. 7199-7212 14 p.

Research output: Contribution to journalArticle

4 Scopus citations
1987

Gene reactivation: a tool for the isolation of mammalian DNA methylation mutants.

Gounari, F., Banks, G. R., Khazaie, K., Jeggo, P. A. & Holliday, R., Nov 1987, In : Genes & development. 1, 9, p. 899-912 14 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations
1988

Truncation of the human EGF receptor leads to differential transforming potentials in primary avian fibroblasts and erythroblasts.

Khazaie, K., Dull, T. J., Graf, T., Schlessinger, J., Ullrich, A., Beug, H. & Vennström, B., Oct 1988, In : The EMBO journal. 7, 10, p. 3061-3071 11 p.

Research output: Contribution to journalArticle

75 Scopus citations
1990

Ectopic expression of the erythrocyte band 3 anion exchange protein, using a new avian retrovirus vector

Fuerstenberg, S., Beug, H., Introna, M., Khazaie, K., Munoz, A., Ness, S., Nordstrom, K., Sap, J., Stanley, I., Zenke, M. & Vennstrom, B., 1990, In : Journal of virology. 64, 12, p. 5891-5902 12 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations
1991

EGF promotes in vivo tumorigenic growth of primary chicken embryo fibroblasts expressing v-myc and enhances in vitro transformation by the v-erbA oncogene

Khazaie, K., Panayotou, G., Aguzzi, A., Samarut, J., Gazzolo, L. & Jurdic, P., Feb 7 1991, In : Oncogene. 6, 1, p. 21-28 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
1992

Ligand-induced activation of epidermal growth factor receptor in intact rat mammary adenocarcinoma cells without detectable receptor phosphorylation

Lichtner, R. B., Wiedemuth, M., Kittmann, A., Ullrich, A., Schirrmacher, V. & Khazaie, K., Jan 1 1992, In : Journal of Biological Chemistry. 267, 17, p. 11872-11880 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
1993

EGF receptor in neoplasia and metastasis

Khazaie, K., Schirrmacher, V. & Lichtner, R. B., Sep 1993, In : Cancer and Metastasis Reviews. 12, 3-4, p. 255-274 20 p.

Research output: Contribution to journalArticle

261 Scopus citations
1994

Expression of epidermal growth factor receptor correlates with metastatic potential of 13762NF rat mammary adenocarcinoma cells

Kaufmann, A. M., Khazaie, K., Wiedemuth, M., Rohde-Schulz, B., Ullrich, A., Schirrmacher, V. & Lichtner, R. B., 1994, In : International journal of oncology. 4, 6, p. 1149-1155 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Persistence of dormant tumor cells in the bone marrow of tumor cell- vaccinated mice correlates with long-term immunological protection

Khazaie, K., Prifti, S., Beckhove, P., Griesbach, A., Russell, S., Collins, M. & Schirrmacher, V., Aug 10 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 16, p. 7430-7434 5 p.

Research output: Contribution to journalArticle

Open Access
89 Scopus citations
1995

Immediate effects of reversible HTLV-1 tax function: T-cell activation and apoptosis

Chlichlia, K., Moldenhauer, G., Daniel, P. T., Busslinger, M., Gazzolo, L., Schirrmacher, V. & Khazaie, K., Jan 1 1995, In : Oncogene. 10, 2, p. 269-277 9 p.

Research output: Contribution to journalArticle

83 Scopus citations

Ligand mediated activation of ectopic EGF receptor promotes matrix protein adhesion and lung colonization of rat mammary adenocarcinoma cells

Lichtner, R. B., Kaufmann, A. M., Kittmann, A., Rohde-Schulz, B., Walter, J., Williams, L., Ullrich, A., Schirrmacher, V. & Khazaie, K., 1995, In : Oncogene. 10, 9, p. 1823-1832 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Lines of Murine Oligodendroglial Precursor Cells Immortalized by an Activated neu Tyrosine Kinase Show Distinct Degrees of Interaction with Axons In Vitro and In Vivo

Jung, M., Krämer, E., Grzenkowski, M., Tang, K., Blakemore, W., Aguzzi, A., Khazaie, K., Chlichlia, K., von Blankenfeld, G., Kettenmann, H. & Trotter, J., Jun 1995, In : European Journal of Neuroscience. 7, 6, p. 1245-1265 21 p.

Research output: Contribution to journalArticle

183 Scopus citations
1996

Induction of apoptosis by EGF receptor in rat mammary adenocarcinoma cells coincides with enhanced spontaneous tumour metastasis

Kaufmann, A. M., Lichtner, R. B., Schirrmacher, V. & Khazaie, K., 1996, In : Oncogene. 13, 11, p. 2349-2358 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
1997

ICE-proteases mediate HTLV-I tax-induced apoptotic T-cell death

Chlichlia, K., Busslinger, M., Peter, M. E., Walczak, H., Krammer, P. H., Schirrmacher, V. & Khazaie, K., Jan 1 1997, In : Oncogene. 14, 19, p. 2265-2272 8 p.

Research output: Contribution to journalArticle

Open Access
47 Scopus citations
4 Scopus citations

The activation domain of a hormone inducible HTLV-1 Rex protein determines colocalization with the nuclear pore

Rehberger, S., Gounari, F., Ducdodon, M., Chlichlia, K., Gazzolo, L., Schirrmacher, V. & Khazaie, K., Jun 15 1997, In : Experimental Cell Research. 233, 2, p. 363-371 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
1998

EblacZ tumor dormancy in bone marrow and lymph nodes: Active control of proliferating tumor cells by CD8+ immune T cells

Müller, M., Gounari, F., Prifti, S., Hacker, H. J., Schirrmacher, V. & Khazaie, K., Dec 1 1998, In : Cancer research. 58, 23, p. 5439-5446 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

Ganciclovir uptake in human mammary carcinoma cells expressing herpes simplex virus thymidine kinase

Haberkorn, U., Khazaie, K., Morr, I., Altmann, A., Müller, M. & Van Kaick, G., May 1 1998, In : Nuclear Medicine and Biology. 25, 4, p. 367-373 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Human T cell leukemia virus-I (HTLV-I) tax-mediated apoptosis in activated T cells requires an enhanced intracellular prooxidant state

Los, M., Khazaie, K., Schulze-Osthoff, K., Baeuerle, P. A., Schirrmacher, V. & Chlichlia, K., Sep 15 1998, In : Journal of Immunology. 161, 6, p. 3050-3055 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Modulation of elongation factor-1 delta (EF-1δ) expression by oncogenes in human epithelial cells

Kolettas, E., Lymboura, M., Khazaie, K. & Luqmani, Y., Jan 1 1998, In : Anticancer research. 18, 1 A, p. 385-392 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Nucleocytoplasmic transport of HTLV-1 RNA is regulated by two independent LTR encoded nuclear retention elements

King, J. A., Bridger, J. M., Löchelt, M., Lichter, P., Schulz, T. F., Schirrmacher, V. & Khazaie, K., Jun 25 1998, In : Oncogene. 16, 25, p. 3309-3316 8 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Prevention of EGF-modulated adhesion of tumor cells to matrix proteins by specific EGF receptor inhibition

Genersch, E., Schneider, D. W., Sauer, G., Khazaie, K., Schuppan, D. & Lichtner, R. B., Jan 19 1998, In : International Journal of Cancer. 75, 2, p. 205-209 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Suppression of ruffling by the EGF receptor in chemotactic cells

Wyckoff, J. B., Insel, L., Khazaie, K., Lichtner, R. B., Condeelis, J. S. & Segall, J. E., Jul 10 1998, In : Experimental Cell Research. 242, 1, p. 100-109 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

The extended packaging sequence of MoMLV contains a constitutive mRNA nuclear export function

King, J. A., Bridger, J. M., Gounari, F., Lichter, P., Schulz, T. F., Schirrmacher, V. & Khazaie, K., Sep 4 1998, In : FEBS Letters. 434, 3, p. 367-371 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
1999

Quantitative detection of lac-Z-transfected CC531 colon carcinoma cells in an orthotopic rat liver metastasis model

Wittmer, A., Khazaie, K. & Berger, M. R., Dec 1 1999, In : Clinical and Experimental Metastasis. 17, 5, p. 369-376 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2001

Human T cell leukemia virus type I tax enhances IL-4 gene expression in T cells

Li-Weber, M., Giaisi, M., Chlichlia, K., Khazaie, K. & Krammer, P. H., Oct 8 2001, In : European Journal of Immunology. 31, 9, p. 2623-2632 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Somatic activation of β-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development

Gounari, F., Aifantis, I., Khazaie, K., Hoeflinger, S., Harada, N., Taketo, M. M. & Von Boehmer, H., Jan 1 2001, In : Nature immunology. 2, 9, p. 863-869 7 p.

Research output: Contribution to journalArticle

147 Scopus citations
2002

Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias

Miyoshi, K., Shillingford, J. M., Le Provost, F., Gounari, F., Bronson, R., Von Boehmer, H., Taketo, M. M., Cardiff, R. D., Hennighausen, L. & Khazaie, K., Jan 8 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 1, p. 219-224 6 p.

Research output: Contribution to journalArticle

101 Scopus citations

Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice

Marten, K., Bremer, C., Khazaie, K., Sameni, M., Sloane, B., Tung, C. H. & Weissleder, R., Jan 1 2002, In : Gastroenterology. 122, 2, p. 406-414 9 p.

Research output: Contribution to journalArticle

185 Scopus citations

Redox events in HTLV-1 tax-induced apoptotic T-cell death

Chlichlia, K., Los, M., Schulze-Osthoff, K., Gazzolo, L., Schirrmacher, V. & Khazaie, K., Jan 1 2002, In : Antioxidants and Redox Signaling. 4, 3, p. 471-477 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Stabilization of β-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia

Gounari, F., Signoretti, S., Bronson, R., Klein, L., Sellers, W. R., Kum, J., Siermann, A., Taketo, M. M., Von Boehmer, H. & Khazaie, K., Jan 1 2002, In : Oncogene. 21, 26, p. 4099-4107 9 p.

Research output: Contribution to journalArticle

89 Scopus citations
2003

In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro

Klein, L., Khazaie, K. & Von Boehmer, H., Jul 22 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 15, p. 8886-8891 6 p.

Research output: Contribution to journalArticle

337 Scopus citations

Miniaturized Multichannel Near Infrared Endoscope for Mouse Imaging

Funovics, M. A., Alencar, H., Su, H. S., Khazaie, K., Weissleder, R. & Mahmood, U., Oct 1 2003, In : Molecular Imaging. 2, 4, p. 350-357 8 p.

Research output: Contribution to journalArticle

62 Scopus citations
2004

Gene transfer and genetic modification of embryonic stem cells by Cre- and Cre-PR-expressing MESV-based retroviral vectors

Psarras, S., Karagianni, N., Kellendonk, C., Tronche, F., Cosset, F. L., Stocking, C., Schirrmacher, V., von Boehmer, H. & Khazaie, K., Jan 1 2004, In : Journal of Gene Medicine. 6, 1, p. 32-42 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2005

Detection of dysplastic intestinal adenomas using a fluorescent folate imaging probe

Chen, W. T., Khazaie, K., Zhang, G., Weissleder, R. & Tung, C. H., Dec 1 2005, In : Molecular Imaging. 4, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Inducing and expanding regulatory T cell populations by foreign antigen

Kretschmer, K., Apostolou, I., Hawiger, D., Khazaie, K., Nussenzweig, M. C. & von Boehmer, H., Dec 1 2005, In : Nature immunology. 6, 12, p. 1219-1227 9 p.

Research output: Contribution to journalArticle

951 Scopus citations

Loss of adenomatous polyposis coli gene function disrupts thymic development

Gounari, F., Chang, R., Cowan, J., Guo, Z., Dose, M., Gounaris, E. & Khazaie, K., Aug 1 2005, In : Nature immunology. 6, 8, p. 800-809 10 p.

Research output: Contribution to journalArticle

79 Scopus citations

Novel adenomatous polyposis coli gene promoter is located 40 kb upstream of the initiating methionine

Karagianni, N., Ly, M. C., Psarras, S., Chlichlia, K., Schirrmacher, V., Gounari, F. & Khazaie, K., Feb 1 2005, In : Genomics. 85, 2, p. 231-237 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Nuclear RNAs confined to a reticular compartment between chromosome territories

Bridger, J. M., Kalla, C., Wodrich, H., Weitz, S., King, J. A., Khazaie, K., Kräusslich, H. G. & Lichter, P., Jan 15 2005, In : Experimental Cell Research. 302, 2, p. 180-193 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-β signals in vivo

Chen, M. L., Pittet, M. J., Gorelik, L., Flavell, R. A., Weissleder, R., Von Boehmer, H. & Khazaie, K., Jan 11 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 2, p. 419-424 6 p.

Research output: Contribution to journalArticle

538 Scopus citations
2006

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

Dose, M., Khan, I., Guo, Z., Kovalovsky, D., Krueger, A., Von Boehmer, H., Khazaie, K. & Gounari, F., Oct 15 2006, In : Blood. 108, 8, p. 2669-2677 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage

Cabarrocas, J., Cassan, C., Magnusson, F., Piaggio, E., Mars, L., Derbinski, J., Kyewski, B., Gross, D. A., Salomon, B. L., Khazaie, K., Saoudi, A. & Liblau, R. S., May 30 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 22, p. 8453-8458 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Regulatory T Cells Reversibly Suppress Cytotoxic T Cell Function Independent of Effector Differentiation

Mempel, T. R., Pittet, M. J., Khazaie, K., Weninger, W., Weissleder, R., von Boehmer, H. & von Andrian, U. H., Jul 1 2006, In : Immunity. 25, 1, p. 129-141 13 p.

Research output: Contribution to journalArticle

353 Scopus citations
2007

Mast cells are an essential hematopoietic component for polyp development

Gounaris, E., Erdman, S. E., Restaino, C., Gurish, M. F., Friend, D. S., Gounari, F., Lee, D. M., Zhang, G., Glickman, J. N., Shin, K., Rao, V. P., Poutahidis, T., Weissleder, R., McNagny, K. M. & Khazaie, K., Dec 11 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 50, p. 19977-19982 6 p.

Research output: Contribution to journalArticle

189 Scopus citations

β-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformation

Guo, Z., Dose, M., Kovalovsky, D., Chang, R., O'Neil, J., Look, A. T., Von Boehmer, H., Khazaie, K. & Gounari, F., Jun 15 2007, In : Blood. 109, 12, p. 5463-5472 10 p.

Research output: Contribution to journalArticle

87 Scopus citations
2008

Cathepsin B is involved in the trafficking of TNF-α-containing vesicles to the plasma membrane in macrophages

Ha, S. D., Martins, A., Khazaie, K., Han, J., Chan, B. M. C. & Kim, S. O., 2008, In : Journal of Immunology. 181, 1, p. 690-697 8 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Direct Presentation of Antigen by Lymph Node Stromal Cells Protects Against CD8 T-Cell-Mediated Intestinal Autoimmunity

Magnusson, F. C., Liblau, R. S., von Boehmer, H., Pittet, M. J., Lee, J. W., Turley, S. J. & Khazaie, K., Apr 2008, In : Gastroenterology. 134, 4, p. 1028-1037 10 p.

Research output: Contribution to journalArticle

63 Scopus citations