Research output

Research output per year 2000 2005 2006 2007 2008 2009 2011 2012 2013 2014 2015 2017 2018 2019 2020 2021 2022 2023 2024

• 497 Article
• 28 Review article
• 18 Comment/debate
• 18 Letter
• 18 More
  • 14 Chapter
  • 3 Editorial
  • 1 Conference contribution

Research output per year

Research output per year

Search results

• 2024

  Altered structural and functional connectivity in Posterior Cortical Atrophy and Dementia with Lewy bodies

  Singh, N. A., Goodrich, A. W., Graff-Radford, J., Machulda, M. M., Sintini, I., Carlos, A. F., Robinson, C. G., Reid, R. I., Lowe, V. J., Jack, C. R., Petersen, R. C., Boeve, B. F., Josephs, K. A., Kantarci, K. & Whitwell, J. L., Apr 15 2024, In: NeuroImage. 290, 120564.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atrophy 68%
  • Diffusion Tensor Imaging 29%
  • Linear Models 20%
  • Amyloid 18%
  • White Matter 17%

• Behavioral and Neuropsychiatric Differences Across Two Atypical Alzheimer’s Disease Variants: Logopenic Progressive Aphasia and Posterior Cortical Atrophy

  Robinson, C. G., Coleman, T., Buciuc, M., Singh, N. A., Thu Pham, N. T., Machulda, M. M., Graff-Radford, J., Whitwell, J. L. & Josephs, K. A., Jan 16 2024, In: Journal of Alzheimer's Disease. 97, 2, p. 895-908 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • speech disorder 100%
  • Aphasia 95%
  • dementia 83%
  • Atrophy 72%
  • Alzheimer Disease 64%

• Characterizing Speech Errors Across Primary Progressive Apraxia of Speech Subtypes

  Tetzloff, K. A., Duffy, J. R., Clark, H., Josephs, K. A., Whitwell, J. L. & Utianski, R. L., Mar 2024, In: Journal of Speech, Language, and Hearing Research. 67, 3, p. 811-820 10 p.

  Research output: Contribution to journal › Article › peer-review

• Clinicopathologic features of a novel star-shaped transactive response DNA-binding protein 43 (TDP-43) pathology in the oldest old

  Carlos, A. F., Sekiya, H., Koga, S., Gatto, R. G., Casey, M. C., Pham, N. T. T., Sintini, I., Machulda, M. M., Jack, C. R., Lowe, V. J., Whitwell, J. L., Petrucelli, L., Reichard, R. R., Petersen, R. C., Dickson, D. W. & Josephs, K. A., Jan 1 2024, In: Journal of Neuropathology and Experimental Neurology. 83, 1, p. 36-52 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Aged, 80 and over 100%
  • DNA-Binding Proteins 91%
  • Pathology 51%
  • Amygdala 13%
  • Neuroimaging 12%

• Combined assessment of progressive apraxia of speech brain microstructure by diffusion tensor imaging tractography and multishell neurite orientation dispersion and density imaging

  Gatto, R. G., Meade, G., Duffy, J. R., Clark, H. M., Utianski, R. L., Botha, H., Machulda, M. M., Josephs, K. A. & Whitwell, J. L., Jan 2024, In: Brain and behavior. 14, 1, e3346.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apraxias 100%
  • Diffusion Tensor Imaging 85%
  • Neurites 83%
  • White Matter 38%
  • Brain 36%

• Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis

  PCA International Work Group, Feb 2024, In: The Lancet Neurology. 23, 2, p. 168-177 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atrophy 100%
  • Data Analysis 85%
  • Meta-Analysis 85%
  • Cohort Studies 78%
  • Biomarkers 74%

• Diffusion tensor imaging-based multi-fiber tracking reconstructions can regionally differentiate phonetic versus prosodic subtypes of progressive apraxia of speech

  Gatto, R. G., Martin, P. R., Utianski, R. L., Duffy, J. R., Clark, H. M., Botha, H., Machulda, M. M., Josephs, K. A. & Whitwell, J. L., Feb 2024, In: Cortex. 171, p. 272-286 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Apraxias 100%
  • Phonetics 94%
  • Diffusion Tensor Imaging 85%
  • phonetics 80%
  • reconstruction 66%

• Direct comparison between ¹⁸F-Flortaucipir tau PET and quantitative susceptibility mapping in progressive supranuclear palsy

  Satoh, R., Ali, F., Botha, H., Lowe, V. J., Josephs, K. A. & Whitwell, J. L., Feb 1 2024, In: NeuroImage. 286, 120509.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 100%
  • Progressive Supranuclear Palsy 75%
  • Red Nucleus 13%
  • Subthalamic Nucleus 11%
  • Globus Pallidus 11%

• Letter to the editor on: Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions by Park et al. (2022)

  Luo, H., Gustavsson, E. K., Macpherson, H., Dominik, N., Zhelcheska, K., Montgomery, K., Anderson, C., Yau, W. Y., Efthymiou, S., Turner, C., DeTure, M., Dickson, D. W., Josephs, K. A., Revesz, T., Lashley, T., Halliday, G., Rowe, D. B., McCann, E., Blair, I., Lees, A. J., & 12 othersTienari, P. J., Suomalainen, A., Molina-Porcel, L., Kovacs, G. G., Gelpi, E., Hardy, J., Haltia, M. J., Tucci, A., Jaunmuktane, Z., Ryten, M., Houlden, H. & Chen, Z., Dec 2024, In: Acta Neuropathologica Communications. 12, 1, 2.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Longitudinal default mode sub-networks in the language and visual variants of Alzheimer s disease

  Sintini, I., Corriveau-Lecavalier, N., Jones, D. T., Machulda, M. M., Gunter, J. L., Schwarz, C. G., Botha, H., Carlos, A. F., Kamykowski, M. G., Atulkumar Singh, N., Petersen, R. C., Jack, C. R., Lowe, V. J., Graff-Radford, J., Josephs, K. A. & Whitwell, J. L., 2024, In: Brain Communications. 6, 2, fcae005.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Language 100%
  • Alzheimer Disease 97%
  • Amyloid 23%
  • Magnetic Resonance Imaging 16%
  • 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 14%

• Prosopagnosia: face blindness and its association with neurological disorders

  Josephs, K. A. & Josephs, K. A., 2024, In: Brain Communications. 6, 1, fcae002.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hereditary Prosopagnosia 100%
  • Prosopagnosia 83%
  • Nervous System Diseases 49%
  • Temporal Lobe 13%
  • Facial Recognition 11%

• Senile plaque-associated transactive response DNA-binding protein 43 in Alzheimer's disease: A case report spanning 16 years of memory loss

  Carlos, A. F., Koga, S., Graff-Radford, N. R., Baker, M. C., Rademakers, R., Ross, O. A., Dickson, D. W. & Josephs, K. A., Apr 2024, In: Neuropathology. 44, 2, p. 115-125 11 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA-Binding Proteins 100%
  • Amyloid Plaques 97%
  • Memory Disorders 94%
  • Alzheimer Disease 69%
  • Frontotemporal Dementia 30%

• Significance of a positive tau PET scan with a negative amyloid PET scan

  Robinson, C. G., Lee, J., Min, P. H., Przybelski, S. A., Josephs, K. A., Jones, D. T., Graff-Radford, J., Boeve, B. F., Knopman, D. S., Jack, C. R., Petersen, R. C., Machulda, M. M., Fields, J. A. & Lowe, V. J., Mar 2024, In: Alzheimer's and Dementia. 20, 3, p. 1923-1932 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Amyloid 100%
  • Positron-Emission Tomography 98%
  • Sensitivity Training Groups 90%
  • Wechsler Memory Scale 77%
  • Memory 77%

• The MAPT P.G324L and P.A406G mutations are associated with progressive supranuclear palsy with atypical features

  Badihian, N., Ali, F., Botha, H., Savica, R., Machulda, M. M., Clark, H. M., Stierwalt, J. A. G., Pham, N. T. T., Baker, M. C., Rademakers, R., Lowe, V., Whitwell, J. L. & Josephs, K. A., Feb 2024, In: Parkinsonism and Related Disorders. 119, 105962.

  Research output: Contribution to journal › Article › peer-review

  • Progressive supranuclear palsy atypical 100%
  • Microtubule-Associated Proteins 62%
  • Progressive Supranuclear Palsy 56%
  • Mutation 29%
  • 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 27%

• TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia

  Marks, J. D., Ayuso, V. E., Carlomagno, Y., Yue, M., Todd, T. W., Hao, Y., Li, Z., McEachin, Z. T., Shantaraman, A., Duong, D. M., Daughrity, L. M., Jansen-West, K., Shao, W., Calliari, A., Bejarano, J. G., DeTure, M., Rawlinson, B., Casey, M. C., Lilley, M. T., Donahue, M. H., & 16 othersJawahar, V. M., Boeve, B. F., Petersen, R. C., Knopman, D. S., Oskarsson, B., Graff-Radford, N. R., Wszolek, Z. K., Dickson, D. W., Josephs, K. A., Qi, Y. A., Seyfried, N. T., Ward, M. E., Zhang, Y. J., Prudencio, M., Petrucelli, L. & Cook, C. N., Jan 17 2024, In: Science translational medicine. 16, 730, eadf9735.

  Research output: Contribution to journal › Article › peer-review

  • Frontotemporal Dementia 100%
  • Single Nucleotide Polymorphism 67%
  • Pathology 50%
  • Proteins 29%
  • Frontotemporal Lobar Degeneration 28%
• 2023

  A Case of Atypical Alzheimer's Disease With Clinical Manifestation That Straddled the Boundary Between Primary Progressive Aphasia and Posterior Cortical Atrophy

  Chandregowda, A., Clark, H. M., Machulda, M. M., Pham, N. T. T., Lowe, V. J., Josephs, K. A. & Whitwell, J. L., May 18 2023, In: Neurologist. 28, 3, p. 195-197 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Primary Progressive Aphasia 100%
  • Atrophy 57%
  • Alzheimer Disease 51%
  • Gerstmann Syndrome 39%
  • Anomia 33%

• Altered within- and between-network functional connectivity in atypical Alzheimer's disease

  Singh, N. A., Martin, P. R., Graff-Radford, J., Sintini, I., Machulda, M. M., Duffy, J. R., Gunter, J. L., Botha, H., Jones, D. T., Lowe, V. J., Jack, C. R., Josephs, K. A. & Whitwell, J. L., 2023, In: Brain Communications. 5, 4, fcad184.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Aphasia 100%
  • Language 96%
  • Alzheimer Disease 94%
  • Atrophy 91%
  • Phenotype 73%

• Amyloid and Tau PET Positivity in Progressive Agrammatic Aphasia and Apraxia of Speech

  Tetzloff, K. A., Duffy, J. R., Clark, H. M., Pham, N. T. T., MacHulda, M. M., Botha, H., Jack, C. R., Dickson, D. W., Lowe, V. J., Josephs, K. A., Whitwell, J. L. & Utianski, R. L., Dec 6 2023, In: Journal of Alzheimer's Disease. 96, 4, p. 1759-1765 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apraxias 100%
  • speech disorder 90%
  • Aphasia 86%
  • Amyloid 71%
  • dementia 60%

• Antiphospholipid syndrome mimicking posterior cortical atrophy and the “railroad track” sign on brain fluorodeoxyglucose-positron emission tomography

  Carlos, A. F., Graff-Radford, J., Crum, B. A., Machulda, M. M., Pham, N. T. T., Lowe, V. J., Whitwell, J. L. & Josephs, K. A., May 15 2023, In: Journal of the neurological sciences. 448, 120615.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• An Update on Apraxia of Speech

  Utianski, R. L. & Josephs, K. A., Jul 2023, In: Current neurology and neuroscience reports. 23, 7, p. 353-359 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Apraxias 100%
  • Primary Progressive Nonfluent Aphasia 21%
  • Speech Intelligibility 17%
  • Tauopathies 17%
  • Speech Disorders 16%

• APOE ε4 influences medial temporal atrophy and tau deposition in atypical Alzheimer's disease

  Singh, N. A., Tosakulwong, N., Graff-Radford, J., Machulda, M. M., Pham, N. T. T., Sintini, I., Weigand, S. D., Schwarz, C. G., Senjem, M. L., Carrasquillo, M. M., Ertekin-Taner, N., Jack, C. R., Lowe, V. J., Josephs, K. A. & Whitwell, J. L., Mar 2023, In: Alzheimer's and Dementia. 19, 3, p. 784-796 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Apolipoprotein E4 100%
  • dementia 73%
  • Atrophy 63%
  • Alzheimer Disease 57%
  • Entorhinal Cortex 45%

• APOE ε4 influences within and between network functional connectivity in posterior cortical atrophy and logopenic progressive aphasia

  Singh, N. A., Martin, P. R., Graff-Radford, J., Machulda, M. M., Carrasquillo, M. M., Ertekin-Taner, N., Josephs, K. A. & Whitwell, J. L., Sep 2023, In: Alzheimer's and Dementia. 19, 9, p. 3858-3866 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoprotein E4 100%
  • speech disorder 88%
  • Aphasia 84%
  • Apolipoproteins E 65%
  • Atrophy 63%

• Assessing Patients and Care Partner Ratings of Communication-Related Participation Restrictions: Insights From Degenerative Disease

  Utianski, R. L., Martin, P. R., Duffy, J. R., Clark, H. M., Stierwalt, J. A. G., Botha, H., Ali, F., Whitwell, J. L. & Josephs, K. A., Aug 2023, In: American journal of speech-language pathology. 32, 4S, p. 1793-1805 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Interpersonal Relations 100%
  • Rating 91%
  • Patient Care 73%
  • rating 69%
  • Participation 64%

• Cancer in pathologically confirmed multiple system atrophy

  Cheshire, W. P., Koga, S., Tipton, P. W., Sekiya, H., Ross, O. A., Uitti, R. J., Josephs, K. A. & Dickson, D. W., Aug 2023, In: Clinical Autonomic Research. 33, 4, p. 451-458 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Multiple System Atrophy 100%
  • Synucleins 38%
  • Neoplasms 24%
  • Breast Neoplasms 21%
  • Inclusion Bodies 9%

• Clinicopathological associations of hemispheric dominance in primary progressive apraxia of speech

  Robinson, C. G., Duffy, J. R., Clark, H. A., Utianski, R. L., Machulda, M. M., Botha, H., Singh, N. A., Pham, N. T. T., Ertekin-Taner, N., Dickson, D. W., Lowe, V. J., Whitwell, J. L. & Josephs, K. A., May 2023, In: European Journal of Neurology. 30, 5, p. 1209-1219 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apraxias 100%
  • Motor Cortex 30%
  • Positron-Emission Tomography 21%
  • Dopamine Plasma Membrane Transport Proteins 18%
  • ioflupane 13%

• Clinicoradiologic and Neuropathologic Evaluation of Corticobasal Syndrome

  Shir, D., Pham, N. T. T., Botha, H., Koga, S., Kouri, N., Ali, F., Knopman, D. S., Petersen, R. C., Boeve, B. F., Kremers, W. K., Nguyen, A. T., Murray, M. E., Reichard, R. R., Dickson, D. W., Graff-Radford, N., Josephs, K. A., Whitwell, J. & Graff-Radford, J., Jul 18 2023, In: Neurology. 101, 3, p. E289-E299

  Research output: Contribution to journal › Article › peer-review

  • Alzheimer Disease 69%
  • Progressive Supranuclear Palsy 59%
  • Alzheimer Disease 9 39%
  • Neuropathology 37%
  • Frontotemporal Lobar Degeneration 31%

• Comparative assessment of regional tau distribution by Tau-PET and Post-mortem neuropathology in a representative set of Alzheimer's & frontotemporal lobar degeneration patients

  Gatto, R. G., Carlos, A. F., Reichard, R. R., Lowe, V. J., Whitwell, J. L. & Josephs, K. A., May 2023, In: PloS one. 18, 5 May, e0284182.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 100%
  • Frontotemporal Lobar Degeneration 79%
  • Neuropathology 63%
  • Tauopathies 34%
  • Alzheimer Disease 14%

• Comparison of Clinical, Genetic, and Pathologic Features of Limbic and Diffuse Transactive Response DNA-Binding Protein 43 Pathology in Alzheimer's Disease Neuropathologic Spectrum

  Carlos, A. F., Machulda, M. M., Rutledge, M. H., Nguyen, A. T., Reichard, R. R., Baker, M. C., Rademakers, R., Dickson, D. W., Petersen, R. C. & Josephs, K. A., Jun 13 2023, In: Journal of Alzheimer's Disease. 93, 4, p. 1521-1535 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA-Binding Proteins 100%
  • dementia 89%
  • pathology 86%
  • Alzheimer Disease 69%
  • Pathology 56%

• CRISPR interference to evaluate modifiers of C9ORF72-mediated toxicity in FTD

  Pickles, S., Zanetti Alepuz, D., Koike, Y., Yue, M., Tong, J., Liu, P., Zhou, Y., Jansen-West, K., Daughrity, L. M., Song, Y., DeTure, M., Oskarsson, B., Graff-Radford, N. R., Boeve, B. F., Petersen, R. C., Josephs, K. A., Dickson, D. W., Ward, M. E., Dong, L., Prudencio, M., & 2 othersCook, C. N. & Petrucelli, L., 2023, In: Frontiers in Cell and Developmental Biology. 11, 1251551.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Stathmin 100%
  • Chromosomes, Human, Pair 9 85%
  • Frontotemporal Dementia 80%
  • Clustered Regularly Interspaced Short Palindromic Repeats 74%
  • Open Reading Frames 62%

• Diffuse argyrophilic grain disease with TDP-43 proteinopathy and neuronal intermediate filament inclusion disease: FTLD with mixed tau, TDP-43 and FUS pathologies

  Koga, S., Murakami, A., Soto-Beasley, A. I., Walton, R. L., Baker, M. C., Castanedes-Casey, M., Josephs, K. A., Ross, O. A. & Dickson, D. W., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 109.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • TDP-43 Proteinopathies 100%
  • Frontotemporal Lobar Degeneration 80%
  • Cytomegalovirus Infections 63%
  • Intermediate Filaments 63%
  • Pathology 36%

• Diffusivity Changes in Posterior Cortical Atrophy and Logopenic Progressive Aphasia: A Longitudinal Diffusion Tensor Imaging Study

  Singh, N. A., Graff-Radford, J., Machulda, M. M., Pham, N. T. T., Schwarz, C. G., Reid, R. I., Lowe, V. J., Petersen, R. C., Jack, C. R., Josephs, K. A. & Whitwell, J. L., 2023, In: Journal of Alzheimer's Disease. 94, 2, p. 709-725 17 p.

  Research output: Contribution to journal › Article › peer-review

  • speech disorder 100%
  • Aphasia 95%
  • Diffusion Tensor Imaging 94%
  • White Matter 75%
  • Atrophy 72%

• Functional Connectivity From Disease Epicenters in Frontotemporal Dementia

  Agosta, F., Spinelli, E. G., Basaia, S., Cividini, C., Falbo, F., Pavone, C., Riva, N., Canu, E., Castelnovo, V., Magnani, G., Caso, F., Caroppo, P., Prioni, S., Villa, C., Tremolizzo, L., Appollonio, I., Silani, V., Josephs, K. A., Whitwell, J. & Filippi, M., May 30 2023, In: Neurology. 100, 22, p. E2290-E2303

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Frontotemporal Dementia 100%
  • Primary Progressive Aphasia 81%
  • Primary Progressive Nonfluent Aphasia 67%
  • Semantics 55%
  • Temporal Lobe 37%

• Influences of motor speech impairments on the presentation of dysphagia in progressive supranuclear palsy

  Petroi-Bock, D., Clark, H. M., Stierwalt, J. A. G., Botha, H., Ali, F., Whitwell, J. L. & Josephs, K. A., 2023, (Accepted/In press) In: International Journal of Speech-Language Pathology.

  Research output: Contribution to journal › Article › peer-review

  • Speech Impairment 89%
  • Dysphagia 85%
  • Progressive Supranuclear Palsy 69%
  • Dysarthria 55%
  • Deglutition Disorders 52%

• Longitudinal changes in dopamine transporter uptake scans in progressive apraxia of speech

  Utianski, R. L., Trang Thu Pham, N., Botha, H., Ali, F., Duffy, J. R., Clark, H. M., Lowe, V. J., Whitwell, J. L. & Josephs, K. A., Jan 2023, In: Clinical Parkinsonism and Related Disorders. 9, 100207.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apraxias 100%
  • Dopamine Plasma Membrane Transport Proteins 92%
  • Putamen 28%
  • Parkinsonian Disorders 18%
  • Aphasia 9%

• Longitudinal characterization of patients with progressive apraxia of speech without clearly predominant phonetic or prosodic speech features

  Utianski, R. L., Meade, G., Duffy, J. R., Clark, H. M., Botha, H., Machulda, M. M., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., Oct 2023, In: Brain and Language. 245, 105314.

  Research output: Contribution to journal › Article › peer-review

  • Apraxias 80%
  • Phonetics 76%
  • phonetics 65%
  • Characterization 47%
  • prognostication 16%

• Longitudinal clinical decline and baseline predictors in progressive supranuclear palsy

  Pavone, C., Weigand, S. W., Ali, F., Clark, H. M., Botha, H., Machulda, M. M., Savica, R., Pham, N. T. T., Grijalva, R. M., Schwarz, C. G., Senjem, M. L., Agosta, F., Filippi, M., Jack, C. R., Lowe, V. J., Josephs, K. A. & Whitwell, J. L., Feb 2023, In: Parkinsonism and Related Disorders. 107, 105290.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Progressive Supranuclear Palsy 100%
  • 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 30%
  • Gait 11%
  • Eye 10%
  • Cognitive Dysfunction 9%

• Longitudinal rates of atrophy and tau accumulation differ between the visual and language variants of atypical Alzheimer's disease

  Sintini, I., Graff-Radford, J., Schwarz, C. G., Machulda, M. M., Singh, N. A., Carlos, A. F., Senjem, M. L., Jr, C. R. J., Lowe, V. J., Josephs, K. A. & Whitwell, J. L., Oct 2023, In: Alzheimer's and Dementia. 19, 10, p. 4396-4406 11 p.

  Research output: Contribution to journal › Article › peer-review

  • speech disorder 100%
  • dementia 83%
  • Atrophy 72%
  • Language 66%
  • Alzheimer Disease 64%

• Magnetic Susceptibility in Progressive Supranuclear Palsy Variants, Parkinson's Disease, and Corticobasal Syndrome

  Satoh, R., Weigand, S. D., Pham, N. T. T., Ali, F., Arani, A., Senjem, M. L., Jack, C. R., Whitwell, J. L. & Josephs, K. A., Dec 2023, In: Movement Disorders. 38, 12, p. 2282-2290 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Progressive Supranuclear Palsy 100%
  • Red Nucleus 18%
  • Globus Pallidus 10%
  • Substantia Nigra 9%
  • Freezing 8%

• Mitochondrial encephalopathy with lactic-acidosis and stroke-like episodes syndrome presenting as progressive supranuclear palsy

  Hass, R. M., Whitwell, J. L., Coon, E. A., Josephs, K. A. & Ali, F., Aug 2023, In: Parkinsonism and Related Disorders. 113, 105516.

  Research output: Contribution to journal › Letter › peer-review

• Molecular fragment characteristics and distribution of tangle associated TDP-43 (TATs) and other TDP-43 lesions in Alzheimer’s disease

  Josephs, K. A., Koga, S., Tosakulwong, N., Weigand, S. D., Pham, N. T. T., Baker, M., Whitwell, J. L., Rademakers, R., Petrucelli, L. & Dickson, D. W., 2023, In: Free Neuropathology. 4, 22.

  Research output: Contribution to journal › Article › peer-review

  • DNA-Binding Proteins 100%
  • Alzheimer Disease 69%
  • Frontotemporal Lobar Degeneration 62%
  • Neurites 49%
  • Neurofibrillary Tangles 27%

• Not All Errors Are Created Equal: Evaluating The Impact of Model and Speaker Factors on ASR Outcomes in Clinical Populations

  Wiepert, D. A., Utianski, R. L., Duffy, J. R., Stricker, J. L., Barnard, L., Josephs, K. A., Whitwell, J. L., Jones, D. T. & Botha, H., 2023, 2023 IEEE Automatic Speech Recognition and Understanding Workshop, ASRU 2023. Institute of Electrical and Electronics Engineers Inc., (2023 IEEE Automatic Speech Recognition and Understanding Workshop, ASRU 2023).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Automatic Speech Recognition 100%
  • speech recognition 89%
  • Speech recognition 55%
  • abnormalities 46%
  • Transcription 41%

• Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood

  International FTD-Genomics Consortium, May 1 2023, In: Biological psychiatry. 93, 9, p. 770-779 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteomics 100%
  • Neurodegenerative Diseases 94%
  • Brain 53%
  • Pharmaceutical Preparations 45%
  • Amyotrophic Lateral Sclerosis 38%

• Publisher Correction to: Diffuse argyrophilic grain disease with TDP-43 proteinopathy and neuronal intermediate filament inclusion disease: FTLD with mixed tau, TDP-43 and FUS pathologies (Acta Neuropathologica Communications, (2023), 11, 1, (109), 10.1186/s40478-023-01611-z)

  Koga, S., Murakami, A., Soto-Beasley, A. I., Walton, R. L., Baker, M. C., Castanedes-Casey, M., Josephs, K. A., Ross, O. A. & Dickson, D. W., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 117.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • TDP-43 Proteinopathies 100%
  • Frontotemporal Lobar Degeneration 80%
  • Manuscripts 66%
  • Cytomegalovirus Infections 63%
  • Intermediate Filaments 63%

• Rate Modulation Abilities in Acquired Motor Speech Disorders

  Utianski, R. L., Duffy, J. R., Martin, P. R., Clark, H. M., Stierwalt, J. A. G., Botha, H., Ali, F., Whitwell, J. L. & Josephs, K. A., Aug 2023, In: Journal of Speech, Language, and Hearing Research. 66, 8, p. 3194-3205 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Speech Disorders 69%
  • speech disorder 62%
  • Modulation 58%
  • Dysarthria 36%
  • Aptitude 35%

• Spatial patterns of elevated magnetic susceptibility in progressive apraxia of speech

  Satoh, R., Arani, A., Senjem, M. L., Duffy, J. R., Clark, H. M., Utianski, R. L., Botha, H., Machulda, M. M., Jack, C. R., Whitwell, J. L. & Josephs, K. A., Jan 2023, In: NeuroImage: Clinical. 38, 103394.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apraxias 100%
  • Phonetics 21%
  • Red Nucleus 16%
  • Frontal Lobe 10%
  • Cerebellar Nuclei 7%

• TDP-43 pathology effect on volume and flortaucipir uptake in Alzheimer's disease

  Carlos, A. F., Tosakulwong, N., Weigand, S. D., Senjem, M. L., Schwarz, C. G., Knopman, D. S., Boeve, B. F., Petersen, R. C., Nguyen, A. T., Reichard, R. R., Dickson, D. W., Jack, C. R., Lowe, V., Whitwell, J. L. & Josephs, K. A., Jun 2023, In: Alzheimer's and Dementia. 19, 6, p. 2343-2354 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 100%
  • DNA-Binding Proteins 63%
  • dementia 56%
  • pathology 54%
  • Alzheimer Disease 43%

• TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains

  Estades Ayuso, V., Pickles, S., Todd, T., Yue, M., Jansen-West, K., Song, Y., González Bejarano, J., Rawlinson, B., DeTure, M., Graff-Radford, N. R., Boeve, B. F., Knopman, D. S., Petersen, R. C., Dickson, D. W., Josephs, K. A., Petrucelli, L. & Prudencio, M., Dec 2023, In: Molecular neurodegeneration. 18, 1, 57.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA-Binding Proteins 100%
  • Alzheimer Disease 69%
  • RNA 61%
  • Brain 43%
  • Frontotemporal Dementia 18%

• The Apraxia of Speech Rating Scale: Reliability, Validity, and Utility

  Duffy, J. R., Martin, P. R., Clark, H. M., Utianski, R. L., Strand, E. A., Whitwell, J. L. & Josephs, K. A., Mar 2023, In: American journal of speech-language pathology. 32, 2, p. 469-491 23 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apraxias 80%
  • Rating Scales 78%
  • rating scale 61%
  • Reproducibility of Results 54%
  • Interrater Reliability 27%

• The many faces of globular glial tauopathy: A clinical and imaging study

  Buciuc, M., Koga, S., Pham, N. T. T., Duffy, J. R., Knopman, D. S., Ali, F., Boeve, B. F., Graff-Radford, J., Botha, H., Lowe, V. J., Nguyen, A., Reichard, R. R., Dickson, D. W., Petersen, R. C., Whitwell, J. L. & Josephs, K. A., Feb 2023, In: European Journal of Neurology. 30, 2, p. 321-333 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tauopathies 100%
  • Neuroglia 65%
  • Clinical Studies 51%
  • Atrophy 28%
  • Parkinsonian Disorders 26%

• The Role of Clinical Assessment in the Era of Biomarkers

  Carlos, A. F. & Josephs, K. A., Jul 2023, In: Neurotherapeutics. 20, 4, p. 1001-1018 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Biomarkers 100%
  • Medicine 48%
  • Physicians 41%
  • Neurodegenerative Diseases 38%
  • Physician-Patient Relations 29%