• 13492 Citations
  • 66 Scopus h-Index
1975 …2020
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Research Output 1983 2020

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2004
56 Citations (Scopus)

Smooth muscle progenitor cells in vascular disease

Liu, C., Nath, K. A., Katusic, Z. S. & Caplice, N. M., Oct 2004, In : Trends in Cardiovascular Medicine. 14, 7, p. 288-293 6 p.

Research output: Contribution to journalArticle

Vascular Diseases
Smooth Muscle Myocytes
Stem Cells
Adventitia
Atherosclerotic Plaques
65 Citations (Scopus)

The perfusion paradox and vascular instability in sickle cell disease

Nath, K. A., Katusic, Z. S. & Gladwin, M. T., Mar 2004, In : Microcirculation. 11, 2, p. 179-193 15 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Blood Vessels
Perfusion
Sickle Hemoglobin
Heme Oxygenase-1
171 Citations (Scopus)

Transplantation of circulating endothelial progenitor cells restores endothelial function of denuded rabbit carotid arteries

He, T., Smith, L. A., Harrington, S., Nath, K. A., Caplice, N. M. & Katusic, Z. S., Oct 2004, In : Stroke. 35, 10, p. 2378-2384 7 p.

Research output: Contribution to journalArticle

Carotid Arteries
Transplantation
Rabbits
Endothelium
Endothelial Progenitor Cells
2003
151 Citations (Scopus)

Accommodation in ABO-incompatible kidney allografts, a novel mechanism of self-protection against antibody-mediated injury

Park, W. D., Grande, J. P., Ninova, D., Nath, K. A., Platt, J. L., Gloor, J. M. & Stegall, M. D., Aug 2003, In : American Journal of Transplantation. 3, 8, p. 952-960 9 p.

Research output: Contribution to journalArticle

Allografts
Transplants
Kidney
Antibodies
Wounds and Injuries
75 Citations (Scopus)

A major role for carbon monoxide as an endogenous hyperpolarizing factor in the gastrointestinal tract

Farrugia, G., Lei, S., Lin, X., Miller, S. M., Nath, K. A., Ferris, C. D., Levitt, M. & Szurszewski, J. H., Jul 8 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 14, p. 8567-8570 4 p.

Research output: Contribution to journalArticle

Carbon Monoxide
Gastrointestinal Tract
Membrane Potentials
Cell Membrane
Heme Oxygenase (Decyclizing)
78 Citations (Scopus)

Haem, haem oxygenase and ferritin in vascular endothelial cell injury

Balla, J., Vercellotti, G. M., Nath, K. A., Yachie, A., Nagy, E., Eaton, J. W. & Balla, G., Jul 1 2003, In : Nephrology Dialysis Transplantation. 18, SUPPL. 5

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
Ferritins
Heme
Endothelial Cells
Wounds and Injuries
66 Citations (Scopus)

Heme: A novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms

Kanakiriya, S. K. R., Croatt, A. J., Haggard, J. J., Ingelfinger, J. R., Tang, S. S., Alam, J. & Nath, K. A., Mar 1 2003, In : American Journal of Physiology - Renal Physiology. 284, 3 53-3

Research output: Contribution to journalArticle

Chemokine CCL2
Heme
Hemin
Heme Oxygenase-1
Messenger RNA
132 Citations (Scopus)

Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2

Alam, J., Killeen, E., Gong, P., Naquin, R., Hu, B., Stewart, D., Ingelfinger, J. R. & Nath, K. A., Apr 1 2003, In : American Journal of Physiology - Renal Physiology. 284, 4 53-4

Research output: Contribution to journalArticle

Heme Oxygenase-1
Heme
Epithelial Cells
Kidney
Genes
56 Citations (Scopus)

Increased venous proinflammatory gene expression and intimal hyperplasia in an aorto-caval fistula model in the rat

Nath, K. A., Kanakiriya, S. K. R., Grande, J. P., Croatt, A. J. & Katusic, Z. S., Jun 1 2003, In : American Journal of Pathology. 162, 6, p. 2079-2090 12 p.

Research output: Contribution to journalArticle

Tunica Intima
Venae Cavae
Arteriovenous Fistula
Fistula
Hyperplasia
20 Citations (Scopus)

Iodine toxicity treated with hemodialysis and continuous venovenous hemodiafiltration

Kanakiriya, S., De Chazal, I., Nath, K. A., Haugen, E. N., Albright, R. C. & Juncos, L. A., Mar 1 2003, In : American Journal of Kidney Diseases. 41, 3, p. 702-708 7 p.

Research output: Contribution to journalArticle

Hemodiafiltration
Iodine
Renal Dialysis
Povidone-Iodine
Mediastinitis
23 Citations (Scopus)

Low-dose angiotensin II enhances pressor responses without causing sustained hypertension

Pelaez, L. I., Manriquez, M. C., Nath, K. A., Romero, J. C. & Juncos, L. A., Oct 1 2003, In : Hypertension. 42, 4 II, p. 798-801 4 p.

Research output: Contribution to journalArticle

Plethysmography
Angiotensin II
Telemetry
Tail
Blood Pressure
4 Citations (Scopus)

Nitric Oxide Synthase Gene Transfer as a Tool to Study Biology of Endothelial Cells

Katusic, Z. S., Caplice, N. M. & Nath, K. A., Nov 2003, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 11, p. 1990-1994 5 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase
Endothelial Cells
Technology Transfer
Genes
Blood Vessels
11 Citations (Scopus)

Vitamin E prevents renal dysfunction induced by experimental chronic bile duct ligation

Ortiz, M. C., Manriquez, M. C., Nath, K. A., Lager, D. J., Romero, J. C. & Juncos, L. A., Sep 1 2003, In : Kidney International. 64, 3, p. 950-961 12 p.

Research output: Contribution to journalArticle

Bile Ducts
Vitamin E
Ligation
Kidney
F2-Isoprostanes
2002
30 Citations (Scopus)

TGF-β1 is an autocrine mediator of renal tubular epithelial cell growth and collagen IV production

Grande, J. P., Warner, G. M., Walker, H. J., Yusufi, A. N. K., Cheng, J., Gray, C. E., Kopp, J. B. & Nath, K. A., Mar 2002, In : Experimental Biology and Medicine. 227, 3, p. 171-181 11 p.

Research output: Contribution to journalArticle

Cell growth
Collagen
Epithelial Cells
Kidney
Growth
2001
42 Citations (Scopus)

Acute cholestatic liver disease protects against glycerol-induced acute renal failure in the rat

Leung, N., Croatt, A. J., Haggard, J. J., Grande, J. P. & Nath, K. A., 2001, In : Kidney International. 60, 3, p. 1047-1057 11 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Glycerol
Liver Diseases
Common Bile Duct
Kidney
106 Citations (Scopus)

Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis

Inguaggiato, P., Gonzalez-Michaca, L., Croatt, A. J., Haggard, J. J., Alam, J. & Nath, K. A., 2001, In : Kidney International. 60, 6, p. 2181-2191 11 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Up-Regulation
Apoptosis
Cell Cycle
Cycloheximide
174 Citations (Scopus)

Heme protein-induced chronic renal inflammation: Suppressive effect of induced heme oxygenase-1

Nath, K. A., Vercellotti, G. M., Grande, J. P., Miyoshi, H., Paya, C. V., Manivel, J. C., Haggard, J. J., Croatt, A. J., Payne, W. D. & Alam, J., 2001, In : Kidney International. 59, 1, p. 106-117 12 p.

Research output: Contribution to journalArticle

Hemeproteins
Heme Oxygenase-1
Inflammation
Kidney
Paroxysmal Hemoglobinuria
228 Citations (Scopus)

Increased oxidative stress in experimental renovascular hypertension

Lerman, L. O., Nath, K. A., Rodriguez-Porcel, M. G., Krier, J. D., Schwartz, R. S., Napoli, C. & Romero, J. C., 2001, In : Hypertension. 37, 2 II, p. 541-546 6 p.

Research output: Contribution to journalArticle

Renovascular Hypertension
Renin
Arterial Pressure
Oxidative Stress
Isoprostanes
135 Citations (Scopus)

Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease

Nath, K. A., Grande, J. P., Haggard, J. J., Croatt, A. J., Katusic, Z. S., Solovey, A. & Hebbel, R. P., 2001, In : American Journal of Pathology. 158, 3, p. 893-903 11 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Sickle Cell Anemia
Oxidative Stress
Kidney
Oxidants
14 Citations (Scopus)

Protective effect of heme oxygenase-1 gene transfer against oxyhemoglobin-induced endothelial dysfunction

Eguchi, D., Weiler, D., Alam, J., Nath, K. A. & Katusic, Z. S., 2001, In : Journal of Cerebral Blood Flow and Metabolism. 21, 10, p. 1215-1222 8 p.

Research output: Contribution to journalArticle

Oxyhemoglobins
Heme Oxygenase-1
Genes
Endothelium
Bradykinin
158 Citations (Scopus)

Simvastatin preserves coronary endothelial function in hypercholesterolemia in the absence of lipid lowering

Wilson, S. H., Simari, R. D., Best, P., Peterson, T. E., Lerman, L. O., Aviram, M., Nath, K. A., Holmes, D. & Lerman, A., 2001, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 21, 1, p. 122-128 7 p.

Research output: Contribution to journalArticle

Simvastatin
Hypercholesterolemia
Lipids
Vasodilation
Nitric Oxide Synthase
2000
142 Citations (Scopus)

Angiotensin ii induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitro

Haugen, E. N., Croatt, A. J. & Nath, K. A., 2000, In : Kidney International. 58, 1, p. 144-152 9 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Angiotensins
Oxidants
Angiotensin II
Kidney
3 Citations (Scopus)

Effect of γ-L-glutamyl-L-DOPA on phosphate excretion

Sadiq, S., Berndt, T. J., Nath, K. A. & Knox, F. G., Jan 2000, In : Journal of Laboratory and Clinical Medicine. 135, 1, p. 52-56 5 p.

Research output: Contribution to journalArticle

Dopamine
Phosphates
Rats
Prodrugs
Sprague Dawley Rats
74 Citations (Scopus)

Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease

Nath, K. A., Shah, V., Haggard, J. J., Croatt, A. J., Smith, L. A., Hebbel, R. P. & Katusic, Z. S., 2000, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 279, 6 48-6

Research output: Contribution to journalArticle

Sickle Cell Anemia
Transgenic Mice
Blood Vessels
Globins
Blood Pressure
43 Citations (Scopus)
Heme Oxygenase-1
Nitric Oxide Donors
Nitroprusside
Nitric Oxide
Epithelial Cells
309 Citations (Scopus)

Reactive oxygen species and acute renal failure

Nath, K. A. & Norby, S. M., Dec 1 2000, In : American Journal of Medicine. 109, 8, p. 665-678 14 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Reactive Oxygen Species
Necrosis
Kidney
Acute Kidney Tubular Necrosis
97 Citations (Scopus)

Renal response to repetitive exposure to heme proteins: Chronic injury induced by an acute insult

Nath, K. A., Croatt, A. J., Haggard, J. J. & Grande, J. P., 2000, In : Kidney International. 57, 6, p. 2423-2433 11 p.

Research output: Contribution to journalArticle

Hemeproteins
Kidney
Wounds and Injuries
Glomerular Filtration Rate
Glycerol
77 Citations (Scopus)

Role of adenosine in contrast media-induced acute renal failure in diabetes mellitus

Pflueger, A., Larson, T. S., Nath, K. A., King, B. F., Gross, J. M. & Knox, F. G., 2000, In : Mayo Clinic Proceedings. 75, 12, p. 1275-1283 9 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Adenosine
Contrast Media
Diabetes Mellitus
Kidney
218 Citations (Scopus)

The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo

Nath, K. A., Haggard, J. J., Croatt, A. J., Grande, J. P., Poss, K. D. & Alam, J., 2000, In : American Journal of Pathology. 156, 5, p. 1527-1535 9 p.

Research output: Contribution to journalArticle

Hemeproteins
Heme Oxygenase-1
Heme
Mortality
Kidney
1999
4 Citations (Scopus)
Hemeproteins
Glycerol
Arterial Pressure
Nitroprusside
Acetylcholine
45 Citations (Scopus)
Heme Oxygenase (Decyclizing)
Enzyme Induction
Heme Oxygenase-1
Gene Expression Regulation
Reperfusion Injury
111 Citations (Scopus)

The involvement of oxidative stress in the progression of renal injury

Haugen, E. & Nath, K. A., 1999, In : Blood Purification. 17, 2-3, p. 58-65 8 p.

Research output: Contribution to journalArticle

Oxidative Stress
Kidney
Wounds and Injuries
Oxidants
Chronic Renal Insufficiency
1998
88 Citations (Scopus)

Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative properties

Schwochau, G. B., Nath, K. A. & Rosenberg, M. E., 1998, In : Kidney International. 53, 6, p. 1647-1653 7 p.

Research output: Contribution to journalArticle

Clusterin
Oxidative Stress
Oxidants
LLC-PK1 Cells
Fibrinogen
203 Citations (Scopus)

Heme oxygenase: Protective gene or trojan horse

Platt, J. L. & Nath, K. A., 1998, In : Nature Medicine. 4, 12, p. 1364-1365 2 p.

Research output: Contribution to journalArticle

Chemical Models
Heme Oxygenase (Decyclizing)
Heme Oxygenase-1
Arteriosclerosis
Graft Rejection
86 Citations (Scopus)

Intracellular targets in heme protein-induced renal injury

Nath, K. A., Grande, J. P., Croatt, A. J., Likely, S., Hebbel, R. P. & Enright, H., 1998, In : Kidney International. 53, 1, p. 100-111 12 p.

Research output: Contribution to journalArticle

Hemeproteins
Heme
Mitochondria
Oxygen Consumption
Nephrons
96 Citations (Scopus)

Redox regulation of renal DNA synthesis, transforming growth factor-β1 and collagen gene expression

Nath, K. A., Grande, J. P., Croatt, A., Haugen, J., Kim, Y. & Rosenberg, M. E., 1998, In : Kidney International. 53, 2, p. 367-381 15 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Oxidation-Reduction
Collagen
Kidney
Gene Expression
148 Citations (Scopus)

The tubulointerstitium in progressive renal disease

Nath, K. A., 1998, In : Kidney International. 54, 3, p. 992-994 3 p.

Research output: Contribution to journalArticle

Intercellular Signaling Peptides and Proteins
Kidney
Wounds and Injuries
1997
35 Citations (Scopus)

CD40 inhibits B cell apoptosis by upregulating bcl-x(L) expression and blocking oxidant accumulation

Fang, W., Nath, K. A., Mackey, M. F., Noelle, R. J., Mueller, D. L. & Behrens, T. W., Mar 1997, In : American Journal of Physiology - Cell Physiology. 272, 3 41-3

Research output: Contribution to journalArticle

Oxidants
B-Lymphocytes
Cells
Apoptosis
Immunoglobulin Class Switching

Hydrogen peroxide downregulates IL-1-driven mesangial iNOS activity: Implications for glomerulonephritis

Jaimes, E. A., Nath, K. A. & Raij, L., 1997, In : American Journal of Physiology. 272, 6 PART 2

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type II
Glomerulonephritis
Interleukin-1
Hydrogen Peroxide
Down-Regulation
21 Citations (Scopus)
Nitric Oxide Synthase Type II
Glomerulonephritis
Interleukin-1
Hydrogen Peroxide
Down-Regulation
29 Citations (Scopus)

Temporal Induction of Clusterin in Cisplatin Nephrotoxicity

Silkensen, J. R., Agarwal, A., Nath, K. A., Manivel, J. C. & Rosenberg, M. E., Feb 1997, In : Journal of the American Society of Nephrology. 8, 2, p. 302-305 4 p.

Research output: Contribution to journalArticle

Clusterin
Cisplatin
Kidney
Wounds and Injuries
Creatinine
1996
2 Citations (Scopus)

Adaptation to the nephrotoxicity of heme proteins

Nath, K. A., 1996, In : Experimental Nephrology. 4, 3, p. 139-143 5 p.

Research output: Contribution to journalArticle

Hemeproteins
Physiological Adaptation
Heme Oxygenase (Decyclizing)
Enzyme Induction
Rhabdomyolysis

Endothelial processes contribute to vasoconstriction in acute renal failure (arf)

Warden, D. H. & Nath, K. A., 1996, In : Journal of Investigative Medicine. 44, 3

Research output: Contribution to journalArticle

Vasoconstriction
Acute Kidney Injury
Glycerol
Mercuric Chloride
Aorta
61 Citations (Scopus)

Gas-generating systems in acute renal allograft rejection in the rat: Co-induction of heme oxygenase and nitric oxide synthase

Agarwal, A., Kim, Y., Matas, A. J., Alam, J. & Nath, K. A., Jan 15 1996, In : Transplantation. 61, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
Nitric Oxide Synthase
Allografts
Gases
Kidney
107 Citations (Scopus)

Glomerular inflammation induces resistance to tubular injury in the rat. A novel form of acquired, heme oxygenase-dependent resistance to renal injury

Vogt, B. A., Shanley, T. P., Croatt, A., Alam, J., Johnson, K. J. & Nath, K. A., Nov 1 1996, In : Journal of Clinical Investigation. 98, 9, p. 2139-2145 7 p.

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
Inflammation
Kidney
Acute Kidney Injury
Wounds and Injuries

Heme arginate and the endothelium: mechanism for its safety in porphyria

Balla, J., Balla, G., Kakuk, G., Nath, K. A., Jacob, H. S. & Vercellolti, G. M., 1996, In : Journal of Investigative Medicine. 44, 3

Research output: Contribution to journalArticle

Porphyrias
Heme
Endothelium
Safety
Acute Intermittent Porphyria
111 Citations (Scopus)

Renal oxidant injury and oxidant response induced by mercury

Nath, K. A., Croatt, A. J., Likely, S., Behrens, T. W. & Warden, D., 1996, In : Kidney International. 50, 3, p. 1032-1043 12 p.

Research output: Contribution to journalArticle

Mercuric Chloride
Mercury
Oxidants
Kidney
Hydrogen Peroxide
75 Citations (Scopus)

Renal tubular epithelial cells mimic endothelial cells upon exposure to oxidized LDL

Agarwal, A., Balla, J., Balla, G., Croatt, A. J., Vercellotti, G. M. & Nath, K. A., 1996, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 271, 4 40-4

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
LDL Lipoproteins
Endothelial Cells
Epithelial Cells
Human Umbilical Vein Endothelial Cells
9 Citations (Scopus)
Interstitial Nephritis
Platelet-Derived Growth Factor
Disease Progression
Kidney
1995
155 Citations (Scopus)

Acquired resistance to acute oxidative stress. Possible role of heme oxygenase and ferritin

Vogt, B. A., Alam, J., Croatt, A. J., Vercellotti, G. M. & Nath, K. A., 1995, In : Laboratory Investigation. 72, 4, p. 474-483 10 p.

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
Endotoxins
Oxidative Stress
Acute Kidney Injury
Glycerol