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1975 …2020
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2011
22 Citations (Scopus)

n-3 Fatty acids block TNF-α -stimulated MCP-1 expression in rat mesangial cells

Diaz Encarnacion, M. M., Warner, G. M., Cheng, J., Gray, C. E., Nath, K. A. & Grande, J. P., May 2011, In : American Journal of Physiology - Renal Physiology. 300, 5, p. 1142-1151 10 p.

Research output: Contribution to journalArticle

Mesangial Cells
Chemotactic Factors
Omega-3 Fatty Acids
Monocytes
Eicosapentaenoic Acid
107 Citations (Scopus)

Outcomes of arteriovenous fistula creation after the fistula first initiative

Schinstock, C., Albright, R. C., Williams, A. W., Dillon, J. J., Bergstralh, E. J., Jenson, B. M., McCarthy, J. T. & Nath, K. A., Aug 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 8, p. 1996-2002 7 p.

Research output: Contribution to journalArticle

Arteriovenous Fistula
Fistula
Renal Dialysis
Hospitalization
Arteries
16 Citations (Scopus)

Regional and systemic hemodynamic responses following the creation of a murine arteriovenous fistula

Kang, L., Yamada, S., Hernandez, M. C., Croatt, A. J., Grande, J. P., Juncos, J. P., Vercellotti, G. M., Hebbel, R. P., Katusic, Z. S., Terzic, A. & Nath, K. A., Oct 2011, In : American Journal of Physiology - Renal Physiology. 301, 4

Research output: Contribution to journalArticle

Arteriovenous Fistula
Hemodynamics
Heme Oxygenase-1
Vascular Resistance
Cardiac Output
4 Citations (Scopus)

Selective enhancement of contractions to α1-adrenergic receptor activation in the aorta of mice with sickle cell disease

Juncos, R., Juncos, L., Hebbel, R. P., Vercellotti, G. M., Katusic, Z. S. & Nath, K. A., Feb 2011, In : Journal of Cardiovascular Pharmacology. 57, 2, p. 263-266 4 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Adrenergic Receptors
Aorta
Phenylephrine
Adrenergic Agents
2010
23 Citations (Scopus)

A promising approach for treatment of tumor-induced bone diseases: Utilizing bisphosphonate derivatives of nucleoside antimetabolites

Reinholz, M. M., Zinnen, S. P., Dueck, A., Dingli, D. M., Reinholz, G. G., Jonart, L. A., Kitzmann, K. A., Bruzek, A. K., Negron, V., Abdalla, A. K., Arendt, B. K., Croatt, A. J., Sanchez-Perez, L., Sebesta, D. P., Lönnberg, H., Yoneda, T., Nath, K. A., Jelinek, D. F., Russell, S. J., Ingle, J. N. & 4 others, Spelsberg, T. C., Dixon, H. B. F., Karpeisky, A. & Lingle, W. L., Jul 2010, In : Bone. 47, 1, p. 12-22 11 p.

Research output: Contribution to journalArticle

Antimetabolites
Bone Diseases
Diphosphonates
zoledronic acid
Nucleosides
38 Citations (Scopus)

Characterization of a model of an arteriovenous fistula in the rat: The effect of L-NAME

Croatt, A. J., Grande, J. P., Hernandez, M. C., Ackerman, A. W., Katusic, Z. S. & Nath, K. A., May 2010, In : American Journal of Pathology. 176, 5, p. 2530-2541 12 p.

Research output: Contribution to journalArticle

NG-Nitroarginine Methyl Ester
Arteriovenous Fistula
Hyperplasia
Renal Dialysis
Nitric Oxide Synthase
20 Citations (Scopus)

Early and prominent alterations in hemodynamics, signaling, and gene expression following renal ischemia in sickle cell disease

Juncos, J. P., Grande, J. P., Croatt, A. J., Hebbel, R. P., Vercellotti, G. M., Katusic, Z. S. & Nath, K. A., Apr 2010, In : American Journal of Physiology - Renal Physiology. 298, 4

Research output: Contribution to journalArticle

Sickle Cell Anemia
Ischemia
Hemodynamics
Kidney
Gene Expression
6 Citations (Scopus)
Heme Oxygenase (Decyclizing)
Hemodynamics
Kidney
Heme Oxygenase-1
Oxidative Stress
74 Citations (Scopus)

Hemolysis and acute kidney failure

Qian, Q., Nath, K. A., Wu, Y., Daoud, T. M. & Sethi, S. M., Oct 2010, In : American Journal of Kidney Diseases. 56, 4, p. 780-784 5 p.

Research output: Contribution to journalArticle

Hemolysis
Acute Kidney Injury
Kidney
Hemeproteins
Organelles
1 Citation (Scopus)

Receptor-mediated endocytosis is a Trojan horse in light-chain nephrotoxicity

Nath, K. A., Jul 2010, In : Journal of the American Society of Nephrology. 21, 7, p. 1065-1066 2 p.

Research output: Contribution to journalArticle

Low Density Lipoprotein Receptor-Related Protein-2
Kidney Tubules
Immunoglobulin Light Chains
Chemokine CCL2
Kidney Diseases
13 Citations (Scopus)

The role of Sirt1 in renal rejuvenation and resistance to stress

Nath, K. A., Apr 1 2010, In : Journal of Clinical Investigation. 120, 4, p. 1026-1028 3 p.

Research output: Contribution to journalArticle

Sirtuin 1
Rejuvenation
Kidney
Caloric Restriction
Cell Aging
11 Citations (Scopus)
Catenins
Arteriovenous Fistula
Metalloproteases
Glycogen Synthase Kinase 3
Matrix Metalloproteinase 9
2009
58 Citations (Scopus)
Systems Biology
Sickle Cell Anemia
Reperfusion Injury
Inflammation
Biological Phenomena
45 Citations (Scopus)

Temporal analysis of signaling pathways activated in a murine model of two-kidney, one-clip hypertension

Cheng, J., Zhou, W., Warner, G. M., Knudsen, B. E., Garovic, V. D., Gray, C. E., Lerman, L. O., Platt, J. L., Romero, J. C., Textor, S. C., Nath, K. A. & Grande, J. P., Oct 2009, In : American Journal of Physiology - Renal Physiology. 297, 4

Research output: Contribution to journalArticle

Surgical Instruments
Hypertension
Kidney
Renal Artery Obstruction
Atrophy
104 Citations (Scopus)

Vascular protection by tetrahydrobiopterin: progress and therapeutic prospects

Katusic, Z. S., d'Uscio, L. V. & Nath, K. A., Jan 2009, In : Trends in Pharmacological Sciences. 30, 1, p. 48-54 7 p.

Research output: Contribution to journalArticle

Blood Vessels
Nitric Oxide
Translational Medical Research
Nitric Oxide Synthase Type III
Peripheral Arterial Disease
2008
69 Citations (Scopus)

Dendritic cells facilitate accumulation of IL-17 T cells in the kidney following acute renal obstruction

Dong, X., Bachman, L. A., Miller, M. N., Nath, K. A. & Griffin, M. D., Nov 2008, In : Kidney International. 74, 10, p. 1294-1309 16 p.

Research output: Contribution to journalArticle

Interleukin-17
Dendritic Cells
T-Lymphocytes
Kidney
Interferons
47 Citations (Scopus)

Genetic deficiency of heme oxygenase-1 impairs functionality and form of an arteriovenous fistula in the mouse

Juncos, J. P., Tracz, M. J., Croatt, A. J., Grande, J. P., Ackerman, A. W., Katusic, Z. S. & Nath, K. A., Jul 2008, In : Kidney International. 74, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

Arteriovenous Fistula
Fistula
Heme Oxygenase-1
Matrix Metalloproteinases
Knockout Mice
19 Citations (Scopus)

Induction of Heme Oxygenase-1 and Ferritin in the Kidney in Warm Antibody Hemolytic Anemia

Fervenza, F. C., Croatt, A. J., Bittar, C. M., Rosenthal, D. W., Lager, D. J., Leung, N., Zeldenrust, S. R. & Nath, K. A., Nov 2008, In : American Journal of Kidney Diseases. 52, 5, p. 972-977 6 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Hemolytic Anemia
Autoimmune Hemolytic Anemia
Hemoglobinuria
Kidney
21 Citations (Scopus)

Induction of heme oxygenase-1 is a beneficial response in a murine model of venous thrombosis

Tracz, M. J., Juncos, J. P., Grande, J. P., Croatt, A. J., Ackerman, A. W., Katusic, Z. S. & Nath, K. A., Dec 2008, In : American Journal of Pathology. 173, 6, p. 1882-1890 9 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Venous Thrombosis
Thrombosis
Inferior Vena Cava
Ligation
9 Citations (Scopus)

Preservation of the kidney by carbon monoxide: A black swan phenomenon

Nath, K. A., Oct 2008, In : Kidney International. 74, 8, p. 989-991 3 p.

Research output: Contribution to journalArticle

Organ Preservation Solutions
Carbon Monoxide
Kidney
Wounds and Injuries
Cytochrome P-450 Enzyme System
15 Citations (Scopus)

Signaling pathways modulated by fish oil in salt-sensitive hypertension

Diaz Encarnacion, M. M., Warner, G. M., Gray, C. E., Cheng, J., Keryakos, H. K. H., Nath, K. A. & Grande, J. P., Jun 2008, In : American Journal of Physiology - Renal Physiology. 294, 6

Research output: Contribution to journalArticle

Fish Oils
Salts
Hypertension
Inbred Dahl Rats
Kidney
2007
28 Citations (Scopus)

An analysis of the DOCA-salt model of hypertension in HO-1-/- mice and the Gunn rat

Nath, K. A., D'Uscio, L. V., Juncos, J. P., Croatt, A. J., Manriquez, M. C., Pittock, S. T. & Katusic, Z. S., Jul 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 293, 1

Research output: Contribution to journalArticle

Gunn Rats
Desoxycorticosterone Acetate
Heme Oxygenase-1
Salts
Hypertension
74 Citations (Scopus)

Deficiency of heme oxygenase-1 impairs renal hemodynamics and exaggerates systemic inflammatory responses to renal ischemia

Tracz, M. J., Juncos, J. P., Croatt, A. J., Ackerman, A. W., Grande, J. P., Knutson, K. L., Kane, G. M., Terzic, A., Griffin, M. D. & Nath, K. A., Nov 2007, In : Kidney International. 72, 9, p. 1073-1080 8 p.

Research output: Contribution to journalArticle

Ischemia
Hemodynamics
Kidney
Interleukin-6
Heme Oxygenase-1
42 Citations (Scopus)

Endothelial progenitor cells stimulate cerebrovascular production of prostacyclin by paracrine activation of cyclooxygenase-2

Santhanam, A. V. R., Smith, L. A., He, T., Nath, K. A. & Katusic, Z. S., May 2007, In : Circulation Research. 100, 9, p. 1379-1388 10 p.

Research output: Contribution to journalArticle

Epoprostenol
Cyclooxygenase 2
Basilar Artery
Cerebral Arteries
Rabbits
81 Citations (Scopus)

Essential role of endothelial nitric oxide synthase in vascular effects of erythropoietin

D'Uscio, L. V., Smith, L. A., Santhanam, A. V., Richardson, D., Nath, K. A. & Katusic, Z. S., May 2007, In : Hypertension. 49, 5, p. 1142-1148 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Erythropoietin
Blood Vessels
Nitric Oxide Synthase
Carotid Arteries
31 Citations (Scopus)

Neoangiogenesis and the presence of progenitor cells in the venous limb of an arteriovenous fistula in the rat

Caplice, N. M., Wang, S., Tracz, M., Croatt, A. J., Grande, J. P., Katusic, Z. S. & Nath, K. A., Aug 2007, In : American Journal of Physiology - Renal Physiology. 293, 2

Research output: Contribution to journalArticle

Arteriovenous Fistula
Stem Cells
Extremities
Cytokines
Chemokine CXCL12
193 Citations (Scopus)

Physiology and pathophysiology of heme: Implications for kidney disease

Tracz, M. J., Alam, J. & Nath, K. A., Feb 2007, In : Journal of the American Society of Nephrology. 18, 2, p. 414-420 7 p.

Research output: Contribution to journalArticle

Kidney Diseases
Heme
Hemeproteins
Kidney
Heme Oxygenase-1
48 Citations (Scopus)

Renal hemodynamic, inflammatory, and apoptotic responses to lipopolysaccharide in HO-1-/- mice

Tracz, M. J., Juncos, J. P., Grande, J. P., Croatt, A. J., Ackerman, A. W., Rajagopalan, G., Knutson, K. L., Badley, A. D., Griffin, M. D., Alam, J. & Nath, K. A., Jun 2007, In : American Journal of Pathology. 170, 6, p. 1820-1830 11 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Lipopolysaccharides
Hemodynamics
Kidney
Cytokines
12 Citations (Scopus)

Renal response to repeated exposure to endotoxin: Implications for acute kidney injury

Nath, K. A., Mar 13 2007, In : Kidney International. 71, 6, p. 477-479 3 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Endotoxins
Cholesterol
Kidney
34 Citations (Scopus)

Renal upregulation of HO-1 reduces albumin-driven MCP-1 production: Implications for chronic kidney disease

Murali, N. S., Ackerman, A. W., Croatt, A. J., Cheng, J., Grande, J. P., Sutor, S. L., Bram, R. J., Bren, G. D., Badley, A. D., Alam, J. & Nath, K. A., Feb 2007, In : American Journal of Physiology - Renal Physiology. 292, 2

Research output: Contribution to journalArticle

Heme Oxygenase-1
Chemokine CCL2
Chronic Renal Insufficiency
Albumins
Up-Regulation
226 Citations (Scopus)

Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury

Dong, X., Swaminathan, S., Bachman, L. A., Croatt, A. J., Nath, K. A. & Griffin, M. D., Apr 2007, In : Kidney International. 71, 7, p. 619-628 10 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Dendritic Cells
Tumor Necrosis Factor-alpha
Kidney
Interleukin-6
2006
18 Citations (Scopus)

Anomalous renal effects of tin protoporphyrin in a murine model of sickle cell disease

Juncos, J. P., Grande, J. P., Murali, N., Croatt, A. J., Juncos, L. A., Hebbel, R. P., Katusic, Z. S. & Nath, K. A., Jul 2006, In : American Journal of Pathology. 169, 1, p. 21-31 11 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Kidney
Heme Oxygenase-1
Wounds and Injuries
Ischemia
217 Citations (Scopus)

Heme oxygenase-1: A provenance for cytoprotective pathways in the kidney and other tissues

Nath, K. A., Aug 21 2006, In : Kidney International. 70, 3, p. 432-443 12 p.

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
Heme Oxygenase-1
Kidney
Biliverdine
Isoenzymes
11 Citations (Scopus)

IL-10-deficiency unmasks unique immune system defects and reveals differential regulation of organ-specific autoimmunity in non-obese diabetic mice

Rajagopalan, G., Kudva, Y. C., Sen, M. M., Marietta, E. V., Murali, N., Nath, K. A., Moore, J. & David, C. S., Apr 21 2006, In : Cytokine. 34, 1-2, p. 85-95 11 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Immune system
Autoimmunity
Interleukin-10
Immune System
79 Citations (Scopus)

Increased blood flow causes coordinated upregulation of arterial eNOS and biosynthesis of tetrahydrobiopterin

Lam, C. F., Peterson, T. E., Richardson, D. M., Croatt, A. J., D'Uscio, L. V., Nath, K. A. & Katusic, Z. S., Feb 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 290, 2

Research output: Contribution to journalArticle

Nitric Oxide Synthase
Up-Regulation
Caveolin 1
Fistula
HSP90 Heat-Shock Proteins
46 Citations (Scopus)

Intranasal exposure to staphylococcal enterotoxin B elicits an acute systemic inflammatory response

Rajagopalan, G., Sen, M. M., Singh, M., Murali, N. S., Nath, K. A., Iijima, K., Kita, H., Leontovich, A. A., Gopinathan, U., Patel, R. & David, C. S., Jun 2006, In : Shock. 25, 6, p. 647-656 10 p.

Research output: Contribution to journalArticle

HLA Antigens
Transgenic Mice
Interleukin-12
Staphylococcus aureus
Biological Warfare
41 Citations (Scopus)
Cerebral Arteries
Nitric Oxide Synthase Type III
Erythropoietin
Basilar Artery
Endothelium
21 Citations (Scopus)

Proteinuria as a determinant of renal expression of heme oxygenase-1: Studies in models of glomerular and tubular proteinuria in the rat

Pedraza-Chaverri, J., Murali, N. S., Croatt, A. J., Alam, J., Grande, J. P. & Nath, K. A., Jan 2006, In : American Journal of Physiology - Renal Physiology. 290, 1

Research output: Contribution to journalArticle

Heme Oxygenase-1
Proteinuria
Kidney
Kidney Diseases
Protein Transport
2005
97 Citations (Scopus)

Antigen presentation by dendritic cells in renal lymph nodes is linked to systemic and local injury to the kidney

Dong, X., Swaminathan, S., Bachman, L. A., Croatt, A. J., Nath, K. A. & Griffin, M. D., Sep 2005, In : Kidney International. 68, 3, p. 1096-1108 13 p.

Research output: Contribution to journalArticle

Antigen Presentation
Dendritic Cells
Lymph Nodes
Kidney
Wounds and Injuries
12 Citations (Scopus)

Endogenous superantigens shape response to exogenous superantigens

Rajagopalan, G., Singh, M., Sen, M. M., Murali, N. S., Nath, K. A. & David, C. S., Sep 2005, In : Clinical and Diagnostic Laboratory Immunology. 12, 9, p. 1119-1122 4 p.

Research output: Contribution to journalArticle

Superantigens
T-cells
T-Cell Antigen Receptor
Bearings (structural)
T-Lymphocytes
35 Citations (Scopus)

Functional adaptation and remodeling of pulmonary artery in flow-induced pulmonary hypertension

Lam, C. F., Peterson, T. E., Croatt, A. J., Nath, K. A. & Katusic, Z. S., Dec 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 289, 6 58-6

Research output: Contribution to journalArticle

Pulmonary Hypertension
Pulmonary Artery
Fistula
Cyclooxygenase 2
Lung
12 Citations (Scopus)

Heart failure increases protein expression and enzymatic activity of heme oxygenase-1 in the lung

Lam, C. F., Croatt, A. J., Richardson, D. M., Nath, K. A. & Katusic, Z. S., Jan 1 2005, In : Cardiovascular Research. 65, 1, p. 203-210 8 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Heart Failure
Lung
Proteins
Fistula
80 Citations (Scopus)

MCP-1 is up-regulated in unstressed and stressed HO-1 knockout mice: Pathophysiologic correlates

Pittock, S. T., Norby, S. M., Grande, J. P., Croatt, A. J., Bren, G. D., Badley, A. D., Caplice, N. M., Griffin, M. D. & Nath, K. A., Aug 2005, In : Kidney International. 68, 2, p. 611-622 12 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Chemokine CCL2
Knockout Mice
Up-Regulation
Kidney
66 Citations (Scopus)
Sodium Azide
C-Reactive Protein
Endothelial Cells
Human Umbilical Vein Endothelial Cells
Azides
19 Citations (Scopus)

Provenance of the protective property of p21

Nath, K. A., Sep 2005, In : American Journal of Physiology - Renal Physiology. 289, 3 58-3

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase Inhibitor p21
Cell Cycle Proteins
Acute Kidney Injury
Antineoplastic Agents
Cisplatin
42 Citations (Scopus)

TGF-β1 stimulates monocyte chemoattractant protein-1 expression in mesangial cells through a phosphodiesterase isoenzyme 4-dependent process

Cheng, J., Encarnacion, M. M. D., Warner, G. M., Gray, C. E., Nath, K. A. & Grande, J. P., Oct 2005, In : American Journal of Physiology - Cell Physiology. 289, 4 58-4

Research output: Contribution to journalArticle

Type 4 Cyclic Nucleotide Phosphodiesterase
Mesangial Cells
Chemokine CCL2
Phosphoric Diester Hydrolases
Transforming Growth Factors
73 Citations (Scopus)

The hyperbilirubinemic Gunn rat is resistant to the pressor effects of angiotensin II

Pflueger, A., Croatt, A. J., Peterson, T. E., Smith, L. A., D'Uscio, L. V., Katusic, Z. S. & Nath, K. A., Mar 2005, In : American Journal of Physiology - Renal Physiology. 288, 3 57-3

Research output: Contribution to journalArticle

Gunn Rats
Angiotensin II
Bilirubin
Superoxides
Antioxidants
79 Citations (Scopus)

Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury

Nath, K. A., Grande, J. P., Croatt, A. J., Frank, E., Caplice, N. M., Hebbel, R. P. & Katusic, Z. S., Apr 2005, In : American Journal of Pathology. 166, 4, p. 963-972 10 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Transgenic Mice
Ischemia
Kidney
Sickle Cell Anemia
2004
75 Citations (Scopus)

Heme: A determinant of life and death in renal tubular epithelial cells

Gonzalez-Michaca, L., Farrugia, G., Croatt, A. J., Alam, J. & Nath, K. A., Feb 2004, In : American Journal of Physiology - Renal Physiology. 286, 2 55-2

Research output: Contribution to journalArticle

Hemin
Heme
Epithelial Cells
Kidney
Heme Oxygenase-1
79 Citations (Scopus)

Mechanisms of aging-induced impairment of endothelium-dependent relaxation: Role of tetrahydrobiopterin

Blackwell, K. A., Sorenson, J. P., Richardson, D. M., Smith, L. A., Suda, O., Nath, K. A. & Katusic, Z. S., Dec 2004, In : American Journal of Physiology - Heart and Circulatory Physiology. 287, 6 56-6

Research output: Contribution to journalArticle

Endothelium
Carotid Arteries
Superoxides
Blood Vessels
Aorta