• 13523 Citations
  • 66 Scopus h-Index
1975 …2020
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Research Output 1983 2020

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151 Citations (Scopus)

Accommodation in ABO-incompatible kidney allografts, a novel mechanism of self-protection against antibody-mediated injury

Park, W. D., Grande, J. P., Ninova, D., Nath, K. A., Platt, J. L., Gloor, J. M. & Stegall, M. D., Aug 2003, In : American Journal of Transplantation. 3, 8, p. 952-960 9 p.

Research output: Contribution to journalArticle

Allografts
Transplants
Kidney
Antibodies
Wounds and Injuries
155 Citations (Scopus)

Acquired resistance to acute oxidative stress. Possible role of heme oxygenase and ferritin

Vogt, B. A., Alam, J., Croatt, A. J., Vercellotti, G. M. & Nath, K. A., 1995, In : Laboratory Investigation. 72, 4, p. 474-483 10 p.

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
Endotoxins
Oxidative Stress
Acute Kidney Injury
Glycerol
42 Citations (Scopus)

Acute cholestatic liver disease protects against glycerol-induced acute renal failure in the rat

Leung, N., Croatt, A. J., Haggard, J. J., Grande, J. P. & Nath, K. A., 2001, In : Kidney International. 60, 3, p. 1047-1057 11 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Glycerol
Liver Diseases
Common Bile Duct
Kidney
2 Citations (Scopus)

Adaptation to the nephrotoxicity of heme proteins

Nath, K. A., 1996, In : Experimental Nephrology. 4, 3, p. 139-143 5 p.

Research output: Contribution to journalArticle

Hemeproteins
Physiological Adaptation
Heme Oxygenase (Decyclizing)
Enzyme Induction
Rhabdomyolysis
19 Citations (Scopus)

Age sensitizes the kidney to heme protein-induced acute kidney injury

Nath, K. A., Grande, J. P., Farrugia, G., Croatt, A. J., Belcher, J. D., Hebbel, R. P., Vercellotti, G. M. & Katusic, Z. S., 2013, In : American Journal of Physiology - Renal Physiology. 304, 3

Research output: Contribution to journalArticle

Hemeproteins
Acute Kidney Injury
Kidney
Hemoglobins
Messenger RNA
31 Citations (Scopus)

AKI: A path forward

Bonventre, J. V., Basile, D., Liu, K. D., McKay, D., Molitoris, B. A., Nath, K. A., Nickolas, T. L., Okusa, M. D., Palevsky, P. M., Schnellmann, R., Rys-Sikora, K., Kimmel, P. L. & Star, R. A., 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1606-1608 3 p.

Research output: Contribution to journalArticle

Research
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Kidney
Kidney Diseases
Animal Models
75 Citations (Scopus)

A major role for carbon monoxide as an endogenous hyperpolarizing factor in the gastrointestinal tract

Farrugia, G., Lei, S., Lin, X., Miller, S. M., Nath, K. A., Ferris, C. D., Levitt, M. & Szurszewski, J. H., Jul 8 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 14, p. 8567-8570 4 p.

Research output: Contribution to journalArticle

Carbon Monoxide
Gastrointestinal Tract
Membrane Potentials
Cell Membrane
Heme Oxygenase (Decyclizing)
1 Citation (Scopus)

A misplaced pulmonary artery catheter.

Pomeroy, C. & Nath, K. A., Mar 1983, In : Annals of Internal Medicine. 98, 3, p. 413 1 p.

Research output: Contribution to journalArticle

Cardiac Catheterization
Thoracic Aorta
Pulmonary Artery
Catheters
23 Citations (Scopus)

Ammonia-complement interaction in the pathogenesis of progressive renal injury

Nath, K. A., Hostetter, M. K. & Hostetter, T. H., 1989, In : Kidney International. 36, SUPPL. 27

Research output: Contribution to journalArticle

Ammonia
Kidney
Nephrons
Wounds and Injuries
Acids
10 Citations (Scopus)

A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade

Solovey, A., Somani, A., Belcher, J. D., Milbauer, L., Vincent, L., Pawlinski, R., Nath, K. A., Kelm, R. J., Mackman, N., O'Sullivan, M. G., Gupta, K., Vercellotti, G. M. & Hebbel, R. P., 2017, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Transgenic Mice
Monocytes
Tumor Necrosis Factor-alpha
Sickle Cell Anemia
Blood Cells
28 Citations (Scopus)

An analysis of the DOCA-salt model of hypertension in HO-1-/- mice and the Gunn rat

Nath, K. A., D'Uscio, L. V., Juncos, J. P., Croatt, A. J., Manriquez, M. C., Pittock, S. T. & Katusic, Z. S., Jul 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 293, 1

Research output: Contribution to journalArticle

Gunn Rats
Desoxycorticosterone Acetate
Heme Oxygenase-1
Salts
Hypertension
16 Citations (Scopus)
Heme Oxygenase-1
Arteriovenous Fistula
Chronic Renal Insufficiency
Up-Regulation
Viral Genes
142 Citations (Scopus)

Angiotensin ii induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitro

Haugen, E. N., Croatt, A. J. & Nath, K. A., 2000, In : Kidney International. 58, 1, p. 144-152 9 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Angiotensins
Oxidants
Angiotensin II
Kidney
18 Citations (Scopus)

Anomalous renal effects of tin protoporphyrin in a murine model of sickle cell disease

Juncos, J. P., Grande, J. P., Murali, N., Croatt, A. J., Juncos, L. A., Hebbel, R. P., Katusic, Z. S. & Nath, K. A., Jul 2006, In : American Journal of Pathology. 169, 1, p. 21-31 11 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Kidney
Heme Oxygenase-1
Wounds and Injuries
Ischemia
97 Citations (Scopus)

Antigen presentation by dendritic cells in renal lymph nodes is linked to systemic and local injury to the kidney

Dong, X., Swaminathan, S., Bachman, L. A., Croatt, A. J., Nath, K. A. & Griffin, M. D., Sep 2005, In : Kidney International. 68, 3, p. 1096-1108 13 p.

Research output: Contribution to journalArticle

Antigen Presentation
Dendritic Cells
Lymph Nodes
Kidney
Wounds and Injuries
23 Citations (Scopus)

A promising approach for treatment of tumor-induced bone diseases: Utilizing bisphosphonate derivatives of nucleoside antimetabolites

Reinholz, M. M., Zinnen, S. P., Dueck, A., Dingli, D. M., Reinholz, G. G., Jonart, L. A., Kitzmann, K. A., Bruzek, A. K., Negron, V., Abdalla, A. K., Arendt, B. K., Croatt, A. J., Sanchez-Perez, L., Sebesta, D. P., Lönnberg, H., Yoneda, T., Nath, K. A., Jelinek, D. F., Russell, S. J., Ingle, J. N. & 4 others, Spelsberg, T. C., Dixon, H. B. F., Karpeisky, A. & Lingle, W. L., Jul 2010, In : Bone. 47, 1, p. 12-22 11 p.

Research output: Contribution to journalArticle

Antimetabolites
Bone Diseases
Diphosphonates
zoledronic acid
Nucleosides
32 Citations (Scopus)

A proposal for standardized grading of chronic changes in native kidney biopsy specimens

Sethi, S. M., D'Agati, V. D., Nast, C. C., Fogo, A. B., De Vriese, A. S., Markowitz, G. S., Glassock, R. J., Fervenza, F. C., Seshan, S. V., Rule, A. D., Racusen, L. C., Radhakrishnan, J., Winearls, C. G., Appel, G. B., Bajema, I. M., Chang, A., Colvin, R. B., Cook, H. T., Hariharan, S., Herrera Hernandez, L. P. & 7 others, Kambham, N., Mengel, M., Nath, K. A., Rennke, H. G., Ronco, P., Rovin, B. H. & Haas, M., Apr 1 2017, In : Kidney International. 91, 4, p. 787-789 3 p.

Research output: Contribution to journalArticle

Arteriosclerosis
Atrophy
Fibrosis
Kidney
Biopsy
55 Citations (Scopus)

A Randomized, Controlled Trial of Rituximab in IgA Nephropathy with Proteinuria and Renal Dysfunction

Lafayette, R. A., Canetta, P. A., Rovin, B. H., Appel, G. B., Novak, J., Nath, K. A., Sethi, S. M., Tumlin, J. A., Mehta, K., Hogan, M. C., Erickson, S., Julian, B. A., Leung, N., Enders, F. T., Brown, R., Knoppova, B., Hall, S. & Fervenza, F. C., Apr 1 2017, In : Journal of the American Society of Nephrology : JASN. 28, 4, p. 1306-1313 8 p.

Research output: Contribution to journalArticle

Proteinuria
Immunoglobulin A
Randomized Controlled Trials
Kidney
Galactose
58 Citations (Scopus)
Systems Biology
Sickle Cell Anemia
Reperfusion Injury
Inflammation
Biological Phenomena
67 Citations (Scopus)
Pyruvic Acid
Hydrogen Peroxide
Cysteine
Metals
Fluorescence
6 Citations (Scopus)

A vector-host system to fingerprint virus tropism.

Hillestad, M. L., Guenzel, A. J., Nath, K. A. & Barry, M. A., Oct 2012, In : Human Gene Therapy. 23, 10, p. 1116-1126 11 p.

Research output: Contribution to journalArticle

Tropism
Dermatoglyphics
Reporter Genes
Luciferases
Viruses
114 Citations (Scopus)

Bcl-xL rescues WEHI 231 B lymphocytes from oxidant-mediated death following diverse apoptotic stimuli

Fang, W., Rivard, J. J., Ganser, J. A., Lebien, T. W., Nath, K. A., Mueller, D. L. & Behrens, T. W., 1995, In : Journal of Immunology. 155, 1, p. 66-75 10 p.

Research output: Contribution to journalArticle

Oxidants
B-Lymphocytes
Apoptosis
Ceramides
Antioxidants
17 Citations (Scopus)

Blockade of CCR2 reduces macrophage influx and development of chronic renal damage in murine renovascular hypertension

Kashyap, S., Warner, G. M., Hartono, S. P., Boyilla, R., Knudsen, B. E., Zubair, A. S., Lien, K., Nath, K. A., Textor, S. C., Lerman, L. O. & Grande, J. P., Mar 1 2016, In : American Journal of Physiology - Renal Physiology. 310, 5, p. F372-F384

Research output: Contribution to journalArticle

Renovascular Hypertension
Chemokine Receptors
Macrophages
Kidney
Atrophy
3 Citations (Scopus)

Cardiovascular phenotype in Smad3 deficient mice with renovascular hypertension

Kashyap, S., Warner, G., Hu, Z., Gao, F., Osman, M., Al Saiegh, Y., Lien, K. R., Nath, K. A. & Grande, J. P., Oct 1 2017, In : PLoS One. 12, 10, e0187062.

Research output: Contribution to journalArticle

Renovascular Hypertension
Surgery
hypertension
Dissection
Phenotype
8 Citations (Scopus)

Ccl2 deficiency protects against chronic renal injury in murine renovascular hypertension

Kashyap, S., Osman, M., Ferguson, C. M., Nath, M. C., Roy, B., Lien, K. R., Nath, K. A., Garovic, V. D., Lerman, L. O. & Grande, J. P., Dec 1 2018, In : Scientific Reports. 8, 1, 8598.

Research output: Contribution to journalArticle

Renovascular Hypertension
Knockout Mice
Kidney
Wounds and Injuries
Renal Artery Obstruction
35 Citations (Scopus)

CD40 inhibits B cell apoptosis by upregulating bcl-x(L) expression and blocking oxidant accumulation

Fang, W., Nath, K. A., Mackey, M. F., Noelle, R. J., Mueller, D. L. & Behrens, T. W., Mar 1997, In : American Journal of Physiology - Cell Physiology. 272, 3 41-3

Research output: Contribution to journalArticle

Oxidants
B-Lymphocytes
Cells
Apoptosis
Immunoglobulin Class Switching
106 Citations (Scopus)

Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis

Inguaggiato, P., Gonzalez-Michaca, L., Croatt, A. J., Haggard, J. J., Alam, J. & Nath, K. A., 2001, In : Kidney International. 60, 6, p. 2181-2191 11 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Up-Regulation
Apoptosis
Cell Cycle
Cycloheximide
4 Citations (Scopus)
Hemeproteins
Glycerol
Arterial Pressure
Nitroprusside
Acetylcholine
38 Citations (Scopus)

Characterization of a model of an arteriovenous fistula in the rat: The effect of L-NAME

Croatt, A. J., Grande, J. P., Hernandez, M. C., Ackerman, A. W., Katusic, Z. S. & Nath, K. A., May 2010, In : American Journal of Pathology. 176, 5, p. 2530-2541 12 p.

Research output: Contribution to journalArticle

NG-Nitroarginine Methyl Ester
Arteriovenous Fistula
Hyperplasia
Renal Dialysis
Nitric Oxide Synthase

CKD Due to a Novel Mitochondrial DNA Mutation: A Case Report

Fervenza, F. C., Gavrilova, R. M., Nasr, S. H., Irazabal Mira, M. & Nath, K. A., Jan 1 2018, (Accepted/In press) In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Kidney Diseases
Mitochondrial DNA
Mutation
Chronic Renal Insufficiency
Mitochondrial Diseases
89 Citations (Scopus)

Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative properties

Schwochau, G. B., Nath, K. A. & Rosenberg, M. E., 1998, In : Kidney International. 53, 6, p. 1647-1653 7 p.

Research output: Contribution to journalArticle

Clusterin
Oxidative Stress
Oxidants
LLC-PK1 Cells
Fibrinogen
23 Citations (Scopus)

Control of Oxidative Stress and Inflammation in Sickle Cell Disease with the Nrf2 Activator Dimethyl Fumarate

Belcher, J. D., Chen, C., Nguyen, J., Zhang, P., Abdulla, F., Nguyen, P., Killeen, T., Xu, P., O'Sullivan, G., Nath, K. A. & Vercellotti, G. M., May 10 2017, In : Antioxidants and Redox Signaling. 26, 14, p. 748-762 15 p.

Research output: Contribution to journalArticle

Oxidative stress
Sickle Cell Anemia
Oxidative Stress
Inflammation
Heme
74 Citations (Scopus)

Deficiency of heme oxygenase-1 impairs renal hemodynamics and exaggerates systemic inflammatory responses to renal ischemia

Tracz, M. J., Juncos, J. P., Croatt, A. J., Ackerman, A. W., Grande, J. P., Knutson, K. L., Kane, G. M., Terzic, A., Griffin, M. D. & Nath, K. A., Nov 2007, In : Kidney International. 72, 9, p. 1073-1080 8 p.

Research output: Contribution to journalArticle

Ischemia
Hemodynamics
Kidney
Interleukin-6
Heme Oxygenase-1
69 Citations (Scopus)

Dendritic cells facilitate accumulation of IL-17 T cells in the kidney following acute renal obstruction

Dong, X., Bachman, L. A., Miller, M. N., Nath, K. A. & Griffin, M. D., Nov 2008, In : Kidney International. 74, 10, p. 1294-1309 16 p.

Research output: Contribution to journalArticle

Interleukin-17
Dendritic Cells
T-Lymphocytes
Kidney
Interferons
19 Citations (Scopus)

De novo focal glomerulosclerosis after kidney transplantation

Woolley, A. C., Rosenberg, M. E., Burke, B. A. & Nath, K. A., 1988, In : The American journal of medicine. 84, 2, p. 310-314 5 p.

Research output: Contribution to journalArticle

Focal Segmental Glomerulosclerosis
Kidney Transplantation
Kidney
Hypertrophy
Allografts
2 Citations (Scopus)

Development of renal atrophy in murine 2 kidney 1 clip hypertension is strain independent

Kashyap, S., Boyilla, R., Zaia, P. J., Ghossan, R., Nath, K. A., Textor, S. C., Lerman, L. O. & Grande, J. P., Aug 1 2016, In : Research in Veterinary Science. 107, p. 171-177 7 p.

Research output: Contribution to journalArticle

atrophy
Surgical Instruments
hypertension
Atrophy
kidneys
65 Citations (Scopus)

Dietary deficiency of antioxidants exacerbates ischemic injury in the rat kidney

Nath, K. A. & Paller, M. S., Dec 1990, In : Kidney International. 38, 6, p. 1109-1117 9 p.

Research output: Contribution to journalArticle

Ischemia
Antioxidants
Kidney
Vitamin E Deficiency
Wounds and Injuries
119 Citations (Scopus)
Dietary Proteins
Kidney
Pressure
Wounds and Injuries
Nephrons
6 Citations (Scopus)

Differentiating scleroderma renal crisis from other causes of thrombotic microangiopathy in a postpartum patient

Abudiab, M. M., Krause, M. L., Fidler, M. E., Nath, K. A. & Norby, S. M., 2013, In : Clinical Nephrology. 80, 4, p. 293-297 5 p.

Research output: Contribution to journalArticle

Thrombotic Microangiopathies
Postpartum Period
Plasma Exchange
Kidney
Mixed Connective Tissue Disease
1 Citation (Scopus)

Disease Progression and End-Stage Renal Disease in Diverse Glomerulopathies

Nath, K. A. & Fervenza, F. C., Jan 1 2018, (Accepted/In press) In : Mayo Clinic Proceedings.

Research output: Contribution to journalArticle

Chronic Kidney Failure
Disease Progression
20 Citations (Scopus)

Early and prominent alterations in hemodynamics, signaling, and gene expression following renal ischemia in sickle cell disease

Juncos, J. P., Grande, J. P., Croatt, A. J., Hebbel, R. P., Vercellotti, G. M., Katusic, Z. S. & Nath, K. A., Apr 2010, In : American Journal of Physiology - Renal Physiology. 298, 4

Research output: Contribution to journalArticle

Sickle Cell Anemia
Ischemia
Hemodynamics
Kidney
Gene Expression
7 Citations (Scopus)

Early Onset Preeclampsia Is Associated With Glycocalyx Degradation and Reduced Microvascular Perfusion

Weissgerber, T. L., Garcia-Valencia, O., Milic, N. M., Codsi, E., Cubro, H., Nath, M. C., White, W. M., Nath, K. A. & Garovic, V. D., Feb 19 2019, In : Journal of the American Heart Association. 8, 4, p. e010647

Research output: Contribution to journalArticle

Glycocalyx
Pre-Eclampsia
Perfusion
Heparan Sulfate Proteoglycans
Gestational Diabetes
18 Citations (Scopus)

Effect of proteinuria on renal interstitium: Effect of products of nitrogen metabolism

Agarwal, A. & Nath, K. A., 1993, In : American Journal of Nephrology. 13, 5, p. 376-384 9 p.

Research output: Contribution to journalArticle

Proteinuria
Nitrogen
Kidney
Wounds and Injuries
Ammonia
46 Citations (Scopus)

Effect of pyruvate on oxidant injury to isolated and cellular DNA

Nath, K. A., Enright, H., Nutter, L., Fischereder, M., Zou, J. N. & Hebbel, R. P., Jan 1994, In : Kidney International. 45, 1, p. 166-176 11 p.

Research output: Contribution to journalArticle

Pyruvic Acid
Oxidants
DNA
Wounds and Injuries
DNA Damage
3 Citations (Scopus)

Effect of γ-L-glutamyl-L-DOPA on phosphate excretion

Sadiq, S., Berndt, T. J., Nath, K. A. & Knox, F. G., Jan 2000, In : Journal of Laboratory and Clinical Medicine. 135, 1, p. 52-56 5 p.

Research output: Contribution to journalArticle

Dopamine
Phosphates
Rats
Prodrugs
Sprague Dawley Rats

Effects of cyclosporine on the renin-angiotensin-aldosterone system and potassium excretion in renal transplant recipients

Bantle, J. P., Nath, K. A., Sutherland, D. E. R., Najarian, J. S. & Ferris, T. F., 1985, In : Archives of Internal Medicine. 145, 3, p. 505-508 4 p.

Research output: Contribution to journalArticle

Renin-Angiotensin System
Cyclosporine
Potassium
Aldosterone
Azathioprine
134 Citations (Scopus)

Effects of Cyclosporine on the Renin-Angiotensin-Aldosterone System and Potassium Excretion in Renal Transplant Recipients

Bantle, J. P., Nath, K. A., Sutherland, D. E. R., Najarian, J. S. & Ferris, T. F., 1985, In : Archives of Internal Medicine. 145, 3, p. 505-508 4 p.

Research output: Contribution to journalArticle

Renin-Angiotensin System
Cyclosporine
Potassium
Aldosterone
Azathioprine
12 Citations (Scopus)

Endogenous superantigens shape response to exogenous superantigens

Rajagopalan, G., Singh, M., Sen, M. M., Murali, N. S., Nath, K. A. & David, C. S., Sep 2005, In : Clinical and Diagnostic Laboratory Immunology. 12, 9, p. 1119-1122 4 p.

Research output: Contribution to journalArticle

Superantigens
T-cells
T-Cell Antigen Receptor
Bearings (structural)
T-Lymphocytes
45 Citations (Scopus)

Endothelial cell heme oxygenase and ferritin induction by heme proteins: a possible mechanism limiting shock damage.

Balla, J., Jacob, H. S., Balla, G., Nath, K. A. & Vercellotti, G. M., 1992, In : Transactions of the Association of American Physicians. 105, p. 1-6 6 p.

Research output: Contribution to journalArticle

Hemeproteins
Heme Oxygenase (Decyclizing)
Methemoglobin
Shock
Heme
112 Citations (Scopus)

Endothelial cell heme oxygenase and ferritin induction in rat lung by hemoglobin in vivo

Balla, J., Nath, K. A., Balla, G., Juckett, M. B., Jacob, H. S. & Vercellotti, G. M., 1995, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 268, 2 12-2

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
Hemoglobins
Endothelial Cells
Methemoglobin
Heme