• 13768 Citations
  • 67 Scopus h-Index
1975 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

Antithrombotic effects of heme-degrading and heme-binding proteins

Nath, K. A., Grande, J. P., Belcher, J. D., Garovic, V. D., Croatt, A. J., Hillestad, M. L., Barry, M. A., Nath, M. C., Regan, R. F. & Vercellotti, G. M., Mar 1 2020, In : American journal of physiology. Heart and circulatory physiology. 318, 3, p. H671-H681

Research output: Contribution to journalArticle

Open Access
2019

Early Onset Preeclampsia Is Associated With Glycocalyx Degradation and Reduced Microvascular Perfusion

Weissgerber, T. L., Garcia-Valencia, O., Milic, N. M., Codsi, E., Cubro, H., Nath, M. C., White, W. M., Nath, K. A. & Garovic, V. D., Feb 19 2019, In : Journal of the American Heart Association. 8, 4, p. e010647

Research output: Contribution to journalArticle

12 Scopus citations

Heme oxygenase-2 protects against ischemic acute kidney injury: influence of age and sex

Nath, K. A., Garovic, V. D., Grande, J. P., Croatt, A. J., Ackerman, A. W., Farrugia, G., Katusic, Z. S., Belcher, J. D. & Vercellotti, G. M., Sep 1 2019, In : American journal of physiology. Renal physiology. 317, 3, p. F695-F704

Research output: Contribution to journalArticle

In Remembrance of Thomas F. Ferris, MD, Former ASN President (1987-1988)

Hostetter, T. & Nath, K. A., Nov 1 2019, In : Journal of the American Society of Nephrology : JASN. 30, 11, p. 2045-2046 2 p.

Research output: Contribution to journalArticle

2018

Ccl2 deficiency protects against chronic renal injury in murine renovascular hypertension

Kashyap, S., Osman, M., Ferguson, C. M., Nath, M. C., Roy, B., Lien, K. R., Nath, K. A., Garovic, V. D., Lerman, L. O. & Grande, J. P., Dec 1 2018, In : Scientific Reports. 8, 1, 8598.

Research output: Contribution to journalArticle

8 Scopus citations

CKD Due to a Novel Mitochondrial DNA Mutation: A Case Report

Fervenza, F. C., Gavrilova, R. M., Nasr, S. H., Irazabal Mira, M. & Nath, K. A., Jan 1 2018, (Accepted/In press) In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Disease Progression and End-Stage Renal Disease in Diverse Glomerulopathies

Nath, K. A. & Fervenza, F. C., Jan 1 2018, (Accepted/In press) In : Mayo Clinic Proceedings.

Research output: Contribution to journalArticle

1 Scopus citations

Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction

Belcher, J. D., Chen, C., Nguyen, J., Abdulla, F., Zhang, P., Nguyen, H., Nguyen, P., Killeen, T., Miescher, S. M., Brinkman, N., Nath, K. A., Steer, C. J. & Vercellotti, G. M., Apr 1 2018, In : PLoS One. 13, 4, e0196455.

Research output: Contribution to journalArticle

22 Scopus citations

Role of TLR4 signaling in the nephrotoxicity of Heme and heme proteins

Nath, K. A., Belcher, J. D., Nath, M. C., Grande, J. P., Croatt, A. J., Ackerman, A. W., Katusic, Z. S. & Vercellotti, G. M., Jan 1 2018, In : American Journal of Physiology - Renal Physiology. 314, 5, p. F906-F914

Research output: Contribution to journalArticle

8 Scopus citations

The murine dialysis fistula model exhibits a senescence phenotype: pathobiological mechanisms and therapeutic potential

Nath, K. A., O'Brien, D. R., Croatt, A. J., Grande, J. P., Ackerman, A. W., Nath, M. C., Yamada, S., Terzic, A., Tchkonia, T., Kirkland, J. L. & Katusic, Z. S., Nov 1 2018, In : American journal of physiology. Renal physiology. 315, 5, p. F1493-F1499

Research output: Contribution to journalArticle

7 Scopus citations
2017

A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade

Solovey, A., Somani, A., Belcher, J. D., Milbauer, L., Vincent, L., Pawlinski, R., Nath, K. A., Kelm, R. J., Mackman, N., O'Sullivan, M. G., Gupta, K., Vercellotti, G. M. & Hebbel, R. P., Nov 2017, In : American journal of hematology. 92, 11, p. 1119-1130 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

A proposal for standardized grading of chronic changes in native kidney biopsy specimens

Sethi, S. M., D'Agati, V. D., Nast, C. C., Fogo, A. B., De Vriese, A. S., Markowitz, G. S., Glassock, R. J., Fervenza, F. C., Seshan, S. V., Rule, A. D., Racusen, L. C., Radhakrishnan, J., Winearls, C. G., Appel, G. B., Bajema, I. M., Chang, A., Colvin, R. B., Cook, H. T., Hariharan, S., Herrera Hernandez, L. P. & 7 others, Kambham, N., Mengel, M., Nath, K. A., Rennke, H. G., Ronco, P., Rovin, B. H. & Haas, M., Apr 1 2017, In : Kidney International. 91, 4, p. 787-789 3 p.

Research output: Contribution to journalArticle

35 Scopus citations

A randomized, controlled trial of rituximab in IgA nephropathy with proteinuria and renal dysfunction

Lafayette, R. A., Canetta, P. A., Rovin, B. H., Appel, G. B., Novak, J., Nath, K. A., Sethi, S., Tumlin, J. A., Mehta, K., Hogan, M., Erickson, S., Julian, B. A., Leung, N., Enders, F. T., Brown, R., Knoppova, B., Hall, S. & Fervenza, F. C., Apr 2017, In : Journal of the American Society of Nephrology. 28, 4, p. 1306-1313 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Cardiovascular phenotype in Smad3 deficient mice with renovascular hypertension

Kashyap, S., Warner, G., Hu, Z., Gao, F., Osman, M., Al Saiegh, Y., Lien, K. R., Nath, K. & Grande, J. P., Oct 2017, In : PloS one. 12, 10, e0187062.

Research output: Contribution to journalArticle

3 Scopus citations

Control of Oxidative Stress and Inflammation in Sickle Cell Disease with the Nrf2 Activator Dimethyl Fumarate

Belcher, J. D., Chen, C., Nguyen, J., Zhang, P., Abdulla, F., Nguyen, P., Killeen, T., Xu, P., O'Sullivan, G., Nath, K. A. & Vercellotti, G. M., May 10 2017, In : Antioxidants and Redox Signaling. 26, 14, p. 748-762 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

Long-term cardiovascular changes following creation of arteriovenous fistula in patients with end stage renal disease

Reddy, Y. N. V., Obokata, M., Dean, P. G., Melenovsky, V., Nath, K. A. & Borlaug, B. A., Jun 21 2017, In : European Heart Journal. 38, 24, p. 1913-1923 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Renal Outcomes in Anticoagulated Patients With Atrial Fibrillation

Yao, X., Tangri, N., Gersh, B. J., Sangaralingham, L. R., Shah, N. D., Nath, K. A. & Noseworthy, P., Nov 28 2017, In : Journal of the American College of Cardiology. 70, 21, p. 2621-2632 12 p.

Research output: Contribution to journalArticle

58 Scopus citations

Urinary extracellular vesicles of podocyte origin and renal injury in preeclampsia

Gilani, S. I., Anderson, U. D., Jayachandran, M., Weissgerber, T. L., Zand, L., White, W. M., Milic, N., Suarez, M. L. G., Vallapureddy, R. R., Nääv, Å., Erlandsson, L., Lieske, J. C., Grande, J. P., Nath, K. A., Hansson, S. R. & Garovic, V. D., Nov 1 2017, In : Journal of the American Society of Nephrology. 28, 11, p. 3363-3372 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
2016
19 Scopus citations

Blockade of CCR2 reduces macrophage influx and development of chronic renal damage in murine renovascular hypertension

Kashyap, S., Warner, G. M., Hartono, S. P., Boyilla, R., Knudsen, B. E., Zubair, A. S., Lien, K., Nath, K. A., Textor, S. C., Lerman, L. O. & Grande, J. P., Mar 1 2016, In : American Journal of Physiology - Renal Physiology. 310, 5, p. F372-F384

Research output: Contribution to journalArticle

17 Scopus citations

Development of renal atrophy in murine 2 kidney 1 clip hypertension is strain independent

Kashyap, S., Boyilla, R., Zaia, P. J., Ghossan, R., Nath, K. A., Textor, S. C., Lerman, L. O. & Grande, J. P., Aug 1 2016, In : Research in Veterinary Science. 107, p. 171-177 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Mayo clinic/renal pathology society consensus report on pathologic classification, diagnosis, and reporting of GN

Sethi, S. M., Haas, M., Markowitz, G. S., D'Agati, V. D., Rennke, H. G., Jennette, J. C., Bajema, I. M., Alpers, C. E., Chang, A., Cornell, L. D., Cosio, F. G., Fogo, A. B., Glassock, R. J., Hariharan, S., Kambham, N., Lager, D. J., Leung, N., Mengel, M., Nath, K. A., Roberts, I. S. & 15 others, Rovin, B. H., Seshan, S. V., Smith, R. J. H., Walker, P. D., Winearls, C. G., Appel, G. B., Alexander, M. P., Cattran, D. C., Casado, C. A., Cook, H. T., De Vriese, A. S., Radhakrishnan, J., Racusen, L. C., Ronco, P. & Fervenza, F. C., May 1 2016, In : Journal of the American Society of Nephrology. 27, 5, p. 1278-1287 10 p.

Research output: Contribution to journalArticle

77 Scopus citations
2015
11 Scopus citations

Kidney disease caused by dysregulation of the complement alternative pathway: An etiologic approach

De Vriese, A. S., Sethi, S. M., Van Praet, J., Nath, K. A. & Fervenza, F. C., Dec 1 2015, In : Journal of the American Society of Nephrology. 26, 12, p. 2917-2929 13 p.

Research output: Contribution to journalArticle

42 Scopus citations

Models of human AKI: Resemblance, reproducibility, and return on investment

Nath, K. A., Dec 1 2015, In : Journal of the American Society of Nephrology. 26, 12, p. 2891-2893 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Modulation of Mitochondrial Complex I Activity Averts Cognitive Decline in Multiple Animal Models of Familial Alzheimer's Disease

Zhang, L., Zhang, S., Maezawa, I., Trushin, S., Minhas, P., Pinto, M., Jin, L. W., Prasain, K., Nguyen, T. D. T., Yamazaki, Y., Kanekiyo, T., Bu, G. D., Gateno, B., Chang, K. O., Nath, K. A., Nemutlu, E., Dzeja, P. P., Pang, Y-P., Hua, D. H. & Trushina, E. D., Apr 1 2015, In : EBioMedicine. 2, 4, p. 294-305 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Sickle cell disease: Renal manifestations and mechanisms

Nath, K. A. & Hebbel, R. P., Mar 27 2015, In : Nature Reviews Nephrology. 11, 3, p. 161-171 11 p.

Research output: Contribution to journalArticle

116 Scopus citations
2014

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

Belcher, J. D., Chen, C., Nguyen, J., Milbauer, L., Abdulla, F., Alayash, A. I., Smith, A., Nath, K. A., Hebbel, R. P. & Vercellotti, G. M., Jan 16 2014, In : Blood. 123, 3, p. 377-390 14 p.

Research output: Contribution to journalArticle

267 Scopus citations

H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice

Vercellotti, G. M., Khan, F. B., Nguyen, J., Chen, C., Bruzzone, C. M., Bechtel, H., Brown, G., Nath, K. A., Steer, C. J., Hebbel, R. P. & Belcher, J. D., Jan 1 2014, In : Frontiers in Pharmacology. 5 APR, Article 79.

Research output: Contribution to journalArticle

22 Scopus citations
2013

Age sensitizes the kidney to heme protein-induced acute kidney injury

Nath, K. A., Grande, J. P., Farrugia, G., Croatt, A. J., Belcher, J. D., Hebbel, R. P., Vercellotti, G. M. & Katusic, Z. S., Feb 8 2013, In : American Journal of Physiology - Renal Physiology. 304, 3, p. F317-F325

Research output: Contribution to journalArticle

19 Scopus citations

AKI: A path forward

Bonventre, J. V., Basile, D., Liu, K. D., McKay, D., Molitoris, B. A., Nath, K. A., Nickolas, T. L., Okusa, M. D., Palevsky, P. M., Schnellmann, R., Rys-Sikora, K., Kimmel, P. L. & Star, R. A., Sep 16 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1606-1608 3 p.

Research output: Contribution to journalArticle

31 Scopus citations

Differentiating scleroderma renal crisis from other causes of thrombotic microangiopathy in a postpartum patient

Abudiab, M. M., Krause, M. L., Fidler, M. E., Nath, K. A. & Norby, S. M., Oct 8 2013, In : Clinical nephrology. 80, 4, p. 293-297 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Functioning of an arteriovenous fistula requires heme oxygenase

Kang, L., Grande, J. P., Farrugia, G., Croatt, A. J., Katusic, Z. S. & Nath, K. A., May 8 2013, In : American Journal of Physiology - Renal Physiology. 305, 4, p. F545F-F552

Research output: Contribution to journalArticle

12 Scopus citations

Inhibition of p38 MAPK attenuates renal atrophy and fibrosis in a murine renal artery stenosis model

Wang, D., Warner, G. M., Yin, P., Knudsen, B. E., Cheng, J., Butters, K. A., Lien, K. R., Gray, C. E., Garovic, V. D., Lerman, L. O., Textor, S. C., Nath, K. A., Simari, R. D. & Grande, J. P., Jun 10 2013, In : American Journal of Physiology - Renal Physiology. 304, 7, p. F938-F947

Research output: Contribution to journalArticle

35 Scopus citations

Redox signaling is an early event in the pathogenesis of renovascular hypertension

Hartono, S. P., Knudsen, B. E., Zubair, A. S., Nath, K. A., Textor, S. J., Lerman, L. O. & Grande, J. P., Sep 10 2013, In : International journal of molecular sciences. 14, 9, p. 18640-18656 17 p.

Research output: Contribution to journalArticle

15 Scopus citations
2012

A Vector–Host System to Fingerprint Virus Tropism

Hillestad, M. L., Guenzel, A. J., Nath, K. A. & Barry, M. A., Oct 1 2012, In : Human gene therapy. 23, 10, p. 1116-1126 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Experimental mild renal insufficiency mediates early cardiac apoptosis, fibrosis, and diastolic dysfunction: A kidney-heart connection

Martin, F. L., McKie, P. M., Cataliotti, A., Jeson Sangaralingham, S., Korinek, J., Huntley, B. K., Oehler, E. A., Harders, G. E., Ichiki, T., Mangiafico, S., Nath, K. A., Redfield, M. M., Chen, H. H. & Burnett, J. C., Jan 1 2012, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 302, 2, p. R292-R299

Research output: Contribution to journalArticle

52 Scopus citations

Genetic deficiency of Smad3 protects the kidneys from atrophy and interstitial fibrosis in 2K1C hypertension

Warner, G. M., Cheng, J., Knudsen, B. E., Gray, C. E., Deibel, A., Juskewitch, J. E., Lerman, L. O., Textor, S. C., Nath, K. A. & Grande, J. P., Jun 1 2012, In : American Journal of Physiology - Renal Physiology. 302, 11, p. F1455-F1464

Research output: Contribution to journalArticle

40 Scopus citations

Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice

Cummins, N. W., Weaver, E. A., May, S. M., Croatt, A. J., Foreman, O., Kennedy, R. B., Poland, G. A., Barry, M. A., Nath, K. A. & Badley, A. D., Jul 1 2012, In : FASEB Journal. 26, 7, p. 2911-2918 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Increased production of superoxide anion contributes to dysfunction of the arteriovenous fistula

Tsapenko, M. V., d'Uscio, L. V., Grande, J. P., Croatt, A. J., Hernandez, M. C., Ackerman, A. W., Katusic, Z. S. & Nath, K. A., Dec 15 2012, In : American Journal of Physiology - Renal Physiology. 303, 12, p. F1601-F1607

Research output: Contribution to journalArticle

18 Scopus citations

Interleukin-1 accounts for intrarenal Th17 cell activation during ureteral obstruction

Pindjakova, J., Hanley, S. A., Duffy, M. M., Sutton, C. E., Weidhofer, G. A., Miller, M. N., Nath, K. A., Mills, K. H. G., Ceredig, R. & Griffin, M. D., Feb 2 2012, In : Kidney international. 81, 4, p. 379-390 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

LPS-induced murine systemic inflammation is driven by parenchymal cell activation and exclusively predicted by early MCP-1 plasma levels

Juskewitch, J. E., Knudsen, B. E., Platt, J. L., Nath, K. A., Knutson, K. L., Brunn, G. J. & Grande, J. P., Jan 1 2012, In : American Journal of Pathology. 180, 1, p. 32-40 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

The modulatory role of heme oxygenase on subpressor angiotensin II-induced hypertension and renal injury

Chandrashekar, K., Lopez-Ruiz, A., Juncos, R., Nath, K., Stec, D. E., Vera, T., Liu, R. & Juncos, L. A., Nov 7 2012, In : International Journal of Hypertension. 2012, 392890.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Genetic deficiency of Smad3 protects against murine ischemic acute kidney injury

Nath, K. A., Croatt, A. J., Warner, G. M. & Grande, J. P., Aug 1 2011, In : American Journal of Physiology - Renal Physiology. 301, 2, p. F436-F442

Research output: Contribution to journalArticle

27 Scopus citations

MCP-1 contributes to arteriovenous fistula failure

Juncos, J. P., Grande, J. P., Kang, L., Ackerman, A. W., Croatt, A. J., Katusic, Z. S. & Nath, K. A., Jan 1 2011, In : Journal of the American Society of Nephrology. 22, 1, p. 43-48 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

n-3 Fatty acids block TNF-α -stimulated MCP-1 expression in rat mesangial cells

Diaz Encarnacion, M. M., Warner, G. M., Cheng, J., Gray, C. E., Nath, K. A. & Grande, J. P., May 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 5, p. 1142-1151 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Outcomes of arteriovenous fistula creation after the fistula first initiative

Schinstock, C. A., Albright, R. C., Williams, A. W., Dillon, J. J., Bergstralh, E. J., Jenson, B. M., McCarthy, J. T. & Nath, K. A., Aug 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 8, p. 1996-2002 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

Regional and systemic hemodynamic responses following the creation of a murine arteriovenous fistula

Kang, L., Yamada, S., Hernandez, M. C., Croatt, A. J., Grande, J. P., Juncos, J. P., Vercellotti, G. M., Hebbel, R. P., Katusic, Z. S., Terzic, A. & Nath, K. A., Oct 1 2011, In : American Journal of Physiology - Renal Physiology. 301, 4, p. F845-F851

Research output: Contribution to journalArticle

16 Scopus citations

Selective enhancement of contractions to α1-adrenergic receptor activation in the aorta of mice with sickle cell disease

Juncos, R., Juncos, L., Hebbel, R. P., Vercellotti, G. M., Katusic, Z. S. & Nath, K. A., Feb 1 2011, In : Journal of Cardiovascular Pharmacology. 57, 2, p. 263-266 4 p.

Research output: Contribution to journalArticle

5 Scopus citations
2010

A promising approach for treatment of tumor-induced bone diseases: Utilizing bisphosphonate derivatives of nucleoside antimetabolites

Reinholz, M. M., Zinnen, S. P., Dueck, A. C., Dingli, D., Reinholz, G. G., Jonart, L. A., Kitzmann, K. A., Bruzek, A. K., Negron, V., Abdalla, A. K., Arendt, B. K., Croatt, A. J., Sanchez-Perez, L., Sebesta, D. P., Lönnberg, H., Yoneda, T., Nath, K. A., Jelinek, D. F., Russell, S. J., Ingle, J. N. & 4 others, Spelsberg, T. C., Dixon, H. B. F., Karpeisky, A. & Lingle, W. L., Jul 1 2010, In : Bone. 47, 1, p. 12-22 11 p.

Research output: Contribution to journalArticle

23 Scopus citations