• 14067 Citations
  • 67 Scopus h-Index
1983 …2020

Research output per year

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Research Output

2003

Low-Dose Angiotensin II Enhances Pressor Responses Without Causing Sustained Hypertension

Pelaez, L. I., Manriquez, M. C., Nath, K. A., Romero, J. C. & Juncos, L. A., Oct 2003, In : Hypertension. 42, 4, p. 798-801 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Nitric Oxide Synthase Gene Transfer as a Tool to Study Biology of Endothelial Cells

Katusic, Z. S., Caplice, N. M. & Nath, K. A., Nov 2003, In : Arteriosclerosis, thrombosis, and vascular biology. 23, 11, p. 1990-1994 5 p.

Research output: Contribution to journalShort survey

4 Scopus citations

Vitamin E prevents renal dysfunction induced by experimental chronic bile duct ligation

Ortiz, M. C., Manriquez, M. C., Nath, K. A., Lager, D. J., Romero, J. C. & Juncos, L. A., Sep 1 2003, In : Kidney international. 64, 3, p. 950-961 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
2002

TGF-β1 is an autocrine mediator of renal tubular epithelial cell growth and collagen IV production

Grande, J. P., Warner, G. M., Walker, H. J., Yusufi, A. N. K., Cheng, J., Gray, C. E., Kopp, J. B. & Nath, K. A., Mar 2002, In : Experimental Biology and Medicine. 227, 3, p. 171-181 11 p.

Research output: Contribution to journalArticle

31 Scopus citations
2001

Acute cholestatic liver disease protects against glycerol-induced acute renal failure in the rat

Leung, N., Croatt, A. J., Haggard, J. J., Grande, J. P. & Nath, K. A., Jan 1 2001, In : Kidney international. 60, 3, p. 1047-1057 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis

Inguaggiato, P., Gonzalez-Michaca, L., Croatt, A. J., Haggard, J. J., Alam, J. & Nath, K. A., Jan 1 2001, In : Kidney international. 60, 6, p. 2181-2191 11 p.

Research output: Contribution to journalArticle

108 Scopus citations

Heme protein-induced chronic renal inflammation: Suppressive effect of induced heme oxygenase-1

Nath, K. A., Vercellotti, G. M., Grande, J. P., Miyoshi, H., Paya, C. V., Manivel, J. C., Haggard, J. J., Croatt, A. J., Payne, W. D. & Alam, J., Jan 2001, In : Kidney international. 59, 1, p. 106-117 12 p.

Research output: Contribution to journalArticle

176 Scopus citations

Increased oxidative stress in experimental renovascular hypertension

Lerman, L. O., Nath, K. A., Rodriguez-Porcel, M., Krier, J. D., Schwartz, R. S., Napoli, C. & Romero, J. C., 2001, In : Hypertension. 37, 2 II, p. 541-546 6 p.

Research output: Contribution to journalArticle

Open Access
231 Scopus citations

Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease

Nath, K. A., Grande, J. P., Haggard, J. J., Croatt, A. J., Katusic, Z. S., Solovey, A. & Hebbel, R. P., 2001, In : American Journal of Pathology. 158, 3, p. 893-903 11 p.

Research output: Contribution to journalArticle

139 Scopus citations

Protective effect of heme oxygenase-1 gene transfer against oxyhemoglobin-induced endothelial dysfunction

Eguchi, D., Weiler, D., Alam, J., Nath, K. & Katusic, Z. S., 2001, In : Journal of Cerebral Blood Flow and Metabolism. 21, 10, p. 1215-1222 8 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Simvastatin preserves coronary endothelial function in hypercholesterolemia in the absence of lipid lowering

Wilson, S. H., Simari, R. D., Best, P. J. M., Peterson, T. E., Lerman, L. O., Aviram, M., Nath, K. A., Holmes, D. R. & Lerman, A., Jan 1 2001, In : Arteriosclerosis, thrombosis, and vascular biology. 21, 1, p. 122-128 7 p.

Research output: Contribution to journalArticle

Open Access
158 Scopus citations
2000

Angiotensin ii induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitro

Haugen, E. N., Croatt, A. J. & Nath, K. A., Jan 1 2000, In : Kidney international. 58, 1, p. 144-152 9 p.

Research output: Contribution to journalArticle

143 Scopus citations

Effect of γ-L-glutamyl-L-DOPA on phosphate excretion

Sadiq, S., Berndt, T. J., Nath, K. A. & Knox, F. G., Jan 1 2000, In : Journal of Laboratory and Clinical Medicine. 135, 1, p. 52-56 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease

Nath, K. A., Shah, V., Haggard, J. J., Croatt, A. J., Smith, L. A., Hebbel, R. P. & Katusic, Z. S., 2000, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 279, 6 48-6, p. R1949-R1955

Research output: Contribution to journalArticle

74 Scopus citations

Mechanisms underlying induction of heme oxygenase-1 by nitric oxide in renal tubular epithelial cells

Liang, M., Croatt, A. J. & Nath, K. A., 2000, In : American Journal of Physiology - Renal Physiology. 279, 4 48-4, p. F728-F735

Research output: Contribution to journalArticle

43 Scopus citations

Reactive oxygen species and acute renal failure

Nath, K. A. & Norby, S. M., Dec 1 2000, In : American Journal of Medicine. 109, 8, p. 665-678 14 p.

Research output: Contribution to journalComment/debate

317 Scopus citations

Renal response to repetitive exposure to heme proteins: Chronic injury induced by an acute insult

Nath, K. A., Croatt, A. J., Haggard, J. J. & Grande, J. P., Jan 1 2000, In : Kidney international. 57, 6, p. 2423-2433 11 p.

Research output: Contribution to journalArticle

100 Scopus citations

Role of adenosine in contrast media-induced acute renal failure in diabetes mellitus

Pflueger, A., Larson, T. S., Nath, K. A., King, B. F., Gross, J. M. & Knox, F. G., Jan 1 2000, In : Mayo Clinic proceedings. 75, 12, p. 1275-1283 9 p.

Research output: Contribution to journalReview article

Open Access
78 Scopus citations

The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo

Nath, K. A., Haggard, J. J., Croatt, A. J., Grande, J. P., Poss, K. D. & Alam, J., 2000, In : American Journal of Pathology. 156, 5, p. 1527-1535 9 p.

Research output: Contribution to journalArticle

221 Scopus citations
1999

Characterization of acute reversible systemic hypertension in a model of heme protein-induced renal injury

Warden, D. H., Croatt, A. J., Katusic, Z. S. & Nath, K. A., Jul 1999, In : American Journal of Physiology - Renal Physiology. 277, 1 46-1, p. F58-F65

Research output: Contribution to journalArticle

4 Scopus citations
Open Access
45 Scopus citations

The involvement of oxidative stress in the progression of renal injury

Haugen, E. & Nath, K. A., Sep 3 1999, In : Blood Purification. 17, 2-3, p. 58-65 8 p.

Research output: Contribution to journalArticle

111 Scopus citations
1998

Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative properties

Schwochau, G. B., Nath, K. A. & Rosenberg, M. E., Jan 1 1998, In : Kidney international. 53, 6, p. 1647-1653 7 p.

Research output: Contribution to journalArticle

92 Scopus citations

Heme oxygenase: Protective gene or trojan horse

Platt, J. L. & Nath, K. A., Dec 16 1998, In : Nature Medicine. 4, 12, p. 1364-1365 2 p.

Research output: Contribution to journalShort survey

205 Scopus citations

Intracellular targets in heme protein-induced renal injury

Nath, K. A., Grande, J. P., Croatt, A. J., Likely, S., Hebbel, R. P. & Enright, H., Jan 1 1998, In : Kidney international. 53, 1, p. 100-111 12 p.

Research output: Contribution to journalArticle

88 Scopus citations

Redox regulation of renal DNA synthesis, transforming growth factor-β1 and collagen gene expression

Nath, K. A., Grande, J., Croatt, A., Haugen, J., Kim, Y. & Rosenberg, M. E., Jan 1 1998, In : Kidney international. 53, 2, p. 367-381 15 p.

Research output: Contribution to journalArticle

96 Scopus citations

The tubulointerstitium in progressive renal disease

Nath, K. A., Jan 1 1998, In : Kidney international. 54, 3, p. 992-994 3 p.

Research output: Contribution to journalEditorial

148 Scopus citations
1997

CD40 inhibits B cell apoptosis by upregulating bcl-x(L) expression and blocking oxidant accumulation

Fang, W., Nath, K. A., Mackey, M. F., Noelle, R. J., Mueller, D. L. & Behrens, T. W., Mar 1997, In : American Journal of Physiology - Cell Physiology. 272, 3 41-3, p. C950-C956

Research output: Contribution to journalArticle

35 Scopus citations

Hydrogen peroxide downregulates IL-1-driven mesangial iNOS activity: Implications for glomerulonephritis

Jaimes, E. A., Nath, K. A. & Raij, L., Dec 1 1997, In : American Journal of Physiology. 272, 6 PART 2, p. F729-F735

Research output: Contribution to journalArticle

Hydrogen peroxide downregulates IL-1-driven mesangial iNOS activity: Implications for glomerulonephritis

Jaimes, E. A., Nath, K. A. & Raij, L., 1997, In : American Journal of Physiology - Renal Physiology. 272, 6 41-6, p. F721-F728

Research output: Contribution to journalArticle

21 Scopus citations

Temporal Induction of Clusterin in Cisplatin Nephrotoxicity

Silkensen, J. R., Agarwal, A., Nath, K. A., Manivel, J. C. & Rosenberg, M. E., Feb 1 1997, In : Journal of the American Society of Nephrology. 8, 2, p. 302-305 4 p.

Research output: Contribution to journalArticle

29 Scopus citations
1996

Adaptation to the nephrotoxicity of heme proteins

Nath, K. A., May 21 1996, In : Experimental Nephrology. 4, 3, p. 139-143 5 p.

Research output: Contribution to journalReview article

2 Scopus citations

Endothelial processes contribute to vasoconstriction in acute renal failure (arf)

Warden, D. H. & Nath, K. A., Jan 1 1996, In : Journal of Investigative Medicine. 44, 3, p. 304a

Research output: Contribution to journalArticle

Gas-generating systems in acute renal allograft rejection in the rat: Co-induction of heme oxygenase and nitric oxide synthase

Agarwal, A., Kim, Y., Matas, A. J., Alam, J. & Nath, K. A., Jan 15 1996, In : Transplantation. 61, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

Glomerular inflammation induces resistance to tubular injury in the rat. A novel form of acquired, heme oxygenase-dependent resistance to renal injury

Vogt, B. A., Shanley, T. P., Croatt, A., Alam, J., Johnson, K. J. & Nath, K. A., Nov 1 1996, In : Journal of Clinical Investigation. 98, 9, p. 2139-2145 7 p.

Research output: Contribution to journalArticle

Open Access
108 Scopus citations

Heme arginate and the endothelium: mechanism for its safety in porphyria

Balla, J., Balla, G., Kakuk, G., Nath, K. A., Jacob, H. S. & Vercellolti, G. M., Jan 1 1996, In : Journal of Investigative Medicine. 44, 3, p. 214a

Research output: Contribution to journalArticle

Renal oxidant injury and oxidant response induced by mercury

Nath, K. A., Croatt, A. J., Likely, S., Behrens, T. W. & Warden, D., Jan 1 1996, In : Kidney international. 50, 3, p. 1032-1043 12 p.

Research output: Contribution to journalArticle

Open Access
111 Scopus citations

Renal tubular epithelial cells mimic endothelial cells upon exposure to oxidized LDL

Agarwal, A., Balla, J., Balla, G., Croatt, A. J., Vercellotti, G. M. & Nath, K. A., 1996, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 271, 4 40-4, p. F814-F823

Research output: Contribution to journalArticle

76 Scopus citations

Reshaping the interstitium by platelet-derived growth factor. Implications for progressive renal disease.

Nath, K. A., Apr 1996, In : The American journal of pathology. 148, 4, p. 1031-1036 6 p.

Research output: Contribution to journalReview article

9 Scopus citations
1995

Acquired resistance to acute oxidative stress. Possible role of heme oxygenase and ferritin

Vogt, B. A., Alam, J., Croatt, A. J., Vercellotti, G. M. & Nath, K. A., Jan 1 1995, In : Laboratory Investigation. 72, 4, p. 474-483 10 p.

Research output: Contribution to journalArticle

159 Scopus citations

Bcl-x(L) rescues WEHI 231 B lymphocytes from oxidant-mediated death following diverse apoptotic stimuli

Fang, W., Rivard, J. J., Ganser, J. A., LeBien, T. W., Nath, K. A., Mueller, D. L. & Behrens, T. W., 1995, In : Journal of Immunology. 155, 1, p. 66-75 10 p.

Research output: Contribution to journalArticle

114 Scopus citations

Endothelial cell heme oxygenase and ferritin induction in rat lung by hemoglobin in vivo

Balla, J., Nath, K. A., Balla, G., Juckett, M. B., Jacob, H. S. & Vercellotti, G. M., 1995, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 268, 2 12-2, p. L321-L327

Research output: Contribution to journalArticle

112 Scopus citations

Heme protein-mediated renal injury: A protective role for 21-aminosteroids in vitro and in vivo

Nath, K. A., Balla, J., Croatt, A. J. & Vercellotti, G. M., Feb 1995, In : Kidney international. 47, 2, p. 592-602 11 p.

Research output: Contribution to journalArticle

Open Access
84 Scopus citations

Induction of heme oxygenase in toxic renal injury: A protective role in cisplatin nephrotoxicity in the rat

Agarwal, A., Balla, J., Alam, J., Croatt, A. J. & Nath, K. A., Oct 1995, In : Kidney international. 48, 4, p. 1298-1307 10 p.

Research output: Contribution to journalArticle

Open Access
208 Scopus citations

Recurrent hemolytic uremic syndrome in an adult renal allograft recipient: Current concepts and management

Agarwal, A., Mauer, S. M., Matas, A. J. & Nath, K. A., Oct 1 1995, In : Journal of the American Society of Nephrology. 6, 4, p. 1160-1169 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

α-Ketoacids scavenge H2O2 in vitro and in vivo and reduce menadione- induced DNA injury and cytotoxicity

Nath, K. A., Ngo, E. O., Hebbel, R. P., Croatt, A. J., Zhou, B. & Nutter, L. M., 1995, In : American Journal of Physiology - Cell Physiology. 268, 1 37-1, p. C227-C236

Research output: Contribution to journalArticle

123 Scopus citations
1994

Effect of pyruvate on oxidant injury to isolated and cellular DNA

Nath, K. A., Enright, H., Nutter, L., Fischereder, M., Zou, J. N. & Hebbel, R. P., Jan 1994, In : Kidney international. 45, 1, p. 166-176 11 p.

Research output: Contribution to journalArticle

Open Access
47 Scopus citations

Heme and the vasculature: An oxidative hazard that induces antioxidant defenses in the endothelium

Vercellotti, G. M., Balla, G., Balla, J., Nath, K., Eaton, J. W. & Jacob, H. S., Jan 1994, In : Artificial Cells, Blood Substitutes, and Biotechnology. 22, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Induction of clusterin in acute and chronic oxidative renal disease in the rat and its dissociation from cell injury

Nath, K. A., Dvergsten, J., Correa-Rotter, R., Hostetter, T. H., Manivel, J. C. & Rosenberg, M. E., Jan 1 1994, In : Laboratory Investigation. 71, 2, p. 209-218 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Internucleosomal cleavage of DNA as the sole criterion for apoptosis may be artifactual

Enright, H., Hebbel, R. P. & Nath, K. A., Jul 1994, In : The Journal of Laboratory and Clinical Medicine. 124, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

51 Scopus citations