Karen Elaine Hedin, PhD

  • 1411 Citations
  • 19 Scopus h-Index
1993 …2019

Research output per year

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Projects

Targeting osteoblasts to inhibit AML

Hedin, K. E.

4/23/153/31/17

Project: Research project

CXCR4 CHEMOKINE RECEPTOR REGULATION OF ERK MAP KINASE

Hedin, K. E.

9/30/992/29/16

Project: Research project

Research Output

  • 1411 Citations
  • 19 Scopus h-Index
  • 28 Article
  • 1 Chapter
  • 1 Short survey
  • 1 Review article

GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts

Sterner, R. M., Sakemura, R., Cox, M. J., Yang, N., Khadka, R. H., Forsman, C. L., Hansen, M. J., Jin, F., Ayasoufi, K., Hefazi, M., Schick, K. J., Walters, D. K., Ahmed, O., Chappell, D., Sahmoud, T., Durrant, C., Nevala, W. K., Patnaik, M. M., Pease, L. R., Hedin, K. E. & 3 others, Kay, N. E., Johnson, A. J. & Kenderian, S. S., Feb 14 2019, In : Blood. 133, 7, p. 697-709 13 p.

Research output: Contribution to journalArticle

  • 41 Scopus citations

    GRK2 mediates TCR-induced transactivation of CXCR4 and TCR–CXCR4 complex formation that drives PI3K/PREX1 signaling and T cell cytokine secretion

    Dinkel, B. A., Kremer, K. N., Rollins, M. R., Medlyn, M. J. & Hedin, K. E., Jan 1 2018, In : Journal of Biological Chemistry. 293, 36, p. 14022-14039 18 p.

    Research output: Contribution to journalArticle

  • 9 Scopus citations

    Tissue-nonspecific alkaline phosphatase is required for MC3T3 osteoblast-mediated protection of acute myeloid leukemia cells from apoptosis

    Sterner, R. M., Kremer, K. N., Dudakovic, A., Westendorf, J. J., van Wijnen, A. J. & Hedin, K. E., Aug 1 2018, In : Journal of Immunology. 201, 3, p. 1086-1096 11 p.

    Research output: Contribution to journalArticle

  • 5 Scopus citations

    Histone deacetylase inhibitors reduce differentiating osteoblastmediated protection of acute myeloid leukemia cells from cytarabine

    Sterner, R. M., Kremer, K. N., Al-Kali, A., Patnaik, M. M., Gangat, N., Litzow, M. R., Kaufmann, S. H., Westendorf, J. J., van Wijnen, A. J. & Hedin, K. E., Nov 1 2017, In : Oncotarget. 8, 55, p. 94569-94579 11 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    TCR-CXCR4 signaling stabilizes cytokine mRNA transcripts via a PREX1-Rac1 pathway: Implications for CTCL

    Kremer, K. N., Dinkel, B. A., Sterner, R. M., Osborne, D. G., Jevremovic, D. & Hedin, K. E., Aug 24 2017, In : Blood. 130, 8, p. 982-994 13 p.

    Research output: Contribution to journalArticle

  • 8 Scopus citations