• 20708 Citations
  • 80 Scopus h-Index
1974 …2020

Research output per year

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Research Output

Article

Skeletal muscle myosin heavy-chain synthesis rate in healthy humans

Balagopal, P., Ljungqvist, O. & Nair, K. S., Jan 1997, In : American Journal of Physiology - Endocrinology and Metabolism. 272, 1 35-1, p. E45-E50

Research output: Contribution to journalArticle

62 Scopus citations

Sparing of muscle mass and function by passive loading in an experimental intensive care unit model

Renaud, G., Llano-Diez, M., Ravara, B., Gorza, L., Feng, H. Z., Jin, J. P., Cacciani, N., Gustafson, A. M., Ochala, J., Corpeno, R., Li, M., Hedström, Y., Ford, G. C., Nair, K. S. & Larsson, L., Mar 2013, In : Journal of Physiology. 591, 5, p. 1385-1402 18 p.

Research output: Contribution to journalArticle

27 Scopus citations

Splanchnic release of ghrelin in humans

Møller, N., Nygren, J., Hansen, T. K., Ørskov, H., Frystyk, J. & Nair, K. S., Feb 1 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 2, p. 850-852 3 p.

Research output: Contribution to journalArticle

28 Scopus citations

Statement of principle

Cefalu, W. T., Nair, K. S., Seaquist, E. R., Zierath, J., Boulton, A. J. M., LeRoith, D., Harrell, R. M., Grunberger, G., Wartofsky, L., Gore, A. C., Wierman, M. E., Hammes, S. R., Lange, C. A. & Santen, R. J., Feb 1 2015, In : Hormones and Cancer. 6, 1, p. 1 1 p.

Research output: Contribution to journalArticle

Stimulation of protein turnover by carbohydrate overfeeding in men

Welle, S., Matthews, D. E., Campbell, R. G. & Nair, K. S., 1989, In : American Journal of Physiology - Endocrinology and Metabolism. 257, 3, p. 20/3

Research output: Contribution to journalArticle

26 Scopus citations

Surgery-induced insulin resistance in human patients: Relation to glucose transport and utilization

Thorell, A., Nygren, J., Hirshman, M. F., Hayashi, T., Nair, K. S., Horton, E. S., Goodyear, L. J. & Ljungqvist, O., Apr 1999, In : American Journal of Physiology - Endocrinology and Metabolism. 276, 4 39-4, p. E754-E761

Research output: Contribution to journalArticle

74 Scopus citations

Synthesis rate of muscle proteins, muscle functions, and amino acid kinetics in type 2 diabetes

Halvatsiotis, P., Short, K. R., Bigelow, M. & Sreekumaran Nair, K., 2002, In : Diabetes. 51, 8, p. 2395-2404 10 p.

Research output: Contribution to journalArticle

Open Access
115 Scopus citations

T3 increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and -3

Short, K. R., Nygren, J., Barazzoni, R., James Levine, A. & Nair, K. S., May 2001, In : American Journal of Physiology - Endocrinology and Metabolism. 280, 5 43-5, p. E761-E769

Research output: Contribution to journalArticle

82 Scopus citations

TFAM enhances fat oxidation and attenuates high-fat diet-induced insulin resistance in skeletal muscle

Koh, J. H., Johnson, M. L., Dasari, S., LeBrasseur, N. K., Vuckovic, I., Henderson, G. C., Cooper, S. A., Manjunatha, S., Ruegsegger, G. N., Shulman, G. I., Lanza, I. R. & Nair, K. S., Aug 1 2019, In : Diabetes. 68, 8, p. 1552-1564 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

The 2010 ESPEN Sir David Cuthbertson Lecture: New and old proteins: Clinical implications

McCoy, R. G. & Nair, K. S., Oct 2013, In : Clinical Nutrition. 32, 5, p. 728-736 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

The decisive role of free fatty acids for protein conservation during fasting in humans with and without growth hormone

Nørrelund, H., Nair, K. S., Nielsen, S., Frystyk, J., Ivarsen, P., Jørgensen, J. O. L., Christiansen, J. S. & Møller, N., Sep 1 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 9, p. 4371-4378 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

The effect of branched chain amino acids on skeletal muscle mitochondrial function in young and elderly adults

Tatpati, L. L., Irving, B. A., Tom, A., Bigelow, M. L., Klaus, K., Short, K. R. & Nair, K. S., Feb 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 894-902 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

The effect of high glucocorticoid administration and food restriction on rodent skeletal muscle mitochondrial function and protein metabolism

You, Y. N., Short, K. R., Jourdan, M., Klaus, K. A., Walrand, S. & Nair, K. S., Apr 20 2009, In : PloS one. 4, 4, e5283.

Research output: Contribution to journalArticle

15 Scopus citations

The effect of insulin on human small intestinal mucosal protein synthesis

Charlton, M., Ahlman, B. & Nair, K. S., 2000, In : Gastroenterology. 118, 2, p. 299-306 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

The effects of growth hormone and/or testosterone on whole body protein kinetics and skeletal muscle gene expression in healthy elderly men: A randomized controlled trial

Giannoulis, M. G., Jackson, N., Shojaee-Moradie, F., Nair, K. S., Sonksen, P. H., Martin, F. C. & Umpleby, A. M., Aug 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 8, p. 3066-3074 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

The effects of non-insulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues

Turk, D., Alzaid, A., Dinneen, S., Nair, K. S. & Rizza, R., Feb 1995, In : Journal of Clinical Investigation. 95, 2, p. 755-762 8 p.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

The impact of overt and subclinical hyperthyroidism on skeletal muscle

Brennan, M. D., Powell, C., Kaufman, K. R., Sun, P. C., Bahn, R. S. & Nair, K. S., Apr 1 2006, In : Thyroid. 16, 4, p. 375-380 6 p.

Research output: Contribution to journalArticle

85 Scopus citations

The kidney is an important site for in vivo phenylalanine-to-tyrosine conversion in adult humans: A metabolic role of the kidney

Møller, N., Meek, S., Bigelow, M., Andrews, J. & Nair, K. S., Feb 1 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 3, p. 1242-1246 5 p.

Research output: Contribution to journalArticle

59 Scopus citations

The protein-retaining effects of growth hormone during fasting involve inhibition of muscle-protein breakdown

Nørrelund, H., Sreekumaran Nair, K., Jørgensen, J. O. L., Christiansen, J. S. & Møller, N., Jan 1 2001, In : Diabetes. 50, 1, p. 96-104 9 p.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations

Thermic response to isoenergetic protein, carbohydrate or fat meals in lean and obese subjects

Nair, K. S., Halliday, D. & Garrow, J. S., Jan 1 1983, In : Clinical Science. 65, 3, p. 307-312 6 p.

Research output: Contribution to journalArticle

103 Scopus citations

Time-Restricted Eating Effects on Body Composition and Metabolic Measures in Humans who are Overweight: A Feasibility Study

Chow, L. S., Manoogian, E. N. C., Alvear, A., Fleischer, J. G., Thor, H., Dietsche, K., Wang, Q., Hodges, J. S., Esch, N., Malaeb, S., Harindhanavudhi, T., Nair, K. S., Panda, S. & Mashek, D. G., May 1 2020, In : Obesity. 28, 5, p. 860-869 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Tissue-specific regulation of mitochondrial and cytoplasmic protein synthesis rates by insulin

Boirie, Y., Short, K. R., Ahlman, B., Charlton, M. & Nair, K. S., Dec 2001, In : Diabetes. 50, 12, p. 2652-2658 7 p.

Research output: Contribution to journalArticle

Open Access
121 Scopus citations

Toward office-based measurement of gastric emptying in symptomatic diabetes diabetics using [13C]octanoic acid breath test

Lee, J. S., Camilleri, M., Zinsmeister, A. R., Burton, D. D., Choi, M. G., Nair, K. S. & Verlinden, M., Oct 30 2000, In : American Journal of Gastroenterology. 95, 10, p. 2751-2761 11 p.

Research output: Contribution to journalArticle

68 Scopus citations

Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women

Basu, R., Man, C. D., Campioni, M., Basu, A., Nair, K. S., Jensen, M. D., Khosla, S., Klee, G., Toffolo, G., Cobelli, C. & Rizza, R. A., Mar 2007, In : Diabetes. 56, 3, p. 753-766 14 p.

Research output: Contribution to journalArticle

44 Scopus citations

Type 2 diabetes impairs splanchnic uptake of glucose but does not alter intestinal glucose absorption during enteral glucose feeding: Additional evidence for a defect in hepatic glucokinase activity

Basu, A., Basu, R., Shah, P., Vella, A., Johnson, C. M., Jensen, M., Nair, K. S., Schwenk, W. F. & Rizza, R. A., 2001, In : Diabetes. 50, 6, p. 1351-1362 12 p.

Research output: Contribution to journalArticle

Open Access
121 Scopus citations

Unique cellular and mitochondrial defects mediate FK506-induced islet β-cell dysfunction

Rostambeigi, N., Lanza, I. R., Dzeja, P. P., Deeds, M. C., Irving, B. A., Reddi, H. V., Madde, P., Zhang, S., Asmann, Y. W., Anderson, J. M., Schimke, J. M., Nair, K. S., Eberhardt, N. L. & Kudva, Y. C., Mar 27 2011, In : Transplantation. 91, 6, p. 615-623 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Upper-body obese women are resistant to postprandial stimulation of protein synthesis

Liebau, F., Jensen, M. D., Nair, K. S. & Rooyackers, O., Oct 2014, In : Clinical Nutrition. 33, 5, p. 802-807 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Weight training improves walking endurance in healthy elderly persons

Ades, P. A., Ballor, D. L., Ashikaga, T., Utton, J. L. & Nair, K. S., 1996, In : Annals of internal medicine. 124, 6, p. 568-572 5 p.

Research output: Contribution to journalArticle

188 Scopus citations

Whole body and forearm substrate metabolism in hyperthyroidism: Evidence of increased basal muscle protein breakdown

Riis, A. L. D., Jørgensen, J. O. L., Gjedde, S., Nørrelund, H., Jurik, A. G., Nair, K. S., Ivarsen, P., Weeke, J. & Møller, N., Jun 1 2005, In : American Journal of Physiology - Endocrinology and Metabolism. 288, 6 51-6, p. E1067-E1073

Research output: Contribution to journalArticle

36 Scopus citations

Whole body protein kinetics using Phe and Tyr tracers: An evaluation of the accuracy of approximated flux values

Short, K. R., Meek, S. E., Moller, N., Ekberg, K. & Nair, K. S., Jun 1999, In : American Journal of Physiology - Endocrinology and Metabolism. 276, 6 39-6, p. E1194-E1200

Research output: Contribution to journalArticle

27 Scopus citations
Chapter

Alterations in protein metabolism in diabetes mellitus

Stump, C. S. & Nair, K. S., Nov 3 2011, Joslin's Diabetes Mellitus: Fourteenth Edition. Wolters Kluwer Health Adis (ESP), p. 275-290 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Chapter 20: Functional Assessment of Isolated Mitochondria In Vitro

Lanza, I. R. & Nair, K. S., 2009, Mitochondrial Function, Part B: Mitochondrial Protein Kinases, Protein Phosphatases and Mitochondrial Diseases. Allison, W. & Murphy, A. (eds.). B ed. p. 349-372 24 p. (Methods in Enzymology; vol. 457, no. B).

Research output: Chapter in Book/Report/Conference proceedingChapter

122 Scopus citations

Diabetes mellitus

Dhatariya, K. & Nair, K. S., Jan 1 2003, Metabolic and Therapeutic Aspects of Amino Acids in Clinical Nutrition, Second Edition. CRC Press, p. 355-374 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Measurement of synthesis rates of specific muscle proteins using needle biopsy samples.

Rooyackers, O. E., Balagopal, P. & Nair, K. S., 1997, Muscle & nerve. Supplement. Vol. 5.

Research output: Chapter in Book/Report/Conference proceedingChapter

Methods for investigation of protein and amino acid metabolism in diabetes mellitus

Albright, R. C. & Nair, K. S., Jan 1 2017, Methods for Investigation of Amino Acid and Protein Metabolism. CRC Press, p. 231-247 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sarcopenia of Aging and Its Metabolic Impact

Karakelides, H. & Nair, K. S., Dec 1 2005, Current Topics in Developmental Biology. Schatten, G. (ed.). p. 123-148 26 p. (Current Topics in Developmental Biology; vol. 68).

Research output: Chapter in Book/Report/Conference proceedingChapter

183 Scopus citations

The Effect of Insulin on Protein Metabolism

Greenlund, L. J. S. & Nair, K. S., Jun 2 2005, Insulin Resistance: Insulin Action and Its Disturbances in Disease. John Wiley and Sons Ltd, p. 105-132 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Comment/debate

Aging and diabetes: Mitochondrial dysfunction

Irving, B. A. & Sreekumaran Nair, K., Aug 1 2007, In : Current diabetes reports. 7, 4, p. 249-251 3 p.

Research output: Contribution to journalComment/debate

9 Scopus citations

Commentaries on viewpoint: Rejuvenation of the term sarcopenia

Langer, H. T., Mossakowski, A. A., Baar, K., Alcazar, J., Martin-Rincon, M., Alegre, L. M., Ara, I., Calbet, J. A. L., Hinkley, J. M., Coen, P. M., Irving, B. A., Allerton, T. D., Nair, S., Lima, R. M., Rey-López, J. P., Scott, D., Daly, R. M., Ebeling, P. R., Hayes, A., Tessier, A. J. & 10 others, Chevalier, S., Yates, B. A., Brown, L. A. R., Storer, T. W., Westcott, W. L., Nifli, A. P., Musci, R. V., Konopka, A. R., Hamilton, K. L. & Hepple less, R. T., Jan 1 2019, In : Journal of applied physiology. 126, 1, p. 257-262 6 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

DHEA: Luftschloss statt jungbrunnen

Translated title of the contribution: DHEA: Castle in the air rather than the fountain of youthResch, K. L. & Nair, K. S., Jun 1 2007, In : Forschende Komplementarmedizin. 14, 3, p. 185-186 2 p.

Research output: Contribution to journalComment/debate

Diabetes and protein metabolism

Møller, N. & Nair, K. S., Jan 1 2008, In : Diabetes. 57, 1, p. 3-4 2 p.

Research output: Contribution to journalComment/debate

31 Scopus citations

Endurance exercise as a countermeasure for aging (Diabetes (2008) 57, (2933-2942))

Lanza, I. R., Short, D. K., Short, K. R., Raghavakaimal, S., Basu, R., Joyner, M. J., McConnell, J. P. & Nair, K. S., Oct 2012, In : Diabetes. 61, 10, p. 2653 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Erratum: Asian Indians have enhanced skeletal muscle mitochondrial capacity to product ATP in association with severe insulin resistance (Diabetes (2008) 57 (1166-1175))

Nair, K. S., Bigelow, M. L., Asmann, Y. W., Chow, L. S., Coenen-Schimke, J. M., Klaus, K. A., Guo, Z. K., Sreekumar, R. & Irving, B. A., Mar 1 2009, In : Diabetes. 58, 3, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women (Diabetes (2007) 56, (753-766))

Basu, R., Man, C. D., Campioni, M., Basu, A., Nair, K. S., Jensen, M. D., Khosla, S., Klee, G., Toffolo, G., Cobelli, C. & Rizza, R. A., May 2007, In : Diabetes. 56, 5, p. 1486 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Erratum: Hyperglucagonemia Mitigates the Effect of Metformin on Glucose Production in Prediabetes (Cell Reports (2016) 15(7) (1394–1400) (S2211124716304375) (10.1016/j.celrep.2016.04.024))

Konopka, A. R., Esponda, R. R., Robinson, M. M., Johnson, M. L., Carter, R. E., Schiavon, M., Cobelli, C., Wondisford, F. E., Lanza, I. R. & Nair, K. S., May 22 2018, In : Cell reports. 23, 8, p. 2532 1 p.

Research output: Contribution to journalComment/debate

Publisher Correction: GDF15 mediates the effects of metformin on body weight and energy balance (Nature, (2019), 10.1038/s41586-019-1911-y)

Coll, A. P., Chen, M., Taskar, P., Rimmington, D., Patel, S., Tadross, J. A., Cimino, I., Yang, M., Welsh, P., Virtue, S., Goldspink, D. A., Miedzybrodzka, E. L., Konopka, A. R., Esponda, R. R., Huang, J. T. J., Tung, Y. C. L., Rodriguez-Cuenca, S., Tomaz, R. A., Harding, H. P., Melvin, A. & 13 others, Yeo, G. S. H., Preiss, D., Vidal-Puig, A., Vallier, L., Nair, K. S., Wareham, N. J., Ron, D., Gribble, F. M., Reimann, F., Sattar, N., Savage, D. B., Allan, B. B. & O’Rahilly, S., 2020, (Accepted/In press) In : Nature.

Research output: Contribution to journalComment/debate

Open Access