• 20708 Citations
  • 80 Scopus h-Index
1974 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Article

Hyperglucagonemia during insulin deficiency accelerates protein catabolism

Sreekumaran Nair, K., Halliday, D., Matthews, D. E. & Welle, S. L., Dec 1 1987, In : American Journal of Physiology - Endocrinology and Metabolism. 253, 2, p. 16/2

Research output: Contribution to journalArticle

52 Scopus citations
82 Scopus citations

Hyperglucagonemia Mitigates the Effect of Metformin on Glucose Production in Prediabetes

Konopka, A. R., Esponda, R. R., Robinson, M. M., Johnson, M. L., Carter, R. E., Schiavon, M., Cobelli, C., Wondisford, F. E., Lanza, I. R. & Nair, K. S., May 17 2016, In : Cell reports. 15, 7, p. 1394-1400 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Identification of amadori-modified plasma proteins in type 2 diabetes and the effect of short-term intensive insulin treatment

Jaleel, A., Halvatsiotis, P., Willlamson, B., Juhasz, P., Martin, S. & Nair, K. S., Mar 2005, In : Diabetes care. 28, 3, p. 645-652 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Identification of de novo synthesized and relatively older proteins: Accelerated oxidative damage to de novo synthesized apolipoprotein A-1 in type 1 diabetes

Jaleel, A., Henderson, G. C., Madden, B. J., Klaus, K. A., Morse, D. M., Gopala, S. & Nair, K. S., Oct 2010, In : Diabetes. 59, 10, p. 2366-2374 9 p.

Research output: Contribution to journalArticle

38 Scopus citations
9 Scopus citations

Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity

Short, K. R., Vittone, J. L., Bigelow, M. L., Proctor, D. N., Rizza, R. A., Coenen-Schimke, J. M. & Nair, K. S., Aug 1 2003, In : Diabetes. 52, 8, p. 1888-1896 9 p.

Research output: Contribution to journalArticle

435 Scopus citations

Impact of endurance training on murine spontaneous activity, muscle mitochondrial DNA abundance, gene transcripts, and function

Chow, L. S., Greenlund, L. J., Asmann, Y. W., Short, K. R., McCrady, S. K., Levine, J. A. & Nair, K. S., Mar 2007, In : Journal of applied physiology. 102, 3, p. 1078-1089 12 p.

Research output: Contribution to journalArticle

61 Scopus citations

Impact of exercise training on insulin sensitivity, physical fitness, and muscle oxidative capacity in first-degree relatives of type 2 diabetic patients

Østergård, T., Andersen, J. L., Nyholm, B., Lund, S., Nair, K. S., Saltin, B. & Schmitz, O., May 2006, In : American Journal of Physiology - Endocrinology and Metabolism. 290, 5, p. E998-E1005

Research output: Contribution to journalArticle

62 Scopus citations

Impact of high-fat diet and antioxidant supplement on mitochondrial functions and gene transcripts in rat muscle

Sreekumar, R., Unnikrishnan, J., Fu, A., Nygren, J., Short, K. R., Schimke, J., Barazzoni, R. & Nair, K. S., 2002, In : American Journal of Physiology - Endocrinology and Metabolism. 282, 5 45-5, p. E1055-E1061

Research output: Contribution to journalArticle

102 Scopus citations

Impact of insulin deprivation and treatment on sphingolipid distribution in different muscle subcellular compartments of streptozotocin-diabetic C57Bl/6 mice

Zabielski, P., Blachnio-Zabielska, A., Lanza, I. R., Gopala, S., Manjunatha, S., Jakaitis, D. R., Persson, X. M., Gransee, J., Klaus, K. A., Schimke, J. M., Jensen, M. D. & Nair, K. S., 2014, In : American Journal of Physiology - Endocrinology and Metabolism. 306, 5, p. E529-E542

Research output: Contribution to journalArticle

15 Scopus citations

Impact of long-term poor and good glycemic control on metabolomics alterations in type 1 diabetic people

Dutta, T., Kudva, Y. C., Persson, X. M. T., Schenck, L. A., Charles Ford, G., Singh, R. J., Carter, R. & Sreekumaran Nair, K., Mar 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 4, p. 1023-1033 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Impact of total body water errors on Kt/V estimates in children on peritoneal dialysis.

Morgenstern, B., Nair, K. S., Lerner, G., Neu, A., Quan, A. & Warady, B. A., 2001, In : Advances in peritoneal dialysis. Conference on Peritoneal Dialysis. 17, p. 260-263 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Impact of type 1 diabetes and insulin treatment on plasma levels and fractional synthesis rate of retinol-binding protein 4

Jourdan, M., Jaleel, A., Karakelides, H., Ford, G. C., Kahn, B. B. & Nair, K. S., Dec 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 5125-5130 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Impairment of phenylalanine conversion to tyrosine in end-stage renal disease causing tyrosine deficiency

Boirie, Y., Albright, R., Bigelow, M. & Nair, K. S., Aug 2004, In : Kidney international. 66, 2, p. 591-596 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
12 Scopus citations

Increased concentration of tracee affects estimates of muscle protein synthesis

Caso, G., Ford, G. C., Sreekumaran Nair, K., Vosswinkel, J. A., Garlick, P. J. & McNurlan, M. A., 2001, In : American Journal of Physiology - Endocrinology and Metabolism. 280, 6 43-6, p. E937-E946

Research output: Contribution to journalArticle

21 Scopus citations

Increased energy expenditure in poorly controlled Type 1 (insulin-dependent) diabetic patients

Nair, K. S., Halliday, D. & Garrow, J. S., Jul 1 1984, In : Diabetologia. 27, 1, p. 13-16 4 p.

Research output: Contribution to journalArticle

Open Access
88 Scopus citations

Induction of hyperandrogenism in lean reproductive-age women stimulates proatherogenic inflammation

González, F., Nair, K. S., Basal, E., Bearson, D. M., Schimke, J. M. & Blair, H. E., Sep 17 2014, In : Hormone and Metabolic Research. 47, 6, p. 439-444 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Influence of fish oil on skeletal muscle mitochondrial energetics and lipid metabolites during high-fat diet.

Lanza, I. R., Blachnio-Zabielska, A., Johnson, M. L., Schimke, J. M., Jakaitis, D. R., Lebrasseur, N. K., Jensen, M. D., Sreekumaran Nair, K. & Zabielski, P., Jun 15 2013, In : American journal of physiology. Endocrinology and metabolism. 304, 12, p. E1391-1403

Research output: Contribution to journalArticle

67 Scopus citations

Influence of frailty and health status on outcomes in patients with coronary disease undergoing percutaneous revascularization

Singh, M., Rihal, C. S., Lennon, R. J., Spertus, J. A., Nair, K. S. & Roger, V. L., Sep 2011, In : Circulation: Cardiovascular Quality and Outcomes. 4, 5, p. 496-502 7 p.

Research output: Contribution to journalArticle

145 Scopus citations

Influence of magnesium on the secretion and action of parathyroid hormone

Nair, K. S., Holdaway, I. M., Evans, M. C. & Cameron, A. D., Jul 1979, In : Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology. 2, 3, p. 267-270 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Insulin action during variable hyperglycemic-hyperinsulinemic infusions in hyperandrogenic anovulatory patients and healthy women

Dumesic, D. A., Abbott, D. H., Eisner, J. R., Nair, K. S. & Rizza, R. A., Sep 1 1999, In : Fertility and sterility. 72, 3, p. 458-466 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis

O'Neill, B. T., Lee, K. Y., Klaus, K., Softic, S., Krumpoch, M. T., Fentz, J., Stanford, K. I., Robinson, M. M., Cai, W., Kleinridders, A., Pereira, R. O., Hirshman, M. F., Abel, E. D., Accili, D., Goodyear, L. J., Nair, K. S. & Kahn, C. R., Sep 1 2016, In : Journal of Clinical Investigation. 126, 9, p. 3433-3446 14 p.

Research output: Contribution to journalArticle

42 Scopus citations

Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes

Ruegsegger, G. N., Manjunatha, S., Summer, P., Gopala, S., Zabeilski, P., Dasari, S., Vanderboom, P. M., Lanza, I. R., Klaus, K. A. & Nair, K. S., Mar 1 2019, In : FASEB Journal. 33, 3, p. 4458-4472 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Insulin does not stimulate protein synthesis acutely in prepubertal children with insulin-dependent diabetes mellitus

Vogiatzi, M. G., Nair, K. S., Beckett, P. R. & Copeland, K. C., 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 12, p. 4083-4087 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Insulin effect of leucine kinetics in Type 2 diabetes mellitus

Halvatsiotis, P. G., Turk, D., Alzaid, A., Dinneen, S., Rizza, R. A. & Nair, K. S., 2002, In : Diabetes, Nutrition and Metabolism - Clinical and Experimental. 15, 3, p. 136-142 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Insulin fails to enhance mTOR phosphorylation, mitochondrial protein synthesis, and ATP production in human skeletal muscle without amino acid replacement

Barazzoni, R., Short, K. R., Asmann, Y., Coenen-Schimke, J. M., Robinson, M. M. & Nair, K. S., Nov 1 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 303, 9, p. E1117-E1125

Research output: Contribution to journalArticle

30 Scopus citations

Insulin-mediated FFA suppression is associated with triglyceridemia and insulin sensitivity independent of adiposity

Bush, N. C., Basu, R., Rizza, R. A., Nair, K. S., Khosla, S. & Jensen, M. D., Nov 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 11, p. 4130-4138 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Insulin regulation of regional free fatty acid metabolism

Meek, S. E., Nair, K. S. & Jensen, M. D., Jan 1999, In : Diabetes. 48, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

131 Scopus citations

Insulin's effect on synthesis rates of liver proteins: A swine model comparing various precursors of protein synthesis

Ahlman, B., Charlton, M., Fu, A., Berg, C., O'Brien, P. & Nair, K. S., 2001, In : Diabetes. 50, 5, p. 947-954 8 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations

Interdependence of signal processing and analysis of urine1H NMR spectra for metabolic profiling

Zhang, S., Zheng, C., Lanza, I. R., Nair, K. S., Raftery, D. & Vitek, O., Aug 1 2009, In : Analytical Chemistry. 81, 15, p. 6080-6088 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

In vivo measurement of synthesis rate of individual skeletal muscle mitochondrial proteins

Jaleel, A., Short, K. R., Asmann, Y. W., Klaus, K. A., Morse, D. M., Ford, G. C. & Nair, K. S., Nov 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 5, p. E1255-E1268

Research output: Contribution to journalArticle

61 Scopus citations

In vivo measurement of synthesis rate of multiple plasma proteins in humans

Jaleel, A., Nehra, V., Persson, X. M. T., Boirie, Y., Bigelow, M. & Nair, K. S., 2006, In : American Journal of Physiology - Endocrinology and Metabolism. 291, 1, p. E190-E197

Research output: Contribution to journalArticle

24 Scopus citations
39 Scopus citations

John Stuart Garrow, MD, PhD, FRCP(E), FRCP (London) (1929-2016)

Bray, G. A. & Nair, S., 2016, (Accepted/In press) In : Obesity.

Research output: Contribution to journalArticle

Lack of dehydroepiandrosterone effect on a combined endurance and resistance exercise program in postmenopausal women

Igwebuike, A., Irving, B. A., Bigelow, M. L., Short, K. R., McConnell, J. P. & Nair, K. S., Feb 2008, In : Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 534-538 5 p.

Research output: Contribution to journalArticle

42 Scopus citations

Leucine, glucose, and energy metabolism after 3 days of fasting in healthy human subjects

Steekumaran Nair, K., Woolf, P. D., Welle, S. L. & Matthews, D. E., Jan 1 1987, In : American Journal of Clinical Nutrition. 46, 4, p. 557-562 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans

Nair, K. S., Schwartz, R. G. & Welle, S., 1992, In : American Journal of Physiology - Endocrinology and Metabolism. 263, 5 26-5, p. E928-E934

Research output: Contribution to journalArticle

181 Scopus citations

Leucine incorporation into mixed skeletal muscle protein in humans

Nair, K. S., Halliday, D. & Griggs, R. C., 1988, In : American Journal of Physiology - Endocrinology and Metabolism. 254, 2, p. 17/2

Research output: Contribution to journalArticle

123 Scopus citations

Leucine modulates dynamic phosphorylation events in insulin signaling pathway and enhances insulin-dependent glycogen synthesis in human skeletal muscle cells

Di Camillo, B., Eduati, F., Nair, S. K., Avogaro, A. & Toffolo, G. M., Mar 20 2014, In : BMC Cell Biology. 15, 1, 9.

Research output: Contribution to journalArticle

12 Scopus citations

LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force

Ferreira, D. M. S., Cheng, A. J., Agudelo, L. Z., Cervenka, I., Chaillou, T., Correia, J. C., Porsmyr-Palmertz, M., Izadi, M., Hansson, A., Martínez-Redondo, V., Valente-Silva, P., Pettersson-Klein, A. T., Estall, J. L., Robinson, M. M., Nair, K. S., Lanner, J. T. & Ruas, J. L., Oct 31 2019, In : Skeletal Muscle. 9, 1, 26.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Limited predictive ability of surrogate indices of insulin sensitivity/resistance in Asian-Indian men

Muniyappa, R., Irving, B. A., Unni, U. S., Briggs, W. M., Nair, K. S., Quon, M. J. & Kurpad, A. V., Dec 2010, In : American Journal of Physiology - Endocrinology and Metabolism. 299, 6, p. E1106-E1112

Research output: Contribution to journalArticle

13 Scopus citations

Mass spectrometric methods for determination of [13C]leucine enrichment in human muscle protein

Balagopal, P., Ford, G. C., Ebenstein, D. B., Nadeau, D. A. & Nair, K. S., Jul 15 1996, In : Analytical Biochemistry. 239, 1, p. 77-85 9 p.

Research output: Contribution to journalArticle

53 Scopus citations

Measurement of dermal collagen synthesis rate in vivo in humans

El-Harake, W. A., Furman, M. A., Cook, B., Nair, K. S., Kukowski, J. & Brodsky, I. G., Apr 1998, In : American Journal of Physiology - Endocrinology and Metabolism. 274, 4 37-4, p. E586-E591

Research output: Contribution to journalArticle

33 Scopus citations
62 Scopus citations

Measurement of synthesis rates of specific muscle proteins using needle biopsy samples

Rooyackers, O. E., Balagopal, P. & Nair, K. S., 1997, In : Muscle and Nerve. 20, SUPPL. 5, p. S93-S96

Research output: Contribution to journalArticle

31 Scopus citations

Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults

Johnson, M. L., Distelmaier, K., Lanza, I. R., Irving, B. A., Robinson, M. M., Konopka, A. R., Shulman, G. I. & Nair, K. S., Jan 2016, In : Diabetes. 65, 1, p. 74-84 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

Mechanism of glomerular hyperfiltration after a protein meal in humans

Nair, K. S., Pabico, R. C., Truglia, J. A., McKenna, B. A., Statt, M. & Lockwood, D. H., 1994, In : Diabetes care. 17, 7, p. 711-715 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Mechanism of insulin's anabolic effect on muscle: Measurements of muscle protein synthesis and breakdown using aminoacyl-tRNA and other surrogate measures

Chow, L. S., Albright, R. C., Bigelow, M. L., Toffolo, G., Cobelli, C. & Nair, K. S., 2006, In : American Journal of Physiology - Endocrinology and Metabolism. 291, 4, p. E729-E736

Research output: Contribution to journalArticle

81 Scopus citations