Research output per year
Research output per year
- 43 results
Search results
-
2023
Acidosis-induced regulation of adipocyte G0S2 promotes crosstalk between adipocytes and breast cancer cells as well as tumor progression
Cremer, J., Brohée, L., Dupont, L., Lefevre, C., Peiffer, R., Saarinen, A. M., Peulen, O., Bindels, L., Liu, J., Colige, A. & Deroanne, C. F., Aug 10 2023, In: Cancer Letters. 569, 216306.Research output: Contribution to journal › Article › peer-review
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HILPDA promotes NASH-driven HCC development by restraining intracellular fatty acid flux in hypoxia
Povero, D., Chen, Y., Johnson, S. M., McMahon, C. E., Pan, M., Bao, H., Petterson, X. M. T., Blake, E., Lauer, K. P., O'Brien, D. R., Yu, Y., Graham, R. P., Taner, T., Han, X., Razidlo, G. L. & Liu, J., Aug 2023, In: Journal of hepatology. 79, 2, p. 378-393 16 p.Research output: Contribution to journal › Article › peer-review
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Replacement of saturated fatty acids with linoleic acid in western diet attenuates atherosclerosis in a mouse model with inducible ablation of hepatic LDL receptor
Burr, S. D., Chen, Y., Hartley, C. P., Zhao, X. & Liu, J., Dec 2023, In: Scientific reports. 13, 1, 16832.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Identification of motifs and mechanisms for lipid droplet targeting of the lipolytic inhibitors G0S2 and HIG2
Campbell, L. E., Anderson, A. M., Chen, Y., Johnson, S. M., McMahon, C. E. & Liu, J., Dec 2022, In: Journal of cell science. 135, 24, jcs260236.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Biophysical characterization and a roadmap towards the NMR solution structure of G0S2, a key enzyme in non-alcoholic fatty liver disease
Moran, M. W., Ramirez, E. P., Zook, J. D., Saarinen, A. M., Baravati, B., Goode, M. R., Laloudakis, V., Kaschner, E. K., Olson, T. L., Craciunescu, F. M., Hansen, D. T., Liu, J. & Fromme, P., Jul 2021, In: PloS one. 16, 7 July, e0249164.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Hypoxia, hypoxia-inducible gene 2 (HIG2)/HILPDA, and intracellular lipolysis in cancer
Povero, D., Johnson, S. M. & Liu, J., Nov 28 2020, In: Cancer Letters. 493, p. 71-79 9 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
2019
Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G0/G1 switch gene 2 (G0S2)
Zhang, X., Xie, X., Heckmann, B. L., Saarinen, A. M., Gu, H., Zechner, R. & Liu, J., May 1 2019, In: FASEB Journal. 33, 5, p. 6655-6666 12 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2018
Regulation of lipolytic response and energy balance by melanocortin 2 receptor accessory protein (MRAP) in adipocytes
Zhang, X., Saarinen, A. M., Campbell, L. E., De Filippis, E. A. & Liu, J., Feb 1 2018, In: Diabetes. 67, 2, p. 222-234 13 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2017
Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet
Myers, C. E., Hoelzinger, D. B., Truong, T. N., Chew, L. A., Myles, A., Chaudhuri, L., Egan, J. B., Liu, J., Gendler, S. J. & Cohen, P. A., 2017, In: Oncotarget. 8, 3, p. 5426-5438 13 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
G0S2: A small giant controller of lipolysis and adipose-liver fatty acid flux
Zhang, X., Heckmann, B. L., Campbell, L. E. & Liu, J., Oct 2017, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1862, 10, p. 1146-1154 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access27 Scopus citations -
Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia
Zhang, X., Saarinen, A. M., Hitosugi, T., Wang, Z., Wang, L., Ho, T. H. & Liu, J., Dec 19 2017, In: eLife. 6, e31132.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 switch gene 2 expression
Heckmann, B. L., Zhang, X., Saarinen, A. M., Schoiswohl, G., Kershaw, E. E., Zechner, R. & Liu, J., Feb 23 2017, In: JCI Insight. 2, 4, e88735.Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Regulation of G0/G1 switch gene 2 (G0S2) protein ubiquitination and stability by triglyceride accumulation and ATGL interaction
Heckmann, B. L., Zhang, X., Saarinen, A. M. & Liu, J., Jun 2016, In: PloS one. 11, 6, e0156742.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2014
Defective adipose lipolysis and altered global energy metabolism in mice with adipose overexpression of the lipolytic inhibitor G0/G1 switch gene 2 (G0S2)
Heckmann, B. L., Zhang, X., Xie, X., Saarinen, A., Lu, X., Yang, X. & Liu, J., Jan 24 2014, In: Journal of Biological Chemistry. 289, 4, p. 1905-1916 12 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Identification of a novel phosphorylation site in adipose triglyceride lipase as a regulator of lipid droplet localization
Xie, X., Langlais, P., Zhang, X., Heckmann, B. L., Saarinen, A. M., Mandarino, L. J. & Liu, J., Jun 15 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 306, 12, p. E1449-E1459Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Regulation of fsp27 protein stability by ampk and HSC70
Zhang, X., Heckmann, B. L., Xie, X., Saarinen, A. M. & Liu, J., Dec 1 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 307, 11, p. E1047-E1056Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Targeted disruption of G0/G1 switch gene 2 enhances adipose lipolysis, alters hepatic energy balance, and alleviates high-fat diet-induced liver steatosis
Zhang, X., Xie, X., Heckmann, B. L., Saarinen, A. M., Czyzyk, T. A. & Liu, J., Mar 2014, In: Diabetes. 63, 3, p. 934-946 13 p.Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
2013
Distinct mechanisms regulate ATGL-mediated adipocyte lipolysis by lipid droplet coat proteins
Yang, X., Heckmann, B. L., Zhang, X., Smas, C. M. & Liu, J., 2013, In: Molecular Endocrinology. 27, 1, p. 116-126 11 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Erratum: Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein (Journal of Biological Chemistry (2011) 286 (15707-15715))
Wang, H., Bell, M., Sreenivasan, U., Hu, H., Liu, J., Dalen, K., Londos, C., Yamaguchi, T., Rizzo, M. A., Coleman, R., Gong, D., Brasaemle, D. & Sztalryd, C., Apr 12 2013, In: Journal of Biological Chemistry. 288, 15, p. 10952 1 p.Research output: Contribution to journal › Comment/debate › peer-review
2 Scopus citations -
Fatty liver accompanies an increase in lactobacillus species in the hind gut of C57BL/6 mice fed a high-fat diet
Zeng, H., Liu, J., Jackson, M. I., Zhao, F. Q., Yan, L. & Combs, G. F., May 2013, In: Journal of Nutrition. 143, 5, p. 627-631 5 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Studying lipolysis in adipocytes by combining siRNA knockdown and adenovirus-mediated overexpression approaches
Zhang, X., Heckmann, B. L. & Liu, J., 2013, Methods in Cell Biology. Academic Press Inc, p. 83-105 23 p. (Methods in Cell Biology; vol. 116).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access5 Scopus citations -
The autophagic inhibitor 3-methyladenine potently stimulates PKA-dependent lipolysis in adipocytes
Heckmann, B. L., Yang, X., Zhang, X. & Liu, J., Jan 2013, In: British Journal of Pharmacology. 168, 1, p. 163-171 9 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
The G0/G1 switch gene 2 (G0S2): Regulating metabolism and beyond
Heckmann, B. L., Zhang, X., Xie, X. & Liu, J., Feb 2013, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1831, 2, p. 276-281 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access58 Scopus citations -
2012
Identification of a role for CLASP2 in insulin action
Langlais, P. R., Dillon, J. L., Mengos, A., Baluch, D. P., Ardebili, R., Miranda, D. N., Xie, X., Heckmann, B. L., Liu, J. & Mandarino, L. J., Nov 9 2012, In: Journal of Biological Chemistry. 287, 46, p. 39245-39253 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Inverse regulation of basal lipolysis in perigonadal and mesenteric fat depots in mice
Wueest, S., Yang, X., Liu, J., Schoenle, E. J. & Konrad, D., Jan 2012, In: American Journal of Physiology - Endocrinology and Metabolism. 302, 1, p. E153-E160Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2011
Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes
Yang, X., Zhang, X., Heckmann, B. L., Lu, X. & Liu, J., Nov 25 2011, In: Journal of Biological Chemistry. 286, 47, p. 40477-40485 9 p.Research output: Contribution to journal › Article › peer-review
66 Scopus citations -
Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein
Wang, H., Bell, M., Sreenevasan, U., Hu, H., Liu, J., Dalen, K., Londos, C., Yamaguchi, T., Rizzo, M. A., Coleman, R., Gong, D., Brasaemle, D. & Sztalryd, C., May 6 2011, In: Journal of Biological Chemistry. 286, 18, p. 15707-15715 9 p.Research output: Contribution to journal › Article › peer-review
156 Scopus citations -
2010
Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2
Lu, X., Yang, X. & Liu, J., Jul 15 2010, In: Cell Cycle. 9, 14, p. 2791-2797 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access70 Scopus citations -
Identification of a novel splicing isoform of murine CGI-58
Yang, X., Lu, X. & Liu, J., Mar 5 2010, In: FEBS Letters. 584, 5, p. 903-910 8 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
The G0/G1 Switch Gene 2 Regulates Adipose Lipolysis through Association with Adipose Triglyceride Lipase
Yang, X., Lu, X., Lombès, M., Rha, G. B., Chi, Y. I., Guerin, T. M., Smart, E. J. & Liu, J., Mar 3 2010, In: Cell Metabolism. 11, 3, p. 194-205 12 p.Research output: Contribution to journal › Article › peer-review
296 Scopus citations -
2008
Diabetic HDL-associated myristic acid inhibits acetylcholine-induced nitric oxide generation by preventing the association of endothelial nitric oxide synthase with calmodulin
White, J., Guerin, T., Swanson, H., Post, S., Zhu, H., Gong, M., Liu, J., Everson, W. V., Li, X. A., Graf, G. A., Ballard, H. O., Ross, S. A. & Smart, E. J., Jan 2008, In: American Journal of Physiology - Cell Physiology. 294, 1, p. C295-C305Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
2007
Identification of CAP as a costameric protein that interacts with filamin C
Zhang, M., Liu, J., Cheng, A., DeYoung, S. M. & Saltiel, A. R., Dec 2007, In: Molecular biology of the cell. 18, 12, p. 4731-4740 10 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2006
CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motility
Zhang, M., Liu, J., Cheng, A., DeYoung, S. M., Chen, X., Dold, L. H. & Saltiel, A. R., Nov 15 2006, In: EMBO Journal. 25, 22, p. 5284-5293 10 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
2005
Changes in integrin expression during adipocyte differentiation
Liu, J., DeYoung, S. M., Zhang, M., Zhang, M., Cheng, A. & Saltiel, A. R., Sep 2005, In: Cell Metabolism. 2, 3, p. 165-177 13 p.Research output: Contribution to journal › Article › peer-review
118 Scopus citations -
The stomatin/prohibitin/flotillin/HflK/C domain of flotillin-1 contains distinct sequences that direct plasma membrane localization and protein interactions in 3T3-L1 adipocytes
Liu, J., DeYoung, S. M., Zhang, M., Dold, L. H. & Saltiel, A. R., Apr 22 2005, In: Journal of Biological Chemistry. 280, 16, p. 16125-16134 10 p.Research output: Contribution to journal › Article › peer-review
92 Scopus citations -
2003
Structural Basis for Recruitment of the Adaptor Protein APS to the Activated Insulin Receptor
Hu, J., Liu, J., Ghirlando, R., Saltiel, A. R. & Hubbard, S. R., Dec 2003, In: Molecular Cell. 12, 6, p. 1379-1389 11 p.Research output: Contribution to journal › Article › peer-review
92 Scopus citations -
The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport
Liu, J., DeYoung, S. M., Hwang, J. B., O'Leary, E. E. & Saltiel, A. R., Sep 19 2003, In: Journal of Biological Chemistry. 278, 38, p. 36754-36762 9 p.Research output: Contribution to journal › Article › peer-review
70 Scopus citations -
2002
APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes
Liu, J., Kimura, A., Baumann, C. A. & Saltiel, A. R., 2002, In: Molecular and cellular biology. 22, 11, p. 3599-3609 11 p.Research output: Contribution to journal › Article › peer-review
Open Access135 Scopus citations -
2001
Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit α4
Liu, J., Prickett, T. D., Elliott, E., Meroni, G. & Brautigan, D. L., Jun 5 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 12, p. 6650-6655 6 p.Research output: Contribution to journal › Article › peer-review
Open Access85 Scopus citations -
2000
Glycogen synthase association with the striated muscle glycogen-targeting subunit of protein phosphatase-1: Synthase activation involves scaffolding regulated by β-adrenergic signaling
Liu, J. & Brautigan, D. L., Aug 25 2000, In: Journal of Biological Chemistry. 275, 34, p. 26074-26081 8 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
Insulin-stimulated phosphorylation of the protein phosphatase-1 striated muscle glycogen-targeting subunit and activation of glycogen synthase
Liu, J. & Brautigan, D. L., May 26 2000, In: Journal of Biological Chemistry. 275, 21, p. 15940-15947 8 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Mutations of the serine phosphorylated in the protein phosphatase-1-binding motif in the skeletal muscle glycogen-targeting subunit
Liu, J., Wu, J., Oliver, C., Shenolikar, S. & Brautigan, D. L., Feb 15 2000, In: Biochemical Journal. 346, 1, p. 77-82 6 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
1998
A conserved domain for glycogen binding in protein phosphatase-1 targeting subunits
Wu, J., Liu, J., Thompson, I., Oliver, C. J., Shenolikar, S. & Brautigan, D. L., Nov 13 1998, In: FEBS Letters. 439, 1-2, p. 185-191 7 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations