• 2755 Citations
  • 28 Scopus h-Index
20122020

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Article
2020

Adipose-Derived Biogenic Nanoparticles for Suppression of Inflammation

Tian, M., Ticer, T., Wang, Q., Walker, S., Pham, A., Suh, A., Busatto, S., Davidovich, I., Al-Kharboosh, R., Lewis-Tuffin, L., Ji, B., Quinones-Hinojosa, A., Talmon, Y., Shapiro, S., Rückert, F. & Wolfram, J., Mar 1 2020, In : Small. 16, 10, 1904064.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

The solid progress of nanomedicine

Martins, J. P., das Neves, J., de la Fuente, M., Celia, C., Florindo, H., Günday-Türeli, N., Popat, A., Santos, J. L., Sousa, F., Schmid, R., Wolfram, J., Sarmento, B. & Santos, H. A., Jun 1 2020, In : Drug Delivery and Translational Research. 10, 3, p. 726-729 4 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
2019

Extracellular vesicle-based drug delivery systems for cancer treatment

Walker, S., Busatto, S., Pham, A., Tian, M., Suh, A., Carson, K., Quintero, A., Lafrence, M., Malik, H., Santana, M. X. & Wolfram, J., 2019, In : Theranostics. 9, 26, p. 8001-8017 17 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Organotropic drug delivery: Synthetic nanoparticles and extracellular vesicles

Busatto, S., Pham, A., Suh, A., Shapiro, S. & Wolfram, J., Jun 1 2019, In : Biomedical Microdevices. 21, 2, 46.

Research output: Contribution to journalArticle

14 Scopus citations

Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles

Nizzero, S., Li, F., Zhang, G., Venuta, A., Borsoi, C., Mai, J., Shen, H., Wolfram, J., Li, Z., Blanco, E. & Ferrari, M., Oct 1 2019, In : Acta Biomaterialia. 97, p. 501-512 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

A novel DNA aptamer for dual targeting of polymorphonuclear myeloid-derived suppressor cells and tumor cells

Liu, H., Mai, J., Shen, J., Wolfram, J., Li, Z., Zhang, G., Xu, R., Li, Y., Mu, C., Zu, Y., Li, X., Lokesh, G. L., Thiviyanathan, V., Volk, D. E., Gorenstein, D. G., Ferrari, M., Hu, Z. & Shen, H., 2018, In : Theranostics. 8, 1, p. 31-44 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

Chemotherapy sensitizes therapy-resistant cells to mild hyperthermia by suppressing heat shock protein 27 expression in triple-negative breast cancer

Mu, C., Wu, X., Zhou, X., Wolfram, J., Shen, J., Zhang, D., Mai, J., Xia, X., Holder, A. M., Ferrari, M., Liu, X. & Shen, H., Oct 1 2018, In : Clinical Cancer Research. 24, 19, p. 4900-4912 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin-Smith, G. K., Ayre, D. C., Bach, J. M., Bachurski, D., Baharvand, H., Balaj, L., Baldacchino, S., Bauer, N. N., Baxter, A. A., Bebawy, M., Beckham, C. & 362 others, Bedina Zavec, A., Benmoussa, A., Berardi, A. C., Bergese, P., Bielska, E., Blenkiron, C., Bobis-Wozowicz, S., Boilard, E., Boireau, W., Bongiovanni, A., Borràs, F. E., Bosch, S., Boulanger, C. M., Breakefield, X., Breglio, A. M., Brennan, M., Brigstock, D. R., Brisson, A., Broekman, M. L. D., Bromberg, J. F., Bryl-Górecka, P., Buch, S., Buck, A. H., Burger, D., Busatto, S., Buschmann, D., Bussolati, B., Buzás, E. I., Byrd, J. B., Camussi, G., Carter, D. R. F., Caruso, S., Chamley, L. W., Chang, Y. T., Chaudhuri, A. D., Chen, C., Chen, S., Cheng, L., Chin, A. R., Clayton, A., Clerici, S. P., Cocks, A., Cocucci, E., Coffey, R. J., Cordeiro-da-Silva, A., Couch, Y., Coumans, F. A. W., Coyle, B., Crescitelli, R., Criado, M. F., D’Souza-Schorey, C., Das, S., de Candia, P., De Santana, E. F., De Wever, O., del Portillo, H. A., Demaret, T., Deville, S., Devitt, A., Dhondt, B., Di Vizio, D., Dieterich, L. C., Dolo, V., Dominguez Rubio, A. P., Dominici, M., Dourado, M. R., Driedonks, T. A. P., Duarte, F. V., Duncan, H. M., Eichenberger, R. M., Ekström, K., EL Andaloussi, S., Elie-Caille, C., Erdbrügger, U., Falcón-Pérez, J. M., Fatima, F., Fish, J. E., Flores-Bellver, M., Försönits, A., Frelet-Barrand, A., Fricke, F., Fuhrmann, G., Gabrielsson, S., Gámez-Valero, A., Gardiner, C., Gärtner, K., Gaudin, R., Gho, Y. S., Giebel, B., Gilbert, C., Gimona, M., Giusti, I., Goberdhan, D. C. I., Görgens, A., Gorski, S. M., Greening, D. W., Gross, J. C., Gualerzi, A., Gupta, G. N., Gustafson, D., Handberg, A., Haraszti, R. A., Harrison, P., Hegyesi, H., Hendrix, A., Hill, A. F., Hochberg, F. H., Hoffmann, K. F., Holder, B., Holthofer, H., Hosseinkhani, B., Hu, G., Huang, Y., Huber, V., Hunt, S., Ibrahim, A. G. E., Ikezu, T., Inal, J. M., Isin, M., Ivanova, A., Jackson, H. K., Jacobsen, S., Jay, S. M., Jayachandran, M., Jenster, G., Jiang, L., Johnson, S. M., Jones, J. C., Jong, A., Jovanovic-Talisman, T., Jung, S., Kalluri, R., Kano, S. I., Kaur, S., Kawamura, Y., Keller, E. T., Khamari, D., Khomyakova, E., Khvorova, A., Kierulf, P., Kim, K. P., Kislinger, T., Klingeborn, M., Klinke, D. J., Kornek, M., Kosanović, M. M., Kovács, Á. F., Krämer-Albers, E. M., Krasemann, S., Krause, M., Kurochkin, I. V., Kusuma, G. D., Kuypers, S., Laitinen, S., Langevin, S. M., Languino, L. R., Lannigan, J., Lässer, C., Laurent, L. C., Lavieu, G., Lázaro-Ibáñez, E., Le Lay, S., Lee, M. S., Lee, Y. X. F., Lemos, D. S., Lenassi, M., Leszczynska, A., Li, I. T. S., Liao, K., Libregts, S. F., Ligeti, E., Lim, R., Lim, S. K., Linē, A., Linnemannstöns, K., Llorente, A., Lombard, C. A., Lorenowicz, M. J., Lörincz, Á. M., Lötvall, J., Lovett, J., Lowry, M. C., Loyer, X., Lu, Q., Lukomska, B., Lunavat, T. R., Maas, S. L. N., Malhi, H., Marcilla, A., Mariani, J., Mariscal, J., Martens-Uzunova, E. S., Martin-Jaular, L., Martinez, M. C., Martins, V. R., Mathieu, M., Mathivanan, S., Maugeri, M., McGinnis, L. K., McVey, M. J., Meckes, D. G., Meehan, K. L., Mertens, I., Minciacchi, V. R., Möller, A., Møller Jørgensen, M., Morales-Kastresana, A., Morhayim, J., Mullier, F., Muraca, M., Musante, L., Mussack, V., Muth, D. C., Myburgh, K. H., Najrana, T., Nawaz, M., Nazarenko, I., Nejsum, P., Neri, C., Neri, T., Nieuwland, R., Nimrichter, L., Nolan, J. P., Nolte-’t Hoen, E. N. M., Noren Hooten, N., O’Driscoll, L., O’Grady, T., O’Loghlen, A., Ochiya, T., Olivier, M., Ortiz, A., Ortiz, L. A., Osteikoetxea, X., Ostegaard, O., Ostrowski, M., Park, J., Pegtel, D. M., Peinado, H., Perut, F., Pfaffl, M. W., Phinney, D. G., Pieters, B. C. H., Pink, R. C., Pisetsky, D. S., Pogge von Strandmann, E., Polakovicova, I., Poon, I. K. H., Powell, B. H., Prada, I., Pulliam, L., Quesenberry, P., Radeghieri, A., Raffai, R. L., Raimondo, S., Rak, J., Ramirez, M. I., Raposo, G., Rayyan, M. S., Regev-Rudzki, N., Ricklefs, F. L., Robbins, P. D., Roberts, D. D., Rodrigues, S. C., Rohde, E., Rome, S., Rouschop, K. M. A., Rughetti, A., Russell, A. E., Saá, P., Sahoo, S., Salas-Huenuleo, E., Sánchez, C., Saugstad, J. A., Saul, M. J., Schiffelers, R. M., Schneider, R., Schøyen, T. H., Scott, A., Shahaj, E., Sharma, S., Shatnyeva, O., Shekari, F., Shelke, G. V., Shetty, A. K., Shiba, K., Siljander, P. R. M., Silva, A. M., Skowronek, A., Snyder, O. L., Soares, R. P., Sódar, B. W., Soekmadji, C., Sotillo, J., Stahl, P. D., Stoorvogel, W., Stott, S. L., Strasser, E. F., Swift, S., Tahara, H., Tewari, M., Timms, K., Tiwari, S., Tixeira, R., Tkach, M., Toh, W. S., Tomasini, R., Torrecilhas, A. C., Tosar, J. P., Toxavidis, V., Urbanelli, L., Vader, P., van Balkom, B. W. M., van der Grein, S. G., Van Deun, J., van Herwijnen, M. J. C., Van Keuren-Jensen, K., van Niel, G., van Royen, M. E., van Wijnen, A. J., Vasconcelos, M. H., Vechetti, I. J., Veit, T. D., Vella, L. J., Velot, É., Verweij, F. J., Vestad, B., Viñas, J. L., Visnovitz, T., Vukman, K. V., Wahlgren, J., Watson, D. C., Wauben, M. H. M., Weaver, A., Webber, J. P., Weber, V., Wehman, A. M., Weiss, D. J., Welsh, J. A., Wendt, S., Wheelock, A. M., Wiener, Z., Witte, L., Wolfram, J., Xagorari, A., Xander, P., Xu, J., Yan, X., Yáñez-Mó, M., Yin, H., Yuana, Y., Zappulli, V., Zarubova, J., Žėkas, V., Zhang, J. Y., Zhao, Z., Zheng, L., Zheutlin, A. R., Zickler, A. M., Zimmermann, P., Zivkovic, A. M., Zocco, D. & Zuba-Surma, E. K., Jan 1 2018, In : Journal of Extracellular Vesicles. 7, 1, 1535750.

Research output: Contribution to journalArticle

957 Scopus citations
2017

A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery

Wolfram, J., Nizzero, S., Liu, H., Li, F., Zhang, G., Li, Z., Shen, H., Blanco, E. & Ferrari, M., Dec 1 2017, In : Scientific reports. 7, 1, 13738.

Research output: Contribution to journalArticle

42 Scopus citations

A Liposome Encapsulated Ruthenium Polypyridine Complex as a Theranostic Platform for Triple-Negative Breast Cancer

Shen, J., Kim, H. C., Wolfram, J., Mu, C., Zhang, W., Liu, H., Xie, Y., Mai, J., Zhang, H., Li, Z., Guevara, M., Mao, Z. W. & Shen, H., May 10 2017, In : Nano Letters. 17, 5, p. 2913-2920 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

Contribution of Kupffer cells to liposome accumulation in the liver

Samuelsson, E., Shen, H., Blanco, E., Ferrari, M. & Wolfram, J., Oct 1 2017, In : Colloids and Surfaces B: Biointerfaces. 158, p. 356-362 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Multi-step encapsulation of chemotherapy and gene silencing agents in functionalized mesoporous silica nanoparticles

Shen, J., Liu, H., Mu, C., Wolfram, J., Zhang, W., Kim, H. C., Zhu, G., Hu, Z., Ji, L. N., Liu, X., Ferrari, M., Mao, Z. W. & Shen, H., Apr 28 2017, In : Nanoscale. 9, 16, p. 5329-5341 13 p.

Research output: Contribution to journalArticle

31 Scopus citations
2016

A Micro/Nano Composite for Combination Treatment of Melanoma Lung Metastasis

Mi, Y., Mu, C., Wolfram, J., Deng, Z., Hu, T. Y., Liu, X., Blanco, E., Shen, H. & Ferrari, M., Apr 20 2016, In : Advanced Healthcare Materials. 5, 8, p. 936-946 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

A pyruvate decarboxylase-mediated therapeutic strategy for mimicking yeast metabolism in cancer cells

Scott, B., Shen, J., Nizzero, S., Boom, K., Persano, S., Mi, Y., Liu, X., Zhao, Y., Blanco, E., Shen, H., Ferrari, M. & Wolfram, J., Sep 1 2016, In : Pharmacological Research. 111, p. 413-421 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Enzyme-responsive multistage vector for drug delivery to tumor tissue

Mi, Y., Wolfram, J., Mu, C., Liu, X., Blanco, E., Shen, H. & Ferrari, M., Nov 1 2016, In : Pharmacological Research. 113, p. 92-99 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Hesperetin liposomes for cancer therapy

Wolfram, J., Scott, B., Boom, K., Shen, J., Borsoi, C., Suri, K., Grande, R., Fresta, M., Celia, C., Zhao, Y., Shen, H. & Ferrari, M., Aug 1 2016, In : Current Drug Delivery. 13, 5, p. 711-719 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Label-Free Isothermal Amplification Assay for Specific and Highly Sensitive Colorimetric miRNA Detection

Persano, S., Guevara, M. L., Wolfram, J., Blanco, E., Shen, H., Ferrari, M. & Pompa, P. P., Sep 30 2016, In : ACS Omega. 1, 3, p. 448-455 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2015

Connective tissue growth factor stimulates the proliferation, migration and differentiation of lung fibroblasts during paraquat-induced pulmonary fibrosis

Yang, Z., Sun, Z., Liu, H., Ren, Y., Shao, D., Zhang, W., Lin, J., Wolfram, J., Wang, F. & Nie, S., Jul 1 2015, In : Molecular Medicine Reports. 12, 1, p. 1091-1097 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Multistage vector (MSV) therapeutics

Wolfram, J., Shen, H. & Ferrari, M., Dec 10 2015, In : Journal of Controlled Release. 219, p. 406-415 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Multistage vector delivery of sulindac and silymarin for prevention of colon cancer

Scavo, M. P., Gentile, E., Wolfram, J., Gu, J., Barone, M., Evangelopoulos, M., Martinez, J. O., Liu, X., Celia, C., Tasciotti, E., Vilar, E. & Shen, H., Dec 1 2015, In : Colloids and Surfaces B: Biointerfaces. 136, p. 694-703 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Polyethylene glycol (PEG)-dendron phospholipids as innovative constructs for the preparation of super stealth liposomes for anticancer therapy

Pasut, G., Paolino, D., Celia, C., Mero, A., Joseph, A. S., Wolfram, J., Cosco, D., Schiavon, O., Shen, H. & Fresta, M., Feb 10 2015, In : Journal of Controlled Release. 199, p. 106-113 8 p.

Research output: Contribution to journalArticle

79 Scopus citations

Porous silicon microparticles for delivery of siRNA therapeutics

Shen, J., Wu, X., Lee, Y., Wolfram, J., Yang, Z., Mao, Z. W., Ferrari, M. & Shen, H., Jan 15 2015, In : Journal of Visualized Experiments. 95, e52075.

Research output: Contribution to journalArticle

30 Scopus citations

Protective effects of intestinal trefoil factor (ITF) on gastric mucosal epithelium through activation of extracellular signal-regulated kinase 1/2 (ERK1/2)

Lin, J., Sun, Z., Zhang, W., Liu, H., Shao, D., Ren, Y., Wen, Y., Cao, L., Wolfram, J., Yang, Z. & Nie, S., Jun 18 2015, In : Molecular and Cellular Biochemistry. 404, 1-2, p. 263-270 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Cyclodextrin and polyethylenimine functionalized mesoporous silica nanoparticles for delivery of siRNA cancer therapeutics

Shen, J., Kim, H. C., Su, H., Wang, F., Wolfram, J., Kirui, D., Mai, J., Mu, C., Ji, L. N., Mao, Z. W. & Shen, H., 2014, In : Theranostics. 4, 5, p. 487-497 11 p.

Research output: Contribution to journalArticle

123 Scopus citations

Differences in the aerobic capacity of flight muscles between butterfly populations and species with dissimilar flight abilities

Rauhamäki, V., Wolfram, J., Jokitalo, E., Hanski, I. & Dahlhoff, E. P., Jan 8 2014, In : PloS one. 9, 1, e78069.

Research output: Contribution to journalArticle

7 Scopus citations

Evaluation of anticancer activity of celastrol liposomes in prostate cancer cells

Wolfram, J., Suri, K., Huang, Y., Molinaro, R., Borsoi, C., Scott, B., Boom, K., Paolino, D., Fresta, M., Wang, J., Ferrari, M., Celia, C. & Shen, H., 2014, In : Journal of Microencapsulation. 31, 5, p. 501-507 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Mechanistic features of nanodiamonds in the lapping of magnetic heads

Jiang, X., Chen, Z., Wolfram, J. & Yang, Z., 2014, In : Scientific World Journal. 2014, 326427.

Research output: Contribution to journalArticle

1 Scopus citations

Multifunctional gold nanorods for siRNA gene silencing and photothermal therapy

Shen, J., Kim, H. C., Mu, C., Gentile, E., Mai, J., Wolfram, J., Ji, L. N., Ferrari, M., Mao, Z. W. & Shen, H., Oct 1 2014, In : Advanced Healthcare Materials. 3, 10, p. 1629-1637 9 p.

Research output: Contribution to journalArticle

73 Scopus citations

Polyarginine induces an antitumor immune response through binding to toll-like receptor 4

Yang, Y., Wolfram, J., Fang, X., Shen, H. & Ferrari, M., Apr 9 2014, In : Small. 10, 7, p. 1250-1254 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Safety of nanoparticles in medicine

Wolfram, J., Zhu, M., Yang, Y., Shen, J., Gentile, E., Paolino, D., Fresta, M., Nie, G., Chen, C., Shen, H., Ferrari, M. & Zhao, Y., Jan 1 2014, In : Current Drug Targets. 15, 10, A001.

Research output: Contribution to journalArticle

10 Scopus citations

Shrinkage of pegylated and non-pegylated liposomes in serum

Wolfram, J., Suri, K., Yang, Y., Shen, J., Celia, C., Fresta, M., Zhao, Y., Shen, H. & Ferrari, M., Feb 1 2014, In : Colloids and Surfaces B: Biointerfaces. 114, p. 294-300 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Targeting the thyroid gland with thyroid-stimulating hormone (TSH)-nanoliposomes

Paolino, D., Cosco, D., Gaspari, M., Celano, M., Wolfram, J., Voce, P., Puxeddu, E., Filetti, S., Celia, C., Ferrari, M., Russo, D. & Fresta, M., Aug 2014, In : Biomaterials. 35, 25, p. 7101-7109 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

The impact of lubricants on the precision lapping process

Jiang, X., Chen, Z., Wolfram, J., Wei, Z., Shen, Y. & Yang, Z., Sep 30 2014, In : Microscopy and Microanalysis. 20, 6, p. 1708-1714 7 p.

Research output: Contribution to journalArticle

The nano-plasma interface: Implications of the protein corona

Wolfram, J., Yang, Y., Shen, J., Moten, A., Chen, C., Shen, H., Ferrari, M. & Zhao, Y., Dec 1 2014, In : Colloids and Surfaces B: Biointerfaces. 124, p. 17-24 8 p.

Research output: Contribution to journalArticle

103 Scopus citations
2013

Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells

Celia, C., Trapasso, E., Locatelli, M., Navarra, M., Ventura, C. A., Wolfram, J., Carafa, M., Morittu, V. M., Britti, D., Di Marzio, L. & Paolino, D., Dec 1 2013, In : Colloids and Surfaces B: Biointerfaces. 112, p. 548-553 6 p.

Research output: Contribution to journalArticle

79 Scopus citations

Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells

Yang, Y., Wolfram, J., Boom, K., Fang, X., Shen, H. & Ferrari, M., Jul 2013, In : Cell Biochemistry and Function. 31, 5, p. 374-379 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

High capacity nanoporous silicon carrier for systemic delivery of gene silencing therapeutics

Shen, J., Xu, R., Mai, J., Kim, H. C., Guo, X., Qin, G., Yang, Y., Wolfram, J., Mu, C., Xia, X., Gu, J., Liu, X., Mao, Z. W., Ferrari, M. & Shen, H., Nov 26 2013, In : ACS Nano. 7, 11, p. 9867-9880 14 p.

Research output: Contribution to journalArticle

81 Scopus citations

Liposomal chemotherapeutics

Gentile, E., Cilurzo, F., Di Marzio, L., Carafa, M., Ventura, C. A., Wolfram, J., Paolino, D. & Celia, C., Dec 1 2013, In : Future Oncology. 9, 12, p. 1849-1859 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane

Yang, Y., Wolfram, J., Shen, J., Zhao, Y., Fang, X., Shen, H. & Ferrari, M., Dec 11 2013, In : FEBS Letters. 587, 24, p. 3912-3920 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
2012

Hesperetin: An inhibitor of the transforming growth factor-β (TGF-β) signaling pathway

Yang, Y., Wolfram, J., Shen, H., Fang, X. & Ferrari, M., Dec 2012, In : European Journal of Medicinal Chemistry. 58, p. 390-395 6 p.

Research output: Contribution to journalArticle

28 Scopus citations