• 15354 Citations
  • 65 Scopus h-Index
1975 …2019
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Research Output 1987 2019

2019

A practical guide to test blueprinting

Raymond, M. R. & Grande, J. P., Jan 1 2019, In : Medical Teacher.

Research output: Contribution to journalArticle

instruction
learning

CRRL269

Chen, Y., Harty, G. J., Zheng, Y., Iyer, S. R., Sugihara, S., Sangaralingham, S. J., Ichiki, T., Grande, J. P., Lee, H. C., Wang, X. & Burnett, J. C. J., May 10 2019, In : Circulation research. 124, 10, p. 1462-1472 11 p.

Research output: Contribution to journalArticle

Open Access
Acute Kidney Injury
C-Type Natriuretic Peptide
Kidney
Apoptosis
Protective Agents

Crystalglobulin-Induced Nephropathy and Keratopathy

D'Costa, M. R., Dalvin, L. A., Manohar, S., Maguire, L. J., Grande, J. P., Gonsalves, W., Nasr, S. H. & Hogan, M. C., Mar 1 2019, In : Kidney Medicine. 1, 2, p. 71-74 4 p.

Research output: Contribution to journalArticle

Open Access
Paraproteinemias
Kidney
Thrombotic Microangiopathies
Malignant Hypertension
Biopsy

Long-term follow-up of the DeKAF cross-sectional cohort study

Matas, A. J., Fieberg, A., Mannon, R. B., Leduc, R., Grande, J. P., Kasiske, B. L., Cecka, M., Gaston, R., Hunsicker, L., Connett, J., Cosio, F. G., Gourishankar, S. & Rush, D., Jan 1 2019, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle

Graft Survival
Cohort Studies
Cross-Sectional Studies
Transplants
Inflammation
1 Citation (Scopus)
Neuropilin-1
Endothelial cells
Angiotensin II
Endothelial Cells
Hypertension

Relationship between ETS Transcription Factor ETV1 and TGF-β-regulated SMAD Proteins in Prostate Cancer

Oh, S., Shin, S., Song, H., Grande, J. P. & Janknecht, R., Dec 1 2019, In : Scientific reports. 9, 1, 8186.

Research output: Contribution to journalArticle

Open Access
Prostate
Prostatic Neoplasms
Transcription Factors
Transgenic Mice
Prostatic Intraepithelial Neoplasia

Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups

the DeKAF Genomics and GEN03 Investigators, Jan 1 2019, In : American Journal of Transplantation.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Tacrolimus
North American Indians
Kidney
African Americans
7 Citations (Scopus)

Targeting senescent cells alleviates obesity-induced metabolic dysfunction

Palmer, A. K., Xu, M., Zhu, Y., Pirtskhalava, T., Weivoda, M., Hachfeld, C. M., Prata, L. G., van Dijk, T. H., Verkade, E., Casaclang-Verzosa, G., Johnson, K. O., Cubro, H., Doornebal, E. J., Ogrodnik, M., Jurk, D., Jensen, M. D., Chini, E. N., Miller, J. D., Matveyenko, A. V., Stout, M. B. & 13 others, Schafer, M. J., White, T. A., Hickson, L., Demaria, M., Garovic, V. D., Grande, J. P., Arriaga, E. A., Kuipers, F., von Zglinicki, T., LeBrasseur, N. K., Campisi, J., Tchkonia, T. & Kirkland, J. L., Jun 1 2019, In : Aging Cell. 18, 3, e12950.

Research output: Contribution to journalArticle

Open Access
Obesity
Adipose Tissue
Obese Mice
Insulin Resistance
p16 Genes

The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, Jan 1 2019, In : American Journal of Transplantation.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Transplants
Kidney
Population
Genome-Wide Association Study

The sensitivity and specificity of the routine kidney biopsy immunofluorescence panel are inferior to diagnosing renal immunoglobulin-derived amyloidosis by mass spectrometry

Gonzalez Suarez, M. L., Zhang, P., Nasr, S. H., Sathick, I. J., Kittanamongkolchai, W., Kurtin, P. J., Alexander, M. P., Cornell, L. D., Fidler, M. E., Grande, J. P., Herrera Hernandez, L. P., Said, S. M., Sethi, S. M., Dispenzieri, A., Gertz, M. & Leung, N., Jan 1 2019, (Accepted/In press) In : Kidney international.

Research output: Contribution to journalArticle

Amyloidosis
Fluorescent Antibody Technique
Immunoglobulins
Mass Spectrometry
Kidney
2018
5 Citations (Scopus)

Ccl2 deficiency protects against chronic renal injury in murine renovascular hypertension

Kashyap, S., Osman, M., Ferguson, C. M., Nath, M. C., Roy, B., Lien, K. R., Nath, K. A., Garovic, V. D., Lerman, L. O. & Grande, J. P., Dec 1 2018, In : Scientific Reports. 8, 1, 8598.

Research output: Contribution to journalArticle

Renovascular Hypertension
Knockout Mice
Kidney
Wounds and Injuries
Renal Artery Obstruction
7 Citations (Scopus)

Congophilic Fibrillary Glomerulonephritis: A Case Series

Alexander, M. P., Dasari, S., Vrana, J. A., Riopel, J., Valeri, A. M., Markowitz, G. S., Hever, A., Bijol, V., Larsen, C. P., Cornell, L. D., Fidler, M. E., Said, S. M., Sethi, S. M., Herrera Hernandez, L. P., Grande, J. P., Erickson, S. B., Fervenza, F. C., Leung, N., Kurtin, P. J. & Nasr, S. H., Jan 1 2018, (Accepted/In press) In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Glomerulonephritis
Amyloidosis
Mass Spectrometry
Congo
Immunohistochemistry
13 Citations (Scopus)

DNAJB9 Is a Specific Immunohistochemical Marker for Fibrillary Glomerulonephritis

Nasr, S. H., Vrana, J. A., Dasari, S., Bridoux, F., Fidler, M. E., Kaaki, S., Quellard, N., Rinsant, A., Goujon, J. M., Sethi, S. M., Fervenza, F. C., Cornell, L. D., Said, S. M., McPhail, E., Herrera Hernandez, L. P., Grande, J. P., Hogan, M. C., Lieske, J. C., Leung, N., Kurtin, P. J. & 1 others, Alexander, M. P., Jan 1 2018, In : Kidney International Reports. 3, 1, p. 56-64 9 p.

Research output: Contribution to journalArticle

Glomerulonephritis
Staining and Labeling
Immunoelectron Microscopy
Amyloidosis
Healthy Volunteers
1 Citation (Scopus)
Tacrolimus
African Americans
Phenotype
Kidney
Genomics
4 Citations (Scopus)

Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney

Puranik, A. S., Leaf, I. A., Jensen, M. A., Hedayat, A. F., Saad, A., Kim, K. W., Saadalla, A. M., Woollard, J. R., Kashyap, S., Textor, S. C., Grande, J. P., Lerman, A., Simari, R. D., Randolph, G. J., Duffield, J. S. & Lerman, L. O., Dec 1 2018, In : Scientific Reports. 8, 1, 13948.

Research output: Contribution to journalArticle

Renal Artery Obstruction
Macrophages
Kidney
Parabiosis
Endothelial Cells
2 Citations (Scopus)

Renal Disorders in Pregnancy: Core Curriculum 2019

Gonzalez Suarez, M. L., Kattah, A., Grande, J. P. & Garovic, V. D., Jan 1 2018, (Accepted/In press) In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Curriculum
Kidney
Pregnancy
Kidney Diseases
Chronic Renal Insufficiency
7 Citations (Scopus)

Role of TLR4 signaling in the nephrotoxicity of Heme and heme proteins

Nath, K. A., Belcher, J. D., Nath, M. C., Grande, J. P., Croatt, A. J., Ackerman, A. W., Katusic, Z. S. & Vercellotti, G. M., Jan 1 2018, In : American Journal of Physiology - Renal Physiology. 314, 5, p. F906-F914

Research output: Contribution to journalArticle

Hemeproteins
Toll-Like Receptor 4
Heme
Acute Kidney Injury
Kidney
2 Citations (Scopus)

The murine dialysis fistula model exhibits a senescence phenotype: pathobiological mechanisms and therapeutic potential

Nath, K. A., O'Brien, D. R., Croatt, A. J., Grande, J. P., Ackerman, A. W., Nath, M. C., Yamada, S., Terzic, A., Tchkonia, T., Kirkland, J. L. & Katusic, Z. S., Nov 1 2018, In : American journal of physiology. Renal physiology. 315, 5, p. F1493-F1499

Research output: Contribution to journalArticle

Arteriovenous Fistula
Fistula
Chronic Renal Insufficiency
Dialysis
Phenotype
2017
1 Citation (Scopus)

An Unusual Case of Acute Myeloid Leukemia Cell Infiltration of the Renal Allograft: A Case Report and Review of Literature

Manohar, S., Sathick, I. J., Grande, J. P., El-Zoghby, Z. M. & Leung, N., Sep 1 2017, In : Transplantation Proceedings. 49, 7, p. 1578-1582 5 p.

Research output: Contribution to journalArticle

Myeloid Cells
Acute Myeloid Leukemia
Allografts
Kidney
Leukemic Infiltration
2 Citations (Scopus)

Cardiovascular phenotype in Smad3 deficient mice with renovascular hypertension

Kashyap, S., Warner, G., Hu, Z., Gao, F., Osman, M., Al Saiegh, Y., Lien, K. R., Nath, K. A. & Grande, J. P., Oct 1 2017, In : PLoS One. 12, 10, e0187062.

Research output: Contribution to journalArticle

Renovascular Hypertension
Surgery
hypertension
Dissection
Phenotype
3 Citations (Scopus)

Heat stress induced, ligand-independent MET and EGFR signalling in hepatocellular carcinoma

Thompson, S. M., Jondal, D. E., Butters, K. A., Knudsen, B. E., Anderson, J. L., Stokes, M. P., Jia, X., Grande, J. P., Roberts, L. R., Callstrom, M. R. & Woodrum, D. A., Nov 6 2017, (Accepted/In press) In : International Journal of Hyperthermia. p. 1-12 12 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Hot Temperature
Ligands
Intercellular Signaling Peptides and Proteins
Phosphorylation
9 Citations (Scopus)

Late graft failure after kidney transplantation as the consequence of late versus early events

Gaston, R. S., Fieberg, A., Hunsicker, L., Kasiske, B. L., Leduc, R., Cosio, F. G., Gourishankar, S., Grande, J. P., Mannon, R. B., Rush, D., Cecka, J. M., Connett, J. & Matas, A. J., Jan 1 2017, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle

Kidney Transplantation
Transplants
Creatinine
Delayed Graft Function
Serum
18 Citations (Scopus)

Noninvasive assessment of renal fibrosis with magnetization transfer MR imaging: Validation and evaluation in murine renal artery stenosis

Jiang, K., Ferguson, C. M., Ebrahimi, B., Tang, H., Kline, T., Burningham, T. A., Mishra, P. K., Grande, J. P., Macura, S. I. & Lerman, L. O., Apr 1 2017, In : Radiology. 283, 1, p. 77-86 10 p.

Research output: Contribution to journalArticle

Renal Artery Obstruction
Fibrosis
Kidney
Hydroxyproline
Blood Volume
12 Citations (Scopus)

Urinary extracellular vesicles of podocyte origin and renal injury in preeclampsia

Gilani, S. I., Anderson, U. D., Jayachandran, M., Weissgerber, T. L., Zand, L., White, W. M., Milic, N., Suarez, M. L. G., Vallapureddy, R. R., Nääv, Å., Erlandsson, L., Lieske, J. C., Grande, J. P., Nath, K. A., Hansson, S. R. & Garovic, V. D., Nov 1 2017, In : Journal of the American Society of Nephrology. 28, 11, p. 3363-3372 10 p.

Research output: Contribution to journalArticle

Podocytes
Pre-Eclampsia
Kidney
Wounds and Injuries
Hemopexin
2016
15 Citations (Scopus)
Heme Oxygenase-1
Arteriovenous Fistula
Chronic Renal Insufficiency
Up-Regulation
Viral Genes
4 Citations (Scopus)

An online app platform enhances collaborative medical student group learning and classroom management

Peacock, J. G. & Grande, J. P., Feb 1 2016, In : Medical Teacher. 38, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

Medical Students
medical student
Learning
Students
classroom
13 Citations (Scopus)

Blockade of CCR2 reduces macrophage influx and development of chronic renal damage in murine renovascular hypertension

Kashyap, S., Warner, G. M., Hartono, S. P., Boyilla, R., Knudsen, B. E., Zubair, A. S., Lien, K., Nath, K. A., Textor, S. C., Lerman, L. O. & Grande, J. P., Mar 1 2016, In : American Journal of Physiology - Renal Physiology. 310, 5, p. F372-F384

Research output: Contribution to journalArticle

Renovascular Hypertension
Chemokine Receptors
Macrophages
Kidney
Atrophy
1 Citation (Scopus)

Cardiovascular manifestations of renovascular hypertension in diabetic mice

Kashyap, S., Engel, S., Osman, M., Al-Saiegh, Y., Wongjarupong, A. & Grande, J. P., 2016, In : PeerJ. 2016, 2, 1736.

Research output: Contribution to journalArticle

Renovascular Hypertension
Renal Artery Obstruction
Medical problems
arteries
Surgery
2 Citations (Scopus)

Development of renal atrophy in murine 2 kidney 1 clip hypertension is strain independent

Kashyap, S., Boyilla, R., Zaia, P. J., Ghossan, R., Nath, K. A., Textor, S. C., Lerman, L. O. & Grande, J. P., Aug 1 2016, In : Research in Veterinary Science. 107, p. 171-177 7 p.

Research output: Contribution to journalArticle

atrophy
Surgical Instruments
hypertension
Atrophy
kidneys
13 Citations (Scopus)

Heat Stress-InducedPI3K/mTORC2-Dependent AKT signaling is a central mediator of hepatocellular carcinoma survival to thermal ablation induced heat stress

Thompson, S. M., Callstrom, M. R., Jondal, D. E., Butters, K. A., Knudsen, B. E., Anderson, J. L., Lien, K. R., Sutor, S. L., Lee, J. S., Thorgeirsson, S. S., Grande, J. P., Roberts, L. R. & Woodrum, D. A., Sep 1 2016, In : PLoS One. 11, 9, e0162634.

Research output: Contribution to journalArticle

hepatoma
Ablation
heat stress
Hepatocellular Carcinoma
Hot Temperature
27 Citations (Scopus)

Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1

Kim, T. D., Jin, F., Shin, S., Oh, S., Lightfoot, S. A., Grande, J. P., Johnson, A. J., Van Deursen, J., Wren, J. D. & Janknecht, R., Feb 1 2016, In : Journal of Clinical Investigation. 126, 2, p. 706-720 15 p.

Research output: Contribution to journalArticle

Histone Demethylases
Prostate
Carcinogenesis
Transcription Factors
Prostatic Neoplasms
12 Citations (Scopus)

Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-α ratio and attenuating T-cell infiltration

Patil, C. N., Wallace, K., La Marca, B. D., Moulana, M., Lopez-Ruiz, A., Soljancic, A., Juncos, L. A., Grande, J. P. & Reckelhoff, J. F., Aug 1 2016, In : American Journal of Physiology - Renal Physiology. 311, 2, p. F395-F403

Research output: Contribution to journalArticle

Reperfusion Injury
Interleukin-10
Testosterone
T-Lymphocytes
Kidney
11 Citations (Scopus)

Predictors of medical school clerkship performance: A multispecialty longitudinal analysis of standardized examination scores and clinical assessments

Casey, P. M., Palmer, B. A., Thompson, G. B., Laack, T. A., Thomas, M. R., Hartz, M. F., Jensen, J. R., Sandefur, B. J., Hammack, J. E., Swanson, J. W., Sheeler, R. D. & Grande, J. P., Apr 27 2016, In : BMC Medical Education. 16, 1, 652.

Research output: Contribution to journalArticle

Coroners and Medical Examiners
Medical Schools
Licensure
medical examiner
examination
2015
4 Citations (Scopus)

A central role for HLA-DR3 in anti-smith antibody responses and glomerulonephritis in a transgenic mouse model of spontaneous lupus

Chowdhary, V. R., Dai, C., Tilahun, A. Y., Hanson, J. A., Smart, M. K., Grande, J. P., Rajagopalan, G., Fu, S. M. & David, C. S., Nov 15 2015, In : Journal of Immunology. 195, 10, p. 4660-4667 8 p.

Research output: Contribution to journalArticle

HLA-DR3 Antigen
Glomerulonephritis
Transgenic Mice
Antibody Formation
Anti-Idiotypic Antibodies
5 Citations (Scopus)
Medical Schools
Curriculum
Curricula
Productivity
Medical Students
17 Citations (Scopus)

Cell Fusion Connects Oncogenesis with Tumor Evolution

Zhou, X., Merchak, K., Lee, W., Grande, J. P., Cascalho, M. & Platt, J. L., Jul 1 2015, In : American Journal of Pathology. 185, 7, p. 2049-2060 12 p., 2035.

Research output: Contribution to journalArticle

Cell Fusion
Carcinogenesis
Neoplasms
Chromosomal Instability
Cell Division
9 Citations (Scopus)
Heme Oxygenase (Decyclizing)
Heme Oxygenase-1
Up-Regulation
Carotid Arteries
Ligation
3 Citations (Scopus)

Metastatic renal cell carcinoma mimicking diverticulitis in a patient with chronic lymphocytic leukaemia

Hwang, S. M., Kuyava, J. M., Grande, J. P. & Swetz, K. M., Jan 7 2015, In : BMJ Case Reports. 2015, A45.

Research output: Contribution to journalArticle

Diverticulitis
B-Cell Chronic Lymphocytic Leukemia
Renal Cell Carcinoma
Kidney
Sigmoid Colon
2 Citations (Scopus)

Patient exposure in the basic science classroomenhances differential diagnosis formation and clinical decision-making

Peacock, J. G. & Grande, J. P., 2015, In : PeerJ. 2015, 2, e809.

Research output: Contribution to journalArticle

Pathology
decision making
Differential Diagnosis
Decision making
students
1 Citation (Scopus)

Specialty Choice Influences Medical Student Research and Productivity

Peacock, J. G. & Grande, J. P., Jun 1 2015, In : Medical Science Educator. 25, 2, p. 127-132 6 p.

Research output: Contribution to journalArticle

Medical Students
medical student
Biomedical Research
productivity
Medical Schools
3 Citations (Scopus)

The role of type I hypersensitivity reaction and IgE-mediated mast cell activation in acute interstitial nephritis

Zand, L., Monaghan, M., Griffin, B. R., Wagner, S. J., Criaci, I. M., Kamal, A., Raissian, Y., Grande, J. P., Lim, K. G. & Garovic, V. D., 2015, In : Clinical Nephrology. 84, 3, p. 138-144 7 p.

Research output: Contribution to journalArticle

Immediate Hypersensitivity
Interstitial Nephritis
Mast Cells
Immunoglobulin E
Interleukin-16
2014
6 Citations (Scopus)

Advances in the pathophysiology of preeclampsia and related podocyte injury

Weissgerber, T. L., Craici, I. M., Wagner, S. J., Grande, J. P. & Garovic, V. D., Aug 1 2014, In : Kidney International. 86, 2, p. 445 1 p.

Research output: Contribution to journalReview article

Puerperal Disorders
Animal Disease Models
Podocytes
Hydrogen Sulfide
Pre-Eclampsia
47 Citations (Scopus)

Advances in the pathophysiology of pre-eclampsia and related podocyte injury

Craici, I. M., Wagner, S. J., Weissgerber, T. L., Grande, J. P. & Garovic, V. D., 2014, In : Kidney International. 86, 2, p. 275-285 11 p.

Research output: Contribution to journalArticle

Podocytes
Pre-Eclampsia
Wounds and Injuries
Proteinuria
Mothers
1 Citation (Scopus)

A Novel Metric and Feedback Template Improves Differential Diagnosis Formation Capabilities in Pre-Clinical Medical Students.

Martin, B. A., Peacock, J. G., Warner, L. L., Wentworth, A. B., Adefusika, J. A., Bachman, M. J., Drozdowicz, L. B., Suresh, R. & Grande, J. P., Jun 1 2014, In : Medical Science Educator. 24, 2, p. 189-194 6 p.

Research output: Contribution to journalArticle

Medical Students
medical student
Aptitude
Differential Diagnosis
Medical Schools
8 Citations (Scopus)

A retrospective comparison of skin and renal direct immunofluorescence findings in patients with glomerulonephritis in adult Henoch-Schönlein purpura

Poterucha, T. J., Wetter, D. A., Grande, J. P., Gibson, L. E., Camilleri, M. J. & Lohse, C. M., 2014, In : Journal of Cutaneous Pathology. 41, 7, p. 582-587 6 p.

Research output: Contribution to journalArticle

Schoenlein-Henoch Purpura
Direct Fluorescent Antibody Technique
Glomerulonephritis
Kidney
Skin
14 Citations (Scopus)
Renin-Angiotensin System
Chronic Renal Insufficiency
Renal Artery Obstruction
Kidney
Angiotensin Receptor Antagonists
10 Citations (Scopus)

Heat stress induced cell death mechanisms in hepatocytes and hepatocellular carcinoma: In vitro and in vivo study

Thompson, S. M., Callstrom, M. R., Butters, K. A., Knudsen, B., Grande, J. P., Roberts, L. R. & Woodrum, D. A., 2014, In : Lasers in Surgery and Medicine. 46, 4, p. 290-301 12 p.

Research output: Contribution to journalArticle

Hepatocytes
Hepatocellular Carcinoma
Cell Death
Hot Temperature
Caspase 3
21 Citations (Scopus)

Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury

White, W. M., Garrett, A. T., Craici, I. M., Wagner, S. J., Fitz-Gibbon, P. D., Butters, K. A., Brost, B. C., Rose, C. H., Grande, J. P. & Garovic, V. D., Mar 24 2014, In : PLoS One. 9, 3, e92693.

Research output: Contribution to journalArticle

pre-eclampsia
Podocytes
Pre-Eclampsia
Postpartum Period
kidneys
24 Citations (Scopus)

Renal vein cytokine release as an index of renal parenchymal inflammation in chronic experimental renal artery stenosis

Eirin, A., Zhang, X., Zhu, X. Y., Tang, H., Jordan, K. L., Grande, J. P., Dietz, A. B., Lerman, A., Textor, S. C. & Lerman, L. O., Feb 2014, In : Nephrology Dialysis Transplantation. 29, 2, p. 274-282 9 p.

Research output: Contribution to journalArticle

Renal Artery Obstruction
Renal Veins
Cytokines
Inflammation
Kidney
12 Citations (Scopus)
Hepatocellular Carcinoma
Stem Cells
Hot Temperature
Animal Care Committees
Heat-Shock Response