Jorge Rakela, MD &ndash; Research Output

2018

Acute Liver Failure of Indeterminate Etiology: A Comprehensive Systematic Approach by An Expert Committee to Establish Causality

for the Acute Liver Failure Study Group, Jun 27 2018, (Accepted/In press) In : American Journal of Gastroenterology. p. 1-10 10 p.

Research output: Contribution to journal › Article

Acute Liver Failure

Acetaminophen

Causality

Chemical and Drug Induced Liver Injury

Metagenomics

7 Citations (Scopus)

Pilot evaluation of PD-1 inhibition in metastatic cancer patients with a history of liver transplantation: The Mayo Clinic experience

DeLeon, T. T., Salomao, M. A., Aqel, B. A., Sonbol, M. B., Yokoda, R. T., Ali, A. H., Moss, A. A., Mathur, A., Chascsa, D. M., Rakela, J., Bryce, A. H. & Borad, M. J., Dec 1 2018, In : Journal of Gastrointestinal Oncology. 9, 6, p. 1054-1062 9 p.

Research output: Contribution to journal › Article

Liver Transplantation

Neoplasms

Proteins

Allografts

Ligands

2017

Improving Hepatitis Vaccination Series Completion in Patients Awaiting Liver Transplantation

Perez, S. T., Arring, N. M., Vargas, H. E., Corbett, B. M., Ehler, S., Beck, G. L., Temkit, M., Aqel, B. A. & Rakela, J., 2017, (Accepted/In press) In : Journal for Nurse Practitioners.

Research output: Contribution to journal › Article

Liver Transplantation

Hepatitis

Vaccination

Vaccines

Combined Vaccines

Right hepatic lobe resection and thrombocytopenia

Adike, A., Rakela, J., Czaplicki, C., Moss, A. & Carey, E., Jan 1 2017, In : Annals of Hepatology. 16, 1, p. 10-11 2 p.

Research output: Contribution to journal › Article

Hepatectomy

Thrombocytopenia

Tissue and Organ Procurement

Blood Platelets

Liver

Thomas E. Starzl, M.D., Ph.D. (1926-2017)

Rakela, J. & Fung, J. J., 2017, (Accepted/In press) In : Hepatology.

Research output: Contribution to journal › Article

2016

14 Citations (Scopus)

Acute liver failure associated with Garcinia cambogia use

Corey, R., Werner, K. T., Singer, A., Moss, A., Smith, M., Noelting, J. & Rakela, J., Jan 1 2016, In : Annals of Hepatology. 15, 1, p. 123-126 4 p.

Research output: Contribution to journal › Article

Garcinia cambogia

Acute Liver Failure

Liver Failure

Dietary Supplements

Liver Transplantation

32 Citations (Scopus)

Clinical Features and Outcomes of Complementary and Alternative Medicine Induced Acute Liver Failure and Injury

Hillman, L., Gottfried, M., Whitsett, M., Rakela, J., Schilsky, M., Lee, W. M. & Ganger, D., Apr 5 2016, (Accepted/In press) In : American Journal of Gastroenterology.

Research output: Contribution to journal › Article

Acute Liver Failure

Complementary Therapies

Wounds and Injuries

Chemical and Drug Induced Liver Injury

Prescriptions

3 Citations (Scopus)

Hepatitis E virus serum antibodies and RNA prevalence in patients evaluated for heart and kidney transplantation

Unzueta, A., Valdez, R., Chang, Y. H. H., Desmarteau, Y. M., Heilman, R. L., Scott, R. L., Douglas, D. D. & Rakela, J., Jan 1 2016, In : Annals of Hepatology. 15, 1, p. 33-40 8 p.

Research output: Contribution to journal › Article

Hepatitis E virus

Heart Transplantation

Kidney Transplantation

RNA

Antibodies

16 Citations (Scopus)

microRNA changes in liver tissue associated with fibrosis progression in patients with hepatitis C

Van Keuren-Jensen, K. R., Malenica, I., Courtright, A. L., Ghaffari, L. T., Starr, A. P., Metpally, R. P., Beecroft, T. A., Carlson, E. W. J., Kiefer, J. A., Pockros, P. J. & Rakela, J., Mar 1 2016, In : Liver International. 36, 3, p. 334-343 10 p.

Research output: Contribution to journal › Article

Hepatitis C

MicroRNAs

Fibrosis

Liver

Liver Cirrhosis

2015

27 Citations (Scopus)

Progenitor cell markers predict outcome of patients with hepatocellular carcinoma beyond Milan criteria undergoing liver transplantation

Miltiadous, O., Sia, D., Hoshida, Y., Fiel, M. I., Harrington, A. N., Thung, S. N., Tan, P. S., Dong, H., Revill, K., Chang, C. Y., Roayaie, S., Byrne, T. J., Mazzaferro, V., Rakela, J., Florman, S., Schwartz, M. & Llovet, J. M., Dec 1 2015, In : Journal of Hepatology. 63, 6, p. 1368-1377 10 p.

Research output: Contribution to journal › Article

Liver Transplantation

Hepatocellular Carcinoma

Stem Cells

Keratin-19

Recurrence

44 Citations (Scopus)

Relationship between sarcopenia, six-minute walk distance and health-related quality of life in liver transplant candidates

Yadav, A., Chang, Y. H., Carpenter, S., Silva, A. C., Rakela, J., Aqel, B. A., Byrne, T. J., Douglas, D. D., Vargas, H. E. & Carey, E. J., Feb 1 2015, In : Clinical Transplantation. 29, 2, p. 134-141 8 p.

Research output: Contribution to journal › Article

Sarcopenia

Quality of Life

Transplants

Liver

Skeletal Muscle

2014

42 Citations (Scopus)

Cellular therapy for liver disease

Huebert, R. C. & Rakela, J., 2014, In : Mayo Clinic Proceedings. 89, 3, p. 414-424 11 p.

Research output: Contribution to journal › Article

Liver Diseases

Stem Cells

Regenerative Medicine

Cell- and Tissue-Based Therapy

Transplants

4 Citations (Scopus)

Complementary and alternative medicine: Risks and special considerations in pretransplant and posttransplant patients

Corey, R. L. & Rakela, J., 2014, In : Nutrition in Clinical Practice. 29, 3, p. 322-331 10 p.

Research output: Contribution to journal › Article

Complementary Therapies

Dietary Supplements

Insurance Benefits

Transplantation

Transplants

15 Citations (Scopus)

Hepatitis e infection in liver transplant recipients

Unzueta, A. & Rakela, J., 2014, In : Liver Transplantation. 20, 1, p. 15-24 10 p.

Research output: Contribution to journal › Article

Hepatitis E virus

Hepatitis

Virus Diseases

Liver

Infection

6 Citations (Scopus)

Magnetic resonance elastography can discriminate normal vs. abnormal liver biopsy in candidates for live liver donation

Gallegos-Orozco, J. F., Silva, A. C., Batheja, M. J., Chang, Y. H., Hansen, K. L., Lam-Himlin, D., De Petris, G., Aqel, B. A., Byrne, T. J., Carey, E. J., Douglas, D. D., Mulligan, D. C., Silva, A. M., Rakela, J. & Vargas, H. E., Dec 2 2014, (Accepted/In press) In : Abdominal Imaging.

Research output: Contribution to journal › Article

Elasticity Imaging Techniques

Biopsy

Liver

ROC Curve

Area Under Curve

19 Citations (Scopus)

Vitamin D deficiency, parathyroid hormone levels, and bone disease among patients with end-stage liver disease and normal serum creatinine awaiting liver transplantation

Corey, R. L., Whitaker, M. D., Crowell, M. D., Keddis, M., Aqel, B., Balan, V., Byrne, T., Carey, E., Douglas, D. D., Harrison, M. E., Vargas, H. E. & Rakela, J., 2014, In : Clinical Transplantation. 28, 5, p. 579-584 6 p.

Research output: Contribution to journal › Article

End Stage Liver Disease

Vitamin D Deficiency

Bone Diseases

Parathyroid Hormone

Liver Transplantation

2013

1 Citation (Scopus)

Impact of computerized provider order entry on hospital medication errors

Roberts, D. L., Noble, B. N., Wright, M. J., Nelson, E. A., Shaft, J. D. & Rakela, J., Mar 2013, In : Journal of Clinical Outcomes Management. 20, 3, p. 109-115 7 p.

Research output: Contribution to journal › Article

Medical Order Entry Systems

Medication Errors

Drug-Related Side Effects and Adverse Reactions

Teaching Hospitals

Heparin

70 Citations (Scopus)

Portal vein thrombosis in patients with end stage liver disease awaiting liver transplantation: Outcome of anticoagulation

Werner, K. T., Sando, S., Carey, E. J., Vargas, H. E., Byrne, T. J., Douglas, D. D., Harrison, M. E., Rakela, J. & Aqel, B. A., Jun 2013, In : Digestive Diseases and Sciences. 58, 6, p. 1776-1780 5 p.

Research output: Contribution to journal › Article

End Stage Liver Disease

Portal Vein

Liver Transplantation

Thrombosis

Liver Cirrhosis

2012

18 Citations (Scopus)

Evidence for liver injury in the setting of obstructive sleep apnea

Byrne, T. J., Parish, J. M., Somers, V., Aqel, B. A. & Rakela, J., Mar 2012, In : Annals of Hepatology. 11, 2, p. 228-231 4 p.

Research output: Contribution to journal › Article

Obstructive Sleep Apnea

Liver

Wounds and Injuries

Alanine Transaminase

Obesity

2011

26 Citations (Scopus)

Monoclonal gammopathy of undetermined significance does not affect outcomes in patients undergoing solid organ transplants

Jimenez-Zepeda, V. H., Heilman, R. L., Engel, R. A., Carey, E. J., Freeman, C., Rakela, J., Mulligan, D. C., Fonseca, R. & Stewart, A. K., Sep 15 2011, In : Transplantation. 92, 5, p. 570-574 5 p.

Research output: Contribution to journal › Article

Monoclonal Gammopathy of Undetermined Significance

Transplants

Lymphoproliferative Disorders

Multiple Myeloma

Paraproteinemias

20 Citations (Scopus)

Tratamiento exitoso de hepatitis autoinmune y síndrome de Evans con rituximab

Translated title of the contribution: Successful rituximab therapy in refractory autoimmune hepatitis and Evans syndromeCarey, E. J., Somaratne, K. & Rakela, J., Nov 2011, In : Revista Medica de Chile. 139, 11, p. 1484-1487 4 p.

Research output: Contribution to journal › Article

Autoimmune Hepatitis

Transaminases

Mycophenolic Acid

Liver

Azathioprine

2010

5 Citations (Scopus)

Gene therapy and enhancement for diabetes (and other diseases): The multiplicity of considerations

Bertolaso, M., Olsson, J., Picardi, A. & Rakela, J., Oct 2010, In : Diabetes/Metabolism Research and Reviews. 26, 7, p. 520-524 5 p.

Research output: Contribution to journal › Article

Genetic Therapy

Literature

Mutation

Human Genome

Biotechnology

2 Citations (Scopus)

Recurrencia de la enfermedad hepática primaria después del trasplante hepático

Translated title of the contribution: Liver disease recurrence after liver transplantationRakela, J., Apr 2010, In : Revista Medica de Chile. 138, 4, p. 504-510 7 p.

Research output: Contribution to journal › Article

Liver Transplantation

Liver Diseases

Recurrence

Liver

Antiviral Agents

43 Citations (Scopus)

Safety studies on intrahepatic or intratumoral injection of oncolytic vesicular stomatitis virus expressing interferon-β in rodents and nonhuman primates

Jenks, N., Myers, R., Greiner, S. M., Thompson, J., Mader, E. K., Greenslade, A., Griesmann, G. E., Federspiel, M. J., Rakela, J., Borad, M. J., Vile, R. G., Barber, G. N., Meier, T. D., Blanco, M. C., Carlson, S. K., Russell, S. J. & Peng, K-W., Apr 1 2010, In : Human Gene Therapy. 21, 4, p. 451-462 12 p.

Research output: Contribution to journal › Article

Vesicular Stomatitis

Interferons

Primates

Rodentia

Viruses

121 Citations (Scopus)

Six-minute walk distance predicts mortality in liver transplant candidates

Carey, E. J., Steidley, D. E., Aqel, B. A., Byrne, T. J., Mekeel, K. L., Rakela, J., Vargas, H. E. & Douglas, D. D., Dec 2010, In : Liver Transplantation. 16, 12, p. 1373-1378 6 p.

Research output: Contribution to journal › Article

End Stage Liver Disease

Liver Transplantation

Transplants

Mortality

Liver

9 Citations (Scopus)

Treatment of hepatitis C in renal transplantation candidates: A single-center experience

Werner, T., Aqel, B., Balan, V., Byrne, T., Carey, E., Douglas, D., Heilman, R. L., Rakela, J., Mekeel, K., Reddy, K. S. & Vargas, H. E., Aug 27 2010, In : Transplantation. 90, 4, p. 407-411 5 p.

Research output: Contribution to journal › Article

Hepatitis C

Kidney Transplantation

Hepacivirus

Interferons

Therapeutics

2009

A message from the editors: Thank you

Rakela, J. & Fung, J. F., Dec 2009, In : Liver Transplantation. 15, 12, p. 1657 1 p.

Research output: Contribution to journal › Article

Journal Impact Factor

International Cooperation

Liver Transplantation

Cooperative Behavior

Biomedical Research

4 Citations (Scopus)

An unusual occurrence of giant cell hepatitis

Singh, V., Rudraraju, M., Carey, E. J., Byrne, T. J., Douglas, D. D., Rakela, J. & Vargas, H. E., Dec 2009, In : Liver Transplantation. 15, 12, p. 1888-1890 3 p.

Research output: Contribution to journal › Article

Autoimmune Hepatitis

Giant Cells

Immunosuppressive Agents

Combination Drug Therapy

Liver Transplantation

72 Citations (Scopus)

Natural history of post-liver transplantation hepatitis C: A review of factors that may influence its course

Gallegos-Orozco, J. F., Yosephy, A., Noble, B., Aqel, B. A., Byrne, T. J., Carey, E. J., Douglas, D. D., Mulligan, D., Moss, A., De Petris, G., Williams, J. W., Rakela, J. & Vargas, H. E., Dec 2009, In : Liver Transplantation. 15, 12, p. 1872-1881 10 p.

Research output: Contribution to journal › Article

Hepatitis C

Natural History

Liver Transplantation

Survival

End Stage Liver Disease

15 Citations (Scopus)

Severe hepatotoxicity caused by a methasteron-containing performance-enhancing supplement

Singh, V., Rudraraju, M., Carey, E. J., Byrne, T. J., Vargas, H. E., Williams, J. E., Balan, V., Douglas, D. D. & Rakela, J., Mar 2009, In : Journal of Clinical Gastroenterology. 43, 3, p. 287 1 p.

Research output: Contribution to journal › Article

Chemical and Drug Induced Liver Injury

Anabolic Agents

Cholestasis

Dietary Supplements

Bilirubin

2008

1 Citation (Scopus)

Conflict of interest policy

Lindor, K., Rakela, J. & Fung, J., Jan 2008, In : Hepatology. 47, 1, p. 1 1 p.

Research output: Contribution to journal › Article

Editorial Policies

Conflict of Interest

Conflict of interest policy

Lindor, K., Rakela, J. & Fung, J., Jan 2008, In : Liver Transplantation. 14, 1, p. 1 1 p.

Research output: Contribution to journal › Article

Conflict of Interest

1 Citation (Scopus)

Erythropoietin does not increase the frequency of thromboembolic events or hepatocellular carcinoma in hepatitis C patients treated with combination antiviral therapy

Gallegos-Orozco, J. F., Werner, K. T., Rosati, M., Byrne, T. J., Balan, V., Vargas, H. E. & Rakela, J., Aug 2008, In : American Journal of Gastroenterology. 103, 8, p. 2161-2162 2 p.

Research output: Contribution to journal › Article

41 Citations (Scopus)

Hepatic steatosis in chronic hepatitis C: Baseline host and viral characteristics and influence on response to therapy with peginterferon α-2a plus ribavirin

Reddy, K. R., Govindarajan, S., Marcellin, P., Bernstein, D., Dienstag, J. L., Bodenheimer, H., Rakela, J., Messinger, D., Schmidt, G., Ackrill, A. & Hadziyannis, S. J., Feb 2008, In : Journal of Viral Hepatitis. 15, 2, p. 129-136 8 p.

Research output: Contribution to journal › Article

Ribavirin

Chronic Hepatitis C

Liver

Hepacivirus

Genotype

22 Citations (Scopus)

Inpatient admissions for drug-induced liver injury: Results from a single center

Carey, E. J., Vargas, H. E., Douglas, D. D., Balan, V., Byrne, T. J., Harrison, M. E. & Rakela, J., Jul 2008, In : Digestive Diseases and Sciences. 53, 7, p. 1977-1982 6 p.

Research output: Contribution to journal › Article

Chemical and Drug Induced Liver Injury

Inpatients

Acetaminophen

International Classification of Diseases

Liver

10 Citations (Scopus)

Living donor liver transplantation in polycystic liver disease

Mekeel, K. L., Moss, A. A., Reddy, K. S., Douglas, D. D., Vargas, H. E., Carey, E. J., Byrne, T. J., Harrison, M. E., Rakela, J. & Mulligan, D. C., May 2008, In : Liver Transplantation. 14, 5, p. 680-683 4 p.

Research output: Contribution to journal › Article

Living Donors

Liver Transplantation

Venae Cavae

Hepatomegaly

Hepatectomy

55 Citations (Scopus)

Long-term outcome of human leukocyte antigen mismatching in liver transplantation: Results of the National institute of diabetes and digestive and kidney diseases liver transplantation database

Balan, V., Ruppert, K., Demetris, A. J., Ledneva, T., Duquesnoy, R. J., Detre, K. M., Wei, Y. L., Rakela, J., Schafer, D. F., Roberts, J. P., Everhart, J. E. & Wiesner, R. H., Sep 2008, In : Hepatology. 48, 3, p. 878-888 11 p.

Research output: Contribution to journal › Article

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)

HLA Antigens

Liver Transplantation

Databases

Recurrence

18 Citations (Scopus)

Persistence of hepatitis C virus in peripheral blood mononuclear cells of sustained viral responders to pegylated interferon and ribavirin therapy

Gallegos-Orozco, J. F., Rakela, J., Rosati, M. J., Vargas, H. E. & Balan, V., Sep 2008, In : Digestive Diseases and Sciences. 53, 9, p. 2564-2568 5 p.

Research output: Contribution to journal › Article

Ribavirin

Hepacivirus

Interferons

Blood Cells

Viral RNA

2007

19 Citations (Scopus)

Liver transplantation in China

Rakela, J. & Fung, J. J., Feb 2007, In : Liver Transplantation. 13, 2, p. 182 1 p.

Research output: Contribution to journal › Article

Liver Transplantation

China

21 Citations (Scopus)

Pegylated interferon and ribavirin failures: Is retreatment an option?

Cheruvattath, R., Rosati, M. J., Gautam, M., Vargas, H. E., Rakela, J. & Balan, V., Mar 2007, In : Digestive Diseases and Sciences. 52, 3, p. 732-736 5 p.

Research output: Contribution to journal › Article

Retreatment

Ribavirin

Interferons

Therapeutics

Chronic Hepatitis C

2006

13 Citations (Scopus)

Liver transplantation in the MELD era: A single-center experience

Sachdev, M., Hernandez, J. L., Sharma, P., Douglas, D. D., Byrne, T., Harrison, M. E., Mulligan, D., Moss, A., Reddy, K. S., Vargas, H. E., Rakela, J. & Balan, V., Jun 2006, In : Digestive Diseases and Sciences. 51, 6, p. 1070-1078 9 p.

Research output: Contribution to journal › Article

Liver Transplantation

Liver Diseases

Transplantation

Tissue Donors

Hepatocellular Carcinoma

46 Citations (Scopus)

Living donor liver transplantation for hepatitis C-related cirrhosis: No difference in histological recurrence when compared to deceased donor liver transplantation recipients

Guo, L., Orrego, M., Rodriguez-Luna, H., Balan, V., Byrne, T., Chopra, K., Douglas, D. D., Harrison, E., Moss, A., Reddy, K. S., Williams, J. W., Rakela, J., Mulligan, D. & Vargas, H. E., Apr 2006, In : Liver Transplantation. 12, 4, p. 560-565 6 p.

Research output: Contribution to journal › Article

Living Donors

Hepatitis C

Liver Transplantation

Fibrosis

Tissue Donors

6 Citations (Scopus)

Selection of different 5′ untranslated region hepatitis C virus variants during post-transfusion and post-transplantation infection

Gallegos-Orozco, J. F., Arenas, J. I., Vargas, H. E., Kibler, K. V., Wilkinson, J. K., Nowicki, M., Radkowski, M., Nasseri, J., Rakela, J. & Laskus, T., Jul 2006, In : Journal of Viral Hepatitis. 13, 7, p. 489-498 10 p.

Research output: Contribution to journal › Article

5' Untranslated Regions

Hepacivirus

Transplantation

Infection

Hep G2 Cells

6 Citations (Scopus)

Successful treatment with novel triple drug combination consisting of interferon-γ, interferon alfacon-1, and ribavirin in a nonresponder HCV patient to pegylated interferon therapy

Balan, V., Rosati, M. J., Anderson, M. H. & Rakela, J., May 2006, In : Digestive Diseases and Sciences. 51, 5, p. 956-959 4 p.

Research output: Contribution to journal › Article

Ribavirin

Drug Combinations

Interferons

Therapeutics

Hepatitis C

2005

A message from the incoming editors of Liver Transplantation

Rakela, J. & Fung, J., Jan 2005, In : Liver Transplantation. 11, 1, p. 1-2 2 p.

Research output: Contribution to journal › Article

Liver Transplantation

5 Citations (Scopus)

Artificial neural network and tissue genotyping of hepatocellular carcinoma in liver-transplant recipients: Prediction of recurrence

Rodriguez-Luna, H., Vargas, H. E., Byrne, T. & Rakela, J., Jun 27 2005, In : Transplantation. 79, 12, p. 1737-1740 4 p.

Research output: Contribution to journal › Article

Hepatocellular Carcinoma

Guanosine Triphosphate

Recurrence

Liver

Liver Transplantation

12 Citations (Scopus)

Differential display analysis of gene expression in brains from hepatitis C-infected patients

Adair, D. M., Radkowski, M., Jablonska, J., Pawelczyk, A., Wilkinson, J., Rakela, J. & Laskus, T., Oct 2005, In : AIDS. 19, SUPPL. 3

Research output: Contribution to journal › Article

Hepatitis C

Hepacivirus

Gene Expression

Brain

Virus Diseases

89 Citations (Scopus)

Emerging evidence of hepatitis C virus neuroinvasion

Laskus, T., Radkowski, M., Adair, D. M., Wilkinson, J., Scheck, A. C. & Rakela, J., Oct 2005, In : AIDS. 19, SUPPL. 3

Research output: Contribution to journal › Article

Hepacivirus

Virus Diseases

HIV-1

Brain

Macrophages

9 Citations (Scopus)

Hepatic B-cell non-Hodgkin's lymphoma of MALT type in the liver explant of a patient with chronic hepatitis C infection

Orrego, M., Guo, L., Reeder, C., De Petris, G., Balan, V., Douglas, D. D., Byrne, T., Harrison, E., Mulligan, D., Rodriguez-Luna, H., Moss, A., Reddy, K. S., Rakela, J. & Vargas, H. E., Jul 2005, In : Liver Transplantation. 11, 7, p. 796-799 4 p.

Research output: Contribution to journal › Article

B-Cell Lymphoma

Chronic Hepatitis C

Non-Hodgkin's Lymphoma

Hepatocytes

Marginal Zone B-Cell Lymphoma

33 Citations (Scopus)

Lack of association of common cystic fibrosis transmembrane conductance regulator gene mutations with primary sclerosing cholangitis

Gallegos-Orozco, J. F., Yurk, C. E., Wang, N., Rakela, J., Charlton, M. R., Cutting, G. R. & Balan, V., Apr 2005, In : American Journal of Gastroenterology. 100, 4, p. 874-878 5 p.

Research output: Contribution to journal › Article

Cystic Fibrosis Transmembrane Conductance Regulator

Sclerosing Cholangitis

Regulator Genes

Cystic Fibrosis

Mutation