• 10395 Citations
  • 56 Scopus h-Index
1989 …2019
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Research Output 1989 2019

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Article
2019
4 Citations (Scopus)

Family History Associates With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases

Samadder, N. J., Valentine, J. F., Guthery, S., Singh, H., Bernstein, C. N., Leighton, J. A., Wan, Y., Wong, J., Boucher, K., Pappas, L., Rowe, K., Burt, R. W., Curtin, K. & Smith, K. R., Jan 1 2019, In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Colorectal Neoplasms
Incidence
Population Surveillance
Databases
1 Citation (Scopus)

Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients with Inflammatory Bowel Disease

Wang, M. H., Friton, J. J., Raffals, L. E. H., Leighton, J. A., Pasha, S. F., Picco, M. F., Cushing, K. C., Monroe, K., Nix, B. D., Newberry, R. D. & Faubion, W. A., Aug 14 2019, In : Journal of Crohn's and Colitis. 13, 8, p. 1036-1043 8 p., jjz017.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Tumor Necrosis Factor-alpha
Genetic Loci
Odds Ratio
Therapeutics
1 Citation (Scopus)

The Clinician's Guide to Suspected Small Bowel Bleeding

Kuo, J. R., Pasha, S. F. & Leighton, J. A., Apr 1 2019, In : The American Journal of Gastroenterology. 114, 4, p. 591-598 8 p.

Research output: Contribution to journalArticle

Hemorrhage
Capsule Endoscopy
Equipment and Supplies
2018
2 Citations (Scopus)

Impact of feedback on adenoma detection rates: Outcomes of quality improvement program

Gurudu, S. R., Boroff, E. S., Crowell, M. D., Atia, M., Umar, S. B., Leighton, J. A., Faigel, D. O. & Ramirez, F. C., Mar 1 2018, In : Journal of Gastroenterology and Hepatology (Australia). 33, 3, p. 645-649 5 p.

Research output: Contribution to journalArticle

Quality Improvement
Adenoma
Colonoscopy
Endoscopy
Outcome Assessment (Health Care)
4 Citations (Scopus)

Is the level of cleanliness using segmental boston bowel preparation scale associated with a higher adenoma detection rate?

Adike, A., Buras, M. R., Gurudu, S. R., Leighton, J. A., Faigel, D. O., Ruff, K. C., Umar, S. B. & Ramirez, F. C., Mar 5 2018, In : Annals of Gastroenterology. 31, 2, p. 217-223 7 p.

Research output: Contribution to journalArticle

Adenoma
Polyps
Odds Ratio
Confidence Intervals
Colonoscopy
4 Citations (Scopus)

Utility of video capsule endoscopy for longitudinal monitoring of Crohn's disease activity in the small bowel: a prospective study

Melmed, G. Y., Dubinsky, M. C., Rubin, D. T., Fleisher, M., Pasha, S. F., Sakuraba, A., Tiongco, F., Shafran, I., Fernandez-Urien, I., Rosa, B., Papageorgiou, N. P. & Leighton, J. A., Jan 1 2018, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Capsule Endoscopy
Crohn Disease
Prospective Studies
Leukocyte L1 Antigen Complex
Blood Sedimentation
2017
19 Citations (Scopus)

Comparing diagnostic yield of a novel pan-enteric video capsule endoscope with ileocolonoscopy in patients with active Crohn's disease: a feasibility study

Leighton, J. A., Helper, D. J., Gralnek, I. M., Dotan, I., Fernandez-Urien, I., Lahat, A., Malik, P., Mullin, G. E. & Rosa, B., Jan 1 2017, In : Gastrointestinal Endoscopy. 85, 1, p. 196-205.e1

Research output: Contribution to journalArticle

Capsule Endoscopes
Feasibility Studies
Crohn Disease
Colon
Capsules
1 Citation (Scopus)

Duodenal gangliocytic paraganglioma: Endoscopy, sonography and F-18 FDG PET/CT imaging

Yang, M., Leighton, J. A., Faigel, D. O. & Katariya, N. N., 2017, (Accepted/In press) In : Digestive and Liver Disease.

Research output: Contribution to journalArticle

Paraganglioma
Endoscopy
Ultrasonography
2 Citations (Scopus)

Evidence-based guide on capsule endoscopy for small bowel bleeding

Pasha, S. F. & Leighton, J. A., Feb 1 2017, In : Gastroenterology and Hepatology. 13, 2, p. 88-93 6 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Hemorrhage
Capsules
Triage
Routine Diagnostic Tests
5 Citations (Scopus)

Identification of antibody against SNRPB, small nuclear ribonucleoprotein-associated proteins B and B', as an autoantibody marker in Crohn's disease using an immunoproteomics approach

Wang, H., Demirkan, G., Bian, X., Wallstrom, G., Barker, K., Karthikeyan, K., Tang, Y., Pasha, S. F., Leighton, J. A., Qiu, J. & LaBaer, J., 2017, In : Journal of Crohn's and Colitis. 11, 7, p. 848-856 9 p.

Research output: Contribution to journalArticle

snRNP Core Proteins
Crohn Disease
Autoantibodies
Antibodies
Protein Array Analysis
4 Citations (Scopus)

Optimizing the quality of endoscopy in inflammatory bowel disease: focus on surveillance and management of colorectal dysplasia using interactive image- and video-based teaching

Optimizing Quality of Endoscopy in IBD Group, Dec 1 2017, In : Gastrointestinal Endoscopy. 86, 6, p. 1107-1117.e1

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Endoscopy
Teaching
Gastrointestinal Endoscopy
Terminology
8 Citations (Scopus)

The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer

Uribe, D. J., Mandell, E. K., Watson, A., Martinez, J. D., Leighton, J. A., Ghosh, S. & Rothlin, C. V., Jul 1 2017, In : PLoS One. 12, 7, e0179979.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
colorectal neoplasms
tyrosine
Colorectal Neoplasms
phosphotransferases (kinases)
2016

Response to Perez-Cuadrado Robles

Gerson, L. B., Fidler, J. L., Cave, D. R. & Leighton, J. A., Feb 1 2016, In : American Journal of Gastroenterology. 111, 2, p. 294-295 2 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Gastrointestinal Hemorrhage
X Ray Computed Tomography
Colonoscopy
Disease Management

The Elusive Bleeder: Tips for Avoiding a Wild Goose Chase

Pasha, S. F. & Leighton, J. A., Feb 9 2016, (Accepted/In press) In : American Journal of Gastroenterology.

Research output: Contribution to journalArticle

Gastrointestinal Hemorrhage
X Ray Computed Tomography
Symptom Assessment
Gastrointestinal Diseases
Disease Management
2015
180 Citations (Scopus)

ACG Clinical Guideline: Diagnosis and Management of Small Bowel Bleeding

Gerson, L. B., Fidler, J. L., Cave, D. R. & Leighton, J. A., Sep 10 2015, In : American Journal of Gastroenterology. 110, 9, p. 1265-1287 23 p.

Research output: Contribution to journalArticle

Guidelines
Hemorrhage
Capsule Endoscopy
Colonoscopy
Endoscopy
14 Citations (Scopus)

Alternatives to Incomplete Colonoscopy

Villa, N. A., Pannala, R., Pasha, S. F. & Leighton, J. A., Nov 23 2015, In : Current Gastroenterology Reports. 17, 11, 43.

Research output: Contribution to journalArticle

Colonoscopy
Polyps
Colon
Colonoscopes
Patient Positioning
14 Citations (Scopus)

Double-balloon enteroscopy in Crohn's disease: Findings and impact on management in a multicenter retrospective study

Rahman, A., Ross, A., Leighton, J. A., Schembre, D., Gerson, L., Lo, S. K., Waxman, I., Dye, C. & Semrad, C., Jul 1 2015, In : Gastrointestinal Endoscopy. 82, 1, p. 102-107 6 p.

Research output: Contribution to journalArticle

Double-Balloon Enteroscopy
Crohn Disease
Multicenter Studies
Retrospective Studies
Capsule Endoscopy
14 Citations (Scopus)

Nonneoplastic polypectomy during screening colonoscopy: The impact on polyp detection rate, adenoma detection rate, and overall cost

Atia, M. A., Patel, N. C., Ratuapli, S. K., Boroff, E. S., Crowell, M. D., Gurudu, S. R., Faigel, D. O., Leighton, J. A. & Ramirez, F. C., Aug 1 2015, In : Gastrointestinal Endoscopy. 82, 2, p. 370-375.e1

Research output: Contribution to journalArticle

Colonoscopy
Polyps
Adenoma
Costs and Cost Analysis
Tertiary Care Centers

Preface

Kozarek, R. & Leighton, J. A., Jan 1 2015, In : Unknown Journal. p. v-vi

Research output: Contribution to journalArticle

2 Citations (Scopus)

The role of capsule endoscopy in evaluating both suspected and known Crohn's disease

Boroff, E. S. & Leighton, J. A., Jan 1 2015, In : Techniques in Gastrointestinal Endoscopy. 17, 1, p. 5-11 7 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Crohn Disease
Inflammatory Bowel Diseases
Capsule Endoscopes
Capsules
1 Citation (Scopus)

Using Hybrid Change Strategies to Improve the Patient Experience in Outpatient Specialty Care

Miranda, R., Glenn, S. W., Leighton, J. A., Pasha, S. F., Gurudu, S. R., Teaford, H. G., Mertz, L. E., Lee, H. R., Mamby, S. A., Johnson, M. F. & Raghu, T. S., Sep 1 2015, In : Journal of Healthcare Management. 60, 5, p. 363-376 14 p.

Research output: Contribution to journalArticle

Ambulatory Care
Government Regulation
Moving and Lifting Patients
Electronic Health Records
Medical Records
2014

Advances in capsule endoscopy in the diagnosis of Crohn's disease

Leighton, J. A., 2014, In : Gastroenterology and Hepatology. 10, 5, p. 319-321 3 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Crohn Disease
38 Citations (Scopus)

Capsule Endoscopy Is Superior to Small-bowel Follow-through and Equivalent to Ileocolonoscopy in Suspected Crohn's Disease

Leighton, J. A., Gralnek, I. M., Cohen, S. A., Toth, E., Cave, D. R., Wolf, D. C., Mullin, G. E., Ketover, S. R., Legnani, P. E., Seidman, E. G., Crowell, M. D., Bergwerk, A. J., Peled, R. & Eliakim, R., 2014, In : Clinical Gastroenterology and Hepatology. 12, 4, p. 609-615 7 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Crohn Disease
Inflammation
Intestinal Mucosa
Ileum
15 Citations (Scopus)

Evaluation and management of small-bowel tumors in the era of deep enteroscopy

Islam, R. S., Leighton, J. A. & Pasha, S. F., 2014, In : Gastrointestinal Endoscopy. 79, 5, p. 732-740 9 p.

Research output: Contribution to journalArticle

Ileal Neoplasms
Jejunal Neoplasms
Duodenal Neoplasms
Double-Balloon Enteroscopy
Capsule Endoscopy
3 Citations (Scopus)

Postcolonoscopy followup recommendations: Comparison with and without use of polyp pathology

Ratuapli, S. K., Gurudu, S. R., Atia, M. A., Crowell, M. D., Umar, S. B., Harrison, M. E., Leighton, J. A. & Ramirez, F. C., 2014, In : Diagnostic and Therapeutic Endoscopy. 2014, 683491.

Research output: Contribution to journalArticle

Colonoscopy
Polyps
Pathology
Adenomatous Polyps
Advisory Committees
14 Citations (Scopus)

Tyro3, Axl, and Mertk receptor signaling in inflammatory bowel disease and colitis-associated cancer

Rothlin, C. V., Leighton, J. A. & Ghosh, S., 2014, In : Inflammatory Bowel Diseases. 20, 8, p. 1472-1480 9 p.

Research output: Contribution to journalArticle

Colitis
Inflammatory Bowel Diseases
Inflammation
Ligands
Cytophagocytosis
2013
17 Citations (Scopus)

A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope

Choi, E. H., Mergener, K., Semrad, C., Fisher, L., Cave, D. R., Dodig, M., Burke, C., Leighton, J. A., Kastenberg, D., Simpson, P., Sul, J., Bhattacharya, K., Charles, R., Gerson, L., Weber, L., Eisen, G., Reidel, W., Vargo, J. J., Wakim-Fleming, J. & Lo, S. K., Aug 2013, In : Gastrointestinal Endoscopy. 78, 2, p. 325-332 8 p.

Research output: Contribution to journalArticle

Capsule Endoscopes
Capsules
Hemorrhage
Bleeding Time
Human Body
25 Citations (Scopus)

Capsule endoscopy in patients with implantable electromedical devices is safe

Harris, L. A., Hansel, S. L., Rajan, E., Srivathsan, K., Rea, R., Crowell, M. D., Fleischer, D. E., Pasha, S. F., Gurudu, S. R., Heigh, R. I., Shiff, A. D., Post, J. K. & Leighton, J. A., 2013, In : Gastroenterology Research and Practice. 2013, 959234.

Research output: Contribution to journalArticle

Capsule Endoscopy
Capsules
Equipment and Supplies
Celiac Disease
Crohn Disease
8 Citations (Scopus)

Downregulation of hematopoietic MUC1 during Experimental colitis increases tumor-promoting myeloid-derived suppressor cells

Poh, T. W., Madsen, C. S., Gorman, J. E., Marler, R. J., Leighton, J. A., Cohen, P. A. & Gendler, S. J., Sep 15 2013, In : Clinical Cancer Research. 19, 18, p. 5039-5052 14 p.

Research output: Contribution to journalArticle

Colitis
Down-Regulation
Neoplasms
Inflammatory Bowel Diseases
Colon
10 Citations (Scopus)

Endoscopic Techniques for Small Bowel Imaging

Pasha, S. F. & Leighton, J. A., Jan 2013, In : Radiologic Clinics of North America. 51, 1, p. 177-187 11 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Therapeutics
6 Citations (Scopus)

Impact of fentanyl in lieu of meperidine on endoscopy unit efficiency: A prospective comparative study in patients undergoing EGD

Dzeletovic, I., Harrison, M. E., Crowell, M. D., Ramirez, F. C., Yows, C. R., Harris, L. A., Pasha, S. F., Gurudu, S. R., Leighton, J. A. & Heigh, R. I., Jun 2013, In : Gastrointestinal Endoscopy. 77, 6, p. 883-887 5 p.

Research output: Contribution to journalArticle

Meperidine
Fentanyl
Endoscopy
Prospective Studies
Intubation
56 Citations (Scopus)

Polyp and adenoma detection rates in the proximal and distal colon

Boroff, E. S., Gurudu, S. R., Hentz, J. G., Leighton, J. A. & Ramirez, F. C., Jun 2013, In : American Journal of Gastroenterology. 108, 6, p. 993-999 7 p.

Research output: Contribution to journalArticle

Polyps
Adenoma
Colon
Transverse Colon
Colonoscopy
56 Citations (Scopus)
Colonoscopy
Ulcerative Colitis
Endoscopy
Light
Polyps

Quality commitment: The newly established american college of gastroenterology quality council to meet the needs of clinical gastroenterology

Kane, S., Leighton, J. A., Kefalas, C., Cohen, L., Katz, P., Rizk, M., Pike, I., Lashner, B., Ho, I., Pochapin, M., Seabrook, M., Greenwald, D., Demarco, D. & Johnson, D., Jan 2013, In : American Journal of Gastroenterology. 108, 1, p. 7-9 3 p.

Research output: Contribution to journalArticle

Quality of Health Care
Medical Societies
Gastroenterology
75 Citations (Scopus)

T Cell-Derived Protein S Engages TAM Receptor Signaling in Dendritic Cells to Control the Magnitude of the Immune Response

CarreraSilva, E., Chan, P., Joannas, L., Errasti, A., Gagliani, N., Bosurgi, L., Jabbour, M., Perry, A., Smith-Chakmakova, F., Mucida, D., Cheroutre, H., Burstyn-Cohen, T., Leighton, J. A., Lemke, G., Ghosh, S. & Rothlin, C., Jul 25 2013, In : Immunity. 39, 1, p. 160-170 11 p.

Research output: Contribution to journalArticle

Protein S
Dendritic Cells
T-Lymphocytes
Adaptive Immunity
Receptor Protein-Tyrosine Kinases
3 Citations (Scopus)

The Dilemma of Incomplete Colonoscopy: What Is the Next Best Test?

Atia, M. A., Ramirez, F. C. & Leighton, J. A., May 2013, In : Clinical Gastroenterology and Hepatology. 11, 5, p. 541-542 2 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Colonoscopy
Colorectal Neoplasms
Decision Making
2012
18 Citations (Scopus)

Comparison of single- Versus double-balloon assisted-colonoscopy for colon examination after previous incomplete standard colonoscopy

Dzeletovic, I., Harrison, M. E., Pasha, S. F., Crowell, M. D., Decker, G. A., Gurudu, S. R. & Leighton, J. A., Oct 2012, In : Digestive Diseases and Sciences. 57, 10, p. 2680-2686 7 p.

Research output: Contribution to journalArticle

Colonoscopy
Colon
Intubation
Cecum
Polyps
113 Citations (Scopus)

Comparison of the yield and miss rate of narrow band imaging and white light endoscopy in patients undergoing screening or surveillance colonoscopy: A meta-analysis

Pasha, S. F., Leighton, J. A., Das, A., Harrison, M. E., Gurudu, S. R., Ramirez, F. C., Fleischer, D. E. & Sharma, V. K., Mar 2012, In : American Journal of Gastroenterology. 107, 3, p. 363-370 8 p.

Research output: Contribution to journalArticle

Narrow Band Imaging
Colonoscopy
Adenoma
Endoscopy
Meta-Analysis
10 Citations (Scopus)

Correlation of two capsule endoscopy scoring systems with fecal calprotectin: Does it really matter?

Gurudu, S. R. & Leighton, J. A., Apr 2012, In : Digestive Diseases and Sciences. 57, 4, p. 827-829 3 p.

Research output: Contribution to journalArticle

Leukocyte L1 Antigen Complex
Capsule Endoscopy
Feces
Crohn Disease
Small Intestine

Current place of capsule endoscopy in Crohn's disease

Islam, R. S., Patel, N. C. & Leighton, J. A., 2012, In : Inflammatory Bowel Disease Monitor. 12, 4, p. 143-148 6 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Crohn Disease
Ileum
Mucous Membrane
Inflammation
68 Citations (Scopus)

Emergence of Gastrointestinal Basidiobolomycosis in the United States, with a Review of Worldwide Cases

Vikram, H. R., Smilack, J. D., Leighton, J. A., Crowell, M. D. & De Petris, G., Jun 15 2012, In : Clinical Infectious Diseases. 54, 12, p. 1685-1691 7 p.

Research output: Contribution to journalArticle

Entomophthorales
Southwestern United States
Mycoses
Saudi Arabia
Centers for Disease Control and Prevention (U.S.)
84 Citations (Scopus)

Increased adenoma detection rate with system-wide implementation of a split-dose preparation for colonoscopy

Gurudu, S. R., Ramirez, F. C., Harrison, M. E., Leighton, J. A. & Crowell, M. D., Sep 2012, In : Gastrointestinal Endoscopy. 76, 3

Research output: Contribution to journalArticle

Colonoscopy
Adenoma
Polyps
Patient Compliance
Quality Improvement
2011
34 Citations (Scopus)

Adenoma detection rate is not influenced by the timing of colonoscopy when performed in half-day blocks

Gurudu, S. R., Ratuapli, S. K., Leighton, J. A., Heigh, R. I. & Crowell, M. D., 2011, In : American Journal of Gastroenterology. 106, 8, p. 1466-1471 6 p.

Research output: Contribution to journalArticle

Colonoscopy
Adenoma
Physicians
Fatigue
Appointments and Schedules
55 Citations (Scopus)

A grading scale to evaluate colon cleansing for the PillCam COLON capsule: A reliability study

Leighton, J. A. & Rex, D. K., 2011, In : Endoscopy. 43, 2, p. 123-127 5 p.

Research output: Contribution to journalArticle

Capsules
Colon
Observer Variation
Israel
Calibration
60 Citations (Scopus)

Performance of the patency capsule compared with nonenteroclysis radiologic examinations in patients with known or suspected intestinal strictures

Yadav, A., Heigh, R. I., Hara, A. K., Decker, G. A., Crowell, M. D., Gurudu, S. R., Pasha, S. F., Fleischer, D. E., Harris, L. A., Post, J. & Leighton, J. A., Oct 2011, In : Gastrointestinal Endoscopy. 74, 4, p. 834-839 6 p.

Research output: Contribution to journalArticle

Capsules
Pathologic Constriction
Capsule Endoscopy
Sensitivity and Specificity
ROC Curve
54 Citations (Scopus)

The role of endoscopic imaging of the small bowel in clinical practice

Leighton, J. A., Jan 2011, In : American Journal of Gastroenterology. 106, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Endoscopes
Celiac Disease
Inflammatory Bowel Diseases
Hemorrhage
2010
83 Citations (Scopus)

A retrograde-viewing device improves detection of adenomas in the colon: a prospective efficacy evaluation (with videos)

Waye, J. D., Heigh, R. I., Fleischer, D. E., Leighton, J. A., Gurudu, S., Aldrich, L. B., Li, J., Ramrakhiani, S., Edmundowicz, S. A., Early, D. S., Jonnalagadda, S., Bresalier, R. S., Kessler, W. R. & Rex, D. K., Mar 2010, In : Gastrointestinal Endoscopy. 71, 3, p. 551-556 6 p.

Research output: Contribution to journalArticle

Adenoma
Polyps
Colonoscopes
Colon
Equipment and Supplies
236 Citations (Scopus)

Capsule endoscopy has a significantly higher diagnostic yield in patients with suspected and established small-bowel crohn's disease: A meta-analysis

Dionisio, P. M., Gurudu, S. R., Leighton, J. A., Leontiadis, G. I., Fleischer, D. E., Hara, A. K., Heigh, R. I., Shiff, A. D. & Sharma, V. K., Jun 2010, In : American Journal of Gastroenterology. 105, 6, p. 1240-1248 9 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Crohn Disease
Meta-Analysis
Radiography
Tomography
7 Citations (Scopus)

Deep enteroscopy in patients with left ventricular assist devices: Practical and technical considerations

Decker, G. A., Miller, E. D., Pasha, S. F., Harrison, M. E. & Leighton, J. A., 2010, In : Endoscopy. 42, SUPPL. 2

Research output: Contribution to journalArticle

1 Citation (Scopus)
Narrow Band Imaging
Papillomavirus Infections
Colonoscopy
Ulcerative Colitis
Rectum