Jonathan A Leighton

2020

Prospective multicenter study to evaluate capsule endoscopy competency using a validated assessment tool

Rajan, E., Martinez, M., Gorospe, E., Al Bawardy, B., Dobashi, A., Mara, K. C., Hansel, S. L., Bruining, D. H., Murray, J. A., Leggett, C. L., Nehra, V., Iyer, P. G., Pasha, S. F., Leighton, J. A., Shiff, A. D., Gurudu, S. R., Raffals, L. E., Lavey, C., Katzka, D. A. & Chen, C. H. H., May 2020, In : Gastrointestinal endoscopy. 91, 5, p. 1140-1145 6 p.

Research output: Contribution to journal › Article

2 Scopus citations

Unique Phenotypic Characteristics and Clinical Course in Patients with Ulcerative Colitis and Primary Sclerosing Cholangitis: A Multicenter US Experience

Wang, M. H., Mousa, O. Y., Friton, J. J., Raffals, L. E., Leighton, J. A., Pasha, S. F., Picco, M. F., Cushing, K. C., Monroe, K., Nix, B. D., Newberry, R. D. & Faubion, W. A., Apr 11 2020, In : Inflammatory bowel diseases. 26, 5, p. 774-779 6 p.

Research output: Contribution to journal › Article

2019

Family History Associates With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases

Samadder, N. J., Valentine, J. F., Guthery, S., Singh, H., Bernstein, C. N., Leighton, J. A., Wan, Y., Wong, J., Boucher, K., Pappas, L., Rowe, K., Burt, R. W., Curtin, K. & Smith, K. R., Aug 2019, In : Clinical Gastroenterology and Hepatology. 17, 9, p. 1807-1813.e1

Research output: Contribution to journal › Article

9 Scopus citations

Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients with Inflammatory Bowel Disease

Wang, M. H., Friton, J. J., Raffals, L. E., Leighton, J. A., Pasha, S. F., Picco, M. F., Cushing, K. C., Monroe, K., Nix, B. D., Newberry, R. D. & Faubion, W. A., Aug 14 2019, In : Journal of Crohn's and Colitis. 13, 8, p. 1036-1043 8 p., jjz017.

Research output: Contribution to journal › Article

1 Scopus citations

The Clinician's Guide to Suspected Small Bowel Bleeding

Kuo, J. R., Pasha, S. F. & Leighton, J. A., Apr 1 2019, In : The American Journal of Gastroenterology. 114, 4, p. 591-598 8 p.

Research output: Contribution to journal › Article

3 Scopus citations

2018

Impact of feedback on adenoma detection rates: Outcomes of quality improvement program

Gurudu, S. R., Boroff, E. S., Crowell, M. D., Atia, M., Umar, S. B., Leighton, J. A., Faigel, D. O. & Ramirez, F. C., Mar 1 2018, In : Journal of Gastroenterology and Hepatology (Australia). 33, 3, p. 645-649 5 p.

Research output: Contribution to journal › Article

5 Scopus citations

Is the level of cleanliness using segmental boston bowel preparation scale associated with a higher adenoma detection rate?

Adike, A., Buras, M. R., Gurudu, S. R., Leighton, J. A., Faigel, D. O., Ruff, K. C., Umar, S. B. & Ramirez, F. C., Mar 5 2018, In : Annals of Gastroenterology. 31, 2, p. 217-223 7 p.

Research output: Contribution to journal › Article

7 Scopus citations

Utility of video capsule endoscopy for longitudinal monitoring of Crohn's disease activity in the small bowel: a prospective study

Melmed, G. Y., Dubinsky, M. C., Rubin, D. T., Fleisher, M., Pasha, S. F., Sakuraba, A., Tiongco, F., Shafran, I., Fernandez-Urien, I., Rosa, B., Papageorgiou, N. P. & Leighton, J. A., Jan 1 2018, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journal › Article

8 Scopus citations

2017

Comparing diagnostic yield of a novel pan-enteric video capsule endoscope with ileocolonoscopy in patients with active Crohn's disease: a feasibility study

Leighton, J. A., Helper, D. J., Gralnek, I. M., Dotan, I., Fernandez-Urien, I., Lahat, A., Malik, P., Mullin, G. E. & Rosa, B., Jan 1 2017, In : Gastrointestinal Endoscopy. 85, 1, p. 196-205.e1

Research output: Contribution to journal › Article

23 Scopus citations

Duodenal gangliocytic paraganglioma: Endoscopy, sonography and F-18 FDG PET/CT imaging

Yang, M., Leighton, J. A., Faigel, D. O. & Katariya, N. N., 2017, (Accepted/In press) In : Digestive and Liver Disease.

Research output: Contribution to journal › Article

1 Scopus citations

Evidence-based guide on capsule endoscopy for small bowel bleeding

Pasha, S. F. & Leighton, J. A., Feb 1 2017, In : Gastroenterology and Hepatology. 13, 2, p. 88-93 6 p.

Research output: Contribution to journal › Article

2 Scopus citations

Identification of antibody against SNRPB, small nuclear ribonucleoprotein-associated proteins B and B', as an autoantibody marker in Crohn's disease using an immunoproteomics approach

Wang, H., Demirkan, G., Bian, X., Wallstrom, G., Barker, K., Karthikeyan, K., Tang, Y., Pasha, S. F., Leighton, J. A., Qiu, J. & LaBaer, J., 2017, In : Journal of Crohn's and Colitis. 11, 7, p. 848-856 9 p.

Research output: Contribution to journal › Article

5 Scopus citations

Optimizing the quality of endoscopy in inflammatory bowel disease: focus on surveillance and management of colorectal dysplasia using interactive image- and video-based teaching

Optimizing Quality of Endoscopy in IBD Group & Optimizing Quality of Endoscopy in IBD Group, Dec 2017, In : Gastrointestinal endoscopy. 86, 6, p. 1107-1117.e1

Research output: Contribution to journal › Article

5 Scopus citations

The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer

Uribe, D. J., Mandell, E. K., Watson, A., Martinez, J. D., Leighton, J. A., Ghosh, S. & Rothlin, C. V., Jul 2017, In : PloS one. 12, 7, e0179979.

Research output: Contribution to journal › Article

11 Scopus citations

2016

Response to Perez-Cuadrado Robles

Gerson, L. B., Fidler, J. L., Cave, D. R. & Leighton, J. A., Feb 1 2016, In : American Journal of Gastroenterology. 111, 2, p. 294-295 2 p.

Research output: Contribution to journal › Article

The Elusive Bleeder: Tips for Avoiding a Wild Goose Chase

Pasha, S. F. & Leighton, J. A., Feb 9 2016, (Accepted/In press) In : American Journal of Gastroenterology.

Research output: Contribution to journal › Article

2015

ACG Clinical Guideline: Diagnosis and Management of Small Bowel Bleeding

Gerson, L. B., Fidler, J. L., Cave, D. R. & Leighton, J. A., Sep 10 2015, In : American Journal of Gastroenterology. 110, 9, p. 1265-1287 23 p.

Research output: Contribution to journal › Article

213 Scopus citations

Double-balloon enteroscopy in Crohn's disease: Findings and impact on management in a multicenter retrospective study

Rahman, A., Ross, A., Leighton, J. A., Schembre, D., Gerson, L., Lo, S. K., Waxman, I., Dye, C. & Semrad, C., Jul 1 2015, In : Gastrointestinal Endoscopy. 82, 1, p. 102-107 6 p.

Research output: Contribution to journal › Article

15 Scopus citations

Nonneoplastic polypectomy during screening colonoscopy: The impact on polyp detection rate, adenoma detection rate, and overall cost

Atia, M. A., Patel, N. C., Ratuapli, S. K., Boroff, E. S., Crowell, M. D., Gurudu, S. R., Faigel, D. O., Leighton, J. A. & Ramirez, F. C., Aug 1 2015, In : Gastrointestinal Endoscopy. 82, 2, p. 370-375.e1

Research output: Contribution to journal › Article

14 Scopus citations

Preface

Kozarek, R. & Leighton, J. A., Jan 1 2015, In : Unknown Journal. p. v-vi

Research output: Contribution to journal › Article

The role of capsule endoscopy in evaluating both suspected and known Crohn's disease

Boroff, E. S. & Leighton, J. A., Jan 1 2015, In : Techniques in Gastrointestinal Endoscopy. 17, 1, p. 5-11 7 p.

Research output: Contribution to journal › Article

2 Scopus citations

Using hybrid change strategies to improve the patient experience in outpatient specialty care

Miranda, R., Glenn, S. W., Leighton, J. A., Pasha, S. F., Gurudu, S. R., Teaford, H. G., Mertz, L. E., Lee, H. R., Mamby, S. A., Johnson, M. F. & Raghu, T. S., 2015, In : Journal of Healthcare Management. 60, 5, p. 363-376 14 p.

Research output: Contribution to journal › Article

1 Scopus citations

2014

Advances in capsule endoscopy in the diagnosis of Crohn's disease

Leighton, J. A., May 2014, In : Gastroenterology and Hepatology. 10, 5, p. 319-321 3 p.

Research output: Contribution to journal › Article

Capsule Endoscopy Is Superior to Small-bowel Follow-through and Equivalent to Ileocolonoscopy in Suspected Crohn's Disease

Leighton, J. A., Gralnek, I. M., Cohen, S. A., Toth, E., Cave, D. R., Wolf, D. C., Mullin, G. E., Ketover, S. R., Legnani, P. E., Seidman, E. G., Crowell, M. D., Bergwerk, A. J., Peled, R. & Eliakim, R., Apr 2014, In : Clinical Gastroenterology and Hepatology. 12, 4, p. 609-615 7 p.

Research output: Contribution to journal › Article

39 Scopus citations

Postcolonoscopy followup recommendations: Comparison with and without use of polyp pathology

Ratuapli, S. K., Gurudu, S. R., Atia, M. A., Crowell, M. D., Umar, S. B., Harrison, M. E., Leighton, J. A. & Ramirez, F. C., 2014, In : Diagnostic and Therapeutic Endoscopy. 2014, 683491.

Research output: Contribution to journal › Article

3 Scopus citations

2013

A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope

Choi, E. H., Mergener, K., Semrad, C., Fisher, L., Cave, D. R., Dodig, M., Burke, C., Leighton, J. A., Kastenberg, D., Simpson, P., Sul, J., Bhattacharya, K., Charles, R., Gerson, L., Weber, L., Eisen, G., Reidel, W., Vargo, J. J., Wakim-Fleming, J. & Lo, S. K., Aug 2013, In : Gastrointestinal endoscopy. 78, 2, p. 325-332 8 p.

Research output: Contribution to journal › Article

17 Scopus citations

Capsule endoscopy in patients with implantable electromedical devices is safe

Harris, L. A., Hansel, S. L., Rajan, E., Srivathsan, K., Rea, R., Crowell, M. D., Fleischer, D. E., Pasha, S. F., Gurudu, S. R., Heigh, R. I., Shiff, A. D., Post, J. K. & Leighton, J. A., 2013, In : Gastroenterology Research and Practice. 2013, 959234.

Research output: Contribution to journal › Article

25 Scopus citations

Downregulation of hematopoietic MUC1 during Experimental colitis increases tumor-promoting myeloid-derived suppressor cells

Poh, T. W., Madsen, C. S., Gorman, J. E., Marler, R. J., Leighton, J. A., Cohen, P. A. & Gendler, S. J., Sep 15 2013, In : Clinical Cancer Research. 19, 18, p. 5039-5052 14 p.

Research output: Contribution to journal › Article

9 Scopus citations

Impact of fentanyl in lieu of meperidine on endoscopy unit efficiency: A prospective comparative study in patients undergoing EGD

Dzeletovic, I., Harrison, M. E., Crowell, M. D., Ramirez, F. C., Yows, C. R., Harris, L. A., Pasha, S. F., Gurudu, S. R., Leighton, J. A. & Heigh, R. I., Jun 2013, In : Gastrointestinal endoscopy. 77, 6, p. 883-887 5 p.

Research output: Contribution to journal › Article

6 Scopus citations

Polyp and adenoma detection rates in the proximal and distal colon

Boroff, E. S., Gurudu, S. R., Hentz, J. G., Leighton, J. A. & Ramirez, F. C., Jun 1 2013, In : American Journal of Gastroenterology. 108, 6, p. 993-999 7 p.

Research output: Contribution to journal › Article

67 Scopus citations

Procedure time and the determination of polypoid abnormalities with experience: Implementation of a chromoendoscopy program for surveillance colonoscopy for ulcerative colitis

Picco, M. F., Pasha, S., Leighton, J. A., Bruining, D., Loftus, E. V., Thomas, C. S., Crook, J. E., Krishna, M. & Wallace, M., Aug 1 2013, In : Inflammatory bowel diseases. 19, 9, p. 1913-1920 8 p.

Research output: Contribution to journal › Article

58 Scopus citations

T Cell-Derived Protein S Engages TAM Receptor Signaling in Dendritic Cells to Control the Magnitude of the Immune Response

CarreraSilva, E. A., Chan, P. Y., Joannas, L., Errasti, A. E., Gagliani, N., Bosurgi, L., Jabbour, M., Perry, A., Smith-Chakmakova, F., Mucida, D., Cheroutre, H., Burstyn-Cohen, T., Leighton, J. A., Lemke, G., Ghosh, S. & Rothlin, C. V., Jul 25 2013, In : Immunity. 39, 1, p. 160-170 11 p.

Research output: Contribution to journal › Article

83 Scopus citations

2012

Comparison of single- Versus double-balloon assisted-colonoscopy for colon examination after previous incomplete standard colonoscopy

Dzeletovic, I., Harrison, M. E., Pasha, S. F., Crowell, M. D., Decker, G. A., Gurudu, S. R. & Leighton, J. A., Oct 1 2012, In : Digestive diseases and sciences. 57, 10, p. 2680-2686 7 p.

Research output: Contribution to journal › Article

19 Scopus citations

Increased adenoma detection rate with system-wide implementation of a split-dose preparation for colonoscopy

Gurudu, S. R., Ramirez, F. C., Harrison, M. E., Leighton, J. A. & Crowell, M. D., Sep 1 2012, In : Gastrointestinal endoscopy. 76, 3, p. 603-608e1

Research output: Contribution to journal › Article

85 Scopus citations

2011

Adenoma detection rate is not influenced by the timing of colonoscopy when performed in half-day blocks

Gurudu, S. R., Ratuapli, S. K., Leighton, J. A., Heigh, R. I. & Crowell, M. D., 2011, In : American Journal of Gastroenterology. 106, 8, p. 1466-1471 6 p.

Research output: Contribution to journal › Article

35 Scopus citations

A grading scale to evaluate colon cleansing for the PillCam COLON capsule: A reliability study

Leighton, J. A. & Rex, D. K., Jan 1 2011, In : Endoscopy. 43, 2, p. 123-127 5 p.

Research output: Contribution to journal › Article

59 Scopus citations

Performance of the patency capsule compared with nonenteroclysis radiologic examinations in patients with known or suspected intestinal strictures

Yadav, A., Heigh, R. I., Hara, A. K., Decker, G. A., Crowell, M. D., Gurudu, S. R., Pasha, S. F., Fleischer, D. E., Harris, L. A., Post, J. & Leighton, J. A., Oct 1 2011, In : Gastrointestinal endoscopy. 74, 4, p. 834-839 6 p.

Research output: Contribution to journal › Article

63 Scopus citations

2010

A retrograde-viewing device improves detection of adenomas in the colon: a prospective efficacy evaluation (with videos)

Waye, J. D., Heigh, R. I., Fleischer, D. E., Leighton, J. A., Gurudu, S., Aldrich, L. B., Li, J., Ramrakhiani, S., Edmundowicz, S. A., Early, D. S., Jonnalagadda, S., Bresalier, R. S., Kessler, W. R. & Rex, D. K., Mar 1 2010, In : Gastrointestinal endoscopy. 71, 3, p. 551-556 6 p.

Research output: Contribution to journal › Article

83 Scopus citations

Deep enteroscopy in patients with left ventricular assist devices: Practical and technical considerations

Decker, G. A., Miller, E. D., Pasha, S. F., Harrison, M. E. & Leighton, J. A., Sep 24 2010, In : Endoscopy. 42, SUPPL. 2, p. E194

Research output: Contribution to journal › Article

7 Scopus citations

Human Papillomavirus-Related Rectal Squamous Cell Carcinoma in a Patient With Ulcerative Colitis Diagnosed on Narrow-Band Imaging

Dzeletovic, I., Pasha, S. & Leighton, J. A., May 1 2010, In : Clinical Gastroenterology and Hepatology. 8, 5, p. e47-e48

Research output: Contribution to journal › Article

1 Scopus citations

Once-Daily Dosing of Delayed-Release Oral Mesalamine (400-mg Tablet) Is as Effective as Twice-Daily Dosing for Maintenance of Remission of Ulcerative Colitis

Sandborn, W. J., Korzenik, J., Lashner, B., Leighton, J. A., Mahadevan, U., Marion, J. F., Safdi, M., Sninsky, C. A., Patel, R. M., Friedenberg, K. A., Dunnmon, P., Ramsey, D. & Kane, S., Apr 2010, In : Gastroenterology. 138, 4, p. 1286-1296.e3

Research output: Contribution to journal › Article

72 Scopus citations

Quality of bowel cleansing for afternoon colonoscopy is influenced by time of administration

Gurudu, S. R., Ratuapli, S., Heigh, R., Dibaise, J., Leighton, J. & Crowell, M., Nov 1 2010, In : American Journal of Gastroenterology. 105, 11, p. 2318-2322 5 p.

Research output: Contribution to journal › Article

44 Scopus citations

The association of ménétrier disease with ulcerative colitis: A case report with implications on the pathogenesis of ménétrier disease

Nguyen, V. X., Nguyen, C. C., Leighton, J. A., Pasha, S. F., Silva, A. C., Heppell, J. P. & De Petris, G., Nov 1 2010, In : Case Reports in Gastroenterology. 4, 1, p. 66-70 5 p.

Research output: Contribution to journal › Article

9 Scopus citations

The face of tropical sprue in 2010

Batheja, M. J., Leighton, J., Azueta, A. & Heigh, R., Nov 29 2010, In : Case Reports in Gastroenterology. 4, 2, p. 168-172 5 p.

Research output: Contribution to journal › Article

18 Scopus citations

2009

Capsule endoscopy in suspected small bowel Crohn's disease: Economic impact of disease diagnosis and treatment

Leighton, J. A., Gralnek, I. M., Richner, R. E., Lacey, M. J. & Papatheofanis, F. J., Dec 7 2009, In : World journal of gastroenterology. 15, 45, p. 5685-5692 8 p.

Research output: Contribution to journal › Article

16 Scopus citations

Complications Associated With Double Balloon Enteroscopy at Nine US Centers

Gerson, L. B., Tokar, J., Chiorean, M., Lo, S., Decker, G. A., Cave, D., BouHaidar, D., Mishkin, D., Dye, C., Haluszka, O., Leighton, J. A., Zfass, A. & Semrad, C., Nov 2009, In : Clinical Gastroenterology and Hepatology. 7, 11, p. 1177-1182.e3

Research output: Contribution to journal › Article

105 Scopus citations

Die rolle der dünndarmendoskopie beim management von patienten mit chronisch-entzündlichen darmerkrankungen: Ein internationaler OMED-ECCO-konsensus

Translated title of the contribution: Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: An international OMED-ECCO consensusBourreille, A., Ignjatovic, A., Aabakken, L., Loftus, E. V., Eliakim, R., Pennazio, M., Bouhnik, Y., Seidman, E., Keuchel, M., Albert, J. G., Ardizzone, S., Bar-Meir, S., Bisschops, R., Despott, E. J., Fortun, P. F., Heuschkel, R., Kammermeier, J., Leighton, J. A., Mantzaris, G. J., Moussata, D. & 13 others, Lo, S., Paulsen, V., Panés, J., Radford-Smith, G., Reinisch, W., Rondonotti, E., Sanders, D. S., Swoger, J. M., Yamamoto, H., Travis, S., Colombel, J. F., Van Gossum, A. & Schulz, H. J., 2009, In : Endoskopie Heute. 22, 4, p. 201-221 21 p.

Research output: Contribution to journal › Article

Double-balloon enteroscopy in the diagnosis and treatment of hemorrhage from small-bowel lymphangioma: a case report

Li, F., Osuoha, C., Leighton, J. A. & Harrison, M. E., Jul 1 2009, In : Gastrointestinal endoscopy. 70, 1, p. 189-190 2 p.

Research output: Contribution to journal › Article

9 Scopus citations

Got Milk? The Endoscopic Diagnosis of an Intraluminal Jejunal Lymphangioma

Han, N. J., Leighton, J. A. & Decker, G. A., Mar 1 2009, In : Clinical Gastroenterology and Hepatology. 7, 3, p. e13

Research output: Contribution to journal › Article

Open-label study of adalimumab in patients with ulcerative colitis including those with prior loss of response or intolerance to infliximab

Afif, W., Leighton, J. A., Hanauer, S. B., Loftus, E. V., Faubion, W. A., Pardi, D. S., Tremaine, W. J., Kane, S. V., Bruining, D. H., Cohen, R. D., Rubin, D. T., Hanson, K. A. & Sandborn, W. J., Nov 26 2009, In : Inflammatory bowel diseases. 15, 9, p. 1302-1307 6 p.

Research output: Contribution to journal › Article

117 Scopus citations

Jonathan A Leighton, MD