John D. Fryer, PhD

Associate Professor

  • 3883 Citations
  • 37 h-Index
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  • 6 Similar Profiles
Apolipoproteins E Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Nicotinic Receptors Medicine & Life Sciences
Cerebral Amyloid Angiopathy Medicine & Life Sciences
Spinocerebellar Ataxias Medicine & Life Sciences
Brain Medicine & Life Sciences
Astrocytes Medicine & Life Sciences

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Projects 2006 2020

Cerebral Amyloid Angiopathy
Alzheimer Disease
Blood Vessels
Alzheimer Disease
Lipoprotein Receptors
Apolipoprotein E4
tau Proteins
Frontotemporal Dementia
Alzheimer Disease
Cerebral Amyloid Angiopathy
Apolipoproteins E
tau Proteins
Frontotemporal Dementia
Bacterial Artificial Chromosomes
Amyotrophic Lateral Sclerosis
Spinocerebellar Ataxias
Purkinje Cells
Microarray Analysis
Neurodegenerative Diseases

Research Output 1999 2019

  • 3883 Citations
  • 37 h-Index
  • 75 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Review article

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Chew, J., Cook, C., Gendron, T. D., Jansen-West, K., Del Rosso, G., Daughrity, L. M., Castanedes-Casey, M., Kurti, A., Stankowski, J. N., Disney, M. D., Rothstein, J. D., Dickson, D. W., Fryer, J. D., Zhang, Y. J. & Petrucelli, L., Feb 15 2019, In : Molecular neurodegeneration. 14, 1, 1 p.

Research output: Contribution to journalArticle

TDP-43 Proteinopathies
Antisense RNA

Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant

Carlomagno, Y., Chung, D. E. C., Yue, M., Kurti, A., Avendano, N. M., Castanedes-Casey, M., Hinkle, K. M., Jansen-West, K., Daughrity, L. M., Tong, J., Phillips, V., Rademakers, R. V., Deture, M., Fryer, J. D., Dickson, D. W., Petrucelli, L. & Cook, C., Jan 23 2019, In : Acta neuropathologica communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy

A matter of balance

Gitler, A. D. & Fryer, J. D., Aug 21 2018, In : eLife. 7

Research output: Contribution to journalComment/debate

RNA-Binding Proteins
Frontotemporal Dementia With Motor Neuron Disease
3 Citations (Scopus)

APOE ε2 is associated with increased tau pathology in primary tauopathy

Zhao, N., Liu, C-C., Van Ingelgom, A. J., Linares, C., Kurti, A., Knight, J. A., Heckman, M. G., Diehl, N. N., Shinohara, M., Martens, Y. A., Attrebi, O. N., Petrucelli, L., Fryer, J. D., Wszolek, Z. K., Graff Radford, N. R., Caselli, R. J., Sanchez-Contreras, M. Y., Rademakers, R. V., Murray, M. E., Koga, S. & 3 othersDickson, D. W., Ross, O. A. & Bu, G. D., Dec 1 2018, In : Nature Communications. 9, 1, 4388.

Research output: Contribution to journalArticle

Apolipoprotein E2
8 Citations (Scopus)

Behavioral and transcriptomic analysis of Trem2-null mice: Not all knockout mice are created equal

Kang, S., Kurti, A., Baker, K. E., Liu, C-C., Colonna, M., Ulrich, J. D., Holtzman, D. M., Bu, G. D. & Fryer, J. D., Jan 15 2018, In : Human Molecular Genetics. 27, 2, p. 211-223 13 p.

Research output: Contribution to journalArticle

Knockout Mice
Myeloid Cells
Neurodegenerative Diseases