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  • 9 Similar Profiles
Apolipoproteins E Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Brain Medicine & Life Sciences
Nicotinic Receptors Medicine & Life Sciences
Pathology Medicine & Life Sciences
Astrocytes Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Projects 2006 2020

Functions of human and mouse Trem2 in vivo

Fryer, J. D.

National Institutes of Health

4/1/163/31/18

Project: Research projectExploratory/Developmental Grants

Alzheimer Disease
Lipoprotein Receptors
Apolipoprotein E4
tau Proteins
Frontotemporal Dementia

The role of Clusterin in cerebral amyloid angiopathy

Fryer, J. D.

National Institutes of Health

9/30/158/31/20

Project: Research projectResearch Project

Cerebral Amyloid Angiopathy
Clusterin
Alzheimer Disease
Brain
Blood Vessels
Clusterin
Alzheimer Disease
Cerebral Amyloid Angiopathy
Apolipoproteins E
Amyloid

Understanding the Mechanisms of TDP-43 Function

Zhang, Y. & Fryer, J. D.

National Institutes of Health

2/15/131/31/16

Project: Research projectExploratory/Developmental Grants

Tyrosine
Phosphorylation
Frontotemporal Dementia
Bacterial Artificial Chromosomes
Amyotrophic Lateral Sclerosis

The role of capicua in spinocerebellar ataxia type 1

Fryer, J. D.

National Institutes of Health

6/1/065/31/09

Project: Research projectPostdoctoral Individual National Research Service Award

Spinocerebellar Ataxias
Ataxin-1
Purkinje Cells
Microarray Analysis
Neurodegenerative Diseases

Research Output 1999 2018

  • 3056 Citations
  • 31 h-Index
  • 65 Article
  • 1 Review article

Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness: A Systematic Review

Sakusic, A., O'Horo, J. C., Dziadzko, M., Volha, D., Ali, R., Singh, T. D., Kashyap, R., Farrell, A. M., Fryer, J. D., Petersen, R., Gajic, O. & Rabinstein, A. A. Jan 1 2018 In : Mayo Clinic Proceedings. 93, 1, p. 68-82 15 p.

Research output: Research - peer-reviewReview article

Critical Illness
Cognitive Dysfunction
Intensive Care Units
Delirium
Critical Care
1 Citations

Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5

Park, S., Lee, S., Lee, C. G., Park, G. Y., Hong, H., Lee, J. S., Kim, Y. M., Lee, S. B., Hwang, D., Choi, Y. S., Fryer, J. D., Im, S. H., Lee, S. W. & Lee, Y. Jul 12 2017 In : Nature Communications. 8, 16037

Research output: Research - peer-reviewArticle

Helper-Inducer T-Lymphocytes
Autoimmunity
Cell Differentiation
cells
T-cells

Derivation and validation of the automated search algorithms to identify cognitive impairment and dementia in electronic health records

Amra, S., O'Horo, J. C., Singh, T. D., Wilson, G. A., Kashyap, R., Petersen, R., Roberts, R. O., Fryer, J. D., Rabinstein, A. A. & Gajic, O. Feb 1 2017 In : Journal of Critical Care. 37, p. 202-205 4 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Dementia
Cognitive Dysfunction
Intensive Care Units
International Classification of Diseases
3 Citations

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

Lu, H. C. , Tan, Q. , Rousseaux, M. W. C. , Wang, W. , Kim, J. Y. , Richman, R. , Wan, Y. W. , Yeh, S. Y. , Patel, J. M. , Liu, X. , Lin, T. , Lee, Y. , Fryer, J. D. , Han, J. , Chahrour, M. , Finnell, R. H. , Lei, Y. , Zurita-Jimenez, M. E. , Ahimaz, P. , Anyane-Yeboa, K. & 17 others Van Maldergem, L., Lehalle, D., Jean-Marcais, N., Mosca-Boidron, A. L., Thevenon, J., Cousin, M. A., Bro, D. E., Lanpher, B. C., Klee, E. W., Alexander, N., Bainbridge, M. N., Orr, H. T., Sillitoe, R. V., Ljungberg, M. C., Liu, Z., Schaaf, C. P. & Zoghbi, H. Y. Mar 30 2017 In : Nature Genetics. 49, 4, p. 527-536 10 p.

Research output: Research - peer-reviewArticle

Phenotype
Ataxin-1
Mutation
Genes
Middle Hypothalamus
1 Citations

Exercise training-induced modification of the gut microbiota persists after microbiota colonization and attenuates the response to chemically-induced colitis in gnotobiotic mice

Allen, J. M., Mailing, L. J., Cohrs, J., Salmonson, C., Fryer, J. D., Nehra, V., Hale, V. L., Kashyap, P., White, B. A. & Woods, J. A. Sep 19 2017 (Accepted/In press) In : Gut Microbes. p. 1-16 16 p.

Research output: Research - peer-reviewArticle

Germ-Free Life
Microbiota
Colitis
Exercise
Gastrointestinal Microbiome