• 2947 Citations
  • 28 Scopus h-Index
20012020
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Research Output 2001 2020

  • 2947 Citations
  • 28 Scopus h-Index
  • 132 Article
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Article
2016
3 Citations (Scopus)

Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities

Prieto, M. L., Ryu, E., Jenkins, G. D., Batzler, A., Nassan, M. M., Cuellar-Barboza, A. B., Pathak, J., McElroy, S. L., Frye, M. A. & Biernacka, J. M., 2016, In : Translational Psychiatry. 6, 8, e870.

Research output: Contribution to journalArticle

Electronic Health Records
Bipolar Disorder
Comorbidity
Single Nucleotide Polymorphism
Odds Ratio
19 Citations (Scopus)

Lipid peroxidation biomarkers in adolescents with or at high-risk for bipolar disorder

Scola, G., McNamara, R. K., Croarkin, P. E., Leffler, J. M., Cullen, K. R., Geske, J. R., Biernacka, J. M., Frye, M. A., Delbello, M. P. & Andreazza, A. C., Mar 1 2016, In : Journal of Affective Disorders. 192, p. 176-183 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Lipid Peroxidation
Biomarkers
Inflammation
Proteins
3 Citations (Scopus)

Modeling X Chromosome Data Using Random Forests: Conquering Sex Bias

Winham, S. J., Jenkins, G. D. & Biernacka, J. M., Feb 1 2016, In : Genetic Epidemiology. 40, 2, p. 123-132 10 p.

Research output: Contribution to journalArticle

Sexism
X Chromosome
Single Nucleotide Polymorphism
Alcoholism
X Chromosome Inactivation
13 Citations (Scopus)

Pharmacogenomics of estrogens on changes in carotid artery intima-medial thickness and coronary arterial calcification: Kronos Early Estrogen Prevention Study

Miller, V. M., Jenkins, G. D., Biernacka, J. M., Heit, J. A., Huggins, G. S., Hodis, H. N., Budoff, M. J., Lobo, R. A., Taylor, H. S., Manson, J. E., Black, D. M., Naftolin, F., Mitchell Harman, S. & De Andrade, M., Jan 1 2016, In : Physiological Genomics. 48, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Carotid Arteries
Estrogens
Innate Immunity
Hormones
29 Citations (Scopus)

Prevalence and correlates of DSM-5 eating disorders in patients with bipolar disorder

McElroy, S. L., Crow, S., Blom, T. J., Biernacka, J. M., Winham, S. J., Geske, J., Cuellar-Barboza, A. B., Bobo, W. V., Prieto, M. L., Veldic, M. D., Mori, N., Seymour, L. R., Bond, D. J. & Frye, M. A., Feb 1 2016, In : Journal of Affective Disorders. 191, p. 216-221 6 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Binge-Eating Disorder
Bulimia Nervosa
Cost of Illness
Diagnostic and Statistical Manual of Mental Disorders
33 Citations (Scopus)

TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics

Gupta, M., Neavin, D., Liu, D., Biernacka, J. M., Hall-Flavin, D., Bobo, W. V., Frye, M. A., Skime, M., Jenkins, G. D., Batzler, A., Kalari, K. R., Matson, W., Bhasin, S. S., Zhu, H., Mushiroda, T., Nakamura, Y., Kubo, M., Wang, L. M., Kaddurah-Daouk, R. & Weinshilboum, R. M., Feb 23 2016, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Pharmacogenetics
Major Depressive Disorder
Serotonin Uptake Inhibitors
Citalopram
Metabolomics
2015
2 Citations (Scopus)

Assessing the effects of multiple markers in genetic association studies

Wang, X. & Biernacka, J. M., 2015, In : Frontiers in Genetics. 5, FEB, 00066.

Research output: Contribution to journalArticle

Genetic Association Studies
8 Citations (Scopus)

Association between history of psychosis and cardiovascular disease in bipolar disorder

Prieto, M. L., Mcelroy, S. L., Hayes, S. N., Sutor, B., Kung, S., Bobo, W. V., Fuentes, M. E., Cuellar-Barboza, A. B., Crow, S., Ösby, U., Chauhan, M., Westman, J., Geske, J. R., Colby, C. L., Ryu, E., Biernacka, J. M. & Frye, M. A., Aug 1 2015, In : Bipolar Disorders. 17, 5, p. 518-527 10 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Psychotic Disorders
Cardiovascular Diseases
Odds Ratio
Confidence Intervals
8 Citations (Scopus)

Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with early-onset bipolar disorder

Nassan, M., Croarkin, P. E., Luby, J. L., Veldic, M. D., Joshi, P. T., Mcelroy, S. L., Post, R. M., Walkup, J. T., Cercy, K., Geske, J. R., Wagner, K. D., Cuellar-Barboza, A. B., Casuto, L., Lavebratt, C., Schalling, M., Jensen, P. S., Biernacka, J. M. & Frye, M. A., Sep 1 2015, In : Bipolar Disorders. 17, 6, p. 645-652 8 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Bipolar Disorder
Odds Ratio
Alleles
Age of Onset
3 Citations (Scopus)

Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent

Winham, S. J., Preuss, U. W., Geske, J. R., Zill, P., Heit, J. A., Bakalkin, G., Biernacka, J. M. & Karpyak, V. M., Oct 27 2015, In : Scientific Reports. 5, 15670.

Research output: Contribution to journalArticle

Alcoholism
Phenotype
Haplotypes
Recurrence
Substance-Related Disorders
13 Citations (Scopus)

Clinical risk factors and serotonin transporter gene variants associated with antidepressant-induced mania

Frye, M. A., McElroy, S. L., Prieto, M. L., Harper, K. L., Walker, D. L., Kung, S., Chauhan, M., Crow, S., Sutor, B., Galardy, C. W., Veldic, M. D., Palmer, B. A., Geske, J. R., Fuentes, M., Cuellar-Barboza, A. B., Seymour, L. R., Mori, N. & Biernacka, J. M., Feb 1 2015, In : The Journal of clinical psychiatry. 76, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Bipolar Disorder
Antidepressive Agents
Genes
Haplotypes
22 Citations (Scopus)

Development of a bipolar disorder biobank: differential phenotyping for subsequent biomarker analyses

Frye, M. A., McElroy, S. L., Fuentes, M., Sutor, B., Schak, K. M., Galardy, C. W., Palmer, B. A., Prieto, M. L., Kung, S., Sola, C. L., Ryu, E., Veldic, M. D., Geske, J., Cuellar-Barboza, A., Seymour, L. R., Mori, N., Crowe, S., Rummans, T. A. & Biernacka, J. M., Dec 30 2015, In : International Journal of Bipolar Disorders. 3, 1, 14.

Research output: Contribution to journalArticle

Bipolar Disorder
Biomarkers
Demography
Phenotype
Exanthema
15 Citations (Scopus)

Elevated baseline serum glutamate as a pharmacometabolomic biomarker for Acamprosate treatment outcome in alcohol-dependent subjects

Nam, H. W., Karpyak, V. M., Hinton, D. J., Geske, J. R., Ho, A. M. C., Prieto, M. L., Biernacka, J. M., Frye, M. A., Weinshilboum, R. M. & Choi, D. S., 2015, In : Translational Psychiatry. 5, 8, 120.

Research output: Contribution to journalArticle

Glutamic Acid
Biomarkers
Alcohols
Serum
acamprosate
18 Citations (Scopus)

Feasibility of investigating differential proteomic expression in depression: implications for biomarker development in mood disorders

Frye, M. A., Nassan, M., Jenkins, G. D., Kung, S., Veldic, M. D., Palmer, B. A., Feeder, S. E., Tye, S. J., Choi, D. S. & Biernacka, J. M., 2015, In : Translational Psychiatry. 5, p. e689

Research output: Contribution to journalArticle

Growth Differentiation Factor 15
Mood Disorders
Proteomics
Matrix Metalloproteinase 7
Bipolar Disorder
5 Citations (Scopus)

Feasibility of investigating differential proteomic expression in depression: Implications for biomarker development in mood disorders

Frye, M. A., Nassan, M., Jenkins, G. D., Kung, S., Veldic, M. D., Palmer, B. A., Feeder, S. E., Tye, S. J., Choi, D. S. & Biernacka, J. M., Dec 1 2015, In : Translational Psychiatry. 5, e687.

Research output: Contribution to journalArticle

Growth Differentiation Factor 15
Mood Disorders
Proteomics
Matrix Metalloproteinase 7
Bipolar Disorder
50 Citations (Scopus)

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Hou, L., Bergen, S. E., Akula, N., Song, J., Hultman, C. M., Landén, M., Adli, M., Alda, M., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Badner, J. A., Barrett, T. B., Bauer, M., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S., Berrettini, W. H. & 119 others, Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Bloss, C. S., Brichant-Petitjean, C., Bui, E. T., Byerley, W., Cervantes, P., Chillotti, C., Cichon, S., Colom, F., Coryell, W., Craig, D. W., Cruceanu, C., Czerski, P. M., Davis, T., Dayer, A., Degenhardt, F., Del Zompo, M., DePaulo, J. R., Edenberg, H. J., Étain, B., Falkai, P., Foroud, T., Forstner, A. J., Frisén, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Gershon, E. S., Goes, F. S., Greenwood, T. A., Grigoroiu-Serbanescu, M., Hauser, J., Heilbronner, U., Heilmann-Heimbach, S., Herms, S., Hipolito, M., Hitturlingappa, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., Koller, D. L., König, B., Lackner, N., Laje, G., Lang, M., Lavebratt, C., Lawson, W. B., Leboyer, M., Leckband, S. G., Liu, C., Maaser, A., Mahon, P. B., Maier, W., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McInnis, M. G., McKinney, R., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Mühleisen, T. W., Nievergelt, C. M., Nöthen, M. M., Novák, T., Nurnberger, J. I., Nwulia, E. A., Ösby, U., Pfennig, A., Potash, J. B., Propping, P., Reif, A., Reininghaus, E., Rice, J., Rietschel, M., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scheftner, W. A., Schofield, P. R., Schork, N. J., Schulze, T. G., Schumacher, J., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Smith, E. N., Squassina, A., Stamm, T., Stopkova, P., Streit, F., Strohmaier, J., Szelinger, S., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Volkert, J., Witt, S. H., Wright, A., Zandi, P. P., Zhang, P., Zollner, S. & McMahon, F. J., 2015, In : Human Molecular Genetics. 25, 15, p. 3383-3394 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
X Chromosome
Lithium
Odds Ratio
6 Citations (Scopus)

National Survey and Community Advisory Board Development for a Bipolar Disorder Biobank

Frye, M. A., Doederlein, A., Koenig, B., Mcelroy, S. L., Nassan, M., Seymour, L. R., Biernacka, J. M. & Daniels, A. S., Sep 1 2015, In : Bipolar Disorders. 17, 6, p. 598-605 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Research
DNA
Informed Consent
Medical Records
17 Citations (Scopus)

Sex differences in the risk of rapid cycling and other indicators of adverse illness course in patients with bipolar I and II disorder

Erol, A., Winham, S. J., Mcelroy, S. L., Frye, M. A., Prieto, M. L., Cuellar-Barboza, A. B., Fuentes, M., Geske, J., Mori, N., Biernacka, J. M. & Bobo, W. V., Sep 1 2015, In : Bipolar Disorders. 17, 6, p. 670-676 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Sex Characteristics
Body Mass Index
Precision Medicine
Sample Size
13 Citations (Scopus)

The association between sleep disturbances and alcohol relapse: A 12-month observational cohort study

Kolla, B. P., Schneekloth, T., Mansukhani, M., Biernacka, J. M., Hall-Flavin, D., Karpyak, V. M., Geske, J. & Frye, M. A., Jun 1 2015, In : American Journal on Addictions. 24, 4, p. 362-367 6 p.

Research output: Contribution to journalArticle

compound A 12
Observational Studies
Sleep
Cohort Studies
Alcohols
55 Citations (Scopus)

The International SSRI Pharmacogenomics Consortium (ISPC): A genome-wide association study of antidepressant treatment response

Biernacka, J. M., Sangkuhl, K., Jenkins, G., Whaley, R. M., Barman, P., Batzler, A., Altman, R. B., Arolt, V., Brockmöller, J., Chen, C. H., Domschke, K., Hall-Flavin, D. K., Hong, C. J., Illi, A., Ji, Y., Kampman, O., Kinoshita, T., Leinonen, E., Liou, Y. J., Mushiroda, T. & 12 others, Nonen, S., Skime, M. K., Wang, L. M., Baune, B. T., Kato, M., Liu, Y. L., Praphanphoj, V., Stingl, J. C., Tsai, S. J., Kubo, M., Klein, T. E. & Weinshilboum, R. M., May 26 2015, In : Translational Psychiatry. 5, 4, A047.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pharmacogenetics
Serotonin Uptake Inhibitors
Antidepressive Agents
Depression
2014
9 Citations (Scopus)

Alpha-synuclein repeat variants and survival in parkinson's disease

Chung, S. J., Biernacka, J. M., Armasu, S. M., Anderson, K., Frigerio, R., Aasly, J. O., Annesi, G., Bentivoglio, A. R., Brighina, L., Chartier-Harlin, M. C., Goldwurm, S., Hadjigeorgiou, G., Jasinska-Myga, B., Jeon, B. S., Kim, Y. J., Krüger, R., Lesage, S., Markopoulou, K., Mellick, G., Morrison, K. E. & 16 others, Puschmann, A., Tan, E. K., Crosiers, D., Theuns, J., Van Broeckhoven, C., Wirdefeldt, K., Wszolek, Z. K., Elbaz, A., Maraganore, D. M., Yahalom, G., Orlev, Y., Cohen, O. S., Kozlova, E., Friedman, E., Inzelberg, R. & Hassin-Baer, S., 2014, In : Movement Disorders. 29, 8, p. 1053-1057 5 p.

Research output: Contribution to journalArticle

alpha-Synuclein
Synucleins
Parkinson Disease
Genotype
Dinucleotide Repeats
12 Citations (Scopus)

Association of GATA4 sequence variation with alcohol dependence

Karpyak, V. M., Winham, S. J., Biernacka, J. M., Cunningham, J. M., Lewis, K. A., Geske, J. R., Colby, C. L., Abulseoud, O. A., Hall-Flavin, D. K., Loukianova, L. L., Schneekloth, T. D., Frye, M. A., Heit, J. A. & Mrazek, D. A., Mar 2014, In : Addiction Biology. 19, 2, p. 312-315 4 p.

Research output: Contribution to journalArticle

Alcoholism
Single Nucleotide Polymorphism
Alcohols
Genes
acamprosate
21 Citations (Scopus)

Bipolar disorder with comorbid binge eating history: A genome-wide association study implicates APOB

Winham, S. J., Cuellar-Barboza, A. B., McElroy, S. L., Oliveros, A., Crow, S., Colby, C. L., Choi, D. S., Chauhan, M., Frye, M. A. & Biernacka, J. M., Aug 20 2014, In : Journal of Affective Disorders. 165, p. 151-158 8 p.

Research output: Contribution to journalArticle

Bulimia
Genome-Wide Association Study
Bipolar Disorder
Single Nucleotide Polymorphism
History
23 Citations (Scopus)

Current landscape, unmet needs, and future directions for treatment of bipolar depression

Frye, M. A., Prieto, M. L., Bobo, W. V., Kung, S., Veldic, M. D., Alarcon, R. D., Moore, K. M., Choi, D. S., Biernacka, J. M. & Tye, S. J., Dec 1 2014, In : Journal of Affective Disorders. 169, S1, p. S17-S23

Research output: Contribution to journalArticle

Bipolar Disorder
Precision Medicine
Therapeutics
Antidepressive Agents
Direction compound
18 Citations (Scopus)

Does α-synuclein have a dual and opposing effect in preclinical vs. clinical Parkinson's disease?

Markopoulou, K., Biernacka, J. M., Armasu, S. M., Anderson, K. J., Ahlskog, J. E., Chase, B. A., Chung, S. J., Cunningham, J. M., Farrer, M., Frigerio, R. & Maraganore, D. M., 2014, In : Parkinsonism and Related Disorders. 20, 6, p. 584-589 6 p.

Research output: Contribution to journalArticle

Synucleins
Parkinson Disease
Genotype
Alzheimer Disease
Interviews
Psychopharmacology
Pharmacogenetics
Antidepressive Agents
Depression
Research
32 Citations (Scopus)

Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate

Karpyak, V. M., Biernacka, J. M., Geske, J. R., Jenkins, G. D., Cunningham, J. M., Rüegg, J., Kononenko, O., Leontovich, A. A., Abulseoud, O. A., Hall-Flavin, D. K., Loukianova, L. L., Schneekloth, T. D., Skime, M. K., Frank, J., Nöthen, M. M., Rietschel, M., Kiefer, F., Mann, K. F., Weinshilboum, R. M., Frye, M. A. & 1 others, Choi, D. S., 2014, In : Translational Psychiatry. 4, p. e462

Research output: Contribution to journalArticle

Genetic Markers
Alcohols
Linkage Disequilibrium
Statistical Models
Alcoholics
8 Citations (Scopus)

Integrative gene set analysis: Application to platinum pharmacogenomics

Fridley, B. L., Abo, R., Tan, X. L., Jenkins, G. D., Batzler, A., Moyer, A., Biernacka, J. M. & Wang, L. M., Jan 1 2014, In : OMICS A Journal of Integrative Biology. 18, 1, p. 34-41 8 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Platinum
Genes
DNA Copy Number Variations
Cells
19 Citations (Scopus)

Lack of Replication of the GRIN2A-by-Coffee Interaction in Parkinson Disease

Ahmed, I., Lee, P. C., Lill, C. M., Searles Nielsen, S., Artaud, F., Gallagher, L. G., Loriot, M. A., Mulot, C., Nacfer, M., Liu, T., Biernacka, J. M., Armasu, S., Anderson, K., Farin, F. M., Funch Lassen, C., Hansen, J., Olsen, J. H., Bertram, L., Maraganore, D. M., Checkoway, H. & 2 others, Ritz, B. & Elbaz, A., Nov 1 2014, In : PLoS Genetics. 10, 11

Research output: Contribution to journalArticle

Gene-Environment Interaction
genotype-environment interaction
Parkinson disease
Genome-Wide Association Study
Coffee
11 Citations (Scopus)

The course of sleep disturbances in early alcohol recovery: An observational cohort study

Kolla, B. P., Schneekloth, T., Biernacka, J. M., Mansukhani, M., Geske, J., Karpyak, V. M., Hall-Flavin, D., Louikianova, L. & Frye, M. A., Jan 2014, In : American Journal on Addictions. 23, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

Observational Studies
Sleep
Cohort Studies
Alcohols
Hypnotics and Sedatives
21 Citations (Scopus)

Treatment outcomes of depression: The pharmacogenomic research network antidepressant medication pharmacogenomic study

Mrazek, D. A., Biernacka, J. M., McAlpine, D. E., Benitez, J., Karpyak, V. M., Williams, M. D., Hall-Flavin, D. K., Netzel, P. J., Passov, V., Rohland, B. M., Shinozaki, G., Hoberg, A. A., Snyder, K. A., Drews, M. S., Skime, M. K., Sagen, J. A., Schaid, D. J., Weinshilboum, R. M. & Katzelnick, D. J., 2014, In : Journal of Clinical Psychopharmacology. 34, 3, p. 313-317 5 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Antidepressive Agents
Depression
Major Depressive Disorder
Serotonin Uptake Inhibitors
2013
28 Citations (Scopus)

A retrospective study of gender differences in depressive symptoms and risk of relapse in patients with alcohol dependence

Abulseoud, O. A., Karpyak, V. M., Schneekloth, T., Hall-Flavin, D. K., Loukianova, L. L., Geske, J. R., Biernacka, J. M., Mrazek, D. A. & Frye, M. A., Sep 2013, In : American Journal on Addictions. 22, 5, p. 437-442 6 p.

Research output: Contribution to journalArticle

Alcoholism
Retrospective Studies
Depression
Recurrence
Equipment and Supplies
62 Citations (Scopus)

Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report

Manchia, M., Adli, M., Akula, N., Ardau, R., Aubry, J. M., Backlund, L., Banzato, C. E. M., Baune, B. T., Bellivier, F., Bengesser, S., Biernacka, J. M., Brichant-Petitjean, C., Bui, E., Calkin, C. V., Cheng, A. T. A., Chillotti, C., Cichon, S., Clark, S., Czerski, P. M., Dantas, C. & 80 others, Del Zompo, M., DePaulo, J. R., Detera-Wadleigh, S. D., Etain, B., Falkai, P., Frisén, L., Frye, M. A., Fullerton, J., Gard, S., Garnham, J., Goes, F. S., Grof, P., Gruber, O., Hashimoto, R., Hauser, J., Heilbronner, U., Hoban, R., Hou, L., Jamain, S., Kahn, J. P., Kassem, L., Kato, T., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., Kuo, P. H., Kusumi, I., Laje, G., Lavebratt, C., Leboyer, M., Leckband, S. G., López Jaramillo, C. A., Maj, M., Malafosse, A., Martinsson, L., Masui, T., Mitchell, P. B., Mondimore, F., Monteleone, P., Nallet, A., Neuner, M., Novák, T., O'Donovan, C., Ösby, U., Ozaki, N., Perlis, R. H., Pfennig, A., Potash, J. B., Reich-Erkelenz, D., Reif, A., Reininghaus, E., Richardson, S., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schubert, O. K., Schweizer, B., Seemüller, F., Grigoroiu-Serbanescu, M., Severino, G., Seymour, L. R., Slaney, C., Smoller, J. W., Squassina, A., Stamm, T., Steele, J., Stopkova, P., Tighe, S. K., Tortorella, A., Turecki, G., Wray, N. R., Wright, A., Zandi, P. P., Zilles, D., Bauer, M., Rietschel, M., McMahon, F. J., Schulze, T. G. & Alda, M., Jun 19 2013, In : PLoS One. 8, 6, e65636.

Research output: Contribution to journalArticle

lithium
Bipolar Disorder
Lithium
Therapeutics
pharmacogenomics
18 Citations (Scopus)

Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states

Karpyak, V. M., Winham, S. J., Preuss, U. W., Zill, P., Cunningham, J. M., Walker, D. L., Lewis, K. A., Geske, J. R., Colby, C. L., Abulseoud, O. A., Hall-Flavin, D. K., Loukianova, L. L., Schneekloth, T. D., Frye, M. A., Bazov, I., Heit, J. A., Bakalkin, G., Mrazek, D. A. & Biernacka, J. M., Jun 2013, In : International Journal of Neuropsychopharmacology. 16, 5, p. 975-985 11 p.

Research output: Contribution to journalArticle

Alcoholism
Single Nucleotide Polymorphism
Genes
Depression
Haplotypes
25 Citations (Scopus)
Random Forest
Genes
High-dimensional Data
Gene
Effect Size
34 Citations (Scopus)

Clinical phenotype of bipolar disorder with comorbid binge eating disorder

McElroy, S. L., Crow, S., Biernacka, J. M., Winham, S. J., Geske, J., Barboza, A. B. C., Prieto, M. L., Chauhan, M., Seymour, L. R., Mori, N. & Frye, M. A., Sep 25 2013, In : Journal of Affective Disorders. 150, 3, p. 981-986 6 p.

Research output: Contribution to journalArticle

Binge-Eating Disorder
Bipolar Disorder
Phenotype
Obesity
Cost of Illness
42 Citations (Scopus)

FKBP5 genetic variation: Association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder

Ellsworth, K. A., Moon, I., Eckloff, B. W., Fridley, B. L., Jenkins, G. D., Batzler, A., Biernacka, J. M., Abo, R., Brisbin, A., Ji, Y., Hebbring, S., Wieben, E. D., Mrazek, D. A., Weinshilboum, R. M. & Wang, L. M., Mar 2013, In : Pharmacogenetics and Genomics. 23, 3, p. 156-166 11 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Single Nucleotide Polymorphism
DNA
Odds Ratio
27 Citations (Scopus)
Gene-Environment Interaction
Genome-Wide Association Study
Psychiatry
Genome
Genes
15 Citations (Scopus)

Genetic susceptibility loci, environmental exposures, and Parkinson's disease: A case-control study of gene-environment interactions

Chung, S. J., Armasu, S. M., Anderson, K. J., Biernacka, J. M., Lesnick, T. G., Rider, D. N., Cunningham, J. M., Ahlskog, J. E., Frigerio, R. & Maraganore, D. M., Jun 2013, In : Parkinsonism and Related Disorders. 19, 6, p. 595-599 5 p.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Genetic Loci
Environmental Exposure
Genetic Predisposition to Disease
Parkinson Disease
40 Citations (Scopus)

Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2

Winham, S. J., Cuellar-Barboza, A. B., Oliveros, A., McElroy, S. L., Crow, S., Colby, C., Choi, D. S., Chauhan, M., Frye, M. A. & Biernacka, J. M., Dec 10 2013, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Body Mass Index
Alleles
Single Nucleotide Polymorphism
21 Citations (Scopus)

Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence

Biernacka, J. M., Geske, J., Jenkins, G. D., Colby, C., Rider, D. N., Karpyak, V. M., Choi, D. S. & Fridley, B. L., Mar 2013, In : International Journal of Neuropsychopharmacology. 16, 2, p. 271-278 8 p.

Research output: Contribution to journalArticle

Alcoholism
Genome
Genes
Single Nucleotide Polymorphism
Encyclopedias
6 Citations (Scopus)

PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort

Preuss, U. W., Winham, S. J., Biernacka, J. M., Geske, J. R., Bakalkin, G., Koller, G., Zill, P., Soyka, M. & Karpyak, V. M., Nov 6 2013, In : PLoS One. 8, 11, e78688.

Research output: Contribution to journalArticle

craving
drinking
Drinking
Alcohols
Association reactions
39 Citations (Scopus)

Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: Genome-wide associations and functional genomics

Ji, Y., Biernacka, J. M., Hebbring, S., Chai, Y., Jenkins, G. D., Batzler, A., Snyder, K. A., Drews, M. S., Desta, Z., Flockhart, D., Mushiroda, T., Kubo, M., Nakamura, Y., Kamatani, N., Schaid, D. J., Weinshilboum, R. M. & Mrazek, D. A., Oct 2013, In : Pharmacogenomics Journal. 13, 5, p. 456-463 8 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Major Depressive Disorder
Serotonin Uptake Inhibitors
Genomics
Single Nucleotide Polymorphism
26 Citations (Scopus)

Replication of Genome Wide Association Studies of Alcohol Dependence: Support for Association with Variation in ADH1C

Biernacka, J. M., Geske, J. R., Schneekloth, T. D., Frye, M. A., Cunningham, J. M., Choi, D. S., Tapp, C. L., Lewis, B. R., Drews, M. S., L.Pietrzak, T., Colby, C. L., Hall-Flavin, D. K., Loukianova, L. L., Heit, J. A., Mrazek, D. A. & Karpyak, V. M., Mar 13 2013, In : PLoS One. 8, 3, e58798.

Research output: Contribution to journalArticle

Genome-Wide Association Study
alcohol abuse
single nucleotide polymorphism
Alcoholism
Single Nucleotide Polymorphism
2012
26 Citations (Scopus)

Alcohol craving as a predictor of relapse.

Schneekloth, T. D., Biernacka, J. M., Hall-Flavin, D. K., Karpyak, V. M., Frye, M. A., Loukianova, L. L., Stevens, S. R., Drews, M. S., Geske, J. R. & Mrazek, D. A., Nov 2012, In : The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions. 21 Suppl 1

Research output: Contribution to journalArticle

Alcohols
Recurrence
Residential Treatment
Craving
Alcoholism
21 Citations (Scopus)

Catechol O-methyltransferase pharmacogenomics and selective serotonin reuptake inhibitor response

Ji, Y., Biernacka, J. M., Snyder, K., Drews, M., Pelleymounter, L. L., Colby, C., Wang, L. M., Mrazek, D. A. & Weinshilboum, R. M., 2012, In : Pharmacogenomics Journal. 12, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Pharmacogenetics
Serotonin Uptake Inhibitors
Citalopram
Single Nucleotide Polymorphism
343 Citations (Scopus)

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDgene database

Lill, C. M., Roehr, J. T., McQueen, M. B., Kavvoura, F. K., Bagade, S., Schjeide, B. M. M., Schjeide, L. M., Meissner, E., Zauft, U., Allen, N. C., Liu, T., Schilling, M., Anderson, K. J., Beecham, G., Berg, D., Biernacka, J. M., Brice, A., DeStefano, A. L., Do, C. B., Eriksson, N. & 34 others, Factor, S. A., Farrer, M. J., Foroud, T., Gasser, T., Hamza, T., Hardy, J. A., Heutink, P., Hill-Burns, E. M., Klein, C., Latourelle, J. C., Maraganore, D. M., Martin, E. R., Martinez, M., Myers, R. H., Nalls, M. A., Pankratz, N., Payami, H., Satake, W., Scott, W. K., Sharma, M., Singleton, A. B., Stefansson, K., Toda, T., Tung, J. Y., Vance, J., Wood, N. W., Zabetian, C. P., Young, P., Tanzi, R. E., Khoury, M. J., Zipp, F., Lehrach, H., Ioannidis, J. P. A. & Bertram, L., Mar 2012, In : PLoS Genetics. 8, 3, e1002548.

Research output: Contribution to journalArticle

Parkinson disease
Parkinson Disease
Meta-Analysis
Genome-Wide Association Study
genome
18 Citations (Scopus)

Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence

Karpyak, V. M., Geske, J. R., Colby, C. L., Mrazek, D. A. & Biernacka, J. M., Jul 2012, In : Addiction Biology. 17, 4, p. 798-806 9 p.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
N-Methylaspartate
Alcoholism
Single Nucleotide Polymorphism
Genes
16 Citations (Scopus)

Genomic determinants of motor and cognitive outcomes in Parkinson's disease

Chung, S. J., Armasu, S. M., Biernacka, J. M., Anderson, K. J., Lesnick, T. G., Rider, D. N., Cunningham, J. M., Eric Ahlskog, J., Frigerio, R. & Maraganore, D. M., Aug 2012, In : Parkinsonism and Related Disorders. 18, 7, p. 881-886 6 p.

Research output: Contribution to journalArticle

Parkinson Disease
Single Nucleotide Polymorphism
Genes
Genome-Wide Association Study
Proportional Hazards Models