• 2947 Citations
  • 28 Scopus h-Index
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Research Output 2001 2020

  • 2947 Citations
  • 28 Scopus h-Index
  • 132 Article
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12 Citations (Scopus)

Accumulating evidence for a role of TCF7L2 variants in bipolar disorder with elevated body mass index

Cuellar-Barboza, A. B., Winham, S. J., Mcelroy, S. L., Geske, J. R., Jenkins, G. D., Colby, C. L., Prieto, M. L., Ryu, E., Cunningham, J. M., Frye, M. A. & Biernacka, J. M., Mar 1 2016, In : Bipolar Disorders. 18, 2, p. 124-135 12 p.

Research output: Contribution to journalArticle

T Cell Transcription Factor 1
Bipolar Disorder
Body Mass Index
Single Nucleotide Polymorphism
Wnt Signaling Pathway
3 Citations (Scopus)
Single Nucleotide Polymorphism
5 Citations (Scopus)

A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model

Nassan, M., Li, Q., Croarkin, P. E., Chen, W., Colby, C. L., Veldic, M. D., McElroy, S. L., Jenkins, G. D., Ryu, E., Cunningham, J. M., Leboyer, M., Frye, M. A. & Biernacka, J. M., Jan 15 2017, In : Journal of Affective Disorders. 208, p. 120-129 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Neurogenesis
Bipolar Disorder
Single Nucleotide Polymorphism
GABA-A Receptors
26 Citations (Scopus)

Alcohol craving as a predictor of relapse.

Schneekloth, T. D., Biernacka, J. M., Hall-Flavin, D. K., Karpyak, V. M., Frye, M. A., Loukianova, L. L., Stevens, S. R., Drews, M. S., Geske, J. R. & Mrazek, D. A., Nov 2012, In : The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions. 21 Suppl 1

Research output: Contribution to journalArticle

Alcohols
Recurrence
Residential Treatment
Craving
Alcoholism

Alcohol Craving Predicts Relapse After Residential Addiction Treatment

Stohs, M. E., Schneekloth, T. D., Geske, J. R., Biernacka, J. M. & Karpyak, V. M., Mar 1 2019, In : Alcohol and alcoholism (Oxford, Oxfordshire). 54, 2, p. 167-172 6 p.

Research output: Contribution to journalArticle

Residential Treatment
Alcohols
Recurrence
Therapeutics
Craving
9 Citations (Scopus)

Alpha-synuclein repeat variants and survival in parkinson's disease

Chung, S. J., Biernacka, J. M., Armasu, S. M., Anderson, K., Frigerio, R., Aasly, J. O., Annesi, G., Bentivoglio, A. R., Brighina, L., Chartier-Harlin, M. C., Goldwurm, S., Hadjigeorgiou, G., Jasinska-Myga, B., Jeon, B. S., Kim, Y. J., Krüger, R., Lesage, S., Markopoulou, K., Mellick, G., Morrison, K. E. & 16 others, Puschmann, A., Tan, E. K., Crosiers, D., Theuns, J., Van Broeckhoven, C., Wirdefeldt, K., Wszolek, Z. K., Elbaz, A., Maraganore, D. M., Yahalom, G., Orlev, Y., Cohen, O. S., Kozlova, E., Friedman, E., Inzelberg, R. & Hassin-Baer, S., 2014, In : Movement Disorders. 29, 8, p. 1053-1057 5 p.

Research output: Contribution to journalArticle

alpha-Synuclein
Synucleins
Parkinson Disease
Genotype
Dinucleotide Repeats
2 Citations (Scopus)

Analysis of the influence of microRNAs in lithium response in bipolar disorder

Reinbold, C. S., Forstner, A. J., Hecker, J., Fullerton, J. M., Hoffmann, P., Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N., Ardau, R., Arias, B., Backlund, L., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Marie-Claire, C. & 101 others, Cervantes, P., Chen, G. B., Chen, H. C., Chillotti, C., Clark, S. R., Colom, F., Cousins, D. A., Cruceanu, C., Czerski, P. M., Dayer, A., Étain, B., Falkai, P., Frisén, L., Gard, S., Garnham, J. S., Goes, F. S., Grof, P., Gruber, O., Hashimoto, R., Hauser, J., Herms, S., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Lackner, N., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Jaramillo, C. A. L., MacQueen, G., Manchia, M., Martinsson, L., Mattheisen, M., McCarthy, M. J., McElroy, S. L., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Ösby, U., Ozaki, N., Perlis, R. H., Pfennig, A., Reich-Erkelenz, D., Rouleau, G. A., Schofield, P. R., Schubert, K. O., Schweizer, B. W., Seemüller, F., Severino, G., Shekhtman, T., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Smoller, J. W., Squassina, A., Stamm, T. J., Stopkova, P., Tighe, S. K., Tortorella, A., Turecki, G., Volkert, J., Witt, S. H., Wright, A. J., Trevor Young, L., Zandi, P. P., Potash, J. B., DePaulo, J. R., Bauer, M., Reininghaus, E., Novák, T., Aubry, J. M., Maj, M., Baune, B. T., Mitchell, P. B., Vieta, E., Frye, M. A., Rybakowski, J. K., Kuo, P. H., Kato, T., Grigoroiu-Serbanescu, M., Reif, A., Zompo, M. D., Bellivier, F., Schalling, M., Wray, N. R., Kelsoe, J. R., Alda, M., McMahon, F. J., Schulze, T. G., Rietschel, M., Nöthen, M. M. & Cichon, S., May 31 2018, In : Frontiers in Psychiatry. 9, MAY, 207.

Research output: Contribution to journalArticle

MicroRNAs
Bipolar Disorder
Lithium
Genome-Wide Association Study
Genome
10 Citations (Scopus)

Anterior Cingulate Glutamate Is Reduced by Acamprosate Treatment in Patients with Alcohol Dependence

Frye, M. A., Hinton, D. J., Karpyak, V. M., Biernacka, J. M., Gunderson, L. J., Feeder, S. E., Choi, D. S. & Port, J. D., Dec 1 2016, In : Journal of Clinical Psychopharmacology. 36, 6, p. 669-674 6 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Alcoholism
Glutamic Acid
Therapeutics
Alcohols
1 Citation (Scopus)

Application of the parametric bootstrap for gene-set analysis of gene–environment interactions

Coombes, B. J. & Biernacka, J. M., Jan 1 2018, (Accepted/In press) In : European Journal of Human Genetics.

Research output: Contribution to journalArticle

Genes
Wnt Signaling Pathway
Bipolar Disorder
Single Nucleotide Polymorphism
Obesity
28 Citations (Scopus)

A retrospective study of gender differences in depressive symptoms and risk of relapse in patients with alcohol dependence

Abulseoud, O. A., Karpyak, V. M., Schneekloth, T., Hall-Flavin, D. K., Loukianova, L. L., Geske, J. R., Biernacka, J. M., Mrazek, D. A. & Frye, M. A., Sep 2013, In : American Journal on Addictions. 22, 5, p. 437-442 6 p.

Research output: Contribution to journalArticle

Alcoholism
Retrospective Studies
Depression
Recurrence
Equipment and Supplies
2 Citations (Scopus)

Assessing the effects of multiple markers in genetic association studies

Wang, X. & Biernacka, J. M., 2015, In : Frontiers in Genetics. 5, FEB, 00066.

Research output: Contribution to journalArticle

Genetic Association Studies
62 Citations (Scopus)

Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report

Manchia, M., Adli, M., Akula, N., Ardau, R., Aubry, J. M., Backlund, L., Banzato, C. E. M., Baune, B. T., Bellivier, F., Bengesser, S., Biernacka, J. M., Brichant-Petitjean, C., Bui, E., Calkin, C. V., Cheng, A. T. A., Chillotti, C., Cichon, S., Clark, S., Czerski, P. M., Dantas, C. & 80 others, Del Zompo, M., DePaulo, J. R., Detera-Wadleigh, S. D., Etain, B., Falkai, P., Frisén, L., Frye, M. A., Fullerton, J., Gard, S., Garnham, J., Goes, F. S., Grof, P., Gruber, O., Hashimoto, R., Hauser, J., Heilbronner, U., Hoban, R., Hou, L., Jamain, S., Kahn, J. P., Kassem, L., Kato, T., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., Kuo, P. H., Kusumi, I., Laje, G., Lavebratt, C., Leboyer, M., Leckband, S. G., López Jaramillo, C. A., Maj, M., Malafosse, A., Martinsson, L., Masui, T., Mitchell, P. B., Mondimore, F., Monteleone, P., Nallet, A., Neuner, M., Novák, T., O'Donovan, C., Ösby, U., Ozaki, N., Perlis, R. H., Pfennig, A., Potash, J. B., Reich-Erkelenz, D., Reif, A., Reininghaus, E., Richardson, S., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schubert, O. K., Schweizer, B., Seemüller, F., Grigoroiu-Serbanescu, M., Severino, G., Seymour, L. R., Slaney, C., Smoller, J. W., Squassina, A., Stamm, T., Steele, J., Stopkova, P., Tighe, S. K., Tortorella, A., Turecki, G., Wray, N. R., Wright, A., Zandi, P. P., Zilles, D., Bauer, M., Rietschel, M., McMahon, F. J., Schulze, T. G. & Alda, M., Jun 19 2013, In : PLoS One. 8, 6, e65636.

Research output: Contribution to journalArticle

lithium
Bipolar Disorder
Lithium
Therapeutics
pharmacogenomics
8 Citations (Scopus)

Association between history of psychosis and cardiovascular disease in bipolar disorder

Prieto, M. L., Mcelroy, S. L., Hayes, S. N., Sutor, B., Kung, S., Bobo, W. V., Fuentes, M. E., Cuellar-Barboza, A. B., Crow, S., Ösby, U., Chauhan, M., Westman, J., Geske, J. R., Colby, C. L., Ryu, E., Biernacka, J. M. & Frye, M. A., Aug 1 2015, In : Bipolar Disorders. 17, 5, p. 518-527 10 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Psychotic Disorders
Cardiovascular Diseases
Odds Ratio
Confidence Intervals
8 Citations (Scopus)

Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with early-onset bipolar disorder

Nassan, M., Croarkin, P. E., Luby, J. L., Veldic, M. D., Joshi, P. T., Mcelroy, S. L., Post, R. M., Walkup, J. T., Cercy, K., Geske, J. R., Wagner, K. D., Cuellar-Barboza, A. B., Casuto, L., Lavebratt, C., Schalling, M., Jensen, P. S., Biernacka, J. M. & Frye, M. A., Sep 1 2015, In : Bipolar Disorders. 17, 6, p. 645-652 8 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Bipolar Disorder
Odds Ratio
Alleles
Age of Onset

Association of Cytomegalovirus and Toxoplasma gondii Antibody Titers with Bipolar Disorder

Frye, M. A., Coombes, B. J., McElroy, S. L., Jones-Brando, L., Bond, D. J., Veldic, M. D., Romo-Nava, F., Bobo, W. V., Singh, B., Colby, C., Skime, M. K., Biernacka, J. M. & Yolken, R., Jan 1 2019, (Accepted/In press) In : JAMA Psychiatry.

Research output: Contribution to journalArticle

Toxoplasma
Cytomegalovirus
Bipolar Disorder
Antibodies
Psychotic Disorders
12 Citations (Scopus)

Association of GATA4 sequence variation with alcohol dependence

Karpyak, V. M., Winham, S. J., Biernacka, J. M., Cunningham, J. M., Lewis, K. A., Geske, J. R., Colby, C. L., Abulseoud, O. A., Hall-Flavin, D. K., Loukianova, L. L., Schneekloth, T. D., Frye, M. A., Heit, J. A. & Mrazek, D. A., Mar 2014, In : Addiction Biology. 19, 2, p. 312-315 4 p.

Research output: Contribution to journalArticle

Alcoholism
Single Nucleotide Polymorphism
Alcohols
Genes
acamprosate
29 Citations (Scopus)

Association of polygenic score for schizophrenia and HLA antigen and inflammation genes with response to lithium in bipolar affective disorder: A genome-wide association study

International Consortium on Lithium Genetics (ConLi+Gen), Jan 1 2018, In : JAMA Psychiatry. 75, 1, p. 65-74 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
HLA Antigens
Mood Disorders
Bipolar Disorder
Lithium
5 Citations (Scopus)

Association of schizophrenia polygenic risk score with manic and depressive psychosis in bipolar disorder

Markota, M., Coombes, B. J., Larrabee, B. R., McElroy, S. L., Bond, D. J., Veldic, M. D., Colby, C. L., Chauhan, M., Cuellar-Barboza, A. B., Fuentes, M., Kung, S., Prieto, M. L., Rummans, T. A., Bobo, W. V., Frye, M. A. & Biernacka, J. M., Dec 1 2018, In : Translational Psychiatry. 8, 1, 188.

Research output: Contribution to journalArticle

Bipolar Disorder
Psychotic Disorders
Schizophrenia
Phenotype
Depression
18 Citations (Scopus)

Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states

Karpyak, V. M., Winham, S. J., Preuss, U. W., Zill, P., Cunningham, J. M., Walker, D. L., Lewis, K. A., Geske, J. R., Colby, C. L., Abulseoud, O. A., Hall-Flavin, D. K., Loukianova, L. L., Schneekloth, T. D., Frye, M. A., Bazov, I., Heit, J. A., Bakalkin, G., Mrazek, D. A. & Biernacka, J. M., Jun 2013, In : International Journal of Neuropsychopharmacology. 16, 5, p. 975-985 11 p.

Research output: Contribution to journalArticle

Alcoholism
Single Nucleotide Polymorphism
Genes
Depression
Haplotypes
3 Citations (Scopus)

Association of the polygenic scores for personality traits and response to selective serotonin reuptake inhibitors in patients with major depressive disorder

Amare, A. T., Schubert, K. O., Tekola-Ayele, F., Hsu, Y. H., Sangkuhl, K., Jenkins, G., Whaley, R. M., Barman, P., Batzler, A., Altman, R. B., Arolt, V., Brockmöller, J., Chen, C. H., Domschke, K., Hall-Flavin, D. K., Hong, C. J., Illi, A., Ji, Y., Kampman, O., Kinoshita, T. & 17 others, Leinonen, E., Liou, Y. J., Mushiroda, T., Nonen, S., Skime, M. K., Wang, L. M., Kato, M., Liu, Y. L., Praphanphoj, V., Stingl, J. C., Bobo, W. V., Tsai, S. J., Kubo, M., Klein, T. E., Weinshilboum, R. M., Biernacka, J. M. & Baune, B. T., Mar 6 2018, In : Frontiers in Psychiatry. 9, MAR, 65.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Personality
Genome-Wide Association Study
Meta-Analysis
1 Citation (Scopus)

Association of the serotonin transporter-linked polymorphic region genotype with lower bone mineral density

Lapid, M. I., Kung, S., Frye, M. A., Biernacka, J. M., Geske, J. R., Drake, M. M., Jankowski, M. D. & Clarke, B., Aug 22 2017, In : Translational Psychiatry. 7, 8, p. e1213

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Bone Density
Alleles
Genotype
Spine
1 Citation (Scopus)

Associations of catechol-O-methyltransferase (rs4680) single nucleotide polymorphisms with opioid use and dose among adults with chronic pain

Hooten, W. M., Biernacka, J. M., OʼBrien, T. G., Cunningham, J. M. & Black, J. L., Jan 1 2019, In : Pain. 160, 1, p. 263-268 6 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Chronic Pain
Opioid Analgesics
Single Nucleotide Polymorphism
Genotype
3 Citations (Scopus)

Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent

Winham, S. J., Preuss, U. W., Geske, J. R., Zill, P., Heit, J. A., Bakalkin, G., Biernacka, J. M. & Karpyak, V. M., Oct 27 2015, In : Scientific Reports. 5, 15670.

Research output: Contribution to journalArticle

Alcoholism
Phenotype
Haplotypes
Recurrence
Substance-Related Disorders
25 Citations (Scopus)
Random Forest
Genes
High-dimensional Data
Gene
Effect Size
11 Citations (Scopus)

Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: Metabolomics-informed genomics

Liu, D., Ray, B., Neavin, D. R., Zhang, J., Athreya, A. P., Biernacka, J. M., Bobo, W. V., Hall-Flavin, D. K., Skime, M. K., Zhu, H., Jenkins, G. D., Batzler, A., Kalari, K. R., Boakye-Agyeman, F., Matson, W. R., Bhasin, S. S., Mushiroda, T., Nakamura, Y., Kubo, M., Iyer, R. K. & 4 others, Wang, L. M., Frye, M. A., Kaddurah-Daouk, R. & Weinshilboum, R. M., Dec 1 2018, In : Translational Psychiatry. 8, 1, 56.

Research output: Contribution to journalArticle

beta-Defensins
Kynurenine
Aryl Hydrocarbon Receptors
Metabolomics
Major Depressive Disorder
5 Citations (Scopus)

Bipolar disorder with binge eating behavior: A genome-wide association study implicates PRR5-ARHGAP8

McElroy, S. L., Winham, S. J., Cuellar-Barboza, A. B., Colby, C. L., Ho, A. M. C., Sicotte, H., Larrabee, B. R., Crow, S., Frye, M. A. & Biernacka, J. M., Dec 1 2018, In : Translational Psychiatry. 8, 1, 40.

Research output: Contribution to journalArticle

Bulimia
Genome-Wide Association Study
Feeding Behavior
Bipolar Disorder
Risk-Taking
21 Citations (Scopus)

Bipolar disorder with comorbid binge eating history: A genome-wide association study implicates APOB

Winham, S. J., Cuellar-Barboza, A. B., McElroy, S. L., Oliveros, A., Crow, S., Colby, C. L., Choi, D. S., Chauhan, M., Frye, M. A. & Biernacka, J. M., Aug 20 2014, In : Journal of Affective Disorders. 165, p. 151-158 8 p.

Research output: Contribution to journalArticle

Bulimia
Genome-Wide Association Study
Bipolar Disorder
Single Nucleotide Polymorphism
History
21 Citations (Scopus)

Catechol O-methyltransferase pharmacogenomics and selective serotonin reuptake inhibitor response

Ji, Y., Biernacka, J. M., Snyder, K., Drews, M., Pelleymounter, L. L., Colby, C., Wang, L. M., Mrazek, D. A. & Weinshilboum, R. M., 2012, In : Pharmacogenomics Journal. 12, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

Catechol O-Methyltransferase
Pharmacogenetics
Serotonin Uptake Inhibitors
Citalopram
Single Nucleotide Polymorphism
10 Citations (Scopus)

Clinical features of bipolar spectrum with binge eating behaviour

McElroy, S. L., Crow, S., Blom, T. J., Cuellar-Barboza, A. B., Prieto, M. L., Veldic, M. D., Winham, S. J., Bobo, W. V., Geske, J., Seymour, L. R., Mori, N., Bond, D. J., Biernacka, J. M. & Frye, M. A., Sep 1 2016, In : Journal of Affective Disorders. 201, p. 95-98 4 p.

Research output: Contribution to journalArticle

Bulimia
Feeding Behavior
Cost of Illness
Bipolar Disorder
Comorbidity

Clinical phenotype and genetic risk factors for bipolar disorder with binge eating: an update

Cuellar-Barboza, A. B., Winham, S. J., Biernacka, J. M., Frye, M. A. & McElroy, S. L., Sep 1 2019, In : Expert review of neurotherapeutics. 19, 9, p. 867-879 13 p.

Research output: Contribution to journalArticle

Bulimia
Bipolar Disorder
Phenotype
Psychiatry
Binge-Eating Disorder
34 Citations (Scopus)

Clinical phenotype of bipolar disorder with comorbid binge eating disorder

McElroy, S. L., Crow, S., Biernacka, J. M., Winham, S. J., Geske, J., Barboza, A. B. C., Prieto, M. L., Chauhan, M., Seymour, L. R., Mori, N. & Frye, M. A., Sep 25 2013, In : Journal of Affective Disorders. 150, 3, p. 981-986 6 p.

Research output: Contribution to journalArticle

Binge-Eating Disorder
Bipolar Disorder
Phenotype
Obesity
Cost of Illness
13 Citations (Scopus)

Clinical risk factors and serotonin transporter gene variants associated with antidepressant-induced mania

Frye, M. A., McElroy, S. L., Prieto, M. L., Harper, K. L., Walker, D. L., Kung, S., Chauhan, M., Crow, S., Sutor, B., Galardy, C. W., Veldic, M. D., Palmer, B. A., Geske, J. R., Fuentes, M., Cuellar-Barboza, A. B., Seymour, L. R., Mori, N. & Biernacka, J. M., Feb 1 2015, In : The Journal of clinical psychiatry. 76, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Bipolar Disorder
Antidepressive Agents
Genes
Haplotypes
24 Citations (Scopus)

Common variants in PARK loci and related genes and Parkinson's disease

Chung, S. J., Armasu, S. M., Biernacka, J. M., Lesnick, T. G., Rider, D. N., Lincoln, S. J., Ortolaza, A. I., Farrer, M. J., Cunningham, J. M., Rocca, W. A. & Maraganore, D. M., Feb 1 2011, In : Movement Disorders. 26, 2, p. 280-288 9 p.

Research output: Contribution to journalArticle

Parkinson Disease
Disease Susceptibility
Single Nucleotide Polymorphism
Genes
Age of Onset
4 Citations (Scopus)

Comparison of family-based association tests in chromosome regions selected by linkage-based confidence intervals

Lewinger, J. P., Lee, S. S. F., Biernacka, J. M., Wu, L. Y., Shi, H. S. & Bull, S. B., Dec 30 2005, In : BMC Genetics. 6, SUPPL.1, S62.

Research output: Contribution to journalArticle

Chromosomes
Confidence Intervals
Single Nucleotide Polymorphism
Software
Genome
343 Citations (Scopus)

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDgene database

Lill, C. M., Roehr, J. T., McQueen, M. B., Kavvoura, F. K., Bagade, S., Schjeide, B. M. M., Schjeide, L. M., Meissner, E., Zauft, U., Allen, N. C., Liu, T., Schilling, M., Anderson, K. J., Beecham, G., Berg, D., Biernacka, J. M., Brice, A., DeStefano, A. L., Do, C. B., Eriksson, N. & 34 others, Factor, S. A., Farrer, M. J., Foroud, T., Gasser, T., Hamza, T., Hardy, J. A., Heutink, P., Hill-Burns, E. M., Klein, C., Latourelle, J. C., Maraganore, D. M., Martin, E. R., Martinez, M., Myers, R. H., Nalls, M. A., Pankratz, N., Payami, H., Satake, W., Scott, W. K., Sharma, M., Singleton, A. B., Stefansson, K., Toda, T., Tung, J. Y., Vance, J., Wood, N. W., Zabetian, C. P., Young, P., Tanzi, R. E., Khoury, M. J., Zipp, F., Lehrach, H., Ioannidis, J. P. A. & Bertram, L., Mar 2012, In : PLoS Genetics. 8, 3, e1002548.

Research output: Contribution to journalArticle

Parkinson disease
Parkinson Disease
Meta-Analysis
Genome-Wide Association Study
genome
23 Citations (Scopus)

Current landscape, unmet needs, and future directions for treatment of bipolar depression

Frye, M. A., Prieto, M. L., Bobo, W. V., Kung, S., Veldic, M. D., Alarcon, R. D., Moore, K. M., Choi, D. S., Biernacka, J. M. & Tye, S. J., Dec 1 2014, In : Journal of Affective Disorders. 169, S1, p. S17-S23

Research output: Contribution to journalArticle

Bipolar Disorder
Precision Medicine
Therapeutics
Antidepressive Agents
Direction compound
82 Citations (Scopus)

CYP2C19 variation and citalopram response

Mrazek, D. A., Biernacka, J. M., O'Kane, D. J., Black, J. L., Cunningham, J. M., Drews, M. S., Snyder, K. A., Stevens, S. R., Rush, A. J. & Weinshilboum, R. M., Jan 2011, In : Pharmacogenetics and Genomics. 21, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Citalopram
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Genotype
Depression

Cytochrome P450 2C19 poor metabolizer phenotype in treatment resistant depression: Treatment and diagnostic implications

Veldic, M. D., Ahmed, A. T., Blacker, C. J., Geske, J. R., Biernacka, J. M., Borreggine, K. L., Moore, K. M., Prieto, M. L., Vande Voort, J., Croarkin, P. E., Hoberg, A. A., Kung, S., Alarcon, R. D., Keeth, N., Singh, B., Bobo, W. V. & Frye, M. A., Jan 1 2019, In : Frontiers in Pharmacology. 10, FEB, 83.

Research output: Contribution to journalArticle

Open Access
Treatment-Resistant Depressive Disorder
Cytochrome P-450 Enzyme System
Phenotype
Bipolar Disorder
Major Depressive Disorder

Decreased core symptoms of mania and utilization of lithium/mood stabilizing anticonvulsants in U.S. bipolar I patients of African vs European ancestry

Akinhanmi, M., El-Amin, S., Balls-Berry, J., Vallender, E. J., Ladner, M., Geske, J., Coombes, B., Biernacka, J. M., Kelsoe, J. & Frye, M. A., Jan 1 2020, In : Journal of Affective Disorders. 260, p. 361-365 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Lithium
Anticonvulsants
Hallucinations
Interviews
22 Citations (Scopus)

Development of a bipolar disorder biobank: differential phenotyping for subsequent biomarker analyses

Frye, M. A., McElroy, S. L., Fuentes, M., Sutor, B., Schak, K. M., Galardy, C. W., Palmer, B. A., Prieto, M. L., Kung, S., Sola, C. L., Ryu, E., Veldic, M. D., Geske, J., Cuellar-Barboza, A., Seymour, L. R., Mori, N., Crowe, S., Rummans, T. A. & Biernacka, J. M., Dec 30 2015, In : International Journal of Bipolar Disorders. 3, 1, 14.

Research output: Contribution to journalArticle

Bipolar Disorder
Biomarkers
Demography
Phenotype
Exanthema
6 Citations (Scopus)

Differential SLC1A2 promoter methylation in bipolar disorder with or without addiction

Jia, Y. F., Choi, Y. B., Ayers-Ringler, J. R., Biernacka, J. M., Geske, J. R., Lindberg, D. R., McElroy, S. L., Frye, M. A., Choi, D. S. & Veldic, M. D., Jul 21 2017, In : Frontiers in Cellular Neuroscience. 11, 217.

Research output: Contribution to journalArticle

Bipolar Disorder
Methylation
Excitatory Amino Acid Transporter 2
Nicotine
Genetic Promoter Regions
1 Citation (Scopus)

Does simultaneous consideration of multiple regions improve disease gene localization?

Biernacka, J. M., Lewinger, J. P., Chan, V. & Bull, S. B., 2001, In : Genetic Epidemiology. 21, SUPPL. 1

Research output: Contribution to journalArticle

Genes
Disease Susceptibility
Nuclear Family
Alleles
Weights and Measures
18 Citations (Scopus)

Does α-synuclein have a dual and opposing effect in preclinical vs. clinical Parkinson's disease?

Markopoulou, K., Biernacka, J. M., Armasu, S. M., Anderson, K. J., Ahlskog, J. E., Chase, B. A., Chung, S. J., Cunningham, J. M., Farrer, M., Frigerio, R. & Maraganore, D. M., 2014, In : Parkinsonism and Related Disorders. 20, 6, p. 584-589 6 p.

Research output: Contribution to journalArticle

Synucleins
Parkinson Disease
Genotype
Alzheimer Disease
Interviews
19 Citations (Scopus)

Do interactions between SNCA, MAPT, and LRRK2 genes contribute to Parkinson's disease susceptibility?

Biernacka, J. M., Armasu, S. M., Cunningham, J. M., Eric Ahlskog, J., Chung, S. J. & Maraganore, D. M., Dec 2011, In : Parkinsonism and Related Disorders. 17, 10, p. 730-736 7 p.

Research output: Contribution to journalArticle

Disease Susceptibility
Single Nucleotide Polymorphism
Parkinson Disease
Minisatellite Repeats
Genes
4 Citations (Scopus)

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S. H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M., Farmer, A. & 7 others, Aitchison, K. J., Craig, I., McGuffin, P., Schruers, K., Biernacka, J. M., Uher, R. & Lewis, C. M., Aug 1 2018, In : European Neuropsychopharmacology. 28, 8, p. 945-954 10 p.

Research output: Contribution to journalArticle

Citalopram
Genome-Wide Association Study
Cytochromes
Antidepressive Agents
Meta-Analysis
44 Citations (Scopus)

Effect of cytochrome P450 enzyme polymorphisms on pharmacokinetics of venlafaxine

McAlpine, D. E., Biernacka, J. M., Mrazek, D. A., O'Kane, D. J., Stevens, S. R., Langman, L. J., Courson, V. L., Bhagia, J. & Moyer, T. P., Feb 2011, In : Therapeutic Drug Monitoring. 33, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

Cytochrome P-450 Enzyme System
Pharmacokinetics
Cytochrome P-450 CYP2D6
Genotype
Venlafaxine Hydrochloride
15 Citations (Scopus)

Elevated baseline serum glutamate as a pharmacometabolomic biomarker for Acamprosate treatment outcome in alcohol-dependent subjects

Nam, H. W., Karpyak, V. M., Hinton, D. J., Geske, J. R., Ho, A. M. C., Prieto, M. L., Biernacka, J. M., Frye, M. A., Weinshilboum, R. M. & Choi, D. S., 2015, In : Translational Psychiatry. 5, 8, 120.

Research output: Contribution to journalArticle

Glutamic Acid
Biomarkers
Alcohols
Serum
acamprosate
5 Citations (Scopus)

Elevated Glutamate Levels in the Left Dorsolateral Prefrontal Cortex Are Associated with Higher Cravings for Alcohol

Frye, M. A., Hinton, D. J., Karpyak, V. M., Biernacka, J. M., Gunderson, L. J., Geske, J., Feeder, S. E., Choi, D. S. & Port, J. D., Aug 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 8, p. 1609-1616 8 p.

Research output: Contribution to journalArticle

Prefrontal Cortex
Glutamic Acid
Alcohols
Cerebrospinal fluid
Aspartic Acid
Psychopharmacology
Pharmacogenetics
Antidepressive Agents
Depression
Research
10 Citations (Scopus)

Exploring causality via identification of SNPs or haplotypes responsible for a linkage signal

Biernacka, J. M. & Cordell, H. J., Nov 2007, In : Genetic Epidemiology. 31, 7, p. 727-740 14 p.

Research output: Contribution to journalArticle

Causality
Haplotypes
Single Nucleotide Polymorphism
Linkage Disequilibrium
Viverridae