• 3133 Citations
  • 29 Scopus h-Index
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Research Output 2001 2020

  • 3133 Citations
  • 29 Scopus h-Index
  • 134 Article
  • 1 Letter
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Article
10 Citations (Scopus)

Exploring causality via identification of SNPs or haplotypes responsible for a linkage signal

Biernacka, J. M. & Cordell, H. J., Nov 2007, In : Genetic Epidemiology. 31, 7, p. 727-740 14 p.

Research output: Contribution to journalArticle

Causality
Haplotypes
Single Nucleotide Polymorphism
Linkage Disequilibrium
Viverridae
2 Citations (Scopus)

Exploring hepsin functional genetic variation association with disease specific protein expression in bipolar disorder: Applications of a proteomic informed genomic approach

Nassan, M., Jia, Y. F., Jenkins, G., Colby, C., Feeder, S., Choi, D. S., Veldic, M. D., McElroy, S. L., Bond, D. J., Weinshilboum, R. M., Biernacka, J. M. & Frye, M. A., Dec 1 2017, In : Journal of Psychiatric Research. 95, p. 208-212 5 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Proteomics
Quantitative Trait Loci
Alleles
Proteins

Factor analysis of the eating disorder diagnostic scale in individuals with bipolar disorder

Crow, S., Blom, T. J., Sim, L., Cuellar-Barboza, A. B., Biernacka, J. M., Frye, M. A. & McElroy, S. L., Apr 1 2019, In : Eating Behaviors. 33, p. 30-33 4 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Statistical Factor Analysis
Bulimia
Feeding Behavior
Psychopathology
5 Citations (Scopus)

Feasibility of investigating differential proteomic expression in depression: Implications for biomarker development in mood disorders

Frye, M. A., Nassan, M., Jenkins, G. D., Kung, S., Veldic, M. D., Palmer, B. A., Feeder, S. E., Tye, S. J., Choi, D. S. & Biernacka, J. M., Dec 1 2015, In : Translational Psychiatry. 5, e687.

Research output: Contribution to journalArticle

Growth Differentiation Factor 15
Mood Disorders
Proteomics
Matrix Metalloproteinase 7
Bipolar Disorder
18 Citations (Scopus)

Feasibility of investigating differential proteomic expression in depression: implications for biomarker development in mood disorders

Frye, M. A., Nassan, M., Jenkins, G. D., Kung, S., Veldic, M. D., Palmer, B. A., Feeder, S. E., Tye, S. J., Choi, D. S. & Biernacka, J. M., 2015, In : Translational Psychiatry. 5, p. e689

Research output: Contribution to journalArticle

Growth Differentiation Factor 15
Mood Disorders
Proteomics
Matrix Metalloproteinase 7
Bipolar Disorder
42 Citations (Scopus)

FKBP5 genetic variation: Association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder

Ellsworth, K. A., Moon, I., Eckloff, B. W., Fridley, B. L., Jenkins, G. D., Batzler, A., Biernacka, J. M., Abo, R., Brisbin, A., Ji, Y., Hebbring, S., Wieben, E. D., Mrazek, D. A., Weinshilboum, R. M. & Wang, L. M., Mar 2013, In : Pharmacogenetics and Genomics. 23, 3, p. 156-166 11 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Single Nucleotide Polymorphism
DNA
Odds Ratio
28 Citations (Scopus)

Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures

Kim, J. H., Karpyak, V. M., Biernacka, J. M., Nam, H. W., Lee, M. R., Preuss, U. W., Zill, P., Yoon, G., Colby, C., Mrazek, D. A. & Choi, D. S., 2011, In : PLoS One. 6, 1, e16331.

Research output: Contribution to journalArticle

Alcohol Withdrawal Seizures
adenosine
alcohol abuse
seizures
Adenosine
24 Citations (Scopus)

Gender differences in the relationship between depressive symptoms and cravings in alcoholism

Boykoff, N., Schneekloth, T. D., Hall-Flavin, D., Loukianova, L., Karpyak, V. M., Stevens, S. R., Biernacka, J. M., Mrazek, D. A. & Frye, M. A., 2010, In : American Journal on Addictions. 19, 4, p. 352-356 5 p.

Research output: Contribution to journalArticle

Alcoholism
Alcohols
Depression
Dual (Psychiatry) Diagnosis
Prospective Studies
16 Citations (Scopus)

Gender-specific effects of comorbid depression and anxiety on the propensity to drink in negative emotional states

Karpyak, V. M., Biernacka, J. M., Geske, J. R., Abulseoud, O. A., Brunner, M. D., Chauhan, M., Hall-Flavin, D. K., Lewis, K. A., Loukianova, L. L., Melnyk, G. J., Onsrud, D. A., Proctor, B. D., Schneekloth, T. D., Skime, M. K., Wittkopp, J. E., Frye, M. A. & Mrazek, D. A., 2016, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Anxiety
Depression
Anxiety Disorders
Major Depressive Disorder
Alcoholism
28 Citations (Scopus)
Gene-Environment Interaction
Genome-Wide Association Study
Psychiatry
Genome
Genes
95 Citations (Scopus)

Gene set analysis of SNP data: Benefits, challenges, and future directions

Fridley, B. L. & Biernacka, J. M., Aug 2011, In : European Journal of Human Genetics. 19, 8, p. 837-843 7 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Genes
Genome-Wide Association Study
Phenotype
Genetic Research
33 Citations (Scopus)

Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate

Karpyak, V. M., Biernacka, J. M., Geske, J. R., Jenkins, G. D., Cunningham, J. M., Rüegg, J., Kononenko, O., Leontovich, A. A., Abulseoud, O. A., Hall-Flavin, D. K., Loukianova, L. L., Schneekloth, T. D., Skime, M. K., Frank, J., Nöthen, M. M., Rietschel, M., Kiefer, F., Mann, K. F., Weinshilboum, R. M., Frye, M. A. & 1 others, Choi, D. S., 2014, In : Translational Psychiatry. 4, p. e462

Research output: Contribution to journalArticle

Genetic Markers
Alcohols
Linkage Disequilibrium
Statistical Models
Alcoholics
5 Citations (Scopus)

Genetic risk score analysis in early-onset bipolar disorder

Croarkin, P. E., Luby, J. L., Cercy, K., Geske, J. R., Veldic, M. D., Simonson, M., Joshi, P. T., Wagner, K. D., Walkup, J. T., Nassan, M. M., Cuellar-Barboza, A. B., Casuto, L., McElroy, S. L., Jensen, P. S., Frye, M. A. & Biernacka, J. M., Nov 1 2017, In : Journal of Clinical Psychiatry. 78, 9, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Single Nucleotide Polymorphism
Ankyrins
Haplotypes
Ranvier's Nodes
15 Citations (Scopus)

Genetic susceptibility loci, environmental exposures, and Parkinson's disease: A case-control study of gene-environment interactions

Chung, S. J., Armasu, S. M., Anderson, K. J., Biernacka, J. M., Lesnick, T. G., Rider, D. N., Cunningham, J. M., Ahlskog, J. E., Frigerio, R. & Maraganore, D. M., Jun 2013, In : Parkinsonism and Related Disorders. 19, 6, p. 595-599 5 p.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Genetic Loci
Environmental Exposure
Genetic Predisposition to Disease
Parkinson Disease
18 Citations (Scopus)

Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence

Karpyak, V. M., Geske, J. R., Colby, C. L., Mrazek, D. A. & Biernacka, J. M., Jul 2012, In : Addiction Biology. 17, 4, p. 798-806 9 p.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
N-Methylaspartate
Alcoholism
Single Nucleotide Polymorphism
Genes
2 Citations (Scopus)

Genetic variant in SLC1A2 is associated with elevated anterior cingulate cortex glutamate and lifetime history of rapid cycling

Veldic, M. D., Millischer, V., Port, J. D., Ho, A. M. C., Jia, Y. F., Geske, J. R., Biernacka, J. M., Backlund, L., McElroy, S. L., Bond, D. J., Villaescusa, J. C., Skime, M., Choi, D. S., Lavebratt, C., Schalling, M. & Frye, M. A., Dec 1 2019, In : Translational psychiatry. 9, 1, 149.

Research output: Contribution to journalArticle

Open Access
Gyrus Cinguli
Glutamic Acid
Alleles
Single Nucleotide Polymorphism
Mood Disorders
104 Citations (Scopus)

Genetic variants associated with response to lithium treatment in bipolar disorder: A genome-wide association study

Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N., Ardau, R., Arias, B., Backlund, L., Banzato, C. E. M., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Bui, E. T., Cervantes, P., Chen, G. B., Chen, H. C. & 103 others, Chillotti, C., Cichon, S., Clark, S. R., Colom, F., Cousins, D. A., Cruceanu, C., Czerski, P. M., Dantas, C. R., Dayer, A., Étain, B., Falkai, P., Forstner, A. J., Frisén, L., Fullerton, J. M., Gard, S., Garnham, J. S., Goes, F. S., Grof, P., Gruber, O., Hashimoto, R., Hauser, J., Herms, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Lackner, N., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Jaramillo, C. A. L., Macqueen, G., Manchia, M., Martinsson, L., Mattheisen, M., McCarthy, M. J., McElroy, S. L., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Ösby, U., Ozaki, N., Perlis, R. H., Pfennig, A., Reich-Erkelenz, D., Rouleau, G. A., Schofield, P. R., Schubert, K. O., Schweizer, B. W., Seemüller, F., Severino, G., Shekhtman, T., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Smoller, J. W., Squassina, A., Stamm, T., Stopkova, P., Tighe, S. K., Tortorella, A., Turecki, G., Volkert, J., Witt, S., Wright, A., Young, L. T., Zandi, P. P., Potash, J. B., Depaulo, J. R., Bauer, M., Reininghaus, E. Z., Novák, T., Aubry, J. M., Maj, M., Baune, B. T., Mitchell, P. B., Vieta, E., Frye, M. A., Rybakowski, J. K., Kuo, P. H., Kato, T., Grigoroiu-Serbanescu, M., Reif, A., Del Zompo, M., Bellivier, F., Schalling, M., Wray, N. R., Kelsoe, J. R., Alda, M., Rietschel, M., McMahon, F. J. & Schulze, T. G., Mar 12 2016, In : The Lancet. 387, 10023, p. 1085-1093 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Lithium
Single Nucleotide Polymorphism
Therapeutics
9 Citations (Scopus)

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Pottier, C., Ren, Y., Perkerson, R. B., Baker, M., Jenkins, G. D., van Blitterswijk, M., DeJesus-Hernandez, M., van Rooij, J. G. J., Murray, M. E., Christopher, E., McDonnell, S. K., Fogarty, Z., Batzler, A., Tian, S., Vicente, C. T., Matchett, B., Karydas, A. M., Hsiung, G. Y. R., Seelaar, H., Mol, M. O. & 85 others, Finger, E. C., Graff, C., Öijerstedt, L., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Prudlo, J., Rizzu, P., Simon-Sanchez, J., Edbauer, D., Roeber, S., Diehl-Schmid, J., Evers, B. M., King, A., Mesulam, M. M., Weintraub, S., Geula, C., Bieniek, K. F., Petrucelli, L., Ahern, G. L., Reiman, E. M., Woodruff, B. K., Caselli, R. J., Huey, E. D., Farlow, M. R., Grafman, J., Mead, S., Grinberg, L. T., Spina, S., Grossman, M., Irwin, D. J., Lee, E. B., Suh, E. R., Snowden, J., Mann, D., Ertekin-Taner, N., Uitti, R. J., Wszolek, Z. K., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Hodges, J. R., Piguet, O., Geier, E. G., Yokoyama, J. S., Rissman, R. A., Rogaeva, E., Keith, J., Zinman, L., Tartaglia, M. C., Cairns, N. J., Cruchaga, C., Ghetti, B., Kofler, J., Lopez, O. L., Beach, T. G., Arzberger, T., Herms, J., Honig, L. S., Vonsattel, J. P., Halliday, G. M., Kwok, J. B., White, C. L., Gearing, M., Glass, J., Rollinson, S., Pickering-Brown, S., Rohrer, J. D., Trojanowski, J. Q., Van Deerlin, V., Bigio, E. H., Troakes, C., Al-Sarraj, S., Asmann, Y., Miller, B. L., Graff-Radford, N. R., Boeve, B. F., Seeley, W. W., Mackenzie, I. R. A., van Swieten, J. C., Dickson, D. W., Biernacka, J. M. & Rademakers, R., Jan 1 2019, In : Acta neuropathologica.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Frontotemporal Dementia
Genome
Genes
Mutation
58 Citations (Scopus)

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In : Nature Genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Genome
Neurotransmitter Transport Proteins
Endocannabinoids
55 Citations (Scopus)

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Hou, L., Bergen, S. E., Akula, N., Song, J., Hultman, C. M., Landén, M., Adli, M., Alda, M., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Badner, J. A., Barrett, T. B., Bauer, M., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S., Berrettini, W. H. & 119 others, Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Bloss, C. S., Brichant-Petitjean, C., Bui, E. T., Byerley, W., Cervantes, P., Chillotti, C., Cichon, S., Colom, F., Coryell, W., Craig, D. W., Cruceanu, C., Czerski, P. M., Davis, T., Dayer, A., Degenhardt, F., Del Zompo, M., DePaulo, J. R., Edenberg, H. J., Étain, B., Falkai, P., Foroud, T., Forstner, A. J., Frisén, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Gershon, E. S., Goes, F. S., Greenwood, T. A., Grigoroiu-Serbanescu, M., Hauser, J., Heilbronner, U., Heilmann-Heimbach, S., Herms, S., Hipolito, M., Hitturlingappa, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., Koller, D. L., König, B., Lackner, N., Laje, G., Lang, M., Lavebratt, C., Lawson, W. B., Leboyer, M., Leckband, S. G., Liu, C., Maaser, A., Mahon, P. B., Maier, W., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McInnis, M. G., McKinney, R., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Mühleisen, T. W., Nievergelt, C. M., Nöthen, M. M., Novák, T., Nurnberger, J. I., Nwulia, E. A., Ösby, U., Pfennig, A., Potash, J. B., Propping, P., Reif, A., Reininghaus, E., Rice, J., Rietschel, M., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scheftner, W. A., Schofield, P. R., Schork, N. J., Schulze, T. G., Schumacher, J., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Smith, E. N., Squassina, A., Stamm, T., Stopkova, P., Streit, F., Strohmaier, J., Szelinger, S., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Volkert, J., Witt, S. H., Wright, A., Zandi, P. P., Zhang, P., Zollner, S. & McMahon, F. J., 2015, In : Human Molecular Genetics. 25, 15, p. 3383-3394 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
X Chromosome
Lithium
Odds Ratio
43 Citations (Scopus)

Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2

Winham, S. J., Cuellar-Barboza, A. B., Oliveros, A., McElroy, S. L., Crow, S., Colby, C., Choi, D. S., Chauhan, M., Frye, M. A. & Biernacka, J. M., Dec 10 2013, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Body Mass Index
Alleles
Single Nucleotide Polymorphism
35 Citations (Scopus)

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorders Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 20 2017, In : Translational Psychiatry. 7, 6, p. e1155

Research output: Contribution to journalArticle

Borderline Personality Disorder
Genome-Wide Association Study
Bipolar Disorder
Schizophrenia
Depression
12 Citations (Scopus)

Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease

Biernacka, J. M., Chung, S. J., Armasu, S. M., Anderson, K. S., Lill, C. M., Bertram, L., Ahlskog, J. E., Brighina, L., Frigerio, R. & Maraganore, D. M., Nov 1 2016, In : Parkinsonism and Related Disorders. 32, p. 25-30 6 p.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Pesticides
Parkinson Disease
Genome
Genes
21 Citations (Scopus)

Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence

Biernacka, J. M., Geske, J., Jenkins, G. D., Colby, C., Rider, D. N., Karpyak, V. M., Choi, D. S. & Fridley, B. L., Mar 2013, In : International Journal of Neuropsychopharmacology. 16, 2, p. 271-278 8 p.

Research output: Contribution to journalArticle

Alcoholism
Genome
Genes
Single Nucleotide Polymorphism
Encyclopedias
16 Citations (Scopus)

Genomic determinants of motor and cognitive outcomes in Parkinson's disease

Chung, S. J., Armasu, S. M., Biernacka, J. M., Anderson, K. J., Lesnick, T. G., Rider, D. N., Cunningham, J. M., Eric Ahlskog, J., Frigerio, R. & Maraganore, D. M., Aug 2012, In : Parkinsonism and Related Disorders. 18, 7, p. 881-886 6 p.

Research output: Contribution to journalArticle

Parkinson Disease
Single Nucleotide Polymorphism
Genes
Genome-Wide Association Study
Proportional Hazards Models
77 Citations (Scopus)

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, Psychosis Endophenotypes International Consortium & Wellcome Trust Case-Control Consortium, Jun 14 2018, In : Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journalArticle

Dissection
Bipolar Disorder
Schizophrenia
Genes
Potassium
118 Citations (Scopus)

Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: Pharmacometabolomics-informed pharmacogenomics

Ji, Y., Hebbring, S., Zhu, H., Jenkins, G. D., Biernacka, J. M., Snyder, K., Drews, M., Fiehn, O., Zeng, Z., Schaid, D. J., Mrazek, D. A., Kaddurah-Daouk, R. & Weinshilboum, R. M., Jan 2011, In : Clinical Pharmacology and Therapeutics. 89, 1, p. 97-104 8 p.

Research output: Contribution to journalArticle

Glycine Dehydrogenase
Citalopram
Pharmacogenetics
Serotonin Uptake Inhibitors
Glycine
6 Citations (Scopus)

GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Jan 1 2019, In : American Journal of Psychiatry. 176, 8, p. 651-660 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Suicide
Psychiatry
Depression
Major Depressive Disorder
133 Citations (Scopus)

Heterozygosity for a POMC-null mutation and increased obesity risk in humans

Farooqi, I. S., Drop, S., Clements, A., Keogh, J. M., Biernacka, J. M., Lowenbein, S., Challis, B. G. & O'Rahilly, S., Sep 2006, In : Diabetes. 55, 9, p. 2549-2553 5 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Obesity
Mutation
Heterozygote
Adrenal Insufficiency

Identification of missing variants by combining multiple analytic pipelines

Ren, Y., Reddy, J. S., Pottier, C., Sarangi, V., Tian, S., Sinnwell, J. P., McDonnell, S. K., Biernacka, J. M., Carrasquillo, M. M., Ross, O. A., Taner, N., Rademakers, R. V., Hudson, M., Mainzer, L. S. & Asmann, Y., Apr 16 2018, In : BMC Bioinformatics. 19, 1, 139.

Research output: Contribution to journalArticle

Sample Size
Pipelines
Gene Frequency
Alzheimer Disease
Sequencing
8 Citations (Scopus)

Integrative gene set analysis: Application to platinum pharmacogenomics

Fridley, B. L., Abo, R., Tan, X. L., Jenkins, G. D., Batzler, A., Moyer, A., Biernacka, J. M. & Wang, L. M., Jan 1 2014, In : OMICS A Journal of Integrative Biology. 18, 1, p. 34-41 8 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Platinum
Genes
DNA Copy Number Variations
Cells
17 Citations (Scopus)

Interaction of SLC6A4 and DRD2 polymorphisms is associated with a history of delirium tremens

Karpyak, V. M., Biernacka, J. M., Weg, M. W. V., Stevens, S. R., Cunningham, J. M., Mrazek, D. A. & Black, J. L., Jan 2010, In : Addiction Biology. 15, 1, p. 23-34 12 p.

Research output: Contribution to journalArticle

Alcohol Withdrawal Delirium
Alcohol Withdrawal Seizures
Logistic Models
Genetic Polymorphisms
Alcoholics
5 Citations (Scopus)

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study

Kalman, J. L., Papiol, S., Forstner, A. J., Heilbronner, U., Degenhardt, F., Strohmaier, J., Adli, M., Adorjan, K., Akula, N., Alda, M., Anderson-Schmidt, H., Andlauer, T. F. M., Anghelescu, I. G., Ardau, R., Arias, B., Arolt, V., Aubry, J. M., Backlund, L., Bartholdi, K., Bauer, M. & 123 others, Baune, B. T., Becker, T., Bellivier, F., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Budde, M., Cervantes, P., Chillotti, C., Cichon, S., Clark, S. R., Colom, F., Comes, A. L., Cruceanu, C., Czerski, P. M., Dannlowski, U., Dayer, A., Del Zompo, M., DePaulo, J. R., Dietrich, D. E., Étain, B., Ethofer, T., Falkai, P., Fallgatter, A., Figge, C., Flatau, L., Folkerts, H., Frisen, L., Frye, M. A., Fullerton, J. M., Gade, K., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Gryaznova, A., Hake, M., Hauser, J., Herms, S., Hoffmann, P., Hou, L., Jäger, M., Jamain, S., Jiménez, E., Juckel, G., Kahn, J. P., Kassem, L., Kelsoe, J., Kittel-Schneider, S., Kliwicki, S., Klohn-Sagatholislam, F., Koller, M., König, B., Konrad, C., Lackner, N., Laje, G., Landén, M., Lang, F. U., Lavebratt, C., Leboyer, M., Leckband, S. G., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McMahon, F. J., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Nieratschker, V., Nievergelt, C. M., Novák, T., Ösby, U., Pfennig, A., Potash, J. B., Reich-Erkelenz, D., Reif, A., Reimer, J., Reininghaus, E., Reitt, M., Ripke, S., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scherk, H., Schmauß, M., Schofield, P. R., Schubert, K. O., Schulte, E. C., Schulz, S., Senner, F., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Spitzer, C., Squassina, A., Stamm, T., Stegmaier, S., Stierl, S., Stopkova, P., Thiel, A., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Veeh, J., von Hagen, M., Wigand, M. E., Wiltfang, J., Witt, S., Wright, A., Zandi, P. P., Zimmermann, J., Nöthen, M., Rietschel, M. & Schulze, T. G., Feb 1 2019, In : Bipolar disorders. 21, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

Open Access
Bipolar Disorder
Age of Onset
Schizophrenia
Public Opinion
Genomics
19 Citations (Scopus)

Lack of Replication of the GRIN2A-by-Coffee Interaction in Parkinson Disease

Ahmed, I., Lee, P. C., Lill, C. M., Searles Nielsen, S., Artaud, F., Gallagher, L. G., Loriot, M. A., Mulot, C., Nacfer, M., Liu, T., Biernacka, J. M., Armasu, S., Anderson, K., Farin, F. M., Funch Lassen, C., Hansen, J., Olsen, J. H., Bertram, L., Maraganore, D. M., Checkoway, H. & 2 others, Ritz, B. & Elbaz, A., Nov 1 2014, In : PLoS Genetics. 10, 11

Research output: Contribution to journalArticle

Gene-Environment Interaction
genotype-environment interaction
Parkinson disease
Genome-Wide Association Study
Coffee
3 Citations (Scopus)

Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities

Prieto, M. L., Ryu, E., Jenkins, G. D., Batzler, A., Nassan, M. M., Cuellar-Barboza, A. B., Pathak, J., McElroy, S. L., Frye, M. A. & Biernacka, J. M., 2016, In : Translational Psychiatry. 6, 8, e870.

Research output: Contribution to journalArticle

Electronic Health Records
Bipolar Disorder
Comorbidity
Single Nucleotide Polymorphism
Odds Ratio
19 Citations (Scopus)

Lipid peroxidation biomarkers in adolescents with or at high-risk for bipolar disorder

Scola, G., McNamara, R. K., Croarkin, P. E., Leffler, J. M., Cullen, K. R., Geske, J. R., Biernacka, J. M., Frye, M. A., Delbello, M. P. & Andreazza, A. C., Mar 1 2016, In : Journal of Affective Disorders. 192, p. 176-183 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Lipid Peroxidation
Biomarkers
Inflammation
Proteins
70 Citations (Scopus)

Machine learning in genome-wide association studies

Szymczak, S., Biernacka, J. M., Cordell, H. J., González-Recio, O., König, I. R., Zhang, H. & Sun, Y. V., 2009, In : Genetic Epidemiology. 33, SUPPL. 1

Research output: Contribution to journalArticle

Genome-Wide Association Study
Single Nucleotide Polymorphism
Genome
Machine Learning
Education
2 Citations (Scopus)

Mapping depression rating scale phenotypes onto research domain criteria (RDoC) to inform biological research in mood disorders

The Mood Disorders Precision Medicine Consortium (MDPMC), Oct 1 2018, In : Journal of Affective Disorders. 238, p. 1-7 7 p.

Research output: Contribution to journalArticle

Mood Disorders
Depression
Phenotype
Research
Anxiety
41 Citations (Scopus)

Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: Selective serotonin reuptake inhibitor response pharmacogenomics

Abo, R., Hebbring, S., Ji, Y., Zhu, H., Zeng, Z. B., Batzler, A., Jenkins, G. D., Biernacka, J. M., Snyder, K., Drews, M., Fiehn, O., Fridley, B., Schaid, D. J., Kamatani, N., Nakamura, Y., Kubo, M., Mushiroda, T., Kaddurah-Daouk, R., Mrazek, D. A. & Weinshilboum, R. M., Apr 2012, In : Pharmacogenetics and Genomics. 22, 4, p. 247-253 7 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Serotonin Uptake Inhibitors
Single Nucleotide Polymorphism
Genome
Citalopram
9 Citations (Scopus)

Metabolomics biomarkers to predict acamprosate treatment response in alcohol-dependent subjects

Hinton, D. J., Vázquez, M. S., Geske, J. R., Hitschfeld, M. J., Ho, A. M. C., Karpyak, V. M., Biernacka, J. M. & Choi, D. S., Dec 1 2017, In : Scientific Reports. 7, 1, 2496.

Research output: Contribution to journalArticle

Metabolomics
Biomarkers
Alcohols
Alcohol Drinking
Therapeutics
4 Citations (Scopus)

Mitochondrial DNA sequence data reveals association of haplogroup U with psychosis in bipolar disorder

Frye, M. A., Ryu, E., Nassan, M., Jenkins, G. D., Andreazza, A. C., Evans, J. M., McElroy, S. L., Oglesbee, D., Highsmith, W. E. J. & Biernacka, J. M., Jan 1 2017, In : Journal of Psychiatric Research. 84, p. 221-226 6 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Bipolar Disorder
Psychotic Disorders
Genes
Phenotype
3 Citations (Scopus)

Modeling X Chromosome Data Using Random Forests: Conquering Sex Bias

Winham, S. J., Jenkins, G. D. & Biernacka, J. M., Feb 1 2016, In : Genetic Epidemiology. 40, 2, p. 123-132 10 p.

Research output: Contribution to journalArticle

Sexism
X Chromosome
Single Nucleotide Polymorphism
Alcoholism
X Chromosome Inactivation

Multivariate generalized linear model for genetic pleiotropy

Schaid, D. J., Tong, X., Batzler, A., Sinnwell, J. P., Qing, J. & Biernacka, J. M., Jan 1 2019, In : Biostatistics (Oxford, England). 20, 1, p. 111-128 18 p.

Research output: Contribution to journalArticle

Generalized Linear Model
Null hypothesis
Null
Gene
Testing
6 Citations (Scopus)

National Survey and Community Advisory Board Development for a Bipolar Disorder Biobank

Frye, M. A., Doederlein, A., Koenig, B., Mcelroy, S. L., Nassan, M., Seymour, L. R., Biernacka, J. M. & Daniels, A. S., Sep 1 2015, In : Bipolar Disorders. 17, 6, p. 598-605 8 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Research
DNA
Informed Consent
Medical Records
10 Citations (Scopus)

New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR∗D studies: Rare variant analysis and high-density imputation

Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 others, Biernacka, J. M., Weinshilboum, R. M., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Uher, R. & Lewis, C. M., May 22 2018, In : Pharmacogenomics Journal. 18, 3, p. 413-421 9 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Antidepressive Agents
Gene Ontology
Exome
Single Nucleotide Polymorphism
6 Citations (Scopus)

PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort

Preuss, U. W., Winham, S. J., Biernacka, J. M., Geske, J. R., Bakalkin, G., Koller, G., Zill, P., Soyka, M. & Karpyak, V. M., Nov 6 2013, In : PLoS One. 8, 11, e78688.

Research output: Contribution to journalArticle

craving
drinking
Drinking
Alcohols
Association reactions
2 Citations (Scopus)

Perils and pitfalls of permutation tests for distinguishing the effects of neighbouring polymorphisms

Biernacka, J. M. & Cordell, H. J., Nov 2006, In : Genetic Epidemiology. 30, 7, p. 582-589 8 p.

Research output: Contribution to journalArticle

Viverridae
Logistic Models
Linkage Disequilibrium
Haplotypes
Alleles
5 Citations (Scopus)

Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine-Learning Approach With Multi-trial Replication

Athreya, A. P., Neavin, D., Carrillo-Roa, T., Skime, M., Biernacka, J., Frye, M. A., Rush, A. J., Wang, L., Binder, E. B., Iyer, R. K., Weinshilboum, R. M. & Bobo, W. V., Jan 1 2019, In : Clinical pharmacology and therapeutics.

Research output: Contribution to journalArticle

Pharmacogenetics
Serotonin Uptake Inhibitors
Antidepressive Agents
Major Depressive Disorder
Citalopram
20 Citations (Scopus)

Pharmacogenomics of antidepressant induced mania: A review and meta-analysis of the serotonin transporter gene (5HTTLPR) association

Biernacka, J. M., McElroy, S. L., Crow, S., Sharp, A., Benitez, J., Veldic, M. D., Kung, S., Cunningham, J. M., Post, R. M., Mrazek, D. & Frye, M. A., Jan 2012, In : Journal of Affective Disorders. 136, 1-2

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Pharmacogenetics
Bipolar Disorder
Antidepressive Agents
Meta-Analysis
13 Citations (Scopus)

Pharmacogenomics of estrogens on changes in carotid artery intima-medial thickness and coronary arterial calcification: Kronos Early Estrogen Prevention Study

Miller, V. M., Jenkins, G. D., Biernacka, J. M., Heit, J. A., Huggins, G. S., Hodis, H. N., Budoff, M. J., Lobo, R. A., Taylor, H. S., Manson, J. E., Black, D. M., Naftolin, F., Mitchell Harman, S. & De Andrade, M., Jan 1 2016, In : Physiological Genomics. 48, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Carotid Arteries
Estrogens
Innate Immunity
Hormones