• 1107 Citations
  • 20 Scopus h-Index
20002020

Research output per year

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Research Output

  • 1107 Citations
  • 20 Scopus h-Index
  • 29 Article
  • 3 Review article
  • 2 Comment/debate
  • 1 Chapter
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Article
2020

Functional Analysis of Hydrolethalus Syndrome Protein HYLS1 in Ciliogenesis and Spermatogenesis in Drosophila

Hou, Y., Wu, Z., Zhang, Y., Chen, H., Hu, J., Guo, Y., Peng, Y. & Wei, Q., May 21 2020, In : Frontiers in Cell and Developmental Biology. 8, 301.

Research output: Contribution to journalArticle

Open Access

Regulation of polycystin expression, maturation and trafficking

Hu, J. & Harris, P. C., Aug 2020, In : Cellular Signalling. 72, 109630.

Research output: Contribution to journalArticle

TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating

Yan, H., Chen, C., Chen, H., Hong, H., Huang, Y., Ling, K., Hu, J. & Wei, Q., Dec 1 2020, In : Nature communications. 11, 1, 2196.

Research output: Contribution to journalArticle

Open Access
2019

Establishment of TUSMi008-A, an induced pluripotent stem cell (iPSC) line from a 76-year old Alzheimer's disease (AD) patient with PAXIP1 gene mutation

Wang, Y., Zhang, J., Hu, J., Li, G., Lei, Y. & Zhao, J., Apr 2019, In : Stem Cell Research. 36, 101391.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules

He, K., Ma, X., Xu, T., Li, Y., Hodge, A., Zhang, Q., Torline, J., Huang, Y., Zhao, J., Ling, K. & Hu, J., Dec 1 2018, In : Nature communications. 9, 1, 3310.

Research output: Contribution to journalArticle

9 Scopus citations
2017

EGFR-induced phosphorylation of type Iγ phosphatidylinositol phosphate kinase promotes pancreatic cancer progression

Chen, C., Wang, X., Fang, J., Xue, J., Xiong, X., Huang, Y., Hu, J. & Ling, K., Jan 1 2017, In : Oncotarget. 8, 26, p. 42621-42637 17 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

GTP-binding of ARL-3 is activated by ARL-13 as a GEF and stabilized by UNC-119

Zhang, Q., Li, Y., Zhang, Y., Torres, V., Harris, P. C., Ling, K. & Hu, J., Apr 22 2016, In : Scientific Reports. 6, 24534.

Research output: Contribution to journalArticle

14 Scopus citations

Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis

Xu, Q., Zhang, Y., Wei, Q., Huang, Y., Hu, J. & Ling, K., Feb 26 2016, In : Nature Communications. 7, 10777.

Research output: Contribution to journalArticle

32 Scopus citations

The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gate

Wei, Q., Zhang, Y., Schouteden, C., Zhang, Y., Zhang, Q., Dong, J., Wonesch, V., Ling, K., Dammermann, A. & Hu, J., Aug 18 2016, In : Nature Communications. 7, 12437.

Research output: Contribution to journalArticle

12 Scopus citations
2015

BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors

Xu, Q., Zhang, Y., Wei, Q., Huang, Y., Li, Y., Ling, K. & Hu, J., Jul 7 2015, In : Scientific Reports. 5, 11855.

Research output: Contribution to journalArticle

31 Scopus citations

The essential roles of transition fibers in the context of cilia

Wei, Q., Ling, K. & Hu, J., Aug 1 2015, In : Current Opinion in Cell Biology. 35, p. 98-105 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
2014

PIPKIγ targets to the centrosome and restrains centriole duplication

Xu, Q., Zhang, Y., Xiong, X., Huang, Y., Salisbury, J. L., Hu, J. & Ling, K., Mar 1 2014, In : Journal of cell science. 127, 6, p. 1293-1305 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Targeting type Iγ phosphatidylinositol phosphate kinase inhibits breast cancer metastasis

Chen, C., Wang, X., Xiong, X., Liu, Q., Huang, Y., Xu, Q., Hu, J., Ge, G. & Ling, K., Dec 8 2014, In : Oncogene. 34, 35, p. 4635-4646 12 p.

Research output: Contribution to journalArticle

18 Scopus citations
2013

Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes

Wei, Q., Xu, Q., Zhang, Y., Li, Y., Zhang, Q., Hu, Z., Harris, P. C., Torres, V. E., Ling, K. & Hu, J., Nov 15 2013, In : Nature communications. 4, 3750.

Research output: Contribution to journalArticle

51 Scopus citations
2012

An association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization

Xiong, X., Xu, Q., Huang, Y., Singh, R. D., Anderson, R., Leof, E., Hu, J. & Ling, K., Jan 1 2012, In : Molecular biology of the cell. 23, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors

Li, Y., Zhang, Q., Wei, Q., Zhang, Y., Ling, K. & Hu, J., Nov 1 2012, In : Journal of Cell Biology. 199, 4, p. 589-598 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

The BBSome controls IFT assembly and turnaround in cilia

Wei, Q., Zhang, Y., Li, Y., Zhang, Q., Ling, K. & Hu, J., Sep 1 2012, In : Nature Cell Biology. 14, 9, p. 950-957 8 p.

Research output: Contribution to journalArticle

123 Scopus citations
2010

Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy

Otto, E. A., Hurd, T. W., Airik, R., Chaki, M., Zhou, W., Stoetzel, C., Patil, S. B., Levy, S., Ghosh, A. K., Murga-Zamalloa, C. A., Van Reeuwijk, J., Letteboer, S. J. F., Sang, L., Giles, R. H., Liu, Q., Coene, K. L. M., Estrada-Cuzcano, A., Collin, R. W. J., McLaughlin, H. M., Held, S. & 35 others, Kasanuki, J. M., Ramaswami, G., Conte, J., Lopez, I., Washburn, J., MacDonald, J., Hu, J., Yamashita, Y., Maher, E. R., Guay-Woodford, L. M., Neumann, H. P. H., Obermüller, N., Koenekoop, R. K., Bergmann, C., Bei, X., Lewis, R. A., Katsanis, N., Lopes, V., Williams, D. S., Lyons, R. H., Dang, C. V., Brito, D. A., Dias, M. B., Zhang, X., Cavalcoli, J. D., Nürnberg, G., Nürnberg, P., Pierce, E. A., Jackson, P. K., Antignac, C., Saunier, S., Roepman, R., Dollfus, H., Khanna, H. & Hildebrandt, F., Oct 1 2010, In : Nature Genetics. 42, 10, p. 840-850 11 p.

Research output: Contribution to journalArticle

212 Scopus citations

The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis

Li, Y., Wei, Q., Zhang, Y., Ling, K. & Hu, J., Jun 14 2010, In : Journal of Cell Biology. 189, 6, p. 1039-1051 13 p.

Research output: Contribution to journalArticle

95 Scopus citations
2007

STAM and Hrs down-regulate ciliary TRP receptors

Hu, J., Wittekind, S. G. & Barr, M. M., Sep 1 2007, In : Molecular biology of the cell. 18, 9, p. 3277-3289 13 p.

Research output: Contribution to journalArticle

43 Scopus citations
2006

Casein kinase II and calcineurin modulate TRPP function and ciliary localization

Hu, J., Bae, Y. K., Knobel, K. M. & Barr, M. M., May 1 2006, In : Molecular biology of the cell. 17, 5, p. 2200-2211 12 p.

Research output: Contribution to journalArticle

49 Scopus citations

General and cell-type specific mechanisms target TRPP2/PKD-2 to cilia

Bae, Y. K., Qin, H., Knobel, K. M., Hu, J., Rosenbaum, J. L. & Barr, M. M., Oct 1 2006, In : Development. 133, 19, p. 3859-3870 12 p.

Research output: Contribution to journalArticle

73 Scopus citations
2005

ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling

Hu, J. & Barr, M. M., Feb 1 2005, In : Molecular biology of the cell. 16, 2, p. 458-469 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Identification and characterization of a novel splice variant of β3 subunit of GABA A receptor in rat testis and spermatozoa

Li, S. F., Hu, J. H., Yan, Y. C., Chen, Y. G., Koide, S. S. & Li, Y. P., Feb 1 2005, In : International Journal of Biochemistry and Cell Biology. 37, 2, p. 350-360 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2002

Biphasic effect of GABA on rat sperm acrosome reaction: Involvement of GABAa and GABAb receptors

Hu, J. H., He, X. B., Wu, Q., Yan, Y. C. & Koide, S. S., Aug 19 2002, In : Archives of Andrology. 48, 5, p. 369-378 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Identification of γ1 subunit of GABAA receptor in rat testis

Hu, J. H. & Yan, Y. C., Mar 2002, In : Cell Research. 12, 1, p. 33-37 5 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Subunit composition and function of GABAA receptors of rat spermatozoa

Hu, J. H., He, X. B., Wu, Q., Yan, Y. C. & Koide, S. S., Apr 15 2002, In : Neurochemical Research. 27, 3, p. 195-199 5 p.

Research output: Contribution to journalArticle

23 Scopus citations
2001

Identification of GABAB receptor in rat testis and sperm

He, X. B., Hu, J. H., Wu, Q., Yan, Y. C. & Koide, S. S., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 283, 1, p. 243-247 5 p.

Research output: Contribution to journalArticle

34 Scopus citations
2000

Identification of γ-aminobutyric acid transporter (GAT1) on the rat sperm

Hu, J. H., He, X. B. & Yan, Y. C., Mar 2000, In : Cell Research. 10, 1, p. 51-58 8 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations