• 1092 Citations
  • 12 Scopus h-Index
20052019
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Research Output 2005 2019

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Article
2019
1 Citation (Scopus)

Skeletal Muscle Progenitor Cell Heterogeneity

Cho, D. S. & Doles, J., Jan 1 2019, In : Advances in experimental medicine and biology. 1169, p. 179-193 15 p.

Research output: Contribution to journalArticle

Muscle Cells
Muscle
Skeletal Muscle
Stem Cells
Stem cells
2018
33 Citations (Scopus)

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

Tarragó, M. G., Chini, C. C. S., Kanamori, K. S., Warner, G. M., Caride, A., de Oliveira, G. C., Rud, M., Samani, A., Hein, K. Z., Huang, R., Jurk, D., Cho, D. S., Boslett, J. J., Miller, J. D., Zweier, J. L., Passos, J., Doles, J., Becherer, D. J. & Chini, E. N., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

NAD
NAD+ Nucleosidase
Telomere
DNA Damage
Sirtuins
1 Citation (Scopus)
Weight Loss
Weight Gain
Neoplasms
Weights and Measures
Tomography
3 Citations (Scopus)

Metabolomic analyses reveal extensive progenitor cell deficiencies in a mouse model of Duchenne muscular dystrophy

Joseph, J., Cho, D. S. & Doles, J., Dec 1 2018, In : Metabolites. 8, 4, 61.

Research output: Contribution to journalArticle

Metabolomics
Duchenne Muscular Dystrophy
Stem Cells
Muscle
Dystrophin
2017
10 Citations (Scopus)

Single cell transcriptome analysis of muscle satellite cells reveals widespread transcriptional heterogeneity

Cho, D. S. & Doles, J., Dec 15 2017, In : Gene. 636, p. 54-63 10 p.

Research output: Contribution to journalArticle

Single-Cell Analysis
Gene Expression Profiling
Muscle Cells
RNA Sequence Analysis
Skeletal Muscle
4 Citations (Scopus)

Tumor-derived cytokines impair myogenesis and alter the skeletal muscle immune microenvironment

Hogan, K. A., Cho, D. S., Arneson, P. C., Samani, A., Palines, P., Yang, Y. D. & Doles, J., Jan 1 2017, (Accepted/In press) In : Cytokine.

Research output: Contribution to journalArticle

Muscle Development
Muscle
Tumors
Skeletal Muscle
Cytokines
2015
48 Citations (Scopus)

Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay

Hausburg, M. A., Doles, J., Clement, S. L., Cadwallader, A. B., Hall, M. N., Blackshear, P. J., Lykke-Andersen, J. & Olwin, B. B., Mar 27 2015, In : eLife. 2015, 4

Research output: Contribution to journalArticle

Tristetraprolin
RNA Stability
Satellites
Messenger RNA
Muscle
2014
233 Citations (Scopus)

P38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

Bernet, J. D., Doles, J., Hall, J. K., Kelly Tanaka, K., Carter, T. A. & Olwin, B. B., Jan 1 2014, In : Nature Medicine. 20, 3, p. 265-271 7 p.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Stem cells
Muscle
Sarcopenia
Skeletal Muscle
2012
72 Citations (Scopus)

Age-associated inflammation inhibits epidermal stem cell function

Doles, J., Storer, M., Cozzuto, L., Roma, G. & Keyes, W. M., Oct 1 2012, In : Genes and Development. 26, 19, p. 2144-2153 10 p.

Research output: Contribution to journalArticle

Stem Cells
Inflammation
Homeostasis
Cytokines
Skin Aging
2010
119 Citations (Scopus)

Error-prone translesion synthesis mediates acquired chemoresistance

Xie, K., Doles, J., Hemann, M. T. & Walkera, G. C., Nov 30 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 48, p. 20792-20797 6 p.

Research output: Contribution to journalArticle

Neoplasms
DNA
Drug Resistance
Drug Therapy
Mutation
20 Citations (Scopus)

Nek4 status differentially alters sensitivity to distinct microtubule poisons

Doles, J. & Hemann, M. T., Feb 1 2010, In : Cancer Research. 70, 3, p. 1033-1041 9 p.

Research output: Contribution to journalArticle

Poisons
Microtubules
Paclitaxel
Vincristine
Non-Small Cell Lung Carcinoma
108 Citations (Scopus)

Suppression of Rev3, the catalytic subunit of Pol?, sensitizes drug-resistant lung tumors to chemotherapy

Doles, J., Oliver, T. G., Cameron, E. R., Hsu, G., Jacks, T., Walker, G. C. & Hemann, M. T., Nov 30 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 48, p. 20786-20791 6 p.

Research output: Contribution to journalArticle

Catalytic Domain
Cisplatin
Drug Therapy
Lung
Pharmaceutical Preparations
2008
201 Citations (Scopus)

Topoisomerase levels determine chemotherapy response in vitro and in vivo

Burgess, D. J., Doles, J., Zender, L., Xue, W., Ma, B., McCombie, W. R., Hannon, G. J., Lowe, S. W. & Hemann, M. T., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9053-9058 6 p.

Research output: Contribution to journalArticle

Poisons
Drug Therapy
Doxorubicin
RNA Interference
Lymphoma
2006
61 Citations (Scopus)

Functional compensation in Hedgehog signaling during mouse prostate development

Doles, J., Cook, C., Shi, X., Valosky, J., Lipinski, R. & Bushman, W., Jul 1 2006, In : Developmental Biology. 295, 1, p. 13-25 13 p.

Research output: Contribution to journalArticle

Hedgehogs
Prostate
Focal Epithelial Hyperplasia
Morphogenesis
Transgenic Mice
69 Citations (Scopus)

Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling

Lipinski, R. J., Gipp, J. J., Zhang, J., Doles, J. & Bushman, W., Jul 1 2006, In : Experimental Cell Research. 312, 11, p. 1925-1938 14 p.

Research output: Contribution to journalArticle

Hedgehogs
Transcription Factors
Gene Expression
Genes
Transcription Factor 3
2005
28 Citations (Scopus)

Growth, morphogenesis, and differentiation during mouse prostate development in situ, in renal grafts, and in vitro

Doles, J., Vezina, C. M., Lipinski, R. J., Peterson, R. E. & Bushman, W., Dec 1 2005, In : Prostate. 65, 4, p. 390-399 10 p.

Research output: Contribution to journalArticle

Organ Culture Techniques
Morphogenesis
Prostate
Transplants
Kidney
53 Citations (Scopus)

The impact of carrier flow rate and infusion set dead-volume on the dynamics of intravenous drug delivery

Lovich, M. A., Doles, J. & Peterfreund, R. A., Apr 1 2005, In : Anesthesia and Analgesia. 100, 4, p. 1048-1055 8 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Drug Carriers
Infusion Pumps
Methylene Blue
Reaction Time