• 12930 Citations
  • 50 Scopus h-Index
1980 …2021
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Research Output 1993 2019

  • 12930 Citations
  • 50 Scopus h-Index
  • 186 Article
  • 4 Review article
  • 1 Comment/debate
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Article
2013
76 Citations (Scopus)

Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: Results of a prospective pilot study

Pafundi, D. H., Laack, N. N., Youland, R. S., Parney, I. F., Lowe, V., Giannini, C., Kemp, B. J., Grams, M. P., Morris, J. M., Hoover, J. M., Hu, L. S., Sarkaria, J. N. & Brinkmann, D. H., Aug 2013, In : Neuro-Oncology. 15, 8, p. 1058-1067 10 p.

Research output: Contribution to journalArticle

Glioma
Radiotherapy
Prospective Studies
Biopsy
Astrocytoma
186 Citations (Scopus)

Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake

Flavahan, W. A., Wu, Q., Hitomi, M., Rahim, N., Kim, Y., Sloan, A. E., Weil, R. J., Nakano, I., Sarkaria, J. N., Stringer, B. W., Day, B. W., Li, M., Lathia, J. D., Rich, J. N. & Hjelmeland, A. B., Oct 2013, In : Nature Neuroscience. 16, 10, p. 1373-1382 10 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Brain Neoplasms
Glucose
Glucose Transporter Type 3
Neoplasms
24 Citations (Scopus)

Brain tumor stem cell multipotency correlates with nanog expression and extent of passaging in human glioblastoma xenografts

Higgins, D. M., Wang, R., Milligan, B., Schroeder, M., Carlson, B., Pokorny, J., Cheshier, S. H., Meyer, F. B., Weissman, I. L., Sarkaria, J. N. & Henley, J. R., May 2013, In : Oncotarget. 4, 5, p. 792-801 10 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Glioblastoma
Heterografts
Brain Neoplasms
Survival
11 Citations (Scopus)

Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models

Cen, L., Carlson, B. L., Pokorny, J. L., Mladek, A. C., Grogan, P. T., Schroeder, M. A., Decker, P. A., Anderson, S. K., Giannini, C., Wu, W., Ballman, K. V., Kitange, G. J. & Sarkaria, J. N., Jun 2013, In : Neuro-Oncology. 15, 6, p. 735-746 12 p.

Research output: Contribution to journalArticle

temozolomide
Methyltransferases
Glioblastoma
Heterografts
Placebos
52 Citations (Scopus)

Impairment of glioma stem cell survival and growth by a novel inhibitor for survivin-ran protein complex

Guvenc, H., Pavlyukov, M. S., Joshi, K., Kurt, H., Banasavadi-Siddegowda, Y. K., Mao, P., Hong, C., Yamada, R., Kwon, C. H., Bhasin, D., Chettiar, S., Kitange, G., Park, I. H., Sarkaria, J. N., Li, C., Shakhparonov, M. I. & Nakano, I., Feb 1 2013, In : Clinical Cancer Research. 19, 3, p. 631-642 12 p.

Research output: Contribution to journalArticle

ran GTP-Binding Protein
Glioblastoma
Glioma
Cell Survival
Stem Cells
55 Citations (Scopus)

Increased bowel toxicity in patients treated with a vascular endothelial growth factor inhibitor (VEGFI) after stereotactic body radiation therapy (SBRT)

Barney, B. M., Markovic, S. N., Laack, N. N., Miller, R. C., Sarkaria, J. N., Macdonald, O. K., Bauer, H. J. & Olivier, K. R., Sep 1 2013, In : International Journal of Radiation Oncology Biology Physics. 87, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

toxicity
inhibitors
Vascular Endothelial Growth Factor A
radiation therapy
Radiotherapy
32 Citations (Scopus)

Oncolytic measles virus strains have significant antitumor activity against glioma stem cells

Allen, C., Opyrchal, M., Aderca, I., Schroeder, M. A., Sarkaria, J. N., Domingo, E., Federspiel, M. J. & Galanis, E., Apr 2013, In : Gene Therapy. 20, 4, p. 444-449 6 p.

Research output: Contribution to journalArticle

Oncolytic Viruses
Measles virus
Glioma
Stem Cells
Glioblastoma
32 Citations (Scopus)

Opportunities and challenges in the era of molecularly targeted agents and radiation therapy

Lin, S. H., George, T. J., Ben-Josef, E., Bradley, J., Choe, K. S., Edelman, M. J., Guha, C., Krishnan, S., Lawrence, T. S., Le, Q. T., Lu, B., Mehta, M., Peereboom, D., Sarkaria, J. N., Seong, J., Wang, D., Welliver, M. X., Coleman, C. N., Vikram, B., Yoo, S. & 1 others, Chung, C. H., May 15 2013, In : Journal of the National Cancer Institute. 105, 10, p. 686-693 8 p.

Research output: Contribution to journalArticle

Radiotherapy
Neoplasms
Education
Radiation Oncology
National Cancer Institute (U.S.)
16 Citations (Scopus)

P53 isoform profiling in glioblastoma and injured brain

Takahashi, R., Giannini, C., Sarkaria, J. N., Schroeder, M., Rogers, J., Mastroeni, D. & Scrable, H., Jun 27 2013, In : Oncogene. 32, 26, p. 3165-3174 10 p.

Research output: Contribution to journalArticle

Glioblastoma
Protein Isoforms
Brain
Neoplasms
Gliosis
63 Citations (Scopus)

Posttranscriptional regulation of per1 underlies the oncogenic function of IREα

Pluquet, O., Dejeans, N., Bouchecareilh, M., Lhomond, S., Pineau, R., Higa, A., Delugin, M., Combe, C., Loriot, S., Cubel, G., Dugot-Senant, N., Vital, A., Loiseau, H., Gosline, S. J. C., Taouji, S., Hallett, M., Sarkaria, J. N., Anderson, K., Wu, W., Rodriguez, F. J. & 4 others, Rosenbaum, J., Saltel, F., Fernandez-Zapico, M. E. & Chevet, E., Aug 1 2013, In : Cancer Research. 73, 15, p. 4732-4743 12 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Endoribonucleases
Circadian Clocks
Messenger RNA
Carcinogenesis
45 Citations (Scopus)

Targeting Src Family Kinases Inhibits Bevacizumab-Induced Glioma Cell Invasion

Huveldt, D., Lewis-Tuffin, L. J., Carlson, B. L., Schroeder, M. A., Rodriguez, F., Giannini, C., Galanis, E., Sarkaria, J. N. & Anastasiadis, P. Z., Feb 14 2013, In : PLoS One. 8, 2, e56505.

Research output: Contribution to journalArticle

cell invasion
src-Family Kinases
Glioma
phosphotransferases (kinases)
Glioblastoma
293 Citations (Scopus)

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

Chan, K. M., Fang, D., Gan, H., Hashizume, R., Yu, C., Schroeder, M., Gupta, N., Mueller, S., David James, C., Jenkins, R. B., Sarkaria, J. N. & Zhang, Z., May 1 2013, In : Genes and Development. 27, 9, p. 985-990 6 p.

Research output: Contribution to journalArticle

Glioma
Histones
Methylation
Pediatrics
Gene Expression
51 Citations (Scopus)

The role of LAT1 in 18F-DOPA uptake in malignant gliomas

Youland, R. S., Kitange, G. J., Peterson, T. E., Pafundi, D. H., Ramiscal, J. A., Pokorny, J. L., Giannini, C., Laack, N. N., Parney, I. F., Lowe, V., Brinkmann, D. H. & Sarkaria, J. N., Jan 2013, In : Journal of Neuro-Oncology. 111, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
Phenylalanine
Glioma
Small Interfering RNA
Glioblastoma
2012
40 Citations (Scopus)

Active efflux of dasatinib from the brain limits efficacy against murine glioblastoma: Broad implications for the clinical use of molecularly targeted agents

Agarwal, S., Mittapalli, R. K., Zellmer, D. M., Gallardo, J. L., Donelson, R., Seiler, C., Decker, S. A., SantaCruz, K. S., Pokorny, J. L., Sarkaria, J. N., Elmquist, W. F. & Ohlfest, J. R., Oct 2012, In : Molecular Cancer Therapeutics. 11, 10, p. 2183-2192 10 p.

Research output: Contribution to journalArticle

Glioblastoma
P-Glycoprotein
Breast Neoplasms
Brain
Glioma
74 Citations (Scopus)

Alkylpurine - DNA - N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients

Agnihotri, S., Gajadhar, A. S., Ternamian, C., Gorlia, T., Diefes, K. L., Mischel, P. S., Kelly, J., McGown, G., Thorncroft, M., Carlson, B. L., Sarkaria, J. N., Margison, G. P., Aldape, K., Hawkins, C., Hegi, M. & Guha, A., Jan 3 2012, In : Journal of Clinical Investigation. 122, 1, p. 253-266 14 p.

Research output: Contribution to journalArticle

temozolomide
DNA Glycosylases
Glioblastoma
Heterografts
Survival

Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients (Journal of Clinical Investigation (2012) 122, 1, (253-266) DOI: 10.1172/JCI59334)

Agnihotri, S., Gajadhar, A. S., Ternamian, C., Gorlia, T., Diefes, K. L., Mischel, P. S., Kelly, J., McGown, G., Thorncroft, M., Carlson, B. L., Sarkaria, J. N., Margison, G. P., Aldape, K., Hawkins, C., Hegi, M. & Guha, A., Feb 2012, In : Journal of Clinical Investigation. 122, 2, p. 782 1 p.

Research output: Contribution to journalArticle

temozolomide
DNA Glycosylases
Glioblastoma
Heterografts
Survival
32 Citations (Scopus)

ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells

Nadkarni, A., Shrivastav, M., Mladek, A. C., Schwingler, P. M., Grogan, P. T., Chen, J. & Sarkaria, J. N., Dec 2012, In : Journal of Neuro-Oncology. 110, 3, p. 349-357 9 p.

Research output: Contribution to journalArticle

temozolomide
Ataxia Telangiectasia
Glioblastoma
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one
70 Citations (Scopus)

Inhibition of histone deacetylation potentiates the evolution of acquired temozolomide resistance linked to MGMT upregulation in glioblastoma xenografts

Kitange, G. J., Mladek, A. C., Carlson, B. L., Schroeder, M. A., Pokorny, J. L., Cen, L., Decker, P. A., Wu, W., Lomberk, G. A., Gupta, S. K., Urrutia, R. A. & Sarkaria, J. N., Aug 1 2012, In : Clinical Cancer Research. 18, 15, p. 4070-4079 10 p.

Research output: Contribution to journalArticle

temozolomide
Methyltransferases
Glioblastoma
Heterografts
Histones
55 Citations (Scopus)

Molecular characterization of EGFR and EGFRvIII signaling networks in human glioblastoma tumor xenografts

Johnson, H., Del Rosario, A. M., Bryson, B. D., Schroeder, M. A., Sarkaria, J. N. & White, F. M., Dec 2012, In : Molecular and Cellular Proteomics. 11, 12, p. 1724-1740 17 p.

Research output: Contribution to journalArticle

Glioblastoma
Epidermal Growth Factor Receptor
Heterografts
Protein-Tyrosine Kinases
Tumors
83 Citations (Scopus)

P16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells

Cen, L., Carlson, B. L., Schroeder, M. A., Ostrem, J. L., Kitange, G. J., Mladek, A. C., Fink, S. R., Decker, P. A., Wu, W., Kim, J. S., Waldman, T., Jenkins, R. B. & Sarkaria, J. N., Jul 2012, In : Neuro-Oncology. 14, 7, p. 870-881 12 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Glioblastoma
Heterografts
Cell Proliferation
Survival
15 Citations (Scopus)

Phase i study of temsirolimus in combination with EKB-569 in patients with advanced solid tumors

Bryce, A. H., Rao, R., Sarkaria, J. N., Reid, J. M., Qi, Y., Qin, R., James, C. D., Jenkins, R. B., Boni, J., Erlichman, C. & Haluska, P., Oct 2012, In : Investigational New Drugs. 30, 5, p. 1934-1941 8 p.

Research output: Contribution to journalArticle

Maximum Tolerated Dose
Pharmacokinetics
Nausea
Diarrhea
Neoplasms
47 Citations (Scopus)

Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis

Feng, H., Hu, B., Jarzynka, M. J., Li, Y., Keezer, S., Johns, T. G., Tang, C. K., Hamilton, R. L., Vuori, K., Nishikawa, R., Sarkaria, J. N., Fenton, T., Cheng, T., Furnari, F. B., Cavenee, W. K. & Cheng, S. Y., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 3018-3023 6 p.

Research output: Contribution to journalArticle

Cytokinesis
src-Family Kinases
Glioblastoma
Tyrosine
Carcinogenesis
44 Citations (Scopus)

Targeting the PI3K pathway in the brain - Efficacy of a PI3K inhibitor optimized to cross the blood-brain barrier

Salphati, L., Heffron, T. P., Alicke, B., Nishimura, M., Barck, K., Carano, R. A., Cheong, J., Edgar, K. A., Greve, J., Kharbanda, S., Koeppen, H., Lau, S., Lee, L. B., Pang, J., Plise, E. G., Pokorny, J. L., Reslan, H. B., Sarkaria, J. N., Wallin, J. J., Zhang, X. & 3 others, Gould, S. E., Olivero, A. G. & Phillips, H. S., Nov 15 2012, In : Clinical Cancer Research. 18, 22, p. 6239-6248 10 p.

Research output: Contribution to journalArticle

Blood-Brain Barrier
Phosphatidylinositol 3-Kinases
Glioblastoma
Brain
P-Glycoprotein
2011
72 Citations (Scopus)

Activation of Rac1 by Src-dependent phosphorylation of Dock180 Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans

Feng, H., Hu, B., Liu, K. W., Li, Y., Lu, X., Cheng, T., Yiin, J. J., Lu, S., Keezer, S., Fenton, T., Furnari, F. B., Hamilton, R. L., Vuori, K., Sarkaria, J. N., Nagane, M., Nishikawa, R., Cavenee, W. K. & Cheng, S. Y., Dec 1 2011, In : Journal of Clinical Investigation. 121, 12, p. 4670-4684 15 p.

Research output: Contribution to journalArticle

Glioma
Tyrosine
Carcinogenesis
Phosphorylation
Glioblastoma
66 Citations (Scopus)

A phase 2 study of temsirolimus (CCI-779) in patients with soft tissue sarcomas: A study of the mayo phase 2 Consortium (P2C)

Okuno, S. H., Bailey, H., Mahoney, M. R., Adkins, D., Maples, W., Fitch, T., Ettinger, D., Erlichman, C. & Sarkaria, J. N., Aug 1 2011, In : Cancer. 117, 15, p. 3468-3475 8 p.

Research output: Contribution to journalArticle

Sarcoma
Confidence Intervals
Adjuvant Chemotherapy
Leiomyosarcoma
Premedication
25 Citations (Scopus)

Effective radiovirotherapy for malignant gliomas by using oncolytic measles virus strains encoding the sodium iodide symporter (MV-NIS)

Opyrchal, M., Allen, C., Iankov, I., Aderca, I., Schroeder, M., Sarkaria, J. N. & Galanis, E., Dec 20 2011, In : Human Gene Therapy. 23, 4, p. 419-427 9 p.

Research output: Contribution to journalArticle

Oncolytic Viruses
Measles virus
Glioma
Glioblastoma
Carcinoembryonic Antigen
71 Citations (Scopus)
Drug Discovery
Glioblastoma
Heterografts
Maintenance
Neoplasms
107 Citations (Scopus)

Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines

Peasland, A., Wang, L. Z., Rowling, E., Kyle, S., Chen, T., Hopkins, A., Cliby, W. A., Sarkaria, J. N., Beale, G., Edmondson, R. J. & Curtin, N. J., Jul 26 2011, In : British Journal of Cancer. 105, 3, p. 372-381 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Breast Neoplasms
Cell Line
DNA Mismatch Repair
Cisplatin
16 Citations (Scopus)

Incorporation of biomarker assessment in novel clinical trial designs: Personalizing brain tumor treatments

Galanis, E., Wu, W., Sarkaria, J. N., Chang, S. M., Colman, H., Sargent, D. & Reardon, D. A., Feb 2011, In : Current Oncology Reports. 13, 1, p. 42-49 8 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Biomarkers
Clinical Trials
Molecular Biology
Therapeutics
268 Citations (Scopus)
Homologous Recombination
DNA-Activated Protein Kinase
Poly(ADP-ribose) Polymerases
Genomic Instability
Poisons
55 Citations (Scopus)
temozolomide
Glioblastoma
radiation therapy
Radiotherapy
cancer
19 Citations (Scopus)

Phenotypic variations in NF1-associated low grade astrocytomas: Possible role for increased mTOR activation in a subset

Jentoft, M., Giannini, C., Cen, L., Scheithauer, B. W., Hoesley, B., Sarkaria, J. N., Abell-Aleff, P. C., Rodriguez, E. F., Li, Y. & Rodriguez, F. J., 2011, In : International Journal of Clinical and Experimental Pathology. 4, 1, p. 43-57 15 p.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Astrocytoma
S 6
Electron Microscopy
Western Blotting

Phenotypic variations in NF1-associated low grade astrocytomas: Possible role for increased mTOR activation in a subset

Jentoft, M., Giannini, C., Cen, L., Scheithauer, B. W., Hoesley, B., Sarkaria, J. N., Abell-Aleff, P. C., Rodriguez, E. F., Li, Y. & Rodriguez, F. J., 2011, In : International Journal of Clinical and Experimental Pathology. 4, 1, p. 13-21 9 p.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Astrocytoma
S 6
Electron Microscopy
Western Blotting
84 Citations (Scopus)

PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma

Rodriguez, E. F., Scheithauer, B. W., Giannini, C., Rynearson, A., Cen, L., Hoesley, B., Gilmer-Flynn, H., Sarkaria, J. N., Jenkins, S., Long, J. & Rodriguez, F. J., Mar 2011, In : Acta Neuropathologica. 121, 3, p. 407-420 14 p.

Research output: Contribution to journalArticle

Astrocytoma
Phosphatidylinositol 3-Kinases
Molecular Biology
Immunohistochemistry
1 Citation (Scopus)

WE‐G‐214‐02: Utility of 18F‐FDOPA PET for Radiotherapy Target Delineation in Glioma Patients

Pafundi, D., Brinkmann, D. H., Laack, N. N., Sarkaria, J. N., Yan, E., Kemp, B. & Lowe, V., 2011, In : Medical Physics. 38, 6, p. 3830 1 p.

Research output: Contribution to journalArticle

Gadolinium
Glioma
Radiotherapy
Observer Variation
Pathology
143 Citations (Scopus)

WWP2 is an E3 ubiquitin ligase for PTEN

Maddika, S., Kavela, S., Rani, N., Palicharla, V. R., Pokorny, J. L., Sarkaria, J. N. & Chen, J., Jun 2011, In : Nature Cell Biology. 13, 6, p. 728-733 6 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Ubiquitination
Neoplasms
PTEN Phosphohydrolase
Embryonic Stem Cells
2010
82 Citations (Scopus)

Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain

Oliva, C. R., Nozell, S. E., Diers, A., McClugage, S. G., Sarkaria, J. N., Markert, J. M., Darley-Usmar, V. M., Bailey, S. M., Gillespie, G. Y., Landar, A. & Griguer, C. E., Dec 17 2010, In : Journal of Biological Chemistry. 285, 51, p. 39759-39767 9 p.

Research output: Contribution to journalArticle

temozolomide
Electron Transport
Glioma
Mitochondria
Glioblastoma
43 Citations (Scopus)

An orally bioavailable c-Met kinase inhibitor potently inhibits brain tumor malignancy and growth

Guessous, F., Zhang, F., DiPierro, C., Marcinkiewicz, L., Sarkaria, J. N., Schiff, D., Buchanan, S. & Abounader, R., Jan 2010, In : Anti-Cancer Agents in Medicinal Chemistry. 10, 1, p. 28-35 8 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Phosphotransferases
Growth
Glioma
Hepatocyte Growth Factor
53 Citations (Scopus)
temozolomide
Glioblastoma
Radiation
Antibiotic Prophylaxis
Chemoradiotherapy
28 Citations (Scopus)

Expression of CD74 in high grade gliomas: A potential role in temozolomide resistance

Kitange, G. J., Carlson, B. L., Schroeder, M. A., Decker, P. A., Morlan, B. W., Wu, W., Ballman, K. V., Giannini, C. & Sarkaria, J. N., Nov 2010, In : Journal of Neuro-Oncology. 100, 2, p. 177-186 10 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Glioma
Small Interfering RNA
Methyltransferases
3347 Citations (Scopus)

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Verhaak, R. G. W., Hoadley, K. A., Purdom, E., Wang, V., Qi, Y., Wilkerson, M. D., Miller, C. R., Ding, L., Golub, T., Mesirov, J. P., Alexe, G., Lawrence, M., O'Kelly, M., Tamayo, P., Weir, B. A., Gabriel, S., Winckler, W., Gupta, S., Jakkula, L., Feiler, H. S. & 13 others, Hodgson, J. G., James, C. D., Sarkaria, J. N., Brennan, C., Kahn, A., Spellman, P. T., Wilson, R. K., Speed, T. P., Gray, J. W., Meyerson, M., Getz, G., Perou, C. M. & Hayes, D. N., Jan 19 2010, In : Cancer Cell. 17, 1, p. 98-110 13 p.

Research output: Contribution to journalArticle

Glioblastoma
Gene Expression
Atlases
Genome
Mutation
91 Citations (Scopus)

Misregulated E-Cadherin expression associated with an aggressive brain tumor phenotype

Lewis-Tuffin, L. J., Rodriguez, F., Giannini, C., Scheithauer, B., Necela, B. M., Sarkaria, J. N. & Anastasiadis, P. Z., 2010, In : PLoS One. 5, 10, e13665.

Research output: Contribution to journalArticle

cadherins
Cadherins
Brain Neoplasms
Tumors
Brain
29 Citations (Scopus)

ZD6474, a multitargeted inhibitor for receptor tyrosine kinases, suppresses growth of gliomas expressing an epidermal growth factor receptor mutant, EGFRvIII, in the brain

Yiin, J. J., Hu, B., Schornack, P. A., Sengar, R. S., Liu, K. W., Feng, H., Lieberman, F. S., Chiou, S. H., Sarkaria, J. N., Wiener, E. C., Ma, H. I. & Cheng, S. Y., Apr 2010, In : Molecular Cancer Therapeutics. 9, 4, p. 929-941 13 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor
Glioma
Brain
Growth
2009
8 Citations (Scopus)

Bioluminescent imaging of intracranial vestibular schwannoma xenografts in NOD/SCID mice

Neff, B. A., Voss, S. G., Allen, C., Schroeder, M. A., Driscoll, C. L. W., Link, M. J., Galanis, E. & Sarkaria, J. N., Jan 2009, In : Otology and Neurotology. 30, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Acoustic Neuroma
SCID Mice
Heterografts
Photons
58 Citations (Scopus)

Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma

Lines, X., Clarke, M. J., Mulligan, E. A., Grogan, P. T., Mladek, A. C., Carlson, B. L., Schroeder, M. A., Curtin, N. J., Lou, Z., Decker, P. A., Wu, W., Plummer, E. R. & Sarkaria, J. N., Feb 1 2009, In : Molecular Cancer Therapeutics. 8, 2, p. 407-414 8 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Radiotherapy
Heterografts
Survival
51 Citations (Scopus)

Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model

Kitange, G. J., Carlson, B. L., Mladek, A. C., Decker, P. A., Schroeder, M. A., Wu, W., Grogan, P. T., Giannini, C., Ballman, K. V., Buckner, J. C., David James, C. & Sarkaria, J. N., 2009, In : Journal of Neuro-Oncology. 92, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

temozolomide
Methyltransferases
Glioblastoma
Heterografts
Methylation
117 Citations (Scopus)

Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts

Kitange, G. J., Carlson, B. L., Schroeder, M. A., Grogan, P. T., Lamont, J. D., Decker, P. A., Wu, W., James, C. D. & Sarkaria, J. N., Jun 2009, In : Neuro-Oncology. 11, 3, p. 281-291 11 p.

Research output: Contribution to journalArticle

temozolomide
Methyltransferases
Glioblastoma
Heterografts
DNA
49 Citations (Scopus)

Radiosensitizing Effects of Temozolomide Observed in vivo only in a Subset of O6-Methylguanine-DNA Methyltransferase Methylated Glioblastoma Multiforme Xenografts

Carlson, B. L., Grogan, P. T., Mladek, A. C., Schroeder, M. A., Kitange, G. J., Decker, P. A., Giannini, C., Wu, W., Ballman, K. A., James, C. D. & Sarkaria, J. N., Sep 1 2009, In : International Journal of Radiation Oncology Biology Physics. 75, 1, p. 212-219 8 p.

Research output: Contribution to journalArticle

temozolomide
Radiation-Sensitizing Agents
Methyltransferases
Glioblastoma
Heterografts
2008
38 Citations (Scopus)

Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypes

Rodriguez, F. J., Giannini, C., Asmann, Y., Sharma, M. K., Perry, A., Tibbetts, K. M., Jenkins, R. B., Scheithauer, B. W., Anant, S., Jenkins, S., Eberhart, C. G., Sarkaria, J. N. & Gutmann, D. H., Dec 2008, In : Journal of Neuropathology and Experimental Neurology. 67, 12, p. 1194-1204 11 p.

Research output: Contribution to journalArticle

Astrocytoma
Gene Expression Profiling
Biomarkers
Neurofibromatosis 1
aldehyde dehydrogenase 1
49 Citations (Scopus)

Interleukin-13 displaying retargeted oncolytic measles virus strains have significant activity against gliomas with improved specificity

Allen, C., Paraskevakou, G., Iankov, I., Giannini, C., Schroeder, M., Sarkaria, J. N., Schroeder, M., Puri, R. K., Russell, S. J. & Galanis, E., 2008, In : Molecular Therapy. 16, 9, p. 1556-1564 9 p.

Research output: Contribution to journalArticle

Interleukin-13 Receptors
Oncolytic Viruses
Measles virus
Interleukin-13
Glioma