• 14882 Citations
  • 56 Scopus h-Index
1993 …2020

Research output per year

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Research Output

2018

Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data

Sarkaria, J. N., Hu, L. S., Parney, I. F., Pafundi, D. H., Brinkmann, D. H., Laack, N. N., Giannini, C., Burns, T. C., Kizilbash, S. H., Laramy, J. K., Swanson, K. R., Kaufmann, T. J., Brown, P. D., Agar, N. Y. R., Galanis, E., Buckner, J. C. & Elmquist, W. F., Jan 22 2018, In : Neuro-oncology. 20, 2, p. 184-191 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

LPA signaling is regulated through the primary cilium: A novel target in glioblastoma

Loskutov, Y. V., Griffin, C. L., Marinak, K. M., Bobko, A., Margaryan, N. V., Geldenhuys, W. J., Sarkaria, J. N. & Pugacheva, E. N., Mar 1 2018, In : Oncogene. 37, 11, p. 1457-1471 15 p.

Research output: Contribution to journalArticle

15 Scopus citations

Modeling the diffusion of D-2-hydroxyglutarate from IDH1 mutant gliomas in the central nervous system

Linninger, A., Hartung, G. A., Liu, B. P., Mirkov, S., Tangen, K., Lukas, R. V., Unruh, D., David James, C., Sarkaria, J. N. & Horbinski, C., 2018, In : Neuro-oncology. 20, 9, p. 1197-1206 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Molecular and structural traits of insulin receptor substrate 1/LC3 nuclear structures and their role in autophagy control and tumor cell survival

Lassak, A., Dean, M., Wyczechowsk, D., Wilk, A., Marrero, L., Trillo-Tinoco, J., Hamid Boulares, A., Sarkaria, J. N., Valle, L. D., Peruzzi, F., Ochoa, A. & Reiss, K., May 1 2018, In : Molecular and cellular biology. 38, 10, e00608.

Research output: Contribution to journalArticle

2 Scopus citations

NOTCH3 expression is linked to breast cancer seeding and distant metastasis

Leontovich, A. A., Jalalirad, M., Salisbury, J. L., Mills, L., Haddox, C., Schroeder, M., Tuma, A., Guicciardi, M. E., Zammataro, L., Gambino, M. W., Amato, A., Di Leonardo, A., McCubrey, J., Lange, C. A., Liu, M., Haddad, T., Goetz, M., Boughey, J., Sarkaria, J., Wang, L. & 3 others, Ingle, J. N., Galanis, E. & D'Assoro, A. B., Sep 4 2018, In : Breast Cancer Research. 20, 1, 105.

Research output: Contribution to journalArticle

14 Scopus citations

Pharmacokinetic assessment of cooperative efflux of the multitargeted kinase inhibitor ponatinib across the blood-brain barrier

Laramy, J. K., Kim, M., Parrish, K. E., Sarkaria, J. N. & Elmquist, W. F., May 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 2, p. 249-261 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Phase 1/2 trial of temsirolimus and sorafenib in the treatment of patients with recurrent glioblastoma: North Central Cancer Treatment Group Study/Alliance N0572

Schiff, D., Jaeckle, K. A., Anderson, S. K., Galanis, E., Giannini, C., Buckner, J. C., Stella, P., Flynn, P. J., Erickson, B. J., Schwerkoske, J. F., Kaluza, V., Twohy, E., Dancey, J., Wright, J. & Sarkaria, J. N., Apr 1 2018, In : Cancer. 124, 7, p. 1455-1463 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: Results of Alliance N0874/ABTC 02

Galanis, E., Keith Anderson, S., Miller, C. R., Sarkaria, J. N., Jaeckle, K., Buckner, J. C., Ligon, K. L., Ballman, K. V., Moore, D. F., Nebozhyn, M., Loboda, A., Schiff, D., Ahluwalia, M. S., Lee, E. Q., Gerstner, E. R., Lesser, G. J., Prados, M., Grossman, S. A., Cerhan, J., Giannini, C. & 1 others, Wen, P. Y., Mar 27 2018, In : Neuro-oncology. 20, 4, p. 546-556 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition

Marisol Herrera-Perez, R., Voytik-Harbin, S. L., Sarkaria, J. N., Pollok, K. E., Fishel, M. L. & Rickus, J. L., Mar 2018, In : PloS one. 13, 3, e0194183.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Alisertib demonstrates significant antitumor activity in bevacizumab resistant, patient derived orthotopic models of glioblastoma

Kurokawa, C., Geekiyanage, H., Allen, C., Iankov, I., Schroeder, M., Carlson, B., Bakken, K., Sarkaria, J., Ecsedy, J. A., D’Assoro, A., Friday, B. & Galanis, E., Jan 1 2017, In : Journal of neuro-oncology. 131, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patientderived GBM tumor cells

Tivnan, A., Heilinger, T., Ramsey, J. M., O'Connor, G., Pokorny, J. L., Sarkaria, J. N., Stringer, B. W., Day, B. W., Boyd, A. W., Kim, E. L., Lode, H. N., Cryan, S. A. & Prehn, J. H. M., 2017, In : Oncotarget. 8, 10, p. 16605-16620 16 p.

Research output: Contribution to journalArticle

13 Scopus citations

A TNF-JNK-Axl-ERK signaling axis mediates primary resistance to EGFR inhibition in glioblastoma

Guo, G., Gong, K., Ali, S., Ali, N., Shallwani, S., Hatanpaa, K. J., Pan, E., Mickey, B., Burma, S., Wang, D. H., Kesari, S., Sarkaria, J. N., Zhao, D. & Habib, A. A., Aug 1 2017, In : Nature Neuroscience. 20, 8, p. 1074-1084 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

CD90 expression controls migration and predicts dasatinib response in glioblastoma

Avril, T., Etcheverry, A., Pineau, R., Obacz, J., Jegou, G., Jouan, F., Le Reste, P. J., Hatami, M., Colen, R. R., Carlson, B. L., Decker, P. A., Sarkaria, J. N., Vauléon, E., Chiforeanu, D. C., Clavreul, A., Mosser, J., Chevet, E. & Quillien, V., Dec 1 2017, In : Clinical Cancer Research. 23, 23, p. 7360-7374 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Characterization of relative biological effectiveness for conventional radiation therapy: A comparison of clinical 6 MV X-rays and 137Cs

Howard, M., Beltran, C., Sarkaria, J. & Herman, M. G., Sep 1 2017, In : Journal of Radiation Research. 58, 5, p. 608-613 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Combination therapy in a xenograft model of glioblastoma: Enhancement of the antitumor activity of temozolomide by an MDM2 antagonist

Wang, H., Cai, S., Bailey, B. J., Saadatzadeh, M. R., Ding, J., Tonsing-Carter, E., Georgiadis, T. M., Gunter, T. Z., Long, E. C., Minto, R. E., Gordon, K. R., Sen, S. E., Cai, W., Eitel, J. A., Waning, D. L., Bringman, L. R., Wells, C. D., Murray, M. E., Sarkaria, J. N., Gelbert, L. M. & 5 others, Jones, D. R., Cohen-Gadol, A. A., Mayo, L. D., Shannon, H. E. & Pollok, K. E., Feb 2017, In : Journal of neurosurgery. 126, 2, p. 446-459 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma

McNeill, R. S., Canoutas, D. A., Stuhlmiller, T. J., Dhruv, H. D., Irvin, D. M., Bash, R. E., Angus, S. P., Herring, L. E., Simon, J. M., Skinner, K. R., Limas, J. C., Chen, X., Schmid, R. S., Siegel, M. B., Van Swearingen, A. E. D., Hadler, M. J., Sulman, E. P., Sarkaria, J. N., Anders, C. K., Graves, L. M. & 3 others, Berens, M. E., Johnson, G. L. & Miller, C. R., Nov 1 2017, In : Neuro-oncology. 19, 11, p. 1469-1480 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme

Nagel, Z. D., Kitange, G. J., Gupta, S. K., Joughin, B. A., Chaim, I. A., Mazzucato, P., Lauffenburger, D. A., Sarkaria, J. N. & Samson, L. D., Jan 1 2017, In : Cancer research. 77, 1, p. 198-206 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

Drug delivery to melanoma brain metastases: Can current challenges lead to new opportunities?

Gampa, G., Vaidhyanathan, S., Sarkaria, J. N. & Elmquist, W. F., Sep 2017, In : Pharmacological Research. 123, p. 10-25 16 p.

Research output: Contribution to journalArticle

12 Scopus citations

EGFR signals through a DOCK180-MLK3 axis to drive glioblastoma cell invasion

Misek, S. A., Chen, J., Schroeder, L., Rattanasinchai, C., Sample, A., Sarkaria, J. N. & Gallo, K. A., Aug 1 2017, In : Molecular Cancer Research. 15, 8, p. 1085-1095 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Extracellular Hyaluronic Acid Influences the Efficacy of EGFR Tyrosine Kinase Inhibitors in a Biomaterial Model of Glioblastoma

Pedron, S., Hanselman, J. S., Schroeder, M. A., Sarkaria, J. N. & Harley, B. A. C., Nov 8 2017, In : Advanced Healthcare Materials. 6, 21, 1700529.

Research output: Contribution to journalArticle

16 Scopus citations

Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma

Cosset, É., Ilmjärv, S., Dutoit, V., Elliott, K., von Schalscha, T., Camargo, M. F., Reiss, A., Moroishi, T., Seguin, L., Gomez, G., Moo, J. S., Preynat-Seauve, O., Krause, K. H., Chneiweiss, H., Sarkaria, J. N., Guan, K. L., Dietrich, P. Y., Weis, S. M., Mischel, P. S. & Cheresh, D. A., Dec 11 2017, In : Cancer cell. 32, 6, p. 856-868.e5

Research output: Contribution to journalArticle

44 Scopus citations

Heterogeneous binding and central nervous system distribution of the multitargeted kinase inhibitor ponatinib restrict orthotopic efficacy in a patient-derived xenograft model of glioblastoma

Laramy, J. K., Kim, M., Gupta, S. K., Parrish, K. E., Zhang, S., Bakken, K. K., Carlson, B. L., Mladek, A. C., Ma, D. J., Sarkaria, J. N. & Elmquist, W. F., Nov 2017, In : Journal of Pharmacology and Experimental Therapeutics. 363, 2, p. 136-147 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Immunovirotherapy with measles virus strains in combination with anti-PD-1 antibody blockade enhances antitumor activity in glioblastoma treatment

Hardcastle, J., Mills, L., Malo, C. S., Jin, F., Kurokawa, C., Geekiyanage, H., Schroeder, M., Sarkaria, J., Johnson, A. J. & Galanis, E., Apr 1 2017, In : Neuro-oncology. 19, 4, p. 493-502 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Inhibiting DNA-PKCS radiosensitizes human osteosarcoma cells

Mamo, T., Mladek, A. C., Shogren, K. L., Gustafson, C., Gupta, S. K., Riester, S. M., Maran, A., Galindo, M., van Wijnen, A. J., Sarkaria, J. N. & Yaszemski, M. J., Apr 29 2017, In : Biochemical and Biophysical Research Communications. 486, 2, p. 307-313 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Macropinocytosis of bevacizumab by glioblastoma cells in the perivascular niche affects their survival

Müller-Greven, G., Carlin, C. R., Burgett, M. E., Ahluwalia, M. S., Lauko, A., Nowacki, A. S., Herting, C. J., Qadan, M. A., Bredel, M., Toms, S. A., Lathia, J. D., Hambardzumyan, D., Sarkaria, J. N., Hamerlik, P. & Gladson, C. L., Nov 15 2017, In : Clinical Cancer Research. 23, 22, p. 7059-7071 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix

Heim, J. B., Squirewell, E. J., Neu, A., Zocher, G., Sominidi-Damodaran, S., Wyles, S. P., Nikolova, E., Behrendt, N., Saunte, D. M., Lock-Andersen, J., Gaonkar, K. S., Yan, H., Sarkaria, J. N., Krendel, M., Van Deursen, J., Sprangers, R., Stehle, T., Böttcher, R. T., Lee, J. H., Ordog, T. & 1 others, Meves, A., Apr 11 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 15, p. 3933-3938 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Radiogenomics to characterize regional genetic heterogeneity in glioblastoma

Hu, L. S., Ning, S., Eschbacher, J. M., Baxter, L. C., Gaw, N., Ranjbar, S., Plasencia, J., Dueck, A. C., Peng, S., Smith, K. A., Nakaji, P., Karis, J. P., Quarles, C. C., Wu, T., Loftus, J. C., Jenkins, R. B., Sicotte, H., Kollmeyer, T. M., O'Neill, B. P., Elmquist, W. & 7 others, Hoxworth, J. M., Frakes, D., Sarkaria, J., Swanson, K. R., Tran, N. L., Li, J. & Mitchell, J. R., 2017, In : Neuro-oncology. 19, 1, p. 128-137 10 p.

Research output: Contribution to journalArticle

73 Scopus citations
4 Scopus citations

Restricted delivery of talazoparib across the blood–brain barrier limits the sensitizing effects of PARP inhibition on temozolomide therapy in glioblastoma

Kizilbash, S. H., Gupta, S. K., Chang, K., Kawashima, R., Parrish, K. E., Carlson, B. L., Bakken, K. K., Mladek, A. C., Schroeder, M. A., Decker, P. A., Kitange, G. J., Shen, Y., Feng, Y., Protter, A. A., Elmquist, W. F. & Sarkaria, J. N., Dec 2017, In : Molecular cancer therapeutics. 16, 12, p. 2735-2746 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Spatially graded hydrogels for preclinical testing of glioblastoma anticancer therapeutics

Pedron, S., Polishetty, H., Pritchard, A. M., Mahadik, B. P., Sarkaria, J. N. & Harley, B. A. C., Sep 1 2017, In : MRS Communications. 7, 3, p. 442-449 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways

Bijangi-Vishehsaraei, K., Saadatzadeh, M. R., Wang, H., Nguyen, A., Kamocka, M. M., Cai, W., Cohen-Gadol, A. A., Halum, S. L., Sarkaria, J. N., Pollok, K. E. & Safa, A. R., Dec 2017, In : Journal of neurosurgery. 127, 6, p. 1219-1230 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Challenges in the Delivery of Therapies to Melanoma Brain Metastases

Gampa, G., Vaidhyanathan, S., Wilken-Resman, B., Parrish, K. E., Markovic, S. N., Sarkaria, J. N. & Elmquist, W. F., Dec 1 2016, In : Current Pharmacology Reports. 2, 6, p. 309-325 17 p.

Research output: Contribution to journalReview article

6 Scopus citations

Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma

Gupta, S. K., Kizilbash, S. H., Carlson, B. L., Mladek, A. C., Boakye-Agyeman, F., Bakken, K. K., Pokorny, J. L., Schroeder, M. A., Decker, P. A., Cen, L., Eckel-Passow, J. E., Sarkar, G., Ballman, K. V., Reid, J. M., Jenkins, R. B., Verhaak, R. G., Sulman, E. P., Kitange, G. J. & Sarkaria, J. N., May 1 2016, In : Journal of the National Cancer Institute. 108, 5

Research output: Contribution to journalArticle

40 Scopus citations

Factors influencing the central nervous system distribution of a novel phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor GSK2126458: Implications for overcoming resistance with combination therapy for melanoma brain metastasess

Vaidhyanathan, S., Wilken-Resman, B., Ma, D. J., Parrish, K. E., Mittapalli, R. K., Carlson, B. L., Sarkaria, J. N. & Elmquist, W. F., Feb 1 2016, In : Journal of Pharmacology and Experimental Therapeutics. 356, 2, p. 251-259 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth

Hashizume, R., Zhang, A., Mueller, S., Prados, M. D., Lulla, R. R., Goldman, S., Saratsis, A. M., Mazar, A. P., Stegh, A. H., Cheng, S. Y., Horbinski, C., Haas-Kogan, D. A., Sarkaria, J. N., Waldman, T. & James, C. D., Nov 1 2016, In : Neuro-oncology. 18, 11, p. 1519-1528 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

InsR/IGF1R pathway mediates resistance to EGFR inhibitors in glioblastoma

Ma, Y., Tang, N., Thompson, R. C., Mobley, B. C., Clark, S. W., Sarkaria, J. N. & Wang, J., Apr 1 2016, In : Clinical Cancer Research. 22, 7, p. 1767-1776 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation

Gong, Y., Ma, Y., Sinyuk, M., Loganathan, S., Thompson, R. C., Sarkaria, J. N., Chen, W., Lathia, J. D., Mobley, B. C., Clark, S. W. & Wang, J., Jan 1 2016, In : Neuro-oncology. 18, 1, p. 48-57 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Network Modeling Identifies Patient-specific Pathways in Glioblastoma

Tuncbag, N., Milani, P., Pokorny, J. L., Johnson, H., Sio, T. T., Dalin, S., Iyekegbe, D. O., White, F. M., Sarkaria, J. N. & Fraenkel, E., Jun 29 2016, In : Scientific reports. 6, 28668.

Research output: Contribution to journalArticle

16 Scopus citations

Quantitative phosphoproteomics reveals wee1 kinase as a therapeutic target in a model of proneural glioblastoma

Lescarbeau, R. S., Lei, L., Bakken, K. K., Sims, P. A., Sarkaria, J. N., Canoll, P. & White, F. M., Jun 2016, In : Molecular cancer therapeutics. 15, 6, p. 1332-1343 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins

Kitange, G. J., Mladek, A. C., Schroeder, M. A., Pokorny, J. C., Carlson, B. L., Zhang, Y., Nair, A. A., Lee, J. H., Yan, H., Decker, P. A., Zhang, Z. & Sarkaria, J. N., Mar 22 2016, In : Cell reports. 14, 11, p. 2587-2598 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

SGEF is regulated via TWEAK/Fn14/NF-κB signaling and promotes survival by modulation of the DNA repair response to temozolomide

Fortin Ensign, S. P., Roos, A., Mathews, I. T., Dhruv, H. D., Tuncali, S., Sarkaria, J. N., Symons, M. H., Loftus, J. C., Berens, M. E. & Tran, N. L., Mar 2016, In : Molecular Cancer Research. 14, 3, p. 302-312 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Strategies to improve delivery of anticancer drugs across the blood-brain barrier to treat glioblastoma

Oberoi, R. K., Parrish, K. E., Sio, T. T., Mittapalli, R. K., Elmquist, W. F. & Sarkaria, J. N., Jan 1 2016, In : Neuro-oncology. 18, 1, p. 27-36 10 p.

Research output: Contribution to journalReview article

100 Scopus citations
2015

A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K

Ma, D. J., Galanis, E., Anderson, S. K., Schiff, D., Kaufmann, T. J., Peller, P. J., Giannini, C., Brown, P. D., Uhm, J. H., McGraw, S., Jaeckle, K. A., Flynn, P. J., Ligon, K. L., Buckner, J. C. & Sarkaria, J. N., Sep 1 2015, In : Neuro-oncology. 17, 9, p. 1261-1269 9 p.

Research output: Contribution to journalArticle

63 Scopus citations

Brain Malignancy Steering Committee clinical trials planning workshop: Report from the Targeted Therapies Working Group

Alexander, B. M., Galanis, E., Yung, W. K. A., Ballman, K. V., Boyett, J. M., Cloughesy, T. F., Degroot, J. F., Huse, J. T., Mann, B., Mason, W., Mellinghoff, I. K., Mikkelsen, T., Mischel, P. S., O'Neill, B. P., Prados, M. D., Sarkaria, J. N., Tawab-Amiri, A., Trippa, L., Ye, X., Ligon, K. L. & 2 others, Berry, D. A. & Wen, P. Y., Feb 1 2015, In : Neuro-oncology. 17, 2, p. 180-188 9 p.

Research output: Contribution to journalReview article

23 Scopus citations

CNS Anticancer Drug Discovery and Development Conference White Paper

Levin, V. A., Tonge, P. J., Gallo, J. M., Birtwistle, M. R., Dar, A. C., Iavarone, A., Paddison, P. J., Heffron, T. P., Elmquist, W. F., Lachowicz, J. E., Johnson, T. W., White, F. M., Sul, J., Smith, Q. R., Shen, W., Sarkaria, J. N., Samala, R., Wen, P. Y., Berry, D. A. & Petter, R. C., May 24 2015, In : Neuro-oncology. 17, p. vi1-vi26

Research output: Contribution to journalReview article

19 Scopus citations

Convertible MRI contrast: Sensing the delivery and release of anti-glioma nano-drugs

Zhang, L., Zhang, Z., Mason, R. P., Sarkaria, J. N. & Zhao, D., May 12 2015, In : Scientific reports. 5, 9874.

Research output: Contribution to journalArticle

24 Scopus citations

Critical functions of RhoB in support of glioblastoma tumorigenesis

Ma, Y., Gong, Y., Cheng, Z., Loganathan, S., Kao, C., Sarkaria, J. N., Abel, T. W. & Wang, J., 2015, In : Neuro-oncology. 17, 4, p. 516-525 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Dasatinib in recurrent glioblastoma: Failure as a teacher

Schiff, D. & Sarkaria, J., Jul 1 2015, In : Neuro-oncology. 17, 7, p. 910-911 2 p.

Research output: Contribution to journalShort survey

14 Scopus citations

Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma

Becker, C. M., Oberoi, R. K., McFarren, S. J., Muldoon, D. M., Pafundi, D. H., Pokorny, J. L., Brinkmann, D. H., Ohlfest, J. R., Sarkaria, J. N., Largaespada, D. A. & Elmquist, W. F., Sep 1 2015, In : Neuro-oncology. 17, 9, p. 1210-1219 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Effective treatment of established GL261 murine gliomas through picornavirus vaccination-enhanced tumor antigen-specific CD8+ T cell responses

Renner, D. N., Jin, F., Litterman, A. J., Balgeman, A. J., Hanson, L. M., Gamez, J. D., Chae, M., Carlson, B. L., Sarkaria, J. N., Parney, I. F., Ohlfest, J. R., Pirko, I., Pavelko, K. D. & Johnson, A. J., May 1 2015, In : PloS one. 10, 5, e0125565.

Research output: Contribution to journalArticle

15 Scopus citations