Jane Zhu, MD, PhD

Assistant Professor

  • 557 Citations
  • 9 h-Index
20062018
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  • 1 Similar Profiles
Zebrafish Medicine & Life Sciences
Neuroblastoma Medicine & Life Sciences
Tumors Chemical Compounds
Neoplasms Medicine & Life Sciences
Monomeric GTP-Binding Proteins Medicine & Life Sciences
Oncogenes Medicine & Life Sciences
Embryonic Development Medicine & Life Sciences
Morpholinos Medicine & Life Sciences

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Research Output 2006 2018

  • 557 Citations
  • 9 h-Index
  • 16 Article
  • 2 Chapter
  • 1 Review article
5 Citations

MYC drives a subset of high-risk pediatric neuroblastomas and is activated through mechanisms including enhancer hijacking and focal enhancer amplification

Zimmerman, M. W., Liu, Y., He, S., Durbin, A. D., Abraham, B. J., Easton, J., Shao, Y., Xu, B., Zhu, S., Zhang, X., Li, Z., Weichert-Leahey, N., Young, R. A., Zhang, J. & Look, A. T., Mar 1 2018, In : Cancer Discovery. 8, 3, p. 320-335 16 p.

Research output: Contribution to journalArticle

Neuroblastoma
Pediatrics
Oncogenes
Genes
Genetic Translocation
3 Citations

Critical Role for GAB2 in Neuroblastoma Pathogenesis through the Promotion of SHP2/MYCN Cooperation

Zhang, X., Dong, Z., Zhang, C., Ung, C. Y., He, S., Tao, T., Oliveira, A. M., Meves, A., Ji, B. D., Look, A. T., Li, H., Neel, B. G. & Zhu, S., Mar 21 2017, In : Cell Reports. 18, 12, p. 2932-2942 11 p.

Research output: Contribution to journalArticle

Neuroblastoma
Tumors
Fish
SH2 Domain-Containing Protein Tyrosine Phosphatases
Penetrance
10 Citations

LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis

Zhu, S., Zhang, X., Weichert-Leahey, N., Dong, Z., Zhang, C., Lopez, G., Tao, T., He, S., Wood, A. C., Oldridge, D., Ung, C. Y., van Ree, J. H., Khan, A., Salazar, B. M., Lummertz da Rocha, E., Zimmerman, M. W., Guo, F., Cao, H., Hou, X., Weroha, S. J. & 8 othersPerez-Atayde, A. R., Neuberg, D. S., Meves, A., Mc Niven, M. A., Van Deursen, J., Li, H., Maris, J. M. & Look, A. T., Sep 11 2017, In : Cancer Cell. 32, 3, p. 310-323.e5

Research output: Contribution to journalArticle

Neuroblastoma
Neoplasm Metastasis
Zebrafish
Oncogenes
Extracellular Matrix
3 Citations

Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer Networks

Ghanat Bari, M., Ung, C. Y., Zhang, C., Zhu, S. & Li, H., Dec 1 2017, In : Scientific Reports. 7, 1, 6993.

Research output: Contribution to journalArticle

Neoplasm Genes
MHC Class II Genes
Genes
Neoplasms
MHC Class I Genes
3 Citations

The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma

Tao, T., Sondalle, S. B., Shi, H., Zhu, S., Perez-Atayde, A. R., Peng, J., Baserga, S. J. & Look, A. T., Jul 6 2017, In : Oncogene. 36, 27, p. 3852-3867 16 p.

Research output: Contribution to journalArticle

Ribosomal RNA
Neuroblastoma
RNA Precursors
Zebrafish
Small Ribosome Subunits