• 22779 Citations
  • 71 Scopus h-Index
1980 …2019
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Fingerprint Dive into the research topics where Jan Van Deursen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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M Phase Cell Cycle Checkpoints Medicine & Life Sciences
Aneuploidy Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cell Aging Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Chromosomal Instability Medicine & Life Sciences
Chromosomes Medicine & Life Sciences
Chromosome Segregation Medicine & Life Sciences

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Projects 1980 2019

Carcinogenesis
Phenotype
Neoplasms
Cell Aging
Neoplasm Metastasis
Chromosome Segregation
Neoplasms
Mitosis
PDZ Domains
Phosphotransferases
Chromosomal Instability
Carcinogenesis
Aneuploidy
Neoplasms
M Phase Cell Cycle Checkpoints
M Phase Cell Cycle Checkpoints
Neoplasms
Aneuploidy
Growth
Chromosomal Instability

Research Output 1986 2019

1 Citation (Scopus)

Acceleration of β Cell Aging Determines Diabetes and Senolysis Improves Disease Outcomes

Aguayo-Mazzucato, C., Andle, J., Lee, T. B., Midha, A., Talemal, L., Chipashvili, V., Hollister-Lock, J., Van Deursen, J., Weir, G. & Bonner-Weir, S., Jul 2 2019, In : Cell Metabolism. 30, 1, p. 129-142.e4

Research output: Contribution to journalArticle

Cell Aging
Type 2 Diabetes Mellitus
Insulin Resistance
Metabolome
High Fat Diet
1 Citation (Scopus)

Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice

Aziz, K., Limzerwala, J. F., Sturmlechner, I., Hurley, E., Zhang, C., Jeganathan, K. B., Nelson, G., Bronk, S., Fierro Velasco, R. O., van Deursen, E. J., O'Brien, D. R., Kocher, J-P., Youssef, S. A., van Ree, J. H., de Bruin, A., van den Bos, H., Spierings, D. C. J., Foijer, F., van de Sluis, B., Roberts, L. R. & 3 others, Gores, G. J., Li, H. & Van Deursen, J., Jul 1 2019, In : Gastroenterology. 157, 1, p. 210-226.e12

Research output: Contribution to journalArticle

Chromosomal Instability
Cyclins
Liver
Neoplasms
Chromosomes

Crystallizing BubR1’s kinase activity

Limzerwala, J. F. & Van Deursen, J., Jan 1 2019, In : Cell Research.

Research output: Contribution to journalComment/debate

Open Access

Inhibition of ‘jumping genes’ promotes healthy ageing

Childs, B. & Van Deursen, J., Feb 7 2019, In : Nature. 566, 7742, p. 46-48 3 p.

Research output: Contribution to journalArticle

Open Access
Interspersed Repetitive Sequences
Retroelements
Genome
Health

Nearly complete deletion of BubR1 causes microcephaly through shortened mitosis and massive cell death

Simmons, A. J., Park, R., Sterling, N. A., Jang, M-H. D., Van Deursen, J., Yen, T. J., Cho, S. H. & Kim, S., Jun 1 2019, In : Human molecular genetics. 28, 11, p. 1822-1836 15 p.

Research output: Contribution to journalArticle

Microcephaly
M Phase Cell Cycle Checkpoints
Mitosis
Cell Death
Chromosome Segregation