• 12951 Citations
  • 60 Scopus h-Index
1973 …2021

Research output per year

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Research Output

1973

Analyses for roll force and torque in ring rolling, with some supporting experiments

Hawkyard, J. B., Johnson, W., Kirkland, J. & Appleton, E., Nov 1973, In : International Journal of Mechanical Sciences. 15, 11, p. 873-893 21 p.

Research output: Contribution to journalArticle

121 Scopus citations
1976

Hypothalamic serotonin modulates the ACTH response to repeated stress

Van Loon, G. R., Shum, A. & Kirkland, J., Jan 1 1976, In : Clinical Research. 24, 5, p. 663A

Research output: Contribution to journalArticle

1981

Bacteriuria and Survival in Old Age

Kirkland, J. L., Robinson, J. M., Dontas, A. S., Kasviki-Charvati, P., Papanayiotou, P. C. & Marketos, S. G., Sep 3 1981, In : New England Journal of Medicine. 305, 10, p. 586-587 2 p.

Research output: Contribution to journalLetter

5 Scopus citations
1983

A longitudinal study of the prognostic significance of ventricular ectopic beats in the elderly

Kirkland, J. L., Lye, M., Faragher, E. B. & dos Santos, A. G. R., Jan 1 1983, In : Gerontology. 29, 3, p. 199-201 3 p.

Research output: Contribution to journalArticle

12 Scopus citations

Constipation in long-stay elderly patients: Its treatment and prevention by lactulose, poloxalkol-dihydroxyanthroquinolone and phosphate enemas

Brocklehurst, J. C., Kirkland, J. L., Martin, J. & Ashford, J., Jan 1 1983, In : Gerontology. 29, 3, p. 181-184 4 p.

Research output: Contribution to journalArticle

27 Scopus citations

Indican excretion in the elderly

Kirkland, J. L., Vargas, E. & Lye, M., Jan 1 1983, In : Postgraduate Medical Journal. 59, 697, p. 717-719 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

Patterns of urine flow and electrolyte excretion in healthy elderly people

Kirkland, J. L., Lye, M., Levy, D. W. & Banerjee, A. K., Dec 1 1983, In : British medical journal. 287, 6406, p. 1665-1667 3 p.

Research output: Contribution to journalArticle

144 Scopus citations

Polyuria and Inappropriate Secretion of Arginine Vasopressin in Hypothalamic Sarcoidosis

Kirkland, J. L., Pearson, D. J., Goddard, C. & Davies, I., Feb 1983, In : Journal of Clinical Endocrinology and Metabolism. 56, 2, p. 269-272 4 p.

Research output: Contribution to journalArticle

16 Scopus citations
1984

Adipocyte Hormone Responsiveness and Aging in the Rat: Problems in the Interpretation of Aging Research

KIRKLAND, JAMES. L. & DAX, ELIZABETH. M., Mar 1984, In : Journal of the American Geriatrics Society. 32, 3, p. 219-228 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Analysis of circadian rhythms by fitting a least squares sine curve

Hickey, D. S., Kirkland, J. L., Lucas, S. B. & Lye, M., 1984, In : Computers in Biology and Medicine. 14, 2, p. 217-223 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

PLASMA ARGININE VASOPRESSIN IN DEHYDRATED ELDERLY PATIENTS

KIRKLAND, J., LYE, M., GODDARD, C., VARGAS, E. & DAVIES, I., Apr 1984, In : Clinical Endocrinology. 20, 4, p. 451-456 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Stimulation of human fat cell adenylate cyclase by GDP and guanosine 5'-O-(2-thiodiphosphate)

Schneyer, C. R., Pineyro, M. A., Kirkland, J. L. & Gregerman, R. I., Jan 1 1984, In : Journal of Biological Chemistry. 259, 11, p. 7038-7044 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
1987

Hormone‐sensitive adenylyl cyclase in preadipocytes cultured from adipose tissue: Comparison with 3T3‐L1 cells and adipocytes

Kirkland, J. L., Piñeyro, M. A., Lu, Z. & Gregerman, R. I., Dec 1987, In : Journal of Cellular Physiology. 133, 3, p. 449-460 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

The insurability of elderly patients.

Kirkland, J. L., Jan 1 1987, In : Transactions of the Association of Life Insurance Medical Directors of America. 70, p. 135-145 11 p.

Research output: Contribution to journalArticle

1988
11 Scopus citations
1989

Evolution and ageing

Kirkland, J. L., Jan 1 1989, In : Genome. 31, 1, p. 398-405 8 p.

Research output: Contribution to journalReview article

10 Scopus citations
11 Scopus citations

Varying capacities for replication of rat adipocyte precursor clones and adipose tissue growth

Wang, H., Kirkland, J. L. & Hollenberg, C. H., Jan 1 1989, In : Journal of Clinical Investigation. 83, 5, p. 1741-1746 6 p.

Research output: Contribution to journalArticle

Open Access
55 Scopus citations
1990

Age, anatomic site, and the replication and differentiation of adipocyte precursors

Kirkland, J. L., Hollenberg, C. H. & Gillon, W. S., Mar 20 1990, In : American Journal of Physiology - Cell Physiology. 258, 2 27-2, p. C206-C210

Research output: Contribution to journalArticle

147 Scopus citations
1992

Effect of hypophysectomy on rat preadipocyte replication and differentiation

Kirkland, J. L., Hollenberg, C. H., Gillon, W. & Kindler, S., Dec 1992, In : Endocrinology. 131, 6, p. 2769-2773 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

The biochemistry of mammalian senescence

Kirkland, J. L., Apr 1992, In : Clinical Biochemistry. 25, 2, p. 61-75 15 p.

Research output: Contribution to journalReview article

22 Scopus citations
1993

Ageing, differentiation, and gene expression in rat epididymal preadipocytes.

Kirkland, J. L., Hollenberg, C. H. & Gillon, W. S., Jan 1 1993, In : Biochemistry and cell biology = Biochimie et biologie cellulaire. 71, 11-12, p. 556-561 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Effects of aging on ribosomal protein L7 messenger RNA levels in cultured rat preadipocytes

Kirkland, J. L., Hollenberg, C. H. & Gillon, W. S., Jan 1 1993, In : Experimental Gerontology. 28, 6, p. 557-563 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Two Preadipocyte Subtypes Cloned from Human Omental Fat

Kirkland, J. L., Hollenberg, C. H. & Gillon, W. S., Mar 1993, In : Obesity research. 1, 2, p. 87-91 5 p.

Research output: Contribution to journalArticle

11 Scopus citations
1994

Effects of age and anatomic site on preadipocyte number in rat fat depots

Kirkland, J. L., Hollenberg, C. H., Kindler, S. & Gillon, W. S., Jan 1 1994, In : Journals of Gerontology. 49, 1, p. B31-B35

Research output: Contribution to journalArticle

70 Scopus citations

Long-chain fatty acids decrease lipoprotein lipase activity of cultured rat adipocyte precursors

Kirkland, J. L., Hollenberg, C. H., Kindler, S. & Roncari, D. A. K., Feb 1994, In : Metabolism. 43, 2, p. 144-151 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
1995

Cluster deaths in long-term care institutions: An investigation of excess deaths in two Ontario institutions

Naglie, G., Goldlist, B., Kirkland, J., Gordon, M., Klapecki, K., Young, J. & Clark, P., Jan 1 1995, In : Canadian Journal of Public Health. 86, 2, p. 120-123 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Do Geriatric Programs Decrease Long‐Term Use of Acute Care Beds?

Brymer, C. D., Kohm, C. A., Naglie, G., Shekter‐Wolfson, L., Zorzitto, M. L., O'Rourke, K. & Kirkland, J. L., Aug 1995, In : Journal of the American Geriatrics Society. 43, 8, p. 885-889 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
1996

Effects of fat depot site on differentiation-dependent gene expression in rat preadipocytes

Kirkland, J. L., Hollenberg, C. H. & Gillon, W. S., Apr 22 1996, In : International Journal of Obesity. 20, SUPPL. 3, p. S102-S107

Research output: Contribution to journalArticle

50 Scopus citations

Glomerular dysfunction in the aging Fischer 344 rat is associated with excessive growth and normal mesangial cell function

McDermott, G. F., Ingram, A., Scholey, J., Kirkland, J. L. & Whiteside, C. I., Mar 1996, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 51, 2, p. M80-M85

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Increasing vimentin expression associated with differentiation of human and rat preadipocytes

Teichert-Kuliszewska, K., Hamilton, B. S., Roncari, D., Kirkland, J. L., Gillon, W. S., Deitel, M. & Hollenberg, C. H., Apr 22 1996, In : International Journal of Obesity. 20, SUPPL. 3, p. S108-S113

Research output: Contribution to journalArticle

15 Scopus citations
1997

Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes

Brown, N. F., Hill, J. K., Esser, V., Kirkland, J. L., Corkey, B. E., Foster, D. W. & McGarry, J. D., Jan 1 1997, In : Biochemical Journal. 327, 1, p. 225-231 7 p.

Research output: Contribution to journalArticle

90 Scopus citations
81 Scopus citations
1998

A 13C nuclear magnetic resonance study of free fatty acid incorporation in acylated lipids in differentiating preadipocytes

Guo, W., Kirkland, J. L., Corkey, B. & Hamilton, J. A., Jun 18 1998, In : Lipids. 33, 5, p. 449-454 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Inhibitors of preadipocyte replication: opportunities for the treatment of obesity.

Kirkland, J. L. & Hollenberg, C. H., 1998, In : Progress in molecular and subcellular biology. 20, p. 177-195 19 p.

Research output: Contribution to journalReview article

6 Scopus citations
1999

Commentary: Aging, differentiation-dependent gene expression, and fat cell function

Kirkland, J. L., Hotta, K., Bodkin, N. L., Gustafson, T. A., Yoshioka, S., Ortmeyer, H. K. & Hansen, B. C., Jun 9 1999, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 54, 5, p. B189-B191

Research output: Contribution to journalComment/debate

2 Scopus citations

Incorporation of [1-13C]oleate into cellular triglycerides in differentiating 3T3L1 cells

Guo, W., Choi, J. K., Kirkland, J. L., Corkey, B. E. & Hamilton, J. A., Sep 28 1999, In : Lipids. 34, 8, p. 825-831 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2000

Esterification of free fatty acids in adipocytes: A comparison between octanoate and oleate

Guo, W., Choi, J. K., Kirkland, J. L., Corkey, B. E. & Hamilton, J. A., Jul 15 2000, In : Biochemical Journal. 349, 2, p. 463-471 9 p.

Research output: Contribution to journalArticle

28 Scopus citations
2001

Altered expression of C/EBP family members results in decreased adipogenesis with aging

Karagiannides, I., Tchkonia, T., Dobson, D. E., Steppan, C. M., Cummins, P., Chan, G., Salvatori, K., Hadzopoulou-Cladaras, M. & Kirkland, J. L., Jul 3 2001, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 280, 6 49-6, p. R1772-R1780

Research output: Contribution to journalArticle

115 Scopus citations

Different fat depots are distinct mini-organs

Tchkonia, T., Karagiannides, I., Armour Forse, R. & Kirkland, J. L., Jan 1 2001, In : Current Opinion in Endocrinology and Diabetes. 8, 5, p. 227-234 8 p.

Research output: Contribution to journalReview article

12 Scopus citations

Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes

Caserta, F., Tchkonia, T., Civelek, V. N., Prentki, M., Brown, N. F., McGarry, J. D., Forse, R. A., Corkey, B. E., Hamilton, J. A. & Kirkland, J. L., Feb 1 2001, In : American Journal of Physiology - Endocrinology and Metabolism. 280, 2 43-2, p. E238-E247

Research output: Contribution to journalArticle

73 Scopus citations

Nutritional risk in an urban homebound older population the nutrition and healthy aging project

Millen, B. E., Silliman, R. A., Cantey-Kiser, J., Copenhafer, D. L., Ewart, C. V., Ritchie, C. S., Quatromoni, P. A., Kirkland, J. L., Chipkin, S. R., Fearon, N. A., Lund, M. E., Garcia, R. I. & Barry, P. P., Dec 1 2001, In : Journal of Nutrition, Health and Aging. 5, 4, p. 269-277 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Subject recruitment, retention and protocol feasibility in a prospective study of nutritional risk among urban, frail homebound elders

Ewart, C. V., Fearon, N. A., Lund, M. E., Martin, B., Kirkland, J. L., Ritchie, C. S., Quatromoni, P. A., Silliman, R. A. & Millen, B. E., Nov 2001, In : Journal of Nutrition for the Elderly. 21, 1, p. 1-21 21 p.

Research output: Contribution to journalArticle

4 Scopus citations
2002

Adipogenesis and aging: Does aging make fat go MAD?

Kirkland, J. L., Tchkonia, T., Pirtskhalava, T., Han, J. & Karagiannides, I., Jun 1 2002, In : Experimental Gerontology. 37, 6, p. 757-767 11 p.

Research output: Contribution to journalReview article

225 Scopus citations

Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes

Tchkonia, T., Giorgadze, N., Pirtskhalava, T., Tchoukalova, Y., Karagiannides, I., Armour Forse, R., Deponte, M., Stevenson, M., Guo, W., Han, J., Waloga, G., Lash, T. L., Jensen, M. D. & Kirkland, J. L., Jul 2 2002, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 282, 5 51-5, p. R1286-R1296

Research output: Contribution to journalArticle

202 Scopus citations

Interdisciplinary inpatient care for elderly people with hip fracture: A randomized controlled trial

Naglie, G., Tansey, C., Kirkland, J. L., Ogilvie-Harris, D. J., Detsky, A. S., Etchells, E., Tomlinson, G., O'Rourke, K. & Goldlist, B., Jul 17 2002, In : CMAJ. 167, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

126 Scopus citations

Octanoate attenuates adipogenesis in 3T3-L1 preadipocytes

Han, J., Farmer, S. R., Kirkland, J. L., Corkey, B. E., Yoon, R., Pirtskhalava, T., Ido, Y. & Guo, W., May 20 2002, In : Journal of Nutrition. 132, 5, p. 904-910 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

The biology of senescence: Potential for prevention of disease

Kirkland, J. L., Aug 1 2002, In : Clinics in Geriatric Medicine. 18, 3, p. 383-405 23 p.

Research output: Contribution to journalReview article

21 Scopus citations
2003

Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats

Han, J., Hamilton, J. A., Kirkland, J. L., Corkey, B. E. & Guo, W., Jan 1 2003, In : Obesity research. 11, 6, p. 734-744 11 p.

Research output: Contribution to journalArticle

83 Scopus citations
2005

Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots

Tchkonia, T., Tchoukalova, Y. D., Giorgadze, N., Pirtskhalava, T., Karagiannides, I., Forse, R. A., Koo, A., Stevenson, M., Chinnappan, D., Cartwright, A., Jensen, M. D. & Kirkland, J. L., Jan 1 2005, In : American Journal of Physiology - Endocrinology and Metabolism. 288, 1 51-1, p. E267-E277

Research output: Contribution to journalArticle

167 Scopus citations