Irina V Kovtun, PhD

  • 1221 Citations
  • 15 Scopus h-Index
20002019
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Fingerprint Dive into the research topics where Irina V Kovtun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Huntington Disease Medicine & Life Sciences
Trinucleotide Repeats Medicine & Life Sciences
Prostatic Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
DNA Medicine & Life Sciences
DNA Glycosylases Medicine & Life Sciences
Poisons Medicine & Life Sciences

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Projects 2008 2013

Trinucleotide Repeats
Cell Cycle Checkpoints
Trinucleotide Repeat Expansion
Germ Cells
Mutation
Exanthema
Epidermal Growth Factor Receptor
Vitamin K 3
Neoplasms
Skin

Research Output 2000 2019

  • 1221 Citations
  • 15 Scopus h-Index
  • 24 Article
  • 1 Chapter

Large Chromosomal Rearrangements Yield Biomarkers to Distinguish Low-Risk From Intermediate- and High-Risk Prostate Cancer

Vasmatzis, G., Kosari, F., Murphy, S. J., Terra, S., Kovtun, I. V., Harris, F. R., Zarei, S., Smadbeck, J., Johnson, S. H., Gaitatzes, A. G., Therneau, T. M., Rangel, L. J., Knudson, R. A., Greipp, P. T., Sukov, W. R., Knutson, D. L., Kloft-Nelson, S. M., Karnes, R. J. & Cheville, J., Jan 1 2019, In : Mayo Clinic Proceedings. 94, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Biomarkers
Area Under Curve
Neoplasm Grading
Needle Biopsy
2 Citations (Scopus)

Targeting HER2 in patient-derived xenograft ovarian cancer models sensitizes tumors to chemotherapy

Harris, F. R., Zhang, P., Yang, L., Hou, X., Leventakos, K., Weroha, S. J., Vasmatzis, G. & Kovtun, I. V., Jan 1 2018, (Accepted/In press) In : Molecular Oncology.

Research output: Contribution to journalArticle

Heterografts
Ovarian Neoplasms
Drug Therapy
Neoplasms
Therapeutics
4 Citations (Scopus)

EGFR mediates activation of RET in lung adenocarcinoma with neuroendocrine differentiation characterized by ASCL1 expression

Bhinge, K., Yang, L., Terra, S., Nasir, A., Muppa, P., Aubry, M. C., Yi, J., Janaki, N., Kovtun, I. V., Murphy, S. J., Halling, G., Rahi, H., Mansfield, A., De Andrade, M., Yang, P., Vasmatzis, G., Peikert, T. D. & Kosari, F., 2017, In : Oncotarget. 8, 16, p. 27155-27165 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Adenocarcinoma
Epidermal Growth Factor
Protein Isoforms
Phosphorylation
21 Citations (Scopus)

Quantification of Somatic Chromosomal Rearrangements in Circulating Cell-Free DNA from Ovarian Cancers

Harris, F. R., Kovtun, I. V., Smadbeck, J., Multinu, F., Jatoi, A., Kosari, F., Kalli, K. R., Murphy, S. J., Halling, G. C., Johnson, S. H., Liu, M. C., Mariani, A. & Vasmatzis, G., Jul 20 2016, In : Scientific Reports. 6, 29831.

Research output: Contribution to journalArticle

Ovarian Neoplasms
DNA
Neoplasms
Polymerase Chain Reaction
Tumor Burden
12 Citations (Scopus)

Chromosomal catastrophe is a frequent event in clinically insignificant prostate cancer

Kovtun, I. V., Murphy, S. J., Johnson, S. H., Cheville, J. C. & Vasmatzis, G., 2015, In : Oncotarget. 6, 30, p. 29087-29096 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Neoplasms
Neoplasm Grading
Prostatic Intraepithelial Neoplasia
Chromothripsis