Hirohito Kita, MD

  • 13400 E Shea Blvd, Mayo Clinic Arizona, MCCRB Room 2-213

    85259 Scottsdale

    United States

  • 14965 Citations
  • 68 Scopus h-Index
1984 …2020

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Article
1990

Regulatory effect of cytokines on eosinophil degranulation

Fujisawa, T., Abu-Ghazaleh, R., Kita, H., Sanderson, C. J. & Gleich, G. J., Jan 1 1990, In : Journal of Immunology. 144, 2, p. 642-646 5 p.

Research output: Contribution to journalArticle

298 Scopus citations
1991

Administration of interleukin-2 (IL-2) results in increased plasma concentrations of IL-5 and eosinophilia in patients with cancer

Van Haelst Pisani, C., Kovach, J. S., Kita, H., Leiferman, K. M., Gleich, G. J., Silver, J. E., Dennin, R. & Abrams, J. S., 1991, In : Blood. 78, 6, p. 1538-1544 7 p.

Research output: Contribution to journalArticle

Open Access
85 Scopus citations

Effect of steroids on immunoglobulin-induced eosinophil degranulation

Kita, H., Abu-Ghazaleh, R., Sanderson, C. J. & Gleich, G. J., Jan 1991, In : The Journal of Allergy and Clinical Immunology. 87, 1 PART 1, p. 70-77 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Efficacy of CD4/CD8 ratio of peripheral lymphocytes as a prognostic factor in severely handicapped people with mental retardation

Higashigawa, M., Kamiya, T., Nakano, C., Kubo, M., Kawasaki, H., Higuchi, K., Kita, H., Ihara, T., Kamiya, H. & Sakurai, M., 1991, In : Japanese Journal of National Medical Services. 45, 7, p. 651-655 5 p.

Research output: Contribution to journalArticle

Eosinophil differentiation of human umbilical cord mononuclear cells and prolonged survival of mature eosinophils by murine EL-4 thymoma cell conditioned medium

Ten, R. M., Butterfield, J. H., Kita, H., Weiler, D. A., Fischkoff, S., Ishizaka, T., Sanderson, C. J. & Gleich, G. J., Jul 1991, In : Cytokine. 3, 4, p. 350-359 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Glucocorticoids inhibit cytokine-mediated eosinophil survival

Wallen, N., Kita, H., Weiler, D. & Gleich, G. J., Jan 1 1991, In : Journal of Immunology. 147, 10, p. 3490-3495 6 p.

Research output: Contribution to journalArticle

225 Scopus citations

Granulocyte/macrophage colony-stimulating factor and interleukin 3 release from human peripheral blood eosinophils and neutrophils

Kita, H., Ohnishi, T., Okubo, Y., Weiler, D., Abrams, J. S. & Gleich, G. J., Sep 1 1991, In : Journal of Experimental Medicine. 174, 3, p. 745-748 4 p.

Research output: Contribution to journalArticle

Open Access
256 Scopus citations

Immediate and late airway response of allergic rhinitis patients to segmental antigen challenge: Characterization of eosinophil and mast cell mediators

Sedgwick, J. B., Calhoun, W. J., Gleich, G. J., Kita, H., Abrams, J. S., Schwartz, L. B., Volovitz, B., Ben-Yaakov, M. & Busse, W. W., Jan 1 1991, In : American Review of Respiratory Disease. 144, 6, p. 1274-1281 8 p.

Research output: Contribution to journalArticle

249 Scopus citations

Regulation of Ig-induced eosinophil degranulation by adenosine 3',5'-cyclic monophosphate

Kita, H., Abu-Ghazaleh, R. I., Gleich, G. J. & Abraham, R. T., Jan 1 1991, In : Journal of Immunology. 146, 8, p. 2712-2718 7 p.

Research output: Contribution to journalArticle

114 Scopus citations

Role of pertussis toxin-sensitive G proteins in stimulus-dependent human eosinophil degranulation

Kita, H., Abu-Ghazaleh, R. I., Gleich, G. J. & Abraham, R. T., Jan 1 1991, In : Journal of Immunology. 147, 10, p. 3466-3473 8 p.

Research output: Contribution to journalArticle

44 Scopus citations
1992

Eosinophil granule proteins in peripheral blood granulocytes

Abu-Ghazaleh, R. I., Dunnette, S. L., Loegering, D. A., Checkel, J. L., Kita, H., Thomas, L. L. & Gleich, G. J., Jan 1 1992, In : Journal of Leukocyte Biology. 52, 6, p. 611-618 8 p.

Research output: Contribution to journalArticle

148 Scopus citations

Release of granule proteins from eosinophils cultured with IL-5

Kita, H., Weiler, D. A., Abu-Ghazaleh, R., Sanderson, C. J. & Gleich, G. J., Jan 1 1992, In : Journal of Immunology. 149, 2, p. 629-635 7 p.

Research output: Contribution to journalArticle

124 Scopus citations

The effect of T-cell depletion on enhanced basophil histamine release after in vitro incubation with live influenza A virus.

Huftel, M. A., Swensen, C. A., Borcherding, W. R., Dick, E. C., Hong, R., Kita, H., Gleich, G. J. & Busse, W. W., Oct 1992, In : American journal of respiratory cell and molecular biology. 7, 4, p. 434-440 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
1993

Highlights of the 48th Annual Meeting of the American Academy of Allergy and Immunology

Gleich, G. J., Butterfield, J. H., Leiferman, K. M., Kita, H. & Abrams, J., Jan 1 1993, In : Immunology and Allergy Practice. 15, 1, p. 15-21 7 p.

Research output: Contribution to journalArticle

IL-5 is the predominant eosinophil-active cytokine in the antigen-induced pulmonary late-phase reaction

Ohnishi, T., Kita, H., Weiler, D., Sur, S., Sedgwick, J. B., Calhoun, W. J., Busse, W. W., Abrams, J. S. & Gleich, G. J., 1993, In : American Review of Respiratory Disease. 147, 4, p. 901-907 7 p.

Research output: Contribution to journalArticle

181 Scopus citations

Low R-wave amplitude in the right precordial leads in children with symptomatic doxorubicin cardiomyopathy

Umemoto, M., Azuma, E., Itoh, M., Komada, Y., Ido, M., Kawasaki, H., Kita, H. & Sakurai, M., Mar 1 1993, In : Pediatric Cardiology. 14, 2, p. 107-109 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
1994

Ammonium chloride exposure inhibits cytokine-mediated eosinophil survival

Ide, M., Weiler, D., Kita, H. & Gleich, G. J., Feb 10 1994, In : Journal of Immunological Methods. 168, 2, p. 187-196 10 p.

Research output: Contribution to journalArticle

72 Scopus citations
184 Scopus citations

Endotoxin contamination causes neutrophilia following pulmonary allergen challenge

Hunt, L. W., Gleich, G. J., Ohnishi, T., Weiler, D. A., Mansfield, E. S., Kita, H. & Sur, S., Jun 1994, In : American journal of respiratory and critical care medicine. 149, 6, p. 1471-1475 5 p.

Research output: Contribution to journalArticle

78 Scopus citations

Tyrosine phosphorylation and inositol phosphate production: Are early events in human eosinophil activation stimulated by immobilized secretory IgA and IgG?

Kita, H., Kato, M., Gleich, G. J. & Abraham, R. T., Dec 1994, In : The Journal of Allergy and Clinical Immunology. 94, 6 PART 2, p. 1272-1281 10 p.

Research output: Contribution to journalArticle

18 Scopus citations
1995

A crucial role for β2 integrin in the activation of eosinophils stimulated by IgG

Kaneko, M., Horie, S., Kato, M., Gleich, G. J. & Kita, H., Jan 1 1995, In : Journal of Immunology. 155, 5, p. 2631-2641 11 p.

Research output: Contribution to journalArticle

81 Scopus citations

Allergen-specific IgG1 and IgG3 through FcγRII induce eosinophil degranulation

Kaneko, M., Swanson, M. C., Gleich, G. J. & Kita, H., Jun 1995, In : Journal of Clinical Investigation. 95, 6, p. 2813-2821 9 p.

Research output: Contribution to journalArticle

Open Access
102 Scopus citations

Eosinophil-active cytokine from mononuclear cells cultured with L-tryptophan products: An unexpected consequence of endotoxin contamination

Kita, H., Mayeno, A. N., Weyand, C. M., Goronzy, J. J., Weiler, D. A., Lundy, S. K., Abrams, J. S. & Gleich, G. J., Jun 1995, In : The Journal of Allergy and Clinical Immunology. 95, 6, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Eosinophil adhesion to vascular cell adhesion molecule-1 activates superoxide anion generation

Nagata, M., Sedgwick, J. B., Bates, M. E., Kita, H. & Busse, W. W., Jan 1 1995, In : Journal of Immunology. 155, 4, p. 2194-2202 9 p.

Research output: Contribution to journalArticle

108 Scopus citations

Eosinophil major basic protein induces degranulation and IL-8 production by human eosinophils

Kita, H., Abu-Ghazaleh, R. I., Sur, S. & Gleich, G. J., Jan 1 1995, In : Journal of Immunology. 154, 9, p. 4749-4758 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

Tyrosine phosphorylation is required for eosinophil degranulation induced by immobilized immunoglobulins

Kato, M., Abraham, R. T. & Kita, H., Jan 1 1995, In : Journal of Immunology. 155, 1, p. 357-366 10 p.

Research output: Contribution to journalArticle

34 Scopus citations
1996

Constitutive production of IL-4 and IL-10 and stimulated production of IL-8 by normal peripheral blood eosinophils

Nakajima, H., Gleich, G. J. & Kita, H., Jun 15 1996, In : Journal of Immunology. 156, 12, p. 4859-4866 8 p.

Research output: Contribution to journalArticle

134 Scopus citations

Cytokine production at the site of disease in chronic eosinophilic pneumonitis

Kita, H., Sur, S., Hunt, L. W., Edell, E. S., Weiler, D. A., Swanson, M. C., Samsel, R. W., Abrams, J. S. & Gleich, G. J., Jan 1 1996, In : American journal of respiratory and critical care medicine. 153, 4, p. 1437-1441 5 p.

Research output: Contribution to journalArticle

35 Scopus citations

Cytokines directly induce degranulation and superoxide production from human eosinophils

Horie, S., Gleich, G. J. & Kita, H., Jan 1 1996, In : Journal of Allergy and Clinical Immunology. 98, 2, p. 371-381 11 p.

Research output: Contribution to journalArticle

125 Scopus citations

Elevations in granulocyte-macrophage colony-stimulating factor and interleukin-5 levels precede posttreatment eosinophilia in onchocerciasis

Hagan, J. B., Bartemes, K. R., Kita, H., Ottesen, E. A., Awadzi, K., Nutman, T. B. & Gleich, G. J., Jan 1 1996, In : Journal of Infectious Diseases. 173, 5, p. 1277-1280 4 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Eosinophil recruitment is associated with IL-5, but not with RANTES, twenty-four hours after allergen challenge

Sur, S., Kita, H., Gleich, G. J., Chenier, T. C. & Hunt, L. W., 1996, In : Journal of Allergy and Clinical Immunology. 97, 6, p. 1272-1278 7 p.

Research output: Contribution to journalArticle

58 Scopus citations

Eosinophils in allergy: Role in disease, degranulation, and cytokines

Martin, L. B., Kita, H., Leiferman, K. M. & Gleich, G. J., Jan 1 1996, In : International archives of allergy and immunology. 109, 3, p. 207-215 9 p.

Research output: Contribution to journalArticle

151 Scopus citations

Eosinophil viability during immunoglobulin-induced degranulation

Weiler, C. R., Kita, H., Hukee, M. & Gleich, G. J., Oct 1996, In : Journal of Leukocyte Biology. 60, 4, p. 493-501 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Extracellular matrix proteins attenuate activation and degranulation of stimulated eosinophils

Kita, H., Horie, S. & Gleich, G. J., Feb 1 1996, In : Journal of Immunology. 156, 3, p. 1174-1181 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Lidocaine in bronchoalveolar lavage fluid (BALF) is an inhibitor of eosinophil-active cytokines

Ohnishi, T., Kita, H., Mayeno, A. N., Okada, S., Sur, S., Broide, D. H. & Gleich, G. J., Jan 1 1996, In : Clinical and Experimental Immunology. 104, 2, p. 325-331 7 p.

Research output: Contribution to journalArticle

34 Scopus citations
1997

Migration of Eosinophils through Basement Membrane Components in Vitro: Role of Matrix Metalloproteinase-9

Okada, S., Kita, H., George, T. J., Gleich, G. J. & Leiferman, K. M., Jan 1 1997, In : American journal of respiratory cell and molecular biology. 17, 4, p. 519-528 10 p.

Research output: Contribution to journalArticle

228 Scopus citations

Production of IL-8 and Release of Eosinophil-Derived Neurotoxin by Normal Peripheral Blood Eosinophils

Nakajima, H., Gleich, G. J., Fukuda, T., Makino, S. & Kita, H., Jan 1 1997, In : International archives of allergy and immunology. 114, 1, p. 36-39 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Role of Tyrosine Kinases in Human Eosinophil Degranulation

Kato, M., Kita, H. & Morikawa, A., Jan 1 1997, In : International archives of allergy and immunology. 114, 1, p. 14-17 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Roles of CD9 Molecules in Survival and Activation of Human Eosinophils

Kim, J. T., Gleich, G. J. & Kita, H., Jul 15 1997, In : Journal of Immunology. 159, 2, p. 926-933 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Sulochrin inhibits eosinophil degranulation

Ohashi, H., Ishikawa, M., Ito, J., Ueno, A., Gleich, G. J., Kita, H., Kawai, H. & Fukamachi, H., Nov 1997, In : Journal of Antibiotics. 50, 11, p. 972-974 3 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Transmigration of Eosinophils Through Basement Membrane Components in Vitro: Synergistic Effects of Platelet-activating Factor and Eosinophil-active Cytokines

Okada, S., Kita, H., George, T. J., Gleich, G. J. & Leiferman, K. M., Jan 1 1997, In : American journal of respiratory cell and molecular biology. 16, 4, p. 455-463 9 p.

Research output: Contribution to journalArticle

66 Scopus citations
1998

Cross-linking of the β2 integrin, CD11b/CD18, on human eosinophils induces protein tyrosine phosphorylation and cellular degranulation

Kato, M., Kita, H., Tokuyama, K. & Morikwa, A., Sep 1998, In : International archives of allergy and immunology. 117, SUPPL. 1, p. 68-71 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Eosinophilia and gastrointestinal symptoms after ingestion of shiitake mushrooms

Levy, A. M., Kita, H., Phillips, S. F., Schkade, P. A., Dyer, P. D., Gleich, G. J. & Dubravec, V. A., Jan 1 1998, In : Journal of Allergy and Clinical Immunology. 101, 5, p. 613-620 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Granulocyte macrophage colony-stimulating factor augments ICAM-1 and VCAM-1 activation of eosinophil function

Nagata, M., Sedgwick, J. B., Kita, H. & Busse, W. W., Jan 1 1998, In : American journal of respiratory cell and molecular biology. 19, 1, p. 158-166 9 p.

Research output: Contribution to journalArticle

66 Scopus citations

Inhibition of interleukin-5 mediated eosinophil viability by fluticasone 17-propionate: Comparison with other glucocorticoids

Hagan, J. B., Kita, H. & Gleich, G. J., Sep 9 1998, In : Clinical and Experimental Allergy. 28, 8, p. 999-1006 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Interaction with secretory component stimulates effector functions of human eosinophils but not of neutrophils

Motegi, Y. & Kita, H., Oct 15 1998, In : Journal of Immunology. 161, 8, p. 4340-4346 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Lidocaine and its analogues inhibit IL-5-mediated survival and activation of human eosinophils

Okada, S., Hagan, J. B., Kato, M., Bankers-Fulbright, J. L., Hunt, L. W., Gleich, G. J. & Kita, H., Apr 15 1998, In : Journal of Immunology. 160, 8, p. 4010-4017 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Ligation of the β2 integrin triggers activation and degranulation of human eosinophils

Kato, M., Abraham, R. T., Okada, S. & Kita, H., Jan 1 1998, In : American journal of respiratory cell and molecular biology. 18, 5, p. 675-686 12 p.

Research output: Contribution to journalArticle

65 Scopus citations

Localization of eosinophil-derived neurotoxin and eosinophil cationic protein in neutrophilic leukocytes

Sur, S., Glitz, D. G., Kita, H., Kujawa, S. M., Peterson, E. A., Weiler, D. A., Kephart, G. M., Wagner, J. M., George, T. J., Gleich, G. J. & Leiferman, K. M., Jun 1998, In : Journal of Leukocyte Biology. 63, 6, p. 715-722 8 p.

Research output: Contribution to journalArticle

113 Scopus citations