Hirohito Kita, MD

  • 13400 E Shea Blvd, Mayo Clinic Arizona, MCCRB Room 2-213

    85259 Scottsdale

    United States

  • 14013 Citations
  • 66 Scopus h-Index
1984 …2019
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Research Output 1990 2019

  • 14013 Citations
  • 66 Scopus h-Index
  • 260 Article
  • 4 Chapter
  • 4 Review article
  • 1 Letter
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Article
2019
1 Citation (Scopus)

BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection

Zhu, B., Zhang, R., Li, C., Jiang, L., Xiang, M., Ye, Z., Kita, H., Melnick, A. M., Dent, A. L. & Sun, J., Jun 11 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 24, p. 11888-11893 6 p.

Research output: Contribution to journalArticle

Tissue Survival
Virus Diseases
Orthomyxoviridae
Pneumonia
Neutrophils

Early life represents a vulnerable time window for IL-33–induced peripheral lung pathology

Drake, L. Y., Squillace, D., Iijima, K., Kobayashi, T., Uchida, M., Kephart, G. M., Britt, R., O’Brien, D. R. & Kita, H., Oct 1 2019, In : Journal of Immunology. 203, 7, p. 1952-1960 9 p.

Research output: Contribution to journalArticle

Pathology
Lung
Transgenic Mice
Interleukin-33
Cytokines

Eosinophil peroxidase, GATA3, and T-bet as tissue biomarkers in chronic rhinosinusitis

Lal, D., Wright, B., Shim, K. P., Zarka, M. A., Lee, J. J., Chang, Y. H., Ochkur, S. I., Divekar, R., Doyle, A. D., Jacobsen, E., Kita, H. & Rank, M. A., Jan 1 2019, In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Eosinophil Peroxidase
Biomarkers

Variation in Endoscopic Activity Assessment and Endoscopy Score Validation in Adults With Eosinophilic Esophagitis

International EEsAI Study Group, Jul 1 2019, In : Clinical Gastroenterology and Hepatology. 17, 8, p. 1477-1488.e10

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Endoscopy
Placebos
Exudates and Transudates
Linear Models
2018
10 Citations (Scopus)

Airway exposure initiates peanut allergy by involving the IL-1 pathway and T follicular helper cells in mice

Dolence, J. J., Kobayashi, T., Iijima, K., Krempski, J., Drake, L. Y., Dent, A. L. & Kita, H., Jan 1 2018, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Peanut Hypersensitivity
Helper-Inducer T-Lymphocytes
Interleukin-1
Immunoglobulin E
Flour
7 Citations (Scopus)

Automated chart review utilizing natural language processing algorithm for asthma predictive index

Kaur, H., Sohn, S., Wi, C. I., Ryu, E., Park, M., Bachman, K., Kita, H., Croghan, I. T., Castro-Rodriguez, J. A., Voge, G. A., Liu, H. D. & Juhn, Y. J., Feb 13 2018, In : BMC Pulmonary Medicine. 18, 1, 34.

Research output: Contribution to journalArticle

Natural Language Processing
Asthma
Electronic Health Records
5 Citations (Scopus)

Baseline gastrointestinal eosinophilia is common in oral immunotherapy subjects with IgE-mediated peanut allergy

Wright, B., Fernandez-Becker, N. Q., Kambham, N., Purington, N., Tupa, D., Zhang, W., Rank, M. A., Kita, H., Shim, K. P., Bunning, B. J., Doyle, A. D., Jacobsen, E., Boyd, S. D., Tsai, M., Maecker, H., Manohar, M., Galli, S. J., Nadeau, K. C. & Chinthrajah, R. S., Nov 22 2018, In : Frontiers in Immunology. 9, NOV, 02624.

Research output: Contribution to journalArticle

Peanut Hypersensitivity
Eosinophilia
Eosinophils
Immunotherapy
Immunoglobulin E

Eosinophilic Inflammation in Peritoneal Fibrosis Patients Undergoing Peritoneal Dialysis

Kobayashi, T., Noguchi, T., Saito, K., Shirasaki, F., Kita, H., Nagata, M., Okada, H. & Nakamoto, H., Jan 1 2018, In : Contributions to Nephrology. 196, p. 1-4 4 p.

Research output: Contribution to journalArticle

Peritoneal Fibrosis
Peritoneal Dialysis
Dialysis
Inflammation
Renal Replacement Therapy
26 Citations (Scopus)

IL-33-responsive group 2 innate lymphoid cells are regulated by female sex hormones in the uterus

Bartemes, K., Chen, C. C., Iijima, K., Drake, L. & Kita, H., Jan 1 2018, In : Journal of Immunology. 200, 1, p. 229-236 8 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Uterus
Estrogen Receptors
Lymphocytes
Lung
1 Citation (Scopus)

Innate Immunity Induced by the Major Allergen Alt a 1 From the Fungus Alternaria Is Dependent Upon Toll-Like Receptors 2/4 in Human Lung Epithelial Cells

Hayes, T., Rumore, A., Howard, B., He, X., Luo, M., Wuenschmann, S., Chapman, M., Kale, S., Li, L., Kita, H. & Lawrence, C. B., Jan 1 2018, In : Frontiers in Immunology. 9, 1 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 2
Alternaria
Toll-Like Receptor 4
Innate Immunity
Allergens
9 Citations (Scopus)

Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses

Cheon, I. S., Son, Y. M., Jiang, L., Goplen, N. P., Kaplan, M. H., Limper, A. H., Kita, H., Paczesny, S., Prakash, Y. S., Tepper, R., Ahlfeld, S. K. & Sun, J., Jan 1 2018, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Hyperoxia
Asthma
Premature Infants
Oxidative Stress
Eosinophilia
2017
3 Citations (Scopus)

Airway epithelial anion secretion and barrier function following exposure to fungal aeroallergens: Role of oxidative stress

Zaidman, N. A., O’Grady, K. E., Patil, N., Milavetz, F., Maniak, P. J., Kita, H. & O’Grady, S. M., 2017, In : American Journal of Physiology - Cell Physiology. 313, 1, p. C68-C79

Research output: Contribution to journalArticle

Alternaria
Anions
Oxidative Stress
Mucociliary Clearance
Reactive Oxygen Species
17 Citations (Scopus)

Application of a Natural Language Processing Algorithm to Asthma Ascertainment. An Automated Chart Review

Wi, C. I., Sohn, S., Rolfes, M. C., Seabright, A., Ryu, E., Voge, G., Bachman, K. A., Park, M., Kita, H., Croghan, I. T., Liu, H. D. & Juhn, Y. J., Aug 15 2017, In : American Journal of Respiratory and Critical Care Medicine. 196, 4, p. 430-437 8 p.

Research output: Contribution to journalArticle

Natural Language Processing
Asthma
Electronic Health Records
Cohort Studies
Tracheomalacia
205 Citations (Scopus)

Cellular senescence mediates fibrotic pulmonary disease

Schafer, M. J., White, T. A., Iijima, K., Haak, A. J., Ligresti, G., Atkinson, E. J., Oberg, A. L., Birch, J., Salmonowicz, H., Zhu, Y., Mazula, D. L., Brooks, R. W., Fuhrmann-Stroissnigg, H., Pirtskhalava, T., Prakash, Y. S., Tchkonia, T., Robbins, P. D., Aubry, M. C., Passos, J., Kirkland, J. L. & 3 others, Tschumperlin, D. J., Kita, H. & LeBrasseur, N. K., Feb 23 2017, In : Nature Communications. 8, 14532.

Research output: Contribution to journalArticle

fibrosis
Pulmonary diseases
Cell Aging
Idiopathic Pulmonary Fibrosis
Lung Diseases
1 Citation (Scopus)

Correlation of Symptoms, Clinical Signs, and Biomarkers of Inflammation in Postsurgical Chronic Rhinosinusitis

Racette, S. D., Wijewickrama, R. C., Jayaprakash, V., Sherris, D. A., Santos, C., Kita, H., O'Donnell, F. E. & Ponikau, J. U., Jun 1 2017, In : Annals of Otology, Rhinology and Laryngology. 126, 6, p. 455-462 8 p.

Research output: Contribution to journalArticle

Nose
Signs and Symptoms
Biomarkers
Inflammation
Endoscopy
30 Citations (Scopus)

Follicular helper T cells mediate IgE antibody response to airborne allergens

Kobayashi, T., Iijima, K., Dent, A. L. & Kita, H., Jan 1 2017, In : Journal of Allergy and Clinical Immunology. 139, 1, p. 300-313.e7

Research output: Contribution to journalArticle

Helper-Inducer T-Lymphocytes
Allergens
Immunoglobulin E
Antibody Formation
Cytokines
25 Citations (Scopus)

Oxidative stress serves as a key checkpoint for IL-33 release by airway epithelium

Uchida, M., Anderson, E. L., Squillace, D. L., Patil, N., Maniak, P. J., Iijima, K., Kita, H. & O'Grady, S. M., 2017, (Accepted/In press) In : Allergy: European Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Oxidative Stress
Epithelium
Antioxidants
Alternaria
Esters
2016
8 Citations (Scopus)

Group 2 innate lymphoid cells are increased in nasal polyps in patients with eosinophilic chronic rhinosinusitis

Tojima, I., Kouzaki, H., Shimizu, S., Ogawa, T., Arikata, M., Kita, H. & Shimizu, T., Sep 1 2016, In : Clinical Immunology. 170, p. 1-8 8 p.

Research output: Contribution to journalArticle

Nasal Polyps
Lymphocytes
Nose
Alternaria
Eosinophilia
21 Citations (Scopus)

Group 2 innate lymphoid cells promote an early antibody response to a respiratory antigen in mice

Drake, L. Y., Iijima, K., Bartemes, K. & Kita, H., Aug 15 2016, In : Journal of Immunology. 197, 4, p. 1335-1342 8 p.

Research output: Contribution to journalArticle

Antibody Formation
Lymphocytes
T-Lymphocytes
Immunoglobulin M
Antigens
36 Citations (Scopus)

IL-33 dysregulates regulatory T cells and impairs established immunologic tolerance in the lungs

Chen, C. C., Kobayashi, T., Iijima, K., Hsu, F. C. & Kita, H., Jun 30 2016, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Lung
Antigens
Allergens
GATA3 Transcription Factor
20 Citations (Scopus)

IL-33 mediates reactive eosinophilopoiesis in response to airborne allergen exposure

Anderson, E. L., Kobayashi, T., Iijima, K., Bartemes, K. R., Chen, C. C. & Kita, H., 2016, (Accepted/In press) In : Allergy: European Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Allergens
Interleukin-5
Bone Marrow
Eosinophils
Alternaria
1 Citation (Scopus)

Influence of HLA-DR polymorphism and allergic sensitization on humoral immune responses to intact pneumococcus in a transgenic mouse model

Sheen, Y. H., Rajagopalan, G., Snapper, C. M., Kita, H., Wi, C. I., Umaretiya, P. J. & Juhn, Y. J., Jul 1 2016, In : HLA. 88, 1-2, p. 25-34 10 p.

Research output: Contribution to journalArticle

Pyroglyphidae
HLA-DR Antigens
Humoral Immunity
Streptococcus pneumoniae
Transgenic Mice
11 Citations (Scopus)
Chemokines
Immunoassay
Cytokines
Nasal Polyps
Intercellular Signaling Peptides and Proteins
13 Citations (Scopus)

Urinary Leukotriene E4 to Determine Aspirin Intolerance in Asthma: A Systematic Review and Meta-Analysis

Hagan, J. B., Laidlaw, T. M., Divekar, R., O'Brien, E. K., Kita, H., Volcheck, G. W., Hagan, C. R., Lal, D., Teaford, H. G., Erwin, P. J., Zhang, N. & Rank, M. A., Jun 28 2016, (Accepted/In press) In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

Leukotriene E4
Aspirin
Meta-Analysis
Asthma
Immunoenzyme Techniques
2015
66 Citations (Scopus)

Accuracy, safety, and tolerability of tissue collection by cytosponge vs endoscopy for evaluation of eosinophilic esophagitis

Katzka, D. A., Geno, D. M., Ravi, A., Smyrk, T. C., Lao-Sirieix, P., Miramedi, A., Debiram, I., O'Donovan, M., Kita, H., Kephart, G. M., Kryzer, L. A., Camilleri, M., Alexander, J. A. & Fitzgerald, R. C., Jan 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 1, p. 77-83 7 p.

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Endoscopy
Safety
Eosinophils
Eosinophil-Derived Neurotoxin
5 Citations (Scopus)

Airway responsiveness in CD38-deficient mice in allergic airway disease: Studies with bone marrow chimeras

Guedes, A. G. P., Jude, J. A., Paulin, J., Rivero-Nava, L., Kita, H., Lund, F. E. & Kannan, M. S., 2015, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 308, 5, p. L485-L493

Research output: Contribution to journalArticle

Bone Marrow
Inflammation
Ovalbumin
Allergens
Phenotype

Alternaria inhibits double-stranded RNA-induced cytokines productions through TLR3

Wada, K., Kobayashi, T., Matsuwaki, Y., Moriyama, H. & Kita, H., Jul 1 2015, In : Practica Otologica, Supplement. 143, p. 117-126 10 p.

Research output: Contribution to journalArticle

Alternaria
Double-Stranded RNA
Cytokines
Poly I-C
Virus Diseases
4 Citations (Scopus)

An immunologic test for chronic rhinosinusitis based on free intranasal eosinophilic major basic protein

Ponikau, J. U., Winter, L. A., Kephart, G. M., Squillace, D. L., Hershcovitch, M. D., Moon, S., Sherris, D. A., Kern, E. B., Gleich, G. J. & Kita, H., Jan 1 2015, In : International Forum of Allergy and Rhinology. 5, 1, p. 28-35 8 p.

Research output: Contribution to journalArticle

Immunologic Tests
Mucus
Nose
Proteins
Enzyme-Linked Immunosorbent Assay
12 Citations (Scopus)

ATP drives eosinophil effector responses through P2 purinergic receptors

Kobayashi, T., Soma, T., Noguchi, T., Nakagome, K., Nakamoto, H., Kita, H. & Nagata, M., Sep 1 2015, In : Allergology International. 64, p. S30-S36 71.

Research output: Contribution to journalArticle

Purinergic P2 Receptors
Eosinophils
Adenosine Triphosphate
Uric Acid
Superoxides
11 Citations (Scopus)

B cells play key roles in Th2-type airway immune responses in mice exposed to natural airborne allergens

Drake, L. Y., Iijima, K., Hara, K., Kobayashi, T., Kephart, G. M. & Kita, H., Mar 24 2015, In : PLoS One. 10, 3, e0121660.

Research output: Contribution to journalArticle

allergens
Allergens
B-lymphocytes
B-Lymphocytes
Cells
49 Citations (Scopus)

Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma

Yarova, P. L., Stewart, A. L., Sathish, V., Britt, R. J., Thompson, M. A., P Lowe, A. P., Freeman, M., Aravamudan, B., Kita, H., Brennan, S. C., Schepelmann, M., Davies, T., Yung, S., Cholisoh, Z., Kidd, E. J., Ford, W. R., Broadley, K. J., Rietdorf, K., Chang, W., Bin Khayat, M. E. & 7 others, Ward, D. T., Corrigan, C. J., T Ward, J. P., Kemp, P. J., Pabelick, C. M., Prakash, Y. S. & Riccardi, D., Apr 22 2015, In : Science Translational Medicine. 7, 284

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Asthma
Inflammation
Allergens
Smooth Muscle
13 Citations (Scopus)

Combinatorial immunoprofiling in latent tuberculosis infection: Toward better risk stratification

Escalante, P., Peikert, T. D., Van Keulen, V. P., Erskine, C. L., Bornhorst, C. L., Andrist, B. R., McCoy, K., Pease, L. R., Abraham, R. S., Knutson, K. L., Kita, H., Schrum, A. G. & Limper, A. H., Sep 1 2015, In : American Journal of Respiratory and Critical Care Medicine. 192, 5, p. 605-617 13 p.

Research output: Contribution to journalArticle

Latent Tuberculosis
Immunoassay
Tuberculosis
Phenotype
T-Lymphocytes
19 Citations (Scopus)

Diagnostic Utility of Urinary LTE4 in Asthma, Allergic Rhinitis, Chronic Rhinosinusitis, Nasal Polyps, and Aspirin Sensitivity

Divekar, R., Hagan, J., Rank, M. A., Park, M., Volcheck, G., O'Brien, E., Meeusen, J., Kita, H. & Butterfield, J., Oct 6 2015, (Accepted/In press) In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

Leukotriene E4
Nasal Polyps
Aspirin
Asthma
Allergic Rhinitis
13 Citations (Scopus)

ILC2s and fungal allergy

Kita, H., Jul 1 2015, In : Allergology International. 64, 3, p. 219-226 8 p., 66.

Research output: Contribution to journalArticle

Hypersensitivity
Cytokines
Allergens
Immune System
Fungi
16 Citations (Scopus)

Immunological profiling in chronic rhinosinusitis with nasal polyps reveals distinct VEGF and GM-CSF signatures during symptomatic exacerbations

Divekar, R. D., Samant, S., Rank, M. A., Hagan, J., Lal, D., O'Brien, E. K. & Kita, H., Apr 1 2015, In : Clinical and Experimental Allergy. 45, 4, p. 767-778 12 p.

Research output: Contribution to journalArticle

Nasal Polyps
Granulocyte-Macrophage Colony-Stimulating Factor
Vascular Endothelial Growth Factor A
Nose
Eosinophil Major Basic Protein
92 Citations (Scopus)
Epithelium
Cytokines
Inflammation
Cell Biology
Airway Remodeling
12 Citations (Scopus)

Symptom-Based Clustering in Chronic Rhinosinusitis Relates to History of Aspirin Sensitivity and Postsurgical Outcomes

Divekar, R., Patel, N., Jin, J., Hagan, J., Rank, M. A., Lal, D., Kita, H. & O'Brien, E., Nov 1 2015, In : Journal of Allergy and Clinical Immunology: In Practice. 3, 6, p. 934-940.e3

Research output: Contribution to journalArticle

Aspirin
Cluster Analysis
Symptom Assessment
Demography
Interviews
1 Citation (Scopus)

The FACT score in predicting pneumococcal antibody levels in asthmatics

Podjasek, J. C., Jung, J. A., Kita, H., Park, M. & Juhn, Y. J., May 1 2015, In : Journal of Asthma. 52, 4, p. 370-375 6 p.

Research output: Contribution to journalArticle

Antibodies
Polysaccharides
Pyroglyphidae
Interleukin-5
Humoral Immunity
2014
43 Citations (Scopus)

Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory Mucosa

Hara, K., Iijima, K., Elias, M. K., Seno, S., Tojima, I., Kobayashi, T., Kephart, G. M., Kurabayashi, M. & Kita, H., May 1 2014, In : Journal of Immunology. 192, 9, p. 4032-4042 11 p.

Research output: Contribution to journalArticle

Respiratory Mucosa
Uric Acid
Allergens
Peptide Hydrolases
Asthma
12 Citations (Scopus)

Calcitonin gene-related peptide and vascular endothelial growth factor are expressed in lesional but not uninvolved skin in chronic spontaneous urticaria

Kay, A. B., Ying, S., Ardelean, E., Mlynek, A., Kita, H., Clark, P. & Maurer, M., 2014, In : Clinical and Experimental Allergy. 44, 8, p. 1053-1060 8 p.

Research output: Contribution to journalArticle

Calcitonin Gene-Related Peptide
Urticaria
Vascular Endothelial Growth Factor A
Skin
Blood Vessels
17 Citations (Scopus)

Computed tomography scans as an objective measure of disease severity in chronic rhinosinusitis

Likness, M. M., Pallanch, J. F., Sherris, D. A., Kita, H., Mashtare, T. L. & Ponikau, J. U., Feb 2014, In : Otolaryngology - Head and Neck Surgery (United States). 150, 2, p. 305-311 7 p.

Research output: Contribution to journalArticle

Tomography
Triamcinolone
Intramuscular Injections
Tertiary Care Centers
Multicenter Studies
95 Citations (Scopus)

Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis

Schoepfer, A. M., Straumann, A., Panczak, R., Coslovsky, M., Kuehni, C. E., Maurer, E., Haas, N. A., Romero, Y., Hirano, I., Alexander, J. A., Gonsalves, N., Furuta, G. T., Dellon, E. S., Leung, J., Collins, M. H., Bussmann, C., Netzer, P., Gupta, S. K., Aceves, S. S., Chehade, M. & 46 others, Moawad, F. J., Enders, F. T., Yost, K. J., Taft, T. H., Kern, E., Zwahlen, M., Safroneeva, E., Achem, S. R., Arora, A. S., Alpan, O., Armstrong, D., Attwood, S. E., Butterfield, J. H., Crowell, M. D., De Petris, G., DeVault, K. R., Drouin, E., Enav, B., Fleischer, D. E., Foxx-Orenstein, A., Francis, D. L., Guyatt, G. H., Harris, L. A., Kagalwalla, A. F., Katzka, D. A., Kita, H., Krishna, M., Lee, J. J., Lewis, J. C., Lim, K., Locke, G. R., Murray, J. A., Nguyen, C. C., Orbelo, D. M., Pasha, S. F., Ramirez, F. C., Sheikh, J., Smyrk, T. C., Spergel, J. M., Umar, S. B., Weiler, C. R., Wo, J. M., Woosley, J. T., Wu, T. T., Yan, P. & Yang, G. Y., Dec 1 2014, In : Gastroenterology. 147, 6, p. 1255-1266.e21

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Deglutition Disorders
Validation Studies
Deglutition
Focus Groups
29 Citations (Scopus)

Elevations in vascular markers and eosinophils in chronic spontaneous urticarial weals with low-level persistence in uninvolved skin

Kay, A. B., Ying, S., Ardelean, E., Mlynek, A., Kita, H., Clark, P. & Maurer, M., Sep 1 2014, In : British Journal of Dermatology. 171, 3, p. 505-511 7 p.

Research output: Contribution to journalArticle

Eosinophils
Blood Vessels
Urticaria
Skin
Mast Cells
175 Citations (Scopus)

Enhanced innate type 2 immune response in peripheral blood from patients with asthma

Bartemes, K. R., Kephart, G. M., Fox, S. J. & Kita, H., 2014, In : Journal of Allergy and Clinical Immunology. 134, 3

Research output: Contribution to journalArticle

Innate Immunity
Asthma
Interleukin-13
Interleukin-5
Interleukin-2
79 Citations (Scopus)

Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria

Fujisawa, D., Kashiwakura, J. I., Kita, H., Kikukawa, Y., Fujitani, Y., Sasaki-Sakamoto, T., Kuroda, K., Nunomura, S., Hayama, K., Terui, T., Ra, C. & Okayama, Y., Sep 1 2014, In : The Journal of allergy and clinical immunology. 134, 3, p. 622-633 12 p.

Research output: Contribution to journalArticle

Urticaria
Mast Cells
Skin
Eosinophil Granule Proteins
Substance P
110 Citations (Scopus)

Group 2 innate lymphoid cells and CD4+ T cells cooperate to mediate type 2 immune response in mice

Drake, L. Y., Iijima, K. & Kita, H., 2014, In : Allergy: European Journal of Allergy and Clinical Immunology. 69, 10, p. 1300-1307 8 p.

Research output: Contribution to journalArticle

Lymphocytes
T-Lymphocytes
Cytokines
Adaptive Immunity
Innate Immunity
17 Citations (Scopus)

Group 2 innate lymphoid cells in the lung

Drake, L. Y. & Kita, H., 2014, In : Advances in Immunology. 124, p. 1-16 16 p.

Research output: Contribution to journalArticle

Lymphocytes
Lung
Thromboplastin
Virus Diseases
Innate Immunity
64 Citations (Scopus)

IL-33 and thymic stromal lymphopoietin mediate immune pathology in response to chronic airborne allergen exposure

Iijima, K., Kobayashi, T., Hara, K., Kephart, G. M., Ziegler, S. F., McKenzie, A. N. & Kita, H., Aug 15 2014, In : Journal of Immunology. 193, 4, p. 1549-1559 11 p.

Research output: Contribution to journalArticle

Allergens
Pathology
Adaptive Immunity
Inflammation
Immunoglobulin E
11 Citations (Scopus)

The involvement of glucocorticoids in psychological stress-induced exacerbations of experimental allergic asthma

Okuyama, K., Dobashi, K., Miyasaka, T., Yamazaki, N., Kikuchi, T., Sora, I., Takayanagi, M., Kita, H. & Ohno, I., 2014, In : International Archives of Allergy and Immunology. 163, 4, p. 297-306 10 p.

Research output: Contribution to journalArticle

Psychological Stress
Glucocorticoids
Asthma
Interleukin-13
Antigens
2013
6 Citations (Scopus)

Alternaria inhibits double-stranded RNA-induced cytokine production through Toll-like receptor 3.

Wada, K., Kobayashi, T., Matsuwaki, Y., Moriyama, H. & Kita, H., 2013, In : International Archives of Allergy and Immunology. 161 Suppl 2, p. 75-83 9 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 3
Alternaria
Double-Stranded RNA
Cytokines
Interferons