Haidong M Dong, MD, PhD

  • 13508 Citations
  • 47 Scopus h-Index
1992 …2019
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Research Output 1992 2019

2019

Biomarkers of hyperprogression and pseudoprogression with immune checkpoint inhibitor therapy

Failing, J. J., Dudek, O. A., Marin Acevedo, J. A., Chirila, R. M., Dong, H. M., Markovic, S. N. & Dronca, R. S., Aug 1 2019, In : Future Oncology. 15, 22, p. 2645-2656 12 p.

Research output: Contribution to journalReview article

Biomarkers
Neoplasms
Sample Size
Immunotherapy
Therapeutics

BRAF V600E-induced, tumor intrinsic PD-L1 can regulate chemotherapy-induced apoptosis in human colon cancer cells and in tumor xenografts

Feng, D., Qin, B., Pal, K., Sun, L., Dutta, S., Dong, H., Liu, X., Mukhopadhyay, D., Huang, S. & Sinicrope, F. A., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Heterografts
Colonic Neoplasms
Apoptosis
Ligands
Drug Therapy

Circulating levels of PD-L1 and Galectin-9 are associated with patient survival in surgically treated Hepatocellular Carcinoma independent of their intra-tumoral expression levels

Sideras, K., de Man, R. A., Harrington, S. M., Polak, W. G., Zhou, G., Schutz, H. M., Pedroza-Gonzalez, A., Biermann, K., Mancham, S., Hansen, B. E., Bart Takkenberg, R., van Vuuren, A. J., Pan, Q., Ijzermans, J. N. M., Sleijfer, S., Sprengers, D., Dong, H. M., Kwekkeboom, J. & Bruno, M. J., Dec 1 2019, In : Scientific reports. 9, 1, 10677.

Research output: Contribution to journalArticle

Open Access
Galectins
Hepatocellular Carcinoma
Survival
Liver Transplantation
Biomarkers

Corrigendum to “Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy” [Heliyon 4 (12) (December 2018) e01039] (Heliyon (2018) 4(12), (S2405844018323442), (10.1016/j.heliyon.2018.e01039))

Wu, X., Li, Y., Liu, X., Chen, C., Harrington, S. M., Cao, S., Xie, T., Pham, T., Mansfield, A., Yan, Y., Kwon, E. D., Wang, L. M., Ling, K. & Dong, H. M., Mar 1 2019, In : Heliyon. 5, 3, e01309.

Research output: Contribution to journalComment/debate

Open Access
Drug Therapy
Neoplasms
corrigendum
13 Citations (Scopus)

Neoantigenic Potential of Complex Chromosomal Rearrangements in Mesothelioma

Mansfield, A., Peikert, T. D., Smadbeck, J., Udell, J. B. M., Garcia-Rivera, E., Elsbernd, L., Erskine, C. L., Van Keulen, V. P., Kosari, F., Murphy, S. J., Ren, H., Serla, V. V., Schaefer Klein, J. L., Karagouga, G., Harris, F. R., Sosa, C., Johnson, S. H., Nevala, W., Markovic, S. N., Bungum, A. O. & 6 others, Edell, E., Dong, H. M., Cheville, J., Aubry, M. C., Jen, J. & Vasmatzis, G., Feb 1 2019, In : Journal of Thoracic Oncology. 14, 2, p. 276-287 12 p.

Research output: Contribution to journalArticle

Mesothelioma
T-Lymphocytes
Carcinogens
Atlases
Asbestos

Paradox-driven adventures in the development of cancer immunology and immunotherapy

Barham, W., Gicobi, J. K., Yan, Y., Dronca, R. S. & Dong, H. M., Jan 1 2019, (Accepted/In press) In : Genes and Diseases.

Research output: Contribution to journalReview article

Open Access
Immunology
Allergy and Immunology
Immunotherapy
Social Responsibility
Standard of Care
3 Citations (Scopus)

PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy

Tu, X., Qin, B., Zhang, Y., Zhang, C., Kahila, M., Nowsheen, S., Yin, P., Yuan, J., Pei, H., Li, H., Yu, J., Song, Z., Zhou, Q., Zhao, F., Liu, J., Zhang, C., Dong, H. M., Mutter, R. & Lou, Z., Jun 20 2019, In : Molecular Cell. 74, 6, p. 1215-1226.e4

Research output: Contribution to journalArticle

Exosome Multienzyme Ribonuclease Complex
DNA Damage
Radiation
Drug Therapy
Genetic Therapy
8 Citations (Scopus)

Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression

Jin, X., Ding, D., Yan, Y., Li, H., Wang, B., Ma, L., Ye, Z., Ma, T., Wu, Q., Rodrigues, D. N., Kohli, M., Jimenez, R. E., Wang, L., Goodrich, D. W., de Bono, J., Dong, H. M., Wu, H., Zhu, R. & Huang, H., Jan 3 2019, In : Molecular Cell. 73, 1, p. 22-35.e6

Research output: Contribution to journalArticle

Immunity
E2F Transcription Factors
Neoplasms
Phosphorylation
1 Citation (Scopus)

Prospective Immunophenotyping of CD8+ T Cells and Associated Clinical Outcomes of Patients With Oligometastatic Prostate Cancer Treated With Metastasis-Directed SBRT

Evans, J. D., Morris, L. K., Zhang, H., Cao, S., Liu, X., Mara, K. C., Stish, B. J., Davis, B. J., Mansfield, A., Dronca, R. S., Iott, M. J., Kwon, E. D., Foote, R. L., Olivier, K. R., Dong, H. M. & Park, S. S., Jan 1 2019, In : International Journal of Radiation Oncology Biology Physics. 103, 1, p. 229-240 12 p.

Research output: Contribution to journalArticle

Immunophenotyping
metastasis
Prostatic Neoplasms
cancer
Neoplasm Metastasis
3 Citations (Scopus)

Reverse signaling via PD-L1 supports malignant cell growth and survival in classical Hodgkin lymphoma

Jalali, S., Price-Troska, T., Bothun, C., Villasboas Bisneto, J. J. C. ., Kim, H. J., Yang, Z. Z., Novak, A. J., Dong, H. M. & Ansell, S. M., Mar 1 2019, In : Blood cancer journal. 9, 3, 22.

Research output: Contribution to journalArticle

Hodgkin Disease
Cell Survival
Growth
Ligands
Cell Line
2 Citations (Scopus)

Sex Differences in Tolerability to Anti-Programmed Cell Death Protein 1 Therapy in Patients with Metastatic Melanoma and Non-Small Cell Lung Cancer: Are We All Equal?

Duma, N., Abdel-Ghani, A., Yadav, S., Hoversten, K. P., Reed, C. T., Sitek, A. N., Enninga, E. A. L., Paludo, J., Aguilera, J. V., Leventakos, K., Lou, Y., Kottschade, L. A., Dong, H. M., Mansfield, A., Manochakian, R., Adjei, A. & Dronca, R. S., Jan 1 2019, In : Oncologist.

Research output: Contribution to journalArticle

Programmed Cell Death 1 Receptor
Non-Small Cell Lung Carcinoma
Sex Characteristics
Melanoma
Therapeutics
1 Citation (Scopus)

The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality

Li, C., Zhu, B., Son, Y. M., Wang, Z., Jiang, L., Xiang, M., Ye, Z., Beckermann, K. E., Wu, Y., Jenkins, J. W., Siska, P. J., Vincent, B. G., Prakash, Y. S., Peikert, T., Edelson, B. T., Taneja, R., Kaplan, M. H., Rathmell, J. C., Dong, H., Hitosugi, T. & 1 others, Sun, J., Sep 17 2019, In : Immunity. 51, 3, p. 491-507.e7

Research output: Contribution to journalArticle

Tumor-Infiltrating Lymphocytes
Transcription Factors
T-Lymphocytes
Epigenomics
Immunotherapy
2018
2 Citations (Scopus)

Bim is an independent prognostic marker in intrahepatic cholangiocarcinoma

Zhang, H., Jenkins, S. M., Lee, C. T., Harrington, S. M., Liu, Z., Dong, H. M. & Zhang, L., Aug 1 2018, In : Human Pathology. 78, p. 97-105 9 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Neoplasms
Survival
Lymph Nodes
Immunohistochemistry
26 Citations (Scopus)

Combining Immune Checkpoint Inhibitors With Conventional Cancer Therapy

Yan, Y., Kumar, A. B., Finnes, H., Markovic, S. N., Park, S. S., Dronca, R. S. & Dong, H. M., Jan 1 2018, In : Frontiers in Immunology. 9, 1 p.

Research output: Contribution to journalReview article

Neoplasms
Radiotherapy
Therapeutics
Drug Therapy
Immunomodulation
15 Citations (Scopus)

Contraction of T cell richness in lung cancer brain metastases

Mansfield, A., Ren, H., Sutor, S., Sarangi, V., Nair, A., Davila, J., Elsbernd, L. R., Udell, J. B., Dronca, R. S., Park, S. S., Markovic, S. N., Sun, Z. D., Halling, K. C., Nevala, W. K., Aubry, M. C., Dong, H. M. & Jen, J., Dec 1 2018, In : Scientific Reports. 8, 1, 2171.

Research output: Contribution to journalArticle

Brain Neoplasms
Lung Neoplasms
Clone Cells
Neoplasm Metastasis
T-Lymphocytes
10 Citations (Scopus)

CX3CR1 identifies PD-1 therapy-responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy

Yan, Y., Cao, S., Liu, X., Harrington, S. M., Bindeman, W. E., Adjei, A. A., Jang, J. S., Jen, J., Li, Y., Chanana, P., Mansfield, A. S., Park, S. S., Markovic, S. N., Dronca, R. S. & Dong, H., Apr 19 2018, In : JCI insight. 3, 8

Research output: Contribution to journalArticle

Open Access
T-Lymphocytes
Drug Therapy
Aptitude
Neoplasms
Therapeutics
178 Citations (Scopus)

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

Chen, G., Huang, A. C., Zhang, W., Zhang, G., Wu, M., Xu, W., Yu, Z., Yang, J., Wang, B., Sun, H., Xia, H., Man, Q., Zhong, W., Antelo, L. F., Wu, B., Xiong, X., Liu, X., Guan, L., Li, T., Liu, S. & 19 others, Yang, R., Lu, Y., Dong, L., McGettigan, S., Somasundaram, R., Radhakrishnan, R., Mills, G., Lu, Y., Kim, J., Chen, Y. H., Dong, H. M., Zhao, Y., Karakousis, G. C., Mitchell, T. C., Schuchter, L. M., Herlyn, M., Wherry, E. J., Xu, X. & Guo, W., Aug 16 2018, In : Nature. 560, 7718, p. 382-386 5 p.

Research output: Contribution to journalLetter

Immunosuppression
Ligands
Neoplasms
T-Lymphocytes
Interferons
2 Citations (Scopus)
Paclitaxel
Adenocarcinoma
Programmed Cell Death 1 Receptor
Drug Therapy
Esophagogastric Junction
77 Citations (Scopus)

PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

Tang, H., Liang, Y., Anders, R. A., Taube, J. M., Qiu, X., Mulgaonkar, A., Liu, X., Harrington, S. M., Guo, J., Xin, Y., Xiong, Y., Nham, K., Silvers, W., Hao, G., Sun, X., Chen, M., Hannan, R., Qiao, J., Dong, H. M., Peng, H. & 1 others, Fu, Y. X., Feb 1 2018, In : Journal of Clinical Investigation. 128, 2, p. 580-588 9 p.

Research output: Contribution to journalArticle

Neoplasms
Antigen-Presenting Cells
T-Lymphocytes
Therapeutics
Myeloid Cells
7 Citations (Scopus)

Prevalent homozygous deletions of type i interferon and defensin genes in human cancers associate with immunotherapy resistance

Ye, Z., Dong, H. M., Li, Y., Ma, T., Huang, H., Leong, H. S., Eckel-Passow, J. E., Kocher, J-P., Liang, H. & Wang, L., Jul 15 2018, In : Clinical Cancer Research. 24, 14, p. 3299-3308 10 p.

Research output: Contribution to journalArticle

Defensins
Immunotherapy
Interferons
Genes
Neoplasms
2 Citations (Scopus)

Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy

Wu, X., Li, Y., Liu, X., Chen, C., Harrington, S. M., Cao, S., Xie, T., Orzechowski, A., Pham, T., Mansfield, A., Yan, Y., Kwon, E. D., Wang, L. M., Ling, K. & Dong, H. M., Dec 1 2018, In : Heliyon. 4, 12, e01039.

Research output: Contribution to journalArticle

Drug Therapy
Neoplasms
p38 Mitogen-Activated Protein Kinases
Clustered Regularly Interspaced Short Palindromic Repeats
B7 Antigens
5 Citations (Scopus)

Targeting IFNα to tumor by anti-PD-L1 creates feedforward antitumor responses to overcome checkpoint blockade resistance

Liang, Y., Tang, H., Guo, J., Qiu, X., Yang, Z., Ren, Z., Sun, Z., Bian, Y., Xu, L., Xu, H., Shen, J., Han, Y., Dong, H. M., Peng, H. & Fu, Y. X., Dec 1 2018, In : Nature Communications. 9, 1, 4586.

Research output: Contribution to journalArticle

interferon
Interferons
Tumors
tumors
T-cells
1 Citation (Scopus)

The basic concepts in cancer immunology and immunotherapy

Dong, H. M., Jan 5 2018, The Basics of Cancer Immunotherapy. Springer International Publishing, p. 1-19 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Allergy and Immunology
Immunotherapy
Neoplasms

The basics of cancer immunotherapy

Dong, H. M. & Markovic, S. N., Jan 5 2018, Springer International Publishing. 160 p.

Research output: Book/ReportBook

Immunotherapy
Neoplasms
Physicians
Health Personnel
Immune System
2017
71 Citations (Scopus)

Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas

Zhou, G., Sprengers, D., Boor, P. P. C., Doukas, M., Schutz, H., Mancham, S., Pedroza-Gonzalez, A., Polak, W. G., de Jonge, J., Gaspersz, M., Dong, H. M., Thielemans, K., Pan, Q., IJzermans, J. N. M., Bruno, M. J. & Kwekkeboom, J., Oct 1 2017, In : Gastroenterology. 153, 4, p. 1107-1119.e10

Research output: Contribution to journalArticle

Tumor-Infiltrating Lymphocytes
Hepatocellular Carcinoma
Lymphocytes
T-Lymphocytes
Antibodies
11 Citations (Scopus)

B7-H1 influences the accumulation of virus-specific tissue resident memory T cells in the central nervous system

Pavelko, K. D., Bell, M. P., Harrington, S. M. & Dong, H. M., Nov 9 2017, In : Frontiers in Immunology. 8, NOV, 1532.

Research output: Contribution to journalArticle

Central Nervous System
Viruses
T-Lymphocytes
Theilovirus
Nerve Tissue
26 Citations (Scopus)

Functional expression of programmed death-ligand 1 (B7-H1) by immune cells and tumor cells

Johnson, R. M. G. & Dong, H. M., Aug 10 2017, In : Frontiers in Immunology. 8, AUG, 961.

Research output: Contribution to journalReview article

CD80 Antigens
T-Lymphocytes
Neoplasms
Antibodies
Therapeutics
13 Citations (Scopus)

Immune checkpoint molecules soluble program death ligand 1 and galectin-9 are increased in pregnancy

Enninga, E. A. L., Harrington, S. M., Creedon, D. J., Ruano, R., Markovic, S. N., Dong, H. M. & Dronca, R. S., Jan 1 2017, (Accepted/In press) In : American Journal of Reproductive Immunology.

Research output: Contribution to journalArticle

Galectin 1
Galectins
Ligands
Pregnancy
Fetus
26 Citations (Scopus)

PD-L1 interacts with CD80 to regulate graft-versusleukemia activity of donor CD8+ T cells

Ni, X., Song, Q., Cassady, K., Deng, R., Jin, H., Zhang, M., Dong, H. M., Forman, S., Martin, P. J., Chen, Y. Z., Wang, J. & Zeng, D., May 1 2017, In : Journal of Clinical Investigation. 127, 5, p. 1960-1977 18 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Ligands
T-Lymphocytes
Transplants
Leukemia
94 Citations (Scopus)

Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL

Ding, W. D., LaPlant, B. R., Call, T. G., Parikh, S. A., Leis, J. F., He, R., Shanafelt, T. D., Sinha, S., Le-Rademacher, J., Feldman, A. L., Habermann, T. M., Witzig, T. E., Wiseman, G. A., Lin, Y., Asmus, E., Nowakowski, G. S., Conte, M. J., Bowen, D. A., Aitken, C. N., Van Dyke, D. L. & 15 others, Greipp, P. T., Liu, X., Wu, X., Zhang, H., Secreto, C. R., Tian, S., Braggio, E. D., Wellik, L. E., Micallef, I., Viswanatha, D. S., Yan, H. D., Chanan Khan, A. A., Kay, N. E., Dong, H. M. & Ansell, S. M., Jun 29 2017, In : Blood. 129, 26, p. 3419-3427 9 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Tumors
Blocking Antibodies
Ligands
pembrolizumab
11 Citations (Scopus)

Temporal and spatial heterogeneity of programmed cell death 1-Ligand 1 expression in malignant mesothelioma

Terra, S. B. S. P., Mansfield, A., Dong, H. M., Peikert, T. D. & Roden, A., Aug 19 2017, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

CD274 Antigen
Pemetrexed
Mesothelioma
Malignant Mesothelioma
Clone Cells
8 Citations (Scopus)

Type Iγ phosphatidylinositol phosphate kinase regulates PD-L1 expression by activating NF-κB

Xue, J., Chen, C., Qi, M., Huang, Y., Wang, L., Gao, Y., Dong, H. M. & Ling, K., 2017, In : Oncotarget. 8, 26, p. 42414-42427 14 p.

Research output: Contribution to journalArticle

Phosphatidylinositol Phosphates
Phosphotransferases
Ligands
Triple Negative Breast Neoplasms
Neoplasms
2 Citations (Scopus)

Undifferentiated Pancreatic Carcinomas Display Enrichment for Frequency and Extent of PD-L1 Expression by Tumor Cells

Lehrke, H. D., Graham, R., Mc Williams, R. R., Lam-Himlin, D. M., Smyrk, T. C., Jenkins, S., Dong, H. M. & Zhang, L., Nov 2 2017, In : American Journal of Clinical Pathology. 148, 5, p. 441-449 9 p.

Research output: Contribution to journalArticle

Ligands
Carcinoma
Neoplasms
Adenocarcinoma
Pancreatic Carcinoma
2016
10 Citations (Scopus)

B7-H1 antibodies lose antitumor activity due to activation of p38 MAPK that leads to apoptosis of tumor-reactive CD8+T cells

Liu, X., Wu, X., Cao, S., Harrington, S. M., Yin, P., Mansfield, A. & Dong, H. M., Nov 8 2016, In : Scientific Reports. 6, 36722.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Apoptosis
T-Lymphocytes
Antibodies
Neoplasms
4 Citations (Scopus)
Immunotherapy
Melanoma
Cell Death
Biomarkers
T-Lymphocytes
13 Citations (Scopus)

CpG-induced antitumor immunity requires IL-12 in expansion of effector cells and down-regulation of PD-1

Yin, P., Liu, X., Mansfield, A., Harrington, S. M., Li, Y., Yan, Y. & Dong, H. M., 2016, In : Oncotarget. 7, 43, p. 70223-70231 9 p.

Research output: Contribution to journalArticle

Interleukin-12
Immunity
Down-Regulation
T-Lymphocytes
Toll-Like Receptor 9
15 Citations (Scopus)
CD274 Antigen
Non-Small Cell Lung Carcinoma
Immunotherapy
Patient Selection
Cell Death
19 Citations (Scopus)

PD-1 blunts the function of ovarian tumor-infiltrating dendritic cells by inactivating NF-κB

Karyampudi, L., Lamichhane, P., Krempski, J., Kalli, K. R., Behrens, M. D., Vargas, D. M., Hartmann, L. C., Janco, J. M. T., Dong, H. M., Hedin, K. E., Dietz, A. B., Goode, E. L. & Knutson, K. L., Jan 15 2016, In : Cancer Research. 76, 2, p. 239-250 12 p.

Research output: Contribution to journalArticle

Dendritic Cells
Neoplasms
Lymphocytes
Antigen Presentation
Myeloid Cells
3 Citations (Scopus)
Prostatic Neoplasms
Lymph Nodes
T-Lymphocytes
Neoplasms
Immunosuppressive Agents
108 Citations (Scopus)
Lung Neoplasms
Cell Death
Tumor-Infiltrating Lymphocytes
Tumor Microenvironment
Lymphocytes
2015
6 Citations (Scopus)

A gender factor in shaping T-cell immunity to melanoma

Dronca, R. S. & Dong, H. M., 2015, In : Frontiers in Oncology. 5, FEB, 8.

Research output: Contribution to journalArticle

Immunity
Melanoma
T-Lymphocytes
7 Citations (Scopus)

Immunomodulatory antibody therapy of Cancer: The closer, the better

Dronca, R. S. & Dong, H. M., Mar 1 2015, In : Clinical Cancer Research. 21, 5, p. 944-946 3 p.

Research output: Contribution to journalArticle

Immunomodulation
Antibodies
Neoplasms
Therapeutic Uses
Therapeutics
5 Citations (Scopus)

Immunotherapy in Prostate Cancer

Sobol, I., Thompson, R. H., Dong, H. M., Krco, C. & Kwon, E. D., Jun 1 2015, In : Current Urology Reports. 16, 6, p. 1-5 5 p.

Research output: Contribution to journalArticle

docetaxel
Immunotherapy
Prostatic Neoplasms
Survival
Prostate
147 Citations (Scopus)

PD-1 restrains radiotherapy-induced abscopal effect

Park, S. S., Dong, H. M., Liu, X., Harrington, S. M., Krco, C. J., Grams, M. P., Mansfield, A., Furutani, K. M., Olivier, K. R. & Kwon, E. D., Jun 1 2015, In : Cancer immunology research. 3, 6, p. 610-619 10 p.

Research output: Contribution to journalArticle

Radiotherapy
Knockout Mice
Neoplasms
Blocking Antibodies
Renal Cell Carcinoma
16 Citations (Scopus)

Stem cells for murine interstitial cells of Cajal suppress cellular immunity and colitis via prostaglandin E<inf>2</inf> secretion

Dave, M., Hayashi, Y., Gajdos, G. B., Smyrk, T. C., Svingen, P. A., Kvasha, S. M., Lorincz, A., Dong, H. M., Faubion, W. A. & Ordog, T., May 1 2015, In : Gastroenterology. 148, 5, p. 978-990 13 p.

Research output: Contribution to journalArticle

Interstitial Cells of Cajal
Colitis
Dinoprostone
Cellular Immunity
Stem Cells
6 Citations (Scopus)

Synergy of cancer immunotherapy and radiotherapy

Mansfield, A., Park, S. S. & Dong, H. M., 2015, In : Aging. 7, 3, p. 144-145 2 p.

Research output: Contribution to journalArticle

Combined Modality Therapy
Immunotherapy
Radiotherapy
Neoplasms
2014
114 Citations (Scopus)

B7-H1 expression in malignant pleural mesothelioma is associated with sarcomatoid histology and poor prognosis

Mansfield, A., Roden, A., Peikert, T. D., Sheinin, Y. M., Harrington, S. M., Krco, C. J., Dong, H. M. & Kwon, E. D., 2014, In : Journal of Thoracic Oncology. 9, 7, p. 1036-1040 5 p.

Research output: Contribution to journalArticle

Mesothelioma
Histology
Survival
CD274 Antigen
Neoplasms
8 Citations (Scopus)

B7-H1 signaling is integrated during CD8+ T cell priming and restrains effector differentiation

Gibbons, R. M., Liu, X., Harrington, S. M., Krco, C. J., Kwon, E. D. & Dong, H. M., 2014, In : Cancer Immunology, Immunotherapy. 63, 8, p. 859-867 9 p.

Research output: Contribution to journalArticle

Dendritic Cells
T-Lymphocytes
Immunotherapy
Neoplasms
Cancer Vaccines
2013
20 Citations (Scopus)

Endogenous tumor-reactive CD8+ T cells are differentiated effector cells expressing high levels of CD11a and PD-1 but are unable to control tumor growth

Liu, X., Gibbons, R. M., Harrington, S. M., Krco, C. J., Markovic, S. N., Kwon, E. D. & Dong, H. M., Jun 2013, In : OncoImmunology. 2, 6, e23972.

Research output: Contribution to journalArticle

T-Lymphocytes
Growth
Neoplasms
Biomarkers
Cytotoxic T-Lymphocytes
108 Citations (Scopus)

Marrow stromal cells induce B7-H1 expression on myeloma cells, generating aggressive characteristics in multiple myeloma

Tamura, H., Ishibashi, M., Yamashita, T., Tanosaki, S., Okuyama, N., Kondo, A., Hyodo, H., Shinya, E., Takahashi, H., Dong, H. M., Tamada, K., Chen, L., Dan, K. & Ogata, K., Feb 2013, In : Leukemia. 27, 2, p. 464-472 9 p.

Research output: Contribution to journalArticle

Stromal Cells
Multiple Myeloma
Bone Marrow
Cell Line
B7 Antigens