George Vasmatzis, PhD

  • 4428 Citations
  • 39 Scopus h-Index
1993 …2019
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Research Output 1993 2019

  • 4428 Citations
  • 39 Scopus h-Index
  • 123 Article
  • 2 Letter
  • 1 Conference contribution
  • 1 Review article
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Article
2019

A comparison of adult rhabdomyosarcoma and high-grade neuroendocrine carcinoma of the urinary bladder reveals novel PPP1R12A fusions in rhabdomyosarcoma

Gupta, S., Sosa, C. P., Kosari, F., Folpe, A., Bhinge, K. N., Yang, L., Agahi, A., Johnson, S. H., Frank, I., Boorjian, S. A., Hansel, D. E., Al-Ahmadie, H. A., Reuter, V. E., Vasmatzis, G., Jimenez, R. E., Herrera-Hernandez, L. & Cheville, J., Jun 1 2019, In : Human Pathology. 88, p. 48-59 12 p.

Research output: Contribution to journalArticle

Neuroendocrine Carcinoma
Rhabdomyosarcoma
Urinary Bladder
RNA Sequence Analysis
Alveolar Rhabdomyosarcoma
1 Citation (Scopus)

Acute leukemias harboring KMT2A/MLLT10 fusion: a 10-year experience from a single genomics laboratory

Peterson, J. F., Sukov, W. R., Pitel, B. A., Smoley, S. A., Pearce, K. E., Meyer, R. G., Williamson, C. M., Smadbeck, J. B., Vasmatzis, G., Hoppman, N. L., Greipp, P. T., Baughn, L. & Ketterling, R. P., Jan 1 2019, In : Genes Chromosomes and Cancer.

Research output: Contribution to journalArticle

Genomics
Leukemia
Fluorescence In Situ Hybridization
Acute Myeloid Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma

Characterization of a cryptic IGH/CCND1 rearrangement in a case of mantle cell lymphoma with negative CCND1 FISH studies

Peterson, J. F., Baughn, L., Ketterling, R. P., Pitel, B. A., Smoley, S. A., Vasmatzis, G., Smadbeck, J. B., Greipp, P. T., Mangaonkar, A. A., Thompson, C. A., Parikh, S. A., Chen, D. & Viswanatha, D. S., Jan 1 2019, In : Blood Advances. 3, 8, p. 1298-1302 5 p.

Research output: Contribution to journalArticle

Open Access
Mantle-Cell Lymphoma
Cyclin D1
Fluorescence In Situ Hybridization
B-Cell Lymphoma
Cyclin D

Characterization of a rarely reported STAT5B/RARA gene fusion in a young adult with newly diagnosed acute promyelocytic leukemia with resistance to ATRA therapy

Peterson, J. F., He, R. R., Nayer, H., Cuevo, R. S., Smadbeck, J. B., Vasmatzis, G., Greipp, P. T., Ketterling, R. P., Hoppman, N. L. & Baughn, L., Sep 1 2019, In : Cancer Genetics. 237, p. 51-54 4 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Gene Fusion
Tretinoin
Young Adult
Fluorescence In Situ Hybridization

Detection of a cryptic NUP214/ABL1 gene fusion by mate-pair sequencing (MPseq) in a newly diagnosed case of pediatric T-lymphoblastic leukemia

Peterson, J. F., Pitel, B. A., Smoley, S. A., Smadbeck, J. B., Johnson, S. H., Vasmatzis, G., Koon, S. J., Webley, M. R., McGrath, M., Bayerl, M. G., Baughn, L., Rowsey, R. A., Ketterling, R. P., Greipp, P. T. & Hoppman, N. L., Apr 1 2019, In : Cold Spring Harbor molecular case studies. 5, 2

Research output: Contribution to journalArticle

Open Access
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics
T-cells
Gene Fusion
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Open Access
B-Cell Lymphoma
Fluorescence In Situ Hybridization
Non-Hodgkin's Lymphoma
Fluorescence
Cells
1 Citation (Scopus)

Immune Cell Infiltration May Be a Key Determinant of Long-Term Survival in Small Cell Lung Cancer

Muppa, P., Parrilha Terra, S. B. S., Sharma, A., Mansfield, A., Aubry, M. C., Bhinge, K., Asiedu, M. K., De Andrade, M., Janaki, N., Murphy, S. J., Nasir, A., Van Keulen, V., Vasmatzis, G., Wigle, D. A., Yang, P., Yi, E. S., Peikert, T. D. & Kosari, F., Jul 1 2019, In : Journal of Thoracic Oncology. 14, 7, p. 1286-1295 10 p.

Research output: Contribution to journalArticle

Open Access
Small Cell Lung Carcinoma
Tumor Microenvironment
Survival Rate
Survivors
Survival

Large Chromosomal Rearrangements Yield Biomarkers to Distinguish Low-Risk From Intermediate- and High-Risk Prostate Cancer

Vasmatzis, G., Kosari, F., Murphy, S. J., Terra, S., Kovtun, I. V., Harris, F. R., Zarei, S., Smadbeck, J., Johnson, S. H., Gaitatzes, A. G., Therneau, T. M., Rangel, L. J., Knudson, R. A., Greipp, P. T., Sukov, W. R., Knutson, D. L., Kloft-Nelson, S. M., Karnes, R. J. & Cheville, J., Jan 1 2019, In : Mayo Clinic Proceedings. 94, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Biomarkers
Area Under Curve
Neoplasm Grading
Needle Biopsy
5 Citations (Scopus)

Mate pair sequencing improves detection of genomic abnormalities in acute myeloid leukemia

Aypar, U., Smoley, S. A., Pitel, B. A., Pearce, K. E., Zenka, R. M., Vasmatzis, G., Johnson, S. H., Smadbeck, J. B., Peterson, J. F., Geiersbach, K. B., Van Dyke, D. L., Thorland, E. C., Jenkins, R. B., Ketterling, R. P., Greipp, P. T., Kearney, H. M., Hoppman, N. L. & Baughn, L., Jan 1 2019, In : European Journal of Haematology. 102, 1, p. 87-96 10 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Cytogenetics
Hematologic Neoplasms
Fluorescence In Situ Hybridization
Molecular Biology
8 Citations (Scopus)

Neoantigenic Potential of Complex Chromosomal Rearrangements in Mesothelioma

Mansfield, A., Peikert, T. D., Smadbeck, J., Udell, J. B. M., Garcia-Rivera, E., Elsbernd, L., Erskine, C. L., Van Keulen, V. P., Kosari, F., Murphy, S. J., Ren, H., Serla, V. V., Schaefer Klein, J. L., Karagouga, G., Harris, F. R., Sosa, C., Johnson, S. H., Nevala, W., Markovic, S. N., Bungum, A. O. & 6 others, Edell, E., Dong, H. M., Cheville, J., Aubry, M. C., Jen, J. & Vasmatzis, G., Feb 1 2019, In : Journal of Thoracic Oncology. 14, 2, p. 276-287 12 p.

Research output: Contribution to journalArticle

Mesothelioma
T-Lymphocytes
Carcinogens
Atlases
Asbestos

Shared and unique genomic structural variants of different histological components within testicular germ cell tumours identified with mate pair sequencing

Bryce, A. H., Egan, J. B., Smadbeck, J., Johnson, S. H., Murphy, S. J., Harris, F. R., Halling, G. C., Terra, S. B. S. P., Cheville, J., Pagliaro, L., Leibovich, B., Costello, B. & Vasmatzis, G., Dec 1 2019, In : Scientific reports. 9, 1, 3586.

Research output: Contribution to journalArticle

Open Access
Genomic Structural Variation
Exome
Histology
Neoplasms
Protein Isoforms

Use of mate-pair sequencing to characterize a complex cryptic BCR/ABL1 rearrangement observed in a newly diagnosed case of chronic myeloid leukemia

Peterson, J. F., Pitel, B. A., Smoley, S. A., Smadbeck, J. B., Johnson, S. H., Vasmatzis, G., Kearney, H. M., Greipp, P. T., Hoppman, N. L., Baughn, L. & Ketterling, R. P., Jan 1 2019, In : Human Pathology.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 22
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Fluorescence In Situ Hybridization
Cytogenetics
Chromosomes

Using Genomics to Differentiate Multiple Primaries From Metastatic Lung Cancer

Murphy, S. J., Harris, F. R., Kosari, F., Barreto Siqueira Parrilha Terra, S., Nasir, A., Johnson, S. H., Serla, V., Smadbeck, J. B., Halling, G. C., Karagouga, G., Sukov, W. R., Leventakos, K., Yang, P., Peikert, T. D., Mansfield, A., Wigle, D. A., Yi, E. S., Kipp, B. R., Vasmatzis, G. & Aubry, M. C., Jan 1 2019, In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Open Access
Genomics
Lung Neoplasms
Neoplasms
DNA
Histology

Whole Genome Mate-pair Sequencing of Plasma Cell Neoplasm as a Novel Diagnostic Strategy: A Case of Unrecognized t(2;11) Structural Variation

Peterson, J. F., Meyer, R. G., Smoley, S. A., Webley, M., Smadbeck, J. B., Vasmatzis, G., Pearce, K., Greipp, P. T., Ketterling, R. P., Craig, F. E., Stewart, A. K. & Baughn, L., Jan 1 2019, In : Clinical Lymphoma, Myeloma and Leukemia.

Research output: Contribution to journalArticle

Open Access
Plasma Cell Neoplasms
Multiple Myeloma
Fluorescence In Situ Hybridization
Genome
2018

Chromoanasynthesis is a common mechanism that leads to ERBB2 amplifications in a cohort of early stage HER2+ breast cancer samples

Vasmatzis, G., Wang, X., Smadbeck, J. B., Murphy, S. J., Geiersbach, K. B., Johnson, S. H., Gaitatzes, A. G., Asmann, Y., Kosari, F., Borad, M. J., Serie, D. J., McLaughlin, S. A., Kachergus, J. M., Necela, B. M. & Thompson, E. A., Jul 13 2018, In : BMC Cancer. 18, 1, 738.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 8
Breast Neoplasms
Chromosomes, Human, Pair 17
Transcriptome
Genome

Constitutional chromosome rearrangements that mimic the 2017 world health organization “acute myeloid leukemia with recurrent genetic abnormalities”: A study of three cases and review of the literature

Peterson, J. F., Pitel, B. A., Smoley, S. A., Smadbeck, J. B., Johnson, S. H., Vasmatzis, G., Pearce, K. E., He, R., Kelemen, K., Al-Mondhiry, H. A. B., Lamparella, N. E., Hoppman, N. L., Kearney, H. M., Baughn, L., Ketterling, R. P. & Greipp, P. T., Jan 1 2018, (Accepted/In press) In : Cancer genetics.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Chromosomes
Bone Marrow
Primary Ovarian Insufficiency
Hematologic Neoplasms
10 Citations (Scopus)

Copy number variant analysis using genome-wide mate-pair sequencing

Smadbeck, J. B., Johnson, S. H., Smoley, S. A., Gaitatzes, A., Drucker, T. M., Zenka, R. M., Kosari, F., Murphy, S. J., Hoppman, N., Aypar, U., Sukov, W. R., Jenkins, R. B., Kearney, H. M., Feldman, A. L. & Vasmatzis, G., Sep 1 2018, In : Genes Chromosomes and Cancer. 57, 9, p. 459-470 12 p.

Research output: Contribution to journalArticle

Cytogenetic Analysis
Genome
Technology
Karyotyping
Human Genome
4 Citations (Scopus)

Enhanced mRNA FISH with compact quantum dots

Liu, Y., Le, P., Lim, S. J., Ma, L., Sarkar, S., Han, Z., Murphy, S. J., Kosari, F., Vasmatzis, G., Cheville, J. & Smith, A. M., Dec 1 2018, In : Nature Communications. 9, 1, 4461.

Research output: Contribution to journalArticle

Quantum Dots
Fluorescence In Situ Hybridization
Semiconductor quantum dots
Fluorescence
quantum dots
5 Citations (Scopus)

Genome U-Plot: A whole genome visualization

Gaitatzes, A., Johnson, S. H., Smadbeck, J. B. & Vasmatzis, G., May 15 2018, In : Bioinformatics. 34, 10, p. 1629-1634 6 p.

Research output: Contribution to journalArticle

Genome
Visualization
Genes
Spatial Resolution
Layout
4 Citations (Scopus)

Pathways impacted by genomic alterations in pulmonary carcinoid tumors

Asiedu, M. K., Thomas, C. F., Dong, J., Schulte, S. C., Khadka, P., Sun, Z. D., Kosari, F., Jen, J., Molina, J. R., Vasmatzis, G., Kuang, R., Aubry, M. C., Yang, P. & Wigle, D. A., Apr 1 2018, In : Clinical Cancer Research. 24, 7, p. 1691-1704 14 p.

Research output: Contribution to journalArticle

Carcinoid Tumor
Lung
Neoplasm Genes
Biological Phenomena
Exome

Proposal for Modification of Cahan's Criteria Utilizing Molecular Genetic Analyses for Cases without Baseline Histopathology: A Unique Method Applicable to Primary Radiosurgery

Rusheen, A. E., Smadbeck, J. B., Schimmenti, L. A., Klee, E. W., Link, M. J., Vasmatzis, G. & Carlson, M. L., May 31 2018, (Accepted/In press) In : Journal of Neurological Surgery, Part B: Skull Base.

Research output: Contribution to journalArticle

Radiosurgery
Molecular Biology
Sarcoma
Acoustic Neuroma
Radiation
21 Citations (Scopus)

SVAtools for junction detection of genome-wide chromosomal rearrangements by mate-pair sequencing (MPseq)

Johnson, S. H., Smadbeck, J. B., Smoley, S. A., Gaitatzes, A., Murphy, S. J., Harris, F. R., Drucker, T. M., Zenka, R. M., Pitel, B. A., Rowsey, R. A., Hoppman, N. L., Aypar, U., Sukov, W. R., Jenkins, R. B., Feldman, A. L., Kearney, H. M. & Vasmatzis, G., Feb 1 2018, In : Cancer genetics. 221, p. 1-18 18 p.

Research output: Contribution to journalArticle

Karyotype
Genome
Genomic Structural Variation
Karyotyping
Genomic Library
1 Citation (Scopus)

Targeting HER2 in patient-derived xenograft ovarian cancer models sensitizes tumors to chemotherapy

Harris, F. R., Zhang, P., Yang, L., Hou, X., Leventakos, K., Weroha, S. J., Vasmatzis, G. & Kovtun, I. V., Jan 1 2018, (Accepted/In press) In : Molecular Oncology.

Research output: Contribution to journalArticle

Heterografts
Ovarian Neoplasms
Drug Therapy
Neoplasms
Therapeutics
7 Citations (Scopus)

UCH-L1 bypasses mTOR to promote protein biosynthesis and is required for MYC-driven lymphomagenesis in mice

Hussain, S., Bedekovics, T., Liu, Q., Hu, W., Jeon, H., Johnson, S. H., Vasmatzis, G., May, D. G., Roux, K. J. & Galardy, P. J., Dec 13 2018, In : Blood. 132, 24, p. 2564-2574 11 p.

Research output: Contribution to journalArticle

Biosynthesis
Protein Biosynthesis
Sirolimus
Proteins
B-Lymphocytes
5 Citations (Scopus)

YAP-associated chromosomal instability and cholangiocarcinoma in mice

Rizvi, S., Fischbach, S. R., Bronk, S. F., Hirsova, P., Krishnan, A., Dhanasekaran, R., Smadbeck, J. B., Smoot, R. L., Vasmatzis, G. & Gores, G. J., Jan 1 2018, In : Oncotarget. 9, 5, p. 5892-5905 14 p.

Research output: Contribution to journalArticle

Chromosomal Instability
Cholangiocarcinoma
Proteins
Thiostrepton
Hepatocyte Nuclear Factor 4
5 Citations (Scopus)

YAP tyrosine phosphorylation and nuclear localization in cholangiocarcinoma cells are regulated by LCK and independent of LATS activity

Sugihara, T., Werneburg, N. W., Hernandez, M. C., Yang, L., Kabashima, A., Hirsova, P., Yohanathan, L., Sosa, C., Truty, M., Vasmatzis, G., Gores, G. J. & Smoot, R. L., Oct 1 2018, In : Molecular Cancer Research. 16, 10, p. 1556-1567 12 p.

Research output: Contribution to journalArticle

Long-Acting Thyroid Stimulator
Cholangiocarcinoma
Tyrosine
Phosphorylation
Proteins
2017
2 Citations (Scopus)

A novel cytogenetic and molecular characterization of renal metanephric adenoma: Identification of partner genes involved in translocation t(9;15)(p24;q24)

Catic, A., Kurtovic-Kozaric, A., Johnson, S. H., Vasmatzis, G., Pins, M. R. & Kogan, J., Aug 1 2017, In : Cancer genetics. 214-215, p. 9-15 7 p.

Research output: Contribution to journalArticle

Cytogenetics
Adenoma
Kidney
Genes
Cytogenetic Analysis
11 Citations (Scopus)
Squamous Cell Carcinoma
Chromosomes
Genes
DNA Replication
Uterine Cervical Neoplasms
3 Citations (Scopus)

EGFR mediates activation of RET in lung adenocarcinoma with neuroendocrine differentiation characterized by ASCL1 expression

Bhinge, K., Yang, L., Terra, S., Nasir, A., Muppa, P., Aubry, M. C., Yi, J., Janaki, N., Kovtun, I. V., Murphy, S. J., Halling, G., Rahi, H., Mansfield, A., De Andrade, M., Yang, P., Vasmatzis, G., Peikert, T. D. & Kosari, F., 2017, In : Oncotarget. 8, 16, p. 27155-27165 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Adenocarcinoma
Epidermal Growth Factor
Protein Isoforms
Phosphorylation

Genomic rearrangements in sporadic lymphangioleiomyomatosis: An evolving genetic story

Murphy, S. J., Terra, S. B., Harris, F. R., Nasir, A., Voss, J. S., Smadbeck, J. B., Johnson, S. H., Serla, V., Ryu, J. H., Yi, E. S., Kipp, B. R., Vasmatzis, G. & Carmona Porquera, E. M., Sep 1 2017, In : Modern Pathology. 30, 9, p. 1223-1233 11 p.

Research output: Contribution to journalArticle

Lymphangioleiomyomatosis
Mutation
Tuberous Sclerosis
Mosaicism
Aneuploidy
5 Citations (Scopus)

Identification of a pyruvate-to-lactate signature in pancreatic intraductal papillary mucinous neoplasms

Penheiter, A. R., Deelchand, D. K., Kittelson, E., Damgard, S. E., Murphy, S. J., O'Brien, D. R., Bamlet, W. R., Passow, M. R., Smyrk, T. C., Couch, F. J., Vasmatzis, G., Port, J. D., Marjańska, M. & Carlson, S. K., Jan 1 2017, (Accepted/In press) In : Pancreatology.

Research output: Contribution to journalArticle

Pyruvic Acid
Lactic Acid
Adenocarcinoma
Neoplasms
Immunohistochemistry
5 Citations (Scopus)

Management of Multifocal Lung Cancer: Results of a Survey

Leventakos, K., Peikert, T. D., Midthun, D. E., Molina, J. R., Blackmon, S., Nichols, F. C., Garces, Y. I., Hallemeier, C. L., Murphy, S. J., Vasmatzis, G., Kratz, S. L., Holland, W. P., Thomas, C. F., Mullon, J. J., Shen, K. R., Cassivi, S. D., Marks, R. S., Aubry, M. C., Adjei, A., Yang, P. & 4 others, Allen, M. S., Edell, E., Wigle, D. A. & Mansfield, A., 2017, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Lung Neoplasms
Neoplasm Metastasis
Mediastinoscopy
Mediastinum
Bronchoscopy
2 Citations (Scopus)

Mantle cell lymphoma with a novel t(11;12)(q13;p11.2): a proposed alternative mechanism of CCND1 up-regulation

Menke, J. R., Vasmatzis, G., Murphy, S., Yang, L., Menke, D. M., Tun, H. W., King, R. L., Smoley, S. A., Ketterling, R. P. & Sukov, W. R., Jun 1 2017, In : Human Pathology. 64, p. 207-212 6 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
3' Untranslated Regions
Up-Regulation
Cyclin D1
Chromosome Breakage
1 Citation (Scopus)

Microbial Antigens Stimulate Metalloprotease-7 Secretion in Human B-Lymphocytes Using mTOR-Dependent and Independent Pathways

Ali, M. F., Dasari, H., Van Keulen, V. P., Cornec, D., Vasmatzis, G., Peikert, T. D. & Carmona Porquera, E. M., Dec 1 2017, In : Scientific Reports. 7, 1, 3869.

Research output: Contribution to journalArticle

Metalloproteases
Matrix Metalloproteinases
B-Lymphocytes
Antigens
Syndecan-4
2 Citations (Scopus)

Retention of interstitial genes between TMPRSS2 and ERG is associated with low-risk prostate cancer

Murphy, S. J., Kosari, F., Karnes, R. J., Nasir, A., Johnson, S. H., Gaitatzes, A. G., Smadbeck, J., Rangel, L. J., Vasmatzis, G. & Cheville, J., Nov 15 2017, In : Cancer Research. 77, 22, p. 6157-6167 11 p.

Research output: Contribution to journalArticle

Gene Fusion
Prostatic Neoplasms
Genes
Neoplasms
Prostatectomy
19 Citations (Scopus)

TFEB-VEGFA (6p21.1) co-amplified renal cell carcinoma: A distinct entity with potential implications for clinical management

Gupta, S., Johnson, S. H., Vasmatzis, G., Porath, B., Rustin, J. G., Rao, P., Costello, B., Leibovich, B. C., Houston Thompson, R., Cheville, J. C. & Sukov, W. R., Jul 1 2017, In : Modern Pathology. 30, 7, p. 998-1012 15 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Atlases
Vascular Endothelial Growth Factor A
Neoplasms
Genome
24 Citations (Scopus)

Trinucleotide repeat expansion in the transcription factor 4 (TCF4) gene leads to widespread mrna splicing changes in fuchs’ endothelial corneal dystrophy

Wieben, E. D., Aleff, R. A., Tang, X., Butz, M. L., Kalari, K. R., Highsmith, W. E. J., Jen, J., Vasmatzis, G., Patel, S. V., Maguire, L. J., Baratz, K. & Fautsch, M. P., Jan 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 1, p. 343-352 10 p.

Research output: Contribution to journalArticle

Fuchs' Endothelial Dystrophy
Trinucleotide Repeat Expansion
Corneal Endothelium
Transcription Factors
Genes
2016
12 Citations (Scopus)

Chromoplectic TPM3-ALK rearrangement in a patient with inflammatory myofibroblastic tumor who responded to ceritinib after progression on crizotinib

Mansfield, A., Murphy, S. J., Harris, F. R., Robinson, S., Marks, R. S., Johnson, S. H., Smadbeck, J. B., Halling, G. C., Yi, E. S., Wigle, D. A., Vasmatzis, G. & Jen, J., Nov 1 2016, In : Annals of oncology : official journal of the European Society for Medical Oncology. 27, 11, p. 2111-2117 7 p.

Research output: Contribution to journalArticle

Neoplasms
Sarcoma
ceritinib
crizotinib
Therapeutics
20 Citations (Scopus)

Custom gene capture and next-generation sequencing to resolve discordant ALK status by FISH and IHC in lung adenocarcinoma

Jang, J. S., Wang, X., Vedell, P. T., Wen, J., Zhang, J., Ellison, D. W., Evans, J. M., Johnson, S. H., Yang, P., Sukov, W. R., Oliveir, A. M., Vasmatzis, G., Sun, Z. D., Jen, J. & Yi, E. S., Nov 13 2016, In : Journal of Thoracic Oncology. 11, 11, p. 1891-1900 10 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Genes
Gene Fusion
Clone Cells
Adenocarcinoma of lung
59 Citations (Scopus)

Heterogeneity of Programmed Cell Death Ligand 1 Expression in Multifocal Lung Cancer

Mansfield, A., Murphy, S. J., Peikert, T. D., Yi, E. S., Vasmatzis, G., Wigle, D. A. & Aubry, M. C., May 1 2016, In : Clinical Cancer Research. 22, 9, p. 2177-2182 6 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Cell Death
Ligands
Neoplasms
Selection Bias
18 Citations (Scopus)

Integrated analysis of the genomic instability of PTEN in clinically insignificant and significant prostate cancer

Murphy, S. J., Karnes, R. J., Kosari, F., Castellar, B. E. R. P., Kipp, B. R., Johnson, S. H., Terra, S., Harris, F. R., Halling, G. C., Klein, J. L. S., Nasir, A., Bergstrahl, E., Rangel, L. J., Sukov, W. R., Vasmatzis, G. & Cheville, J. C., Feb 1 2016, In : Modern Pathology. 29, 2, p. 143-156 14 p.

Research output: Contribution to journalArticle

Genomic Instability
Prostatic Neoplasms
Neoplasm Grading
Neoplasms
Fluorescence In Situ Hybridization
15 Citations (Scopus)

Integrated genomic analysis of pancreatic ductal adenocarcinomas reveals genomic rearrangement events as significant drivers of disease

Murphy, S. J., Hart, S., Halling, G. C., Johnson, S. H., Smadbeck, J. B., Drucker, T., Lima, J. F., Rohakhtar, F. R., Harris, F. R., Kosari, F., Subramanian, S., Petersen, G. M., Wiltshire, T. D., Kipp, B. R., Truty, M., Mc Williams, R. R., Couch, F. J. & Vasmatzis, G., Feb 1 2016, In : Cancer Research. 76, 3, p. 749-761 13 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Disease Progression
Genes
Exome
Gene Dosage
41 Citations (Scopus)

Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

Boddicker, R. L., Razidlo, G., Dasari, S., Zeng, Y., Hu, G., Knudson, R. A., Greipp, P. T., Davila, J. I., Johnson, S. H., Porcher, J. C., Smadbeck, J. B., Eckloff, B. W., Billadeau, D. D., Kurtin, P. J., Mc Niven, M. A., Link, B. K., Ansell, S. M., Cerhan, J. R., Asmann, Y., Vasmatzis, G. & 1 others, Feldman, A. L., Sep 1 2016, In : Blood. 128, 9, p. 1234-1245 12 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
RNA Sequence Analysis
T-cells
Gene Fusion
Fusion reactions
5 Citations (Scopus)

Magnetophoretic-based microfluidic device for DNA Concentration

Shim, S., Shim, J., Taylor, W. R., Kosari, F., Vasmatzis, G., Ahlquist, D. A. & Bashir, R., Apr 1 2016, In : Biomedical Microdevices. 18, 2, p. 1-8 8 p., 28.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Microfluidics
DNA
Nanofluidics
Nucleic acids
3 Citations (Scopus)

Molecular cytology genotyping of primary and metastatic GI stromal tumors by using a custom two-gene targeted next-generation sequencing panel with therapeutic intent

Gleeson, F. C., Kerr, S. E., Kipp, B. R., Voss, J. S., Minot, D. M., Tu, Z. J., Henry, M. R., Vasmatzis, G., Cheville, J. C., Lazaridis, K. N. & Levy, M. J., Jan 24 2016, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Cell Biology
Surgical Pathology
Mutation
Genes
Neoplasms
20 Citations (Scopus)

Quantification of Somatic Chromosomal Rearrangements in Circulating Cell-Free DNA from Ovarian Cancers

Harris, F. R., Kovtun, I. V., Smadbeck, J., Multinu, F., Jatoi, A., Kosari, F., Kalli, K. R., Murphy, S. J., Halling, G. C., Johnson, S. H., Liu, M. C., Mariani, A. & Vasmatzis, G., Jul 20 2016, In : Scientific Reports. 6, 29831.

Research output: Contribution to journalArticle

Ovarian Neoplasms
DNA
Neoplasms
Polymerase Chain Reaction
Tumor Burden
32 Citations (Scopus)

Targeted next generation sequencing of endoscopic ultrasound acquired cytology from ampullary and pancreatic adenocarcinoma has the potential to aid patient stratification for optimal therapy selection

Gleeson, F. C., Kerr, S. E., Kipp, B. R., Voss, J. S., Minot, D. M., Tu, Z. J., Henry, M. R., Graham, R., Vasmatzis, G., Cheville, J., Lazaridis, K. N. & Levy, M. J., 2016, In : Oncotarget. 7, 34, p. 54526-54536 11 p.

Research output: Contribution to journalArticle

Cell Biology
Adenocarcinoma
Fine Needle Biopsy
Neoplasm Genes
Mutation
2015
12 Citations (Scopus)

Chromosomal catastrophe is a frequent event in clinically insignificant prostate cancer

Kovtun, I. V., Murphy, S. J., Johnson, S. H., Cheville, J. C. & Vasmatzis, G., 2015, In : Oncotarget. 6, 30, p. 29087-29096 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Neoplasms
Neoplasm Grading
Prostatic Intraepithelial Neoplasia
Chromothripsis
3 Citations (Scopus)

Chromosomal rearrangements and copy number abnormalities of TP63 correlate with p63 protein expression in lung adenocarcinoma

Aubry, M. C., Roden, A., Murphy, S. J., Vasmatzis, G., Johnson, S. H., Harris, F. R., Halling, G., Knudson, R. A., Ketterling, R. P. & Feldman, A. L., Mar 1 2015, In : Modern Pathology. 28, 3, p. 359-366 8 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Adenocarcinoma
Immunohistochemistry
Proteins
Peripheral T-Cell Lymphoma

Clinical validation of a haplotyping method with next-generation sequencing

Cradic, K. W., Murphy, S. J., Sikkink, R. A., Neuhauser, C., Vasmatzis, G. & Grebe, S. K. G., Feb 1 2015, In : Clinical Chemistry. 61, 2, p. 430-431 2 p.

Research output: Contribution to journalArticle

Steroid 21-Hydroxylase