Fergus J Couch

Fergus J Couch, PhD

Chair, Division of Experimental Pathology

1991 …2022

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  • 2010

    Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer

    White, K. L., Sellers, T. A., Fridley, B. L., Vierkant, R. A., Phelan, C. M., Tsai, Y. Y., Kalli, K. R., Berchuck, A., Iversen, E. S., Hartmann, L. C., Liebow, M., Armasu, S., Fredericksen, Z., Larson, M. C., Duggan, D., Couch, F. J., Schildkraut, J. M., Cunningham, J. M. & Goode, E. L., Feb 2010, In: Twin Research and Human Genetics. 13, 1, p. 43-56 14 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • Variation in genes required for normal mitosis and risk of breast cancer

    Olson, J. E., Wang, X., Goode, E. L., Pankratz, V. S., Fredericksen, Z. S., Vierkant, R. A., Pharoah, P. D. P., Cerhan, J. R. & Couch, F. J., Jan 2010, In: Breast Cancer Research and Treatment. 119, 2, p. 423-430 8 p.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • 2009

    Association of breast cancer susceptibility variants with risk of pancreatic cancer

    Couch, F. J., Wang, X., McWilliams, R. R., Bamlet, W. R., De Andrade, M. & Petersen, G. M., Nov 2009, In: Cancer Epidemiology Biomarkers and Prevention. 18, 11, p. 3044-3048 5 p.

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations
  • Association of ESR1 gene tagging SNPs with breast cancer risk

    Dunning, A. M., Healey, C. S., Baynes, C., Maia, A. T., Scollen, S., Vega, A., Rodríguez, R., Barbosa-Morais, N. L., Ponder, B. A. J., Low, Y. L., Bingham, S., Haiman, C. A., Le Marchand, L., Broeks, A., Schmidt, M. K., Hopper, J., Southey, M., Beckmann, M. W., Fasching, P. A., Peto, J., & 50 othersJohnson, N., Bojesen, S. E., Nordestgaard, B., Milne, R. L., Benitez, J., Hamann, U., Ko, Y., Schmutzler, R. K., Burwinkel, B., Schürmann, P., Dörk, T., Heikkinen, T., Nevanlinna, H., Lindblom, A., Margolin, S., Mannermaa, A., Kosma, V. M., Chen, X., Spurdle, A., Change-Claude, J., Flesch-Janys, D., Couch, F. J., Olson, J. E., Severi, G., Baglietto, L., Børresen-Dale, A. L., Kristensen, V., Hunter, D. J., Hankinson, S. E., Devilee, P., Vreeswijk, M., Lissowska, J., Brinton, L., Liu, J., Hall, P., Kang, D., Yoo, K. Y., Shen, C. Y., Yu, J. C., Anton-Culver, H., Ziogoas, A., Sigurdson, A., Struewing, J., Easton, D. F., Garcia-Closas, M., Humphreys, M. K., Morrison, J., Pharoah, P. D. P., Pooley, K. A. & Chenevix-Trench, G., 2009, In: Human molecular genetics. 18, 6, p. 1131-1139 9 p.

    Research output: Contribution to journalArticlepeer-review

    74 Scopus citations
  • Cell cycle genes and ovarian cancer susceptibility: A tagSNP analysis

    Cunningham, J. M., Vierkant, R. A., Sellers, T. A., Phelan, C., Rider, D. N., Liebow, M., Schildkraut, J., Berchuck, A., Couch, F. J., Wang, X., Fridley, B. L., Gentry-Maharaj, A., Menon, U., Hogdall, E., Kjaer, S., Whittemore, A., Dicioccio, R., Song, H., Gayther, S. A., Ramus, S. J., & 2 othersPharaoh, P. D. P. & Goode, E. L., Oct 20 2009, In: British journal of cancer. 101, 8, p. 1461-1468 8 p.

    Research output: Contribution to journalArticlepeer-review

    35 Scopus citations
  • Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

    Antoniou, A. C., Sinilnikova, O. M., McGuffog, L., Healey, S., Nevanlinna, H., Heikkinen, T., Simard, J., Spurdle, A. B., Beesley, J., Chen, X., Neuhausen, S. L., Ding, Y. C., Couch, F. J., Wang, X., Fredericksen, Z., Peterlongo, P., Peissel, B., Bonanni, B., Viel, A., Bernard, L., & 117 othersRadice, P., Szabo, C. I., Foretova, L., Zikan, M., Claes, K., Greene, M. H., Mai, P. L., Rennert, G., Lejbkowicz, F., Andrulis, I. L., Ozcelik, H., Glendon, G., Gerdes, A. M., Thomassen, M., Sunde, L., Caligo, M. A., Laitman, Y., Kontorovich, T., Cohen, S., Kaufman, B., Dagan, E., Baruch, R. G., Friedman, E., Harbst, K., Barbany-Bustinza, G., Rantala, J., Ehrencrona, H., Karlsson, P., Domchek, S. M., Nathanson, K. L., Osorio, A., Blanco, I., Lasa, A., Benítez, J., Hamann, U., Hogervorst, F. B. L., Rookus, M. A., Collee, J. M., Devilee, P., Ligtenberg, M. J., van der Luijt, R. B., Aalfs, C. M., Waisfisz, Q., Wijnen, J., van Roozendaal, C. E. P., Peock, S., Cook, M., Frost, D., Oliver, C., Platte, R., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Davidson, R., Chu, C., Eccles, D., Cole, T., Hodgson, S., Godwin, A. K., Stoppa-Lyonnet, D., Buecher, B., Léoné, M., Bressac-de Paillerets, B., Remenieras, A., Caron, O., Lenoir, G. M., Sevenet, N., Longy, M., Ferrer, S. F., Prieur, F., Goldgar, D., Miron, A., John, E. M., Buys, S. S., Daly, M. B., Hopper, J. L., Terry, M. B., Yassin, Y., Singer, C., Gschwantler-Kaulich, D., Staudigl, C., Hansen, T. V. O., Barkardottir, R. B., Kirchhoff, T., Pal, P., Kosarin, K., Offit, K., Piedmonte, M., Rodriguez, G. C., Wakeley, K., Boggess, J. F., Basil, J., Schwartz, P. E., Blank, S. V., Toland, A. E., Montagna, M., Casella, C., Imyanitov, E. N., Allavena, A., Schmutzler, R. K., Versmold, B., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Niederacher, D., Deißler, H., Fiebig, B., Suttner, C., Schönbuchner, I., Gadzicki, D., Caldes, T., de la Hoya, M., Pooley, K. A., Easton, D. F. & Chenevix-Trench, G., 2009, In: Human molecular genetics. 18, 22, p. 4442-4456 15 p.

    Research output: Contribution to journalArticlepeer-review

    91 Scopus citations
  • Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2 (CIMBA)

    Osorio, A., Milne, R. L., Pita, G., Peterlongo, P., Heikkinen, T., Simard, J., Chenevix-Trench, G., Spurdle, A. B., Beesley, J., Chen, X., Healey, S., Neuhausen, S. L., Ding, Y. C., Couch, F. J., Wang, X., Lindor, N., Manoukian, S., Barile, M., Viel, A., Tizzoni, L., & 113 othersSzabo, C. I., Foretova, L., Zikan, M., Claes, K., Greene, M. H., Mai, P., Rennert, G., Lejbkowicz, F., Barnett-Griness, O., Andrulis, I. L., Ozcelik, H., Weerasooriya, N., Gerdes, A. M., Thomassen, M., Cruger, D. G., Caligo, M. A., Friedman, E., Kaufman, B., Laitman, Y., Cohen, S., Kontorovich, T., Gershoni-Baruch, R., Dagan, E., Jernström, H., Askmalm, M. S., Arver, B., Malmer, B., Domchek, S. M., Nathanson, K. L., Brunet, J., Ramón Y Cajal, T., Yannoukakos, D., Hamann, U., Hogervorst, F. B. L., Verhoef, S., Garcíla, E. B. G., Wijnen, J. T., Van Den Ouweland, A., Easton, D. F., Peock, S., Cook, M., Oliver, C. T., Frost, D., Luccarini, C., Evans, D. G., Lalloo, F., Eeles, R., Pichert, G., Cook, J., Hodgson, S., Morrison, P. J., Douglas, F., Godwin, A. K., Sinilnikova, O. M., Barjhoux, L., Stoppa-Lyonnet, D., Moncoutier, V., Giraud, S., Cassini, C., Olivier-Faivre, L., Révillion, F., Peyrat, J. P., Muller, D., Fricker, J. P., Lynch, H. T., John, E. M., Buys, S., Daly, M., Hopper, J. L., Terry, M. B., Miron, A., Yassin, Y., Goldgar, D., Singer, C. F., Gschwantler-Kaulich, D., Pfeiler, G., Spiess, A. C., Hansen, T. V. O., Johannsson, O. T., Kirchhoff, T., Offit, K., Kosarin, K., Piedmonte, M., Rodriguez, G. C., Wakeley, K., Boggess, J. F., Basil, J., Schwartz, P. E., Blank, S. V., Toland, A. E., Montagna, M., Casella, C., Imyanitov, E. N., Allavena, A., Schmutzler, R. K., Versmold, B., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Niederacher, D., Deiler, H., Fiebig, B., Varon-Mateeva, R., Schaefer, D., Froster, U. G., Caldes, T., De La Hoya, M., McGuffog, L., Antoniou, A. C., Nevanlinna, H., Radice, P. & Benítez, J., Dec 2009, In: British journal of cancer. 101, 12, p. 2048-2054 7 p.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • Five polymorphisms and breast cancer risk: Results from the breast cancer association consortium

    Gaudet, M. M., Milne, R. L., Cox, A., Camp, N. J., Goode, E. L., Humphreys, M. K., Dunning, A. M., Morrison, J., Giles, G. G., Severi, G., Baglietto, L., English, D. R., Couch, F. J., Olson, J. E., Wang, X., Chang-Claude, J., Flesch-Janys, D., Abbas, S., Salazar, R., Mannermaa, A., & 95 othersKataja, V., Kosma, V. M., Lindblom, A., Margolin, S., Heikkinen, T., Kämpjärvi, K., Aaltonen, K., Nevanlinna, H., Bogdanova, N., Coinac, I., Schürmann, P., Dörk, T., Bartram, C. R., Schmutzler, R. K., Tchatchou, S., Burwinkel, B., Brauch, H., Torres, D., Hamann, U., Justenhoven, C., Ribas, G., Arias, J. I., Benitez, J., Bojesen, S. E., Nordestgaard, B. G., Flyger, H. L., Peto, J., Fletcher, O., Johnson, N., Silva, I. D. S., Fasching, P. A., Beckmann, M. W., Strick, R., Ekici, A. B., Broeks, A., Schmidt, M. K., Van Leeuwen, F. E., Van't Veer, L. J., Southey, M. C., Hopper, J. L., Apicella, C., Haiman, C. A., Henderson, B. E., Le Marchand, L., Kolonel, L. N., Kristensen, V., Alnæs, G. G., Hunter, D. J., Kraft, P., Cox, D. G., Hankinson, S. E., Seynaeve, C., Vreeswijk, M. P. G., Tollenaar, R. A. E. M., Devilee, P., Chanock, S., Lissowska, J., Brinton, L., Peplonska, B., Czene, K., Hall, P., Li, Y., Liu, J., Balasubramanian, S., Rafii, S., Reed, M. W. R., Pooley, K. A., Conroy, D., Baynes, C., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Shen, C. Y., Wang, H. C., Yu, J. C., Wu, P. E., Anton-Culver, H., Ziogoas, A., Egan, K., Newcomb, P., Titus-Ernstoff, L., Dietz, A. T., Sigurdson, A. J., Alexander, B. H., Bhatti, P., Allen-Brady, K., Cannon-Albright, L. A., Wong, J., Chenevix-Trench, G., Spurdle, A. B., Beesley, J., Pharoah, P. D. P., Easton, D. F. & Garcia-Closas, M., May 2009, In: Cancer Epidemiology Biomarkers and Prevention. 18, 5, p. 1610-1616 7 p.

    Research output: Contribution to journalArticlepeer-review

    53 Scopus citations
  • Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma

    Sakai, W., Swisher, E. M., Jacquemont, C., Chandramohan, K. V., Couch, F. J., Langdon, S. P., Wurz, K., Higgins, J., Villegas, E. & Taniguchi, T., Aug 15 2009, In: Cancer research. 69, 16, p. 6381-6386 6 p.

    Research output: Contribution to journalArticlepeer-review

    204 Scopus citations
  • Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers

    Neuhausen, S. L., Brummel, S., Ding, Y. C., Singer, C. F., Pfeiler, G., Lynch, H. T., Nathanson, K. L., Rebbeck, T. R., Garber, J. E., Couch, F., Weitzel, J., Narod, S. A., Ganz, P. A., Daly, M. B., Godwin, A. K., Isaacs, C., Olopade, O. I., Tomlinson, G., Rubinstein, W. S., Tung, N., & 2 othersBlum, J. L. & Gillen, D. L., Oct 20 2009, In: Breast Cancer Research. 11, 5, R76.

    Research output: Contribution to journalArticlepeer-review

    38 Scopus citations
  • Genetic variation in the chromosome 17q23 amplicon and breast cancer risk

    Kelemen, L. E., Wang, X., Fredericksen, Z. S., Pankratz, V. S., Pharoah, P. D. P., Ahmed, S., Dunning, A. M., Easton, D. F., Vierkant, R. A., Cerhan, J. R., Goode, E. L., Olson, J. E. & Couch, F. J., Jun 2009, In: Cancer Epidemiology Biomarkers and Prevention. 18, 6, p. 1864-1868 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    25 Scopus citations
  • Microcephalin regulates BRCA2 and Rad51-associated DNA double-strand break repair

    Wu, X., Mondal, G., Wang, X., Wu, J., Yang, L., Pankratz, V. S., Rowley, M. & Couch, F. J., Jul 1 2009, In: Cancer research. 69, 13, p. 5531-5536 6 p.

    Research output: Contribution to journalArticlepeer-review

    41 Scopus citations
  • Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers

    Rebbeck, T. R., Mitra, N., Domchek, S. M., Wan, F., Chuai, S., Friebel, T. M., Panossian, S., Spurdle, A., Chenevix-Trench, G., Singer, C. F., Pfeiler, G., Neuhausen, S. L., Lynch, H. T., Garber, J. E., Weitzel, J. N., Isaacs, C., Couch, F., Narod, S. A., Rubinstein, W. S., Tomlinson, G. E., & 7 othersGanz, P. A., Olopade, O. I., Tung, N., Blum, J. L., Greenberg, R., Nathanson, K. L. & Daly, M. B., Jul 15 2009, In: Cancer research. 69, 14, p. 5801-5810 10 p.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2

    Ahmed, S., Thomas, G., Ghoussaini, M., Healey, C. S., Humphreys, M. K., Platte, R., Morrison, J., Maranian, M., Pooley, K. A., Luben, R., Eccles, D., Evans, D. G., Fletcher, O., Johnson, N., Dos Santos Silva, I., Peto, J., Stratton, M. R., Rahman, N., Jacobs, K., Prentice, R., & 115 othersAnderson, G. L., Rajkovic, A., Curb, J. D., Ziegler, R. G., Berg, C. D., Buys, S. S., McCarty, C. A., Feigelson, H. S., Calle, E. E., Thun, M. J., Diver, W. R., Bojesen, S., Nordestgaard, B. G., Flyger, H., Dörk, T., Schürmann, P., Hillemanns, P., Karstens, J. H., Bogdanova, N. V., Antonenkova, N. N., Zalutsky, I. V., Bermisheva, M., Fedorova, S., Khusnutdinova, E., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Devilee, P., Van Asperen, C. J., Tollenaar, R. A. E. M., Seynaeve, C., Garcia-Closas, M., Lissowska, J., Brinton, L., Peplonska, B., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Hopper, J. L., Southey, M. C., Smith, L., Spurdle, A. B., Schmidt, M. K., Broeks, A., Van Hien, R. R., Cornelissen, S., Milne, R. L., Ribas, G., González-Neira, A., Benitez, J., Schmutzler, R. K., Burwinkel, B., Bartram, C. R., Meindl, A., Brauch, H., Justenhoven, C., Hamann, U., Chang-Claude, J., Hein, R., Wang-Gohrke, S., Lindblom, A., Margolin, S., Mannermaa, A., Kosma, V. M., Kataja, V., Olson, J. E., Wang, X., Fredericksen, Z., Giles, G. G., Severi, G., Baglietto, L., English, D. R., Hankinson, S. E., Cox, D. G., Kraft, P., Vatten, L. J., Hveem, K., Kumle, M., Sigurdson, A., Doody, M., Bhatti, P., Alexander, B. H., Hooning, M. J., Van Den Ouweland, A. M. W., Oldenburg, R. A., Schutte, M., Hall, P., Czene, K., Liu, J., Li, Y., Cox, A., Elliott, G., Brock, I., Reed, M. W. R., Shen, C. Y., Yu, J. C., Hsu, G. C., Chen, S. T., Anton-Culver, H., Ziogas, A., Andrulis, I. L., Knight, J. A., Beesley, J., Goode, E. L., Couch, F., Chenevix-Trench, G., Hoover, R. N., Ponder, B. A. J., Hunter, D. J., Pharoah, P. D. P., Dunning, A. M., Chanock, S. J. & Easton, D. F., May 2009, In: Nature Genetics. 41, 5, p. 585-590 6 p.

    Research output: Contribution to journalArticlepeer-review

    387 Scopus citations
  • No association between a candidate TCF7L2 variant and risk of breast or ovarian cancer

    Goode, E. L., Szabo, C., Prokunina-Olsson, L., Vierkant, R. A., Fredericksen, Z. S., Collins, F. S., White, K. L., Schmidt, M., Fridley, B. L. & Couch, F. J., Sep 4 2009, In: BMC cancer. 9, p. 312 1 p., 312.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: A multi-center cohort study

    Rebbeck, T. R., Antoniou, A. C., Llopis, T. C., Nevanlinna, H., Aittomäki, K., Simard, J., Spurdle, A. B., Couch, F. J., Pereira, L. H. M., Greene, M. H., Andrulis, I. L., Pasche, B., Kaklamani, V., Hamann, U., Szabo, C., Peock, S., Cook, M., Harrington, P. A., Donaldson, A., Male, A. M., & 24 othersGardiner, C. A., Gregory, H., Side, L. E., Robinson, A. C., Emmerson, L., Ellis, I., Peyrat, J. P., Fournier, J., Vennin, P., Adenis, C., Muller, D., Fricker, J. P., Longy, M., Sinilnikova, O. M., Stoppa-Lyonnet, D., Schmutzler, R. K., Versmold, B., Engel, C., Meindl, A., Kast, K., Schaefer, D., Froster, U. G., Chenevix-Trench, G. & Easton, D. F., May 1 2009, In: Breast Cancer Research and Treatment. 115, 1, p. 185-192 8 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • No evidence that GATA3 rs570613 SNP modifies breast cancer risk

    Johnatty, S. E., Couch, F. J., Fredericksen, Z., Tarrell, R., Spurdle, A. B., Beesley, J., Chen, X., Gschwantler-Kaulich, D., Singer, C. F., Fuerhauser, C., Fink-Retter, A., Domchek, S. M., Nathanson, K. L., Pankratz, V. S., Lindor, N. M., Godwin, A. K., Caligo, M. A., Hopper, J., Southey, M. C., Giles, G. G., & 45 othersJustenhoven, C., Brauch, H., Hamann, U., Ko, Y. D., Heikkinen, T., Aaltonen, K., Aittomäki, K., Blomqvist, C., Nevanlinna, H., Hall, P., Czene, K., Liu, J., Peock, S., Cook, M., Platte, R., Gareth Evans, D., Lalloo, F., Eeles, R., Pichert, G., Eccles, D., Davidson, R., Cole, T., Cook, J., Douglas, F., Chu, C., Hodgson, S., Paterson, J., Hogervorst, F. B. L., Rookus, M. A., Seynaeve, C., Wijnen, J., Vreeswijk, M., Ligtenberg, M., Van Der Luijt, R. B., Van Os, T. A. M., Gille, H. J. P., Blok, M. J., Issacs, C., Humphreys, M. K., McGuffog, L., Healey, S., Sinilnikova, O., Antoniou, A. C., Easton, D. F. & Chenevix-Trench, G., Sep 2009, In: Breast Cancer Research and Treatment. 117, 2, p. 371-379 9 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk

    McWilliams, R. R., Bamlet, W. R., De Andrade, M., Rider, D. N., Couch, F. J., Cunningham, J. M., Matsumoto, M. E., Rabe, K. G., Hammer, T. J. & Petersen, G. M., Sep 2009, In: Cancer Epidemiology Biomarkers and Prevention. 18, 9, p. 2549-2552 4 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042

    Milne, R. L., Benítez, J., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Arias, J. I., Zamora, M. P., Burwinkel, B., Bartram, C. R., Meindl, A., Schmutzler, R. K., Cox, A., Brock, I., Elliott, G., Reed, M. W. R., Southey, M. C., Smith, L., Spurdle, A. B., Hopper, J. L., & 73 othersCouch, F. J., Olson, J. E., Wang, X., Fredericksen, Z., Schürmann, P., Bremer, M., Hillemanns, P., Dörk, T., Devilee, P., Van Asperen, C. J., Tollenaar, R. A. E. M., Seynaeve, C., Hall, P., Czene, K., Liu, J., Li, Y., Ahmed, S., Dunning, A. M., Maranian, M., Pharoah, P. D. P., Chenevix-Trench, G., Beesley, J., Bogdanova, N. V., Antonenkova, N. N., Zalutsky, I. V., Anton-Culver, H., Ziogas, A., Brauch, H., Justenhoven, C., Ko, Y. D., Haas, S., Fasching, P. A., Strick, R., Ekici, A. B., Beckmann, M. W., Giles, G. G., Severi, G., Baglietto, L., English, D. R., Fletcher, O., Johnson, N., Dos Santos Silva, I., Peto, J., Turnbull, C., Hines, S., Renwick, A., Rahman, N., Nordestgaard, B. G., Bojesen, S. E., Flyger, H., Kang, D., Yoo, K. Y., Noh, D. Y., Mannermaa, A., Kataja, V., Kosma, V. M., García-Closas, M., Chanock, S., Lissowska, J., Brinton, L. A., Chang-Claude, J., Wang-Gohrke, S., Shen, C. Y., Wang, H. C., Yu, J. C., Chen, S. T., Bermisheva, M., Nikolaeva, T., Khusnutdinova, E., Humphreys, M. K., Morrison, J., Platte, R. & Easton, D. F., Jul 2009, In: Journal of the National Cancer Institute. 101, 14, p. 1012-1018 7 p.

    Research output: Contribution to journalArticlepeer-review

    94 Scopus citations
  • Trends in mastectomy rates at the Mayo Clinic Rochester: Effect of surgical year and preoperative magnetic resonance imaging

    Katipamula, R., Degnim, A. C., Hoskin, T., Boughey, J. C., Loprinzi, C., Grant, C. S., Brandt, K. R., Pruthi, S., Chute, C. G., Olson, J. E., Couch, F. J., Ingle, J. N. & Goetz, M. P., Sep 1 2009, In: Journal of Clinical Oncology. 27, 25, p. 4082-4088 7 p.

    Research output: Contribution to journalArticlepeer-review

    302 Scopus citations
  • 2008

    Allele-specific expression in the germline of patients with familial pancreatic cancer: An unbiased approach to cancer gene discovery

    Aik, C. T., Fan, J. B., Karikari, C., Bibikova, M., Garcia, E. W., Zhou, L., Barker, D., Serre, D., Feldmann, G., Hruban, R. H., Klein, A. P., Goggins, M., Couch, F. J., Hudson, T. J., Winslow, R. L., Maitra, A. & Chakravarti, A., Jan 2008, In: Cancer Biology and Therapy. 7, 1, p. 137-146 10 p.

    Research output: Contribution to journalArticlepeer-review

    37 Scopus citations
  • Association of genetic variation in genes implicated in the β-catenin destruction complex with risk of breast cancer

    Wang, X., Goode, E. L., Fredericksen, Z. S., Vierkant, R. A., Pankratz, V. S., Liu-Mares, W., Rider, D. N., Vachon, C. M., Cerhan, J. R., Olson, J. E. & Couch, F. J., Aug 2008, In: Cancer Epidemiology Biomarkers and Prevention. 17, 8, p. 2101-2108 8 p.

    Research output: Contribution to journalArticlepeer-review

    66 Scopus citations
  • Classifying variants of undetermined significance in BRCA2 with protein likelihood ratios

    Karchin, R., Agarwal, M., Sali, A., Couch, F. & Beattie, M. S., 2008, In: Cancer Informatics. 6, p. 203-216 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    40 Scopus citations
  • Clinically applicable models to characterize BRCA1 and BRCA2 variants of uncertain significance

    Spearman, A. D., Sweet, K., Zhou, X. P., McLennan, J., Couch, F. J. & Toland, A. E., Nov 20 2008, In: Journal of Clinical Oncology. 26, 33, p. 5393-5400 8 p.

    Research output: Contribution to journalArticlepeer-review

    65 Scopus citations
  • Common Breast Cancer-Predisposition Alleles Are Associated with Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

    Antoniou, A. C., Spurdle, A. B., Sinilnikova, O. M., Healey, S., Pooley, K. A., Schmutzler, R. K., Versmold, B., Engel, C., Meindl, A., Arnold, N., Hofmann, W., Sutter, C., Niederacher, D., Deissler, H., Caldes, T., Kämpjärvi, K., Nevanlinna, H., Simard, J., Beesley, J., Chen, X., & 66 othersNeuhausen, S. L., Rebbeck, T. R., Wagner, T., Lynch, H. T., Isaacs, C., Weitzel, J., Ganz, P. A., Daly, M. B., Tomlinson, G., Olopade, O. I., Blum, J. L., Couch, F. J., Peterlongo, P., Manoukian, S., Barile, M., Radice, P., Szabo, C. I., Pereira, L. H. M., Greene, M. H., Rennert, G., Lejbkowicz, F., Barnett-Griness, O., Andrulis, I. L., Ozcelik, H., Gerdes, A. M., Caligo, M. A., Laitman, Y., Kaufman, B., Milgrom, R., Friedman, E., Domchek, S. M., Nathanson, K. L., Osorio, A., Llort, G., Milne, R. L., Benítez, J., Hamann, U., Hogervorst, F. B. L., Manders, P., Ligtenberg, M. J. L., van den Ouweland, A. M. W., Peock, S., Cook, M., Platte, R., Evans, D. G., Eeles, R., Pichert, G., Chu, C., Eccles, D., Davidson, R., Douglas, F., Godwin, A. K., Barjhoux, L., Mazoyer, S., Sobol, H., Bourdon, V., Eisinger, F., Chompret, A., Capoulade, C., Bressac-de Paillerets, B., Lenoir, G. M., Gauthier-Villars, M., Houdayer, C., Stoppa-Lyonnet, D., Chenevix-Trench, G. & Easton, D. F., Apr 11 2008, In: American journal of human genetics. 82, 4, p. 937-948 12 p.

    Research output: Contribution to journalArticlepeer-review

    223 Scopus citations
  • Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: Combining inherited and tumor gene markers for prediction of tamoxifen resistance

    Goetz, M. P., Suman, V. J., Couch, F. J., Ames, M. M., Rae, J. M., Erlander, M. G., Ma, X. J., Sgroi, D. C., Reynolds, C. A., Lingle, W. L., Weinshilboum, R. M., Flockhart, D. A., Desta, Z., Perez, E. A. & Ingle, J. N., Sep 15 2008, In: Clinical Cancer Research. 14, 18, p. 5864-5868 5 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Functional assays for classification of BRCA2 variants of uncertain significance

    Farrugia, D. J., Agarwal, M. K., Pankratz, V. S., Deffenbaugh, A. M., Pruss, D., Frye, C., Wadum, L., Johnson, K., Mentlick, J., Tavtigian, S. V., Goldgar, D. E. & Couch, F. J., May 1 2008, In: Cancer research. 68, 9, p. 3523-3531 9 p.

    Research output: Contribution to journalArticlepeer-review

    95 Scopus citations
  • Genetic variation in stromal proteins decorin and lumican with breast cancer: Investigations in two case-control studies

    Kelemen, L. E., Couch, F. J., Ahmed, S., Dunning, A. M., Pharoah, P. D. P., Easton, D. F., Fredericksen, Z. S., Vierkant, R. A., Pankratz, V. S., Goode, E. L., Scott, C. G., Rider, D. N., Wang, X., Cerhan, J. R. & Vachon, C. M., Nov 26 2008, In: Breast Cancer Research. 10, 6, R98.

    Research output: Contribution to journalArticlepeer-review

    36 Scopus citations
  • Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

    Garcia-Closas, M., Hall, P., Nevanlinna, H., Pooley, K., Morrison, J., Richesson, D. A., Bojesen, S. E., Nordestgaard, B. G., Axelsson, C. K., Arias, J. I., Milne, R. L., Ribas, G., González-Neira, A., Benítez, J., Zamora, P., Brauch, H., Justenhoven, C., Hamann, U., Ko, Y. D., Bruening, T., & 91 othersHaas, S., Dörk, T., Schürmann, P., Hillemanns, P., Bogdanova, N., Bremer, M., Karstens, J. H., Fagerholm, R., Aaltonen, K., Aittomäki, K., Von Smitten, K., Blomqvist, C., Mannermaa, A., Uusitupa, M., Eskelinen, M., Tengström, M., Kosma, V. M., Kataja, V., Chenevix-Trench, G., Spurdle, A. B., Beesley, J., Chen, X., Devilee, P., Van Asperen, C. J., Jacobi, C. E., Tollenaar, R. A. E. M., Huijts, P. E. A., Klijn, J. G. M., Chang-Claude, J., Kropp, S., Slanger, T., Flesch-Janys, D., Mutschelknauss, E., Salazar, R., Wang-Gohrke, S., Couch, F., Goode, E. L., Olson, J. E., Vachon, C., Fredericksen, Z. S., Giles, G. G., Baglietto, L., Severi, G., Hopper, J. L., English, D. R., Southey, M. C., Haiman, C. A., Henderson, B. E., Kolonel, L. N., Le Marchand, L., Stram, D. O., Hunter, D. J., Hankinson, S. E., Cox, D. G., Tamimi, R., Kraft, P., Sherman, M. E., Chanock, S. J., Lissowska, J., Brinton, L. A., Peplonska, B., Hooning, M. J., Meijers-Heijboer, H., Collee, J. M., Van Den Ouweland, A., Uitterlinden, A. G., Liu, J., Low, Y. L., Yuqing, L., Humphreys, K., Czene, K., Cox, A., Balasubramanian, S. P., Cross, S. S., Reed, M. W. R., Blows, F., Driver, K., Dunning, A., Tyrer, J., Ponder, B. A. J., Sangrajrang, S., Brennan, P., McKay, J., Odefrey, F., Gabrieau, V., Sigurdson, A., Doody, M., Struewing, J. P., Alexander, B., Easton, D. F. & Pharoah, P. D., Apr 2008, In: PLoS genetics. 4, 4, e1000054.

    Research output: Contribution to journalArticlepeer-review

    279 Scopus citations
  • Hormone therapy and the risk of breast cancer in BRCA1 mutation carriers

    Eisen, A., Lubinski, J., Gronwald, J., Moller, P., Lynch, H. T., Klijn, J., Kim-Sing, C., Neuhausen, S. L., Gilbert, L., Ghadirian, P., Manoukian, S., Rennert, G., Friedman, E., Isaacs, C., Rosen, E., Rosen, B., Daly, M., Sun, P., Narod, S. A., Olopade, O., & 37 othersCummings, S., Tung, N., Couch, F., Foulkes, W. D., Domchek, S., Stoppa-Lyonnet, D., Gershoni-Baruch, R., Horsman, D., Wagner, T., Saal, H., Warner, E., Meschino, W., Offit, K., Trivedi, A., Robson, M., Osborne, M., Gilchrist, D., Eng, C., Weitzel, J., McKinnon, W., Wood, M., Maugard, C., Pasini, B., Ainsworth, P., Sweet, K., Pasche, B., Fallen, T., Karlan, B., Kurz, R. N., Armel, S., Tulman, A., Lemire, E., Mclennan, J., Evans, G., Byrski, T., Huzarski, T. & Shulman, L., Oct 2008, In: Journal of the National Cancer Institute. 100, 19, p. 1361-1367 7 p.

    Research output: Contribution to journalArticlepeer-review

    147 Scopus citations
  • International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers

    Metcalfe, K. A., Birenbaum-Carmeli, D., Lubinski, J., Gronwald, J., Lynch, H., Moller, P., Ghadirian, P., Foulkes, W. D., Klijn, J., Friedman, E., Kim-Sing, C., Ainsworth, P., Rosen, B., Domchek, S., Wagner, T., Tung, N., Manoukian, S., Couch, F., Sun, P., Narod, S. A., & 26 othersDaly, M., Saal, H. M., Sweet, K., Lyonnet, D., Eisen, A., Rennen, G., McLennan, J., Gershoni-Baruch, R., Garber, J., Cummings, S., Weitzel, J., Karlan, B., Kurz, R. N., McKinnon, W., Wood, M., Gilchrist, D., Chudley, A., Osborne, M., Fishman, D., Meschino, W. S., Lemire, E., Maugard, C., Mills, G., Merajver, S., Rayson, D. & Collee, J. M., May 1 2008, In: International Journal of Cancer. 122, 9, p. 2017-2022 6 p.

    Research output: Contribution to journalArticlepeer-review

    262 Scopus citations
  • Mutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancers

    Wang, X., Szabo, C., Qian, C., Amadio, P. G., Thibodeau, S. N., Cerhan, J. R., Petersen, G. M., Liu, W. & Couch, F. J., Feb 15 2008, In: Cancer research. 68, 4, p. 971-975 5 p.

    Research output: Contribution to journalArticlepeer-review

    36 Scopus citations
  • Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter

    Wang, J., Bian, C., Li, J., Couch, F. J., Wu, K. & Zhao, R. C., Dec 26 2008, In: Journal of Biological Chemistry. 283, 52, p. 36249-36256 8 p.

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations
  • Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): A pilot study

    Balan, V., Nangia-Makker, P., Schwartz, A. G., Young, S. J., Tait, L., Hogan, V., Raz, T., Wang, Y., Zeng, Q. Y., Gen, S. W., Guo, Y., Li, H., Abrams, J., Couch, F. J., Lingle, W. L., Lloyd, R. V., Ethier, S. P., Tainsky, M. A. & Raz, A., Dec 15 2008, In: Cancer research. 68, 24, p. 10045-10050 6 p.

    Research output: Contribution to journalArticlepeer-review

    46 Scopus citations
  • Rapid progression of prostate cancer in men with a BRCA2 mutation

    Narod, S. A., Neuhausen, S., Vichodez, G., Armel, S., Lynch, H. T., Ghadirian, P., Cummings, S., Olopade, O., Stoppa-Lyonnet, D., Couch, F., Wagner, T., Warner, E., Foulkes, W. D., Saal, H., Weitzel, J., Tulman, A., Poll, A., Nam, R., Sun, P., Danquah, J., & 19 othersDomchek, S., Tung, N., Ainsworth, P., Horsman, D., Kim-Sing, C., Maugard, C., Eisen, A., Daly, M., McKinnon, W., Wood, M., Isaacs, C., Gilchrist, D., Karlan, B., Nedelcu, R., Meschino, W., Garber, J., Pasini, B., Manoukian, S. & Bellati, C., Jul 22 2008, In: British journal of cancer. 99, 2, p. 371-374 4 p.

    Research output: Contribution to journalArticlepeer-review

    109 Scopus citations
  • Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

    Sakai, W., Swisher, E. M., Karlan, B. Y., Agarwal, M. K., Higgins, J., Friedman, C., Villegas, E., Jacquemont, C., Farrugia, D. J., Couch, F. J., Urban, N. & Taniguchi, T., Feb 28 2008, In: Nature. 451, 7182, p. 1116-1120 5 p.

    Research output: Contribution to journalArticlepeer-review

    691 Scopus citations
  • Spontaneous vulvar papillomas in a colony of mice used for pancreatic cancer research

    Gades, N. M., Ohashi, A., Mills, L. D., Rowley, M. A., Predmore, K. S., Marler, R. J. & Couch, F. J., Jun 2008, In: Comparative medicine. 58, 3, p. 271-275 5 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • 2007

    A common coding variant in CASP8 is associated with breast cancer risk

    Cox, A., Dunning, A. M., Garcia-Closas, M., Balasubramanian, S., Reed, M. W. R., Pooley, K. A., Scollen, S., Baynes, C., Ponder, B. A. J., Chanock, S., Lissowska, J., Brinton, L., Peplonska, B., Southey, M. C., Hopper, J. L., McCredie, M. R. E., Giles, G. G., Fletcher, O., Johnson, N., Dos Santos Silva, I., & 59 othersGibson, L., Bojesen, S. E., Nordestgaard, B. G., Axelsson, C. K., Torres, D., Hamann, U., Justenhoven, C., Brauch, H., Chang-Claude, J., Kropp, S., Risch, A., Wang-Gohrke, S., Schürmann, P., Bogdanova, N., Dörk, T., Fagerholm, R., Aaltonen, K., Blomqvist, C., Nevanlinna, H., Seal, S., Renwick, A., Stratton, M. R., Rahman, N., Sangrajrang, S., Hughes, D., Odefrey, F., Brennan, P., Spurdle, A. B., Chenevix-Trench, G., Beesley, J., Mannermaa, A., Hartikainen, J., Kataja, V., Kosma, V. M., Couch, F. J., Olson, J. E., Goode, E. L., Broeks, A., Schmidt, M. K., Hogervorst, F. B. L., Veer, L. J. V. T., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Wedrén, S., Hall, P., Low, Y. L., Liu, J., Milne, R. L., Ribas, G., Gonzalez-Neira, A., Benitez, J., Sigurdson, A. J., Stredrick, D. L., Alexander, B. H., Struewing, J. P., Pharoah, P. D. P. & Easton, D. F., Mar 2007, In: Nature Genetics. 39, 3, p. 352-358 7 p.

    Research output: Contribution to journalArticlepeer-review

    425 Scopus citations
  • A comprehensive examination of CYP19 variation and breast density

    Olson, J. E., Ma, C. X., Pelleymounter, L. L., Schaid, D. J., Pankratz, V. S., Vierkant, R. A., Fredericksen, Z. S., Ingle, J. N., Wu, Y., Couch, F., Sellers, T. A., Weinshilboum, R. M. & Vachon, C. M., Mar 2007, In: Cancer Epidemiology Biomarkers and Prevention. 16, 3, p. 623-625 3 p.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • A comprehensive examination of CYP19 variation and risk of breast cancer using two haplotype-tagging approaches

    Olson, J. E., Ingle, J. N., Ma, C. X., Pelleymounter, L. L., Schaid, D. J., Pankratz, V. S., Vierkant, R. A., Fredericksen, Z. S., Wu, Y., Couch, F. J., Vachon, C. M., Sellers, T. A. & Weinshilboum, R. M., Apr 2007, In: Breast Cancer Research and Treatment. 102, 2, p. 237-247 11 p.

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations
  • Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

    Kotsopoulos, J., Lubinski, J., Lynch, H. T., Klijn, J., Ghadirian, P., Neuhausen, S. L., Kim-Sing, C., Foulkes, W. D., Moller, P., Isaacs, C., Domchek, S., Randall, S., Offit, K., Tung, N., Ainsworth, P., Gershoni-Baruch, R., Eisen, A., Daly, M., Karlan, B., Saal, H. M., & 26 othersCouch, F., Pasini, B., Wagner, T., Friedman, E., Rennert, G., Eng, C., Weitzel, J., Sun, P., Narod, S. A., Garber, J., Gilchrist, D., Osborne, M., Fishman, D., Warner, E., McLennan, J., McKinnon, W., Merajver, S., Olsson, H., Provencher, D., Pasche, B., Evans, G., Meschino, W. S., Lemire, E., Chudley, A., Rayson, D. & Bellati, C., Oct 2007, In: Breast Cancer Research and Treatment. 105, 2, p. 221-228 8 p.

    Research output: Contribution to journalArticlepeer-review

    40 Scopus citations
  • Association of childhood and adolescent anthropometric factors, physical activity, and diet with adult mammographic breast density

    Sellers, T. A., Vachon, C. M., Pankratz, V. S., Janney, C. A., Fredericksen, Z., Brandt, K. R., Huang, Y., Couch, F. J., Kushi, L. H. & Cerhan, J. R., Jul 2007, In: American journal of epidemiology. 166, 4, p. 456-464 9 p.

    Research output: Contribution to journalArticlepeer-review

    60 Scopus citations
  • A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes

    Easton, D. F., Deffenbaugh, A. M., Pruss, D., Frye, C., Wenstrup, R. J., Allen-Brady, K., Tavtigian, S. V., Monteiro, A. N. A., Iversen, E. S., Couch, F. J. & Goldgar, D. E., 2007, In: American journal of human genetics. 81, 5, p. 873-883 11 p.

    Research output: Contribution to journalArticlepeer-review

    339 Scopus citations
  • AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: A Consortium of Investigators of Modifiers of BRCA1/2 study

    Couch, F. J., Sinilnikova, O., Vierkant, R. A., Pankratz, V. S., Fredericksen, Z. S., Stoppa-Lyonnet, D., Coupier, I., Hughes, D., Hardouin, A., Berthet, P., Peock, S., Cook, M., Baynes, C., Hodgson, S., Morrison, P. J., Porteous, M. E., Jakubowska, A., Lubinski, J., Gronwald, J., Spurdle, A. B., & 51 othersChenevix-Trench, G., Schmutzler, R., Versmold, B., Engel, C., Meindl, A., Sutter, C., Horst, J., Schaefer, D., Offit, K., Kirchhoff, T., Andrulis, I. L., Ilyushik, E., Glendon, G., Devilee, P., Vreeswijk, M. P. G., Vasen, H. F. A., Borg, A., Backenhorn, K., Struewing, J. P., Greene, M. H., Neuhausen, S. L., Rebbeck, T. R., Nathanson, K., Domchek, S., Wagner, T., Garber, J. E., Szabo, C., Zikan, M., Foretova, L., Olson, J. E., Sellers, T. A., Lindor, N., Nevanlinna, H., Tommiska, J., Aittomaki, K., Hamann, U., Rashid, M. U., Torres, D., Simard, J., Durocher, F., Guenard, F., Lynch, H. T., Isaacs, C., Weitzel, J., Olopade, O. I., Narod, S., Daly, M. B., Godwin, A. K., Tomlinson, G., Easton, D. F. & Antoniou, A. C., Jul 1 2007, In: Cancer Epidemiology Biomarkers and Prevention. 16, 7, p. 1416-1421 6 p.

    Research output: Contribution to journalArticlepeer-review

    27 Scopus citations
  • Bilateral prophylactic oophorectomy and bilateral prophylactic mastectomy in a prospective cohort of unaffected BRCA1 and BRCA2 mutation carriers

    Friebel, T. M., Domchek, S. M., Neuhausen, S. L., Wagner, T., Evans, D. G., Isaacs, C., Garber, J. E., Daly, M. B., Eeles, R., Matloff, E., Tomlinson, G., Lynch, H. T., Tung, N., Blum, J. L., Weitzel, J., Rubinstein, W. S., Ganz, P. A., Couch, F. & Rebbeck, T. R., Dec 2007, In: Clinical breast cancer. 7, 11, p. 875-882 8 p.

    Research output: Contribution to journalArticlepeer-review

    61 Scopus citations
  • Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis

    Carvalho, M. A., Marsillac, S. M., Karchin, R., Manoukian, S., Grist, S., Swaby, R. F., Urmenyi, T. P., Rondinelli, E., Silva, R., Gayol, L., Baumbach, L., Sutphen, R., Pickard-Brzosowicz, J. L., Nathanson, K. L., Sali, A., Goldgar, D., Couch, F. J., Radice, P. & Monteiro, A. N. A., Feb 15 2007, In: Cancer research. 67, 4, p. 1494-1501 8 p.

    Research output: Contribution to journalArticlepeer-review

    96 Scopus citations
  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Easton, D. F., Pooley, K. A., Dunning, A. M., Pharoah, P. D. P., Thompson, D., Ballinger, D. G., Struewing, J. P., Morrison, J., Field, H., Luben, R., Wareham, N., Ahmed, S., Healey, C. S., Bowman, R., Meyer, K. B., Haiman, C. A., Kolonel, L. K., Henderson, B. E., Le Marchand, L., Brennan, P., & 212 othersSangrajrang, S., Gaborieau, V., Odefrey, F., Shen, C. Y., Wu, P. E., Wang, H. C., Eccles, D., Evans, D. G., Peto, J., Fletcher, O., Johnson, N., Seal, S., Stratton, M. R., Rahman, N., Chenevix-Trench, G., Bojesen, S. E., Nordestgaard, B. G., Axelsson, C. K., Garcia-Closas, M., Brinton, L., Chanock, S., Lissowska, J., Peplonska, B., Nevanlinna, H., Fagerholm, R., Eerola, H., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Hunter, D. J., Hankinson, S. E., Cox, D. G., Hall, P., Wedren, S., Liu, J., Low, Y. L., Bogdanova, N., Schürmann, P., Dörk, T., Tollenaar, R. A. E. M., Jacobi, C. E., Devilee, P., Klijn, J. G. M., Sigurdson, A. J., Doody, M. M., Alexander, B. H., Zhang, J., Cox, A., Brock, I. W., MacPherson, G., Reed, M. W. R., Couch, F. J., Goode, E. L., Olson, J. E., Meijers-Heijboer, H., Van Den Ouweland, A., Uitterlinden, A., Rivadeneira, F., Milne, R. L., Ribas, G., Gonzalez-Neira, A., Benitez, J., Hopper, J. L., McCredie, M., Southey, M., Giles, G., Schroen, C., Justenhoven, C., Brauch, H., Hamann, U., Ko, Y. D., Spurdle, A. B., Beesley, J., Chen, X., Mannermaa, A., Kosma, V. M., Kataja, V., Hartikainen, J., Day, N. E., Cox, D. R., Ponder, B. A. J., Luccarini, C., Conroy, D., Shah, M., Munday, H., Jordan, C., Perkins, B., West, J., Redman, K., Driver, K., Aghmesheh, M., Amor, D., Andrews, L., Antill, Y., Armes, J., Armitage, S., Arnold, L., Balleine, R., Begley, G., Beilby, J., Bennett, I., Bennett, B., Berry, G., Blackburn, A., Brennan, M., Brown, M., Buckley, M., Burke, J., Butow, P., Byron, K., Callen, D., Campbell, I., Clarke, C., Colley, A., Cotton, D., Cui, J., Culling, B., Cummings, M., Dawson, S. J., Dixon, J., Dobrovic, A., Dudding, T., Edkins, T., Eisenbruch, M., Farshid, G., Fawcett, S., Field, M., Firgaira, F., Fleming, J., Forbes, J., Friedlander, M., Gaff, C., Gardner, M., Gattas, M., George, P., Gill, G., Goldblatt, J., Greening, S., Grist, S., Haan, E., Harris, M., Hart, S., Hayward, N., Hopper, J., Humphrey, E., Jenkins, M., Jones, A., Kefford, R., Kirk, J., Kollias, J., Kovalenko, S., Lakhani, S., Leary, J., Lim, J., Lindeman, G., Lipton, L., Lobb, L., Maclurcan, M., Mann, G., Marsh, D., McKay, M., Anne McLachlan, S., Meiser, B., Milne, R., Mitchell, G., Newman, B., O'Loughlin, I., Osborne, R., Peters, L., Phillips, K., Price, M., Reeve, J., Reeve, T., Richards, R., Rinehart, G., Robinson, B., Rudzki, B., Salisbury, E., Sambrook, J., Saunders, C., Scott, C., Scott, E., Scott, R., Seshadri, R., Shelling, A., Spurdle, A., Suthers, G., Taylor, D., Tennant, C., Thorne, H., Townshend, S., Tucker, K., Tyler, J., Venter, D., Visvader, J., Walpole, I., Ward, R., Waring, P., Warner, B., Warren, G., Watson, E., Williams, R., Wilson, J., Winship, I., Young, M. A., Bowtell, D., Bowtell, D., Green, A., DeFazio, A., Gertig, D. & Webb, P., Jun 28 2007, In: Nature. 447, 7148, p. 1087-1093 7 p.

    Research output: Contribution to journalArticlepeer-review

    1826 Scopus citations
  • Identification of BRCA1 missense substitutions that confer partial functional activity: Potential moderate risk variants?

    Lovelock, P. K., Spurdle, A. B., Mok, M. T. S., Farrugia, D. J., Lakhani, S. R., Healey, S., Arnold, S., Buchanan, D., Investigators, K. C. F., Couch, F. J., Henderson, B. R., Goldgar, D. E., Tavtigian, S. V., Chenevix-Trench, G. & Brown, M. A., Nov 26 2007, In: Breast Cancer Research. 9, 6, R82.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    42 Scopus citations
  • Molecular basis for estrogen receptor α deficiency in BRCA1-linked breast cancer

    Hosey, A. M., Gorski, J. J., Murray, M. M., Quinn, J. E., Chung, W. Y., Stewart, G. E., James, C. R., Farragher, S. M., Mulligan, J. M., Scott, A. N., Dervan, P. A., Johnston, P. G., Couch, F. J., Daly, P. A., Kay, E., McCann, A., Mullan, P. B. & Harkin, D. P., Nov 2007, In: Journal of the National Cancer Institute. 99, 22, p. 1683-1694 12 p.

    Research output: Contribution to journalArticlepeer-review

    162 Scopus citations
  • RAD51 135G→C modifies breast cancer risk among BRCA2 mutation carriers: Results from a combined analysis of 19 studies

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    Research output: Contribution to journalArticlepeer-review

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