Fergus J Couch

Fergus J Couch, PhD

Chair, Division of Experimental Pathology

1991 …2022

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  • 2011

    A common variant at the TERT-CLPTM1L locus is associated with estrogen receptorĝ€"negative breast cancer

    Haiman, C. A., Chen, G. K., Vachon, C. M., Canzian, F., Dunning, A., Millikan, R. C., Wang, X., Ademuyiwa, F., Ahmed, S., Ambrosone, C. B., Baglietto, L., Balleine, R., Bandera, E. V., Beckmann, M. W., Berg, C. D., Bernstein, L., Blomqvist, C., Blot, W. J., Brauch, H., Buring, J. E., & 110 othersCarey, L. A., Carpenter, J. E., Chang-Claude, J., Chanock, S. J., Chasman, D. I., Clarke, C. L., Cox, A., Cross, S. S., Deming, S. L., Diasio, R. B., Dimopoulos, A. M., Driver, W. R., Dünnebier, T., Durcan, L., Eccles, D., Edlund, C. K., Ekici, A. B., Fasching, P. A., Feigelson, H. S., Flesch-Janys, D., Fostira, F., Försti, A., Fountzilas, G., Gerty, S. M., Giles, G. G., Godwin, A. K., Goodfellow, P., Graham, N., Greco, D., Hamann, U., Hankinson, S. E., Hartmann, A., Hein, R., Heinz, J., Holbrook, A., Hoover, R. N., Hu, J. J., Hunter, D. J., Ingles, S. A., Irwanto, A., Ivanovich, J., John, E. M., Johnson, N., Jukkola-Vuorinen, A., Kaaks, R., Ko, Y. D., Kolonel, L. N., Konstantopoulou, I., Kosma, V. M., Kulkarni, S., Lambrechts, D., Lee, A. M., Marchand, L. L., Lesnick, T., Liu, J., Lindstrom, S., Mannermaa, A., Margolin, S., Martin, N. G., Miron, P., Montgomery, G. W., Nevanlinna, H., Nickels, S., Nyante, S., Olswold, C., Palmer, J., Pathak, H., Pectasides, D., Perou, C. M., Peto, J., Pharoah, P. D. P., Pooler, L. C., Press, M. F., Pylkäs, K., Rebbeck, T. R., Rodriguez-Gil, J. L., Rosenberg, L., Ross, E., Rüdiger, T., Silva, I. D. S., Sawyer, E., Schmidt, M. K., Schulz-Wendtland, R., Schumacher, F., Severi, G., Sheng, X., Signorello, L. B., Sinn, H. P., Stevens, K. N., Southey, M. C., Tapper, W. J., Tomlinson, I., Hogervorst, F. B. L., Wauters, E., Weaver, J., Wildiers, H., Winqvist, R., Berg, D. V. D., Wan, P., Xia, L. Y., Yannoukakos, D., Zheng, W., Ziegler, R. G., Siddiq, A., Slager, S. L., Stram, D. O., Easton, D., Kraft, P., Henderson, B. E. & Couch, F. J., Dec 2011, In: Nature Genetics. 43, 12, p. 1210-1214 5 p.

    Research output: Contribution to journalArticlepeer-review

    231 Scopus citations
  • A computational method to classify variants of uncertain significance using functional assay data with application to BRCA1

    Iversen, E. S., Couch, F. J., Goldgar, D. E., Tavtigian, S. V. & Monteiro, A. N. A., Jun 2011, In: Cancer Epidemiology Biomarkers and Prevention. 20, 6, p. 1078-1088 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    37 Scopus citations
  • Assessment of hepatocyte growth factor in ovarian cancer mortality

    Goode, E. L., Chenevix-Trench, G., Hartmann, L. C., Fridley, B. L., Kalli, K. R., Vierkant, R. A., Larson, M. C., White, K. L., Keeney, G. L., Oberg, T. N., Cunningham, J. M., Beesley, J., Johnatty, S. E., Chen, X., Goodman, K. E., Armasu, S. M., Rider, D. N., Sicotte, H., Schmidt, M. M., Elliott, E. A., & 22 othersHøgdall, E., Kjær, S. K., Fasching, P. A., Ekici, A. B., Lambrechts, D., Despierre, E., Høgdall, C., Lundvall, L., Karlan, B. Y., Gross, J., Brown, R., Chien, J., Duggan, D. J., Tsai, Y. Y., Phelan, C. M., Kelemen, L. E., Peethambaram, P. P., Schildkraut, J. M., Shridhar, V., Sutphen, R., Couch, F. J. & Sellers, T. A., Aug 2011, In: Cancer Epidemiology Biomarkers and Prevention. 20, 8, p. 1638-1648 11 p.

    Research output: Contribution to journalArticlepeer-review

    30 Scopus citations
  • Associations of breast cancer risk factors with tumor subtypes: A pooled analysis from the breast cancer association consortium studies

    Yang, X. R., Chang-Claude, J., Goode, E. L., Couch, F. J., Nevanlinna, H., Milne, R. L., Gaudet, M., Schmidt, M. K., Broeks, A., Cox, A., Fasching, P. A., Hein, R., Spurdle, A. B., Blows, F., Driver, K., Flesch-Janys, D., Heinz, J., Sinn, P., Vrieling, A., Heikkinen, T., & 154 othersAittomäki, K., Heikkilä, P., Blomqvist, C., Lissowska, J., Peplonska, B., Chanock, S., Figueroa, J., Brinton, L., Hall, P., Czene, K., Humphreys, K., Darabi, H., Liu, J., Van 'T Veer, L. J., Van Leeuwen, F. E., Andrulis, I. L., Glendon, G., Knight, J. A., Mulligan, A. M., O'Malley, F. P., Weerasooriya, N., John, E. M., Beckmann, M. W., Hartmann, A., Weihbrecht, S. B., Wachter, D. L., Jud, S. M., Loehberg, C. R., Baglietto, L., English, D. R., Giles, G. G., McLean, C. A., Severi, G., Lambrechts, D., Vandorpe, T., Weltens, C., Paridaens, R., Smeets, A., Neven, P., Wildiers, H., Wang, X., Olson, J. E., Cafourek, V., Fredericksen, Z., Kosel, M., Vachon, C., Cramp, H. E., Connley, D., Cross, S. S., Balasubramanian, S. P., Reed, M. W. R., Dörk, T., Bremer, M., Meyer, A., Karstens, J. H., Ay, A., Park-Simon, T. W., Hillemanns, P., Arias Pérez, J. I., Rodríguez, P. M., Zamora, P., Benítez, J., Ko, Y. D., Fischer, H. P., Hamann, U., Pesch, B., Brüning, T., Justenhoven, C., Brauch, H., Eccles, D. M., Tapper, W. J., Gerty, S. M., Sawyer, E. J., Tomlinson, I. P., Jones, A., Kerin, M., Miller, N., McInerney, N., Anton-Culver, H., Ziogas, A., Shen, C. Y., Hsiung, C. N., Wu, P. E., Yang, S. L., Yu, J. C., Chen, S. T., Hsu, G. C., Haiman, C. A., Henderson, B. E., Le Marchand, L., Kolonel, L. N., Lindblom, A., Margolin, S., Jakubowska, A., Lubiński, J., Huzarski, T., Byrski, T., Górski, B., Gronwald, J., Hooning, M. J., Hollestelle, A., Van Den Ouweland, A. M. W., Jager, A., Kriege, M., Tilanus-Linthorst, M. M. A., Collée, M., Wang-Gohrke, S., Pylkäs, K., Jukkola-Vuorinen, A., Mononen, K., Grip, M., Hirvikoski, P., Winqvist, R., Mannermaa, A., Kosma, V. M., Kauppinen, J., Kataja, V., Auvinen, P., Soini, Y., Sironen, R., Bojesen, S. E., Dynnes Ørsted, D., Kaur-Knudsen, D., Flyger, H., Nordestgaard, B. G., Holland, H., Chenevix-Trench, G., Manoukian, S., Barile, M., Radice, P., Hankinson, S. E., Hunter, D. J., Tamimi, R., Sangrajrang, S., Brennan, P., McKay, J., Odefrey, F., Gaborieau, V., Devilee, P., Huijts, P. E. A., Tollenaar, R., Seynaeve, C., Dite, G. S., Apicella, C., Hopper, J. L., Hammet, F., Tsimiklis, H., Smith, L. D., Southey, M. C., Humphreys, M. K., Easton, D., Pharoah, P., Sherman, M. E. & Garcia-Closas, M., Feb 2 2011, In: Journal of the National Cancer Institute. 103, 3, p. 250-263 14 p.

    Research output: Contribution to journalArticlepeer-review

    468 Scopus citations
  • Associations of common variants at 1p11.2 and 14q24.1 (RAD51l1) with breast cancer risk and heterogeneity by tumor subtype: Findings from the Breast Cancer Association Consortium

    Figueroa, J. D., Garcia-Closas, M., Humphreys, M., Platte, R., Hopper, J. L., Southey, M. C., Apicella, C., Hammet, F., Schmidt, M. K., Broeks, A., Tollenaar, R. A. E. M., Van't Veer, L. J., Fasching, P. A., Beckmann, M. W., Ekici, A. B., Strick, R., Peto, J., Silva, I. D. S., Fletcher, O., Johnson, N., & 137 othersSawyer, E., Tomlinson, I., Kerin, M., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Bojesen, S., Flyger, H., Nordestgaard, B. G., Beni´tez, J., Milne, R. L., Arias, J. I., Zamora, M. P., Brenner, H., Mu¨ller, H., Arndt, V., Rahman, N., Turnbull, C., Seal, S., Renwick, A., Brauch, H., Justenhoven, C., Bru¨ning, T., Ko, Y. D., Baisch, C., Fischer, H. P., Hamann, U., Pesch, B., Rabstein, S., Harth, V., Chang-Claude, J., Hein, R., Wang-Gohrke, S., Do¨rk, T., Schu¨rmann, P., Bremer, M., Hillemanns, P., Nevanlinna, H., Heikkinen, T., Aittoma¨ki, K., Blomqvist, C., Bogdanova, N., Antonenkova, N., Rogov, Y. I., Karstens, J. H., Bermisheva, M., Prokofieva, D., Gantcev, S. H., Khusnutdinova, E., Lindblom, A., Margolin, S., Chenevix-Trench, G., Beesley, J., Chen, X., Bowtell, D., deFazio, A., Gertig, D., Green, A., Webb, P. M., Mannermaa, A., Kosma, V. M., Soini, Y., Kataja, V., Lambrechts, D., Yesilyurt, B. T., Chrisiaens, M. R., Peeters, S., Radice, P., Peterlongo, P., Manoukian, S., Barile, M., Couch, F., Lee, A. M., Diasio, R., Wang, X., Giles, G. G., Severi, G., Baglietto, L., Maclean, C., Offit, K., Robson, M., Joseph, V., Gaudet, M., John, E. M., Winqvist, R., Pylka¨s, K., Jukkola-Vuorinen, A., Grip, M., Andrulis, I., Knight, J. A., Mulligan, A. M., O'Malley, F. P., Brinton, L. A., Sherman, M. E., Lissowska, J., Chanock, S. J., Hooning, M., Martens, J. W. M., van den Ouweland, A. M. W., Colle´e, J. M., Hall, P., Czene, K., Cox, A., Brock, I. W., Reed, M. W. R., Cross, S. S., Pharoah, P., Dunning, A. M., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Sangrajrang, S., Gaborieau, V., Brennan, P., McKay, J., Shen, C. Y., Ding, S. L., Hsu, H. M., Yu, J. C., Anton-Culver, H., Ziogas, A., Ashworth, A., Swerdlow, A., Jones, M., Orr, N., Trentham-Dietz, A., Egan, K., Newcomb, P., Titus-Ernstoff, L., Easton, D. & Spurdle, A. B., Dec 1 2011, In: Human molecular genetics. 20, 23, p. 4693-4706 14 p.

    Research output: Contribution to journalArticlepeer-review

    61 Scopus citations
  • Centrosome-related genes, genetic variation, and risk of breast cancer

    Olson, J. E., Wang, X., Pankratz, V. S., Fredericksen, Z. S., Vachon, C. M., Vierkant, R. A., Cerhan, J. R. & Couch, F. J., Jan 2011, In: Breast Cancer Research and Treatment. 125, 1, p. 221-228 8 p.

    Research output: Contribution to journalArticlepeer-review

    34 Scopus citations
  • Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

    Antoniou, A. C., Kartsonaki, C., Sinilnikova, O. M., Soucy, P., McGuffog, L., Healey, S., Lee, A., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Cattaneo, E., Barile, M., Pensotti, V., Pasini, B., Dolcetti, R., Giannini, G., Putignano, A. L., Varesco, L., Radice, P., & 282 othersMai, P. L., Greene, M. H., Andrulis, I. L., Glendon, G., Ozcelik, H., Thomassen, M., Gerdes, A. M., Kruse, T. A., Jensen, U. B., Crüger, D. G., Caligo, M. A., Laitman, Y., Milgrom, R., Kaufman, B., Paluch-Shimon, S., Friedman, E., Loman, N., Harbst, K., Lindblom, A., Arver, B., Ehrencrona, H., Melin, B., Nathanson, K. L., Domchek, S. M., Rebbeck, T., Jakubowska, A., Lubinski, J., Gronwald, J., Huzarski, T., Byrski, T., Cybulski, C., Gorski, B., Osorio, A., Cajal, T. R., Fostira, F., Andrés, R., Benitez, J., Hamann, U., Hogervorst, F. B., Rookus, M. A., Hooning, M. J., Nelen, M. R., van der Luijt, R. B., van Os, T. A. M., van Asperen, C. J., Devilee, P., Meijers-Heijboer, H. E. J., Garcia, E. B. G., Peock, S., Cook, M., Frost, D., Platte, R., Leyland, J., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Adlard, J., Davidson, R., Eccles, D., Ong, K. R., Cook, J., Douglas, F., Paterson, J., Kennedy, M. J., Miedzybrodzka, Z., Godwin, A., Stoppa-Lyonnet, D., Buecher, B., Belotti, M., Tirapo, C., Mazoyer, S., Barjhoux, L., Lasset, C., Leroux, D., Faivre, L., Bronner, M., Prieur, F., Nogues, C., Rouleau, E., Pujol, P., Coupier, I., Frénay, M., Hopper, J. L., Daly, M. B., Terry, M. B., John, E. M., Buys, S. S., Yassin, Y., Miron, A., Goldgar, D., Singer, C. F., Tea, M. K., Pfeiler, G., Dressler, A. C., Hansen, T. V. O., Jønson, L., Ejlertsen, B., Barkardottir, R. B., Kirchhoff, T., Offit, K., Piedmonte, M., Rodriguez, G., Small, L., Boggess, J., Blank, S., Basil, J., Azodi, M., Toland, A. E., Montagna, M., Tognazzo, S., Agata, S., Imyanitov, E., Janavicius, R., Lazaro, C., Blanco, I., Pharoah, P. D. P., Sucheston, L., Karlan, B. Y., Walsh, C. S., Olah, E., Bozsik, A., Teo, S. H., Seldon, J. L., Beattie, M. S., van Rensburg, E. J., Sluiter, M. D., Diez, O., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Meindl, A., Ruehl, I., Varon-Mateeva, R., Kast, K., Deissler, H., Niederacher, D., Arnold, N., Gadzicki, D., Schönbuchner, I., Caldes, T., de la Hoya, M., Nevanlinna, H., Aittomäki, K., Dumont, M., Chiquette, J., Tischkowitz, M., Chen, X., Beesley, J., Spurdle, A. B., Neuhausen, S. L., Ding, Y. C., Fredericksen, Z., Wang, X., Pankratz, V. S., Couch, F., Simard, J., Easton, D. F., Chenevix-Trench, G., Karlsson, P., Nordling, M., Bergman, A., Einbeigi, Z., Stenmark-Askmalm, M., Liedgren, S., Borg, A., Olsson, H., Kristoffersson, U., Jernström, H., Henriksson, K., von Wachenfeldt, A., Liljegren, A., Barbany-Bustinza, G., Rantala, J., Grönberg, H., Stattin, E. L., Emanuelsson, M., Brandell, R. R., Dahl, N., Verhoef, S., Verheus, M., Veer, L. J. V. T., van Leeuwen, F. E., Collée, M., van den Ouweland, A. M. W., Jager, A., Tilanus-Linthorst, M. M. A., Seynaeve, C., Wijnen, J. T., Vreeswijk, M. P., Tollenaar, R. A., Ligtenberg, M. J., Hoogerbrugge, N., Ausems, M. G., Aalfs, C. M., van Os, T. A. M., Gille, J. J. P., Waisfisz, Q., Gomez-Garcia, E. B., van Roozendaal, C. E., Blok, M. J., Caanen, B., Oosterwijk, J. C., van der Hout, A. H., Mourits, M. J., Vasen, H. F., Gregory, H., Morrison, P., Jeffers, L., Cole, T., McKeown, C., Hoffman, J., Donaldson, A., Downing, S., Taylor, A., Murray, A., Rogers, M. T., McCann, E., Barton, D., Porteous, M., Drummond, S., Brewer, C., Kivuva, E., Searle, A., Goodman, S., Hill, K., Murday, V., Bradshaw, N., Snadden, L., Longmuir, M., Watt, C., Gibson, S., Haque, E., Tobias, E., Duncan, A., Jacobs, C., Langman, C., Whaite, A., Dorkins, H., Barwell, J., Chu, C., Miller, J., Ellis, I., Houghton, C., Taylor, J., Side, L., Male, A., Berlin, C., Eason, J., Collier, R., Claber, O., Jobson, I., Walker, L., McLeod, D., Halliday, D., Durell, S., Stayner, B., Shanley, S., Rahman, N., Houlston, R., Bancroft, E., D'Mello, L., Page, E., Ardern-Jones, A., Kohut, K., Wiggins, J., Castro, E., Mitra, A., Robertson, L., Quarrell, O., Bardsley, C., Hodgson, S., Goff, S., Brice, G., Winchester, L., Eddy, C., Tripathi, V., Attard, V., Lucassen, A., Crawford, G., McBride, D. & Smalley, S., Aug 1 2011, In: Human molecular genetics. 20, 16, p. 3304-3321 18 p.

    Research output: Contribution to journalArticlepeer-review

    56 Scopus citations
  • Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

    Mulligan, A. M., Couch, F. J., Barrowdale, D., Domchek, S. M., Eccles, D., Nevanlinna, H., Ramus, S. J., Robson, M., Sherman, M., Spurdle, A. B., Wappenschmidt, B., Lee, A., McGuffog, L., Healey, S., Sinilnikova, O. M., Janavicius, R., Hansen, T. V., Nielsen, F. C., Ejlertsen, B., Osorio, A., & 162 othersMuñoz-Repeto, I., Durán, M., Godino, J., Pertesi, M., Benítez, J., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Cattaneo, E., Bonanni, B., Viel, A., Pasini, B., Papi, L., Ottini, L., Savarese, A., Bernard, L., Radice, P., Hamann, U., Verheus, M., Meijers-Heijboer, H. E. J., Wijnen, J., Gómez García, E. B., Nelen, M. R., Kets, C. M., Seynaeve, C., Tilanus-Linthorst, M. M. A., van der Luijt, R. B., Os, T. V., Rookus, M., Frost, D., Jones, J. L., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Adlard, J., Davidson, R., Cook, J., Donaldson, A., Dorkins, H., Gregory, H., Eason, J., Houghton, C., Barwell, J., Side, L. E., McCann, E., Murray, A., Peock, S., Godwin, A. K., Schmutzler, R. K., Rhiem, K., Engel, C., Meindl, A., Ruehl, I., Arnold, N., Niederacher, D., Sutter, C., Deissler, H., Gadzicki, D., Kast, K., Preisler-Adams, S., Varon-Mateeva, R., Schoenbuchner, I., Fiebig, B., Heinritz, W., Schäfer, D., Gevensleben, H., Caux-Moncoutier, V., Fassy-Colcombet, M., Cornelis, F., Mazoyer, S., Léoné, M., Boutry-Kryza, N., Hardouin, A., Berthet, P., Muller, D., Fricker, J. P., Mortemousque, I., Pujol, P., Coupier, I., Lebrun, M., Kientz, C., Longy, M., Sevenet, N., Stoppa-Lyonnet, D., Isaacs, C., Caldes, T., de la Hoya, M., Heikkinen, T., Aittomäki, K., Blanco, I., Lazaro, C., Barkardottir, R. B., Soucy, P., Dumont, M., Simard, J., Montagna, M., Tognazzo, S., D'Andrea, E., Fox, S., Yan, M., Rebbeck, T., Olopade, O. I., Weitzel, J. N., Lynch, H. T., Ganz, P. A., Tomlinson, G. E., Wang, X., Fredericksen, Z., Pankratz, V. S., Lindor, N. M., Szabo, C., Offit, K., Sakr, R., Gaudet, M., Bhatia, J., Kauff, N., Singer, C. F., Tea, M. K., gschwantler-kaulich, D., Fink-Retter, A., Mai, P. L., Greene, M. H., Imyanitov, E., O'Malley, F. P., Ozcelik, H., Glendon, G., Toland, A. E., Gerdes, A. M., Thomassen, M., Kruse, T. A., Jensen, U. B., Skytte, A. B., Caligo, M. A., Soller, M., Henriksson, K., Wachenfeldt, V. A., Arver, B., Stenmark-Askmalm, M., Karlsson, P., Ding, Y. C., Neuhausen, S. L., Beattie, M., Pharoah, P. D. P., Moysich, K. B., Nathanson, K. L., Karlan, B. Y., Gross, J., John, E. M., Daly, M. B., Buys, S. M., Southey, M. C., Hopper, J. L., Terry, M. B., Chung, W., Miron, A. F., Goldgar, D., Chenevix-Trench, G., Easton, D. F., Andrulis, I. L. & Antoniou, A. C., Nov 2 2011, In: Breast Cancer Research. 13, 6, R110.

    Research output: Contribution to journalArticlepeer-review

    53 Scopus citations
  • Common breast cancer susceptibility loci are associated with triple-negative breast cancer

    Stevens, K. N., Vachon, C. M., Lee, A. M., Slager, S., Lesnick, T., Olswold, C., Fasching, P. A., Miron, P., Eccles, D., Carpenter, J. E., Godwin, A. K., Ambrosone, C., Winqvist, R., Brauch, H., Schmidt, M. K., Cox, A., Cross, S. S., Sawyer, E., Hartmann, A., Beckmann, M. W., & 63 othersSchulz-Wendtland, R., Ekici, A. B., Tapper, W. J., Gerty, S. M., Durcan, L., Graham, N., Hein, R., Nickels, S., Flesch-Janys, D., Heinz, J., Sinn, H. P., Konstantopoulou, I., Fostira, F., Pectasides, D., Dimopoulos, A. M., Fountzilas, G., Clarke, C. L., Balleine, R., Olson, J. E., Fredericksen, Z., Diasio, R. B., Pathak, H., Ross, E., Weaver, J. E., Rüdiger, T., Försti, A., Dünnebier, T., Ademuyiwa, F., Kulkarni, S., Pylkäs, K., Jukkola-Vuorinen, A., Ko, Y. D., Van Limbergen, E., Janssen, H., Peto, J., Fletcher, O., Giles, G. G., Baglietto, L., Verhoef, S., Tomlinson, I., Kosma, V. M., Beesley, J., Greco, D., Blomqvist, C., Irwanto, A., Liu, J., Blows, F. M., Dawson, S. J., Margolin, S., Mannermaa, A., Martin, N. G., Montgomery, G. W., Lambrechts, D., Dos Santos Silva, I., Severi, G., Hamann, U., Pharoah, P., Easton, D. F., Chang-Claude, J., Yannoukakos, D., Nevanlinna, H., Wang, X. & Couch, F. J., Oct 1 2011, In: Cancer research. 71, 19, p. 6240-6249 10 p.

    Research output: Contribution to journalArticlepeer-review

    94 Scopus citations
  • Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers

    Spurdle, A. B., Marquart, L., McGuffog, L., Healey, S., Sinilnikova, O., Wan, F., Chen, X., Beesley, J., Singer, C. F., Dressler, A. C., Gschwantler-Kaulich, D., Blum, J. L., Tung, N., Weitzel, J., Lynch, H., Garber, J., Easton, D. F., Peock, S., Cook, M., Oliver, C. T., & 58 othersFrost, D., Conroy, D., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Davidson, R., Chu, C., Eccles, D., Selkirk, C. G., Daly, M., Isaacs, C., Stoppa-Lyonnet, D., Sinilnikova, O. M., Buecher, B., Belotti, M., Mazoyer, S., Barjhoux, L., Verny-Pierre, C., Lasset, C., Dreyfus, H., Pujol, P., Collonge-Rame, M. A., Rookus, M. A., Verhoef, S., Kriege, M., Hoogerbrugge, N., Ausems, M. G. E. M., Van Os, T. A., Wijnen, J., Devilee, P., Meijers-Heijboer, H. E. J., Blok, M. J., Heikkinen, T., Nevanlinna, H., Jakubowska, A., Lubiński, J., Huzarski, T., Byrski, T., Durocher, F., Couch, F. J., Lindor, N. M., Wang, X., Thomassen, M., Domchek, S., Nathanson, K., Caligo, M. A., Jernström, H., Liljegren, A., Ehrencrona, H., Karlsson, P., Ganz, P. A., Olopade, O. I., Tomlinson, G., Neuhausen, S., Antoniou, A. C., Chenevix-Trench, G. & Rebbeck, T. R., May 2011, In: Cancer Epidemiology Biomarkers and Prevention. 20, 5, p. 1032-1038 7 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers

    Cox, D. G., Simard, J., Sinnett, D., Hamdi, Y., Soucy, P., Ouimet, M., Barjhoux, L., Verny-Pierre, C., McGuffog, L., Healey, S., Szabo, C., Greene, M. H., Mai, P. L., Andrulis, I. L., Glendon, G., Selander, T., Weerasooriya, N., Thomassen, M., Gerdes, A. M., Caligo, M. A., & 302 othersFriedman, E., Laitman, Y., Kaufman, B., Paluch, S. S., Borg, Å., Karlsson, P., Askmalm, M. S., Bustinza, G. B., Nathanson, K. L., Domchek, S. M., Rebbeck, T. R., Benítez, J., Hamann, U., Rookus, M. A., van den Ouweland, A. M. W., Ausems, M. G. E. M., Aalfs, C. M., van Asperen, C. J., Devilee, P., Gille, H. J. J. P., Peock, S., Frost, D., Evans, D. G., Eeles, R., Izatt, L., Adlard, L. D., Paterson, J., Eason, J., Godwin, A. K., Remon, M. A., Moncoutier, V., Gauthier-Villars, M., Lasset, C., Giraud, S., Hardouin, A., Berthet, P., Sobol, H., Eisinger, F., de Paillerets, B. B., Caron, O., Delnatte, C., Goldgar, D., Miron, A., Ozcelik, H., Buys, S., Southey, M. C., Terry, M. B., Singer, C. F., Dressler, A. C., Tea, M. K., Hansen, T. V. O., Johannsson, O., Piedmonte, M., Rodriguez, G. C., Basil, J. B., Blank, S., Toland, A. E., Montagna, M., Isaacs, C., Blanco, I., Gayther, S. A., Moysich, K. B., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Niederacher, D., Sutter, C., Gadzicki, D., Fiebig, B., Caldes, T., Laframboise, R., Nevanlinna, H., Chen, X., Beesley, J., Spurdle, A. B., Neuhausen, S. L., Ding, Y. C., Couch, F. J., Wang, X., Peterlongo, P., Manoukian, S., Bernard, L., Radice, P., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C., Stoppa-Lyonnet, D., Mazoyer, S., Sinilnikova, O. M., Nordling, M., Bergman, A., Einbeigi, Z., Stenmark-Askmalm, M., Liedgren, S., Borg, Å., Loman, N., Olsson, H., Kristoffersson, U., Soller, M., Jernström, H., Harbst, K., Henriksson, K., Lindblom, A., Arver, B., von Wachenfeldt, A., Liljegren, A., Barbany-Bustinza, G., Rantala, J., Melin, B., Grönberg, H., Stattin, E. L., Emanuelsson, M., Ehrencrona, H., Brandell, R. R., Dahl, N., Hogervorst, F. B. L., Verhoef, S., Verheus, M., van't Veer, L. J., van Leeuwen, F. E., Rookus, M. A., Collée, M., Jager, A., Hooning, M. J., Tilanus-Linthorst, M. M. A., Seynaeve, C., van Asperen, C. J., Wijnen, J. T., Vreeswijk, M. P., Tollenaar, R. A., Ligtenberg, M. J., Hoogerbrugge, N., Ausems, M. G., van der Luijt, R. B., Aalfs, C. M., van Os, T. A., Gille, J. J. P., Waisfisz, Q., Meijers-Heijboer, H. E. J., Gomez-Garcia, E. B., van Roozendaal, C. E., Blok, M. J., Caanen, B., Oosterwijk, J. C., van der Hout, A. H., Mourits, M. J., Vasen, H. F., Peock, S., Cook, M., Frost, D., Platte, R., Miedzybrodzka, Z., Gregory, H., Morrison, P., Jeffers, L., Cole, T., Ong, K. R., Hoffman, J., Donaldson, A., James, M., Paterson, J., Downing, S., Taylor, A., Murray, A., Rogers, M. T., McCann, E., Kennedy, M. J., Barton, D., Porteous, M., Drummond, S., Brewer, C., Kivuva, E., Searle, A., Goodman, S., Hill, K., Davidson, R., Murday, V., Bradshaw, N., Snadden, L., Longmuir, M., Watt, C., Gibson, S., Haque, E., Tobias, E., Duncan, A., Izatt, L., Jacobs, C., Langman, C., Whaite, A., Dorkins, H., Barwell, J., Adlard, J., Chu, C., Miller, J., Ellis, I., Houghton, C., Lalloo, F., Taylor, J., Side, L., Male, A., Berlin, C., Eason, J., Collier, R., Douglas, F., Claber, O., Jobson, I., Walker, L., McLeod, D., Halliday, D., Durell, S., Stayner, B., Eeles, R., Shanley, S., Rahman, N., Houlston, R., Bancroft, E., D'Mello, L., Page, E., Ardern-Jones, A., Kohut, K., Wiggins, J., Castro, E., Mitra, A., Robertson, L., Cook, J., Quarrell, O., Bardsley, C., Hodgson, S., Goff, S., Brice, G., Winchester, L., Eddy, C., Tripathi, V., Attard, V., Eccles, D., Lucassen, A., Crawford, G., McBride, D., Smalley, S., Sinilnikova, O., Barjhoux, L., Verny-Pierre, C., Giraud, S., Léone, M., Mazoyer, S., Stoppa-Lyonnet, D., Gauthier-Villars, M., Buecher, B., Houdayer, C., Moncoutier, V., Belotti, M., Tirapo, C., de Pauw, A., Bressac-de-Paillerets, B., Remenieras, A., Byrde, V., Caron, O., Lenoir, G., Bignon, Y. J., Uhrhammer, N., Bonadona, V., Hardouin, A., Berthet, P., Sobol, H., Bourdon, V., Noguchi, T., Eisinger, F., Coulet, F., Colas, C., Soubrier, F., Coupier, I., Pujol, P., Peyrat, J. P., Fournier, J., Révillion, F., Vennin, P., Adenis, C., Rouleau, E., Lidereau, R., Demange, L., Nogues, C., Muller, D., Fricker, J. P., Longy, M., Sevenet, N., Toulas, C., Guimbaud, R., Gladieff, L., Feillel, V., Leroux, D., Dreyfus, H., Rebischung, C., Coron, F., Faivre, L., Prieur, F., Lebrun, M., Ferrer, S. F., Frénay, M. & Vénat-Bouvet, L., Dec 1 2011, In: Human molecular genetics. 20, 23, p. 4732-4747 16 p.

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations
  • Confirmation of 5p12 as a susceptibility locus for progesterone-receptor- positive, lower grade breast cancer

    Milne, R. L., Goode, E. L., García-Closas, M., Couch, F. J., Severi, G., Hein, R., Fredericksen, Z., Malats, N., Zamora, M. P., Pérez, J. I. A., Benítez, J., Dörk, T., Schürmann, P., Karstens, J. H., Hillemanns, P., Cox, A., Brock, I. W., Elliot, G., Cross, S. S., Seal, S., & 123 othersTurnbull, C., Renwick, A., Rahman, N., Shen, C. Y., Yu, J. C., Huang, C. S., Hou, M. F., Nordestgaard, B. G., Bojesen, S. E., Lanng, C., Alnæs, G. G., Kristensen, V., Børrensen-Dale, A. L., Hopper, J. L., Dite, G. S., Apicella, C., Southey, M. C., Lambrechts, D., Yesilyurt, B. T., Floris, G., Leunen, K., Sangrajrang, S., Gaborieau, V., Brennan, P., McKay, J., Chang-Claude, J., Wang-Gohrke, S., Radice, P., Peterlongo, P., Manoukian, S., Barile, M., Giles, G. G., Baglietto, L., John, E. M., Miron, A., Chanock, S. J., Lissowska, J., Sherman, M. E., Figueroa, J. D., Bogdanova, N. V., Antonenkova, N. N., Zalutsky, I. V., Rogov, Y. I., Fasching, P. A., Bayer, C. M., Ekici, A. B., Beckmann, M. W., Brenner, H., Müller, H., Arndt, V., Stegmaier, C., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Mannermaa, A., Kataja, V., Kosma, V. M., Hartikainen, J. M., Meindl, A., Heil, J., Bartram, C. R., Schmutzler, R. K., Thomas, G. D., Hoover, R. N., Fletcher, O., Gibson, L. J., Dos Santos Silva, I., Peto, J., Nickels, S., Flesch-Janys, D., Anton-Culver, H., Ziogas, A., Sawyer, E., Tomlinson, I., Kerin, M., Miller, N., Schmidt, M. K., Broeks, A., Van't Veer, L. J., Tollenaar, R. A. E. M., Pharoah, P. D. P., Dunning, A. M., Pooley, K. A., Marme, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Hunter, D. J., Hankinson, S. E., Kraft, P., Lindstrom, S., Chen, X., Beesley, J., Hamann, U., Harth, V., Justenhoven, C., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Hooning, M., Hollestelle, A., Oldenburg, R. A., Tilanus-Linthorst, M., Khusnutdinova, E., Bermisheva, M., Prokofieva, D., Farahtdinova, A., Olson, J. E., Wang, X., Humphreys, M. K., Wang, Q., Chenevix-Trench, G. & Easton, D. F., Oct 2011, In: Cancer Epidemiology Biomarkers and Prevention. 20, 10, p. 2222-2231 10 p.

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations
  • Evaluation of associations between common variation in mitotic regulatory pathways and risk of overall and high grade breast cancer

    Stevens, K. N., Wang, X., Fredericksen, Z., Pankratz, V. S., Cerhan, J., Vachon, C. M., Olson, J. E. & Couch, F. J., Sep 2011, In: Breast Cancer Research and Treatment. 129, 2, p. 617-622 6 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2

    Osorio, A., Milne, R. L., Alonso, R., Pita, G., Peterlongo, P., Teulé, A., Nathanson, K. L., Domchek, S. M., Rebbeck, T., Lasa, A., Konstantopoulou, I., Hogervorst, F. B., Verhoef, S., Van Dooren, M. F., Jager, A., Ausems, M. G. E. M., Aalfs, C. M., Van Asperen, C. J., Vreeswijk, M., Waisfisz, Q., & 52 othersVan Roozendaal, C. E., Ligtenberg, M. J., Easton, D. F., Peock, S., Cook, M., Oliver, C. T., Frost, D., Curzon, B., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Davidson, R., Adlard, J., Eccles, D., Ong, K. R., Douglas, F., Downing, S., Brewer, C., Walker, L., Nevanlinna, H., Aittomäki, K., Couch, F. J., Fredericksen, Z., Lindor, N. M., Godwin, A., Isaacs, C., Caligo, M. A., Loman, N., Jernström, H., Barbany-Bustinza, G., Liljegren, A., Ehrencrona, H., Stenmark-Askmalm, M., Feliubadaló, L., Manoukian, S., Peissel, B., Zaffaroni, D., Bonanni, B., Fortuzzi, S., Johannsson, O. T., Chenevix-Trench, G., Chen, X. C., Beesley, J., Spurdle, A. B., Sinilnikova, O. M., Healey, S., McGuffog, L., Antoniou, A. C., Brunet, J., Radice, P. & Benítez, J., Apr 12 2011, In: British journal of cancer. 104, 8, p. 1356-1361 6 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk

    Stevens, K. N., Garcia-Closas, M., Fredericksen, Z., Kosel, M., Pankratz, V. S., Hopper, J. L., Dite, G. S., Apicella, C., Southey, M. C., Schmidt, M. K., Broeks, A., Van T Veer, L. J., Tollenaar, R. A. E. M., Fasching, P. A., Beckmann, M. W., Hein, A., Ekici, A. B., Johnson, N., Peto, J., Dos Santos Silva, I., & 81 othersGibson, L., Sawyer, E., Tomlinson, I., Kerin, M. J., Chanock, S., Lissowska, J., Hunter, D. J., Hoover, R. N., Thomas, G. D., Milne, R. L., Pérez, J. A., González-Neira, A., Benítez, J., Burwinkel, B., Meindl, A., Schmutzler, R. K., Bartrar, C. R., Hamann, U., Ko, Y. D., Brüning, T., Chang-Claude, J., Hein, R., Wang-Gohrke, S., Dörk, T., Schürmann, P., Bremer, M., Hillemanns, P., Bogdanova, N., Zalutsky, J. V., Rogov, Y. I., Antonenkova, N., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V. M., Hartikainen, J., Chenevix-Trench, G., Chen, X., Peterlongo, P., Bonanni, B., Bernard, L., Manoukian, S., Wang, X., Cerhan, J., Vachon, C. M., Olson, J., Giles, G. G., Baglietto, L., McLean, C. A., Severi, G., John, E. M., Miron, A., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Andrulis, I., Knight, J. A., Glendon, G., Mulligan, A. M., Cox, A., Brock, I. W., Elliott, G., Cross, S. S., Pharoah, P. P., Dunning, A. M., Pooley, K. A., Humphreys, M. K., Wang, J., Kang, D., Yoo, K. Y., Noh, D. Y., Sangrajrang, S., Gabrieau, V., Brennan, P., McKay, J., Anton-Culver, H., Ziogas, A., Couch, F. J. & Easton, D. F., Dec 6 2011, In: British journal of cancer. 105, 12, p. 1934-1939 6 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Exploring the link between MORF4L1 and risk of breast cancer

    Martrat, G., Maxwell, C. A., Tominaga, E., Porta-de-la-Riva, M., Bonifaci, N., Gómez-Baldó, L., Bogliolo, M., Lázaro, C., Blanco, I., Brunet, J., Aguilar, H., Fernández-Rodríguez, J., Seal, S., Renwick, A., Rahman, N., Kühl, J., Neveling, K., Schindler, D., Ramírez, M. J., Castellà, M., & 108 othersHernández, G., Easton, D. F., Peock, S., Cook, M., Oliver, C. T., Frost, D., Platte, R., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Chu, C., Davidson, R., Ong, K. R., Cook, J., Douglas, F., Hodgson, S., Brewer, C., Morrison, P. J., Porteous, M., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Roversi, G., Barile, M., Viel, A., Pasini, B., Ottini, L., Putignano, A. L., Savarese, A., Bernard, L., Radice, P., Healey, S., Spurdle, A., Chen, X., Beesley, J., Rookus, M. A., Verhoef, S., Tilanus-Linthorst, M. A., Vreeswijk, M. P., Asperen, C. J., Bodmer, D., Ausems, M. G. E. M., van Os, T. A., Blok, M. J., Meijers-Heijboer, H. E. J., Hogervorst, F. B. L., Goldgar, D. E., Buys, S., John, E. M., Miron, A., Southey, M., Daly, M. B., Harbst, K., Borg, Å., Rantala, J., Barbany-Bustinza, G., Ehrencrona, H., Stenmark-Askmalm, M., Kaufman, B., Laitman, Y., Milgrom, R., Friedman, E., Domchek, S. M., Nathanson, K. L., Rebbeck, T. R., Johannsson, O. T., Couch, F. J., Wang, X., Fredericksen, Z., Cuadras, D., Moreno, V., Pientka, F. K., Depping, R., Caldés, T., Osorio, A., Benítez, J., Bueren, J., Heikkinen, T., Nevanlinna, H., Hamann, U., Torres, D., Caligo, M. A., Godwin, A. K., Imyanitov, E. N., Janavicius, R., Sinilnikova, O. M., Stoppa-Lyonnet, D., Mazoyer, S., Verny-Pierre, C., Castera, L., De Pauw, A., Bignon, Y. J., Uhrhammer, N., Peyrat, J. P., Vennin, P., Ferrer, S. F., Collonge-Rame, M. A., Mortemousque, I., McGuffog, L., Chenevix-Trench, G., Pereira-Smith, O. M., Antoniou, A. C., Cerón, J., Tominaga, K., Surrallés, J. & Pujana, M. A., Apr 5 2011, In: Breast Cancer Research. 13, 2, R40.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers

    Ramus, S. J., Kartsonaki, C., Gayther, S. A., Pharoah, P. D. P., Sinilnikova, O. M., Beesley, J., Chen, X., McGuffog, L., Healey, S., Couch, F. J., Wang, X., Fredericksen, Z., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Roversi, G., Barile, M., Viel, A., Allavena, A., & 133 othersOttini, L., Papi, L., Gismondi, V., Capra, F., Radice, P., Greene, M. H., Mai, P. L., Andrulis, I. L., Glendon, G., Ozcelik, H., Thomassen, M., Gerdes, A. M., Kruse, T. A., Cruger, D., Jensen, U. B., Caligo, M. A., Olsson, H., Kristoffersson, U., Lindblom, A., Arver, B., Karlsson, P., Stenmark Askmalm, M., Borg, A., Neuhausen, S. L., Ding, Y. C., Nathanson, K. L., Domchek, S. M., Jakubowska, A., Lubiński, J., Huzarski, T., Byrski, T., Gronwald, J., Górski, B., Cybulski, C., Dbniak, T., Osorio, A., Durán, M., Tejada, M. I., Benítez, J., Hamann, U., Rookus, M. A., Verhoef, S., Tilanus-Linthorst, M. A., Vreeswijk, M. P., Bodmer, D., Ausems, M. G. E. M., Van Os, T. A., Asperen, C. J., Blok, M. J., Meijers-Heijboer, H. E. J., Peock, S., Cook, M., Oliver, C., Frost, D., Dunning, A. M., Evans, D. G., Eeles, R., Pichert, G., Cole, T., Hodgson, S., Brewer, C., Morrison, P. J., Porteous, M., Kennedy, M. J., Rogers, M. T., Side, L. E., Donaldson, A., Gregory, H., Godwin, A., Stoppa-Lyonnet, D., Moncoutier, V., Castera, L., Mazoyer, S., Barjhoux, L., Bonadona, V., Leroux, D., Faivre, L., Lidereau, R., Nogues, C., Bignon, Y. J., Prieur, F., Collonge-Rame, M. A., Venat-Bouvet, L., Fert-Ferrer, S., Miron, A., Buys, S. S., Hopper, J. L., Daly, M. B., John, E. M., Terry, M. B., Goldgar, D., Hansen, T. V. O., Jønson, L., Ejlertsen, B., Agnarsson, B. A., Offit, K., Kirchhoff, T., Vijai, J., Dutra-Clarke, A. V. C., Przybylo, J. A., Montagna, M., Casella, C., Imyanitov, E. N., Janavicius, R., Blanco, I., Lázaro, C., Moysich, K. B., Karlan, B. Y., Gross, J., Beattie, M. S., Schmutzler, R., Wappenschmidt, B., Meindl, A., Ruehl, I., Fiebig, B., Sutter, C., Arnold, N., Deissler, H., Varon-Mateeva, R., Kast, K., Niederacher, D., Gadzicki, D., Caldes, T., De La Hoya, M., Nevanlinna, H., Aittomäki, K., Simard, J., Soucy, P., Spurdle, A. B., Holland, H., Chenevix-Trench, G., Easton, D. F. & Antoniou, A. C., Jan 19 2011, In: Journal of the National Cancer Institute. 103, 2, p. 105-116 12 p.

    Research output: Contribution to journalArticlepeer-review

    34 Scopus citations
  • Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers

    Neuhausen, S. L., Brummel, S., Ding, Y. C., Steele, L., Nathanson, K. L., Domchek, S., Rebbeck, T. R., Singer, C. F., Pfeiler, G., Lynch, H. T., Garber, J. E., Couch, F., Weitzel, J. N., Godwin, A., Narod, S. A., Ganz, P. A., Daly, M. B., Isaacs, C., Olopade, O. I., Tomlinson, G. E., & 4 othersRubinstein, W. S., Tung, N., Blum, J. L. & Gillen, D. L., Aug 2011, In: Cancer Epidemiology Biomarkers and Prevention. 20, 8, p. 1690-1702 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers

    The CONSIT TEAM study, Nov 1 2011, In: Human genetics. 130, 5, p. 685-699 15 p.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice

    Rowley, M., Ohashi, A., Mondal, G., Mills, L., Yang, L., Zhang, L., Sundsbak, R., Shapiro, V., Muders, M. H., Smyrk, T. & Couch, F. J., Apr 2011, In: Gastroenterology. 140, 4, p. 1303-1313.e3

    Research output: Contribution to journalArticlepeer-review

    56 Scopus citations
  • Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer

    Maxwell, C. A., Benítez, J., Gómez-Baldó, L., Osorio, A., Bonifaci, N., Fernández-Ramires, R., Costes, S. V., Guinó, E., Chen, H., Evans, G. J. R., Mohan, P., Català, I., Petit, A., Aguilar, H., Villanueva, A., Aytes, A., Serra-Musach, J., Rennert, G., Lejbkowicz, F., Peterlongo, P., & 127 othersManoukian, S., Peissel, B., Ripamonti, C. B., Bonanni, B., Viel, A., Allavena, A., Bernard, L., Radice, P., Friedman, E., Kaufman, B., Laitman, Y., Dubrovsky, M., Milgrom, R., Jakubowska, A., Cybulski, C., Gorski, B., Jaworska, K., Durda, K., Sukiennicki, G., Lubiński, J., Shugart, Y. Y., Domchek, S. M., Letrero, R., Weber, B. L., Hogervorst, F. B. L., Rookus, M. A., Collee, J. M., Devilee, P., Ligtenberg, M. J., van der Luijt, R. B., Aalfs, C. M., Waisfisz, Q., Wijnen, J., van Roozendaal, C. E. P., HEBON, EMBRACE, Easton, D. F., Peock, S., Cook, M., Oliver, C., Frost, D., Harrington, P., Lalloo, F., Eeles, R., Izatt, L., Chu, C., Eccles, D., Douglas, F., Brewer, C., Nevanlinna, H., Heikkinen, T., Couch, F. J., Wang, X., Lindor, N. M., Godwin, A. K., Caligo, M. A., Lombardi, G., Loman, N., Karlsson, P., Ehrencrona, H., von Wachenfeldt, A., SWE-BRCA, Barkardottir, R., Hamann, U., Rashid, M. U., Lasa, A., Caldés, T., Andrés, R., Schmitt, M., Assmann, V., Stevens, K., Offit, K., Curado, J., Tilgner, H., Guigó, R., Aiza, G., Brunet, J., Martrat, G., Urruticoechea, A., Blanco, I., Tihomirova, L., Goldgar, D. E., Buys, S., John, E. M., Miron, A., Southey, M., Daly, M. B., BCFR, Schmutzler, R. K., Wappenschmidt, B., Meindl, A., Arnold, N., Deissler, H., Varon-Mateeva, R., Sutter, C., Niederacher, D., Imyamitov, E., Sinilnikova, O. M., Sinilnikova, O. M., Stoppa-Lyonne, D., Mazoyer, S., Verny-Pierre, C., Castera, L., de Pauw, A., Bignon, Y. J., Uhrhammer, N., Peyrat, J. P., Vennin, P., Ferrer, S., Collonge-Rame, M. A., Mortemousque, I., GEMO Study Collaborators, S. C., Spurdle, A. B., Beesley, J., Chen, X., Healey, S., Barcellos-Hoff, M. H., Barcellos-Hoff, M. H., Gruber, S. B., Lázaro, C., Capellá, G., McGuffog, L., Nathanson, K. L., Chenevix-Trench, G., Fleisch, M. C., Moreno, V. & Pujana, M. A., Nov 1 2011, In: PLoS biology. 9, 11, e1001199.

    Research output: Contribution to journalArticlepeer-review

    63 Scopus citations
  • Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: Findings from the Breast Cancer Association Consortium

    kConFab51 & AOCS50,51, Aug 15 2011, In: Human molecular genetics. 20, 16, p. 3289-3303 15 p.

    Research output: Contribution to journalArticlepeer-review

    140 Scopus citations
  • Modification of BRCA1-associated breast and ovarian cancer risk by BRCA1-interacting genes

    Rebbeck, T. R., Mitra, N., Domchek, S. M., Wan, F., Friebel, T. M., Tran, T. V., Singer, C. F., Tea, M. K. M., Blum, J. L., Tung, N., Olopade, O. I., Weitzel, J. N., Lynch, H. T., Snyder, C. L., Garber, J. E., Antoniou, A. C., Peock, S., Evans, D. G., Paterson, J., Kennedy, M. J., & 18 othersDonaldson, A., Dorkins, H., Easton, D. F., Rubinstein, W. S., Daly, M. B., Isaacs, C., Nevanlinna, H., Couch, F. J., Andrulis, I. L., Freidman, E., Laitman, Y., Ganz, P. A., Tomlinson, G. E., Neuhausen, S. L., Narod, S. A., Phelan, C. M., Greenberg, R. & Nathanson, K. L., Sep 1 2011, In: Cancer research. 71, 17, p. 5792-5805 14 p.

    Research output: Contribution to journalArticlepeer-review

    39 Scopus citations
  • Mutant K-Ras increases GSK-3Β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer

    Zhang, J. S., Koenig, A., Harrison, A., Ugolkov, A. V., Fernandez-Zapico, M. E., Couch, F. J. & Billadeau, D. D., Aug 25 2011, In: Oncogene. 30, 34, p. 3705-3715 11 p.

    Research output: Contribution to journalArticlepeer-review

    41 Scopus citations
  • On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European populations

    Hamel, N., Feng, B. J., Foretova, L., Stoppa-Lyonnet, D., Narod, S. A., Imyanitov, E., Sinilnikova, O., Tihomirova, L., Lubinski, J., Gronwald, J., Gorski, B., Hansen, T. V. O., Nielsen, F. C., Thomassen, M., Yannoukakos, D., Konstantopoulou, I., Zajac, V., Ciernikova, S., Couch, F. J., Greenwood, C. M. T., & 2 othersGoldgar, D. E. & Foulkes, W. D., Mar 2011, In: European Journal of Human Genetics. 19, 3, p. 300-306 7 p.

    Research output: Contribution to journalArticlepeer-review

    64 Scopus citations
  • Prospective study of breast cancer incidence in women with a BRCA1 or BRCA2 mutation under surveillance with and without magnetic resonance imaging

    Warner, E., Hill, K., Causer, P., Plewes, D., Jong, R., Yaffe, M., Foulkes, W. D., Ghadirian, P., Lynch, H., Couch, F., Wong, J., Wright, F., Sun, P. & Narod, S. A., May 1 2011, In: Journal of Clinical Oncology. 29, 13, p. 1664-1669 6 p.

    Research output: Contribution to journalArticlepeer-review

    183 Scopus citations
  • Splicing and multifactorial analysis of intronic BRCA1 and BRCA2 sequence variants identifies clinically significant splicing aberrations up to 12 nucleotides from the intron/exon boundary

    Whiley, P. J., Guidugli, L., Walker, L. C., Healey, S., Thompson, B. A., Lakhani, S. R., Da Silva, L. M., Investigators, K., Tavtigian, S. V., Goldgar, D. E., Brown, M. A., Couch, F. J. & Spurdle, A. B., Jun 2011, In: Human mutation. 32, 6, p. 678-687 10 p.

    Research output: Contribution to journalArticlepeer-review

    41 Scopus citations
  • The role of KRAS rs61764370 in invasive epithelial ovarian cancer: Implications for clinical testing

    Pharoah, P. D. P., Palmieri, R. T., Ramus, S. J., Gayther, S. A., Andrulis, I. L., Anton-Culver, H., Antonenkova, N., Antoniou, A. C., Goldgar, D., Beattie, M. S., Beckmann, M. W., Birrer, M. J., Bogdanova, N., Bolton, K. L., Brewster, W., Brooks-Wilson, A., Brown, R., Butzow, R., Caldes, T., Caligo, M. A., & 93 othersCampbell, I., Chang-Claude, J., Chen, Y. A., Cook, L. S., Couch, F. J., Cramer, D. W., Cunningham, J. M., Despierre, E., Doherty, J. A., Dörk, T., Dürst, M., Eccles, D. M., Ekici, A. B., Easton, D., Fasching, P. A., De Fazio, A., Fenstermacher, D. A., Flanagan, J. M., Fridley, B. L., Friedman, E., Gao, B., Sinilnikova, O., Gentry-Maharaj, A., Godwin, A. K., Goode, E. L., Goodman, M. T., Gross, J., Hansen, T. V. O., Harnett, P., Rookus, M., Heikkinen, T., Hein, R., Høgdall, C., Høgdall, E., Iversen, E. S., Jakubowska, A., Johnatty, S. E., Karlan, B. Y., Kauff, N. D., Kaye, S. B., Chenevix-Trench, G., Kelemen, L. E., Kiemeney, L. A., Kjaer, S. K., Lambrechts, D., LaPolla, J. P., Lázaro, C., Le, N. D., Leminen, A., Leunen, K., Levine, D. A., Lu, Y., Lundvall, L., Macgregor, S., Marees, T., Massuger, L. F., McLaughlin, J. R., Menon, U., Montagna, M., Moysich, K. B., Narod, S. A., Nathanson, K. L., Nedergaard, L., Ness, R. B., Nevanlinna, H., Nickels, S., Osorio, A., Paul, J., Pearce, C. L., Phelan, C. M., Pike, M. C., Radice, P., Rossing, M. A., Schildkraut, J. M., Sellers, T. A., Singer, C. F., Song, H., Stram, D. O., Sutphen, R., Lindblom, A., Terry, K. L., Tsai, Y. Y., Van Altena, A. M., Vergote, I., Vierkant, R. A., Vitonis, A. F., Walsh, C., Wang-Gohrke, S., Wappenschmidt, B., Wu, A. H., Ziogas, A., Berchuck, A. & Risch, H. A., Jun 1 2011, In: Clinical Cancer Research. 17, 11, p. 3742-3750 9 p.

    Research output: Contribution to journalArticlepeer-review

    41 Scopus citations
  • Von Hippel-Lindau gene product directs cytokinesis: A new tumor suppressor function

    Sinha, S., Mondal, G., Hwang, E. J., Han, D. W., Dutta, S. K., Iyer, S., Karumanchi, S. A., Kim, K. I., Couch, F. J. & Mukhopadhyay, D., Jul 1 2011, In: Journal of cell science. 124, 13, p. 2132-2142 11 p.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • 2010

    A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

    Antoniou, A. C., Wang, X., Fredericksen, Z. S., McGuffog, L., Tarrell, R., Sinilnikova, O. M., Healey, S., Morrison, J., Kartsonaki, C., Lesnick, T., Ghoussaini, M., Barrowdale, D., Peock, S., Cook, M., Oliver, C., Frost, D., Eccles, D., Evans, D. G., Eeles, R., Izatt, L., & 158 othersChu, C., Douglas, F., Paterson, J., Stoppa-Lyonnet, D., Houdayer, C., Mazoyer, S., Giraud, S., Lasset, C., Remenieras, A., Caron, O., Hardouin, A., Berthet, P., Hogervorst, F. B. L., Rookus, M. A., Jager, A., Van Den Ouweland, A., Hoogerbrugge, N., Van Der Luijt, R. B., Meijers-Heijboer, H., G'mez García, E. B., Devilee, P., Vreeswijk, M. P. G., Lubinski, J., Jakubowska, A., Gronwald, J., Huzarski, T., Byrski, T., G'rski, B., Cybulski, C., Spurdle, A. B., Holland, H., Goldgar, D. E., John, E. M., Hopper, J. L., Southey, M., Buys, S. S., Daly, M. B., Terry, M. B., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Meindl, A., Preisler-Adams, S., Arnold, N., Niederacher, D., Sutter, C., Domchek, S. M., Nathanson, K. L., Rebbeck, T., Blum, J. L., Piedmonte, M., Rodriguez, G. C., Wakeley, K., Boggess, J. F., Basil, J., Blank, S. V., Friedman, E., Kaufman, B., Laitman, Y., Milgrom, R., Andrulis, I. L., Glendon, G., Ozcelik, H., Kirchhoff, T., Vijai, J., Gaudet, M. M., Altshuler, D., Guiducci, C., Loman, N., Harbst, K., Rantala, J., Ehrencrona, H., Gerdes, A. M., Thomassen, M., Sunde, L., Peterlongo, P., Manoukian, S., Bonanni, B., Viel, A., Radice, P., Caldes, T., De La Hoya, M., Singer, C. F., Fink-Retter, A., Greene, M. H., Mai, P. L., Loud, J. T., Guidugli, L., Lindor, N. M., Hansen, T. V. O., Nielsen, F. C., Blanco, I., Lazaro, C., Garber, J., Ramus, S. J., Gayther, S. A., Phelan, C., Narod, S., Szabo, C. I., Benitez, J., Osorio, A., Nevanlinna, H., Heikkinen, T., Caligo, M. A., Beattie, M. S., Hamann, U., Godwin, A. K., Montagna, M., Casella, C., Neuhausen, S. L., Karlan, B. Y., Tung, N., Toland, A. E., Weitzel, J., Olopade, O., Simard, J., Soucy, P., Rubinstein, W. S., Arason, A., Rennert, G., Martin, N. G., Montgomery, G. W., Chang-Claude, J., Flesch-Janys, D., Brauch, H., Severi, G., Baglietto, L., Cox, A., Cross, S. S., Miron, P., Gerty, S. M., Tapper, W., Yannoukakos, D., Fountzilas, G., Fasching, P. A., Beckmann, M. W., Dos Santos Silva, I., Peto, J., Lambrechts, D., Paridaens, R., Rüdiger, T., Försti, A., Winqvist, R., Pylkäs, K., Diasio, R. B., Lee, A. M., Eckel-Passow, J., Vachon, C., Blows, F., Driver, K., Dunning, A., Pharoah, P. P. D., Offit, K., Pankratz, V. S., Hakonarson, H., Chenevix-Trench, G., Easton, D. F. & Couch, F. J., Oct 2010, In: Nature Genetics. 42, 10, p. 885-892 8 p.

    Research output: Contribution to journalArticlepeer-review

    253 Scopus citations
  • Ancestry-shift refinement mapping of the C6orf97-ESR1 breast cancer susceptibility locus

    Stacey, S. N., Sulem, P., Zanon, C., Gudjonsson, S. A., Thorleifsson, G., Helgason, A., Jonasdottir, A., Besenbacher, S., Kostic, J. P., Fackenthal, J. D., Huo, D., Adebamowo, C., Ogundiran, T., Olson, J. E., Fredericksen, Z. S., Wang, X., Look, M. P., Sieuwerts, A. M., Martens, J. W. M., Pajares, I., & 41 othersGarcia-Prats, M. D., Ramon-Cajal, J. M., de Juan, A., Panadero, A., Ortega, E., Aben, K. K. H., Vermeulen, S. H., Asadzadeh, F., Anton van Engelenburg, K. C., Margolin, S., Shen, C. Y., Wu, P. E., Försti, A., Lenner, P., Henriksson, R., Johansson, R., Enquist, K., Hallmans, G., Jonsson, T., Sigurdsson, H., Alexiusdottir, K., Gudmundsson, J., Sigurdsson, A., Frigge, M. L., Gudmundsson, L., Kristjansson, K., Halldorsson, B. V., Styrkarsdottir, U., Gulcher, J. R., Hemminki, K., Lindblom, A., Kiemeney, L. A., Mayordomo, J. I., Foekens, J. A., Couch, F. J., Olopade, O. I., Gudbjartsson, D. F., Thorsteinsdottir, U., Rafnar, T., Johannsson, O. T. & Stefansson, K., Jul 2010, In: PLoS genetics. 6, 7, p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

    71 Scopus citations
  • Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: A combined case-control study

    Milne, R. L., Gaudet, M. M., Spurdle, A. B., Fasching, P. A., Couch, F. J., Benítez, J., Arias Pérez, J. I., Zamora, M. P., Malats, N., dos Santos Silva, I., Gibson, L. J., Fletcher, O., Johnson, N., Anton-Culver, H., Ziogas, A., Figueroa, J., Brinton, L., Sherman, M. E., Lissowska, J., Hopper, J. L., & 64 othersDite, G. S., Apicella, C., Southey, M. C., Sigurdson, A. J., Linet, M. S., Schonfeld, S. J., Freedman, D. M., Mannermaa, A., Kosma, V. M., Kataja, V., Auvinen, P., Andrulis, I. L., Glendon, G., Knight, J. A., Weerasooriya, N., Cox, A., Reed, M. W. R., Cross, S. S., Dunning, A. M., Ahmed, S., Shah, M., Brauch, H., Ko, Y. D., Brüning, T., Brauch, H., Lambrechts, D., Reumers, J., Smeets, A., Wang-Gohrke, S., Hall, P., Czene, K., Liu, J., Irwanto, A. K., Chenevix-Trench, G., Holland, H., Fab, K. C., Giles, G. G., Baglietto, L., Severi, G., Bojensen, S. E., Nordestgaard, B. G., Flyger, H., John, E. M., West, D. W., Whittemore, A. S., Vachon, C., Olson, J. E., Fredericksen, Z., Kosel, M., Hein, R., Vrieling, A., Flesch-Janys, D., Heinz, J., Beckmann, M. W., Heusinger, K., Ekici, A. B., Haeberle, L., Humphreys, M. K., Morrison, J., Easton, D. F., Pharoah, P. D., García-Closas, M., Goode, E. L. & Chang-Claude, J., Dec 31 2010, In: Breast Cancer Research. 12, 6, R110.

    Research output: Contribution to journalArticlepeer-review

    73 Scopus citations
  • Association between a germline OCA2 polymorphism at chromosome 15q13.1 and estrogen receptor-negative breast cancer survival

    Azzato, E. M., Tyrer, J., Fasching, P. A., Beckmann, M. W., Ekici, A. B., Schulz-Wendtland, R., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Milne, R. L., Arias, J. I., Menéndez, P., Benítez, J., Chang-Claude, J., Hein, R., Wang-Gohrke, S., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., & 35 othersMargolin, S., Mannermaa, A., Kosma, V. M., Kataja, V., Beesley, J., Chen, X., Chenevix-Trench, G., Couch, F. J., Olson, J. E., Fredericksen, Z. S., Wang, X., Giles, G. G., Severi, G., Baglietto, L., Southey, M. C., Devilee, P., Tollenaar, R. A. E. M., Seynaeve, C., García-Closas, M., Lissowska, J., Sherman, M. E., Bolton, K. L., Hall, P., Czene, K., Cox, A., Brock, I. W., Elliott, G. C., Reed, M. W. R., Greenberg, D., Anton-Culver, H., Ziogas, A., Humphreys, M., Easton, D. F., Caporaso, N. E. & Pharoah, P. D. P., May 2010, In: Journal of the National Cancer Institute. 102, 9, p. 650-662 13 p.

    Research output: Contribution to journalArticlepeer-review

    44 Scopus citations
  • Association of genetic variation in mitotic kinases with breast cancer risk

    Wang, X., Fredericksen, Z. S., Vierkant, R. A., Kosel, M. L., Pankratz, V. S., Cerhan, J. R., Justenhoven, C., Brauch, H., Olson, J. E. & Couch, F. J., Jan 2010, In: Breast Cancer Research and Treatment. 119, 2, p. 453-462 10 p.

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations
  • Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome

    Couch, F. J., Wang, X., Bamlet, W. R., De Andrade, M., Petersen, G. M. & McWilliams, R. R., Jan 2010, In: Cancer Epidemiology Biomarkers and Prevention. 19, 1, p. 251-257 7 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality

    Domchek, S. M., Friebel, T. M., Singer, C. F., Gareth Evans, D., Lynch, H. T., Isaacs, C., Garber, J. E., Neuhausen, S. L., Matloff, E., Eeles, R., Pichert, G., Van T'veer, L., Tung, N., Weitzel, J. N., Couch, F. J., Rubinstein, W. S., Ganz, P. A., Daly, M. B., Olopade, O. I., Tomlinson, G., & 3 othersSchildkraut, J., Blum, J. L. & Rebbeck, T. R., Sep 1 2010, In: JAMA. 304, 9, p. 967-975 9 p.

    Research output: Contribution to journalArticlepeer-review

    933 Scopus citations
  • Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

    Engel, C., Versmold, B., Wappenschmidt, B., Simard, J., Easton, D. F., Peock, S., Cook, M., Oliver, C., Frost, D., Mayes, R., Evans, D. G., Eeles, R., Paterson, J., Brewer, C., McGuffog, L., Antoniou, A. C., Stoppa-Lyonnet, D., Sinilnikova, O. M., Barjhoux, L., Frenay, M., & 48 othersMichel, C., Leroux, D., Dreyfus, H., Toulas, C., Gladieff, L., Uhrhammer, N., Bignon, Y. J., Meindl, A., Arnold, N., Varon-Mateeva, R., Niederacher, D., Preisler-Adams, S., Kast, K., Deissler, H., Sutter, C., Gadzicki, D., Chenevix-Trench, G., Spurdle, A. B., Chen, X., Beesley, J., Olsson, H., Kristoffersson, U., Ehrencrona, H., Liljegren, A., Van Der Luijt, R. B., Van Os, T. A., Van Leeuwen, F. E., Domchek, S. M., Rebbeck, T. R., Nathanson, K. L., Osorio, A., Ramón Y Cajal, T., Konstantopoulou, I., Benítez, J., Friedman, E., Kaufman, B., Laitman, Y., Mai, P. L., Greene, M. H., Nevanlinna, H., Aittomäki, K., Szabo, C. I., Caldes, T., Couch, F. J., Andrulis, I. L., Godwin, A. K., Hamann, U. & Schmutzler, R. K., Nov 2010, In: Cancer Epidemiology Biomarkers and Prevention. 19, 11, p. 2859-2868 10 p.

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations
  • Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: Implications for risk prediction

    Antoniou, A. C., Beesley, J., McGuffog, L., Sinilnikova, O. M., Healey, S., Neuhausen, S. L., Ding, Y. C., Rebbeck, T. R., Weitzel, J. N., Lynch, H. T., Isaacs, C., Ganz, P. A., Tomlinson, G., Olopade, O. I., Couch, F. J., Wang, X., Lindor, N. M., Pankratz, V. S., Radice, P., Manoukian, S., & 158 othersPeissel, B., Zaffaroni, D., Barile, M., Viel, A., Allavena, A., Dall'Olio, V., Peterlongo, P., Szabo, C. I., Zikan, M., Claes, K., Poppe, B., Foretova, L., Mai, P. L., Greene, M. H., Rennert, G., Lejbkowicz, F., Glendon, G., Ozcelik, H., Andrulis, I. L., Thomassen, M., Gerdes, A. M., Sunde, L., Cruger, D., Jensen, U. B., Caligo, M., Friedman, E., Kaufman, B., Laitman, Y., Milgrom, R., Dubrovsky, M., Cohen, S., Borg, A., Jernström, H., Lindblom, A., Rantala, J., Stenmark-Askmalm, M., Melin, B., Nathanson, K., Domchek, S., Jakubowska, A., Lubinski, J., Huzarski, T., Osorio, A., Lasa, A., Durán, M., Tejada, M. I., Godino, J., Benitez, J., Hamann, U., Kriege, M., Hoogerbrugge, N., Van Der Luijt, R. B., Van Asperen, C. J., Devilee, P., Meijers-Heijboer, E. J., Blok, M. J., Aalfs, C. M., Hogervorst, F., Rookus, M., Cook, M., Oliver, C., Frost, D., Conroy, D., Evans, D. G., Lalloo, F., Pichert, G., Davidson, R., Cole, T., Cook, J., Paterson, J., Hodgson, S., Morrison, P. J., Porteous, M. E., Walker, L., Kennedy, M. J., Dorkins, H., Peock, S., Godwin, A. K., Stoppa-Lyonnet, D., De Pauw, A., Mazoyer, S., Bonadona, V., Lasset, C., Dreyfus, H., Leroux, D., Hardouin, A., Berthet, P., Faivre, L., Loustalot, C., Noguchi, T., Sobol, H., Rouleau, E., Nogues, C., Frénay, M., Vénat-Bouvet, L., Hopper, J. L., Daly, M. B., Terry, M. B., John, E. M., Buys, S. S., Yassin, Y., Miron, A., Goldgar, D., Singer, C. F., Dressler, A. C., Gschwantler-Kaulich, D., Pfeiler, G., Hansen, T. V. O., Jnson, L., Agnarsson, B. A., Kirchhoff, T., Offit, K., Devlin, V., Dutra-Clarke, A., Piedmonte, M., Rodriguez, G. C., Wakeley, K., Boggess, J. F., Basil, J., Schwartz, P. E., Blank, S. V., Toland, A. E., Montagna, M., Casella, C., Imyanitov, E., Tihomirova, L., Blanco, I., Lazaro, C., Ramus, S. J., Sucheston, L., Karlan, B. Y., Gross, J., Schmutzler, R., Wappenschmidt, B., Engel, C., Meindl, A., Lochmann, M., Arnold, N., Heidemann, S., Varon-Mateeva, R., Niederacher, D., Sutter, C., Deissler, H., Gadzicki, D., Preisler-Adams, S., Kast, K., Schönbuchner, I., Caldes, T., De La Hoya, M., Aittomäki, K., Nevanlinna, H., Simard, J., Spurdle, A. B., Holland, H., Chen, X., Platte, R., Chenevix-Trench, G. & Easton, D. F., Dec 1 2010, In: Cancer research. 70, 23, p. 9742-9754 13 p.

    Research output: Contribution to journalArticlepeer-review

    144 Scopus citations
  • Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

    Gaudet, M. M., Kirchhoff, T., Green, T., Vijai, J., Korn, J. M., Guiducci, C., Segrè, A. V., McGee, K., McGuffog, L., Kartsonaki, C., Morrison, J., Healey, S., Sinilnikova, O. M., Stoppa-Lyonnet, D., Mazoyer, S., Gauthier-Villars, M., Sobol, H., Longy, M., Frenay, M., Hogervorst, F. B. L., & 96 othersRookus, M. A., Collée, J. M., Hoogerbrugge, N., van Roozendaal, K. E. P., Piedmonte, M., Rubinstein, W., Nerenstone, S., Van Le, L., Blank, S. V., Caldés, T., De la Hoya, M., Nevanlinna, H., Aittomäki, K., Lazaro, C., Blanco, I., Arason, A., Johannsson, O. T., Barkardottir, R. B., Devilee, P., Olopade, O. I., Neuhausen, S. L., Wang, X., Fredericksen, Z. S., Peterlongo, P., Manoukian, S., Barile, M., Viel, A., Radice, P., Phelan, C. M., Narod, S., Rennert, G., Lejbkowicz, F., Flugelman, A., Andrulis, I. L., Glendon, G., Ozcelik, H., Toland, A. E., Montagna, M., D'Andrea, E., Friedman, E., Laitman, Y., Borg, A., Beattie, M., Ramus, S. J., Domchek, S. M., Nathanson, K. L., Rebbeck, T., Spurdle, A. B., Chen, X., Holland, H., John, E. M., Hopper, J. L., Buys, S. S., Daly, M. B., Southey, M. C., Terry, M. B., Tung, N., Hansen, T. V. O., Nielsen, F. C., Greene, M. I., Mai, P. L., Osorio, A., Durán, M., Andres, R., Benítez, J., Weitzel, J. N., Garber, J., Hamann, U., Peock, S., Cook, M., Oliver, C., Frost, D., Platte, R., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Walker, L., Eason, J., Barwell, J., Godwin, A. K., Schmutzler, R. K., Wappenschmidt, B., Engert, S., Arnold, N., Gadzicki, D., Dean, M., Gold, B., Klein, R. J., Couch, F. J., Chenevix-Trench, G., Easton, D. F., Daly, M. J., Antoniou, A. C., Altshuler, D. M. & Offit, K., Oct 2010, In: PLoS genetics. 6, 10, p. 1-12 12 p., e1001183.

    Research output: Contribution to journalArticlepeer-review

    75 Scopus citations
  • Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

    Wang, X., Pankratz, V. S., Fredericksen, Z., Tarrell, R., Karaus, M., McGuffog, L., Pharaoh, P. D. P., Ponder, B. A. J., Dunning, A. M., Peock, S., Cook, M., Oliver, C., Frost, D., Sinilnikova, O. M., Stoppa-Lyonnet, D., Mazoyer, S., Houdayer, C., Hogervorst, F. B. L., Hooning, M. J., Ligtenberg, M. J., & 24 othersSpurdle, A., Chenevix-Trench, G., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Meindl, A., Domchek, S. M., Nathanson, K. L., Rebbeck, T. R., Singer, C. F., Gschwantler-Kaulich, D., Dressler, C., Fink, A., Szabo, C. I., Zikan, M., Foretova, L., Claes, K., Thomas, G., Hoover, R. N., Hunter, D. J., Chanock, S. J., Easton, D. F., Antoniou, A. C. & Couch, F. J., Apr 23 2010, In: Human molecular genetics. 19, 14, p. 2886-2897 12 p., ddq174.

    Research output: Contribution to journalArticlepeer-review

    52 Scopus citations
  • Detection of splicing aberrations caused by BRCA1 and BRCA2 sequence variants encoding missense substitutions: Implications for prediction of pathogenicity

    Walker, L. C., Whiley, P. J., Couch, F. J., Farrugia, D. J., Healey, S., Eccles, D. M., Lin, F., Butler, S. A., Goff, S. A., Thompson, B. A., Lakhani, S. R., Da Silva, L. M., Tavtigian, S. V., Goldgar, D. E., Brown, M. A. & Spurdle, A. B., Jun 2010, In: Human mutation. 31, 6, p. E1484-E1505

    Research output: Contribution to journalArticlepeer-review

    49 Scopus citations
  • Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers

    Walker, L. C., Fredericksen, Z. S., Wang, X., Tarrell, R., Pankratz, V. S., Lindor, N. M., Beesley, J., Healey, S., Chen, X., Stoppa-Lyonnet, D., Tirapo, C., Giraud, S., Mazoyer, S., Muller, D., Fricker, J. P., Delnatte, C. D., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Schönbuchner, I., & 53 othersDeissler, H., Meindl, A., Hogervorst, F. B., Verheus, M., Hooning, M. J., van den Ouweland, A. M. W., Nelen, M. R., Ausems, M. G. E. M., Aalfs, C. M., van Asperen, C. J., Devilee, P., Gerrits, M. M., Waisfisz, Q., Szabo, C. I., Easton, D. F., Peock, S., Cook, M., Oliver, C. T., Frost, D., Harrington, P., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Chu, C., Davidson, R., Eccles, D., Ong, K. R., Cook, J., Rebbeck, T., Nathanson, K. L., Domchek, S. M., Singer, C. F., Gschwantler-Kaulich, D., Dressler, A. C., Pfeiler, G., Godwin, A. K., Heikkinen, T., Nevanlinna, H., Agnarsson, B. A., Caligo, M. A., Olsson, H., Kristoffersson, U., Liljegren, A., Arver, B., Karlsson, P., Melin, B., Sinilnikova, O. M., McGuffog, L., Antoniou, A. C., Chenevix-Trench, G., Spurdle, A. B. & Couch, F. J., Nov 29 2010, In: Breast Cancer Research. 12, 6, R102.

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations
  • Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer

    Li, J., Eriksson, L., Humphreys, K., Czene, K., Liu, J., Tamimi, R. M., Lindström, S., Hunter, D. J., Vachon, C. M., Couch, F. J., Scott, C. G., Lagiou, P. & Hall, P., Mar 9 2010, In: Breast Cancer Research. 12, 2, R19.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • Linkage analysis of obesity phenotypes in pre- and post-menopausal women from a United States mid-western population

    Kelemen, L. E., Atkinson, E. J., de Andrade, M., Pankratz, V. S., Cunningham, J. M., Wang, A., Hilker, C. A., Couch, F. J., Sellers, T. A. & Vachon, C. M., Nov 9 2010, In: BMC Medical Genetics. 11, 1, 156.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls

    Fletcher, O., Johnson, N., Dos Santos Silva, I., Ashworth, A., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Burwinkel, B., Bartram, C. R., Meindl, A., Schmutzler, R. K., Cox, A., Brock, I., Elliott, G., Reed, M. W. R., Southey, M. C., Smith, L., Spurdle, A. B., Hopper, J. L., & 68 othersCouch, F. J., Olson, J. E., Wang, X., Fredericksen, Z., Schürmann, P., Waltes, R., Bremer, M., Dörk, T., Devilee, P., Van Asperen, C. J., Tollenaar, R. A. E. M., Seynaeve, C., Hall, P., Czene, K., Humphreys, K., Liu, J., Ahmed, S., Dunning, A. M., Maranian, M., Pharoah, P. D. P., Chenevix-Trench, G., Beesley, J., Bogdanova, N. V., Antonenkova, N. N., Zalutsky, I. V., Anton-Culver, H., Ziogas, A., Brauch, H., Ko, Y. D., Hamann, U., Fasching, P. A., Strick, R., Ekici, A. B., Beckmann, M. W., Giles, G. G., Severi, G., Baglietto, L., English, D. R., Milne, R. L., Benítez, J., Arias, J. I., Pita, G., Nordestgaard, B. G., Bojesen, S. E., Flyger, H., Kang, D., Yoo, K. Y., Noh, D. Y., Mannermaa, A., Kataja, V., Kosma, V. M., García-Closas, M., Chanock, S., Lissowska, J., Brinton, L. A., Chang-Claude, J., Wang-Gohrke, S., Broeks, A., Schmidt, M. K., Van Leeuwen, F. E., Van't Veer, L. J., Margolin, S., Lindblom, A., Humphreys, M. K., Morrison, J., Platte, R., Easton, D. F. & Peto, J., Sep 2010, In: Cancer Epidemiology Biomarkers and Prevention. 19, 9, p. 2143-2151 9 p.

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations
  • Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers

    Domchek, S. M., Friebel, T. M., Garber, J. E., Isaacs, C., Matloff, E., Eeles, R., Evans, D. G., Rubinstein, W., Singer, C. F., Rubin, S., Lynch, H. T., Daly, M. B., Weitzel, J., Ganz, P. A., Pichert, G., Olopade, O. I., Tomlinson, G., Tung, N., Blum, J. L., Couch, F., & 1 othersRebbeck, T. R., Nov 2010, In: Breast Cancer Research and Treatment. 124, 1, p. 195-203 9 p.

    Research output: Contribution to journalArticlepeer-review

    52 Scopus citations
  • Predicting BRCA1 and BRCA2 gene mutation carriers: Comparison of PENN II model to previous study

    Lindor, N. M., Johnson, K. J., Harvey, H., Shane Pankratz, V., Domchek, S. M., Hunt, K., Wilson, M., Cathie Smith, M. & Couch, F., Dec 2010, In: Familial Cancer. 9, 4, p. 495-502 8 p.

    Research output: Contribution to journalArticlepeer-review

    31 Scopus citations
  • Risk of ovarian cancer and inherited variants in relapse-associated genes

    Peedicayil, A., Vierkant, R. A., Hartmann, L. C., Fridley, B. L., Fredericksen, Z. S., White, K. L., Elliott, E. A., Phelan, C. M., Tsai, Y. Y., Berchuck, A., Iversen, E. S., Couch, F. J., Peethamabaran, P., Larson, M. C., Kalli, K. R., Kosel, M. L., Shridhar, V., Rider, D. N., Liebow, M., Cunningham, J. M., & 3 othersSchildkraut, J. M., Sellers, T. A. & Goode, E. L., Jan 27 2010, In: PloS one. 5, 1, e8884.

    Research output: Contribution to journalArticlepeer-review

    20 Scopus citations
  • Subtypes of familial breast tumours revealed by expression and copy number profiling

    Waddell, N., Arnold, J., Cocciardi, S., Da Silva, L., Marsh, A., Riley, J., Johnstone, C. N., Orloff, M., Assie, G., Eng, C., Reid, L., Keith, P., Yan, M., Fox, S., Devilee, P., Godwin, A. K., Hogervorst, F. B. L., Couch, F., Investigators, K., Grimmond, S., & 5 othersFlanagan, J. M., Khanna, K., Simpson, P. T., Lakhani, S. R. & Chenevix-Trench, G., Oct 2010, In: Breast Cancer Research and Treatment. 123, 3, p. 661-677 17 p.

    Research output: Contribution to journalArticlepeer-review

    72 Scopus citations
  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: A collaborative analysis of data for 10,159 cases from 12 studies

    Blows, F. M., Driver, K. E., Schmidt, M. K., Broeks, A., van Leeuwen, F. E., Wesseling, J., Cheang, M. C., Gelmon, K., Nielsen, T. O., Blomqvist, C., Heikkila, P., Heikkinen, T., Nevanlinna, H., Akslen, L. A., Bégin, L. R., Foulkes, W. D., Couch, F. J., Wang, X., Cafourek, V., Olson, J. E., & 23 othersBaglietto, L., Giles, G. G., Severi, G., McLean, C. A., Southey, M. C., Rakha, E., Green, A. R., Ellis, I. O., Sherman, M. E., Lissowska, J., Anderson, W. F., Cox, A., Cross, S. S., Reed, M. W. R., Provenzano, E., Dawson, S. J., Dunning, A. M., Humphreys, M., Easton, D. F., García-Closas, M., Caldas, C., Pharoah, P. D. & Huntsman, D., May 2010, In: PLoS Medicine. 7, 5

    Research output: Contribution to journalArticlepeer-review

    594 Scopus citations
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