Fergus J Couch

Fergus J Couch, PhD

Chair, Division of Experimental Pathology

1991 …2023

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  • Article

    Mutation screening of RAD51C in high-risk breast and ovarian cancer families

    Lu, W., Wang, X., Lin, H., Lindor, N. M. & Couch, F. J., Sep 2012, In: Familial Cancer. 11, 3, p. 381-385 5 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • Mutations in BRCA1/2 and Other Panel Genes in Patients With Metastatic Breast Cancer -Association With Patient and Disease Characteristics and Effect on Prognosis

    Fasching, P. A., Yadav, S., Hu, C., Wunderle, M., Häberle, L., Hart, S. N., Rübner, M., Polley, E. C., Lee, K. Y., Gnanaolivu, R. D., Hadji, P., Hübner, H., Tesch, H., Ettl, J., Overkamp, F., Lux, M. P., Ekici, A. B., Volz, B., Uhrig, S., Lüftner, D., & 17 othersWallwiener, M., Müller, V., Belleville, E., Untch, M., Kolberg, H. C., Beckmann, M. W., Reis, A., Hartmann, A., Janni, W., Wimberger, P., Taran, F. A., Fehm, T. N., Wallwiener, D., Brucker, S. Y., Schneeweiss, A., Hartkopf, A. D. & Couch, F. J., May 20 2021, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 39, 15, p. 1619-1630 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer

    Castilla, L. H., Couch, F. J., Erdos, M. R., Hoskins, K. F., Calzone, K., Garber, J. E., Boyd, J., Lubin, M. B., Deshano, M. L., Brody, L. C., Collins, F. S. & Weber, B. L., Dec 1994, In: Nature Genetics. 8, 4, p. 387-391 5 p.

    Research output: Contribution to journalArticlepeer-review

    350 Scopus citations
  • Mutations in the ryanodine receptor gene in central core disease and malignant hyperthermia

    Quane, K. A., Healy, J. M. S., Keating, K. E., Manning, B. M., Couch, F. J., Palmucci, L. M., Doriguzzi, C., Fagerlund, T. H., Berg, K., Ording, H., Bendixen, D., Mortier, W., Linz, U., Muller, C. R. & McCarthy, T. V., Sep 1993, In: Nature Genetics. 5, 1, p. 51-55 5 p.

    Research output: Contribution to journalArticlepeer-review

    287 Scopus citations
  • Mutations of the BRCA2 gene in ovarian carcinomas

    Takahashi, H., Chiu, H. C., Bandera, C. A., Behbakht, K., Liu, P. C., Couch, F. J., Weber, B. L., LiVolsi, V. A., Furusato, M., Rebane, B. A., Cardonick, A., Benjamin, I., Morgan, M. A., King, S. A., Mikuta, J. J., Rubin, S. C. & Boyd, J., Jun 15 1996, In: Cancer research. 56, 12, p. 2738-2741 4 p.

    Research output: Contribution to journalArticlepeer-review

    105 Scopus citations
  • Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2

    Ahmed, S., Thomas, G., Ghoussaini, M., Healey, C. S., Humphreys, M. K., Platte, R., Morrison, J., Maranian, M., Pooley, K. A., Luben, R., Eccles, D., Evans, D. G., Fletcher, O., Johnson, N., Dos Santos Silva, I., Peto, J., Stratton, M. R., Rahman, N., Jacobs, K., Prentice, R., & 115 othersAnderson, G. L., Rajkovic, A., Curb, J. D., Ziegler, R. G., Berg, C. D., Buys, S. S., McCarty, C. A., Feigelson, H. S., Calle, E. E., Thun, M. J., Diver, W. R., Bojesen, S., Nordestgaard, B. G., Flyger, H., Dörk, T., Schürmann, P., Hillemanns, P., Karstens, J. H., Bogdanova, N. V., Antonenkova, N. N., Zalutsky, I. V., Bermisheva, M., Fedorova, S., Khusnutdinova, E., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Devilee, P., Van Asperen, C. J., Tollenaar, R. A. E. M., Seynaeve, C., Garcia-Closas, M., Lissowska, J., Brinton, L., Peplonska, B., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Hopper, J. L., Southey, M. C., Smith, L., Spurdle, A. B., Schmidt, M. K., Broeks, A., Van Hien, R. R., Cornelissen, S., Milne, R. L., Ribas, G., González-Neira, A., Benitez, J., Schmutzler, R. K., Burwinkel, B., Bartram, C. R., Meindl, A., Brauch, H., Justenhoven, C., Hamann, U., Chang-Claude, J., Hein, R., Wang-Gohrke, S., Lindblom, A., Margolin, S., Mannermaa, A., Kosma, V. M., Kataja, V., Olson, J. E., Wang, X., Fredericksen, Z., Giles, G. G., Severi, G., Baglietto, L., English, D. R., Hankinson, S. E., Cox, D. G., Kraft, P., Vatten, L. J., Hveem, K., Kumle, M., Sigurdson, A., Doody, M., Bhatti, P., Alexander, B. H., Hooning, M. J., Van Den Ouweland, A. M. W., Oldenburg, R. A., Schutte, M., Hall, P., Czene, K., Liu, J., Li, Y., Cox, A., Elliott, G., Brock, I., Reed, M. W. R., Shen, C. Y., Yu, J. C., Hsu, G. C., Chen, S. T., Anton-Culver, H., Ziogas, A., Andrulis, I. L., Knight, J. A., Beesley, J., Goode, E. L., Couch, F., Chenevix-Trench, G., Hoover, R. N., Ponder, B. A. J., Hunter, D. J., Pharoah, P. D. P., Dunning, A. M., Chanock, S. J. & Easton, D. F., May 2009, In: Nature Genetics. 41, 5, p. 585-590 6 p.

    Research output: Contribution to journalArticlepeer-review

    387 Scopus citations
  • No association between a candidate TCF7L2 variant and risk of breast or ovarian cancer

    Goode, E. L., Szabo, C., Prokunina-Olsson, L., Vierkant, R. A., Fredericksen, Z. S., Collins, F. S., White, K. L., Schmidt, M., Fridley, B. L. & Couch, F. J., Sep 4 2009, In: BMC cancer. 9, p. 312 1 p., 312.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: A multi-center cohort study

    Rebbeck, T. R., Antoniou, A. C., Llopis, T. C., Nevanlinna, H., Aittomäki, K., Simard, J., Spurdle, A. B., Couch, F. J., Pereira, L. H. M., Greene, M. H., Andrulis, I. L., Pasche, B., Kaklamani, V., Hamann, U., Szabo, C., Peock, S., Cook, M., Harrington, P. A., Donaldson, A., Male, A. M., & 24 othersGardiner, C. A., Gregory, H., Side, L. E., Robinson, A. C., Emmerson, L., Ellis, I., Peyrat, J. P., Fournier, J., Vennin, P., Adenis, C., Muller, D., Fricker, J. P., Longy, M., Sinilnikova, O. M., Stoppa-Lyonnet, D., Schmutzler, R. K., Versmold, B., Engel, C., Meindl, A., Kast, K., Schaefer, D., Froster, U. G., Chenevix-Trench, G. & Easton, D. F., May 1 2009, In: Breast Cancer Research and Treatment. 115, 1, p. 185-192 8 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • No evidence for association of inherited variation in genes involved in mitosis and percent mammographic density

    Vachon, C. M., Li, J., Scott, C. G., Hall, P., Czene, K., Wang, X., Liu, J., Fredericksen, Z. S., Rider, D. N., Wu, F. F., Olson, J. E., Cunningham, J. M., Stevens, K. N., Sellers, T. A., Pankratz, S. V. & Couch, F. J., Jan 7 2012, In: Breast Cancer Research. 14, 1, R7.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • No evidence that GATA3 rs570613 SNP modifies breast cancer risk

    Johnatty, S. E., Couch, F. J., Fredericksen, Z., Tarrell, R., Spurdle, A. B., Beesley, J., Chen, X., Gschwantler-Kaulich, D., Singer, C. F., Fuerhauser, C., Fink-Retter, A., Domchek, S. M., Nathanson, K. L., Pankratz, V. S., Lindor, N. M., Godwin, A. K., Caligo, M. A., Hopper, J., Southey, M. C., Giles, G. G., & 45 othersJustenhoven, C., Brauch, H., Hamann, U., Ko, Y. D., Heikkinen, T., Aaltonen, K., Aittomäki, K., Blomqvist, C., Nevanlinna, H., Hall, P., Czene, K., Liu, J., Peock, S., Cook, M., Platte, R., Gareth Evans, D., Lalloo, F., Eeles, R., Pichert, G., Eccles, D., Davidson, R., Cole, T., Cook, J., Douglas, F., Chu, C., Hodgson, S., Paterson, J., Hogervorst, F. B. L., Rookus, M. A., Seynaeve, C., Wijnen, J., Vreeswijk, M., Ligtenberg, M., Van Der Luijt, R. B., Van Os, T. A. M., Gille, H. J. P., Blok, M. J., Issacs, C., Humphreys, M. K., McGuffog, L., Healey, S., Sinilnikova, O., Antoniou, A. C., Easton, D. F. & Chenevix-Trench, G., Sep 2009, In: Breast Cancer Research and Treatment. 117, 2, p. 371-379 9 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: Implications for gene panel testing

    Australian Ovarian Cancer Study Group, KConFab investigators, Lifepool Investigators & NBCS Investigators, Feb 26 2016, In: Journal of medical genetics. 53, 5, p. 298-309 12 p.

    Research output: Contribution to journalArticlepeer-review

    68 Scopus citations
  • Non-BRCA familial breast cancer: review of reported pathology and molecular findings

    Keeney, M. G., Couch, F. J., Visscher, D. W. & Lindor, N. M., Jun 2017, In: Pathology. 49, 4, p. 363-370 8 p.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Novel associations between common breast cancer susceptibility variants and risk-predicting mammographic density measures

    Stone, J., Thompson, D. J., Dos Santos Silva, I., Scott, C., Tamimi, R. M., Lindstrom, S., Kraft, P., Hazra, A., Li, J., Eriksson, L., Czene, K., Hall, P., Jensen, M., Cunningham, J., Olson, J. E., Purrington, K., Couch, F. J., Brown, J., Leyland, J., Warren, R. M. L., & 40 othersLuben, R. N., Khaw, K. T., Smith, P., Wareham, N. J., Jud, S. M., Heusinger, K., Beckmann, M. W., Douglas, J. A., Shah, K. P., Chan, H. P., Helvie, M. A., Marchand, L. L., Kolonel, L. N., Woolcott, C., Maskarinec, G., Haiman, C., Giles, G. G., Baglietto, L., Krishnan, K., Southey, M. C., Apicella, C., Andrulis, I. L., Knight, J. A., Ursin, G., Alnaes, G. I. G., Kristensen, V. N., Borresen-Dale, A. L., Gram, I. T., Bolla, M. K., Wang, Q., Michailidou, K., Dennis, J., Simard, J., Pharoah, P., Dunning, A. M., Easton, D. F., Fasching, P. A., Pankratz, V. S., Hopper, J. L. & Vachon, C. M., Jun 15 2015, In: Cancer research. 75, 12, p. 2457-2467 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    42 Scopus citations
  • Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin

    Hall, J. C., Marlow, L. A., Mathias, A. C., Dawson, L. K., Durham, W. F., Meshaw, K. A., Mullin, R. J., Synnott, A. J., Small, D. L., Krishna, M., Hoff, D., Schüler, J., Hart, S. N., Couch, F. J., Colon-Otero, G. & Copland, J. A., May 10 2016, In: Journal of Translational Medicine. 14, 1, 129.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • N-terminal pro brain natriuretic peptide, sst2, and galectin-3 levels in breast cancer survivors

    Patel, S. R., Herrmann, J., Vierkant, R. A., Olson, J. E., Couch, F. J., Hazim, A., Sloan, J. A., Loprinzi, C. L. & Ruddy, K. J., Aug 1 2021, In: Journal of Clinical Medicine. 10, 15, 3313.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers

    Domchek, S. M., Friebel, T. M., Garber, J. E., Isaacs, C., Matloff, E., Eeles, R., Evans, D. G., Rubinstein, W., Singer, C. F., Rubin, S., Lynch, H. T., Daly, M. B., Weitzel, J., Ganz, P. A., Pichert, G., Olopade, O. I., Tomlinson, G., Tung, N., Blum, J. L., Couch, F., & 1 othersRebbeck, T. R., Nov 2010, In: Breast Cancer Research and Treatment. 124, 1, p. 195-203 9 p.

    Research output: Contribution to journalArticlepeer-review

    52 Scopus citations
  • On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European populations

    Hamel, N., Feng, B. J., Foretova, L., Stoppa-Lyonnet, D., Narod, S. A., Imyanitov, E., Sinilnikova, O., Tihomirova, L., Lubinski, J., Gronwald, J., Gorski, B., Hansen, T. V. O., Nielsen, F. C., Thomassen, M., Yannoukakos, D., Konstantopoulou, I., Zajac, V., Ciernikova, S., Couch, F. J., Greenwood, C. M. T., & 2 othersGoldgar, D. E. & Foulkes, W. D., Mar 2011, In: European Journal of Human Genetics. 19, 3, p. 300-306 7 p.

    Research output: Contribution to journalArticlepeer-review

    64 Scopus citations
  • Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers

    the Hereditary Breast Cancer Clinical Study Group, Jun 15 2019, In: Breast Cancer Research and Treatment. 175, 2, p. 443-449 7 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

    Narod, S. A., Dubé, M. P., Klijn, J., Lubinski, J., Lynch, H. T., Ghadirian, P., Provencher, D., Heimdal, K., Moller, P., Robson, M., Offit, K., Isaacs, C., Weber, B., Friedman, E., Gershoni-Baruch, R., Rennert, G., Pasini, B., Wagner, T., Daly, M., Garber, J. E., & 18 othersNeuhausen, S. L., Ainsworth, P., Olsson, H., Evans, G., Osborne, M., Couch, F., Foulkes, W. D., Warner, E., Kim-Sing, C., Olopade, O., Tung, N., Saal, H. M., Weitzel, J., Merajver, S., Gauthier-Villars, M., Jernstrom, H., Sun, P. & Brunet, J. S., Dec 4 2002, In: Journal of the National Cancer Institute. 94, 23, p. 1773-1779 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    296 Scopus citations
  • Ovarian and Breast Cancer Risks Associated with Pathogenic Variants in RAD51C and RAD51D

    Yang, X., Song, H., Leslie, G., Engel, C., Hahnen, E., Auber, B., Horváth, J., Kast, K., Niederacher, DI., Turnbull, C., Houlston, R., Hanson, H., Loveday, C., Dolinsky, J. S., Laduca, H., Ramus, S. J., Menon, U., Rosenthal, A. N., Jacobs, I., Gayther, S. A., & 41 othersDIcks, E., Nevanlinna, H., Aittomäki, K., Pelttari, L. M., Ehrencrona, H., Borg, Å., Kvist, A., Rivera, B., Hansen, T. V. O., Djursby, M., Lee, A., Dennis, J., Bowtell, D. D., Traficante, N., DIez, O., Balmaña, J., Gruber, S. B., Chenevix-Trench, G., Investigators, K., Jensen, A., Kjær, S. K., Høgdall, E., Castéra, L., Garber, J., Janavicius, R., Osorio, A., Golmard, L., Vega, A., Couch, F. J., Robson, M., Gronwald, J., Domchek, S. M., Culver, J. O., De La Hoya, M., Easton, D. F., Foulkes, W. D., Tischkowitz, M., Meindl, A., Schmutzler, R. K., Pharoah, P. D. P. & Antoniou, A. C., Dec 1 2020, In: Journal of the National Cancer Institute. 112, 12, p. 1242-1250 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

    OCGN, on behalf of the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA), SWE-BRCA, HEBON, EMBRACE, GEMO & KConFab, Apr 1 2012, In: Human mutation. 33, 4, p. 690-702 13 p.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • p53 mediates repression of the BRCA2 promoter and down-regulation of BRCA2 mRNA and protein levels in response to DNA damage

    Wu, K., Jiang, S. W. & Couch, F. J., May 2 2003, In: Journal of Biological Chemistry. 278, 18, p. 15652-15660 9 p.

    Research output: Contribution to journalArticlepeer-review

    37 Scopus citations
  • p73 mutations are not detected in sporadic and hereditary breast cancer

    Schwartz, D. I., Lindor, N. M., Walsh-Vockley, C., Roche, P. C., Ming, M., Smith, D. I., Wanguo, L. & Couch, F. J., Dec 1 1999, In: Breast Cancer Research and Treatment. 58, 1, p. 25-29 5 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • PALB2, CHEK2 and ATM rare variants and cancer risk: Data from COGS

    kConFab Investigators66 & Australian Ovarian Cancer Study Group65,66, Dec 1 2016, In: Journal of medical genetics. 53, 12, p. 800-811 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    106 Scopus citations
  • Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

    Perry, J. R. B., Day, F., Elks, C. E., Sulem, P., Thompson, D. J., Ferreira, T., He, C., Chasman, D. I., Esko, T., Thorleifsson, G., Albrecht, E., Ang, W. Q., Corre, T., Cousminer, D. L., Feenstra, B., Franceschini, N., Ganna, A., Johnson, A. D., Kjellqvist, S., Lunetta, K. L., & 178 othersMcMahon, G., Nolte, I. M., Paternoster, L., Porcu, E., Smith, A. V., Stolk, L., Teumer, A., Tšernikova, N., Tikkanen, E., Ulivi, S., Wagner, E. K., Amin, N., Bierut, L. J., Byrne, E. M., Hottenga, J. J., Koller, D. L., Mangino, M., Pers, T. H., Yerges-Armstrong, L. M., Zhao, J. H., Andrulis, I. L., Anton-Culver, H., Atsma, F., Bandinelli, S., Beckmann, M. W., Benitez, J., Blomqvist, C., Bojesen, S. E., Bolla, M. K., Bonanni, B., Brauch, H., Brenner, H., Buring, J. E., Chang-Claude, J., Chanock, S., Chen, J., Chenevix-Trench, G., Collée, J. M., Couch, F. J., Couper, D., Coviello, A. D., Cox, A., Czene, K., D'adamo, A. P., Smith, G. D., De Vivo, I., Demerath, E. W., Dennis, J., Devilee, P., Dieffenbach, A. K., Dunning, A. M., Eiriksdottir, G., Eriksson, J. G., Fasching, P. A., Ferrucci, L., Flesch-Janys, D., Flyger, H., Foroud, T., Franke, L., Garcia, M. E., García-Closas, M., Geller, F., De Geus, E. E. J., Giles, G. G., Gudbjartsson, D. F., Gudnason, V., Guénel, P., Guo, S., Hall, P., Hamann, U., Haring, R., Hartman, C. A., Heath, A. C., Hofman, A., Hooning, M. J., Hopper, J. L., Hu, F. B., Hunter, D. J., Karasik, D., Kiel, D. P., Knight, J. A., Kosma, V. M., Kutalik, Z., Lai, S., Lambrechts, D., Lindblom, A., Mägi, R., Magnusson, P. K., Mannermaa, A., Martin, N. G., Masson, G., McArdle, P. F., McArdle, W. L., Melbye, M., Michailidou, K., Mihailov, E., Milani, L., Milne, R. L., Nevanlinna, H., Neven, P., Nohr, E. A., Oldehinkel, A. J., Oostra, B. A., Palotie, A., Peacock, M., Pedersen, N. L., Peterlongo, P., Peto, J., Pharoah, P. D. P., Postma, D. S., Pouta, A., Pylkäs, K., Radice, P., Ring, S., Rivadeneira, F., Robino, A., Rose, L. M., Rudolph, A., Salomaa, V., Sanna, S., Schlessinger, D., Schmidt, M. K., Southey, M. C., Sovio, U., Stampfer, M. J., Stöckl, D., Storniolo, A. M., Timpson, N. J., Tyrer, J., Visser, J. A., Vollenweider, P., Völzke, H., Waeber, G., Waldenberger, M., Wallaschofski, H., Wang, Q., Willemsen, G., Winqvist, R., Wolffenbuttel, B. H. R., Wright, M. J., Boomsma, D. I., Econs, M. J., Khaw, K. T., Loos, R. J. F., McCarthy, M. I., Montgomery, G. W., Rice, J. P., Streeten, E. A., Thorsteinsdottir, U., Van Duijn, C. M., Alizadeh, B. Z., Bergmann, S., Boerwinkle, E., Boyd, H. A., Crisponi, L., Gasparini, P., Gieger, C., Harris, T. B., Ingelsson, E., Järvelin, M. R., Kraft, P., Lawlor, D., Metspalu, A., Pennell, C. E., Ridker, P. M., Snieder, H., Sørensen, T. I. A., Spector, T. D., Strachan, D. P., Uitterlinden, A. G., Wareham, N. J., Widen, E., Zygmunt, M., Murray, A., Easton, D. F., Stefansson, K., Murabito, J. M. & Ong, K. K., Oct 2 2014, In: Nature. 514, 7520, p. 92-97 6 p.

    Research output: Contribution to journalArticlepeer-review

    302 Scopus citations
  • Pathogenic variants in cancer predisposition genes and prostate cancer risk in men of african ancestry

    Matejcic, M., Patel, Y., Lilyquist, J., Hu, C., Lee, K. Y., Gnanaolivu, R. D., Hart, S. N., Polley, E. C., Yadav, S., Boddicker, N. J., Samara, R., Xia, L., Sheng, X., Lubmawa, A., Kiddu, V., Masaba, B., Namuguzi, D., Mutema, G., Job, K., Dabanja, H. M., & 7 othersIngles, S. A., Wilkens, L., Le Marchand, L., Watya, S., Couch, F. J., Conti, D. V. & Haiman, C. A., 2019, In: JCO Precision Oncology. 3, p. 32-43 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: Results from the consortium of investigators of modifiers of BRCA1/2 (CIMBA)

    Mavaddat, N., Barrowdale, D., Andrulis, I. L., Domchek, S. M., Eccles, D., Nevanlinna, H., Ramus, S. J., Spurdle, A., Robson, M., Sherman, M., Mulligan, A. M., Couch, F. J., Engel, C., McGuffog, L., Healey, S., Sinilnikova, O. M., Southey, M. C., Terry, M. B., Goldgar, D., O'Malley, F., & 113 othersJohn, E. M., Janavicius, R., Tihomirova, L., Hansen, T. V. O., Nielsen, F. C., Osorio, A., Stavropoulou, A., Benítez, J., Manoukian, S., Peissel, B., Barile, M., Volorio, S., Pasini, B., Dolcetti, R., Putignano, A. L., Ottini, L., Radice, P., Hamann, U., Rashid, M. U., Hogervorst, F. B., Kriege, M., Van Der Luijt, R. B., Peock, S., Frost, D., Evans, D. G., Brewer, C., Walker, L., Rogers, M. T., Side, L. E., Houghton, C., Weaver, J. E., Godwin, A. K., Schmutzler, R. K., Wappenschmidt, B., Meindl, A., Kast, K., Arnold, N., Niederacher, D., Sutter, C., Deissler, H., Gadzicki, D., Preisler-Adams, S., Varon-Mateeva, R., Schönbuchner, I., Gevensleben, H., Stoppa-Lyonnet, D., Belotti, M., Barjhoux, L., Isaacs, C., Peshkin, B. N., Caldes, T., De Al Hoya, M., Cañadas, C., Heikkinen, T., Heikkilä, P., Aittomäki, K., Blanco, I., Lazaro, C., Brunet, J., Agnarsson, B. A., Arason, A., Barkardottir, R. B., Dumont, M., Simard, J., Montagna, M., Agata, S., D'Andrea, E., Yan, M., Fox, S., Rebbeck, T. R., Rubinstein, W., Tung, N., Garber, J. E., Wang, X., Fredericksen, Z., Pankratz, V. S., Lindor, N. M., Szabo, C., Offit, K., Sakr, R., Gaudet, M. M., Singer, C. F., Tea, M. K., Rappaport, C., Mai, P. L., Greene, M. H., Sokolenko, A., Imyanitov, E., Toland, A. E., Senter, L., Sweet, K., Thomassen, M., Gerdes, A. M., Kruse, T., Caligo, M., Aretini, P., Rantala, J., Von Wachenfeld, A., Henriksson, K., Steele, L., Neuhausen, S. L., Nussbaum, R., Beattie, M., Odunsi, K., Sucheston, L., Gayther, S. A., Nathanson, K., Gross, J., Walsh, C., Karlan, B., Chenevix-Trench, G., Easton, D. F. & Antoniou, A. C., Jan 2012, In: Cancer Epidemiology Biomarkers and Prevention. 21, 1, p. 134-147 14 p.

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    338 Scopus citations
  • Patients' medical and psychosocial experiences after detection of a CDH1 variant with multigene panel testing

    Hamilton, J. G., Long, J. M., Brandt, A. C., Brower, J., Symecko, H., Salo-Mullen, E. E., Christian, S. N., Harstad, T., Couch, F. J., Garber, J. E., Offit, K., Robson, M. E. & Domchek, S. M., Jan 1 2019, In: JCO Precision Oncology. 3, p. 1-14 14 p.

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    11 Scopus citations
  • Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium

    Muranen, T. A., Blomqvist, C., Dörk, T., Jakubowska, A., Heikkilä, P., Fagerholm, R., Greco, D., Aittomäki, K., Bojesen, S. E., Shah, M., Dunning, A. M., Rhenius, V., Hall, P., Czene, K., Brand, J. S., Darabi, H., Chang-Claude, J., Rudolph, A., Nordestgaard, B. G., Couch, F. J., & 24 othersHart, S. N., Figueroa, J., García-Closas, M., Fasching, P. A., Beckmann, M. W., Li, J., Liu, J., Andrulis, I. L., Winqvist, R., Pylkäs, K., Mannermaa, A., Kataja, V., Lindblom, A., Margolin, S., Lubinski, J., Dubrowinskaja, N., Bolla, M. K., Dennis, J., Michailidou, K., Wang, Q., Easton, D. F., Pharoah, P. D. P., Schmidt, M. K. & Nevanlinna, H., Oct 3 2016, In: Breast Cancer Research. 18, 1, 98.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium

    Howat, W. J., Blows, F. M., Provenzano, E., Brook, M. N., Morris, L., Gazinska, P., Johnson, N., McDuffus, L. A., Miller, J., Sawyer, E. J., Pinder, S., van Deurzen, C. H. M., Jones, L., Sironen, R., Visscher, D., Caldas, C., Daley, F., Coulson, P., Broeks, A., Sanders, J., & 32 othersWesseling, J., Nevanlinna, H., Fagerholm, R., Blomqvist, C., Heikkilä, P., Ali, H. R., Dawson, S. J., Figueroa, J., Lissowska, J., Brinton, L., Mannermaa, A., Kataja, V., Kosma, V. M., Cox, A., Brock, I. W., Cross, S. S., Reed, M. W., Couch, F. J., Olson, J. E., Devillee, P., Mesker, W. E., Seyaneve, C. M., Hollestelle, A., Benitez, J., Perez, J. I. A., Menéndez, P., Bolla, M. K., Easton, D. F., Schmidt, M. K., Pharoah, P. D., Sherman, M. E. & García-Closas, M., Jan 2015, In: Journal of Pathology: Clinical Research. 1, 1, p. 18-32 15 p.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes

    Goetz, M. P., Rae, J. M., Suman, V. J., Safgren, S. L., Ames, M. M., Visscher, D. W., Reynolds, C., Couch, F. J., Lingle, W. L., Flockhart, D. A., Desta, Z., Perez, E. A. & Ingle, J. N., 2005, In: Journal of Clinical Oncology. 23, 36, p. 9312-9318 7 p.

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    679 Scopus citations
  • PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1

    Jiao, X., Aravidis, C., Marikkannu, R., Rantala, J., Picelli, S., Adamovic, T., Liu, T., Maguire, P., Kremeyer, B., Luo, L., von Holst, S., Kontham, V., Thutkawkorapin, J., Margolin, S., Du, Q., Lundin, J., Michailidou, K., Bolla, M. K., Wang, Q., Dennis, J., & 86 othersLush, M., Ambrosone, C. B., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Beckmann, M. W., Blomqvist, C., Blot, W., Boeckx, B., Bojesen, S. E., Bonanni, B., Brand, J. S., Brauch, H., Brenner, H., Broeks, A., Brüning, T., Burwinkel, B., Cai, Q., Chang-Claude, J., NBCS Collaborators, C., Couch, F. J., Cox, A., Cross, S. S., Deming-Halverson, S. L., Devilee, P., dos-Santos-Silva, I., Dörk, T., Eriksson, M., Fasching, P. A., Figueroa, J., Flesch-Janys, D., Flyger, H., Gabrielson, M., García-Closas, M., Giles, G. G., González-Neira, A., Guénel, P., Guo, Q., Gündert, M., Haiman, C. A., Hallberg, E., Hamann, U., Harrington, P., Hooning, M. J., Hopper, J. L., Huang, G., Jakubowska, A., Jones, M. E., Kerin, M. J., Kosma, V. M., Kristensen, V. N., Lambrechts, D., Marchand, L. L., Lubinski, J., Mannermaa, A., Martens, J. W. M., Meindl, A., Milne, R. L., Mulligan, A. M., Neuhausen, S. L., Nevanlinna, H., Peto, J., Pylkäs, K., Radice, P., Rhenius, V., Sawyer, E. J., Schmidt, M. K., Schmutzler, R. K., Seynaeve, C., Shah, M., Simard, J., Southey, M. C., Swerdlow, A. J., Truong, T., Wendt, C., Winqvist, R., Zheng, W., kConFab/AOCS Investigators, I., Benitez, J., Dunning, A. M., Pharoah, P. D. P., Easton, D. F., Czene, K., Hall, P. & Lindblom, A., 2017, In: Oncotarget. 8, 61, p. 102769-102782 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study

    Dixon-Suen, S. C., Lewis, S. J., Martin, R. M., English, D. R., Boyle, T., Giles, G. G., Michailidou, K., Bolla, M. K., Wang, Q., Dennis, J., Lush, M., Investigators, A., Ahearn, T. U., Ambrosone, C. B., Andrulis, I. L., Anton-Culver, H., Arndt, V., Aronson, K. J., Augustinsson, A., Auvinen, P., & 138 othersFreeman, L. E. B., Becher, H., Beckmann, M. W., Behrens, S., Bermisheva, M., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bonanni, B., Brenner, H., Brüning, T., Buys, S. S., Camp, N. J., Campa, D., Canzian, F., Castelao, J. E., Cessna, M. H., Chang-Claude, J., Chanock, S. J., Clarke, C. L., Conroy, D. M., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Devilee, P., Dörk, T., Dwek, M., Eccles, D. M., Eliassen, A. H., Engel, C., Eriksson, M., Evans, D. G., Fasching, P. A., Fletcher, O., Flyger, H., Fritschi, L., Gabrielson, M., Gago-Dominguez, M., García-Closas, M., García-Sáenz, J. A., Goldberg, M. S., Guénel, P., Gündert, M., Hahnen, E., Haiman, C. A., Häberle, L., Håkansson, N., Hall, P., Hamann, U., Hart, S. N., Harvie, M., Hillemanns, P., Hollestelle, A., Hooning, M. J., Hoppe, R., Hopper, J., Howell, A., Hunter, D. J., Jakubowska, A., Janni, W., John, E. M., Jung, A., Kaaks, R., Keeman, R., Kitahara, C. M., Koutros, S., Kraft, P., Kristensen, V. N., Kubelka-Sabit, K., Kurian, A. W., Lacey, J. V., Lambrechts, D., Le Marchand, L., Lindblom, A., Loibl, S., Lubiński, J., Mannermaa, A., Manoochehri, M., Margolin, S., Martinez, M. E., Mavroudis, D., Menon, U., Mulligan, A. M., Murphy, R. A., Collaborators, N., Nevanlinna, H., Nevelsteen, I., Newman, W. G., Offit, K., Olshan, A. F., Olsson, H., Orr, N., Patel, A., Peto, J., Plaseska-Karanfilska, D., Presneau, N., Rack, B., Radice, P., Rees-Punia, E., Rennert, G., Rennert, H. S., Romero, A., Saloustros, E., Sandler, D. P., Schmidt, M. K., Schmutzler, R. K., Schwentner, L., Scott, C., Shah, M., Shu, X. O., Simard, J., Southey, M. C., Stone, J., Surowy, H., Swerdlow, A. J., Tamimi, R. M., Tapper, W. J., Taylor, J. A., Terry, M. B., Tollenaar, R. A. E. M., Troester, M. A., Truong, T., Untch, M., Vachon, C. M., Joseph, V., Wappenschmidt, B., Weinberg, C. R., Wolk, A., Yannoukakos, D., Zheng, W., Ziogas, A., Dunning, A. M., Pharoah, P. D. P., Easton, D. F., Milne, R. L. & Lynch, B. M., Sep 6 2022, In: British journal of sports medicine. 56, 20, p. 1157-1170 14 p.

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  • Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo

    Sinha, S., Pal, K., Elkhanany, A., Dutta, S., Cao, Y., Mondal, G., Iyer, S., Somasundaram, V., Couch, F. J., Shridhar, V., Bhattacharya, R., Mukhopadhyay, D. & Srinivas, P., Mar 1 2013, In: International Journal of Cancer. 132, 5, p. 1201-1212 12 p.

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    80 Scopus citations
  • Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter

    Wang, J., Bian, C., Li, J., Couch, F. J., Wu, K. & Zhao, R. C., Dec 26 2008, In: Journal of Biological Chemistry. 283, 52, p. 36249-36256 8 p.

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    21 Scopus citations
  • Polygenic risk modeling for prediction of epithelial ovarian cancer risk

    GEMO Study Collaborators, GC-HBOC Study Collaborators, EMBRACE Collaborators, OPAL study group, AOCS Group, KConFab investigators, HEBON Investigators, The OCAC Consortium & the Cimba Consortium, Mar 2022, In: European Journal of Human Genetics. 30, 3, p. 349-362 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

    the Consortium of Investigators of Modifiers of BRCA and BRCA2, Oct 1 2020, In: Genetics in Medicine. 22, 10, p. 1653-1666 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    NBCS Collaborators, ABCTB Investigators & kConFab/AOCS Investigators, Jan 3 2019, In: American journal of human genetics. 104, 1, p. 21-34 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    202 Scopus citations
  • Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk

    McWilliams, R. R., Bamlet, W. R., De Andrade, M., Rider, D. N., Couch, F. J., Cunningham, J. M., Matsumoto, M. E., Rabe, K. G., Hammer, T. J. & Petersen, G. M., Sep 2009, In: Cancer Epidemiology Biomarkers and Prevention. 18, 9, p. 2549-2552 4 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

    Darabi, H., McCue, K., Beesley, J., Michailidou, K., Nord, S., Kar, S., Humphreys, K., Thompson, D., Ghoussaini, M., Bolla, M. K., Dennis, J., Wang, Q., Canisius, S., Scott, C. G., Apicella, C., Hopper, J. L., Southey, M. C., Stone, J., Broeks, A., Schmidt, M. K., & 109 othersScott, R. J., Lophatananon, A., Muir, K., Beckmann, M. W., Ekici, A. B., Fasching, P. A., Heusinger, K., Dos-Santos-Silva, I., Peto, J., Tomlinson, I., Sawyer, E. J., Burwinkel, B., Marme, F., Guénel, P., Truong, T., Bojesen, S. E., Flyger, H., Benitez, J., González-Neira, A., Anton-Culver, H., Neuhausen, S. L., Arndt, V., Brenner, H., Engel, C., Meindl, A., Schmutzler, R. K., Arnold, N., Brauch, H., Hamann, U., Chang-Claude, J., Khan, S., Nevanlinna, H., Ito, H., Matsuo, K., Bogdanova, N. V., Dörk, T., Lindblom, A., Margolin, S., Kosma, V. M., Mannermaa, A., Tseng, C. C., Wu, A. H., Floris, G., Lambrechts, D., Rudolph, A., Peterlongo, P., Radice, P., Couch, F. J., Vachon, C., Giles, G. G., McLean, C., Milne, R. L., Dugué, P. A., Haiman, C. A., Maskarinec, G., Woolcott, C., Henderson, B. E., Goldberg, M. S., Simard, J., Teo, S. H., Mariapun, S., Helland, Å., Haakensen, V., Zheng, W., Beeghly-Fadiel, A., Tamimi, R., Jukkola-Vuorinen, A., Winqvist, R., Andrulis, I. L., Knight, J. A., Devilee, P., Tollenaar, R. A. E. M., Figueroa, J., García-Closas, M., Czene, K., Hooning, M. J., Tilanus-Linthorst, M., Li, J., Gao, Y. T., Shu, X. O., Cox, A., Cross, S. S., Luben, R., Khaw, K. T., Choi, J. Y., Kang, D., Hartman, M., Lim, W. Y., Kabisch, M., Torres, D., Jakubowska, A., Lubinski, J., McKay, J., Sangrajrang, S., Toland, A. E., Yannoukakos, D., Shen, C. Y., Yu, J. C., Ziogas, A., Schoemaker, M. J., Swerdlow, A., Borresen-Dale, A. L., Kristensen, V., French, J. D., Edwards, S. L., Dunning, A. M., Easton, D. F., Hall, P. & Chenevix-Trench, G., 2015, In: American journal of human genetics. 97, 1, p. 22-34 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    22 Scopus citations
  • Polymorphisms in PTEN in breast cancer families

    Carroll, B. T., Couch, F. J., Rebbeck, T. R. & Weber, B. L., 1999, In: Journal of medical genetics. 36, 2, p. 94-96 3 p.

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    37 Scopus citations
  • PP2A and E3 ubiquitin ligase deficiencies: Seminal biological drivers in endometrial cancer

    Gonzalez-Bosquet, J., Bakkum-Gamez, J. N., Weaver, A. L., McGree, M. E., Dowdy, S. C., Famuyide, A. O., Kipp, B. R., Halling, K. C., Couch, F. J. & Podratz, K. C., Jul 2021, In: Gynecologic oncology. 162, 1, p. 182-189 8 p.

    Research output: Contribution to journalArticlepeer-review

  • Predicting BRCA1 and BRCA2 gene mutation carriers: Comparison of PENN II model to previous study

    Lindor, N. M., Johnson, K. J., Harvey, H., Shane Pankratz, V., Domchek, S. M., Hunt, K., Wilson, M., Cathie Smith, M. & Couch, F., Dec 2010, In: Familial Cancer. 9, 4, p. 495-502 8 p.

    Research output: Contribution to journalArticlepeer-review

    31 Scopus citations
  • Prediction of breast and prostate cancer risks in male BRCA1 and BRCA2 mutation carriers using polygenic risk scores

    Lecarpentier, J., Kuchenbaecker, K. B., Barrowdale, D., Dennis, J., McGuffog, L., Leslie, G., Lee, A., Al Olama, A. A., Tyrer, J. P., Frost, D., Ellis, S., Easton, D. F., Antoniou, A. C., Tischkowitz, M., Evans, D. G., Henderson, A., Brewer, C., Eccles, D., Cook, J., Ong, K. R., & 157 othersWalker, L., Side, L. E., Hodgson, S., Izatt, L., Eeles, R., Orr, N., Porteous, M. E., Davidson, R., Adlard, J., Silvestri, V., Rizzolo, P., Navazio, A. S., Valentini, V., Zelli, V., Ottini, L., Toss, A., Medici, V., Cortesi, L., Zanna, I., Palli, D., Radice, P., Manoukian, S., Peissel, B., Azzollini, J., Peterlongo, P., Viel, A., Cini, G., Damante, G., Tommasi, S., Alducci, E., Tognazzo, S., Montagna, M., Caligo, M. A., Soucy, P., Simard, J., Mulligan, A. M., Andrulis, I. L., Glendon, G., Southey, M., Campbell, I., James, P., Mitchell, G., Spurdle, A. B., Holland, H., Chenevix-Trench, G., John, E. M., Steele, L., Ding, Y. C., Neuhausen, S. L., Weitzel, J. N., Conner, T. A., Buys, S. S., Goldgar, D. E., Godwin, A. K., Sharma, P., Rebbeck, T. R., Vijai, J., Robson, M., Lincoln, A., Musinsky, J., Gaddam, P., Offit, K., Loud, J. T., Greene, M. H., Toland, A. E., Senter, L., Huo, D., Nielsen, S. M., Olopade, O. I., Nathanson, K. L., Domchek, S. M., Lorenchick, C., Jankowitz, R. C., Couch, F. J., Janavicius, R., Hansen, T. V. O., Bojesen, A., Nielsen, H. R., Skytte, A. B., Sunde, L., Jensen, U. B., Pedersen, I. S., Krogh, L., Kruse, T. A., Thomassen, M., Osorio, A., De La Hoya, M., Garcia-Barberan, V., Caldes, T., Segura, P. P., Balmaña, J., Gutiérrez-Enríquez, S., Diez, O., Teulé, A., Del Valle, J., Feliubadalo, L., Pujana, M. A., Lazaro, C., Izquierdo, A., Darder, E., Brunet, J., Fostira, F., Hamann, U., Sutter, C., Meindl, A., Ditsch, N., Gehrig, A., Dworniczak, B., Engel, C., Wand, D., Niederacher, D., Steinemann, D., Hahnen, E., Hauke, J., Rhiem, K., Wappenschmidt, B., Schmutzler, R. K., Kast, K., Arnold, N., Wang-Gohrke, S., Lasset, C., Damiola, F., Barjhoux, L., Mazoyer, S., Stoppa-Lyonnet, D., Belotti, M., Van Heetvelde, M., Poppe, B., De Leeneer, K., Claes, K. B. M., Kiiski, J. I., Khan, S., Nevanlinna, H., Aittomaki, K., Vvan Asperen, C. J., Vaszko, T., Kasler, M., Olah, E., Arason, A., Agnarsson, B. A., Johannsson, O. T., Barkardottir, R. B., Teixeira, M. R., Pinto, P., Lee, J. W., Lee, M. H., Lee, J., Kim, S. W., Kang, E., Park, S. K., Kim, Z., Tan, Y. Y., Berger, A., Singer, C. F., Yoon, S. Y., Teo, S. H. & Von Wachenfeldt, A., Jul 10 2017, In: Journal of Clinical Oncology. 35, 20, p. 2240-2250 11 p.

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    Open Access
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  • Prediction of breast cancer risk based on profiling with common genetic variants

    Mavaddat, N., Pharoah, P. D. P., Michailidou, K., Tyrer, J., Brook, M. N., Bolla, M. K., Wang, Q., Dennis, J., Dunning, A. M., Shah, M., Luben, R., Brown, J., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Czene, K., Darabi, H., Eriksson, M., Peto, J., & 192 othersDos-Santos-Silva, I., Dudbridge, F., Johnson, N., Schmidt, M. K., Broeks, A., Verhoef, S., Rutgers, E. J., Swerdlow, A., Ashworth, A., Orr, N., Schoemaker, M. J., Figueroa, J., Chanock, S. J., Brinton, L., Lissowska, J., Couch, F. J., Olson, J. E., Vachon, C., Pankratz, V. S., Lambrechts, D., Wildiers, H., Van Ongeval, C., Van Limbergen, E., Kristensen, V., Grenaker Alnæs, G., Nord, S., Borresen-Dale, A. L., Nevanlinna, H., Muranen, T. A., Aittomäki, K., Blomqvist, C., Chang-Claude, J., Rudolph, A., Seibold, P., Flesch-Janys, D., Fasching, P. A., Haeberle, L., Ekici, A. B., Beckmann, M. W., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Trentham-Dietz, A., Newcomb, P., Titus, L., Egan, K. M., Hunter, D. J., Lindstrom, S., Tamimi, R. M., Kraft, P., Rahman, N., Turnbull, C., Renwick, A., Seal, S., Li, J., Liu, J., Humphreys, K., Benitez, J., Pilar Zamora, M., Arias Perez, J. I., Menéndez, P., Jakubowska, A., Lubinski, J., Jaworska-Bieniek, K., Durda, K., Bogdanova, N. V., Antonenkova, N. N., Dörk, T., Anton-Culver, H., Neuhausen, S. L., Ziogas, A., Bernstein, L., Devilee, P., Tollenaar, R. A. E. M., Seynaeve, C., Van Asperen, C. J., Cox, A., Cross, S. S., Reed, M. W. R., Khusnutdinova, E., Bermisheva, M., Prokofyeva, D., Takhirova, Z., Meindl, A., Schmutzler, R. K., Sutter, C., Yang, R., Schürmann, P., Bremer, M., Christiansen, H., Park-Simon, T. W., Hillemanns, P., Guénel, P., Truong, T., Menegaux, F., Sanchez, M., Radice, P., Peterlongo, P., Manoukian, S., Pensotti, V., Hopper, J. L., Tsimiklis, H., Apicella, C., Southey, M. C., Brauch, H., Brüning, T., Ko, Y. D., Sigurdson, A. J., Doody, M. M., Hamann, U., Torres, D., Ulmer, H. U., Försti, A., Sawyer, E. J., Tomlinson, I., Kerin, M. J., Miller, N., Andrulis, I. L., Knight, J. A., Glendon, G., Marie Mulligan, A., Chenevix-Trench, G., Balleine, R., Giles, G. G., Milne, R. L., McLean, C., Lindblom, A., Margolin, S., Haiman, C. A., Henderson, B. E., Schumacher, F., Le Marchand, L., Eilber, U., Wang-Gohrke, S., Hooning, M. J., Hollestelle, A., Van Den Ouweland, A. M. W., Koppert, L. B., Carpenter, J., Clarke, C., Scott, R., Mannermaa, A., Kataja, V., Kosma, V. M., Hartikainen, J. M., Brenner, H., Arndt, V., Stegmaier, C., Karina Dieffenbach, A., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Offit, K., Vijai, J., Robson, M., Rau-Murthy, R., Dwek, M., Swann, R., Annie Perkins, K., Goldberg, M. S., Labrèche, F., Dumont, M., Eccles, D. M., Tapper, W. J., Rafiq, S., John, E. M., Whittemore, A. S., Slager, S., Yannoukakos, D., Toland, A. E., Yao, S., Zheng, W., Halverson, S. L., González-Neira, A., Pita, G., Rosario Alonso, M., Álvarez, N., Herrero, D., Tessier, D. C., Vincent, D., Bacot, F., Luccarini, C., Baynes, C., Ahmed, S., Maranian, M., Healey, C. S., Simard, J., Hall, P., Easton, D. F. & Garcia-Closas, M., May 1 2015, In: Journal of the National Cancer Institute. 107, 5

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  • Prediction of the functional impact of missense variants in BRCA1 and BRCA2 with BRCA-ML

    Hart, S. N., Polley, E. C., Shimelis, H., Yadav, S. & Couch, F. J., Dec 1 2020, In: npj Breast Cancer. 6, 1, 13.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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  • PREDICT Plus: Development and validation of a prognostic model for early breast cancer that includes HER2

    Wishart, G. C., Bajdik, C. D., Dicks, E., Provenzano, E., Schmidt, M. K., Sherman, M., Greenberg, D. C., Green, A. R., Gelmon, K. A., Kosma, V. M., Olson, J. E., Beckmann, M. W., Winqvist, R., Cross, S. S., Severi, G., Huntsman, D., Pylkäs, K., Ellis, I., Nielsen, T. O., Giles, G., & 17 othersBlomqvist, C., Fasching, P. A., Couch, F. J., Rakha, E., Foulkes, W. D., Blows, F. M., Bégin, L. R., Van'T Veer, L. J., Southey, M., Nevanlinna, H., Mannermaa, A., Cox, A., Cheang, M., Baglietto, L., Caldas, C., Garcia-Closas, M. & Pharoah, P. D. P., Aug 21 2012, In: British journal of cancer. 107, 5, p. 800-807 8 p.

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    104 Scopus citations
  • Prevalence of pathogenic mutations in cancer predisposition genes among pancreatic cancer patients

    Hu, C., Hart, S. N., Bamlet, W. R., Moore, R. M., Nandakumar, K., Eckloff, B. W., Lee, Y. K., Petersen, G. M., McWilliams, R. R. & Couch, F. J., Jan 2016, In: Cancer Epidemiology Biomarkers and Prevention. 25, 1, p. 207-211 5 p.

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  • Prognostic value of automated KI67 scoring in breast cancer: A centralised evaluation of 8088 patients from 10 study groups

    Abubakar, M., Orr, N., Daley, F., Coulson, P., Ali, H. R., Blows, F., Benitez, J., Milne, R., Brenner, H., Stegmaier, C., Mannermaa, A., Chang-Claude, J., Rudolph, A., Sinn, P., Couch, F. J., Devilee, P., Tollenaar, R. A. E. M., Seynaeve, C., Figueroa, J., Sherman, M. E., & 21 othersLissowska, J., Hewitt, S., Eccles, D., Hooning, M. J., Hollestelle, A., Martens, J. W. M., Deurzen, C. H. M., Investigators, K. C. F., Bolla, M. K., Wang, Q., Jones, M., Schoemaker, M., Wesseling, J., van Leeuwen, F. E., Van 't Veer, L., Easton, D., Swerdlow, A. J., Dowsett, M., Pharoah, P. D., Schmidt, M. K. & Garcia-Closas, M., Oct 18 2016, In: Breast Cancer Research. 18, 1, 104.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    40 Scopus citations
  • Progress toward isolation of a breast cancer susceptibility gene, BRCA1

    Weber, B. L., Abel, K. J., Couch, F. J., Merajver, S. D., Chandrasekharappa, S. C., Castilla, L., McKinley, D., Ho, P. P., Calzone, K., Frank, T. S., Xu, J., Brody, L. C. & Collins, F. S., 1994, In: Cold Spring Harbor Symposia on Quantitative Biology. 59, p. 531-536 6 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
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