Projects per year
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Dive into the research topics where Eugenia D Trushina is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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AMP-Kinase as a target for neuroprotection in AD
Project: Research project
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Small molecule mitochondria-targeted therapeutics for Huntingtons Disease
Project: Research project
Research output
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A genome-wide association study in human lymphoblastoid cells supports safety of mitochondrial complex I inhibitor
Gao, H., Tripathi, U., Trushin, S., Okromelidze, L., Pichurin, N. P., Wei, L., Zhuang, Y., Wang, L. & Trushina, E., May 2021, In: Mitochondrion. 58, p. 83-94 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice
Stojakovic, A., Trushin, S., Sheu, A., Khalili, L., Chang, S. Y., Li, X., Christensen, T., Salisbury, J. L., Geroux, R. E., Gateno, B., Flannery, P. J., Dehankar, M., Funk, C. C., Wilkins, J., Stepanova, A., O’Hagan, T., Galkin, A., Nesbitt, J., Zhu, X., Tripathi, U. & 16 others, , Dec 2021, In: Communications Biology. 4, 1, 61.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Partial Inhibition of Mitochondrial Complex i Reduces Tau Pathology and Improves Energy Homeostasis and Synaptic Function in 3xTg-AD Mice
Stojakovic, A., Chang, S. Y., Nesbitt, J., Pichurin, N. P., Ostroot, M. A., Aikawa, T., Kanekiyo, T. & Trushina, E., 2021, In: Journal of Alzheimer's Disease. 79, 1, p. 335-353 19 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
Cunnane, S. C., Trushina, E., Morland, C., Prigione, A., Casadesus, G., Andrews, Z. B., Beal, M. F., Bergersen, L. H., Brinton, R. D., de la Monte, S., Eckert, A., Harvey, J., Jeggo, R., Jhamandas, J. H., Kann, O., la Cour, C. M., Martin, W. F., Mithieux, G., Moreira, P. I., Murphy, M. P. & 7 others, , Sep 1 2020, In: Nature Reviews Drug Discovery. 19, 9, p. 609-633 25 p.Research output: Contribution to journal › Review article › peer-review
43 Scopus citations -
Changes in PGC‐1α/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model
Panes, J. D., Godoy, P. A., Silva-Grecchi, T., Celis, M. T., Ramirez-Molina, O., Gavilan, J., Muñoz-Montecino, C., Castro, P. A., Moraga-Cid, G., Yévenes, G. E., Guzmán, L., Salisbury, J. L., Trushina, E. & Fuentealba, J., May 21 2020, In: Frontiers in Pharmacology. 11, 709.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations