• 9154 Citations
  • 48 Scopus h-Index
1971 …2020

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Article
2012

SAAP-RRBS: Streamlined analysis and annotation pipeline for reduced representation bisulfite sequencing

Sun, Z., Baheti, S., Middha, S., Kanwar, R., Zhang, Y., Li, X., Beutler, A. S., Klee, E., Asmann, Y. W., Thompson, E. A. & Kocher, J. P. A., Aug 2012, In : Bioinformatics. 28, 16, p. 2180-2181 2 p., bts337.

Research output: Contribution to journalArticle

33 Scopus citations
2011

A novel bioinformatics pipeline for identification and characterization of fusion transcripts in breast cancer and normal cell lines

Asmann, Y. W., Hossain, A., Necela, B. M., Middha, S., Kalari, K. R., Sun, Z., Chai, H. S., Williamson, D. W., Radisky, D., Schroth, G. P., Kocher, J. P. A., Perez, E. A. & Thompson, E. A., Aug 2011, In : Nucleic acids research. 39, 15, p. e100

Research output: Contribution to journalArticle

69 Scopus citations

Differential expression of microRNAs in tumors from chronically inflamed or genetic (APCmin/+) models of colon cancer

Necela, B. M., Carr, J. M., Asmann, Y. W. & Thompson, E. A., 2011, In : PloS one. 6, 4, e18501.

Research output: Contribution to journalArticle

49 Scopus citations

Integrated analysis of gene expression, CpG Island methylation, and gene copy number in breast cancer cells by deep sequencing

Sun, Z., Asmann, Y. W., Kalari, K. R., Bot, B., Eckel-Passow, J. E., Baker, T. R., Carr, J. M., Khrebtukova, I., Luo, S., Zhang, L., Schroth, G. P., Perez, E. A. & Thompson, E. A., 2011, In : PloS one. 6, 2, e17490.

Research output: Contribution to journalArticle

111 Scopus citations
2009
Open Access
123 Scopus citations

Meta-analysis of oncogenic protein kinase Cι signaling in lung adenocarcinoma

Erdogan, E., Klee, E. W., Thompson, E. A. & Fields, A. P., Mar 1 2009, In : Clinical Cancer Research. 15, 5, p. 1527-1533 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Prokineticin 1 modulates IL-8 expression via the calcineurin/NFAT signaling pathway

Maldonado-Pérez, D., Brown, P., Morgan, K., Millar, R. P., Thompson, E. A. & Jabbour, H. N., Jul 1 2009, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1793, 7, p. 1315-1324 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Prostaglandin F-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway

Sales, K. J., Maldonado-Pérez, D., Grant, V., Catalano, R. D., Wilson, M. R., Brown, P., Williams, A. R. W., Anderson, R. A., Thompson, E. A. & Jabbour, H. N., Dec 2009, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1793, 12, p. 1917-1928 12 p.

Research output: Contribution to journalArticle

40 Scopus citations

TGF-β repression of Id2 induces apoptosis in gut epithelial cells

Cao, Y., Liu, X., Zhang, W., Deng, X., Zhang, H., Liu, Y., Chen, L., Thompson, E. A., Townsend, C. M. & Ko, T. C., Feb 26 2009, In : Oncogene. 28, 8, p. 1089-1098 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2008

Atypical protein kinase Cι expression and aurothiomalate sensitivity in human lung cancer cells

Regala, R. P., Thompson, E. A. & Fields, A. P., Jul 15 2008, In : Cancer research. 68, 14, p. 5888-5895 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Matrix metalloproteinase-10 is a critical effector of protein kinase Cι-Par6α-mediated lung cancer

Frederick, L. A., Matthews, J. A., Jamieson, L., Justilien, V., Thompson, E. A., Radisky, D. C. & Fields, A. P., Aug 14 2008, In : Oncogene. 27, 35, p. 4841-4853 13 p.

Research output: Contribution to journalArticle

67 Scopus citations

Oncogenic K-ras promotes early carcinogenesis in the mouse proximal colon

Calcagno, S. R., Li, S., Colon, M., Kreinest, P. A., Thompson, E. A., Fields, A. P. & Murray, N. R., Jun 1 2008, In : International Journal of Cancer. 122, 11, p. 2462-2470 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Peroxisome proliferator-activated receptor γ down-regulates follistatin in intestinal epithelial cells through SP1

Necela, B. M., Su, W. & Thompson, E. A., Oct 31 2008, In : Journal of Biological Chemistry. 283, 44, p. 29784-29794 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
12 Scopus citations

Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in macrophages

Necela, B. M., Su, W. & Thompson, E. A., Nov 1 2008, In : Immunology. 125, 3, p. 344-358 15 p.

Research output: Contribution to journalArticle

85 Scopus citations

Transcriptome Profiling Using Next-Generation Sequencing

Asmann, Y. W., Wallace, M. B. & Thompson, E. A., Nov 2008, In : Gastroenterology. 135, 5, p. 1466-1468 3 p.

Research output: Contribution to journalArticle

30 Scopus citations
2007

Differential expression, distribution, and function of PPAR-γ in the proximal and distal colon

Su, W., Bush, C. R., Necela, B. M., Calcagno, S. R., Murray, N. R., Fields, A. P. & Thompson, E. A., Aug 20 2007, In : Physiological Genomics. 30, 3, p. 342-353 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor γ and calcium signaling in human colorectal cancer cells

Bush, C. R., Havens, J. M., Necela, B. M., Su, W., Chen, L., Yanagisawa, M., Anastasiadis, P. Z., Guerra, R., Luxon, B. A. & Thompson, E. A., Aug 10 2007, In : Journal of Biological Chemistry. 282, 32, p. 23387-23401 15 p.

Research output: Contribution to journalArticle

22 Scopus citations

Identification of apoptotic genes mediating TGF-β/Smad3-induced cell death in intestinal epithelial cells using a genomic approach

Cao, Y., Chen, L., Zhang, W., Liu, Y., Papaconstantinou, H. T., Bush, C. R., Townsend, C. M., Thompson, E. A. & Ko, T. C., Jan 1 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 292, 1, p. G28-G38

Research output: Contribution to journalArticle

20 Scopus citations
2006

Aurothiomalate inhibits transformed growth by targeting the PB1 domain of protein kinase Ci

Erdogan, E., Lamark, T., Stallings-Mann, M., Jamieson, L., Pellechia, M., Aubrey Thompson, E., Johansen, T. & Fields, A. P., Sep 22 2006, In : Journal of Biological Chemistry. 281, 38, p. 28450-28459 10 p.

Research output: Contribution to journalArticle

75 Scopus citations

Evi1 is a survival factor which conveys resistance to both TGFβ- and taxol-mediated cell death via PI3K/AKT

Liu, Y., Chen, L., Ko, T. C., Fields, A. P. & Thompson, E. A., Jun 15 2006, In : Oncogene. 25, 25, p. 3565-3575 11 p.

Research output: Contribution to journalArticle

75 Scopus citations

Peroxisome proliferator-activated receptor γ promotes epithelial to mesenchymal transformation by Rho GTPase-dependent activation of ERK1/2

Chen, L., Necela, B. M., Su, W., Yanagisawa, M., Anastasiadis, P. Z., Fields, A. P. & Thompson, E. A., Aug 25 2006, In : Journal of Biological Chemistry. 281, 34, p. 24575-24587 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

RS5444, a novel PPARγ agonist, regulates aspects of the differentiated phenotype in nontransformed intestinal epithelial cells

Chen, L., Bush, C. R., Necela, B. M., Su, W., Yanagisawa, M., Anastasiadis, P. Z., Fields, A. P. & Thompson, E. A., Jun 7 2006, In : Molecular and Cellular Endocrinology. 251, 1-2, p. 17-32 16 p.

Research output: Contribution to journalArticle

28 Scopus citations
2005

Atypical protein kinase Cτ plays a critical role in human lung cancer cell growth and tumorigenicity

Regala, R. P., Weems, C., Jamieson, L., Copland, J. A., Thompson, E. A. & Fields, A. P., Sep 2 2005, In : Journal of Biological Chemistry. 280, 35, p. 31109-31115 7 p.

Research output: Contribution to journalArticle

154 Scopus citations
2004

Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis

Conery, A. R., Cao, Y., Thompson, E. A., Townsend, C. M., Ko, T. C. & Luo, K., Apr 1 2004, In : Nature Cell Biology. 6, 4, p. 366-372 7 p.

Research output: Contribution to journalArticle

290 Scopus citations

Bcr-Abl Regulates Protein Kinase Cι (PKCι) Transcription via an Elk1 Site in the PKCι Promoter

Gustafson, W. C., Ray, S., Jamieson, L., Thompson, E. A., Brasier, A. R. & Fields, A. P., Mar 5 2004, In : Journal of Biological Chemistry. 279, 10, p. 9400-9408 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Protein kinase c (PKC) βII induces cell invasion through a Ras/Mek-, PKCι/Rac 1-dependent signaling pathway

Zhang, J., Anastasiadis, P. Z., Liu, Y., Thompson, E. A. & Fields, A. P., May 21 2004, In : Journal of Biological Chemistry. 279, 21, p. 22118-22123 6 p.

Research output: Contribution to journalArticle

117 Scopus citations

Protein kinase C beta;II regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo

Liu, Y., Su, W., Thompson, E. A., Leitges, M., Murray, N. R. & Fields, A. P., Oct 29 2004, In : Journal of Biological Chemistry. 279, 44, p. 45556-45563 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Protein kinase Cι is required for Ras transformation and colon carcinogenesis in vivo

Murray, N. R., Jamieson, L., Yu, W., Zhang, J., Gökmen-Polar, Y., Sier, D., Anastasiadis, P., Gatalica, Z., Thompson, E. A. & Fields, A. P., Mar 15 2004, In : Journal of Cell Biology. 164, 6, p. 797-802 6 p.

Research output: Contribution to journalArticle

113 Scopus citations
2003

Over-expression of cyclin D1 regulates Cdk4 protein synthesis

Parker, M. A., Deane, N. G., Thompson, E. A., Whitehead, R. H., Mithani, S. K., Washington, M. K., Datta, P. K., Dixon, D. A. & Beauchamp, R. D., Dec 1 2003, In : Cell Proliferation. 36, 6, p. 347-360 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Role of cyclooxygenase 2 in protein kinase C βII-mediated colon carcinogenesis

Yu, W., Murray, N. R., Weems, C., Chen, L., Guo, H., Ethridge, R., Ceci, J. D., Evers, B. M., Thompson, E. A. & Fields, A. P., Mar 28 2003, In : Journal of Biological Chemistry. 278, 13, p. 11167-11174 8 p.

Research output: Contribution to journalArticle

67 Scopus citations
2002

Cyclin D3 is essential for intestinal epithelial cell proliferation

Ko, T. C., Pan, F., Sheng, H., Brown, D. B., Thompson, E. A. & Beauchamp, R. D., Jul 1 2002, In : World Journal of Surgery. 26, 7, p. 812-818 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Protein kinase C βII and TGFβRII in ω-3 fatty acid-mediated inhibition of colon carcinogenesis

Murray, N. R., Weems, C., Chen, L., Leon, J., Wangsheng, W., Davidson, L. A., Jamieson, L., Chapkin, R. S., Aubrey Thompson, E. & Fields, A. P., Jun 10 2002, In : Journal of Cell Biology. 157, 6, p. 915-920 6 p.

Research output: Contribution to journalArticle

61 Scopus citations
2001

Cloning of a novel phosphatidylinositol kinase-related kinase. Characterization of the human SMG-1 RNA surveillance protein

Denning, G., Jamieson, L., Maquat, L. E., Thompson, E. A. & Fields, A. P., Jun 22 2001, In : Journal of Biological Chemistry. 276, 25, p. 22709-22714 6 p.

Research output: Contribution to journalArticle

119 Scopus citations
2000

A novel glucocorticoid receptor binding element within the murine c-myc promoter

Ma, T., Copland, J. A., Brasier, A. R. & Thompson, E. A., Jan 1 2000, In : Molecular Endocrinology. 14, 9, p. 1377-1386 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Comparison of GLUT1, GLUT3, and GLUT4 mRNA and the subcellular distribution of their proteins in normal human muscle

Stuart, C. A., Wen, G., Gustafson, W. C. & Thompson, E. A., Jan 1 2000, In : Metabolism: Clinical and Experimental. 49, 12, p. 1604-1609 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Glucocorticoid-mediated destabilization of cyclin D3 mRNA involves RNA-protein interactions in the 3'-untranslated region of the mRNA

Garcia-Gras, E. A., Chi, P. & Thompson, E. A., Jul 21 2000, In : Journal of Biological Chemistry. 275, 29, p. 22001-22008 8 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations
1998

TGF-β1 effects on proliferation of rat intestinal epithelial cells are due to inhibition of cyclin D1 expression

Ko, T. C., Yu, W., Sakai, T., Sheng, H., Shao, J., Beauchamp, R. D. & Thompson, E. A., Jul 2 1998, In : Oncogene. 16, 26, p. 3445-3454 10 p.

Research output: Contribution to journalArticle

Open Access
71 Scopus citations

The cyclin E promoter is activated by human cytomegalovirus 86-kDa immediate early protein

Bresnahan, W. A., Albrecht, T. & Thompson, E. A., Aug 21 1998, In : Journal of Biological Chemistry. 273, 34, p. 22075-22082 8 p.

Research output: Contribution to journalArticle

76 Scopus citations
1997

Cell cycle-mediated regulation of hepatic regeneration

Ehrenfried, J. A., Ko, T. C., Thompson, E. A. & Evers, B. M., Nov 1997, In : Surgery. 122, 5, p. 927-935 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Glucocorticoid inhibition of fibroblast proliferation and regulation of the cyclin kinase inhibitor p21(Cip1)

Ramalingam, A., Hirai, A. & Thompson, E. A., Jan 1 1997, In : Molecular Endocrinology. 11, 5, p. 577-586 10 p.

Research output: Contribution to journalArticle

Open Access
72 Scopus citations

Human cytomegalovirus infection results in altered Cdk2 subcellular localization

Bresnahan, W. A., Thompson, E. A. & Albrecht, T., Aug 1997, In : Journal of General Virology. 78, 8, p. 1993-1997 5 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Inhibition of cellular Cdk2 activity blocks human cytomegalovirus replication

Bresnahan, W. A., Boldogh, I., Chi, P., Thompson, E. A. & Albrecht, T., May 12 1997, In : Virology. 231, 2, p. 239-247 9 p.

Research output: Contribution to journalArticle

130 Scopus citations

N-(4-Hydroxyphenyl)retinamide induces apoptosis in T lymphoma and T Lymphoblastoid leukemia cells

Chan, L. N. L., Zhang, S., Shag, J., Waikela, R., Thompson, E. A. & Chan, T. S., Jan 1 1997, In : Leukemia and Lymphoma. 25, 42067, p. 271-280 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
1996

Cell cycle protein suppression and p21 induction in differentiating Caco-2 cells

Evers, B. M., Ko, T. C., Li, J. & Thompson, E. A., Oct 1 1996, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 271, 4 34-4, p. G722-G727

Research output: Contribution to journalArticle

65 Scopus citations

Cyclin E/Cdk2 activity is controlled by different mechanisms in the G0 and G1 phases of the cell cycle

Bresnahan, W. A., Boldogh, I., Ma, T., Albrecht, T. & Aubrey Thompson, E., Nov 7 1996, In : Cell Growth and Differentiation. 7, 10, p. 1283-1290 8 p.

Research output: Contribution to journalArticle

51 Scopus citations
4 Scopus citations

Human cytomegalovirus inhibits cellular DNA synthesis and arrests productively infected cells in late G1

Bresnahan, W. A., Boldogh, I., Thompson, E. A. & Albrecht, T., Oct 1 1996, In : Virology. 224, 1, p. 150-160 11 p.

Research output: Contribution to journalArticle

180 Scopus citations

Intestinal Cell Cycle Regulation: Interactions of Cyclin D1, Cdk4, and p21cip1

Beauchamp, R. D., Sheng, H. M., Shao, J. Y., Thompson, E. A. & Ko, T. C., Jan 1 1996, In : Annals of surgery. 223, 5, p. 620-628 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Regulation of thymidine kinase gene expression during liver regeneration and uterine tissue proliferation in transgenic mice

Lee, D. K., Sun, W., Rhee, K., Thompson, E. A., Lee, C. C. & Kim, K., Jan 1 1996, In : Transgenics. 2, 1, p. 89-98 10 p.

Research output: Contribution to journalArticle