• 5088 Citations
  • 37 Scopus h-Index
1981 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1981 2019

  • 5088 Citations
  • 37 Scopus h-Index
  • 147 Article
  • 2 Review article
  • 1 Comment/debate
Filter
Article
2019

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. M. & 1 others, Weinshilboum, R. M., Jan 1 2019, In : Clinical pharmacology and therapeutics.

Research output: Contribution to journalArticle

Open Access
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Pharmaceutical Preparations
Breast Neoplasms

A noninvasive blood-based combinatorial proteomic biomarker assay to detect breast cancer in women over age 50 with BI-RADS 3, 4, or 5 Assessment

Henderson, M. C., Silver, M., Tran, Q., Letsios, E. E., Mulpuri, R., Reese, D. E., Lourenco, A. P., LaBaer, J., Anderson, K. S., Alpers, J., Costantini, C., Rohatgi, N., Ali, H., Baker, K., Northfelt, D. W., Ghosh, K., Grobmyer, S. R., Polen, W. & Wolf, J. K., Jan 1 2019, In : Clinical Cancer Research. 25, 1, p. 142-149 8 p.

Research output: Contribution to journalArticle

Proteomics
Breast
Biomarkers
Breast Neoplasms
Biopsy

Are we choosing wisely in elderly females with breast cancer?

Calderon, E., Webb, C., Kosiorek, H. E., Richard J Gray, M. D., Cronin, P., Anderson, K., Northfelt, D. W., McCullough, A., Ocal, I. T. & Pockaj, B. A., Jan 1 2019, (Accepted/In press) In : American journal of surgery.

Research output: Contribution to journalArticle

Breast Neoplasms
Radiotherapy
Mammography
Sentinel Lymph Node Biopsy
Early Detection of Cancer
1 Citation (Scopus)
Technetium Tc 99m Sestamibi
Molecular Imaging
Breast
Breast Neoplasms
Drug Therapy

Depomedroxyprogesterone acetate therapy for hot flashes in survivors of breast cancer: no unfavorable impact on recurrence and survival

Ertz-Archambault, N. M., Rogoff, L. B., Kosiorek, H. E., Ernst, B., Anderson, K. S., Pockaj, B. A., Gray, R. J. & Northfelt, D. W., Jan 1 2019, (Accepted/In press) In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

Hot Flashes
Survivors
Acetates
Breast Neoplasms
Recurrence
2 Citations (Scopus)

Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer

McDonald, B. R., Contente-Cuomo, T., Sammut, S. J., Odenheimer-Bergman, A., Ernst, B., Perdigones, N., Chin, S. F., Farooq, M., Mejia, R., Cronin, P. A., Anderson, K. S., Kosiorek, H. E., Northfelt, D. W., McCullough, A. E., Patel, B., Weitzel, J. N., Slavin, T. P., Caldas, C., Pockaj, B. A. & Murtaza, M., Aug 7 2019, In : Science translational medicine. 11, 504, eaax7392.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Breast Neoplasms
DNA
Neoplasms
Alleles
2018
1 Citation (Scopus)

A phase 2 study of rituximab, cyclophosphamide, bortezomib and dexamethasone (R-CyBorD) in relapsed low grade and mantle cell lymphoma

Sonbol, M. B., Hilal, T., Dueck, A., Rosenthal, A. C., Conley, C. R., Kosiorek, H. E., Ginos, B. F., Gano, K. M., Nichols, C. S., Leis, J. F., Johnston, P. B., Habermann, T. M., Northfelt, D. W., Bergsagel, P. L., Inwards, D. J., Witzig, T. E., Ansell, S. M. & Reeder, C. B., Jan 11 2018, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-7 7 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Cyclophosphamide
Dexamethasone
Safety
Peripheral Nervous System Diseases
9 Citations (Scopus)

A phase i clinical trial of the Poly(ADP-ribose) polymerase inhibitor veliparib and weekly topotecan in patients with solid tumors

Wahner Hendrickson, A. E., Menefee, M. E., Hartmann, L. C., Long, H. J., Northfelt, D. W., Reid, J. M., Boakye-Agyeman, F., Kayode, O., Flatten, K. S., Harrell, M. I., Swisher, E. M., Poirer, G. G., Satele, D., Allred, J., Lensing, J. L., Chen, A., Ji, J., Zang, Y., Erlichman, C., Haluska, P. & 1 others, Kaufmann, S. H., Feb 15 2018, In : Clinical Cancer Research. 24, 4, p. 744-752 9 p.

Research output: Contribution to journalArticle

Topotecan
Clinical Trials
Neoplasms
Maximum Tolerated Dose
Mutation
21 Citations (Scopus)

Association of Circulating Tumor Cells with Late Recurrence of Estrogen Receptor-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial

Sparano, J., O'Neill, A., Alpaugh, K., Wolff, A. C., Northfelt, D. W., Dang, C. T., Sledge, G. W. & Miller, K. D., Jan 1 2018, (Accepted/In press) In : JAMA oncology.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Estrogen Receptors
Randomized Controlled Trials
Breast Neoplasms
Recurrence
1 Citation (Scopus)

Breast MRI phenotype and background parenchymal enhancement may predict tumor response to neoadjuvant endocrine therapy

Hilal, T., Covington, M., Kosiorek, H. E., Zwart, C., Ocal, I. T., Pockaj, B. A., Northfelt, D. W. & Patel, B., Jan 1 2018, (Accepted/In press) In : Breast Journal.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Breast
Phenotype
Neoplasms
Breast Neoplasms
4 Citations (Scopus)

Choosing wisely after publication of level I evidence in breast cancer radiotherapy

Niska, J. R., Keole, S. R., Pockaj, B. A., Halyard, M. Y., Patel, S. H., Northfelt, D. W., Gray, R. J., Wasif, N., Vargas, C. E. & Wong, W. W., Feb 9 2018, In : Breast Cancer: Targets and Therapy. 10, p. 31-37 7 p.

Research output: Contribution to journalArticle

Publications
Radiotherapy
Breast Neoplasms
Breast
Appointments and Schedules
13 Citations (Scopus)

Contrast-Enhanced Spectral Mammography is Comparable to MRI in the Assessment of Residual Breast Cancer Following Neoadjuvant Systemic Therapy

Patel, B., Hilal, T., Covington, M., Zhang, N., Kosiorek, H. E., Lobbes, M., Northfelt, D. W. & Pockaj, B. A., Mar 7 2018, (Accepted/In press) In : Annals of Surgical Oncology. p. 1-7 7 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Residual Neoplasm
Mammography
Breast Neoplasms
Neoplasms
13 Citations (Scopus)

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

Yu, J., Qin, B., Moyer, A., Nowsheen, S., Liu, T., Qin, S., Zhuang, Y., Liu, D., Lu, S. W., Kalari, K. R., Visscher, D. W., Copland, J. A. III., McLaughlin, S. A., Moreno Aspitia, A., Northfelt, D. W., Gray, R. J., Lou, Z., Suman, V. J., Weinshilboum, R. M., Boughey, J. C. & 2 others, Goetz, M. P. & Wang, L. M., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2376-2388 13 p.

Research output: Contribution to journalArticle

decitabine
Triple Negative Breast Neoplasms
Methyltransferases
DNA
Biomarkers
5 Citations (Scopus)

Double-blind phase III trial of adjuvant chemotherapy withand without bevacizumab in patients with lymph node-positiveand high-risk lymph node-negative breast cancer (E5103)

Miller, K. D., O'Neill, A., Gradishar, W., Hobday, T. J., Goldstein, L. J., Mayer, I. A., Bloom, S., Brufsky, A. M., Tevaarwerk, A. J., Sparano, J. A., Le-Lindqwister, N. A., Hendricks, C. B., Northfelt, D. W., Dang, C. T. & Sledge, G. W., Sep 1 2018, In : Journal of Clinical Oncology. 36, 25, p. 2621-2629 9 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Lymph Nodes
Breast Neoplasms
Cyclophosphamide
Disease-Free Survival
1 Citation (Scopus)

Generation of HER2-specific antibody immunity during trastuzumab adjuvant therapy associates with reduced relapse in resected HER2 breast cancer

Norton, N., Fox, N., McCarl, C. A., Tenner, K. S., Ballman, K., Erskine, C. L., Necela, B. M., Northfelt, D. W., Tan, W., Calfa, C., Pegram, M., Colon-Otero, G., Perez, E. A., Clynes, R. & Knutson, K. L., Jun 14 2018, In : Breast Cancer Research. 20, 1, 52.

Research output: Contribution to journalArticle

Immunity
Breast Neoplasms
Recurrence
Antibodies
Disease-Free Survival
1 Citation (Scopus)

N0332 phase 2 trial of weekly irinotecan hydrochloride and docetaxel in refractory metastatic breast cancer: a North Central Cancer Treatment Group (NCCTG) Trial

Tan, W. W., Hillman, D. W., Salim, M., Northfelt, D. W., Anderson, D. M., Stella, P. J., Niedringhaus, R., Bernath, A. M., Gamini, S. S., Palmieri, F. & Perez, E. A., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, 10, 1 p.

Research output: Contribution to journalArticle

irinotecan
docetaxel
Manuscripts
Organized Financing
Breast Neoplasms
2017
22 Citations (Scopus)

A phase II trial of neoadjuvant MK-2206, an AKT inhibitor, with anastrozole in clinical stage II or III PIK3CA-mutant ER-positive and HER2-negative breast cancer

Ma, C. X., Suman, V. J., Goetz, M. P., Northfelt, D. W., Burkard, M. E., Ademuyiwa, F., Naughton, M., Margenthaler, J., Aft, R., Gray, R., Tevaarwerk, A., Wilke, L., Haddad, T. C., Moynihan, T., Loprinzi, C. L., Hieken, T. J., Barnell, E. K., Skidmore, Z. L., Feng, Y. Y., Krysiak, K. & 14 others, Hoog, J., Guo, Z., Nehring, L., Wisinski, K. B., Mardis, E., Hagemann, I. S., Vij, K., Sanati, S., Al-Kateb, H., Griffith, O. L., Griffith, M., Doyle, L., Erlichman, C. & Ellis, M. J., Nov 15 2017, In : Clinical Cancer Research. 23, 22, p. 6823-6832 10 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Estrogens
Phosphorylation
Goserelin
Apoptosis
1 Citation (Scopus)

Does biomarker information impact breast cancer patients’ preferences and physician recommendation for adjuvant chemotherapy?

Partridge, A. H., Sepucha, K., O’Neill, A., Miller, K. D., Baker, E., Dang, C. T., Northfelt, D. W., Sledge, G. W. & Schneider, B. P., Jun 23 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-9 9 p.

Research output: Contribution to journalArticle

Patient Preference
Adjuvant Chemotherapy
Biomarkers
Breast Neoplasms
Physicians
9 Citations (Scopus)

Efficacy of the oral mTORC1 inhibitor everolimus in relapsed or refractory indolent lymphoma

Bennani, N., LaPlant, B. R., Ansell, S. M., Habermann, T. M., Inwards, D. J., Micallef, I., Johnston, P. B., Porrata, L. F., Colgan, J. P., Markovic, S. N., Nowakowski, G. S., Macon, W. R., Reeder, C. B., Mikhael, J. R., Northfelt, D. W., Ghobrial, I. M. & Witzig, T. E., May 1 2017, In : American Journal of Hematology. 92, 5, p. 448-453 6 p.

Research output: Contribution to journalArticle

Lymphoma
Therapeutics
Safety
Febrile Neutropenia
Everolimus
9 Citations (Scopus)

Enrichment of PI3K-AKT–mTOR pathway activation in hepatic metastases from breast cancer

Pierobon, M., Ramos, C., Wong, S., Hodge, K. A., Aldrich, J., Byron, S., Anthony, S. P., Robert, N. J., Northfelt, D. W., Jahanzeb, M., Vocila, L., Wulfkuhle, J., Gambara, G., Gallagher, R. I., Dunetz, B., Hoke, N., Dong, T., Craig, D. W., Cristofanilli, M., Leyland-Jones, B. & 4 others, Liotta, L. A., O'Shaughnessy, J. A., Carpten, J. D. & Petricoin, E. F., Aug 15 2017, In : Clinical Cancer Research. 23, 16, p. 4919-4928 10 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
Breast Neoplasms
Neoplasm Metastasis
Liver
Protein Array Analysis
11 Citations (Scopus)

Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study

Yu, J., Qin, B., Moyer, A., Sinnwell, J. P., Thompson, K. J., Copland, J. A. III., Marlow, L. A., Miller, J. L., Yin, P., Gao, B., Minter-Dykhouse, K., Tang, X., McLaughlin, S. A., Moreno Aspitia, A., Schweitzer, A., Lu, Y., Hubbard, J., Northfelt, D. W., Gray, R. J., Hunt, K. & 10 others, Conners, A. L., Suman, V. J., Kalari, K. R., Ingle, J. N., Lou, Z., Visscher, D. W., Weinshilboum, R. M., Boughey, J. C., Goetz, M. P. & Wang, L. M., Dec 6 2017, In : Breast cancer research : BCR. 19, 1, 1 p.

Research output: Contribution to journalArticle

Heterografts
Breast Neoplasms
Biopsy
Drug Therapy
Neoplasms
22 Citations (Scopus)

First-in-human phase I Study of the tamoxifen metabolite Z-endoxifen in women with endocrine-refractory metastatic breast cancer

Goetz, M. P., Suman, V. J., Reid, J. M., Northfelt, D. W., Mahr, M. A., Ralya, A. T., Kuffel, M., Visscher, S. A., Kipp, B. R., Liu, M. C., Hawse, J. R., Ames, M. M., Ingle Buhrow, J. N., Safgren, S. L., McGovern, R. M., Black, J., Dockter, T., Haddad, T. C., Erlichman, C., Adjei, A. & 7 others, Collins, D., Streicher, H., Chalmers, Z. R., Frampton, G., Hawse, J. R., Doroshow, J. H. & Collins, J. M., Oct 20 2017, In : Journal of Clinical Oncology. 35, 30, p. 3391-3400 10 p.

Research output: Contribution to journalArticle

Tamoxifen
Breast Neoplasms
Maximum Tolerated Dose
Mutation
Cytochrome P-450 CYP2D6
68 Citations (Scopus)

NeoPalAna: Neoadjuvant palbociclib, a cyclin-dependent kinase 4/6 inhibitor, and anastrozole for clinical stage 2 or 3 estrogen receptor–positive breast cancer

Ma, C. X., Gao, F., Luo, J., Northfelt, D. W., Goetz, M. P., Forero, A., Hoog, J., Naughton, M., Ademuyiwa, F., Suresh, R., Anderson, K. S., Margenthaler, J., Aft, R., Hobday, T. J., Moynihan, T., Gillanders, W., Cyr, A., Eberlein, T. J., Hieken, T. J., Krontiras, H. & 14 others, Guo, Z., Lee, M. V., Spies, N. C., Skidmore, Z. L., Griffith, O. L., Griffith, M., Thomas, S., Bumb, C., Vij, K., Huang Bartlett, C., Koehler, M., Al-Kateb, H., Sanati, S. & Ellis, M. J., Aug 1 2017, In : Clinical Cancer Research. 23, 15, p. 4055-4065 11 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinase 4
Estrogens
Breast Neoplasms
Cell Cycle Checkpoints
40 Citations (Scopus)

Safety and activity of varlilumab, a novel and first-in-class agonist anti-CD27 antibody, in patients with advanced solid tumors

Burris, H. A., Infante, J. R., Ansell, S. M., Nemunaitis, J. J., Weiss, G. R., Villalobos, V. M., Sikic, B. I., Taylor, M. H., Northfelt, D. W., Carson, W. E., Hawthorne, T. R., Davis, T. A., Yellin, M. J., Keler, T. & Bullock, T., Jun 20 2017, In : Journal of Clinical Oncology. 35, 18, p. 2028-2036 9 p.

Research output: Contribution to journalArticle

Anti-Idiotypic Antibodies
Safety
Neoplasms
T-Lymphocytes
Disease-Free Survival
15 Citations (Scopus)

Serum thymidine kinase 1 activity as a pharmacodynamic marker of cyclin-dependent kinase 4/6 inhibition in patients with early-stage breast cancer receiving neoadjuvant palbociclib

Bagegni, N., Thomas, S., Liu, N., Luo, J., Hoog, J., Northfelt, D. W., Goetz, M. P., Forero, A., Bergqvist, M., Karen, J., Neumüller, M., Suh, E. M., Guo, Z., Vij, K., Sanati, S., Ellis, M. & Ma, C. X., Nov 21 2017, In : Breast Cancer Research. 19, 1, 123.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinase 4
Breast Neoplasms
Serum
Neoplasms
7 Citations (Scopus)

SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway

Dudenkov, T. M., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Ibrahim-zada, I., Batzler, A., Jenkins, G. D., Pietrzak, T. L., Carlson, E. E., Barman, P., Goetz, M. P., Northfelt, D. W., Moreno-Aspita, A., Williard, C. V., Kalari, K. R., Nakamura, Y., Wang, L. M. & Weinshilboum, R. M., Jul 1 2017, In : Breast Cancer Research and Treatment. 164, 1, p. 189-199 11 p.

Research output: Contribution to journalArticle

Estrone
Genome-Wide Association Study
Androstenedione
Single Nucleotide Polymorphism
Steryl-Sulfatase
9 Citations (Scopus)

Survival benefit needed to undergo chemotherapy: Patient and physician preferences

Vaz-Luis, I., O'Neill, A., Sepucha, K., Miller, K. D., Baker, E., Dang, C. T., Northfelt, D. W., Winer, E. P., Sledge, G. W., Schneider, B. & Partridge, A. H., Aug 1 2017, In : Cancer. 123, 15, p. 2821-2828 8 p.

Research output: Contribution to journalArticle

Patient Preference
Physicians
Drug Therapy
Survival
Adjuvant Chemotherapy
2 Citations (Scopus)

The success of sentinel lymph node biopsy after neoadjuvant therapy: A single institution review

Chang, J. M., Kosiorek, H. E., Wasif, N., Gray, R. J., Stucky, C. C. H., Northfelt, D. W., Anderson, K. S., McCullough, A. E., Ocal, I. T. & Pockaj, B. A., 2017, (Accepted/In press) In : American Journal of Surgery.

Research output: Contribution to journalArticle

Sentinel Lymph Node Biopsy
Neoadjuvant Therapy
Lymph Node Excision
Breast Neoplasms
Triple Negative Breast Neoplasms
15 Citations (Scopus)

Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

Goetz, M. P., Kalari, K. R., Suman, V. J., Moyer, A. M., Yu, J., Visscher, D. W., Dockter, T. J., Vedell, P. T., Sinnwell, J. P., Tang, X., Thompson, K. J., McLaughlin, S. A., Moreno-Aspitia, A., Copland, J. A., Northfelt, D. W., Gray, R. J., Hunt, K., Conners, A., Weinshilboum, R., Wang, L. & 1 others, Boughey, J. C., Jul 1 2017, In : Journal of the National Cancer Institute. 109, 7, djw306.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Heterografts
Breast Neoplasms
Drug Therapy
Neoplasms
2016
124 Citations (Scopus)

Adaptive randomization of neratinib in early breast cancer

the I-SPY 2 Investigators, Jul 7 2016, In : New England Journal of Medicine. 375, 1, p. 11-22 12 p.

Research output: Contribution to journalArticle

Random Allocation
Breast Neoplasms
Biomarkers
Hormones
Neoadjuvant Therapy
196 Citations (Scopus)

Adaptive randomization of veliparib-carboplatin treatment in breast cancer

the I-SPY 2 Investigators, Jul 7 2016, In : New England Journal of Medicine. 375, 1, p. 23-34 12 p.

Research output: Contribution to journalArticle

Carboplatin
Random Allocation
Breast Neoplasms
Biomarkers
Triple Negative Breast Neoplasms
2 Citations (Scopus)

A Study of Combination Bicalutamide and Raloxifene for Patients With Castration-Resistant Prostate Cancer

Ho, T. H., Nunez-Nateras, R., Hou, Y. X., Bryce, A. H., Northfelt, D. W., Dueck, A., Wong, B., Stanton, M. L., Joseph, R. W. & Castle, E. P., Jul 8 2016, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Estrogen Receptors
Quality of Life
Therapeutics
24 Citations (Scopus)

Clinical and Translational Results of a Phase II, Randomized Trial of an AntiIGF-1R (Cixutumumab) in Women with Breast Cancer That Progressed on Endocrine Therapy

Gradishar, W. J., Yardley, D. A., Layman, R., Sparano, J. A., Chuang, E., Northfelt, D. W., Schwartz, G. N., Youssoufian, H., Tang, S., Novosiadly, R., Forest, A., Nguyen, T. S., Cosaert, J., Grebennik, D. & Haluska, P., Jan 15 2016, In : Clinical Cancer Research. 22, 2, p. 301-309 9 p.

Research output: Contribution to journalArticle

Insulin Receptor
Breast Neoplasms
Therapeutics
Disease-Free Survival
Estrogen Receptor Modulators
24 Citations (Scopus)

Improved survival of HER2+ breast cancer patients treated with trastuzumab and chemotherapy is associated with host antibody immunity against the HER2 intracellular domain

Knutson, K. L., Clynes, R., Shreeder, B., Yeramian, P., Kemp, K. P., Ballman, K., Tenner, K. S., Erskine, C. L., Norton, N., Northfelt, D. W., Tan, W., Calfa, C., Pegram, M., Mittendorf, E. A. & Perez, E. A., Jul 1 2016, In : Cancer Research. 76, 13, p. 3702-3710 9 p.

Research output: Contribution to journalArticle

Immunity
Breast Neoplasms
Drug Therapy
Survival
Antibodies

Living with Cancer: an Educational Intervention in Cancer Patients Can Improve Patient-Reported Knowledge Deficit

Padrnos, L., Bennett, R., Kosiorek, H., Dueck, A., Northfelt, D. W., Mikhael, J. R., Tibes, R., Khera, N. D. & Mesa, R. A., Oct 11 2016, (Accepted/In press) In : Journal of Cancer Education. p. 1-7 7 p.

Research output: Contribution to journalArticle

Neoplasms
Delivery of Health Care
Quality of Life
Demography
Hematologic Diseases
16 Citations (Scopus)

Phase i Study of Panobinostat (LBH589) and Letrozole in Postmenopausal Metastatic Breast Cancer Patients

Tan, W., Allred, J. B., Moreno Aspitia, A., Northfelt, D. W., Ingle, J. N., Goetz, M. P. & Perez, E. A., Apr 1 2016, In : Clinical Breast Cancer. 16, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

letrozole
Breast Neoplasms
Histone Deacetylase Inhibitors
Triple Negative Breast Neoplasms
Maximum Tolerated Dose
5 Citations (Scopus)

Temporal Trends of Cardiac Chambers Function with Trastuzumab in Human Epidermal Growth Factor Receptor II-Positive Breast Cancer Patients

Moustafa, S., Murphy, K., Nelluri, B. K., Northfelt, D. W., Shah, P., Lee, H., Wilansky, S., Naqvi, T. Z., Meyer, S. & Mookadam, F., Mar 1 2016, In : Echocardiography. 33, 3, p. 406-415 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Breast Neoplasms
Right Atrial Function
Right Ventricular Function
Trastuzumab
2015
9 Citations (Scopus)

Back to Basics: Traditional Nottingham Grade Mitotic Counts Alone are Significant in Predicting Survival in Invasive Breast Carcinoma

Chang, J. M., McCullough, A. E., Dueck, A., Kosiorek, H. E., Ocal, I. T., Lidner, T. K., Gray, R. J., Wasif, N., Northfelt, D. W., Anderson, K. S. & Pockaj, B. A., May 22 2015, (Accepted/In press) In : Annals of Surgical Oncology.

Research output: Contribution to journalArticle

Breast Neoplasms
Survival
Mitosis
Recurrence
Estrogen Receptors
3 Citations (Scopus)

Effect of unblinding on participants' perceptions of risk and confidence in a large double-blind clinical trial of chemotherapy for breast cancer

Partridge, A. H., Sepucha, K., O'Neill, A., Miller, K. D., Motley, C., Swaby, R. F., Schneider, B. P., Dang, C. T., Northfelt, D. W. & Sledge, G. W., Jun 1 2015, In : JAMA oncology. 1, 3, p. 369-374 6 p.

Research output: Contribution to journalArticle

Placebos
Clinical Trials
Breast Neoplasms
Drug Therapy
Investigational Therapies
7 Citations (Scopus)

Evaluation of CYP2D6 enzyme activity using a 13C-dextromethorphan breath test in women receiving adjuvant tamoxifen

Safgren, S. L., Suman, V. J., Kosel, M. L., Gilbert, J. A., Buhrow, S. A., Black, J. L., Northfelt, D. W., Modak, A. S., Rosen, D., Ingle, J. N., Ames, M. M., Reid, J. M. & Goetz, M. P., Mar 27 2015, In : Pharmacogenetics and Genomics. 25, 4, p. 157-163 7 p.

Research output: Contribution to journalArticle

Dextromethorphan
Cytochrome P-450 CYP2D6
Breath Tests
Tamoxifen
Enzymes
11 Citations (Scopus)

Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapy

Ellingson, M. S., Hart, S., Kalari, K. R., Suman, V. J., Schahl, K. A., Dockter, T. J., Felten, S. J., Sinnwell, J. P., Thompson, K. J., Tang, X., Vedell, P. T., Barman, P., Sicotte, H., Eckel-Passow, J. E., Northfelt, D. W., Gray, R. J., McLaughlin, S. A., Moreno Aspitia, A., Ingle, J. N., Moyer, A. & 9 others, Visscher, D. W., Jones, K., Conners, A., McDonough, M., Wieben, E. D., Wang, L. M., Weinshilboum, R. M., Boughey, J. C. & Goetz, M. P., Sep 7 2015, In : Breast Cancer Research and Treatment. 153, 2, p. 435-443 9 p.

Research output: Contribution to journalArticle

Exome
Neoplasm Genes
Breast Neoplasms
Drug Therapy
Genes
2 Citations (Scopus)

Factitious disorder in Crohn's disease: Recurrent pancytopenia caused by surreptitious ingestion of 6-mercaptopurine

Kahn, A., Boroff, E. S., Martin, K. A., Northfelt, D. W. & Heigh, R. I., May 1 2015, In : Case Reports in Gastroenterology. 9, p. 137-141 5 p.

Research output: Contribution to journalArticle

Factitious Disorders
6-Mercaptopurine
Pancytopenia
Crohn Disease
Eating
58 Citations (Scopus)

Genomic amplification of 9p24.1 targeting JAK2, PD-L1, and PD-L2 is enriched in high-risk triple negative breast cancer

Barrett, M., Anderson, K. S., Lenkiewicz, E., Andreozzi, M., Cunliffe, H. E., Klassen, C. L., Dueck, A., McCullough, A. E., Reddy, S. K., Ramanathan, R. K., Northfelt, D. W. & Pockaj, B. A., 2015, In : Oncotarget. 6, 28, p. 26483-26493 11 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Comparative Genomic Hybridization
Glioblastoma
Oligonucleotide Array Sequence Analysis
Disease-Free Survival
4 Citations (Scopus)

Impact of race and ethnicity on outcomes and health care utilization after allogeneic hematopoietic cell transplantation

Khera, N. D., Chang, Y. H., Slack, J. L., Fauble, V., Leis, J. F., Noel, P., Sproat, L., Palmer, J., Adams, R., Fitch, T., Northfelt, D. W., Guy, M., Tilburt, J. C. & Mikhael, J. R., Apr 1 2015, In : Leukemia and Lymphoma. 56, 4, p. 987-992 6 p.

Research output: Contribution to journalArticle

Patient Acceptance of Health Care
Cell Transplantation
Transplants
Medicare
Insurance
14 Citations (Scopus)

Late-stage cancer patients remain highly responsive to immune activation by the selective TLR8 agonist motolimod (VTX-2337)

Dietsch, G. N., Randall, T. D., Gottardo, R., Northfelt, D. W., Ramanathan, R. K., Cohen, P. A., Manjarrez, K. L., Newkirk, M., Bryan, J. K. & Hershberg, R. M., Dec 15 2015, In : Clinical Cancer Research. 21, 24, p. 5445-5452 8 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 8
Neoplasms
Healthy Volunteers
Pharmacokinetics
Biomarkers
4 Citations (Scopus)

Quality of life and disease understanding: Impact of attending a patient-centered cancer symposium

Padrnos, L., Dueck, A., Scherber, R., Glassley, P., Stigge, R., Northfelt, D. W., Mikhael, J. R., Aguirre, A., Bennett, R. M. & Mesa, R. A., Jun 1 2015, In : Cancer Medicine. 4, 6, p. 800-807 8 p.

Research output: Contribution to journalArticle

Quality of Life
Fatigue
Neoplasms
Knowledge Management
Knowledge Bases
4 Citations (Scopus)

Regional recurrence in the era of sentinel lymph node biopsy

Linnaus, M. E., Dueck, A., Kosiorek, H. E., Gray, R. J., Wasif, N., Northfelt, D. W., Anderson, K. S., McCullough, A. E., Wong, W. W., Halyard, M. Y., Patel, S. H. & Pockaj, B. A., Dec 1 2015, In : American Journal of Surgery. 210, 6, p. 1155-1161 7 p.

Research output: Contribution to journalArticle

Sentinel Lymph Node Biopsy
Recurrence
Databases
Breast Neoplasms
Incidence
2014
19 Citations (Scopus)

A Phase I/II Study of Bortezomib in Combination with Paclitaxel, Carboplatin and Concurrent Thoracic Radiation Therapy for Non-Small Cell Lung Cancer: NCCTG-N0321

Zhao, Y., Foster, N. R., Meyers, J. P., Thomas, S. P., Northfelt, D. W., Rowland, K. M., Mattar, B. I., Johnson, D. B., Molina, J. R., Mandrekar, S. J., Schild, S. E., Bearden, J. D., Aubry, M. C. & Adjei, A., Sep 22 2014, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Carboplatin
Paclitaxel
Non-Small Cell Lung Carcinoma
Radiotherapy
Thorax
26 Citations (Scopus)

A phase I dose-finding study of the novel toll-like receptor 8 agonist VTX-2337 in adult subjects with advanced solid tumors or lymphoma

Northfelt, D. W., Ramanathan, R. K., Cohen, P. A., Von Hoff, D. D., Weiss, G. J., Dietsch, G. N., Manjarrez, K. L., Randall, T. D. & Hershberg, R. M., Jul 15 2014, In : Clinical Cancer Research. 20, 14, p. 3683-3691 9 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 8
Lymphoma
Maximum Tolerated Dose
Pharmacokinetics
Neoplasms
23 Citations (Scopus)

Biomarker prediction of chemotherapy-related amenorrhea in premenopausal women with breast cancer participating in E5103

Ruddy, K. J., O'Neill, A., Miller, K. D., Schneider, B. P., Baker, E., Sparano, J. A., Dang, C., Northfelt, D. W., Sledge, G. W. & Partridge, A. H., 2014, In : Breast Cancer Research and Treatment. 144, 3, p. 591-597 7 p.

Research output: Contribution to journalArticle

Amenorrhea
Anti-Mullerian Hormone
Biomarkers
Breast Neoplasms
Drug Therapy