• 1379 Citations
  • 19 Scopus h-Index
20062019
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Research Output 2006 2019

  • 1379 Citations
  • 19 Scopus h-Index
  • 55 Article
  • 2 Chapter
  • 1 Conference contribution
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Article
2019
2 Citations (Scopus)

Comparative Effectiveness of Behavioral Interventions on Quality of Life for Older Adults With Mild Cognitive Impairment: A Randomized Clinical Trial

Chandler, M. J., Locke, D. E., Crook, J., Fields, J. A., Ball, C. T., Phatak, V. S., Dean, P. M., Morris, M. & Smith, G. E., May 3 2019, In : JAMA network open. 2, 5, p. e193016

Research output: Contribution to journalArticle

Open Access
Randomized Controlled Trials
Quality of Life
Yoga
Self-Help Groups
Activities of Daily Living

Functional ability is associated with higher adherence to behavioral interventions in mild cognitive impairment

Sr, P. A. A., DeFeis, B., De Wit, L., O’Shea, D., Mejia, A., Chandler, M., Locke, D. E. C., Fields, J., Phatak, V., Dean, P. M., Crook, J. & Smith, G., Jan 1 2019, (Accepted/In press) In : Clinical Neuropsychologist.

Research output: Contribution to journalArticle

Open Access
Aptitude
Depression
Yoga
Education
Training Support
Apolipoproteins
Cognition
Quality of Life
Exercise
Short-Term Memory
1 Citation (Scopus)

Memory Support System training in mild cognitive impairment: Predictors of learning and adherence

De Wit, L., Chandler, M., Amofa, P., DeFeis, B., Mejia, A., O’Shea, D., Locke, D. E. C., Fields, J. A. & Smith, G. E., Jan 1 2019, (Accepted/In press) In : Neuropsychological Rehabilitation.

Research output: Contribution to journalArticle

Training Support
Learning
Cognition
Aptitude
Self Efficacy

Self-efficacy mediates the association between physical function and perceived quality of life in individuals with mild cognitive impairment

Langer, K., O'Shea, D. M., De Wit, L., Defeis, B., Mejia, A., Amofa, P., Chandler, M. J., Locke, D. E., Fields, J. A., Phatak, V., Dean, P. M. & Smith, G., Jan 1 2019, In : Journal of Alzheimer's Disease. 68, 4, p. 1511-1519 9 p.

Research output: Contribution to journalArticle

Self Efficacy
Quality of Life
Cognitive Dysfunction
Value of Life
Education
2018
4 Citations (Scopus)

A Survey of Patient and Partner Outcome and Treatment Preferences in Mild Cognitive Impairment

Smith, G. E., Chandler, M. J., Fields, J. A., Aakre, J. & Locke, D. E., Jan 1 2018, In : Journal of Alzheimer's Disease. 63, 4, p. 1459-1468 10 p.

Research output: Contribution to journalArticle

Patient Preference
Caregivers
Self Efficacy
Surveys and Questionnaires
Cognitive Dysfunction

Diagnostic utility of the Minnesota Multiphasic Personality Inventory-2 Restructured Form in the epilepsy monitoring unit: Considering sex differences

Duncan, C. J., Roberts, N. A., Kirlin, K. A., Parkhurst, D., Burleson, M. H., Drazkowski, J. F., Sirven, J. I., Noe, K. H., Crepeau, A. Z., Hoerth, M. T. & Locke, D. E., Nov 1 2018, In : Epilepsy and Behavior. 88, p. 117-122 6 p.

Research output: Contribution to journalArticle

MMPI
Sex Characteristics
Epilepsy
Seizures
Differential Diagnosis
1 Citation (Scopus)

Neuropsychological comparison of incident MCI and prevalent MCI

Hansen, A., Caselli, R. J., Schlosser-Covell, G., Golafshar, M. A., Dueck, A., Woodruff, B. K., Stonnington, C. M., Geda, Y. E. & Locke, D. E., Jan 1 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 599-603 5 p.

Research output: Contribution to journalArticle

Cognitive Dysfunction
Research Subjects
Memory Disorders
Alzheimer Disease
Research
12 Citations (Scopus)

Personality Changes During the Transition from Cognitive Health to Mild Cognitive Impairment

Caselli, R. J., Langlais, B. T., Dueck, A., Henslin, B. R., Johnson, T. A., Woodruff, B. K., Hoffman-Snyder, C. & Locke, D. E., Apr 1 2018, In : Journal of the American Geriatrics Society. 66, 4, p. 671-678 8 p.

Research output: Contribution to journalArticle

Health Transition
Personality
Confidence Intervals
Alzheimer Disease
Personality Tests
3 Citations (Scopus)

Predicting Imminent Progression to Clinically Significant Memory Decline Using Volumetric MRI and FDG PET

Stonnington, C. M., Chen, Y., Savage, C. R., Lee, W., Bauer, R. J., Sharieff, S., Thiyyagura, P., Alexander, G. E., Caselli, R. J., Locke, D. E., Reiman, E. M. & Chen, K., Jan 1 2018, In : Journal of Alzheimer's Disease. 63, 2, p. 603-615 13 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Magnetic Resonance Imaging
Positron-Emission Tomography
Aptitude
Alleles
Health Transition
Personality
Cognitive Dysfunction
1 Citation (Scopus)

Subjective cognitive impairment and the broad autism phenotype

Caselli, R. J., Langlais, B. T., Dueck, A., Locke, D. E. & Woodruff, B. K., Jan 1 2018, In : Alzheimer Disease and Associated Disorders. 32, 4, p. 284-290 7 p.

Research output: Contribution to journalArticle

Autistic Disorder
Phenotype
Symptom Assessment
Cognitive Dysfunction
Personality
2017
1 Citation (Scopus)

A pilot randomized trial of two cognitive rehabilitation interventions for mild cognitive impairment: Caregiver outcomes

Cuc, A. V., Locke, D. E., Duncan, N., Fields, J. A., Snyder, C. H., Hanna, S., Lunde, A., Smith, G. E. & Chandler, M. J., 2017, (Accepted/In press) In : International Journal of Geriatric Psychiatry.

Research output: Contribution to journalArticle

Caregivers
Rehabilitation
Anxiety
Quality of Life
Depression
4 Citations (Scopus)

Computer versus compensatory calendar training in individuals with mild cognitive impairment: Functional impact in a pilot study

Chandler, M. J., Locke, D. E., Duncan, N. L., Hanna, S. M., Cuc, A. V., Fields, J. A., Hoffman Snyder, C. R., Lunde, A. M. & Smith, G. E., Sep 6 2017, In : Brain Sciences. 7, 9, 112.

Research output: Contribution to journalArticle

Activities of Daily Living
Self Efficacy
Rehabilitation
Control Groups
Calendars

Lorazepam Challenge for Individuals at Varying Genetic Risk for Alzheimer Disease

Stonnington, C. M., Harel, B., Locke, D. E., Hentz, J. G., Zhang, N., Maruff, P. & Caselli, R. J., Jun 2 2017, (Accepted/In press) In : Alzheimer Disease and Associated Disorders.

Research output: Contribution to journalArticle

Lorazepam
Alzheimer Disease
Short-Term Memory
Poly T
Executive Function
2016
17 Citations (Scopus)

Impact of Personality on Cognitive Aging: A Prospective Cohort Study

Caselli, R. J., Dueck, A., Locke, D. E., Henslin, B. R., Johnson, T. A., Woodruff, B. K., Hoffman-Snyder, C. & Geda, Y. E., Aug 1 2016, In : Journal of the International Neuropsychological Society. 22, 7, p. 765-776 12 p.

Research output: Contribution to journalArticle

Personality
neuroticism
personality
Cohort Studies
Apolipoprotein E4
6 Citations (Scopus)

Patients with psychogenic nonepileptic seizures report more severe migraine than patients with epilepsy

Shepard, M. A., Silva, A., Starling, A., Hoerth, M. T., Locke, D. E., Ziemba, K., Chong, C. D. & Schwedt, T. J., Jan 1 2016, In : Seizure. 34, p. 78-82 5 p.

Research output: Contribution to journalArticle

Migraine Disorders
Epilepsy
Seizures
Headache
Chi-Square Distribution
11 Citations (Scopus)

Priority of Treatment Outcomes for Caregivers and Patients with Mild Cognitive Impairment: Preliminary Analyses

Barrios, P. G., González, R. P., Hanna, S. M., Lunde, A. M., Fields, J. A., Locke, D. E. & Smith, G. E., Dec 1 2016, In : Neurology and Therapy. 5, 2, p. 183-192 10 p.

Research output: Contribution to journalArticle

Caregivers
Cognitive Dysfunction
Proxy
Self Efficacy
Neurodegenerative Diseases
2015
2 Citations (Scopus)

Analysis of minnesota multiphasic personality inventory-2-Restructured form response bias indicators as suppressors or moderators in a medical setting

Wershba, R. E., Locke, D. E. & Lanyon, R. I., Jun 1 2015, In : Psychological Assessment. 27, 2, p. 733-737 5 p.

Research output: Contribution to journalArticle

MMPI
Epilepsy
Aptitude
Logistic Models
Psychology
5 Citations (Scopus)

Apoe ε4 genotype and the risk for subjective cognitive impairment in elderly persons

Krell-Roesch, J., Woodruff, B. K., Acosta, J. I., Locke, D. E., Hentz, J. G., Stonnington, C. M., Stokin, G. B., Nagle, C., Michel, B. F., Sambuchi, N., Caselli, R. J. & Geda, Y. E., Sep 1 2015, In : Journal of Neuropsychiatry and Clinical Neurosciences. 27, 4, p. 322-325 4 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Apolipoproteins E
Genotype
Sex Education
Marital Status
12 Citations (Scopus)

Quality of life in psychogenic nonepileptic seizures and epilepsy: The role of somatization and alexithymia

Wolf, L. D., Hentz, J. G., Ziemba, K. S., Kirlin, K. A., Noe, K. H., Hoerth, M. T., Crepeau, A. Z., Sirven, J. I., Drazkowski, J. F. & Locke, D. E., Feb 1 2015, In : Epilepsy and Behavior. 43, p. 81-88 8 p.

Research output: Contribution to journalArticle

Affective Symptoms
Epilepsy
Seizures
Quality of Life
Physiologic Monitoring
24 Citations (Scopus)

Role of theory of mind in emotional awareness and alexithymia: Implications for conceptualization and measurement

Lane, R. D., Hsu, C. H., Locke, D. E., Ritenbaugh, C. & Stonnington, C. M., 2015, In : Consciousness and Cognition. 33, p. 398-405 8 p.

Research output: Contribution to journalArticle

Theory of Mind
Affective Symptoms
Emotions
Anomia
Agnosia
12 Citations (Scopus)
Cognitive Reserve
Verbal Learning
Proxy
Cognitive Aging
Sex Characteristics
2014
12 Citations (Scopus)

Fibrillar amyloid correlates of preclinical cognitive decline

Stonnington, C. M., Chen, K., Lee, W., Locke, D. E., Dueck, A., Liu, X., Roontiva, A., Fleisher, A. S., Caselli, R. J. & Reiman, E. M., Jan 2014, In : Alzheimer's and Dementia. 10, 1

Research output: Contribution to journalArticle

Apolipoprotein E4
Amyloid
Sex Education
Executive Function
Positron-Emission Tomography
69 Citations (Scopus)

Subjective cognitive decline: Self and informant comparisons

Caselli, R. J., Chen, K., Locke, D. E., Lee, W., Roontiva, A., Bandy, D., Fleisher, A. S. & Reiman, E. M., Jan 2014, In : Alzheimer's and Dementia. 10, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

Symptom Assessment
Psychology
Apolipoprotein E4
Apolipoproteins E
Cognition
39 Citations (Scopus)

The neuropsychology of normal aging and preclinical Alzheimer's disease

Caselli, R. J., Locke, D. E., Dueck, A., Knopman, D. S., Woodruff, B. K., Hoffman-Snyder, C., Rademakers, R. V., Fleisher, A. S. & Reiman, E. M., Jan 2014, In : Alzheimer's and Dementia. 10, 1, p. 84-92 9 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Neuropsychology
Alzheimer Disease
National Institute on Aging (U.S.)
Homozygote
1 Citation (Scopus)

The role of neuropsychology on an epilepsy monitoring unit: a peek behind the "do not disturb" sign.

Kirlin, K. A. & Locke, D. E., 2014, In : The Neurodiagnostic journal. 54, 3, p. 289-298 10 p.

Research output: Contribution to journalArticle

Neuropsychology
Epilepsy
Patient Care
2013
18 Citations (Scopus)
Apolipoprotein E4
Longitudinal Studies
Depression
Apolipoproteins E
Depressive Symptoms
40 Citations (Scopus)

Somatization is associated with deficits in affective theory of mind

Stonnington, C. M., Locke, D. E., Hsu, C. H., Ritenbaugh, C. & Lane, R. D., Jun 2013, In : Journal of Psychosomatic Research. 74, 6, p. 479-485 7 p.

Research output: Contribution to journalArticle

Conversion Disorder
Theory of Mind
Emotions
Anxiety
Somatoform Disorders
2012
27 Citations (Scopus)

Confirming psychogenic nonepileptic seizures with video-EEG: Sex matters

Noe, K. H., Grade, M., Stonnington, C. M., Driver-Dunckley, E. M. & Locke, D. E., Mar 2012, In : Epilepsy and Behavior. 23, 3, p. 220-223 4 p.

Research output: Contribution to journalArticle

Electroencephalography
Seizures
Epilepsy
Sex Characteristics
Personality
9 Citations (Scopus)

Is donepezil effective for multiple sclerosis-related cognitive dysfunction? A critically appraised topic

O'Carroll, C. B., Woodruff, B. K., Locke, D. E., Hoffman-Snyder, C. R., Wellik, K. E., Thaera, G. M., Demaerschalk, B. M. & Wingerchuk, D. M., Jan 2012, In : Neurologist. 18, 1, p. 51-54 4 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Cholinesterase Inhibitors
Placebos
Librarians
Neurology
5 Citations (Scopus)

The influence of impression management scales on the Personality Assessment Inventory in the epilepsy monitoring unit

Purdom, C. L., Kirlin, K. A., Hoerth, M. T., Noe, K. H., Drazkowski, J. F., Sirven, J. I. & Locke, D. E., Dec 2012, In : Epilepsy and Behavior. 25, 4, p. 534-538 5 p.

Research output: Contribution to journalArticle

Personality Assessment
Personality Inventory
Epilepsy
Seizures
Physiologic Monitoring
2011
9 Citations (Scopus)
Apolipoprotein E4
Homozygote
Cognition
Anxiety
Sex Education
46 Citations (Scopus)

Cerebrovascular risk factors and preclinical memory decline in healthy APOE ε4 homozygotes

Caselli, R. J., Dueck, A., Locke, D. E., Sabbagh, M. N., Ahern, G. L., Rapcsak, S. Z., Baxter, L. C., Yaari, R., Woodruff, B. K., Hoffman-Snyder, C., Rademakers, R. V., Findley, S. & Reiman, E. M., Mar 22 2011, In : Neurology. 76, 12, p. 1078-1084 7 p.

Research output: Contribution to journalArticle

Long-Term Memory
Homozygote
Verbal Learning
Heterozygote
Tobacco Products
39 Citations (Scopus)
Movement Disorders
Psychiatry
Seizures
Referral and Consultation
Anxiety
1 Citation (Scopus)
Intelligence
Personality Inventory
Longitudinal Studies
Personality
Anxiety
10 Citations (Scopus)

Estimating the diagnostic value of the trail making test for suboptimal effort in acquired brain injury rehabilitation patients

Powell, M. R., Locke, D. E., Smigielski, J. S. & McCrea, M., Jan 2011, In : Clinical Neuropsychologist. 25, 1, p. 108-118 11 p.

Research output: Contribution to journalArticle

Trail Making Test
Brain Injuries
Rehabilitation
Neuropsychological Tests
Outpatients
14 Citations (Scopus)
MMPI
Seizures
Differential Diagnosis
Electroencephalography
Epilepsy
53 Citations (Scopus)

Longitudinal modeling of frontal cognition in APOE ϵ4 homozygotes, heterozygotes, and noncarriers

Caselli, R. J., Dueck, A., Locke, D. E., Hoffman-Snyder, C. R., Woodruff, B. K., Rapcsak, S. Z. & Reiman, E. M., Apr 19 2011, In : Neurology. 76, 16, p. 1383-1388 6 p.

Research output: Contribution to journalArticle

Homozygote
Heterozygote
Cognition
Verbal Learning
Alzheimer Disease
13 Citations (Scopus)

Randomized comparison of the Personality Assessment Inventory and the Minnesota Multiphasic Personality Inventory-2 in the epilepsy monitoring unit

Locke, D. E., Kirlin, K. A., Wershba, R., Osborne, D., Drazkowski, J. F., Sirven, J. I. & Noe, K. H., Aug 2011, In : Epilepsy and Behavior. 21, 4, p. 397-401 5 p.

Research output: Contribution to journalArticle

Personality Assessment
Personality Inventory
MMPI
Epilepsy
Medical Errors
36 Citations (Scopus)

Treatment of depression in patients with epilepsy

Noe, K. H., Locke, D. E. & Sirven, J. I., Aug 2011, In : Current Treatment Options in Neurology. 13, 4, p. 371-379 9 p.

Research output: Contribution to journalArticle

Epilepsy
Depression
Complementary Therapies
Antidepressive Agents
Vagus Nerve Stimulation
2010
20 Citations (Scopus)

Comparing neuropsychological tasks to optimize brief cognitive batteries for brain tumor clinical trials

Lageman, S. K., Cerhan, J. H., Locke, D. E., Anderson, S. K., Wu, W. & Brown, P. D., Jan 2010, In : Journal of Neuro-Oncology. 96, 2, p. 271-276 6 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Clinical Trials
Neuropsychological Tests
Glioma
Retrospective Studies
4 Citations (Scopus)
Personality Assessment
Personality Inventory
Kidney
Population
2,5-Dimethoxy-4-Methylamphetamine
15 Citations (Scopus)

Objective evaluation of personality and psychopathology in temporal lobe versus extratemporal lobe epilepsy

Locke, D. E., Fakhoury, T. A., Berry, D. T. R., Locke, T. R. & Schmitt, F. A., Feb 2010, In : Epilepsy and Behavior. 17, 2, p. 172-177 6 p.

Research output: Contribution to journalArticle

Temporal Lobe
Psychopathology
Personality Inventory
Personality
Epilepsy
25 Citations (Scopus)

Psychometric Properties of the MMPI-2-RF Somatic Complaints (RC1) Scale

Thomas, M. L. & Locke, D. E., Sep 2010, In : Psychological Assessment. 22, 3, p. 492-503 12 p.

Research output: Contribution to journalArticle

MMPI
Psychometrics
Statistical Factor Analysis
Headache
Epilepsy
32 Citations (Scopus)

The Minnesota Multiphasic Personality Inventory-2-Restructured Form in the epilepsy monitoring unit

Locke, D. E., Kirlin, K. A., Thomas, M. L., Osborne, D., Hurst, D. F., Drazkowski, J. F., Sirven, J. I. & Noe, K. H., Feb 2010, In : Epilepsy and Behavior. 17, 2, p. 252-258 7 p.

Research output: Contribution to journalArticle

MMPI
Epilepsy
Seizures
Psychometrics
Population
2009
4 Citations (Scopus)

Age, family history, and memory and future risk for cognitive impairment

Locke, D. E., Ivnik, R. J., Cha, R. H., Knopman, D. S., Tangalos, E. G., Boeve, B. F., Petersen, R. C. & Smith, G. E., Jan 2009, In : Journal of Clinical and Experimental Neuropsychology. 31, 1, p. 111-116 6 p.

Research output: Contribution to journalArticle

Verbal Learning
Nomograms
Aptitude
Cognitive Dysfunction
Retention (Psychology)
8 Citations (Scopus)

Assessment of patient and caregiver experiences of dementia-related symptoms: Development of the multidimensional assessment of neurodegenerative symptoms questionnaire

Locke, D. E., Dassel, K. B., Hall, G., Baxter, L. C., Woodruff, B. K., Hoffman Snyder, C., Miller, B. L. & Caselli, R. J., Mar 2009, In : Dementia and Geriatric Cognitive Disorders. 27, 3, p. 260-272 13 p.

Research output: Contribution to journalArticle

Symptom Assessment
Caregivers
Dementia
Surveys and Questionnaires
Neurodegenerative Diseases
308 Citations (Scopus)

Longitudinal modeling of age-related memory decline and the APOE ε4 effect

Caselli, R. J., Dueck, A., Osborne, D., Sabbagh, M. N., Connor, D. J., Ahern, G. L., Baxter, L. C., Rapcsak, S. Z., Shi, J., Woodruff, B. K., Locke, D. E., Snyder, C. H., Alexander, G. E., Rademakers, R. V. & Reiman, E. M., Jul 16 2009, In : New England Journal of Medicine. 361, 3, p. 255-263 9 p.

Research output: Contribution to journalArticle

Alleles
Dementia
Alzheimer Disease
Education
2008
77 Citations (Scopus)

Cognitive rehabilitation and problem-solving to improve quality of life of patients with primary brain tumors: A pilot study

Locke, D. E., Cerhan, J. H., Wu, W., Malec, J. F., Clark, M. M., Rummans, T. A. & Brown, P. D., 2008, In : Journal of Supportive Oncology. 6, 8, p. 383-391 9 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Rehabilitation
Quality of Life
Caregivers
Research