Diane F Jelinek, PhD

  • 11070 Citations
  • 63 Scopus h-Index
1981 …2020

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193 Scopus citations

Acquired chromosomal anomalies in chronic lymphocytic leukemia patients compared with more than 50,000 quasi-normal participants

Laurie, C. C., Laurie, C. A., Smoley, S. A., Carlson, E. E., Flinn, I., Fridley, B. L., Greisman, H. A., Gribben, J. G., Jelinek, D. F., Nelson, S. C., Paietta, E., Schaid, D., Sun, Z., Tallman, M. S., Weinshilboum, R., Kay, N. E. & Shanafelt, T. D., Jan 2014, In : Cancer Genetics. 207, 1-2, p. 19-30 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Activating mutations in the N- and K-ras oncogenes differentially affect the growth properties of the IL-6-dependent myeloma cell line ANBL6

Billadeau, D., Liu, P., Jelinek, D., Shah, N., LeBien, T. W. & Van Ness, B., Jun 1 1997, In : Cancer research. 57, 11, p. 2268-2275 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Age at diagnosis and the utility of prognostic testing in patients with chronic lymphocytic leukemia

Shanafelt, T. D., Rabe, K. G., Kay, N. E., Zent, C. S., Jelinek, D. F., Reinalda, M. S., Schwager, S. M., Bowen, D. A., Slager, S. L., Hanson, C. A. & Call, T. G., 2010, In : Cancer. 116, 20, p. 4777-4787 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

Akt inhibitor MK-2206 in combination with bendamustine and rituximab in relapsed or refractory chronic lymphocytic leukemia: Results from the N1087 alliance study

Larsen, J. T., Shanafelt, T. D., Leis, J. F., LaPlant, B., Call, T., Pettinger, A., Hanson, C., Erlichman, C., Habermann, T. M., Reeder, C., Nikcevich, D., Bowen, D., Conte, M., Boysen, J., Secreto, C., Lesnick, C., Tschumper, R., Jelinek, D., Kay, N. E. & Ding, W., Aug 2017, In : American journal of hematology. 92, 8, p. 759-763 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Alternative splicing regulates activation-induced cytidine deaminase (AID): Implications for suppression of AID mutagenic activity in normal and malignant B cells

Wu, X., Darce, J. R., Chang, S. K., Nowakowski, G. S. & Jelinek, D. F., Dec 1 2008, In : Blood. 112, 12, p. 4675-4682 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

A-Miz-ing BCL6

Wu, X. & Jelinek, D. F., Oct 1 2005, In : Nature immunology. 6, 10, p. 964-966 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

AML-1A and AML-1B regulation of MIP-1α expression in multiple myeloma

Choi, S. J., Oba, T., Callander, N. S., Jelinek, D. F. & Roodman, G. D., May 15 2003, In : Blood. 101, 10, p. 3778-3783 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Analysis of clonal B-cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B-chronic lymphocytic leukaemia

Jelinek, D. F., Tschumper, R. C., Geyer, S. M., Bone, N. D., Dewald, G. W., Hanson, C. A., Stenson, M. J., Witzig, T. E., Tefferi, A. & Kay, N. E., 2001, In : British journal of haematology. 115, 4, p. 854-861 8 p.

Research output: Contribution to journalArticle

178 Scopus citations

Analysis of IL-6-mediated growth control of myeloma cells using a gp130 chimeric receptor approach

French, J. D., Tschumper, R. C. & Jelinek, D. F., 2002, In : Leukemia. 16, 6, p. 1189-1196 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Analysis of IL-6-mediated growth control of myeloma cells using a gp130 chimeric receptor approach

French, J. D., Tschumper, R. C. & Jelinek, D. F., 2002, In : Leukemia. 16, 6, p. 1189-1196 8 p.

Research output: Contribution to journalArticle

Analysis of IL-6-mediated growth control of myeloma cells using a gp130 chimeric receptor approach

French, J. D., Tschumper, R. C. & Jelinek, D. F., Jan 1 2002, In : Leukemia. 16, 6, p. 1189-1196 8 p.

Research output: Contribution to journalArticle

Analysis of interleukin 6 (IL-6)-stimulated differential gene expression in human myeloma cells

Tschumper, R. C. & Jelinek, D. F., Dec 1 1996, In : FASEB Journal. 10, 6, p. A1460

Research output: Contribution to journalArticle

Analysis of the differential effects of Interferon-alpha (IFN-α) on myeloma cell proliferation

Arora, T. & Jelinek, D. F., Dec 1 1996, In : FASEB Journal. 10, 6, p. A1460

Research output: Contribution to journalArticle

A promising approach for treatment of tumor-induced bone diseases: Utilizing bisphosphonate derivatives of nucleoside antimetabolites

Reinholz, M. M., Zinnen, S. P., Dueck, A. C., Dingli, D., Reinholz, G. G., Jonart, L. A., Kitzmann, K. A., Bruzek, A. K., Negron, V., Abdalla, A. K., Arendt, B. K., Croatt, A. J., Sanchez-Perez, L., Sebesta, D. P., Lönnberg, H., Yoneda, T., Nath, K. A., Jelinek, D. F., Russell, S. J., Ingle, J. N. & 4 others, Spelsberg, T. C., Dixon, H. B. F., Karpeisky, A. & Lingle, W. L., Jul 2010, In : Bone. 47, 1, p. 12-22 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

A recombinant IL-4-Pseudomonas exotoxin inhibits protein synthesis and overcomes apoptosis resistance in human CLL B cells

Kay, N. E., Bone, N. D., Lee, Y. K., Jelinek, D. F., Leland, P., Battle, T. E., Frank, D. A. & Puri, R. K., Sep 1 2005, In : Leukemia Research. 29, 9, p. 1009-1018 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

A role for BLyS in the activation of innate immune cells

Sook, K. C., Arendt, B. K., Darce, J. R., Wu, X. & Jelinek, D. F., Oct 15 2006, In : Blood. 108, 8, p. 2687-2694 8 p.

Research output: Contribution to journalArticle

76 Scopus citations

A Role for Insulin-Like Growth Factor in the Regulation of IL-6-Responsive Human Myeloma Cell Line Growth

Jelinek, D. F., Witzig, T. E. & Arendt, B. K., Dec 1 1997, In : Journal of Immunology. 159, 1, p. 487-496 10 p.

Research output: Contribution to journalArticle

89 Scopus citations

A role for Janus kinases in crosstalk between ErbB3 and the interferon-alpha signaling complex in myeloma cells

Walters, D. K. & Jelinek, D. F., Feb 12 2004, In : Oncogene. 23, 6, p. 1197-1205 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

A Role for Phosphatidylinositol 3-Kinase in Generating T Cell Help for B Cell Growth and Differentiation

Aagaard-Tillery, K. M. & Jelinek, D. F., Oct 1 1996, In : Journal of Immunology. 157, 7, p. 2769-2778 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union

Grover, R. K., Zhu, X., Nieusma, T., Jones, T., Boero, I., MacLeod, A. S., Mark, A., Niessen, S., Kim, H. J., Kong, L., Assad-Garcia, N., Kwon, K., Chesi, M., Smider, V. V., Salomon, D. R., Jelinek, D. F., Kyle, R. A., Pyles, R. B., Glass, J. I., Ward, A. B. & 2 others, Wilson, I. A. & Lerner, R. A., 2014, In : Science. 343, 6171, p. 656-661 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Atypical expression of ErbB3 in myeloma cells: Cross-talk between ErbB3 and the interferon-α signaling complex

Walters, D. K., French, J. D., Arendt, B. K. & Jelinek, D. F., Jun 5 2003, In : Oncogene. 22, 23, p. 3598-3607 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Autoimmune cytopenia in chronic lymphocytic leukemia/small lymphocytic lymphoma: Changes in clinical presentation and prognosis

Zent, C. S., Ding, W., Reinalda, M. S., Schwager, S. M., Hoyer, J. D., Bowen, D. A., Jelinek, D. F., Tschumper, R. C., Call, T. G., Shanafelt, T. D., Kay, N. E. & Slager, S. L., 2009, In : Leukemia and Lymphoma. 50, 8, p. 1261-1268 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

B-cell count and survival: Differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome

Shanafelt, T. D., Kay, N. E., Jenkins, G., Call, T. G., Zent, C. S., Jelinek, D. F., Morice, W. G., Boysen, J., Zakko, L., Schwager, S., Slager, S. L. & Hanson, C. A., 2009, In : Blood. 113, 18, p. 4188-4196 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma

Correia, C., Schneider, P. A., Dai, H., Dogan, A., Maurer, M. J., Church, A. K., Novak, A. J., Feldman, A. L., Wu, X., Ding, H., Meng, X. W., Cerhan, J. R., Slager, S. L., Macon, W. R., Habermann, T. M., Karp, J. E., Gore, S. D., Kay, N. E., Jelinek, D. F., Witzig, T. E. & 2 others, Nowakowski, G. S. & Kaufmann, S. H., Jan 22 2015, In : Blood. 125, 4, p. 658-667 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules

Kay, N. E., Bone, N. D., Tschumper, R. C., Howell, K. H., Geyer, S. M., Dewald, G. W., Hanson, C. A. & Jelinek, D. F., 2002, In : Leukemia. 16, 5, p. 911-919 9 p.

Research output: Contribution to journalArticle

115 Scopus citations

Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2

Arendt, B. K., Ramirez-Alvarado, M., Sikkink, L. A., Keats, J. J., Ahmann, G. J., Dispenzieri, A., Fonseca, R., Ketterling, R. P., Knudson, R. A., Mulvihill, E. M., Tschumper, R. C., Wu, X., Zeldenrust, S. R. & Jelinek, D. F., Sep 1 2008, In : Blood. 112, 5, p. 1931-1941 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

B lymphocyte stimulator regulates adaptive immune responses by directly promoting dendritic cell maturation

Chang, S. K., Mihalcik, S. A. & Jelinek, D. F., 2008, In : Journal of Immunology. 180, 11, p. 7394-7403 10 p.

Research output: Contribution to journalArticle

Open Access
40 Scopus citations
72 Scopus citations

Brief report: Natural history of individuals with clinically recognized monoclonal B-cell lymphocytosis compared with patients with Rai 0 chronic lymphocytic leukemia

Shanafelt, T. D., Kay, N. E., Rabe, K. G., Call, T. G., Zent, C. S., Maddocks, K., Jenkins, G., Jelinek, D. F., Morice, W. G., Boysen, J., Schwager, S., Bowen, D., Slager, S. L. & Hanson, C. A., Aug 20 2009, In : Journal of Clinical Oncology. 27, 24, p. 3959-3963 5 p.

Research output: Contribution to journalArticle

102 Scopus citations

CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells

Walters, D. K., Arendt, B. K. & Jelinek, D. F., 2013, In : Cell Cycle. 12, 19, p. 3364-3372 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation

Pittner, B. T., Shanafelt, T. D., Kay, N. E. & Jelinek, D. F., Dec 2005, In : Leukemia. 19, 12, p. 2264-2272 9 p.

Research output: Contribution to journalArticle

41 Scopus citations
119 Scopus citations

CD40 expression in malignant plasma cells: Role in stimulation of autocrine IL-6 secretion by a human myeloma cell line

Westendorf, J. J., Ahmann, G. J., Armitage, R. J., Spriggs, M. K., Lust, J. A., Greipp, P. R., Katzmann, J. A. & Jelinek, D. F., Jan 1 1994, In : Journal of Immunology. 152, 1, p. 117-128 12 p.

Research output: Contribution to journalArticle

107 Scopus citations

CD49d associates with nodal presentation and subsequent development of lymphadenopathy in patients with chronic lymphocytic leukaemia

Strati, P., Parikh, S. A., Chaffee, K. G., Achenbach, S. J., Slager, S. L., Call, T. G., Ding, W., Jelinek, D. F., Hanson, C. A., Kay, N. E. & Shanafelt, T. D., Jul 2017, In : British journal of haematology. 178, 1, p. 99-105 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: A prognostic parameter with therapeutic potential

Shanafelt, T. D., Geyer, S. M., Bone, N. D., Tschumper, R. C., Witzig, T. E., Nowakowski, G. S., Zent, C. S., Call, T. G., LaPlant, B., Dewald, G. W., Jelinek, D. F. & Kay, N. E., Mar 2008, In : British journal of haematology. 140, 5, p. 537-546 10 p.

Research output: Contribution to journalArticle

111 Scopus citations

Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain

Walters, D. K., Arendt, B. K., Tschumper, R. C., Wu, X. & Jelinek, D. F., Jan 2018, In : Experimental Hematology. 57, p. 42-49.e1

Research output: Contribution to journalArticle

1 Scopus citations

Chromosome anomalies detected by interphase fluorescence in situ hybridization: Correlation with significant biological features of B-cell chronic lymphocytic leukaemia

Dewald, G. W., Brockman, S. R., Paternoster, S. F., Bone, N. D., O'Fallon, J. R., Allmer, C., James, C. D., Jelinek, D. F., Tschumper, R. C., Hanson, C. A., Pruthi, R. K., Witzig, T. E., Call, T. G. & Kay, N. E., Apr 2003, In : British journal of haematology. 121, 2, p. 287-295 9 p.

Research output: Contribution to journalArticle

197 Scopus citations

Chronic lymphocytic leukemia in young (≤ 55 years) patients: A comprehensive analysis of prognostic factors and outcomes

Parikh, S. A., Rabe, K. G., Kay, N. E., Call, T. G., Ding, W., Schwager, S. M., Bowen, D. A., Conte, M., Jelinek, D. F., Slager, S. L. & Shanafelt, T. D., Jan 1 2014, In : Haematologica. 99, 1, p. 140-147 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Chronic lymphocytic leukemia with mutated IGHV4-34 receptors: Shared and distinct immunogenetic features and clinical outcomes

Xochelli, A., Baliakas, P., Kavakiotis, I., Agathangelidis, A., Sutton, L. A., Minga, E., Ntoufa, S., Tausch, E., Yan, X. J., Shanafelt, T., Plevova, K., Boudjogra, M., Rossi, D., Davis, Z., Navarro, A., Sandberg, Y., Vojdeman, F. J., Scarfo, L., Stavroyianni, N., Sudarikov, A. & 42 others, Veronese, S., Tzenou, T., Karan-Djurasevic, T., Catherwood, M., Kienle, D., Chatzouli, M., Facco, M., Bahlo, J., Pott, C., Pedersen, L. B., Mansouri, L., Smedby, K. E., Chu, C. C., Giudicelli, V., Lefranc, M. P., Panagiotidis, P., Juliusson, G., Anagnostopoulos, A., Vlahavas, I., Antic, D., Trentin, L., Montillo, M., Niemann, C., Dohner, H., Langerak, A. W., Pospisilova, S., Hallek, M., Campo, E., Chiorazzi, N., Maglaveras, N., Oscier, D., Gaidano, G., Jelinek, D. F., Stilgenbauer, S., Chouvarda, I., Darzentas, N., Belessi, C., Davi, F., Hadzidimitriou, A., Rosenquist, R., Ghia, P. & Stamatopoulos, K., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 5292-5301 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma

Kyle, R. A., Remstein, E. D., Therneau, T. M., Dispenzieri, A., Kurtin, P. J., Hodnefield, J. M., Larson, D. R., Plevak, M. F., Jelinek, D. F., Fonseca, R., Melton, L. J. & Rajkumar, S. V., Jun 21 2007, In : New England Journal of Medicine. 356, 25, p. 2582-2590 9 p.

Research output: Contribution to journalArticle

484 Scopus citations

Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: A retrospective multicentre study

Baliakas, P., Hadzidimitriou, A., Sutton, L. A., Minga, E., Agathangelidis, A., Nichelatti, M., Tsanousa, A., Scarfò, L., Davis, Z., Yan, X. J., Shanafelt, T., Plevova, K., Sandberg, Y., Vojdeman, F. J., Boudjogra, M., Tzenou, T., Chatzouli, M., Chu, C. C., Veronese, S., Gardiner, A. & 28 others, Mansouri, L., Smedby, K. E., Pedersen, L. B., van Lom, K., Giudicelli, V., Francova, H. S., Nguyen-Khac, F., Panagiotidis, P., Juliusson, G., Angelis, L., Anagnostopoulos, A., Lefranc, M. P., Facco, M., Trentin, L., Catherwood, M., Montillo, M., Geisler, C. H., Langerak, A. W., Pospisilova, S., Chiorazzi, N., Oscier, D., Jelinek, D. F., Darzentas, N., Belessi, C., Davi, F., Rosenquist, R., Ghia, P. & Stamatopoulos, K., Jan 1 2014, In : The Lancet Haematology. 1, 2, p. e74-e84

Research output: Contribution to journalArticle

56 Scopus citations

Cloning and regulation of cholesterol 7α-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis

Jelinek, D. F., Andersson, S., Slaughter, C. A. & Russell, D. W., 1990, In : Journal of Biological Chemistry. 265, 14, p. 8190-8197 8 p.

Research output: Contribution to journalArticle

273 Scopus citations

Cloning of the human cholesterol 7α-hydroxylase gene (CYP7) and localization to chromosome 8q11-q12

Cohen, J. C., Cali, J. J., Jelinek, D. F., Mehrabian, M., Sparkes, R. S., Lusis, A. J., Russell, D. W. & Hobbs, H. H., Sep 1992, In : Genomics. 14, 1, p. 153-161 9 p.

Research output: Contribution to journalArticle

85 Scopus citations

Clonotypic light chain peptides identified for monitoring minimal residual disease in multiple myeloma without bone marrow aspiration

Robert Bergen, H., Dasari, S., Dispenzieri, A., Mills, J. R., Ramirez-Alvarado, M., Tschumper, R. C., Jelinek, D. F., Barnidge, D. R. & Murray, D. L., Jan 2016, In : Clinical chemistry. 62, 1, p. 243-251 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Coexistence of Aneuploid Subclones within a Myeloma Cell Line That Exhibits Clonal Immunoglobulin Gene Rearrangement: Clinical Implications

Jelinek, D. F., Ahmann, G. J., Greipp, P. R., Jalal, S. M., Westendorf, J. J., Katzmann, J. A., Kyle, R. A. & Lust, J. A., Nov 1993, In : Cancer research. 53, 21, p. 5320-5327 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia

Kay, N. E., Geyer, S. M., Call, T. G., Shanafelt, T. D., Zent, C. S., Jelinek, D. F., Tschumper, R., Bone, N. D., Dewald, G. W., Lin, T. S., Heerema, N. A., Smith, L., Grever, M. R. & Byrd, J. C., Jan 15 2007, In : Blood. 109, 2, p. 405-411 7 p.

Research output: Contribution to journalArticle

252 Scopus citations

Comparative activation requirements of human peripheral blood, spleen, and lymph node B cells

Jelinek, D. F. & Lipsky, P. E., Jan 1 1987, In : Journal of Immunology. 139, 4, p. 1005-1013 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: Results from the US intergroup phase III trial E2997

Grever, M. R., Lucas, D. M., Dewald, G. W., Neuberg, D. S., Reed, J. C., Kitada, S., Flinn, I. W., Tallman, M. S., Appelbaum, F. R., Larson, R. A., Paietta, E., Jelinek, D. F., Gribben, J. G. & Byrd, J. C., Mar 1 2007, In : Journal of Clinical Oncology. 25, 7, p. 799-804 6 p.

Research output: Contribution to journalArticle

276 Scopus citations

Comprehensive assessment of potential multiple myeloma immunoglobulin heavy chain V-D-J intraclonal variation using massively parallel pyrosequencing

Tschumper, R. C., Asmann, Y. W., Hossain, A., Huddleston, P. M., Wu, X., Dispenzieri, A., Eckloff, B. W. & Jelinek, D. F., Apr 2012, In : Oncotarget. 3, 4, p. 502-513 12 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations